DIETHANOLAMINE (DETANOLAMN)

DIETHANOLAMINE (DETANOLAMN)

DIETHANOLAMINE (DETANOLAMN)

CAS Number: 111-42-2, 61791-44-4, 61791-46-6
EC Number: 203-868-0, 263-177-5, 263-179-6

SYNONMYS:

diethanolamine; diethanolamine acetate; diethanolamine bisulfate; diethanolamine fumarate; diethanolamine hydrochloride; diethanolamine maleate; diethanolamine maleate (1:1); diethanolamine phosphate; diethanolamine sulfate (1:1); diethanolamine sulfate (2:1); diethanolamine sulfite; diethanolamine sulfite (1:1); diethanolammonium sulfate; DIETHANOLAMINE; 2,2′-Iminodiethanol; 111-42-2Diolamine; Iminodiethanol; Bis(2-hydroxyethyl)amine; Diethylolamine N,N-Diethanolamine; Diethanolamin; 2,2′-Dihydroxydiethylamine; Ethanol, 2,2′-iminobis-; 2,2′-Iminobisethanol; Di(2-hydroxyethyl)amine; 2,2′- Azanediyldiethanol; Diaethanolamin; Bis(hydroxyethyl)amine; 2-(2-Hydroxyethylamino)ethanol; Niax DEOA-LF; N,N’-Iminodiethanol; N,N-Bis(2-hydroxyethyl)amine; 2,2′-Iminodi-1-ethanol; 2-[(2-hydroxyethyl)amino]ethan-1-ol; Dabco DEOA-LF; N,N-Di(hydroxyethyl)amine; NCI-C55174; H2dea; Diolamine (VAN); Di(beta- hydroxyethyl)amine; 2,2-Iminodiethanol; 2,2’Iminobisethanol; Diethanolamin [Czech]; Bis-2-hydroxyethylamine; Diaethanolamin [German]; Dihydroxyethyl tallowamine oxide; Diethylamine, 2,2′-dihydroxy-; UNII-AZE05TDV2V; 2,2′-Iminobis[ethanol]; 2-[(2-Hydroxyethyl)amino]ethanol; Ethanol, 2,2′-iminodi- NSC 4959; CCRIS 5906; Diethanolamine (NF); Diethanolamine [NF]; HSDB 924; EINECS 203-868-0; AZE05TDV2V; Bis(2-hydroxyethyl)tallow amine oxide; BRN 0605315 bis-(2-hydroxy-ethyl)-amine; AI3-15335; Amines, tallow alkyl dihydroxyethyl, oxides; CHEBI:28123; ZBCBWPMODOFKDW-UHFFFAOYSA-N; 61791-44-4; bis[2-Hydroxyethyl]amine; DSSTox_CID_1932; 2,2′-Iminobisethanol, N-tallow alkyl, N-oxide; DSSTox_RID_76411; DSSTox_GSID_21932; 61791-46-6; Ethanol, 2,2′-iminobis-,N-tallow alkyl, N-oxide; AMINE,DIETHYL,2,2′-DIHYDROXY DIETHANOLAMINE; Ethanol, 2,2′-iminobis-, N-tallow alkyl derivs, N-oxides; Diolamine [INN]CAS-111-42-2; Diethanolamine [USAN:NF]; diethanolarnine; diethanol amine; Aliphatic amine; EINECS 263-177-5; EINECS 263-179-6; 2,2′-Iminobis; Diethanolamine,99%; Ethanol,2′-iminodi-; N, N-diethanol amine; Ethanol,2′-iminobis-; 2, 2′-Iminodiethanol; AC1L1QAN; bis-(2-hydroxyethyl)amine; DIETHANOLAMINE, ACS; bis(2-Hydroxy Ethyl)amine; bmse000371; Diethanol, 2,2′-imino-; EC 203-868-0; Diethylamine,2′-dihydroxy-; SCHEMBL2324; bis-(2-hydroxyethyl)-amine; NCIOpen2_008991WLN: Q2M2Q; (HOCH2 CH2)2NH; ghl.PD_Mitscher_leg0.542; 4-04-00-01514 (Beilstein Handbook Reference); bis-(2-hydroxy-ethyl) amine; Ethanol, 2,2′-iminobis-, N-tallow alkyl derivs.; KSC174Q6T; MLS001065608; BIDD:GT0277; ACMC-20999j; Bis(2-Hydroxyethyl)Tallowamine; Diethanolamine, LR, >=98%; AC1Q7D76; CHEMBL119604;Diethanolamine, 99% 500g; SCHEMBL5200828; DTXSID3021932; 2-(2-hydroxy-ethylamino)ethanol; 2-(2-hydroxyethylamino)-ethanol; CTK0H4869; NSC4959; 2,2′-Azanediylbis(ethan-1-ol); 50909-06-3 (maleate); 66085-61-8 (sulfite); Diethanolamine, ACS reagent grade; MolPort-001-790-590; 14426-21-2 (hydrochloride); 2-(2-hydroxy-ethylamino)-ethanol; Diethanolamine, analytical standard; Diethanolamine, puriss., 99.0%; Ethanol, 2,2′-iminobis-, N-tallow alkyl derivs., N-oxides; HMS2269D18; 23251-72-1 (acetate