DERIPHAT 160c
Deriphat 160 c
(Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt) (Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu)
CAS No. : 14960-06-6
EC No. : 239-032-7
Synonyms:
SODIUM LAURIMINODIPROPIONATE; 14960-06-6; Deriphat 160 c; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; Deriphat 160 c; EC 239-032-7; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395; Deriphat 160 c; Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; Deriphat 160 c; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Deriphat 160 c; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Deriphat 160 c; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; Deriphat 160 c; SODIUM LAURIMINODIPROPIONATE; Deriphat160C; DERIPHAT 160C; Deriphat 160C; DERIPHAT 160 C; Derphat 160 C; Deriphot 160 C; Deriphat 160; Derphat 160; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt;3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; Deriphat 160 c; N-Lauryl-β-iminodipropionic acid, sodium salt; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; Deriphat 160 c; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; Deriphat 160 c; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; Deriphat 160 c; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; 14960-06-6; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; EC 239-032-7; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395;Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Deriphat 160 c; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; 3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; N-Lauryl-β-iminodipropionic acid, sodium salt; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; 14960-06-6; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; EC 239-032-7; Deriphat 160 c; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395;Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Q27268223; Deriphat160C; DERIPHAT 160C; Deriphat 160C; DERIPHAT 160 C; Derphat 160 C; Deriphot 160 C; Deriphat 160; Derphat 160; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt;3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; N-Lauryl-β-iminodipropionic acid, sodium salt; Deriphat 160 c; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; Deriphat 160 c; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; 14960-06-6; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; EC 239-032-7; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395;Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt;3655-00-3 [RN]; Deriphat160C; DERIPHAT 160C; Deriphat 160C; DERIPHAT 160 C; Derphat 160 C; Deriphot 160 C; Deriphat 160; Derphat 160; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; N-Lauryl-β-iminodipropionic acid, sodium salt; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; 14960-06-6; Deriphat 160 c; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; Deriphat160C; DERIPHAT 160C; Deriphat 160C; DERIPHAT 160 C; Derphat 160 C; Deriphot 160 C; Deriphat 160; Derphat 160; EINECS 239-032-7; Deriphat 160 c; EC 239-032-7; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395; Deriphat 160 c; Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; Deriphat 160 c; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Deriphat 160 c; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Deriphat 160 c; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; Deriphat 160 c; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt;3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; Deriphat 160 c; N-Lauryl-β-iminodipropionic acid, sodium salt; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; Deriphat 160 c; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; Deriphat 160 c; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; Deriphat 160 c; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; 14960-06-6; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; EC 239-032-7; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395;Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Deriphat160C; DERIPHAT 160C; Deriphat 160C; DERIPHAT 160 C; Derphat 160 C; Deriphot 160 C; Deriphat 160; Derphat 160; Sodium Lauriminodipropionic Acid; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Deriphat 160 c; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; 3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; N-Lauryl-β-iminodipropionic acid, sodium salt; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; 14960-06-6; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; EC 239-032-7; Deriphat 160 c; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395;Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt;3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; N-Lauryl-β-iminodipropionic acid, sodium salt; Deriphat 160 c; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; Deriphat 160 c; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c; SODIUM LAURIMINODIPROPIONATE; Deriphat160C; DERIPHAT 160C; Deriphat 160C; DERIPHAT 160 C; Derphat 160 C; Deriphot 160 C; Deriphat 160; Derphat 160; 14960-06-6; UNII-7G447D0DH9; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; 7G447D0DH9; Sodium N-lauryl-beta-iminodipropionate; EINECS 239-032-7; EC 239-032-7; N-Lauryl-beta-iminodipropionic acid, sodium salt; SCHEMBL432395;Sodium N-(2-carboxyethyl)-N-dodecyl-beta-alaninate; Sodium Lauriminodipropionic Acid; CHEMBL1651997; DTXSID7041207; odium N-(2-carboxyethyl)-N-dodecyl-?-alaninate; Sodium N-(2-carboxyethyl)-N-dodecyl-ss-alaninate; N-(2-Sodiooxycarbonylethyl)-N-dodecyl-beta-alanine; Q27268223; N-(2-Carboxyethyl)-N-dodecyl-beta-alanine, monosodium salt; beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, sodium salt (1:1); 3-[(2-Carboxyéthyl)(dodécyl)amino]propanoate de sodium [French] [ACD/IUPAC Name]; Natrium-3-[(2-carboxyethyl)(dodecyl)amino]propanoat [German] [ACD/IUPAC Name]; Sodium 3-[(2-carboxyethyl)(dodecyl)amino]propanoate [ACD/IUPAC Name]; SODIUM LAURIMINODIPROPIONATE; ?-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt;3655-00-3 [RN]; EINECS 239-032-7; N-(2-Carboxyethyl)-N-dodecyl-β-alanine, monosodium salt; N-Lauryl-β-iminodipropionic acid, sodium salt; sodium 3-(2-carboxyethyl-dodecylamino)propanoate; sodium 3-(2-carboxyethyl-dodecyl-amino)propanoate; sodium 3-(2-carboxyethyl-lauryl-amino)propionate; sodium N-(2-carboxyethyl)-N-dodecyl-β-alaninate; β-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Deriphat 160 c; Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, monosodium salt; Beta-Alanin, N- (2-karboksietil) -N-dodesil-, monosodyum tuzu; DERIPHAT; DERIPHOT; DERPHOT; DERPHAT; derphat; derphot; DERPHOT; derphat; Deriphat 160c; Deriphot 160c;
