DMDM HYDANTOIN
Synonym(s): DMDM HYDANTOIN, 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYL- 2,4-IMIDAZOLIDINEDIONE; 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYLIMIDAZOLIDINE-2,4-DIONE;
1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYLIMIDAZOLIDINE-2,4-DIONE (+) ; 1,3-DIHYDROXYMETHYL-5,5 DIMETHYLHYDANTOIN; 1,3-DIMETHYLOL-5,5-DIMETHYL HYDANTOIN;
2,4-IMIDAZOLIDINEDIONE, 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYL-; 2,4IMIDAZOLIDINEDIONE, 1,3BIS (HYDROXYMETHYL) 5,5DIMETHYL;
1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYLHYDANTOIN; 2,4-IMIDAZOLIDINEDIONE, 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYL- (9CI) ; DANTOIN DMDMH 55;
DIMETHYLOL-5,5-DIMETHYLHYDANTOIN
Function(s) of DMDM HYDANTOIN: Preservative
About DMDM HYDANTOIN (FORMALDEHYDE RELEASER): DMDM hydantoin is an antimicrobial formaldehyde releaser preservative. People exposed to such formaldehyde-releasing
ingredients may develop a formaldehyde allergy or an allergy to the ingredient itself and its decomposition products. In the U.S., approximately 20% of cosmetics
and personal care products contain a formaldehyde-releaser and the frequency of contact allergy to these ingredients is much higher among Americans compared to
studies in Europe.
Allergies/immunotoxicity of DMDM HYDANTOIN:
Known human immune toxicant or allergen
Human skin toxicant or allergen – strong evidence
Limited evidence of immune system toxicity or allergies
Use restrictions:
Restricted in cosmetics (recommendations or requirements) – use, concentration, or manufacturing restrictions – Japan – restricted
for use in some types of cosmetics (concentration limit)
Restricted in cosmetics (recommendations or requirements) – use, concentration, or manufacturing restrictions – Japan – prohibited
for use in some types of cosmetics
Cancer:
Cancer – limited evidence
Irritation (skin, eyes, or lungs) of DMDM HYDANTOIN:
Human irritant – strong evidence (only for products for use around the eyes, on the skin, or may be aerosolized (airborne))
Ecotoxicology of DMDM HYDANTOIN:
Not suspected to be an environmental toxin
Persistence and bioaccumulation of DMDM HYDANTOIN:
Not suspected to be persistent
Not suspected to be bioaccumulative
Organ system toxicity (non-reproductive) of DMDM HYDANTOIN:
Classified as not expected to be potentially toxic or harmful
Chemical release concerns of DMDM HYDANTOIN:
FORMALDEHYDE
DMDM HYDANTOIN’in levleri: Koruyucu
DMDM Hakknda HYDANTOIN (FORMALDEHYDE RELEASER): DMDM hidantoin, antimikrobiyal bir formaldehit serbest brakc koruyucudr. Bu tür formaldehitle serbest braklan maruz kalanlar
Bileenler bir formaldehit alerjisi veya bileenin kendisi ve ayrma ürünlerine kar bir alerji gelitirebilir. ABD’de, kozmetik ürünlerinin yaklak% 20’si
Ve kiisel bakm ürünleri formaldehit salc içerir ve bu katk maddelerine kontak alerjisi skl Amerikallar arasnda Avrupa’daki çalmalara kyasla çok daha yüksektir.
DMDM HYDANTOIN için alerji / immüno-toksisite:
Bilinen insan baklk toksik veya alerjen
nsan cildi toksik veya alerjen – güçlü kant
Snrl baklk sistemi toksisitesi veya alerji kantlar
Kullanm kstlamalar:
Kozmetikte kstl (tavsiyeler veya gereklilikler) – kullanm, konsantrasyon veya üretim kstlamalar – Japonya – snrl
Baz kozmetik tiplerinde (konsantrasyon limiti)
Kozmetikte kstlanmtr (tavsiyeler veya gereklilikler) – Kullanm, konsantrasyon veya üretim kstlamalar – Japonya – yasaktr
Baz kozmetik tipleri için
Kanser:
Kanserle snrl kant
DMDM HYDANTOIN tahrii (cilt, göz veya akcierler):
nsan tahri edici – güçlü kantlar (yalnzca göz çevresindeki ciltteki ürünler için veya aerosol haline getirilmi (hava yoluyla bulaabilen) ürünler için)
DMDM’nin Ekotoksikolojisi HYDANTOIN:
Çevresel bir toksin olduundan üphelenilmez
DMDM HDANTOIN’n Direnç ve Biyoakümülasyon:
Kalc olduundan üphelenilmez
Biyoakümülatif olduundan üphelenilmez
DMDM HYDANTOIN’n organ sistemi toksisitesi (üreme d):
Potansiyel olarak zehirli veya zararl olmas beklenmediine göre snflandrlmtr.
DMDM HYDANTOIN’in kimyasal salm endieleri:
Kimyasal:
FORMALDEHT