salt); KS-00000X8O; NSC-4959; STR03965; ZINC5975487; 29870-32-4 (phosphate salt); Tox21_201701; Tox21_300034; ANW-16277; Diethanolamine, BioXtra, >=98.5%; LS-532i; MFCD00002843; SBB059779; STL264122; AKOS000119884; MCULE-9803420258; RP18852; RTR-002261; TRA0002778;TRANSGENIC LECM (DIETHANOLAMINE); Diethanolamine, ACS reagent, >=98.5%; NCGC00091478-01; NCGC00091478-02; NCGC00091478-03; NCGC00091478-04; NCGC00254061-01;NCGC00259250-01; 59219-56-6 (sulfate[1:1]); 66085-61-8 (sulfite[1:1]); AJ-26664; AN-43069; Diethanolamine, reagent grade, >=98.0%; KB-49774; SC-43898;SMR000112130; 20261-60-3 (sulfate[2:1] salt); LS-190896; TR-002261; Diethanolamine, BioUltra, >=99.5% (GC); Diethanolamine, SAJ first grade, >=98.0%; FT-0624757; I0008; S0376; ST51046050; Diethanolamine, JIS special grade, >=99.0%; 3224-EP2269610A2; 3224-EP2269977A2; 3224-EP2269989A1; 3224-EP2269990A1; 3224-EP2270002A1; 3224-EP2270010A1; 3224-EP2270505A1; 3224-EP2272517A1; 3224-EP2272817A1; 3224-EP2272822A1; 3224-EP2272832A1; 3224-EP2272841A1; 3224-EP2272849A1;3224-EP2275105A1; 3224-EP2275401A1; 3224-EP2275411A2; 3224-EP2275412A1; 3224-EP2277848A1; 3224-EP2279750A1; 3224-EP2280001A1; 3224-EP2280006A1; 3224-EP2281563A1; 3224-EP2281813A1; 3224-EP2281815A1; 3224-EP2281816A1; 3224-EP2281818A1; 3224-EP2281821A1; 3224-EP2281823A2; 3224-EP2284159A1; 3224-EP2286811A1;3224-EP2287152A2; 3224-EP22871551; 3224-EP2289510A1; 3224-EP2289868A1; 3224-EP2289890A1; 3224-EP2289893A1; 3224-EP2289896A1; 3224-EP2292592A1; 3224-EP2292593A2; 3224-EP2292613A1; 3224-EP2295055A2; 3224-EP2295402A2; 3224-EP2295406A1; 3224-EP2295407A1; 3224-EP2295427A1; 3224-EP2295437A1; 3224-EP2295438A1;3224-EP2298731A1; 3224-EP2298734A2; 3224-EP2298736A1; 3224-EP2298742A1; 3224-EP2298743A1; 3224-EP2298744A2; 3224-EP2298746A1; 3224-EP2298761A1;3224-EP2298770A1; 3224-EP2298772A1; 3224-EP2298775A1; 3224-EP2298778A1; 3224-EP2301933A1; 3224-EP2301936A1; 3224-EP2305219A1; 3224-EP2305250A1; 3224-EP2305640A2; 3224-EP2305642A2; 3224-EP2305646A1; 3224-EP2305679A1; 3224-EP2308510A1; 3224-EP2308562A2; 3224-EP2308812A2;; 3224-EP2308828A2; 3224-EP2308838A1;3224-EP2308839A1; 3224-EP2308841A2; 3224-EP2308848A1; 3224-EP2308873A1; 3224-EP2308875A1; 3224-EP2311453A1; 3224-EP2311815A1; 3224-EP2311827A1; 3224-EP2311831A1; 3224-EP2311842A2; 3224-EP2314295A1; 3224-EP2314298A1; 3224-EP2314574A1; 3224-EP2314584A1; 3224-EP2316457A1; 3224-EP2316458A1; 3224-EP2316459A1;3224-EP2316470A2; 3224-EP2316825A1; 3224-EP2316826A1; 3224-EP2316827A1; 3224-EP2316828A1; 3224-EP2316831A1; 3224-EP2316832A1; 3224-EP2316833A1; 3224-EP2316836A1; 3224-EP2371809A1; 3224-EP2371811A2; 3224-EP2372017A1; 3224-EP2374788A1; 5269-EP2284172A1; C06772; D02337; 40851-EP2275421A1; 40851-EP2292630A1;40851-EP2311830A1; 56752-EP2284166A1; 56752-EP2298769A1; 56752-EP2298773A1; 56752-EP2308878A2; I14-2695; J-506841; F2190-0311; Z966690660; BFC20619-2EDF-4764-8E91-830AA892BD39; Diethanolamine, puriss. p.a., ACS reagent, >=99.0% (GC); InChI=1/C4H11NO2/c6-3-1-5-2-4-7/h5-7H,1-4H; Diethanolamine, United StatesPharmacopeia (USP) Reference Standard; Trolamine impurity B, European Pharmacopoeia (EP) Reference Standard; Diethanolamine, Pharmaceutical SecondaryStandard; Certified Reference Material; 8033-73-6; dietanolmin; diyetenalomin; diyetenalamin; dietenalomin; dietenelomin; dietnolmin; dietanlamin