EN
Deriphat 160 c IUPAC Name sodium;3-[2-carboxyethyl(dodecyl)amino]propanoate
Deriphat 160 c InChI InChI=1S/C18H35NO4.Na/c1-2-3-4-5-6-7-8-9-10-11-14-19(15-12-17(20)21)16-13-18(22)23;/h2-16H2,1H3,(H,20,21)(H,22,23);/q;+1/p-1
Deriphat 160 c InChI Key LLKGTXLYJMUQJX-UHFFFAOYSA-M
Deriphat 160 c Canonical SMILES CCCCCCCCCCCCN(CCC(=O)O)CCC(=O)[O-].[Na+]
Deriphat 160 c Molecular Formula C18H34NNaO4
Deriphat 160 c CAS 14960-06-6
Deriphat 160 c Deprecated CAS 195603-51-1
Deriphat 160 c European Community (EC) Number 239-032-7
Deriphat 160 c UNII 7G447D0DH9
Deriphat 160 c DSSTox Substance ID DTXSID7041207
Deriphat 160 c Physical Description Liquid
Deriphat 160 c Consumer Uses Cleaning and furnishing care products
Deriphat 160 c Hazard Classes and Categories Skin Irrit. 2 (71.14%) Eye Dam. 1 (59.4%) Eye Irrit. 2 (40.6%)
Deriphat 160 c Molecular Weight 351.5 g/mol
Deriphat 160 c Hydrogen Bond Donor Count 1
Deriphat 160 c Hydrogen Bond Acceptor Count 5
Deriphat 160 c Rotatable Bond Count 17
Deriphat 160 c Exact Mass 351.238553 g/mol
Deriphat 160 c Monoisotopic Mass 351.238553 g/mol
Deriphat 160 c Topological Polar Surface Area 80.7 Ų
Deriphat 160 c Heavy Atom Count 24
Deriphat 160 c Formal Charge 0
Deriphat 160 c Complexity 313
Deriphat 160 c Isotope Atom Count 0
Deriphat 160 c Defined Atom Stereocenter Count 0
Deriphat 160 c Undefined Atom Stereocenter Count 0
Deriphat 160 c Defined Bond Stereocenter Count 0
Deriphat 160 c Undefined Bond Stereocenter Count 0
Deriphat 160 c Covalently-Bonded Unit Count 2
Deriphat 160 c Compound Is Canonicalized Yes
Deriphat 160 C is an amphoteric surfactant based on sodium N-lauryl-betaiminodipropionate.Deriphat 160 C is a clear yellowish liquid at room temperature and is prone to sedimentation at low temperatures. Deriphat 160 C should be stored indoors in a dry piace.The storage temperature should not be allowed to fall substantially below 20 °C.The congealing point of Deriphat 160 C also need to be taken into account Liquid that has solidified or that shows signs of sedimentation should be heated to 50- 70 °C and homogenized before it is processed. Please mix sufficiently prior to use.Solubility of Deriphat 160 C (10% at 23 °C) In various aqueous solutions of Deriphat 160 C, no impact on viscosity is noticeable. Deriphat 160 C is an amphoteric surfactant for cleaners. It exhibits very good foaming power in hard and soft water.Description Deriphat 160 C is a unique, multi-functional amphoteric surfactant. It can function as a foamer, cleaning agent, corrosion inhibitor, and a hydrotrope. The isoelectric point is 2.4 to 4.2.Benefits:Easy to formulate ultra concentrates Stable in strong acid and alkaline solutions Lasting corrosion inhibition Foam not effected by pH or electrolytes Effective hydrotrope Good emulsifier at low concentrations Listed on CleanGredients approved DfE Solubilizer for cationic germicides Deriphat 160 C is especially valuable for its ability to produce and maintain stable emulsions at extremes of pH. It will function effectively at highly alkaline pH where most cationic, non-ionic and anionic emulsifiers are ineffective.Product: sodium lauriminodipropionate 30% (DERIPHAT 160 C, BASF) CAS No.: 14960-06-6 Deriphat 160 C DERIPHAT 160 C is an amphoteric surfactant for cleaners which is sold as 30% liquid. The product exhibits very good foaming power in hard and soft water. Its stability over a broad pH range allows its use in acidic and alkaline formulations. DERIPHAT® 160 C can be combined with cationic surfactants which are often used as bactericides for disinfectants. DERIPHAT® 160 C is a strong hydrotrope with excellent water solubility over a broad pH range even when high electrolyte concentration is present. DERIPHAT® 160 C is compatible with other common nonionic, anionic and cationic surfactants.Value Excellent hydrotrope, providing good cleaning, wetting and corrosion inhibition.It exhibits very good foaming power in hard and soft water. 3655-00-3 (26256-79-1, 3655-00-3) Deriphat · Deriphat 160c · Deriphat 160 Cadmium is a toxic and hazardous trace metal that has become a serious environmental pollutant since industrialization and intensive farming began in late 19th century. Although there are many established wet-chemical and instrumental methods for qualitative and quantitative determination of cadmium, most involve the formation of the Cd-dithizone complex in the presence of the highly toxic potassium cyanide which is then extracted into carcinogenic chlorinated organic solvents such as chloroform or carbon tetrachloride. The main purpose of this study was to see if a sensitive, simple, quick spectro-chemical method that utilizes safer and less toxic chemicals for cadmium analysis using dithizone could be developed. The results found so far are promising and indicate that in the presence of a chelating surfactant such as Deriphat-160C, the cadmium-dithizone complex in alkaline aqueous medium remains soluble and obeys Beers law in the micro molar Cd concentration range studied. The solutions prepared for spectroscopic measurement did not require KCN nor was it necessary to extract the complex in to chlorinated organic solvents. compound in Deriphat 160C) Deriphat 160 C. 0.38% 0.38% 0.38% 24.3% In this example, Deriphat 160C® could not be dissolved in 29.6% K-glyphosate (aq.) if the concentration of Deriphat 160C was >0.38% (#1 in the table). With the addition of 0.37% C6-9 dimethylamidopropylamine, the hazy formulation became a clear solution (#2). #3 showed that pH effect is not the main reason for the dissolution of the insoluble species in K-glyphosate formulation. This concentration of surfactant in #1 was much too low to offer any benefit to glyphosate efficacy. In order for a surfactant to offer consistent benefit to glyphosate efficacy, the surfactant concentration typically has to be about greater than 7%. However, more than 24.3% Deriphat could be dissolved in the 29.6% K-glyphosate (aq.) if 2% C6-C9 dimethyamidopropylamine was added as the compatibility agent (#4).SODIUM LAURIMINODIPROPIONATE SODIUM LAURIMINODIPROPIONATE is classified as :Antistatic Cleansing Foaming Foam boosting Hair conditioning Surfactant Cosmetics Ingredients containing SODIUM LAURIMINODIPROPIONATE Sodium Lauriminodipropionate and Sodium Lauraminopropionate