OIT (N-OCTYL ISOTHIAZOLINONE)

OIT (OCTYL ISOTHIAZOLINE)

Cas No : 26530-20-1

SYNONYMS: 2,3-Octylisothiazolone; 2-Octyl-4-isothiazolin-3-one; Octhilinone; 2-Octyl-3(2H)-isothiazolone; 2-n-Octyl-4-isothiazolin-3-one; Kathon 893; Kathon LM; 2-Octyl-2H-isothiazol-3-one; 2-Octyl-3-isothiazolone; 2-n-Octyl-4-isothiazolin-3-one; Other RN: 122667-23-6, 12673-72-2, 245125-70-6, 249757-59-3, 53028-82-3, 68480-30-8 (hydrochloride); C11H19NOS; oktil izotiazolinon; OIY; oktilizotiazolinon; oktil izo tiazolinon; n-oktil izotiazolinon; kathon-893; athon-lm; Acticide 45, acticide epw, acticide epw 1, acticide ota 20, acticide otp 10, acticide otw, acticide dw, oit, oktil izotiazolin, oktil, 2-Octyl-2H-isothiazol-3-one, N- OCTYL ISOTHIAZOLINONE, nipacide oit, cas no : 26530-20-1; 2-Octyl-2H-isothiazol-3-one, biocide, biyosit. Octhilinone 26530-20-1,2-octylisothiazol-3(2H)-one,2-n-Octyl-4-isothiazolin-3-one,2-Octyl-4-isothiazolin-3-one,2-Octyl-3-isothiazolone,Pancil,2-Octyl-2H-isothiazol-3-one,3(2H)-Isothiazolone, 2-octyl-,2-Octyl-3(2H)-isothiazolone,Kathon 893,Skane 8,Skane M-8,Kathon 893F,Micro-chek skane,Kathon LM,Microbicide M-8,Micro-chek 11,Micro-chek 11D,Kathon SP 70,Kathon LP preservative,Kathon 4200,Pancil-T,Skane M8,2-octyl-1,2-thiazol-3-one,Caswell No. 613C,4-Isothiazolin-3-one, 2-octyl-,UNII-4LFS24GD0V,Vinylzene IT 3000DIDP,Octyl-3(2H)-isothiazolone,RH 893,Octhilinone [ANSI:BSI:ISO],CCRIS 6082,EINECS 247-761-7,2-Octyl-3-isothioazolone,2-Octyl-3 isothiazolinone,Octyl-4-isothiazol-3-one,EPA Pesticide Chemical Code 099901,2-n-Octyl-3-isothiazolone,BRN 1211137,4LFS24GD0V,MLS002415697,CHEBI:81936,2-octyl-1,2-thiazol-3(2H) one,SMR001370885,DSSTox_CID_5805,DSSTox_RID_77928,DSSTox_GSID_25805,W 107168,Kathon,CAS-26530-20-1,C11H19NOS,Pancil T,Skane M 8,ACMC-1CDE4,Vinyzene IT 3000DIDP,SCHEMBL15648,cid_33528,KSC163A4D,SCHEMBL396433,CHEMBL1562104,DTXSID1025805,BDBM66023,HSDB 6713,KS-00000ZYZ,ZINC2012904,Tox21_201459,Tox21_300566,ANW-26014,RH-893,AKOS015897428,LS-1106,ACM25339531,ACM26530201,NCGC00091875-01,NCGC00091875-02,NCGC00091875-03,NCGC00091875-04,NCGC00091875-05,NCGC00254466-01,NCGC00259010-01,AK109069,AS-11894,CC-11727,Octhilinone 10 microg/mL in Acetonitrile,AX8013468,DB-028182,FT-0613248,NS00000270,O0343,O0378,C18752,K-6861,530O201,C-24530,Q2013949,2-Octyl-4-isothiazolin-3-one, PESTANAL(R), analytical standard,OCTYLISOTHIAZOLINONE;Octhilinone;2-Octyl-3(2H)-isothiazolone;2-octyl-2H-isothiazol-3-one hydrochloride, 2-octil-2H-isotiazol-3-ona (es), 2-Octil-2H-isotiazol-3-ona (OIT) (es),2-octil-2H-isotiazol-3-onă (OIT) (ro),2-octil-2H-isotiazole-3-ona (pt),2-octil-2H-izotiiazol-3-ona (ro),2-octyl-2H-isothiazol-3-on (da),2-octyl-2H-isothiazol-3-on (OIT) (da),2-octyl-2H-isothiazol-3-one (OIT) (mt),2-octyl-2H-isothiazole-3-one (OIT) (fr),2-octyl-2H-isothiazool-3-on (nl),2-Octyl-2H-isothiazool-3-on (OIT) (nl),2-oktil-2H-izotiazol-3-on (hr),2-oktil-2H-izotiazol-3-on (hu),2-oktil-2H-izotiazol-3-on (OIT) (hr),2-oktil-2H-izotiazol-3-onas (lt),2-oktil-2H-izotiazol-3-onas (OIT) (lt),2-Oktil-2H-izotiazol-3-ons (OIT) (lv),2-oktil-2H-izotiazolons-3 (lv),2-oktyl-2H-isotiazol-3-on (no),2-oktyl-2H-isotiazol-3-on (OIT) (sv),2-oktyl-2H-izotiazol-3-ón (sk),2-oktyl-2H-izotiazol-3-ón (OIT) (sk),2-oktylo-2H-izotiazol-3-on (OIT) (pl),2-oktyloizotiazol-3(2H)-on (pl),2-oktyltetrahydroisothiazol-3-on (cs),2-oktyltetrahydroisothiazol-3-on (OIT) (cs),2-oktyyli-2H-isotiatsol-3-oni (OIT) (fi),2-oktyyli-2H-isotiatsoli-3-oni (fi),2-oktüül-2H-isotiasool-3-oon (et),2-oktüül-2H-isotiasool-3-oon (OIT) (et),2-ottil-2H-isotiazol-3-one (it),2-ottil-2H-isotiazol-3-one (OIT) (it),2-οκτυλ-2H-ισοθειαζολόνη-3 (OIT) (el),2-οκτυλο-2H-ισοθειαζολ-3-όνη (el),2-октил-2H-изотиазол-3-он (bg),2-октил-2H-изотиазол-3-он (OIT) (bg),octhilinon (da),Octhilinon (ISO) (de),octhilinone (ISO) (cs),octhilinone (ISO);2-octyl-2H-isothiazol-3-one (fr),octilinon (ISO) (ro),oktilinon (ISO), 4,5-Dichloro-2-octyl-isothiazolone, (hr),oktilinonas (ISO) (lt),oktilinons (ISO) (lv),oktilinoon (ISO) (et),oktilinón (ISO) (sk),октилинон (ISO) (bg), DCOIT;C-9211;DCOIT-30;DCOIT-99;DCOIT 97;KATHON287;kathon 930;duracide l;Kathon 287T;Sea-Nine 211, CB4279833, C11H17Cl2NOS, 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one, 5-Dichloro-2-octyl-3(2H)-isothiazolone2-(4,5-dichlorooctyl)-2,3-dihydro-1,2-thiazol-3-one4,5-dichloro-2-n-octDCOIT-99DCOIT-304,5-Dichloro-2-n-octyl-4-isothiazolin-3-oneKathon,287T4,5-DICHLORO-2-N-OCTYL-3(2H)-ISOTHIAZOLONE4,5-dichloro-2-octyl-3(2h) isothiazolone4,5-Dichloro-2-octyl-isothiazolonekathon930Dichloro-2-n-octyl-3(2H)-isothiazoloneduracidel4,5-dichloro-2n-octyl-3-isothiazolone4,5-Dichloro-N-octyl-3(2H)-isothiazoloneDCOIT4,5-dichloro-2-octyl-2H-isothiazol-3-one4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one4,5-Dichloro-N-octyl–4-isothiazolin-3-one4,5-Dichloro-N-octyl–4-isothiazolin-3-one4,5-Dichloro-2-Octyl-3-Isothiazolone4,5-dichloro-2n-octyl-3-isothiazolone(DCOIT)4,5-DICHLORO-2-N-OCTYL-ISOTHIAZOLINONEKATHON2874,5-Dichlor-2-octyl-2H-isothiazol-3-on4,5-dichloro-2-n-octyl-4-isothiazolone-3-one4,5-dichloro-2-octyl-3(2h)-isothiazolonkathon 925(4,5-dichloro-2-n-octyl-4-isothiazolin-3-one)4,5-Dichloro-N-octyl-4-isothiazol-3-one4,5-Dichloro-2-octylisothiazol-3(2H)-oneC-9211Sea-Nine 2114,5-DICHLORO-2-N-OCTYLISOTHIAZOL-3-ONE4.5-DICHLORO-2H-OCTYL-3(2H)-ISOTHIAZOLONEAnti-foulant C-9211mCaswell no. 314bEinecs 264-843-8Epa pesticide chemical code 1281014,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT)3(2H)-Isothiazolone, 4,5-dichloro-2-octyl-DCOIT 974,5-Dichloro-2-octyl-isothiazoloneDCOIT4,5-dichloro-2-octyl-3H-isothiazole 1-oxide4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one>64359-81-5C11H17Cl2NOS, 3(2H)-ISOTHIAZOLONE, 2-OCTYL 4-ISOTHIAZOLIN-3-ONE, 2-OCTYL-,KATHON 4200,KATHON 893,KATHON LM,KATHON LP PRESERVATIVE,KATHON SP 70,MICRO-CHEK 11,MICRO-CHEK 11D,MICRO-CHEK SKANE,2-N-OCTYL-3-ISOTHIAZOLONE,2-N-OCTYL-4-ISOTHIAZOLIN-3-ONE,2-N-OCTYLISOTHIAZOLIN-3-NE,OCTHILINONE,2-OCTYL-3(2H)ISOTHIAZOLONE,2-OCTYL-3-ISOTHIAZOLINONE,2-OCTYL-3-ISOTHIAZOLONE,2-OCTYL-4-ISOTHIAZOLIN-3-ONE,2-OCTYL-4-ISOTHIAZOLINONE,PANCIL,PANCIL T,PANCIL-T,RH 893,SKANE 8,SKANE HQ,SKANE M 8,SKANE M8,VINYZENE IT 3000DIDP Isothiazole Thiazole thiazol-3-one Isothiazolinones 2-Methyl-4-isothiazolin-3-one hydrochloride decene 5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride 4,5-Dichloro-2-octyl-isothiazolone OCTYL GLUCOSIDE CAPRYLYL PYRROLIDONE Octyldodecyldimethylammonium chloride Kathon Dichloroacetonitrile 5-Chloro-2-methyl-3(2H)-isothiazolone with 2-methyl-3(2H)-isothiazolone Methylisothiazolinone 2-Octyl-2H-isothiazol-3-one 2′,4′-Dichloroacetophenone, 2-oktil-2H-izotiazol-3-onas (OIT) (lt),2-Oktil-2H-izotiazol-3-ons (OIT) (lv),2-oktil-2H-izotiazolons-3 (lv),2-oktyl-2H-isotiazol-3-on (no),2-oktyl-2H-isotiazol-3-on (OIT) (sv),2-oktyl-2H-izotiazol-3-ón (sk),2-oktyl-2H-izotiazol-3-ón (OIT) (sk),2-oktylo-2H-izotiazol-3-on (OIT)(pl),2-oktyloizotiazol-3(2H)-on(pl),2-oktyltetrahydroisothiazol-3-on(cs),2 oktyltetrahydroisothiazol-3-on (OIT) (cs),2-oktyyli-2H-isotiatsol-3-oni (OIT) (fi),2-oktyyli-2H-isotiatsoli-3-oni (fi),2-oktüül-2H-isotiasool-3-oon (et) OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

