TETRASODIUM GLUTAMATE DIACETATE
Tetrasodium glutamate diacetate is a high purity, versatile, and readily biodegradable chelating agent based upon L-glutamic acid, a natural and renewable raw material.
Tetrasodium glutamate diacetate effectively fulfills the same purpose in formulations as EDTA but without the associated health and environmental concerns.
Tetrasodium glutamate diacetate boosts the performance of preservatives, improving shelf life.
CAS Number: 51981-21-6
EC Number: 257-573-7
Chemical Formula: C9H9NNa4O8
Molecular Weight: 351.14 g/mol
Synonyms: C9H13NO8Na4, L-Glutamic acid, N,N-Bis(Carboxymethyl)-, Tetrasodium Salt, L-glutamic acid N,N-diacetic acid, tetrasodium salt, GLDA-Na 4, 51981-21-6, Tetrasodium glutamate diacetate, UNII-5EHL50I4MY, 5EHL50I4MY, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, EINECS 257-573-7, L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4), EC 257-573-7, N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt, GLDA, tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt (ca. 40% in Water), L-Glutamic acid, N,N-bis(carboxymethyl)-, tetrasodium salt, Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, DISSOLVINE GL, CHELEST CMG-40, DTXSID2052158, UZVUJVFQFNHRSY-OUTKXMMCSA-J, MFCD01862262, B2135, Tetrasodium glutamate diacetate [INCI], GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, Q25393000, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, N,N-bis-(Carboxymethyl)-L-glutamic Acid Tetrasodiumn Salt (40% in water), tetrasodium mono((S)-2-(bis(carboxymethyl)amino)-4-carboxybutanoate), Tetrasodium glutamate diacetate, 51981-21-6, Tetrasodium N,N-Bis(carboxymethyl)-L-glutamate, UNII-5EHL50I4MY, 5EHL50I4MY, Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate, EINECS 257-573-7, L-Glutamic acid, N,N-bis(carboxymethyl)-, sodium salt (1:4), EC 257-573-7, N,N-Bis(carboxymethyl)-L-glutamic Acid Tetrasodium Salt, GLDA, tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate, N,N-BIS-(CARBOXYMETHYL)-L-GLUTAMIC ACID TETRASODIUMN SALT, N,N-Bis(carboxymethyl)-L-glutamic acid tetrasodium salt (ca. 40% in Water), Sodium (S)-2-(bis(carboxylatomethyl)amino)pentanedioate, L-Glutamic acid, N,N-bis(carboxymethyl)-, tetrasodium salt, N,N-bis-(Carboxymethyl)-L-glutamic Acid Tetrasodiumn Salt (40% in water), DISSOLVINE GL, CHELEST CMG-40, DTXSID2052158, MFCD01862262, B2135, GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, Q25393000, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, TETRASODIUM (2S)-2-[BIS(CARBOXYLATOMETHYL)AMINO]PENTANEDIOATE, tetrasodium mono((S)-2-(bis(carboxymethyl)amino)-4-carboxybutanoate), C9H13NO8Na4, L-Glutamic acid, N,N-Bis(Carboxymethyl)-, Tetrasodium Salt, CHELEST CMG-40, DISSOLVINE GL, GLUTAMIC ACID N,N-DIACETIC ACID SODIUM SALT, L-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-, SODIUM SALT (1:4), L-GLUTAMIC ACID, N,N-BIS(CARBOXYMETHYL)-, TETRASODIUM SALT, L-GLUTAMIC ACID-N,N-DI(ACETIC ACID) TETRASODIUM SALT, N,N-BIS(CARBOXYMETHYL)GLUTAMIC ACID TETRASODIUM SALT, Tetrasodium glutamate diacetate, TETRASODIUM N,N-BIS(CARBOXYMETHYL)-L-GLUTAMATE, L-Glutamic Acid,N-N Diacetic acid tetra sodium salt; EcoChelate GLDA
Tetrasodium glutamate diacetate is a ‘chelating agent’.
Tetrasodium glutamate diacetate boosts performance of preservatives improving shelf life.
Tetrasodium glutamate diacetate stabilizes the pH value and is effective in wide pH range.
Tetrasodium glutamate diacetate is a versatile, clear, liquid chelating agent and preservative booster.
Derived from plant material, Tetrasodium glutamate diacetate is readily biodegradable and highly soluble across a broad pH range.
Tetrasodium glutamate diacetate effectively fulfills the same purpose in formulations as EDTA but without the associated health and environmental concerns.