are sodium salts of substituted propionic acid. Sodium Lauriminodipropionate may be used in the formulation of hair conditioners, hair dyes, bath products and other cleansing products.Sodium Lauriminodipropionate functions as an anti-static agent that prevents or inhibits the build-up of static electricity.sodium lauriminodipropionate beta-alanine, N-(2-carboxyethyl)-n-dodecyl-, sodium salt (1:1)GENERIC NAME:Sodium Lauriminodipropionate 30% Lauriminodipropionic Acid, Sodium Lauriminodipropionate,and Disodium Lauriminodipropionate as Used in Cosmetics Lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate function as hair conditioning agents and surfactant-cleansing agents in cosmetic formulations. The CIR Expert Panel reviewed relevant animal and human data related to the safety of these ingredients in cosmetics. The Panel concluded that lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate are safe as cosmetic ingredients in the present practices of use and concentration.Sodium lauriminodipropionate is the sodium salt of a substituted propionic acid that is used as a surfactant,a hair conditioning agent and an antistatic agent in cosmetic formulations. In a safety assessment for sodium lauriminodipropionate and sodium lauraminopropionate published by the Cosmetic Ingredient Review (CIR) in 1997,the CIR Expert Panel concluded that the available data were insufficient to support safety of both ingredients for use in cosmetics.Additional unpublished data now are available that support the safety of sodium lauriminodipropionate as used in cosmetics. Because of chemical similarities to sodium lauriminodipropionate, the CIR Expert Panel also considered that the newly available data may be extrapolated to the parent compound, lauriminodipropionic acid,and to the disodium salt.Because no new data were available on sodium lauraminopropionate, the CIR Expert Panel did not reopen the final report to include this ingredient and reaffirmed the conclusion of insufficient data for sodium lauraminopropionate.The main impurity in the manufacture of sodium lauriminodipropionate is sodium acrylate.Trace amounts of dodecyl-chain compounds associated with the starting material, dodecylamine, may also be present. Total impurities are typically found at levels less than 2% in the product as sold. Dodecylamine, polyacrylic acid, or sodium polyacrylate have not been detected in batch samples of the commercial product. In the production of sodium lauriminodipropionate, trace levels of sodium lauraminopropionate may occur.Lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate are used as hair conditioning agents and surfactant-cleansing agents in cosmetic formulations.The monosodium and disodium salts are also used as antistatic agents and the monosodium salt is used as a surfactant-foam booster.Table 3 presents the historical and current product formulation data for sodium lauriminodipropionate.According to information supplied to the Food and Drug Administration (FDA) by industry as part of the Voluntary Cosmetic Registration Program (VCRP), sodium lauriminodipropionate was used in a total of 23 cosmetic formulations at the time of the first safety assessment.An industry survey reported use concentration range of 1-10%.1 Currently, VCRP data indicate that sodium lauriminodipropionate is used in 10 cosmetic formulations, half of which are in hair conditioners.In a survey of current use concentrations conducted by the Personal Care Products Council, sodium lauriminodipropionate is used at a concentration of 0.05% in hair conditioners.Currently, the VCRP data indicate that disodium lauriminodipropionate is used in 2 cosmetic formulations,both of which are face and neck preparations.No uses are reported for lauriminodipropionic acid.No use concentrations were reported for the acid or the disodium salt in a survey of current use concentration conducted by the.Sodium lauriminodipropionate has applications in heavy-duty alkaline cleaners, corrosion inhibitors, leather cleaners,and acid cleaners.From the Final Report on the Safety Assessment of Sodium Lauriminodipropionate.SODIUM LAURIMINODIPROPIONATE While specific information on the absorption, distribution, metabolism, and excretion of sodium lauriminodipropionate were not found, a possible metabolic scheme was described based on features of a structure activity relationship (SAR) assessment (see Scheme 1).According to the assessment, sodium lauriminodipropionate is likely to be metabolized by glucuronidation and/or N-dealkylation. Glucuronide products are known to be rapidly excreted and not likely to be biologically active. However, while this reaction is conceivable, it is rare for carboxylic acids to be glucuronidated.N-Dealkylation products are usually dietary chemicals, such as straight chain fatty acids, that undergo intermediary metabolism. (The CIR Expert Panel has concluded that lauric acid and other straight chain fatty acids and related ingredients are safe for use in cosmetic products.9-11) In this scheme, the tertiary amine group of sodium lauriminodipropionate may undergo oxidative N-dealkylation to form 3,3’-azanediyldipropanoic acid, lauric acid,and/or 3-(dodecylamino)propanoic acid. Other N-dealkylation products may be laurylamine and/or malonic acid.This reaction is nearly always catalyzed by cytochrome P450s. The mechanism involves hydrogen abstraction and hydroxylation at a carbon atom alpha to the nitrogen atom.In this scheme, sodium lauriminodipropionate may also undergo C-hydroxylation reactions on the alkyl chain. The products of this reaction may be 3,3’-(11-hydroxydodecylazanediyl)dipropanoic acid and 3,3’-(12-hydroxydodecylazanediyl)dipropanoic acid. On the longer alkyl chain, hydroxylation at the methylene group and hydroxylation at the terminal methyl group may be favorable.Dermal – Non-Human SODIUM LAURIMINODIPROPIONATE In acute dermal studies, no deaths or adverse reactions were observed in rabbits treated with 6.8 g/kg or 10.2 g/kg sodium lauriminodipropionate (10% active).From the Final Report on the Safety Assessment of Sodium Lauriminodipropionate.Oral – Non-Human SODIUM LAURIMINODIPROPIONATE The oral LD50 in albino mice treated with sodium lauriminodipropionate, 16% solids and pH 7.0, was estimated to be 17.8 ml/kg.From the Final Report on the Safety Assessment of Sodium Lauriminodipropionate.Dermal – Non-Human SODIUM LAURIMINODIPROPIONATE The percutaneous toxicity potential of sodium