TRIS(2-BUTOXYETHYL) PHOSPHATE

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TRIS(2-BUTOXYETHYL) PHOSPHATE

Tris(2-butoxyethyl) phosphate is primarily used as a flame retardant and plasticizer in various applications, including polyurethane rubber, cellulose, and polyvinyl alcohol.

Tris(2-butoxyethyl) phosphate is a slightly yellow, viscous liquid that serves as a multifunctional additive, enhancing the flame retardancy and flexibility of polymers.

Tris(2-butoxyethyl) phosphate is employed in floor finishes, water-based adhesives, and as a plasticizer for rubbers and resins, with good low-temperature characteristics.

CAS Number: 78-51-3

EC Number: 201-122-9

Molecular Formula: C18H39O7P

Molecular Weight: 398.5 g/mol

Synonyms: Tris(2-butoxyethyl) phosphate, 78-51-3, TRI(2-BUTOXYETHYL) PHOSPHATE, TBEP, Tributoxyethyl phosphate, Phosflex T-bep, Tris(butoxyethyl) phosphate, tris(2-butoxyethyl)phosphate, Ethanol, 2-butoxy-, phosphate (3:1), Tri(butoxyethyl) phosphate, Kronitex KP-140, Tributyl cellosolve phosphate, KP 140, Phosphoric acid, tributoxyethyl ester, Phosphoric acid, tris(2-butoxyethyl) ester, Tri(2-butoxyethanol)phosphate, NSC 4839, Tris-(2-butoxyethyl)fosfat, UNII-RYA6940G86, Ethanol, 2-butoxy-, 1,1′,1”-phosphate, tributoxy ethyl phosphate, 2-Butoxyethanol phosphate, Tris(butoxyethyl)phosphate, CHEBI:35038, RYA6940G86, tris[2-(butyloxy)ethyl] phosphate, TBEP;KP 140;Hostaphat B 310, Phosphoric acid, tri-(2-butoxyethyl) ester, DSSTox_CID_1758, DSSTox_RID_76309, Ethanol, phosphate (3:1), DSSTox_GSID_21758, WLN: 4O2OPO&O2O4&O2O4, 2-Butoxyethanol, phosphate, CAS-78-51-3, Phosphoric acid, tri(butoxyethyl) ester, CCRIS 5942, Tri(2-butoxyethanol) phosphate, HSDB 2564, 2-Butoxyethanol phosphate (3:1), EINECS 201-122-9, Tris-(2-butoxyethyl)fosfat [Czech], Tris(2-butoxyethyl) phosphate,C18H39O7P,78-51-3, BRN 1716010, tris-2-butoxyethyl phosphate, AI3-04596, C18H39O7P, Amgard TBEP, MFCD00009456, Phosphoric Acid Tris(2-butoxyethyl) Ester, EC 201-122-9, tris-(2-butoxyethyl)phosphate, 2-Butoxy-ethanol phosphate (3:1), Phosphoric acid tris(2-butoxyethyl), Tris(2-butoxyethyl) phosphate, 94%, TRI-(2-BUTOXYETHYL)-PHOSPHATE, Tris(2-butoxyethyl)ester phosphoric acid, Phosphoric acid tris(2-n-butoxyethyl)ester, Phosphoric acid tris(2-n-butoxyethyl) ester, A915093, Tris(2-butoxyethyl) phosphate, analytical standard, W-104277, Q27116378, 2-butoxy, 2-Butoxy-ethanol phosphate (3:1), 2-Butoxy-ethanolphosphate(3:1), 2-butoxy-ethanophosphate(3:1), Amgard TBEP, Ethanol, 2-butoxy-, phosphate (3:1), tri(butoxyethyl), Tri(butylcellosolve)phosphate, Tributyl cellosolve phosphate, tributylcellosolvephosphate, Tris(2-butoxyethyl)ester phosphoric acid, Tris-(2-butoxyethyl)fosfat, Tris2-butoxyethyl, TBXP, TRIS(BUTOXYETHYL) PHOSPHATE 98%, TRIS(BUTOXYETHYL)PHOSPHATE (TBEP), Tris-(2-butoxyethyl)-phosphat, Tributoxylethyl Phosphate, Tris(2-butoxyethyl) phosphate | TBEP, O,O,O-Tris(2-butoxyethyl)phosphate, Tri(2-butoxyethyl) phospha, Tris(3-butoxyethyl) phosphate, Phosphoric acid tris(2-butoxyethyl), TRIS(2-BUTOXYETHANOL)PHOSPHATE, Tris(2-butoxyethyl) phosphate,95%, Tributoxyethyl Phosphate (TBEP), PHOSPHORIC ACID TRIS(2-N-BUTOXYETHYL) ESTER, PHOSPHORIC ACID TRIS(2-BUTOXYETHYL) ESTER, TBEP, TRI(BUTOXYETHYL)PHOSPHATE, TRIS(BUTOXYETHYL) PHOSPHATE, TRIS(2-BUTOXYETHYL) PHOSPHATE, ethanol,2-butoxy-,phosphate(3:1), KP 140, kp140, KP-140, Kronitex kp-140, kronitexkp-140, Phosflex T-bep, phosflext-bep, Phosphoric Acid, tributoxyethyl ester, Tri(2-butoxyethanol)phosphate, Tri(2-butoxyethyl) phosphate, tri(2-butoxyethyl)phosphate, 2-BUTOXYETHANOL PHOSPHATE, Plasticizer TBEP, Ethanol, 2-butoxy-, 1,1′,1”-phosphate, Tris(2-butoxyethyl)Phosphate>, tris(2-Butoxyethyl) Phosphate (TBEP) @100 μg/mL in Toluene, Tri-butoxyethyl phosphate@1000 μg/mL in Hexane, Tris(2-butoxyethyl) phosphate Solution in Acetone, 100μg/mL, ris(2-butoxyethyl)phosphate, TBEP/KP-140/Tris(2-butoxyethyl) phosphate/Tributoxy Ethyl Phosphate