Tetrasodium glutamate diacetate acts as a safe alternative, offering effective chelation and preservation properties without compromising on performance.
Tetrasodium glutamate diacetate has a molecular weight of 351.13 and its molecular formula is C9H9NNa4O8.
Tetrasodium glutamate diacetate works to create bonds with unchecked ions that can alter a formula’s appearance, such as preserving soap and keeping it from going bad.
Tetrasodium glutamate diacetate is a high purity, versatile and readily biodegradable chelating agent based upon L-glutamic acid, a natural and renewable raw material.
Tetrasodium glutamate diacetate is a excellent chelating effectiveness controlling metal catalyzed decomposition.
Tetrasodium glutamate diacetate reduces water hardness and prevents precipitation.
Tetrasodium glutamate diacetate boosts performance of preservatives improving shelf life.
Tetrasodium glutamate diacetate stabilizes the pH value and is effective in wide pH range.
Tetrasodium glutamate diacetate does not sensitize human skin.
Completely biodegradable as compared to phosphates and phosphonates.
Tetrasodium glutamate diacetate is effective alternative to EDTA.
Tetrasodium glutamate diacetate is what’s known as a ‘chelating agent’, an ingredient that inactivates metallic ions (charged particles) in product formulations.
Free roaming iron and copper ions in formulations can lead to rapid oxidation, meaning they will spoil quickly.
Tetrasodium glutamate diacetate is a ‘chelating agent’.
Tetrasodium glutamate diacetate is a multi-purpose chelating agent and preservative booster.
Tetrasodium glutamate diacetate serves the same function in formulations as EDTA.
Tetrasodium glutamate diacetate is made from plant material, readily biodegradable, with high solubility over a wide pH range.
Tetrasodium glutamate diacetate is a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium glutamate diacetate is made from plant material, readily biodegradable, with high solubility over a wide pH range.
Tetrasodium glutamate diacetate serves the same function in formulations as EDTA, without the health and environmental concerns.
Tetrasodium glutamate diacetate is a safe synthetic chelating agent with natural origins.
Tetrasodium glutamate diacetate is a nitrilotriacetic acid (NTA)-free and EDTA free chelating agent.
Tetrasodium glutamate diacetate is non-toxic produced from a naturally occurring amino acid.
Tetrasodium glutamate diacetate offers enhanced preservative boosting power.
Tetrasodium glutamate diacetate is recommended for wash-off formulations, wipes, shaving products, fragrances, toiletries, makeup, skin-, sun, baby & oral care products.
This synthetic, Tetrasodium glutamate diacetate, yet non-toxic molecule is a chelating agent.
This means that Tetrasodium glutamate diacetate creates bonds with certain ions that, if left unchecked, could alter the formula’s appearance and even the safety of the product.
In soap, Tetrasodium glutamate diacetate prevents rancidity.
Tetrasodium glutamate diacetate is, therefore, a kind of preservative.
Tetrasodium glutamate diacetate is high purity, versatile and readily biodegradable chelating agent based upon L-glutamic acid, a natural and renewable raw material.
Tetrasodium glutamate diacetate is also known as GLDA chelate.
Tetrasodium glutamate diacetate is a chemical compound that is commonly used in cleaning products.
Tetrasodium glutamate diacetate is a white powder that is soluble in water, and Tetrasodium glutamate diacetate has a number of benefits when used as a cleaning agent.
Tetrasodium glutamate diacetate is effective at removing dirt, grease, and grime from surfaces, and Tetrasodium glutamate diacetate can also help to prevent the growth of mold and mildew.
In addition, Tetrasodium glutamate diacetate is non-toxic and biodegradable, making it safe for use around children and pets.
Tetrasodium glutamate diacetate is an important ingredient in many popular cleaning products, and Tetrasodium glutamate diacetate can be an effective way to keep your home clean and healthy.
The L form of Tetrasodium glutamate diacetate, or GLDA, is based on renewable materials (fermented sugar), functions across a wider pH range, matches or exceeds EDTA in controlling soap scum and is readily biodegradeable.
Tetrasodium glutamate diacetate is also being researched for use as a micronutrient.
Tetrasodium glutamate diacetate is free from genetically modified raw materials and is not irritating to skin or eyes.
Tetrasodium glutamate diacetate is a greener alternative, as it is predominately made from sugar waste material.