lauriminodipropionate was evaluated in a 91 day study in New Zealand White rabbits.12 There were 5 male and 5 female rabbits in the test group that received 2 ml/kg/day of 20% w/w solution in distilled water of 10.5% sodium lauriminodipropionate (35% of a 30% solution) in a foaming face wash. A control group of 5 male and 5 female rabbits received distilled water. The rabbits received the treatment or the control solutions daily, 5 days/week, to clipped, intact dorsal skin. The animals were checked twice daily for mortality and once daily for clinical signs of toxicity. Body weights were measured prior to study commencement, once a week during treatment, at 28 days, and at study termination. Hematology parameters were measured prior to study commencement and at study termination. All animals were killed at the end of the treatment period and underwent macro- and microscopic examination. Absolute and relative weights of the liver and kidney were determined.Dermal irritation was observed in the test group, which included slight to moderate erythema (starting on day 7), slight to moderate edema (starting on day 7), and slight to marked desquamation (days 7-14). There were no signs of systemic toxicity. All animals survived until study termination. Body weights of the treated animals were comparable to the control animals. There were no treatment-related changes to hematology parameters or differences in organ weights when compared to controls. No macroscopic or microscopic changes that suggested systemic toxicity were observed at necropsy in any of the animals. This study concluded that while sodium lauriminodipropionate did not cause dermal toxicity, it was a dermal irritant.DISODIUM LAURIMINODIPROPIONATE In a study of a hair dye formulation containing 1.5% disodium lauriminodipropionate, no systemic effects were observed in New Zealand white rabbits after topical application twice weekly for 13 weeks.SODIUM LAURIMINODIPROPIONATE While there is no information available in the literature on the reproductive and developmental toxicity of sodium lauriminodipropionate, a SAR assessment was conducted that considered the potential metabolites of this ingredient (see Figure 1).8 Sodium lauriminodipropionate is likely to be metabolized by glucuronidation and/or Ndealkylation. The specific glucuronide product for sodium lauriminodipropionate has not been assessed for reproductive or developmental toxicity, however, glucuronides in general have not been classified as developmental or reproductive hazards.Among the products of N-dealkylation, straight-chain fatty acids, such as lauric acid, have been evaluated for reproductive and developmental hazards and no adverse effects have been reported.8,14 The CIR Expert Panel has reviewed several straight-chain fatty acids, including lauric acid, and related ingredients, including plant-derived fatty acid oils, and has found these ingredients to be safe for use in cosmetic products.While the possible N-dealkylation product laurylamine has not been tested for reproductive toxicity, a similar compound, oleylamine has been assessed and found to not affect development in rats and rabbits, even at maternally toxic oral doses.The developmental NOAEL was 80 mg/kg/day for rats and 30 mg/kg/day for rabbits in these studies. Another possible N-dealkylation product, a mixture of tallow alkyl amines, did produce a decrease in offspring weight and a decrease in fertility at severely toxic levels, but this can be attributed to being secondary to the toxicity. Malonic acid may also be a product of N-dealkylation. This chemical, which has been previously assessed by the CIR Expert Panel and determined to be safe for use in cosmetic products, has been evaluated for developmental toxicity in rats.15 At concentration of 9 or 12% malonate in feed (approximate dosage for 9% malonate was 4.5 g/kg/day), low toxicity was observed in dams and fetuses.16 A few malformations were reported for 4.5 g/kg/day, but these incidences were within historical control ranges, and this dose was considered the NOAEL for developmental toxicity.Deriphat 160 C is an amphoteric surfactant based on sodium N-lauryl-betaiminodipropionate.Deriphat 160 C is a clear yellowish liquid at room temperature and is prone to sedimentation at low temperatures. Deriphat 160 C should be stored indoors in a dry piace.The storage temperature should not be allowed to fall substantially below 20 °C.The congealing point of Deriphat 160 C also need to be taken into account Liquid that has solidified or that shows signs of sedimentation should be heated to 50- 70 °C and homogenized before it is processed. Please mix sufficiently prior to use.Solubility of Deriphat 160 C (10% at 23 °C) In various aqueous solutions of Deriphat 160 C, no impact on viscosity is noticeable. Deriphat 160 C is an amphoteric surfactant for cleaners. It exhibits very good foaming power in hard and soft water.Description Deriphat 160 C is a unique, multi-functional amphoteric surfactant. It can function as a foamer, cleaning agent, corrosion inhibitor, and a hydrotrope. The isoelectric point is 2.4 to 4.2.Benefits:Easy to formulate ultra concentrates Stable in strong acid and alkaline solutions Lasting corrosion inhibition Foam not effected by pH or electrolytes Effective hydrotrope Good emulsifier at low concentrations Listed on CleanGredients approved DfE Solubilizer for cationic germicides Deriphat 160 C is especially valuable for its ability to produce and maintain stable emulsions at extremes of pH. It will function effectively at highly alkaline pH where most cationic, non-ionic and anionic emulsifiers are ineffective.Product: sodium lauriminodipropionate 30% (DERIPHAT 160 C, BASF) CAS No.: 14960-06-6 Deriphat 160 C DERIPHAT 160 C is an amphoteric surfactant for cleaners which is sold as 30% liquid. The product exhibits very good foaming power in hard and soft water. Its stability over a broad pH range allows its use in acidic and alkaline formulations. DERIPHAT® 160 C can be combined with cationic surfactants which are often used as bactericides for disinfectants. DERIPHAT® 160 C is a strong hydrotrope with excellent water solubility over a broad pH range even when high electrolyte concentration is present. DERIPHAT® 160 C is compatible with other common nonionic, anionic and cationic surfactants.Value Excellent hydrotrope, providing good cleaning, wetting and corrosion inhibition.It exhibits very good foaming power in hard and soft water. 