 

Properties of diethanolamine

Molecular Formula:C4H11NO2
Molecular Weight:105.137 g/mol
Flash Point:176°(349°F)
Boiling Point:268-270° 
Flash Point:176°(349°F) 
Density:1.097

  Diethanolamine (DEA or DEOA) is a colorless, viscous liquid organic chemical compound that is both a secondary amine and a dialcohol. According to the International Agency for Research, the compound is a suspected carcinogen to humans. The hydrophilic liquid is used as a surfactant as well as a corrosion inhibitor. DEA is also used to remove hydrogen sulfide from natural gas.

 

 

Reactivity Profile

  Diethanolamine is an aminoalcohol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. This compound is hygroscopic. It may be sensitive to exposure to air and light. This compound can react with oxidizing materials, acids, CO2, copper alloys, aluminum, zinc, galvanized iron and copper.

 

 

Applications

  Diethanolamine is used in the preparation of morpholine and diethanolamides, which is an active ingredient in cosmetics and shampoos. It acts as a surfactant and a corrosion inhibitor. It is utilized to remove hydrogen sulfide and carbon dioxide from natural gas. Further, it is an intermediate used in the rubber chemicals, as a humectant and a softening agent, and as an emulsifier and dispersing agent in agricultural chemicals. In addition to this, it is used in cutting oils, cleaners, soaps, polishers, and pharmaceuticals.