The environmental impact (according to ISO 14040) of all strong complexing builders was measured and Tetrasodium glutamate diacetate has the smallest ecological footprint.
Tetrasodium glutamate diacetate is the substituted amine salt that conforms to the formula: C9H9NO3 • 4Na
Uses of Tetrasodium Glutamate Diacetate:
Typical use level of Tetrasodium glutamate diacetate is 0.1-0.5%.
Add Tetrasodium glutamate diacetate at the end of formulation process or to water phase of emulsions.
Tetrasodium glutamate diacetate is used for external use only.
Tetrasodium glutamate diacetate is used in amounts up to 1% to boost the effectiveness of preservatives, allowing for the use of lower amounts than is typical without compromising effectiveness.
Tetrasodium glutamate diacetate is readily biodegradable with a high level of solubility over a wide pH range, thus a greener alternative to many other chelates and phosphates.
Due to the strong chelating ability of calcium and transition metal ions, Tetrasodium glutamate diacetate can prolong the shelf life of many cosmetic products, as well as stabilize and prevent from discoloration.
Tetrasodium glutamate diacetate is used all kinds of cosmetic products like creams, lotions, shampoos, conditioners, makeup products, sunscreen products, hair colorings, powders, personal care wipes.
Tetrasodium glutamate diacetate is a chelating agent and preservative enhancer.
Tetrasodium glutamate diacetate is used in cosmetics mainly because of its ability to boost the effectiveness of other preservatives.
Tetrasodium glutamate diacetate is also used to stabilise the ingredients of cosmetic formulations, preventing the natural discolouration of shampoos and gels.
Tetrasodium glutamate diacetate usually appears as an odorless white powder that is soluble in water, and is used as a multi-purpose, clear, liquid chelating agent and preservative booster.
Tetrasodium glutamate diacetate is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).
Tetrasodium glutamate diacetate usually appears as an odourless white powder that is soluble in water, and is used as a multi-purpose, clear, liquid chelating agent and preservative booster.
Using a chelating agent helps to slow this process, allowing for the creation of products with improved stability and appearance.
This also improves the effectiveness of preservative ingredients, allowing us to use a lower percentage of these, for safer shelf-stable products.
Tetrasodium glutamate diacetate is a chelating agent.
Tetrasodium glutamate diacetate helps maintain pH and removes heavy metal ions from the formulation by binding with them.
Tetrasodium glutamate diacetate helps prevent the formula from oxidizing or otherwise spoiling.
Tetrasodium glutamate diacetate is a safe synthetic chelating agent with natural origins.
Tetrasodium glutamate diacetate is used in amounts up to 1% to boost the effectiveness of preservatives, allowing for the use of lower amounts than is typical without compromising effectiveness.
Tetrasodium glutamate diacetate has many uses from food to personal care products.
Tetrasodium glutamate diacetate is used shampoos Sequestering agent in shampoos & cleaners to improve stability.
Tetrasodium glutamate diacetate is used to prevent metal ion impurities from modifying colors of dyed products.
Tetrasodium glutamate diacetate is used as preservative in some foods to prevent catalytic oxidative discoloration.
Tetrasodium glutamate diacetate is used to remove water hardness in laundry applications.
Tetrasodium glutamate diacetate is used to prevent scale formation in boilers due to water hardness.
Tetrasodium glutamate diacetate is used in complexometric titrations and analysis of water hardness.
Tetrasodium glutamate diacetate is a naturally and sustainably produced sequestrant derived from the Amino Acid Glutamic acid.
Tetrasodium glutamate diacetate can be used to replace EDTA acid and EDTA salts such as Tetrasodium EDTA in a 1:1 ratio.
Tetrasodium glutamate diacetate is an alkaline sequestering agent it binds up and makes inert impurities such as metal ions of iron, magnesium and calcium, and prevents them from interacting with other ingredients.
Tetrasodium glutamate diacetate is a chelating agent created from natural, biodegradable and renewable raw materials.
Tetrasodium glutamate diacetate is suitable to be used in personal care and cosmetics
Stable over a wide pH range and highly soluble, Tetrasodium glutamate diacetate works to create bonds with unchecked ions that can alter a formula’s appearance.
For example, this can preserve soap and prevent Tetrasodium glutamate diacetate from going bad.
Tetrasodium glutamate diacetate can also function as a preservative enhancer.
Tetrasodium glutamate diacetate inactivates metallic ions (charged particles) in product formulations, hence acting as is a chelating agent.
