PEG 300 (POLYETHYLENE GLYCOL 300)
PEG 300 (POLYETHYLENE GLYCOL 300)
CAS No. : 25322-68-3
EC No. : 500-038-2
Synonyms:
ETHYLENE GLYCOL; 1,2-ethanediol; Ethane-1,2-diol; 107-21-1; glycol; monoethylene glycol; 1,2-Dihydroxyethane; 2-hydroxyethanol; Glycol alcohol; Ethylene alcohol; polyethylene glycol; Macrogol; Fridex; Tescol; Ethylene dihydrate; Norkool; Macrogol 400 BPC; Dowtherm SR 1; ethanediol; Zerex; Ucar 17; Lutrol-9; Polyethylene glycol 200; ethyleneglycol; Aethylenglykol; Glycol, ethylene-; 1,2-Ethandiol; Glycols, polyethylene; Caswell No. 441; Ethylenglycol; Aethylenglykol [German]; ethylen glycol; ethylene-glycol; Lutrol; PEG 400; Polyethylene glycol 600; 146AR; Polyethylene glycol 1000; UNII-FC72KVT52F; Lutrol 9; Carbowax 20; MFCD00002885; NSC 93876; Carbowax 300; Carbowax 400; CCRIS 3744; Carbowax 1000; Dowtherm 4000; 1,2-ethylene glycol; 1,2-dihydroxy ethane; Ethylene glycol polymer; HSDB 5012; NCI-C00920; HOCH2CH2OH; Union Carbide XL 54 Type I De-icing Fluid; PEG 3350; EINECS 203-473-3; M.e.g.; Ethylene glycol homopolymer; Polyethylene Glycol 4000; EPA Pesticide Chemical Code 042203; 1,2-Ethanediol homopolymer; FC72KVT52F; AI3-03050; PEG; DTXSID8020597; CHEBI:30742; PEG 4000; 1, 2-Ethanediol; DuPont Zonyl FSO Fluorinated Surfactants; alpha-Hydro-omega-hydroxypoly(oxyethylene); DSSTox_CID_597; Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-; Poly(oxy-1,2-ethanediyl, alpha-hydro-omega-hydroxy-; F0001-0142; 004143F9-240E-472F-9D5A-B1B13BBA2A18; Ethylene glycol, United States Pharmacopeia (USP) Reference Standard; Ethylene glycol, Pharmaceutical Secondary Standard; Certified Reference Material; Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.; Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.; ethylene glycol;1,2-ethanediol;ethane-1,2-diol;glycolethylene glycol;ethanediol;ethylene glycol 1,2-ethanediol ethane-1,2-diol glycolethylene glycol ethanediol
EN
PEG 300 Applications
PEG 300 Application Polyethylene glycol 1500 for synthesis. CAS 25322-68-3, pH 4 – 7 (100 g/l, H₂O, 20 °C).
PEG 300 Physicochemical Information
PEG 300 Boiling point >200 °C (1013 hPa)
PEG 300 Density 1.2 g/cm3 (20 °C)
PEG 300 Flash point 240 °C
PEG 300 Ignition temperature 420 °C
PEG 300 Melting Point 43 – 49 °C
PEG 300 pH value 4 – 7 (100 g/l, H₂O, 20 °C)
PEG 300 Vapor pressure <0.01 hPa (20 °C)
PEG 300 Bulk density 400 – 500 kg/m3
PEG 300 Solubility 650 g/l
PEG 300 Toxicological Information
PEG 300 LD 50 oral LD50 Rat 28000 mg/kg
PEG 300 LD 50 dermal LD50 Rabbit > 20000 mg/kg
PEG 300 Safety Information according to GHS
PEG 300 Storage class 10 Combustible liquids
PEG 300 WGK WGK 1 slightly hazardous to water
PEG 300 Disposal 3
PEG 300 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
PEG 300 Storage and Shipping Information
PEG 300 Storage Store below +30°C.