Tris(2-butoxyethyl) phosphate is a chemical compound used primarily as a flame retardant and plasticizer.

Tris(2-butoxyethyl) phosphate is a type of organophosphate ester with the chemical formula 

Tris(2-butoxyethyl) phosphate appears as a colorless to yellow, oily liquid that is relatively stable under normal conditions.

Tris(2-butoxyethyl) phosphate is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl. 

Tris(2-butoxyethyl) phosphate has a role as an environmental contaminant and a flame retardant.

Tris(2-butoxyethyl) phosphate  is a slightly yellow viscous liquid.   

Tris(2-butoxyethyl) phosphate is an organic flame retardant. 

Tris(2-butoxyethyl) phosphate shows PXR agonistic activity. 

Tris(2-butoxyethyl) phosphate was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Tris(2-butoxyethyl) phosphate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

Tris(2-butoxyethyl) phosphate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

Tris(2-butoxyethyl) phosphate belongs to the class of organophosphate triesters, widely used as flame retardants and plasticizers in a variety of commercial products such as textiles, foams, polymers, paints, hydraulic fluids, etc.

Tris(2-butoxyethyl) phosphate is an organic flame retardant.

Tris(2-butoxyethyl) phosphate shows PXR agonistic activity. 

Tris(2-butoxyethyl) phosphate was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Tris(2-butoxyethyl) phosphate is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl. 

Tris(2-butoxyethyl) phosphate has a role as an environmental contaminant and a flame retardant.

Phosphate ester flame retardants are human-made chemicals added to consumer and industrial products for the purpose of reducing flammability. 

Phosphate ester flame retardants are composed of a group of chemicals with similar properties but slightly different structures. 

Phosphate esters are typically liquids at room temperature, however, some are solids.

Tris(2-butoxyethyl) phosphate  is a slightly yellow viscous liquid. 

Tris(2-butoxyethyl) phosphate is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming. 

Tris(2-butoxyethyl) phosphate is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers. 

Tris(2-butoxyethyl) phosphate is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers. 

The above properties in combination with inherent flame retardancy makes Tris(2-butoxyethyl) phosphate  a real multifunctional additive essential to many polymer formulations.

Tris(2-butoxyethyl) phosphate may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique.

Primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.

Tris(2-butoxyethyl) phosphate exhibits PXR agnostic activity and is an organic flame retardant.

Tris(2-butoxyethyl) phosphate is a fire-resistant and light-stable plasticizer for food-contact products, resins & elastomers in floor finishes and waxes. 

Tris(2-butoxyethyl) phosphate is a useful research chemical suitable for rubber stoppers in blood specimen containers.