OIT (OCTYL ISOTHIAZOLINE)

Isothiazolinones containing sulfur atom (S), nitrogen (N), oxygen (O) at 3 position and hydrogen (H) can find application for making broad-spectrum biocides and preservatives such as antiseptic agents, bactericides, slimicides, and fungicides. The biggest application is in paint industry especially marine antifouling agent. They are also used in adhesives, cutting oils, water systems, cosmetics, household goods and wound protectant for pruning cuts. They are also used as pulp and wood impregnating agents as well as in leather, fur and polymer process. It is known to cause allergy and chemical burn if high concentration is used in personal care products and cosmetics. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Octylisothiazolinone is used almost exclusively as a preservative in latex paints, but a small proportion is also used as a preservative in the leather and fur industries. Isothiazolines are also used as slime control agents in the pulp industry and as wood impregnating agents. Low concentrations, mostly <<0.01 %, of isothiazolines are present in a large number of products, which means that the volumes reported are averages with a wide interval. Concentrations are often given as maximum values, which compounds the uncertainty regarding these volumes. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

2-Octyl-2H-isothiazol-3-one Chemical Properties,Uses,Production

Description

This isothiazolione, octylisothiazolinone, is contained in relatively fewer products than other isothiazolinones.

Chemical Properties

Yellow solid or clear dark amber liquid. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Chemical Properties OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Light Yellow Oil

Uses

Fungicide. Antimicrobial agent

Uses

Fungicide. Biocide in cooling-tower water, paints, cutting oils, cosmetics and shampoo; for leather preservation.

Uses

2-n-Octyl-4-isothiazolin-3-one is a mildeweide; bactericide; fungicide; biocide in cooling-tower water; in paints, cutting oils, cosmetics, and shampoos; leather preservation; wound protectant for pruning cuts.

Definition

ChEBI: A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It i no longer approved for use within the European Union.

General Description

Clear dark amber liquid. Used as a fungicide.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Octyl-2H-isothiazol-3-one reacts as an isothiocyanate. Isothiocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat.

Fire Hazard

2-Octyl-2H-isothiazol-3-one is probably combustible. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Contact allergens

This isothiazolinone, contained in relatively few products compared to other isothiazolinones, is used in cleaning and polishing agents, latex paints, stains, adhesives, wood and leather preservatives, metalworking fluids (cutting oils), and plastic manufacture.

Safety Profile

Moderately toxic by ingestion and skin contact. A skin and severe eye irritant. A rmldewcide. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also KETONES.

Potential Exposure

Isothiazolone/isothiocyanate/heteroaramatic fungicide and microbiocide used on textiles, in metalworking fluids, and some water thinned paints. Its use as a fungicide on cotton was canceled in the United States and the tolerances were revoked in 1998. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Shipping

UN2922 Corrosive liquids, toxic, n.o.s., Hazard class: 8; Labels: 8-Corrosive material, 6.1-Poisonous materials.