PEG 300 Transport Information
PEG 300 Declaration (railroad and road) ADR, RID Kein Gefahrgut
PEG 300 Declaration (transport by air) IATA-DGR No Dangerous Good
PEG 300 Declaration (transport by sea) IMDG-Code No Dangerous Good
PEG 300 Specifications
PEG 300 Melting range (lower value) ≥ 43 °C
PEG 300 Melting range (upper value) ≤ 49 °C
PEG 300 Hydroxyl value 70 – 80
PEG 300 Average molecular mass 1400 – 1600
PEG 300 Identity (IR) passes test
Activated PEG 300s (for conjugation to biologics)
PEG 300-PLA or PEG 300-PLGA (for nanoparticle formulations of drugs)
Linear and branched functionalized polyethylene imines and other polyimines (for oligo-nucleotide binding and delivery)
PEG 300-pAsp / PEG 300-pGlu (for oligo-nucleotide binding and delivery)
Hyperbranched polyglycerols (for drug delivery and protein formulation)
Other polymers for nanoparticle formation (drug delivery)
Poly(ethylene glycol) (PEG 300) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG 300 and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG 300 also interacts with cell membrane, thereby allowing cell fusion.Polyethylene Glycol 1500 (PEG 300-1500) has been used to mediate cell fusion.PEG 300 is a polymer of ethylene oxide with an average molecular weight of 1500. This polymeric material is an excellent solubiliser and can be used in a wide variety of home care and I&I applications.Polyethylene glycol. PEG- 1500 by Dynamic International is a surfactant. It is available in the form of milky white solid. PEG- 1500 is used in cream and shampoo base material.Crystallization grade Polyethylene glycol 1500(PEG 300) for formulating screens or for optimization.PEG 300 Eye contact Unlikely to cause eye irritation in man.PEG 300 Skin contact Unlikely to cause skin irritation in man.PEG 300 Inhalation This material may cause irritation following inhalation.PEG 300 Ingestion Will cause irritation of the gastrointestinal tract.Low oral toxicity, but ingestion may cause irritation of the gastrointestinal tract.PEG 300 Eye contact Irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.PEG 300 Skin contact Remove contaminated clothing. Wash skin with soap and water. If symptoms develop, obtain medical attention.PEG 300 Inhalation Remove patient from exposure. Obtain medical attention if ill effects occur.PEG 300 Ingestion Do not induce vomiting. Wash out mouth with water and give 200-300 ml (half a pint) of water to drink. Obtain medical attention if ill effects occur.PEG 300 Further Medical Treatment Symptomatic treatment and supportive therapy as indicated.PEG 300 Extinguishing Media Water fog, alcohol foam, carbon dioxide, dry chemical.PEG 300 Unsuitable Extinguishing Media None known.PEG 300 Special fire-fighting protective equipment A self contained breathing apparatus and suitable protective clothing must be worn in fire conditions.PEG 300 Fire and explosion hazards Combustible but not readily ignited.
PEG 300 Colour white
PEG 300 Form solid
PEG 300 Odour mild
PEG 300 pH approx 5 – 7 5% In water
PEG 300 Boiling point/boiling range (°C) No data.
PEG 300 Flash Point (ºC) > 260 (open cup)
PEG 300 Autoignition Temperature (ºC) approx 420
PEG 300 Flammable Limits No data.
PEG 300 Explosive Properties No data.
PEG 300 Oxidising Properties No data.
PEG 300 Vapour Density No data.
PEG 300 Solubility in water soluble
PEG 300 Solubility in other ingredients Soluble in many organic solvents, insoluble in:, aliphatic hydrocarbons
PEG 300 Partition Coefficient No data.
PEG 300 Dynamic viscosity (mPa.s) approx 30 @99°C
PEG 300 Density (g/ml) 1.208 @ 20 °C
PEG 300 Stability Stable under normal conditions.
PEG 300 Materials to avoid Strong oxidising agents.
PEG 300 Conditions to avoid None known
PEG 300 Hazardous decomposition products None known
PEG 300 Hazardous polymerisation Will not occur
TR
PEG 300 Uygulamalar
PEG 300 Uygulama Polietilen glikol 1500 sentez için. CAS 25322-68-3, pH 4-7 (100 g / l, H₂O, 20 ° C).
PEG 300 Fizikokimyasal Bilgiler
PEG 300 Kaynama noktas> 200 ° C (1013 hPa)
PEG 300 Younluk 1.2 g / cm3 (20 ° C)
PEG 300 Parlama noktas 240 ° C
PEG 300 Tutuma scakl 420 ° C
PEG 300 Erime Noktas 43-49 ° C
PEG 300 pH deeri 4-7 (100 g / l, H₂O, 20 ° C)
PEG 300 Buhar basnc <0.01 hPa (20 ° C)
PEG 300 Yn younluu 400 – 500 kg / m3
PEG 300 Çözünürlük 650 g / l
PEG 300 Toksikolojik Bilgi
PEG 300 LD 50 oral LD50 Sçan 28000 mg / kg
PEG 300 LD 50 dermal LD50 Tavan> 20000 mg / kg
GHS’ye göre PEG 300 Güvenlik Bilgileri
PEG 300 Depolama snf 10 Yanc svlar
PEG 300 WGK WGK 1 su için hafif tehlikeli
PEG 300 mha 3
PEG 300 Nispeten reaktif olmayan organik reaktifler A kabnda toplanmaldr. Halojenlenmise, bunlar kap B’de toplanmaldr. Kat kalntlar için kap C’yi kullann.
PEG 300 Saklama ve Nakliye Bilgileri
PEG 300 Depolama + 30 ° C’nin altnda saklayn.