3655-00-3 (26256-79-1, 3655-00-3) Deriphat · Deriphat 160c · Deriphat 160 Cadmium is a toxic and hazardous trace metal that has become a serious environmental pollutant since industrialization and intensive farming began in late 19th century. Although there are many established wet-chemical and instrumental methods for qualitative and quantitative determination of cadmium, most involve the formation of the Cd-dithizone complex in the presence of the highly toxic potassium cyanide which is then extracted into carcinogenic chlorinated organic solvents such as chloroform or carbon tetrachloride. The main purpose of this study was to see if a sensitive, simple, quick spectro-chemical method that utilizes safer and less toxic chemicals for cadmium analysis using dithizone could be developed. The results found so far are promising and indicate that in the presence of a chelating surfactant such as Deriphat-160C, the cadmium-dithizone complex in alkaline aqueous medium remains soluble and obeys Beers law in the micro molar Cd concentration range studied. The solutions prepared for spectroscopic measurement did not require KCN nor was it necessary to extract the complex in to chlorinated organic solvents. compound in Deriphat 160C) Deriphat 160 C. 0.38% 0.38% 0.38% 24.3% In this example, Deriphat 160C® could not be dissolved in 29.6% K-glyphosate (aq.) if the concentration of Deriphat 160C was >0.38% (#1 in the table). With the addition of 0.37% C6-9 dimethylamidopropylamine, the hazy formulation became a clear solution (#2). #3 showed that pH effect is not the main reason for the dissolution of the insoluble species in K-glyphosate formulation. This concentration of surfactant in #1 was much too low to offer any benefit to glyphosate efficacy. In order for a surfactant to offer consistent benefit to glyphosate efficacy, the surfactant concentration typically has to be about greater than 7%. However, more than 24.3% Deriphat could be dissolved in the 29.6% K-glyphosate (aq.) if 2% C6-C9 dimethyamidopropylamine was added as the compatibility agent (#4).SODIUM LAURIMINODIPROPIONATE SODIUM LAURIMINODIPROPIONATE is classified as :Antistatic Cleansing Foaming Foam boosting Hair conditioning Surfactant Cosmetics Ingredients containing SODIUM LAURIMINODIPROPIONATE Sodium Lauriminodipropionate and Sodium Lauraminopropionate are sodium salts of substituted propionic acid. Sodium Lauriminodipropionate may be used in the formulation of hair conditioners, hair dyes, bath products and other cleansing products.DISODIUM LAURIMINODIPROPIONATE In a study of a hair dye formulation containing 1.5% disodium lauriminodipropionate, no embryotoxic or teratogenic effects were observed in Charles River CD rats that were exposed to the formulation on days 1, 4, 7, 10, 13, 16, and 19 of gestation.The mutagenicity potential of 30% sodium lauriminodipropionate was assessed in an Ames test with Salmonella typhimurium strains TA98, TA100, TA1535, TA1537, and TA1538.17 The assay was performed with and without S9 metabolic activation. The concentration ranges tested were 0.003-10 μl/plate with S9 and 0.01-1.0 μl without S9. Because of lack of toxicity in test strains TA98, TA1535, and TA1538 without S9, additional assays were run using concentration ranges of 0.33-20 μl/plate. No positive responses were observed in any of the test strains, with or without S9. The vehicle control water and the positive controls 2-nitrofluorene, 2-aminoanthracene,sodium azide, and ICR-191 yielded expected results. It was concluded that sodium lauriminodipropionate was not mutagenic in this Ames test.A Chinese hamster ovary (CHO) cell assay was performed to assess the potential of 30% sodium lauriminodipropionate to induce chromosome aberrations.18 Following a range finding study, the concentration ranges for the 8 h incubation study were 0.21, 0.28, and 0.38 μl/ml without S9 and 0.48, 0.63, and 0.84 μl/ml with S9. In the 12 h incubation study, the concentration ranges were 0.28, 0.38, and 0.50 μl/ml without S9 and 0.63,0.84, and 1.13 μl/ml with S9. Relative cloning efficiency at the highest doses in the 8 h study were 34% and 70% without and with S9, respectively, while in the 12 h study, the values were 1% and 38% without and with S9, respectively. The controls, which were water, untreated cells, cyclophosphamide (CP), and triethylenemelamine (TEM), yielded expected results. The test material did not induce significant chromosome aberrations in either incubation period, with or without S9 metabolic activation. It was concluded that sodium lauriminodipropionate was not clastogenic.Sodium lauriminodipropionate, 10% solids, had a mean primary irritation index (PII) of 3.04/8 and was considered corrosive to the skin of rabbits due to eschar formation. In another study, sodium lauriminodipropionate, 16% solids at pH 7.0, was a moderate irritant to rabbit skin, with a PII of 2.17. A solution of sodium lauriminodipropionate, 10% solids, was classified as mildly irritating to the eyes of rabbits without rinsing, and practically nonirritating with rinsing. Another solution of sodium lauriminodipropionate, 16% solids at pH 7.0, was a moderate irritant.From the Final Report on the Safety Assessment of Sodium Lauriminodipropionate.No sensitization was observed in guinea pigs injected intracutaneously with 0.1% sodium lauriminodipropionate.From the Final Report on the Safety Assessment of Sodium Lauriminodipropionate.SODIUM LAURIMINODIPROPIONATE Sodium lauriminodipropionate was reported to be “practically nontoxic” to the skin and “minimally irritating” upon skin contact. It was also reported to be “minimally irritating” to the eye. Sodium lauriminodipropionate was “practically nontoxic” upon ingestion.From the Final Report on the Safety Assessment of Sodium Lauriminodipropionate.A human repeat insult patch test (HRIPT) of the potential of 2.2% sodium lauriminodipropionate (7.34% of 30% solution) to induce contact sensitization was conducted using 104 subjects.In another HRIPT, the potential of 3.5% active sodium lauriminodipropionate (11.67% of a 30% solution) to induce contact sensitization was studied in 116 subjects.2 Current FDA VCRP data indicate that sodium lauriminodipropionate is used in 10 cosmetic formulations,mainly in hair conditioners. The current concentration of use for sodium lauriminodipropionate is 0.05% in hair conditioners. Disodium lauriminodipropionate has been reported to have