Incompatibilities

Oxidizers. Contact with hydrogen peroxide may form explosive material. Isothiocyanates are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Ketones behave a weak acid. Forms water soluble alkali metal salts. Ketones are reactive with many acids and bases liberating heat and flammable gases. The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable hydrogen gas and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, nitric acid, and perchloric acid.

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.

2-Octyl-2H-isothiazol-3-one Preparation Products And Raw materials

3.2Experimental Properties HelpNew Window

3.2.1Physical Description HelpNew Window

2-octyl-3-isothiazolone is a clear dark amber liquid. Used as a fungicide.

CAMEO Chemicals

3.2.2Color/Form HelpNew Window

Liquid

American Conference of Governmental Industrial Hygienists. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH, Cincinnati, OH 2012, p. 1256

Hazardous Substances Data Bank (HSDB)

Light, golden yellow, clear liquid

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

3.2.3Odor HelpNew Window

Very weak, sharp smell

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010) OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Hazardous Substances Data Bank (HSDB)

3.2.4Boiling Point HelpNew Window

248 °F at 0.01 mm Hg (NTP, 1992)

National Toxicology Program, Institute of Environmental Health Sciences, National Institutes of Health (NTP). 1992. National Toxicology Program Chemical Repository Database. Research Triangle Park, North Carolina.

CAMEO Chemicals

342 °C at 101.325 kPa (est)

ECHA; Search for Chemicals. Octhilinone (36530-20-1) Registered Substances Dossier. European Chemical Agency. Available from, as of July 9, 2018: http://echa.europa.eu/

Hazardous Substances Data Bank (HSDB)

3.2.5Melting Point HelpNew Window

15 °C at 101.325 kPa

ECHA; Search for Chemicals. Octhilinone (36530-20-1) Registered Substances Dossier. European Chemical Agency. Available from, as of July 9, 2018: http://echa.europa.eu/ OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Hazardous Substances Data Bank (HSDB)

3.2.6Flash Point HelpNew Window

greater than 200 °F (NTP, 1992)

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

CAMEO Chemicals

3.2.7Solubility HelpNew Window

less than 1 mg/mL at 66° F (NTP, 1992)

CAMEO Chemicals

0.00 M

TOMLIN,C (1994)

EPA DSSTox

In distilled water, 500 mg/L at 25 °C

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

In toluene >800, ethyl acetate >900, hexane 64 (all in g/L at 25 °C)

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB) OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

3.2.8Density HelpNew Window

1.04 at 60.3 °F (NTP, 1992)

CAMEO Chemicals

1.03

USEPA/OPP; Pesticide Chemical Search. RED. Octhilinone. (26530-20-1). Sept 2007. EPA 739-R-07-008. Washington, DC: Environmental Protection Agency, Office of Pesticide Programs. Available from, as of July 9, 2018: http://iaspub.epa.gov/apex/pesticides/f?p=chemicalsearch:1

Hazardous Substances Data Bank (HSDB)

3.2.9Vapor Pressure HelpNew Window

2.98 mm Hg at 77 °F (NTP, 1992)

CAMEO Chemicals

3.68e-05 mmHg

EPA DSSTox

3.68X10-5 mm Hg (4.9 mPa) at 25 °C

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

3.2.10LogP HelpNew Window

2.45 (LogP)

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),

TOMLIN,C (1994)

EPA DSSTox

log Kow = 2.45 at 24 °C

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

3.2.11Stability/Shelf Life HelpNew Window

Stable under recommended storage conditions. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Sigma-Aldrich; Safety Data Sheet for 2-Octyl-4-isothiazolin-3-one. Product Number: 46078, Version 5.2 (Revision Date 03/13/2015). Available from, as of June 15, 2018: http://www.sigmaaldrich.com/safety-center.html

Hazardous Substances Data Bank (HSDB)

3.2.12Decomposition HelpNew Window

When heated to decomposition it emits very toxic fumes of /sulfur oxides and nitrogen oxides/.

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),Lewis, R.J. Sr. (ed) Sax’s Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 2769

Hazardous Substances Data Bank (HSDB)

3.2.13Viscosity HelpNew Window

48.04 sq mm.s at 20 °C; 17.94 sq mm.s at 30 °C

3.2.14pH HelpNew Window

pH = 3.4

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),

Hazardous Substances Data Bank (HSDB)

3.2.15Kovats Retention Index HelpNew Window

Semi-standard non-polar 1822.6, 1849

NIST Mass Spectrometry Data Center

3.2.16Other Experimental Properties HelpNew Window

BP: 120 °C at 0.01 mm Hg

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

Relative density: 1.04 at 15 °C; log Pow: 2.61 at 25 °C, pH 7

ECHA; Search for Chemicals. Octhilinone (36530-20-1) Registered Substances Dossier. European Chemical Agency. Available from, as of July 9, 2018: http://echa.europa.eu/