Free roaming iron and copper ions in formulations can lead to rapid oxidation.
Using a chelating agent, Tetrasodium glutamate diacetate, helps to slow this process, allowing for the creation of products with improved stability and appearance.
This also improves the effectiveness of preservative ingredients, allowing us to use a lower percentage of these, for safer shelf-stable products.
Tetrasodium glutamate diacetate is often found in sunscreen, facial cleanser, shampoo, makeup, lotion, cleansing wipes, bar soap, and other cleaning products.
Cleaning:
Tetrasodium glutamate diacetate is a multi-functional ingredient that can be used in a variety of cleaning products.
Tetrasodium glutamate diacetate is an effective degreaser and can be used to remove oils and greases from surfaces.
Tetrasodium glutamate diacetate is also a powerful dispersant, which means it can be used to break up stubborn dirt and grime.
In addition, Tetrasodium glutamate diacetate is a great sanitizer and can help to kill bacteria and viruses.
As a result, Tetrasodium glutamate diacetate is an ideal ingredient for use in a wide range of cleaning products.
Personal Care:
Tetrasodium glutamate diacetate is a multi-functional ingredient used in personal care products.
Tetrasodium glutamate diacetate has excellent solubility in water and good binding properties.
Tetrasodium glutamate diacetate can be used as a surfactant, emulsifier, conditioner, or suspender.
Tetrasodium glutamate diacetate is also an effective chelating agent that helps to improve the performance of other ingredients in a formulation.
Tetrasodium glutamate diacetate is compatible with most cosmetic bases and can be used in a wide variety of products, including shampoos, conditioners, body washes, and lotions.
When used at the recommended concentration, Tetrasodium glutamate diacetate is safe and effective for both leave-on and rinse-off products.
Tetrasodium glutamate diacetate is an excellent choice for personal care formulations that require high performance and reliability.
Features of Tetrasodium Glutamate Diacetate:
High solubility under wide pH:
Tetrasodium glutamate diacetate has good solubility in strong acid to high alkali systems, and has better advantages for formulating high active ingredients and low water content formulation systems.
Good stability under high temperature:
By thermogravimetric analysis, Tetrasodium glutamate diacetate is tested at 170°C for 6 hours or at 150°C for a week.
Tetrasodium glutamate diacetate has no decomposition and is extremely stable.
Compared with other chelating agent products at 100°C, Tetrasodium glutamate diacetate has the best performance.
Strong chelating ability:
Tetrasodium glutamate diacetate has a good effect on all kinds of difficult-to-clean calcium scales or difficult-to-clean equipment.
Has the effect of antiseptic and synergistic:
Because Tetrasodium glutamate diacetate has natural amino acid components, Tetrasodium glutamate diacetate has a stronger binding ability with animal cell walls, and thus play a role in antiseptic and synergistic.
After experiments, we found that Tetrasodium glutamate diacetate has obvious antiseptic and sterilization synergies in many fungicides, which can save 20%-80% of the usage.
Benefits of Tetrasodium Glutamate Diacetate:
Tetrasodium glutamate diacetate works as a stabilizer in cosmetic formulations to preventing the natural discoloration of shampoos and gels.
Tetrasodium glutamate diacetate is used to enhance and preservative the formulation’s ingredients and also acts as a heavy metal chelating agent.
Other Benefits:
Excellent chelating effectiveness controlling metal catalyzed decomposition
Reduces water hardness and prevents precipitations
Boosts performance of preservatives improving shelf life
Stabilizes the pH value and is effective in wide pH range
Does not sensitize human skin
Completely biodegradable as compared to phosphates and phosphonates
Effective alternative to EDTA
Origin of Tetrasodium Glutamate Diacetate:
Tetrasodium glutamate diacetate is an organic salt synthesized from glutamic acid (an amino acid abundant in nature).
Functions of Tetrasodium Glutamate Diacetate:
Chelating:
Tetrasodium glutamate diacetate reacts and forms complexes with metal ions that could affect the stability and / or appearance of cosmetic products
Tetrasodium glutamate diacetate binds metal ions which could negatively affect the stability and / or appearance of cosmetics
Production of Tetrasodium Glutamate Diacetate:
The production of Tetrasodium glutamate diacetate involves several chemical steps:
Glutamic Acid:
Glutamic acid, an amino acid derived from vegetable sources like sugar beets or wheat, serves as the starting material.
Esterification:
Tetrasodium glutamate diacetate undergoes esterification to produce a compound known as glutamic acid diethyl ester.