Tris(2-butoxyethyl) phosphate emits toxic fumes of phosphorous oxides when heated to decomposition.

Tris(2-butoxyethyl) phosphate can be used as a resin solvent, plastisol viscosity modifier, and antifoam agent for synthetic rubber, plastics & lacquers.

Tris(2-butoxyethyl) phosphate is a phosphorothioate that is used to inhibit the activity of the enzyme polymerase chain reaction. 

Tris(2-butoxyethyl) phosphate has been shown to induce apoptosis in vitro, which may be due to its ability to decrease mitochondrial membrane potential and interfere with signal pathways. 

Tris(2-butoxyethyl) phosphate has not been shown to affect human serum α1-acid glycoprotein or dimethyl fumarate levels. 

Tris(2-butoxyethyl) phosphate is an efficient inhibitor of DNA polymerase activity and mitochondrial DNA synthesis in vivo, but Tris(2-butoxyethyl) phosphate does not significantly affect mitochondrial membrane potential or cell proliferation. 

Tris(2-butoxyethyl) phosphate is a flame retardant plasticizer, mainly used for flame retardant and plasticization of polyurethane rubber, cellulose, polyvinyl alcohol, etc. 

Tris(2-butoxyethyl) phosphate has good low temperature characteristics.

Tris(2-butoxyethyl) phosphate is used in floor polishes and as a plasticizer in rubber and plastics. 

The worldwide production volume is not available but is estimated to be in the range of 5000–6000 tonnes.

Tris(2-butoxyethyl) phosphate is used in floor polish, water based adhesives, inks, wall coatings and paints in a variety of resin systems. 

Tris(2-butoxyethyl) phosphate is used as a readily biodegradable non-silicone de-airing/antifoam agent in textile application, reducing the viscosity of plastisols and imparts exceptional low temperature flexibility to plastics and acrylonitrile rubbers.

Tris(2-butoxyethyl) phosphate  is a slightly yellow viscous liquid. 

Tris(2-butoxyethyl) phosphate is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl. 

Tris(2-butoxyethyl) phosphate has a role as an environmental contaminant and a flame retardant.

Uses of Tris(2-Butoxyethyl) Phosphate:

Tris(2-butoxyethyl) phosphate is a flame retardant plasticizer, mainly used for flame retardant and plasticizing of polyurethane rubber, cellulose, polyvinyl alcohol, etc., with good low temperature characteristics. 

Plasticizer tbep is used as a flame retardant plasticizer and processing aid for rubber, cellulose and resin. 

Tris(2-butoxyethyl) phosphate is recommended for acrylonitrile rubber, cellulose acetate, epoxy resin, ethyl cellulose, polyvinyl acetate and thermoplastic and thermosetting polyurethane.

Tris(2-butoxyethyl) phosphate is used as a plasticizer for resins and elastomers, in floor finishes and waxes, as a flame retardant, as a plasticizer for rubber stoppers in blood specimen containers, and as a fire-resistant and light-stable plasticizer for products intended for food contact.

Occupational exposure is likely to be by skin absorption during production and from floor polishes.

Tris(2-butoxyethyl) phosphate is used as solvent for resins, a viscosity modifier in plastisols, and an antifoam agent for synthetic rubber, plastics, and lacquers.   

Tris(2-butoxyethyl) phosphate may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique. 

Primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.

Tris(2-butoxyethyl) phosphate is a flame retardant plasticizer, mainly used for flame retardant and plasticizing of polyurethane rubber, cellulose, polyvinyl alcohol, etc., with good low temperature characteristics.

Industry Uses:

Adhesives and sealant chemicals

Flame retardants

Paint additives and coating additives not described by other categories

Plasticizers

Uses at industrial sites:

Tris(2-butoxyethyl) phosphate is used in the following products: polymers, textile treatment products and dyes and washing & cleaning products.

Tris(2-butoxyethyl) phosphate is used for the manufacture of: plastic products and textile, leather or fur.

Release to the environment of Tris(2-butoxyethyl) phosphate can occur from industrial use: in the production of articles, as processing aid and in processing aids at industrial sites.

Consumer Uses:

Tris(2-butoxyethyl) phosphate is used in the following products: washing & cleaning products, polishes and waxes, plant protection products and water treatment chemicals.