 

 

Health Hazard Information

 

Acute Effects:

  Acute inhalation exposure to diethanolamine in humans may result in irritation of the nose and throat, and dermal exposure may result in irritation of the skin.

  Animal studies indicate that exposure to diethanolamine by intravenous injections can cause increased blood pressure, pupillary dilatation, and salivation. At very high doses in animals, sedation, and coma may result. 

  Acute animal studies have shown that dermal exposure to diethanolamine may burn skin, and eye contact with the chemical may impair vision.

  Acute animal tests in rats have shown diethanolamine to have moderate acute toxicity from oral exposure.

 

 

Chronic Effects (Noncancer): 

  No information is available on the chronic effects of diethanolamine in humans.

  Animal studies have reported effects on the liver, kidney, blood, and CNS from chronic oral exposure to diethanolamine.

  Skin lesions were observed in mice following daily topical administration of diethanolamine.

  EPA has not established a Reference Concentration (RfC) or a Reference Dose (RfD) for diethanolamine. The California Environmental Protection Agency (CalEPA) has established a chronic reference exposure level of 0.02 milligrams per cubic meter (mg/m ) for diethanolamine based on effects on the blood in rats. The CalEPA reference exposure level is a concentration at or below which adverse health effects are not likely to occur. It is not a direct estimator of risk but rather a reference point to gauge the potential effects. At lifetime exposures increasingly greater than the reference exposure level, the potential for adverse health effects increases.

Reproductive/Developmental Effects:

  No information is available on the reproductive or developmental effects of diethanolamine in humans.

  Animal studies have reported testicular degeneration and reduced sperm motility and count from oral exposure to diethanolamine.

Cancer Risk:

  No information is available on the carcinogenic effects of diethanolamine in humans.

  EPA has not classified diethanolamine for carcinogenicity.

 

Air & Water Reactions

Water soluble.

Fire Hazard

Special Hazards of Combustion Products: Irritating vapors are generated when heated.

Health Hazard

Irritation of eyes and skin. Breathing vapors may cause coughing, a smothering sensation, nausea, headache.

 

Diethanolamin özellikleri

Moleküler Formül: C4H11NO2
Moleküler Arlk: 105.137 g / mol
Parlama Noktas: 176 ° (349 ° F)
Kaynama Noktas: 268-270 °
Parlama Noktas: 176 ° (349 ° F)
Younluk: 1,097

  Dietanolamin (DEA veya DEOA), hem ikincil bir amin hem de bir dialkol olan renksiz, viskoz bir sv organik kimyasal bileiktir. Uluslararas Aratrma Ajans’na göre, bileik insanlara karsinojen olduundan üpheleniliyor. Hidrofilik sv, bir sürfaktan ve bir korozyon inhibitörü olarak kullanlr. DEA ayrca hidrojen sülfitin doal gaz uzaklatrmak için kullanlr.

 

Reaktivite Profili

  Dietanolamin bir aminoalkoldür. Aminler kimyasal bazlardr. Tuzlar art su oluturmak için asitleri nötralize ederler. Bu asit-baz reaksiyonlar ekzotermiktir. Nötralizasyondaki aminin molü bana gelien s miktar büyük ölçüde aminin baz olarak mukavemetinden bamszdr. Aminler, izosiyanatlar, halojenlenmi organikler, peroksitler, fenoller (asidik), epoksitler, anhidritler ve asit halidler ile uyumsuz olabilir. Yanc gaz halindeki hidrojen, hidratlar gibi güçlü indirgeyici maddelerle kombinasyon halinde aminler tarafndan üretilir. Bu bileik higroskopiktir. Havaya ve a maruz kalmak hassas olabilir. Bu bileik, oksitleyici maddeler, asitler, CO2, bakr alamlar, alüminyum, çinko, galvanizli demir ve bakr ile reaksiyona girebilir.