PEG 300 Tama Bilgileri
PEG 300 Beyan (demiryolu ve karayolu) ADR, RID Kein Gefahrgut
PEG 300 Beyan (hava yoluyla tama) IATA-DGR Tehlikeli Madde Yok
PEG 300 Beyan (deniz yoluyla tama) IMDG-Kodu Tehlikeli Mal Yok
PEG 300 Özellikleri
PEG 300 Erime aral (düük deer) ≥ 43 ° C
PEG 300 Erime aral (üst deer) ≤ 49 ° C
PEG 300 Hidroksil deeri 70 – 80
PEG 300 Ortalama moleküler kütle 1400 – 1600
PEG 300 Kimlik (IR) testi geçti
Aktifletirilmi PEG 300’ler (biyolojikle elenik için)
PEG 300-PLA veya PEG 300-PLGA (nanopartikül ilaç formülasyonlar için)
Dorusal ve dall ilevselletirilmi polietilen iminler ve dier poliiminler (oligo-nükleotid balanmas ve datm için)
PEG 300-pAsp / PEG 300-pGlu (oligo-nükleotid balanmas ve datm için)
Ar dallanm poligliseroller (ilaç datm ve protein formülasyonu için)
Nanopartikül oluumu için dier polimerler (ilaç datm)
Poli (etilen glikol) (PEG 300) iyonik olmayan hidrofilik bir polimerdir ve farkl moleküler arlklarda mevcuttur. Proteinlerin ve nükleik asitlerin saflatrlmasna ve kristal büyümesine yardmc olur. PEG 300 ve dekstran birlikte biyolojik materyallerin saflatrlmas için gerekli olan sulu polimer iki fazl sistem ile sonuçlanr. PEG 300 ayrca hücre zar ile etkileime girerek hücre füzyonuna izin verir. Hücre füzyonuna araclk etmek için Polietilen Glikol 1500 (PEG 300-1500) kullanlmtr. PEG 300, ortalama molekül arl 1500 olan bir etilen oksit polimeridir. Bu polimerik malzeme mükemmel bir çözündürücüdür ve çok çeitli evde bakm ve I&I uygulamalarnda kullanlabilir. Polietilen glikol. Dynamic International tarafndan sunulan PEG-1500 bir yüzey aktif maddedir. Süt beyaz kat formda mevcuttur. PEG-1500, krem ve ampuan esasl malzemede kullanlr. Ekranlarn formüle edilmesi veya optimizasyon için kristalizasyon snf Polietilen glikol 1500 (PEG 300) PEG 300 Göz temas nsanlarda göz tahriine neden olmas olas deildir PEG 300 Cilt temas man.PEG 300 Soluma Bu malzeme solunduunda tahrie neden olabilir. PEG 300 Yutma Gastrointestinal sistemde tahrie neden olur. Az yoluyla düük toksisite, ancak yutulmas mide-barsak yolunda tahrie neden olabilir. PEG 300 Göz temas Göz ykama solüsyonu veya temiz su ile ykayn, göz kapaklarn en az 10 dakika açk tutarak. Tbbi yardm aln PEG 300 Deri temas Kirlenmi giysileri çkarn. Cildi sabun ve suyla ykayn. Semptomlar geliirse, tbbi yardm aln. PEG 300 Soluma Hastay maruziyetten çkarn. Hastalk etkileri meydana gelirse tbbi yardm aln. PEG 300 Yutma Kusturmaya çalmayn. Az suyla çalkalayn ve içmesi için 200-300 ml (yarm litre) su verin. Hastalk etkileri oluursa tbbi yardm aln PEG 300 leri Tbbi Tedavi Belirtildii gibi semptomatik tedavi ve destekleyici tedavi PEG 300 Söndürme Ortam Su sisi, alkol köpüü, karbondioksit, kuru kimyasal PEG 300 Uygun Olmayan Söndürme Ortam Bilinmiyor. PEG 300 Özel yangn- koruyucu ekipmanla mücadele Yangn koullarnda bamsz bir solunum aparat ve uygun koruyucu giysi giyilmelidir. PEG 300 Yangn ve patlama tehlikeleri Yancdr ancak hemen tutumaz.
PEG 300 Renk beyaz
PEG 300 Kat form
PEG 300 Koku hafif
PEG 300 pH yaklak% 5-7% 5 Suda
PEG 300 Kaynama noktas / kaynama aral (° C) Veri yok.
PEG 300 Parlama Noktas (ºC)> 260 (açk kap)
PEG 300 Kendiliinden Tutuma Scakl (ºC) yaklak 420
PEG 300 Alev Alma Snrlar Veri yok.
PEG 300 Patlayc Özellikler Veri yok.
PEG 300 Oksitleyici Özellikler Veri yok.
PEG 300 Buhar Younluu Veri yok.
PEG 300 Suda çözünebilirlik
PEG 300 Dier bileenlerde çözünürlük Birçok organik çözücüde çözünür, uralarda çözünmez :, alifatik hidrokarbonlar
PEG 300 Bölme Katsays Veri yok.
PEG 300 Dinamik viskozite (mPa.s) yaklak 30 @ 99 ° C
PEG 300 Younluk (g / ml) 1.208 @ 20 ° C
PEG 300 Kararllk Normal koullar altnda kararldr.
PEG 300 Kullanlacak malzemelerid Güçlü oksitleyici maddeler.
PEG 300 Kaçnlmas gereken koullar Bilinmiyor
PEG 300 Tehlikeli bozunma ürünleri Bilinmiyor
PEG 300 Tehlikeli polimerizasyon Meydana gelmeyecek