Other release to the environment of Tris(2-butoxyethyl) phosphate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Other Consumer Uses:

Adhesives and sealants

Cleaning and furnishing care products

Lubricants and greases

Paints and coatings

Plastic and rubber products not covered elsewhere

Widespread uses by professional workers:

Tris(2-butoxyethyl) phosphate is used in the following products: plant protection products, hydraulic fluids, lubricants and greases, metal working fluids, washing & cleaning products and polishes and waxes. Tris(2-butoxyethyl) phosphate has an industrial use resulting in manufacture of another substance (use of intermediates). Tris(2-butoxyethyl) phosphate is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging. Other release to the environment of Tris(2-butoxyethyl) phosphate is likely to occur from: outdoor use as processing aid and indoor use as processing aid.

Household & Commercial/Institutional Products:

Auto Products

Commercial / Institutional

Home Maintenance

Inside the Home

Applications of Tris(2-Butoxyethyl) Phosphate:

Tris(2-butoxyethyl) phosphate is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.

Tris(2-butoxyethyl) phosphate is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers. 

The above properties in combination with inherent flame retardancy makes Tris(2-butoxyethyl) phosphate a real multifunctional additive essential to many polymer formulations.

Flame retardant:

Tris(2-butoxyethyl) phosphate exhibits PXR agnostic activity and is an organic flame retardant.

Tris(2-butoxyethyl) phosphate is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.

Tris(2-butoxyethyl) phosphate is ussed as a flame retardant in various plastics, particularly in flexible polyurethane foams and PVC.

Plasticizer:

Acts as a plasticizer in polymers to enhance flexibility and durability.

Additive:

Utilized in coatings, adhesives, and sealants for Tris(2-butoxyethyl) phosphate’s flame retardant properties and to improve performance.

General Manufacturing Information of Tris(2-Butoxyethyl) Phosphate:

Industry Processing Sectors:

Paint and coating manufacturing

Plastic material and resin manufacturing

Rubber product manufacturing

Soap, cleaning compound, and toilet preparation manufacturing

Synthetic rubber manufacturing

Utilities

Wholesale and retail trade

Handling and Storage of Tris(2-Butoxyethyl) Phosphate:

Handling:

Avoid contact with skin, eyes, and clothing.

Use in well-ventilated areas and avoid inhaling vapors or dust.

Follow good hygiene practices, such as washing hands thoroughly after handling Tris(2-butoxyethyl) phosphate.

Storage:

Store in a cool, dry, well-ventilated area away from sources of heat or ignition.

Keep containers tightly closed and properly labeled.

Store away from incompatible materials such as strong oxidizers and acids.

Ensure storage facilities comply with local regulations.

Reactivity and Stability of Tris(2-Butoxyethyl) Phosphate:

Reactivity:

Generally stable under normal conditions.

Avoid contact with strong oxidizers, acids, and bases which can cause reactions.

Conditions to Avoid:

High temperatures, open flames, and sources of ignition.

Incompatible Materials:

Strong oxidizers, acids, and bases.

Stability:

Chemical Stability:

Stable under recommended storage conditions.

Decomposition Products:

May release harmful gases or fumes upon decomposition.

Avoid exposure to high temperatures or conditions that could cause decomposition.

Hazardous Reactions:

May undergo hazardous reactions under certain conditions or in the presence of incompatible materials.

First Aid Measures of Tris(2-Butoxyethyl) Phosphate:

Inhalation:

Move the person to fresh air immediately.

If symptoms such as coughing or difficulty breathing persist, seek medical attention.

Skin Contact:

Remove contaminated clothing and wash the affected skin with soap and water.

If irritation develops or persists, seek medical advice.

Eye Contact:

Rinse the eyes immediately with plenty of water for at least 15 minutes, holding the eyelids open.

Remove contact lenses if present and easy to do.

Seek medical attention if irritation or discomfort continues.

Ingestion:

Do not induce vomiting unless directed to do so by medical personnel.

Rinse mouth with water.

Seek medical attention immediately, providing details of Tris(2-butoxyethyl) phosphate ingested.

Firefighting Measures of Tris(2-Butoxyethyl) Phosphate:

Suitable Extinguishing Media:

Use foam, dry chemical powder, or carbon dioxide (CO₂) to extinguish fires.