 

Uygulamalar

  Dietanolamin, kozmetikte ve ampuanlarda aktif bir madde olan morfolin ve dietanolamidlerin hazrlanmasnda kullanlr. Bir sürfaktan ve bir korozyon inhibitörü olarak görev yapar. Hidrojen sülfür ve karbon dioksitin doalgazdan uzaklatrlmas için kullanlr. Ayrca, kauçuk kimyasallarnda, bir nemlendirici ve yumuatc madde olarak ve tarm kimyasallarnda bir emülsifiye edici ve datc madde olarak kullanlan bir ara maddedir. Buna ek olarak, yalar, temizleyicileri, sabunlar, cilalayclar ve ilaçlar kesmek için kullanlr.

 

Salk Tehlikesi Bilgileri

 

Akut Etkiler:

  nsanlarda diyetuanolamine akut inhalasyon maruziyeti, burun ve boazda tahrie neden olabilir ve deriye maruz kalmak deride tahrie neden olabilir.

  Hayvan çalmalar, intravenöz enjeksiyonlarla diyettanolamine maruz kalmann artm kan basncna, pupilla dilatasyonuna ve salivasyona neden olabileceini göstermektedir.

  Hayvanlarda çok yüksek dozlarda sedasyon ve koma ortaya çkabilir.

  Akut hayvan çalmalar, dietanolamine kar dermal maruziyetin cildi yakabileceini ve kimyasal madde ile göz temasnn görmeyi bozabileceini göstermitir.

  Sçanlarda akut hayvan testleri, oral maruz kalmadan orta derecede akut toksisiteye sahip diyettanolamini göstermitir.

 

Kronik Etkiler (Noncancer):

  Dietanolaminin insanlarda kronik etkileri hakknda bilgi bulunmamaktadr.

  Hayvan çalmalar, karacier, böbrek, kan ve CNS’nin diyetetanolamine kronik oral maruziyetinden etkilerini bildirmitir.

  Dietanolaminin günlük topikal uygulamasn takiben farelerde deri lezyonlar gözlenmitir.

  EPA, dietanolamin için bir Referans Konsantrasyon (RfC) veya bir Referans Doz (RfD) oluturmamtr. Kaliforniya Çevre Koruma Ajans (CalEPA), sçanlarda kan üzerindeki etkilere dayal olarak dietanolamin için metreküp bana 0.02 miligram (mg / m) bir kronik referans maruziyet seviyesi oluturmutur. TheCalEPA referans maruziyet seviyesi, olumsuz salk etkilerinin meydana gelmesinin olas olmad bir veya daha düük konsantrasyondur. Bu, dorudan bir risk tahmincisi deil, potansiyel etkileri ölçmek için bir referans noktasdr. Yaam süresi maruziyetinde, referans maruziyet seviyesinden giderek daha fazla maruz kalma durumunda, olumsuz salk etkilerinin potansiyeli artmaktadr.

Üreme / Geliimsel Etkiler:

  nsanlarda dietanolaminin üreme veya geliimsel etkileri hakknda bilgi bulunmamaktadr.

  Hayvan çalmalar, testiküler dejenerasyonu ve sperm motilitesini azalttn ve oral yoldan dietanolamine maruz kaldn bildirmitir.

Kanser Riski:

  nsanlarda dietanolaminin kanserojen etkileri hakknda bilgi bulunmamaktadr.

  EPA, diyetinolamini kanserojenlik açsndan snflandrmamtr.

 

 

Hava ve Su Reaksiyonlar

Suda çözünür.

 

Yangn tehlikesi

Yanma Ürünlerinin Özel Tehlikeleri: Istldnda tahri edici buharlar oluur.

 

Salk tehlikesi

Gözlerin ve cildin tahri olmas. Solunum buharlar öksürüe, boulma hissine, mide bulantsna, ba arsna neden olabilir.