Hazardous Substances Data Bank (HSDB)

log Kow = 3.42

Hazardous Substances Data Bank (HSDB)

Stable to light

MacBean C, ed; e-Pesticide Manual. 15th ed., ver. 5.1, Alton, UK; British Crop Protection Council. Octhilinone (26530-20-1) (2008-2010)

Hazardous Substances Data Bank (HSDB)

Henry’s Law constant = 2.07X10-8 atm-cu m/mol at 25 °C (est) OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

US EPA; Estimation Program Interface (EPI) Suite. Ver. 4.11. Nov, 2012. Available from, as of July 9, 2018: http://www2.epa.gov/tsca-screening-tools

Hydroxyl radical reaction rate constant = 2.94X10-11 cu cm/molec-sec at 25 °C (est)

US EPA; Estimation Program Interface (EPI) Suite. Ver. 4.11. Nov, 2012. Available from, as of July 9, 2018: http://www2.epa.gov/tsca-screening-tools

Hazardous Substances Data Bank (HSDB)

Ozone reaction rate constant = 1.75X10-18 cu cm/molec-sec at 25 °C (est)

US EPA; Estimation Program Interface (EPI) Suite. Ver. 4.11. Nov, 2012. Available from, as of July 9, 2018: http://www2.epa.gov/tsca-screening-tools

Hazardous Substances Data Bank (HSDB)

Chemical Name: 2-n-octyl-4-isothiazolin-3-one; 2-Octyl-2H-isothiazol-3-one; Octylisothiazolinone; Kathon 893

CAS NO.: 26530-20-1

Molecular formula: C11H19NOS

Molecular weight: 213.34

Technical index

Appearance

Pale brown liquid

Content of active substance %

≥98%

PH value

4.0-7.0

Density(25℃) g/cm3

1.00-1.05

COA Download: Here

MSDS: Contact us for MSDS file.

Applications

It is mainly used as biocides and preservatives for coatings, paints, resins emulsions, oil water emulsions, photo-chemicals, in Paint, inks, lubricant, shoes cream, leather chemical, wood product and cultural relic protection etc.

Features:

1. Broad-spectrum sterilization,with good inhibiting capacity towards bacteria, mould, Fungus and ferment.

2. Lox toxicity,long lasting effect: Free of formaldehyde，No smell.

3. Strong Bactericidal power:with strong capability of killing moulds, effect is obvious than the traditional Fungicide,is a kind of proper replacement of traditional film Fungicide.

4. No impact to environment. The products can be degrade naturally to Non-toxic substance,will not cause pollution to environment.

Safety/Operation/Toxicity：

Avoid any contact with the skin. Wear protective clothes, goggles, and rubber gloves in operation. Once touch, will be sensitive to skin.Irritating to the skin and eyes.

Remarks:

When the final products content is lower than 1.79%, don’t need special tagging,once above 1.79% ,please consult with factory technique lab.

Package:25Kgs,200 Kgs drum

Storage: With a shelf time of one year when stored at room temperature in a dark, air-tight, and moisture-proof place.

Transport Mode:

Multipletransportation methods can be selected, Sea Transport, Air Transport, Express Transport and Railway Transport. The transport method will be done according to customers’ request. Our priciple is to delivery the goods reached to customers with shortest time and ecomomic transport mode, safe and fast. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Octylisothiazolinone is also used almost exclusively as a preservative in latex paints, but a small proportion is also used as a preservative in the leather and fur industries. Isothiazolines are also used as slime control agents in the pulp industry and as wood impregnating agents. Low concentrations, mostly <<0.01 %, of isothiazolines are present in a large number of products, which means that the volumes reported are averages with a wide interval. Concentrations are often given as maximum values, which compounds the uncertainty regarding these volumes. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Isothiazolinones containing sulfur atom (S), nitrogen (N), oxygen (O) at 3 position and hydrogen (H) can find application for making broad-spectrum biocides and preservatives such as antiseptic agents, bactericides, slimicides, and fungicides. The biggest application is in paint industry especially marine antifouling agent. They are also used in adhesives, cutting oils, water systems, cosmetics, household goods and wound protectant for pruning cuts. They are also used as pulp and wood impregnating agents as well as in leather, fur and polymer process. It is known to cause allergy and chemical burn if high concentration is used in personal care products and cosmetics. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Common biocides ( antiseptic agents, preservatives, bactericides, slimicides, fungicides) in cosmetics are parabens, isothiazolones, formaldehyde and formaldehyde releasing substances such as quaternium 15, diazolidinyl urea. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

GENERAL DESCRIPTION OF ANTISEPTIC AGENT: Antiseptic agent is a substance which kills or inhibits the growth of disease-causing bacteria and other microorganisms. It is essentially nontoxic to to be applied to the skin or mucous membranes. (Disinfectant including cresol, bleaching powder, and phenol is in general toxic to cells of the body). Common antiseptic agents are Benzalkonium Chloride, Cetrimide, Chlorhexidine, Hexachlorophene, Iodine Compounds, Mercury Compounds (Thimerosol), Alcohol and Hydrogen Peroxide, Hexamine Hippurate, Triclosan, Cetylpyridinium Chloride, And Dequalinium. Other substances which can be used for antiseptic purpose include Boric acid and volatile oils such as Methyl Salicylate. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Hexachlorophene and Benzalkonium Chloride are used primarily in hand or face washes. Benzalkonium Chloride must not be applied to areas which have not been fully rinsed as it is inactivated by organic compounds. Benzalkonium application many include disinfecting instruments and preservativing drugs in low concentration form.