uses in 2 face and neck preparations. No uses are reported for lauriminodipropionic acid. No use concentrations were reported for the disodium salt or the acid.Sodium lauriminodipropionate has applications in heavy-duty alkaline cleaners, corrosion inhibitors,leather cleaners, and acid cleaners. The Environmental Protection Agency (EPA) has ruled that the sodium and potassium salts of N-alkyl (C8-C18)-beta-iminodipropionic acid do not need a maximum permissible level when they are used as inert ingredients in pesticide formulations for pre- and post-harvest applications in food crops.A possible metabolic scheme based on features of a structure activity relationship (SAR) assessment suggested that sodium lauriminodipropionate is likely to be metabolized by glucuronidation and/or N-dealkylation. In studies of 10% active solutions of sodium lauriminodipropionate, the oral LD50 for rats was 31.3 g/kg,and the dermal LD50 was greater than 10.2 g/kg; the oral LD50 for mice of a 16% solids solution was estimated as 17.8 ml/kg.A 91 day study in rabbits that received 20% w/w solution in distilled water of 10.5% sodium lauriminodipropionate (35% of a 30% solution) concluded that while sodium lauriminodipropionate did not cause dermal or systemic toxicity, it was a dermal irritant. No systemic effects were observed in rabbits that received topical applications of a hair dye formulation containing 1.5% disodium lauriminodipropionate for 13 weeks.A structure activity assessment conducted for potential metabolites of sodium lauriminodipropionate concluded that the metabolites were not developmental or reproductive toxicants. A developmental study in rats on a hair dye formulation containing 1.5% disodium lauriminodipropionate did not observe embryotoxic or teratogenic effects. Sodium lauriminodipropionate was not mutagenic in an Ames test, nor was it clastogenic in a CHO cell assay.Sodium lauriminodipropionate at 10% active solution was severely irritating to the skin of rabbits. Sodium lauriminodipropionate at 16% solids was a moderate irritant to rabbit skin.Sodium lauriminodipropionate was irritating to the eyes of rabbits. Two shampoo formulations containing 3.56% active sodium lauriminiodipropionate did not cause ocular lesions or induce a significant increase in albumin levels in tears in humans. Minimal observations of stinging or dryness sensations were made in both phases of the study.There was no evidence of sensitization to sodium lauriminodipropionate in studies with guinea pigs. A foaming face wash containing 2.2% active sodium lauriminodipropionate and a shampoo formulation containing 3.5% active sodium lauriminodipropionate did not cause delayed contact hypersensitivity in HRIPT studies.A safety assessment for sodium lauriminodipropionate and sodium lauraminopropionate was published by in 1997 with the conclusion that the available data were insufficient to support their safety in cosmetics. The Expert Panel reopened the final report on sodium lauriminodipropionate based on new data and determined that the report should also address the safety of lauriminopropionic acid and disodium lauriminodipropionate.The Panel reaffirmed the conclusion of insufficient data for sodium lauraminopropionate.The CIR Expert Panel considered that the available single dose and repeated dose animal studies, including reproductive and developmental toxicity studies, were supportive of the safety of sodium lauriminodipropionate.The Expert Panel noted the absence of carcinogenicity data, but considered that that data demonstrating that sodium lauriminodipropionate was not mutagenic or clastogenic in in vitro genotoxicity studies were adequate to support the safety of these ingredients. The Cosmetic Ingredient Review Expert Panel assessed the safety of lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate as used in cosmetics. These ingredients function in cosmetics as hair-conditioning agents and surfactant-cleansing agents. The Panel reviewed relevant animal and human data related to the safety of these ingredients in cosmetics. The Panel concluded that lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate are safe as cosmetic ingredients in the present practices of use and concentration.The Cosmetic Ingredient Review Expert Panel assessed the safety of lauriminodipropionic acid, sodium lauriminodipropionate,and disodium lauriminodipropionate as used in cosmetics. These ingredients function in cosmetics as hair-conditioning agents and surfactant-cleansing agents. The Panel reviewed relevant animal and human data related to the safety of these ingredients in cosmetics. The Panel concluded that lauriminodipropionic acid, sodium lauriminodipropionate, and disodium lauriminodipropionate are safe as cosmetic ingredients in the present practices of use and concentration.Sodium lauriminodipropionate is the sodium salt of a substituted propionic acid that is used as a surfactant, a hair-conditioning agent, and an antistatic agent in cosmetic formulations. In a safety assessment for sodium lauriminodipropionate and sodium lauraminopropionate published by the Cosmetic Ingredient Review (CIR) in 1997,1 the CIR Expert Panel concluded that the available data were insufficient to support safety of both the ingredients for use in cosmetics.Now, data that support the safety of sodium lauriminodipropionate as used in cosmetics are available. Because of thechemical similarities to sodium lauriminodipropionate, the CIRExpert Panel determined that the newly available data may beextrapolated to the parent compound, lauriminodipropionicacid, and to the disodium salt.No new safety test data were available for sodium lauraminopropionate; therefore, CIR Expert Panel did not reopen thefinal report to include this ingredient and reaffirmed the conclusion of insufficient data for sodium lauraminopropionate.Deriphat 160C is a polyfunctional surfactant for hard surface cleaners and I&I applications with excellent degreasing abilities enhancing in addition the solubility of inorganic salts and organic additives such as fragrances and cationic preservatives. Deriphat 160 is also providing corrosion inhibition and is stable under highly acidic and highly alkaline conditions. Its affinity to hard surfaces allows long lasting effects. Deriphat 160 C is especially recommended for disinfectant cleaners and cleaners for contact with metal including kitchen degreasers, bathroom cleaners and institutional cleaners.