Water spray can also be used to cool fire-exposed containers and structures.

Specific Hazards:

Combustible liquid; may produce hazardous fumes such as phosphorus oxides when burned.

Vapors may be harmful if inhaled.

Protective Equipment for Firefighters:

Wear self-contained breathing apparatus (SCBA) and full protective clothing.

Ensure adequate ventilation in the area.

Firefighting Procedures:

Move containers from the fire area if Tris(2-butoxyethyl) phosphate is safe to do so.

Use water to cool containers that are exposed to flames.

Avoid breathing smoke and vapors from the fire.

Additional Considerations:

Ensure that firefighting water is not discharged into drains, water sources, or the environment.

Accidental Release Measures of Tris(2-Butoxyethyl) Phosphate:

Personal Precautions:

Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat.

Avoid inhalation of vapors or dust, and avoid contact with skin and eyes.

Ensure adequate ventilation in the area.

Environmental Precautions:

Prevent the material from entering drains, water sources, or soil.

Contain the spill to minimize environmental impact.

Methods for Containment and Cleanup:

Absorb the spill with inert materials like sand or vermiculite.

Collect and place the absorbed material into a suitable, labeled waste container.

Clean the contaminated area with soap and water, ensuring that the area is thoroughly dry before resuming work.

Dispose of waste materials in accordance with local regulations.

Decontamination:

Wash contaminated surfaces and equipment with water and soap or a suitable cleaning agent.

Dispose of contaminated cleaning materials properly.

Exposure Controls/Personal Protection of Tris(2-Butoxyethyl) Phosphate:

Occupational Exposure Limits:

Adhere to local or national regulations for permissible exposure limits.

Use monitoring methods to ensure that exposure levels remain below these limits.

Engineering Controls:

Ensure adequate ventilation, such as local exhaust systems or general ventilation, to minimize inhalation exposure.

Use enclosures, containment devices, or other engineering controls as necessary.

Personal Protective Equipment (PPE):

Respiratory Protection: Use an appropriate respirator if ventilation is insufficient or if exposure limits are exceeded.

Hand Protection:

Wear protective gloves made from materials resistant to the chemical.

Eye Protection:

Use safety goggles or face shields to protect eyes from splashes or vapors.

Skin Protection:

Wear protective clothing and footwear to prevent skin contact.

Identifiers of Tris(2-Butoxyethyl) Phosphate:

CAS: 78-51-3

European Community (EC) Number: 201-122-9

IUPAC Name: tris(2-butoxyethyl) phosphate

Molecular Formula: C18H39O7P

Molecular Weight: 398.5 g/mol

Properties of Tris(2-Butoxyethyl) Phosphate:

Melting point: -70°C

Boiling point: 215-228 °C4 mm Hg(lit.)

Density: 1.006 g/mL at 25 °C(lit.)

vapor density: 13.7 (vs air)

vapor pressure: 0.03 mm Hg ( 150 °C)

refractive index: n20/D 1.438(lit.)

Flash point: >230 °F

storage temp.: Store at -20°C

solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form: Liquid

color: Clear colorless to very slightly yellow

Viscosity: 12.2cp (20C)

Water Solubility: Soluble

Stability: Stable. 

Combustible. 

Incompatible with strong oxidizing agents.

Molecular Weight: 398.5

XLogP3: 2.8

Hydrogen Bond Acceptor Count: 7

Rotatable Bond Count: 21

Exact Mass: 398.24334058

Monoisotopic Mass: 398.24334058

Topological Polar Surface Area: 72.4

Heavy Atom Count: 26

Complexity: 281

Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes

Appearance: Colorless to pale yellow liquid.

Chemical Formula: C12H27O4P.

Molecular Weight: Approximately 246.3 g/mol.

Density: Around 1.05 g/cm³.

Boiling Point: 220°C (428°F).

Flash Point: 121°C (250°F).

Solubility: Insoluble in water; soluble in most organic solvents.

Names of Tris(2-Butoxyethyl) Phosphate:

IUPAC Names:

Ethanol, 2-butoxy-, phosphate (3:1)

TBEP

Tributoxyethyl Phosphate

Tris(2-butoxyethyl) Phosphate

Tris(2-butoxyethyl) phosphate

tris(2-butoxyethyl) phosphate

Tris(2-butoxyethyl)phosphate

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