Iodine compounds have the widest spectrum of antiinfectives against bacteria, fungi, spores, protozoa, viruses, and yeasts. Aqueous iodine are less effective than alcoholic solutions, but alcoholic component is drying and irritating to abraided skin. Povidone iodine is convenient to use as it is less irritating, but not as effective. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Chlorhexidine is used as a safe antiseptic or disinfectant to apply to prevent body infection and in oral rinses for treating sore gums and mouth ulcers and preventing plaque on teeth. It is used in the form of acetate, gluconate or hydrochloride, either alone or in combination with others such as cetrimide.

Cetrimide is an antiseptic agent with detergent properties. It has the wide spectrum of antiinfectives against bacteria and fungi. It is used as an ingredient of shampoos for treating seborrhoea and psoriasis. A very dilute solution can be applied topically for the relief of sore gums. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin

Hippuric Acid, an amino acid glycine, is excreted from the body and is used in urinary system drugs. Hexamine hippurates is helpful for preventing and treating infections of the urinary system; it acts by being transformed to formaldehyde.

Triclosan is a very popular antibacterial agent. It is used in hospitals for cleansing and disinfecting the skin of patients and surgeons. It is used in cosmetics, household goods and personal care products. It is also used in plastics and textiles for antibacterial activity purpose.

Cetylpyridinium chloride is used in oral rinses for cleaning mouth and treating minor throat or mouth infections and teething problems.

Dequalinium chloride is antiinfectives against bacteria and fungi. It is used in treating bacterial or fungal infections of mouth and throat.

zotiyazolinon (izotiyazolon ), izotiyazol ile ilgili heterosilik bir kimyasal bileiktir . Dier birçok basit heterosiklete kyasla, kefi oldukça yenidir ve raporlar ilk olarak 1960’larda ortaya çkmtr. Bileiin kendisinin herhangi bir uygulamas yoktur, ancak türevleri yaygn olarak biyositler olarak kullanlmaktadr .

Sentez

Çeitli sentetik yollar bildirilmitir. zotiyazolinonlar tipik olarak endüstriyel ölçekte 3-sülfanilpropanamid türevlerinin halka kapatlmasyla hazrlanr. Bunlar da 3-merkaptopropionik asit yoluyla akrilik asitten üretilir .

zotiyazolinon sentezi

Halka kapatma, tiyol grubunun, nitrojen merkezi tarafndan nükleofilik saldrya maruz kalan reaktif bir türe dönütürülmesini içerir . Bu tipik olarak klorinasyonu [1] veya 3-sülfanilpropanamidin karlk gelen disülfür türlerine oksidasyonunu içerir . Bu reaksiyon koullar, ayn zamanda , istenen ürünü vermek üzere ara izotiyazolidin halkasn da oksitlemektedir .

Uygulamalar

zotiazolinon olan antimikrobik maddeler kontrol için kullanlan bakteriler , mantarlar ve yosunlarn içinde soutma suyu sistemleri , yakt depolama tanklar , kat hamuru ve kat fabrikas su sistemleri, petrol çkarma sistemleri, ahap koruma ve kirlenme önleyici maddeler. ampuanlar ve dier saç bakm ürünleri gibi kiisel bakm ürünlerinde ve belirli boya formülasyonlarnda sklkla kullanlrlar . Genellikle, MIT ve CMIT kombinasyonlar ( Kathon CG olarak bilinir)) veya MIT ve BIT kullanlr.

Örnek bileikler

Metilizotiyazolinon (MIT, MI)

Klorometilizotiyazolinon (CMIT, CMI, MCI)

Benzisothiazolinone (BIT)

Octylisothiazolinone (OIT, OI)

Dichlorooctylisothiazolinone (DCOIT, DCOI)

Butylbenzisothiazolinone (BBIT)

Biyolojik çkarmlar

zotiyazolinonlarn mikroorganizmalar kontrol etme veya öldürme ilevleriyle birlikte istenmeyen etkileri de vardr: OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin, Yüksek su toksisitesine sahiptirler ve baz türevleri dorudan temas veya hava yoluyla ar duyarlla neden olabilir .