Hydrolysis:
Hydrolysis of the ester yields the final product, Glutamic Acid Diacetic Acid or GLDA.
The resulting Tetrasodium glutamate diacetate is then purified and formulated into the desired products or applications.
In conclusion, Tetrasodium glutamate diacetate is a versatile chelating agent used in various industries due to its ability to bind to metal ions and prevent issues such as scaling and spoilage.
Tetrasodium glutamate diacetate’s biodegradability, compatibility, and environmentally friendly nature make Tetrasodium glutamate diacetate a valuable ingredient in cleaning products, personal care items, and the food and beverage industry.
Understanding Tetrasodium glutamate diacetate’s benefits and production process underscores its significance in modern manufacturing and product development.
Alternatives of Tetrasodium Glutamate Diacetate:
Trisodium Ethylenediamine Disuccinate
EDTA
Safety Profile of Tetrasodium Glutamate Diacetate:
The safety of Tetrasodium glutamate diacetate was assessed by the Expert Panel for Cosmetic Ingredient Safety (formerly called the Cosmetic Ingredient Review Expert Panel) in 2021.
The Expert Panel concluded that Tetrasodium glutamate diacetate was safe as used in the present practices of use and concentration in cosmetics and personal care products.
The Expert Panel noted Tetrasodium glutamate diacetate is slowly absorbed through the gastrointestinal tract and skin absorption is likely to be even slower.
Handling And Storage of Tetrasodium Glutamate Diacetate:
Conditions for safe storage, including any incompatibilities:
Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Stability And Reactivity of Tetrasodium Glutamate Diacetate:
Reactivity:
No data available
Chemical stability:
Stable under recommended storage conditions.
Possibility of hazardous reactions:
No data available
Conditions to avoid:
No data available
First Aid Measures of Tetrasodium Glutamate Diacetate:
If inhaled:
If breathed in, move person into fresh air.
In case of skin contact:
Wash off with soap and plenty of water.
In case of eye contact:
Flush eyes with water as a precaution.
If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Indication of any immediate medical attention and special treatment needed:
No data available
Fire Fighting Measures of Tetrasodium Glutamate Diacetate:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Further information:
No data available
Accidental Release Measures of Tetrasodium Glutamate Diacetate:
Environmental precautions:
Do not let product enter drains.
Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.
Exposure Controls/Personal Protection of Tetrasodium Glutamate Diacetate:
Personal protective equipment:
Eye/face protection:
Use equipment for eye protection.
Skin protection:
Handle with gloves.
Wash and dry hands.
Body Protection:
Impervious clothing.
Respiratory protection:
Respiratory protection not required.
Control of environmental exposure:
Do not let product enter drains.
Identifiers of Tetrasodium Glutamate Diacetate:
CAS Number: 51981-21-6
Chemical Formula: C9H9NNa4O8
Molecular Weight: 351.14 g/mol
EINECS Number: 257-573-7
UNII: QF6M1M3U5H
InChI Key: XZHKHCHEVDMAES-UHFFFAOYSA-J
CAS Number: 51981-21-6
EC Number: 257-573-7
Chem/IUPAC Name: Tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioatee
Molecular formula: C9H9NO8Na4
Properties of Tetrasodium Glutamate Diacetate:
Appearance: Light yellow viscous liquid
Content /%: ≥47
pH value: ≥8.5
Density(20℃) g/cm3: ≥1.20
Boiling Point: 105-110°C
Specific Gravity: 1.15-1.45
pH: 11-12 (in 1% water)
Solubility: Completely miscible in water
Slightly soluble in methanol/ethanol
Viscosity: 75-275 mPa.s @ 25°C
Molecular Weight: 351.13 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 5
Exact Mass: 350.99189337 g/mol
Monoisotopic Mass: 350.99189337 g/mol
Topological Polar Surface Area: 164Ų
Formal Charge: 0
Complexity: 314
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes
Boiling Point: 105-110°C
Specific Gravity: 1.15-1.45
pH: 11-12 (in 1% water)
Solubility: Completely miscible in water,
Slightly soluble in methanol/ethanol
Viscosity: 75-275 mPa.s @ 25°C
Molecular Weight: 351.13 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 5
Exact Mass: 350.99189337 g/mol
Monoisotopic Mass: 350.99189337 g/mol
Topological Polar Surface Area: 164Ų
Heavy Atom Count: 22
Complexity: 314