TR
Deriphat 160 c IUPAC Ad sodyum; 3- [2-karboksietil (dodesil) amino] propanoat
Deriphat 160 c InChI InChI = 1S / C18H35NO4.Na / c1-2-3-4-5-6-7-8-9-10-11-14-19 (15-12-17 (20) 21) 16- 13-18 (22) 23; / h2-16H2,1H3, (H, 20,21) (H, 22,23); / q; + 1 / p-1
Deriphat 160 c InChI Anahtar LLKGTXLYJMUQJX-UHFFFAOYSA-M
Deriphat 160 c Kanonik SMILES CCCCCCCCCCCCN (CCC (= O) O) CCC (= O) [O -]. [Na +]
Deriphat 160 c Moleküler Formül C18H34NNaO4
Deriphat 160 c CAS 14960-06-6
Deriphat 160 c Kullanmdan Kaldrlm CAS 195603-51-1
Deriphat 160 c Avrupa Topluluu (EC) Numaras 239-032-7
Deriphat 160 c UNII 7G447D0DH9
Deriphat 160 c DSSTox Madde Kimlii DTXSID7041207
Deriphat 160 c Fiziksel Tanm Sv
Deriphat 160 c Tüketici Kullanm Alanlar Temizlik ve mefruat bakm ürünleri
Deriphat 160 c Tehlike Snflar ve Kategorileri Skin Irrit. 2 (% 71.14) Göz Hsr. 1 (% 59.4) Eye Irrit. 2 (% 40.6)
Deriphat 160 c Moleküler Arlk 351,5 g / mol
Deriphat 160 c Hidrojen Ba Donör Says 1
Deriphat 160 c Hidrojen Ba Alcs Says 5
Deriphat 160 c Döndürülebilir Tahvil Says 17
Deriphat 160 c Tam Kütle 351.238553 g / mol
Deriphat 160 c Monoizotopik Kütle 351.238553 g / mol
Deriphat 160 c Topolojik Polar Yüzey Alan 80,7 Ų
Deriphat 160 c Ar Atom Says 24
Deriphat 160 c Resmi Yük 0
Deriphat 160 c Karmaklk 313
Deriphat 160 c zotop Atom Says 0
Deriphat 160 c Tanml Atom Stereocenter Says 0
Deriphat 160 c Tanmsz Atom Stereocenter Says 0
Deriphat 160 c Tanml Bond Stereocenter Says 0
Deriphat 160 c Tanmsz Ba Stereocenter Says 0
Deriphat 160 c Kovalent Bal Birim Says 2
Deriphat 160 c Bileik Kanonikletirilmitir Evet
Deriphat 160 C, sodyum N-lauril-betaiminodipropionat bazl bir amfoterik yüzey aktif maddedir. Deriphat 160 C, oda scaklnda berrak sarms bir svdr ve düük scaklklarda çökelmeye eilimlidir. Deriphat 160 C kuru bir yerde iç mekanlarda saklanmaldr. Depolama scaklnn önemli ölçüde 20 ° C’nin altna dümesine izin verilmemelidir Deriphat 160 C’nin donma noktas da dikkate alnmaldr. sedimantasyon ilenmeden önce 50- 70 ° C’ye stlmal ve homojenize edilmelidir. Lütfen kullanmadan önce yeterince kartrn. Deriphat 160 C’nin Çözünürlüü (23 ° C’de% 10) Deriphat 160 C’nin çeitli sulu çözeltilerinde, viskozite üzerinde herhangi bir etki fark edilmez. Deriphat 160 C, temizleyiciler için amfoterik bir yüzey aktif maddedir. Sert ve yumuak suda çok iyi köpürme gücü gösterir. Tanm Deriphat 160 C, benzersiz, çok fonksiyonlu amfoterik bir yüzey aktif maddedir. Köpürtücü, temizlik maddesi, korozyon önleyici ve hidrotrop olarak ilev görebilir. zoelektrik noktas 2,4 ila 4,2’dir Yararlar: Ultra konsantreleri formüle etmek kolaydr Güçlü asit ve alkali solüsyonlarda kararldr Kalc korozyon inhibisyonu Köpük pH veya elektrolitlerden etkilenmez Etkili hidrotrop Düük konsantrasyonlarda iyi emülgatör CleanGredients onayl DfE Çözücüde katyonik mikrop öldürücüler Deriphat 160 listelenmitir C, ar pH deerlerinde stabil emülsiyonlar üretme ve muhafaza etme kabiliyeti açsndan özellikle deerlidir. Katyonik, iyonik olmayan ve anyonik emülgatörlerin çounun etkisiz olduu yüksek alkali pH’ta etkin bir ekilde çalacaktr. % 30 sv olarak satlan temizleyiciler için amfoterik bir yüzey aktif madde. Ürün sert ve yumuak suda çok iyi köpürme gücü sergiler. Geni bir pH aral üzerindeki stabilitesi, asidik ve alkali formülasyonlarda kullanmna izin verir. DERIPHAT® 160 C, genellikle dezenfektanlar için bakterisit olarak kullanlan katyonik yüzey aktif maddelerle birletirilebilir. DERIPHAT 160 C, yüksek elektrolit konsantrasyonu mevcut olduunda bile geni bir pH aralnda mükemmel suda çözünürlüü olan güçlü bir hidrotroptur. DERIPHAT® 160 C dier yaygn noniyonik, anyonik ve katyonik yüzey aktif maddelerle uyumludur.Deer Mükemmel hidrotrop, iyi temizleme, slatma ve korozyon önleme salar. Sert ve yumuak suda çok iyi köpürme gücü gösterir. 