3 konumunda kükürt atomu (S), nitrojen (N), oksijen (O) ve hidrojen (H) içeren izotiyazolinonlar, antiseptik maddeler, bakterisitler, ince öldürücüler ve mantar öldürücüler gibi geni spektrumlu biyositler ve koruyucular yapmak için uygulama bulabilir. En büyük uygulama boya endüstrisinde, özellikle denizcilikte zehirli boyadr. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin, Ayrca yaptrclarda, kesme yalarnda, su sistemlerinde, kozmetik ürünlerinde, ev eyalarnda ve budama kesikleri için yara koruyucularda kullanlrlar. Deri, kürk ve polimer ilemlerinin yan sra hamur ve ahap emprenye maddeleri olarak da kullanlrlar. Kiisel bakm ürünlerinde ve kozmetikte yüksek konsantrasyon kullanlmas halinde alerji ve kimyasal yanklara neden olduu bilinmektedir.

Octylisothiazolinone, lateks boyalarda neredeyse sadece bir koruyucu olarak kullanlr, ancak küçük bir ksm da deri ve kürk endüstrisinde koruyucu olarak kullanlr. OIT, KATLON, KATHON IZOTIYAZOLINON, isotiyazolon, isothiazolon, oyit, OYIT, Isothiazolinones, N- OCTYL ISOTHIAZOLINONE, N OKTL ZOTYAZOLNONE, OCTYL ISOTHIAZOLINE, OKTL ZOTYAZOLN, octil izatiyazolin, zotiyazolinler ayrca hamur endüstrisinde ve ahap emprenye maddeleri olarak balçk kontrol maddeleri olarak kullanlr. zotiyazolinlerin düük konsantrasyonlar, çounlukla << 0.01%, çok sayda üründe mevcuttur, bu da rapor edilen hacimlerin geni aralkl ortalamalar olduu anlamna gelir. Konsantrasyonlar genellikle maksimum deerler olarak verilir, bu da bu hacimlerle ilgili belirsizlii birletirir.

2-Octyl-2H-isothiazol-3-one Kimyasal Özellikleri, Kullanm Alanlar, Üretimi

Açklama

Bu izotiyazolon, oktilizotiyazolinon, dier izotiyazolinonlara kyasla nispeten daha az üründe bulunur.

Kimyasal özellikler

Sar kat veya berrak koyu kehribar sv.

Kimyasal özellikler

Açk Sar Ya

Kullanmlar

Mantar ilac. Antimikrobiyal ajan

Kullanmlar

Mantar ilac. Soutma kulesi suyunda, boyalarda, kesme yalarnda, kozmetiklerde ve ampuanda biyosit; deri koruma için.

Kullanmlar

2-n-Oktil-4-izotiyazolin-3-on bir; bakterisit; mantar ilac; soutma kulesi suyundaki biyosit; boyalarda, kesme yalarnda, kozmetiklerde ve ampuanlarda; deri koruma; budama kesimleri için yara koruyucu.

Octylisothiazolinone de hemen hemen sadece lateks boyalarda koruyucu olarak kullanlr, ancak küçük bir ksm da deri ve kürk endüstrisinde koruyucu olarak kullanlr. zotiyazolinler ayrca hamur endüstrisinde ve ahap emprenye maddeleri olarak balçk kontrol maddeleri olarak kullanlr. zotiyazolinlerin düük konsantrasyonlar, çounlukla << 0.01%, çok sayda üründe mevcuttur, bu da rapor edilen hacimlerin geni aralkl ortalamalar olduu anlamna gelir. Konsantrasyonlar genellikle maksimum deerler olarak verilir, bu da bu hacimlerle ilgili belirsizlii birletirir.

kükürt atomu (S), nitrojen (N), oksijen (O) ve hidrojen (H) içeren izotiyazolinonlar, antiseptik maddeler, bakterisitler, ince öldürücüler ve mantar öldürücüler gibi geni spektrumlu biyositler ve koruyucular yapmak için uygulama bulabilir . En büyük uygulama boya endüstrisinde, özellikle denizcilikte zehirli boyadr. Ayrca yaptrclarda, kesme yalarnda, su sistemlerinde, kozmetik ürünlerinde, ev eyalarnda ve budama kesikleri için yara koruyucularda kullanlrlar. Deri, kürk ve polimer ilemlerinin yan sra hamur ve ahap emprenye maddeleri olarak da kullanlrlar. Kiisel bakm ürünlerinde ve kozmetikte yüksek konsantrasyon kullanlmas halinde alerji ve kimyasal yanklara neden olduu bilinmektedir.

OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE),

Kozmetiklerde yaygn olarak kullanlan biyositler (antiseptik maddeler, koruyucular, bakterisitler, sümüksüitler, mantar öldürücüler) parabenler, izotiyazolonlar, formaldehit ve kuaterniyum 15, diazolidinil üre gibi formaldehit salan maddelerdir.

ANTSEPTK AJANIN GENEL AÇIKLAMASI : Antiseptik ajan, hastala neden olan bakteri ve dier mikroorganizmalar öldüren veya büyümesini engelleyen bir maddedir. Deriye veya mukoza zarlarna uygulanmas esasen toksik deildir. (Kresol, aartma tozu ve fenol içeren dezenfektan genel olarak vücut hücreleri için toksiktir). Yaygn antiseptik ajanlar, Benzalkonyum Klorür, Setrimid, Klorheksidin, Heksaklorofen, yot Bileikleri, Cva Bileikleri (Timerosol), Alkol ve Hidrojen Peroksit, Heksamin Hippurat, Triklosan, Setilpiridinyum Klorür ve Dekualinyumdur. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)Antiseptik amaçla kullanlabilen dier maddeler arasnda Borik asit ve Metil Salisilat gibi uçucu yalar bulunur.

Hekzaklorofen ve Benzalkonyum Klorür esas olarak el veya yüz ykamada kullanlr. Benzalkonyum Klorür, organik bileikler tarafndan inaktive edildiinden tam olarak durulanmam alanlara uygulanmamaldr. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)Benzalkonyum uygulamasnn birçou, dezenfekte edici aletler ve düük konsantrasyon formundaki koruyucu ilaçlar içerir.

yot bileikleri, bakterilere, mantarlara, sporlara, protozoa, virüslere ve mayalara kar en geni anti-infektif spektrumuna sahiptir. Sulu iyot, alkollü solüsyonlardan daha az etkilidir, ancak alkollü bileen, tahri olmu cildi kurutur ve tahri eder. Povidon iyot, daha az tahri edici olduu, ancak ayn derecede etkili olmad için kullanm uygundur.

Klorheksidin, vücut enfeksiyonunu önlemek için güvenli bir antiseptik veya dezenfektan olarak ve di etleri ve az ülserlerini tedavi etmek ve dilerde plak oluumunu önlemek için az çalkalamalarnda kullanlr. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Tek bana veya setrimid gibi dierleri ile kombinasyon halinde asetat, glukonat veya hidroklorür formunda kullanlr.

Setrimid, deterjan özelliklerine sahip antiseptik bir ajandr. Bakteri ve mantarlara kar geni bir anti-infektif yelpazesine sahiptir. Sebore ve sedef hastaln tedavi etmek için ampuanlarn bir bileeni olarak kullanlr. Aryan di etlerinin rahatlamas için topikal olarak çok seyreltik bir çözelti uygulanabilir. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Bir amino asit glisin olan Hippurik Asit vücuttan atlr ve üriner sistem ilaçlarnda kullanlr. Heksamin hippuratlar, üriner sistem enfeksiyonlarn önlemek ve tedavi etmek için faydaldr; formaldehite dönütürülerek hareket eder.

Triklosan çok popüler bir antibakteriyel ajandr. Hastanelerde hasta ve cerrahlarn cildinin temizlenmesi ve dezenfekte edilmesinde kullanlr. Kozmetikte, ev eyalarnda ve kiisel bakm ürünlerinde kullanlmaktadr. Plastiklerde ve tekstilde antibakteriyel aktivite amacyla da kullanlmaktadr.

Cetylpyridinium chloride, az temizliinde ve küçük boaz veya az enfeksiyonlarn ve di çkarma problemlerini tedavi etmek için az durulamalarnda kullanlr. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Dequalinium klorür, bakteri ve mantarlara kar anti-infektiftir. Az ve boazda oluan bakteriyel veya fungal enfeksiyonlarn tedavisinde kullanlr. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Tanm

ChEBI: 1,2-tiyazol-3-on olan ve nitrojen üzerinde bir oktil grubu ile ikame edilen (pozisyon 2) 1,2-tiyazol snfnn bir üyesi. Mantar ilac ve antibakteriyel bir ajan olup meyve aaçlarnda pamukçuk ve dier mantar ve bakteri hastalklarnn tedavisinde kullanlr. Artk Avrupa Birlii içinde kullanm için onaylanmad.

Genel açklama

Berrak koyu kehribar sv. Mantar ilac olarak kullanlr. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Hava ve Su Reaksiyonlar

Suda çözünmez.

Reaktivite Profili

2-Octyl-2H-isothiazol-3-one, bir izotiyosiyanat olarak reaksiyona girer. zotiyosiyanatlar, toksik gazlar aça çkarmak için ekzotermik reaksiyona girerek birçok bileik snfyla uyumsuzdur. Aminlerle, aldehitlerle, alkollerle, alkali metallerle, ketonlarla, merkaptanlarla, güçlü oksitleyicilerle, hidrürlerle, fenollerle ve peroksitlerle reaksiyonlar iddetli s salnmna neden olabilir. OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE), OIT (OCTYL ISOTHIAZOLINE)

Yangn tehlikesi

2-Octyl-2H-isothiazol-3-one muhtemelen yancdr.

OIT (N-OCTYL ISOTHIAZOLINONE)

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OIT (N-OCTYL ISOTHIAZOLINONE)

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