3655-00-3 (26256-79-1, 3655-00-3) Deriphat 160 c · Deriphat 160c · Deriphat 160 Kadmiyum, sanayileme ve youn tarm 19. yüzyln sonlarnda baladndan beri ciddi bir çevre kirleticisi haline gelen toksik ve tehlikeli bir eser metaldir . Kadmiyumun kalitatif ve kantitatif tayini için birçok yerleik slak-kimyasal ve enstrümantal yöntem olmasna ramen, çou yüksek derecede toksik potasyum siyanür varlnda Cd-ditizon kompleksinin oluumunu içerir ve daha sonra kloroform gibi kanserojen klorlu organik çözücülere ekstrakte edilir. veya karbon tetraklorür. Bu çalmann temel amac, ditizon kullanarak kadmiyum analizi için daha güvenli ve daha az toksik kimyasallar kullanan hassas, basit, hzl bir spektro-kimyasal yöntemin gelitirilip gelitirilemeyeceini görmekti. imdiye kadar bulunan sonuçlar umut vericidir ve Deriphat-160C gibi bir elatlayc yüzey aktif maddenin varlnda alkali sulu ortamdaki kadmiyum-ditizon kompleksinin çözülebilir kaldn ve incelenen mikro molar Cd konsantrasyon aralnda Beers yasasna uyduunu göstermektedir. Spektroskopik ölçüm için hazrlanan çözeltiler, KCN gerektirmedi ve kompleksi klorlu organik çözücülere ekstrakte etmek gerekli deildi. Deriphat 160C’deki bileik) Deriphat 160 C.% 0.38% 0.38% 0.38% 24.3 Bu örnekte, Deriphat 160C konsantrasyonu>% 0.38 (#) ise Deriphat 160C®% 29.6 K-glifosat (sulu) içinde çözülemez Tabloda 1). % 0.37 C6-9 dimetilamidopropilamin ilavesiyle bulank formülasyon berrak bir çözelti (# 2) haline geldi. # 3, pH etkisinin, çözünmeyen türlerin K-glifosat formülasyonunda çözünmesinin ana nedeni olmadn gösterdi. # L’deki bu yüzey aktif madde konsantrasyonu, glifosat etkinliine herhangi bir fayda salamak için çok düüktü.Bir yüzey aktif maddenin glifosat etkinliine tutarl bir fayda salamas için, yüzey aktif madde konsantrasyonunun tipik olarak yaklak% 7’den fazla olmas gerekir. Bununla birlikte, uyumluluk ajan olarak% 2 C6-C9 dimetilamidopropilamin eklendiyse (# 4)% 29,6 K-glifosat (aq.) çinde% 24,3’den fazla Deriphat 160 c çözünebilir. SODYUM LAURIMINODIPROPIONATE SODIUM LAURIMINODIPROPIONATE u ekilde snflandrlr: Antistatik Temizleme Köpük artrc Saç ekillendirici Sürfaktan Kozmetikler SODYUM LAURIMINODIPROPIONATE Sodyum Lauriminodipropionate ve Sodyum Lauraminopropionate içeren içerikler, ikame edilmi propionik asidin sodyum tuzlardr. Sodyum Lauriminodipropionate, saç kremleri, saç boyalar, banyo ürünleri ve dier temizlik ürünlerinin formülasyonunda kullanlabilir. Sodyum Lauriminodipropionate, statik elektrik oluumunu önleyen veya inhibe eden bir anti-statik ajan olarak ilev görür. Sodyum lauriminodipropionat beta-alanin, N – (2-karboksietil) -n-dodesil-, sodyum tuzu (1: 1) GENEL ADI: Sodyum Lauriminodipropionate% 30 Lauriminodipropionic Acid, Sodium Lauriminodipropionate ve Disodyum Lauriminodipropionate olarak Cosodium Lauriminodipropionate function as lauriminodipropionate ve disodyum lauriminodipropionate ve disodyum lauriminodipropionate kozmetik formülasyonlarda saç bakm maddeleri ve yüzey aktif madde temizleme maddeleri. CIR Uzman Paneli, kozmetikte bu bileenlerin güvenlii ile ilgili hayvan ve insan verilerini inceledi. Panel, lauriminodipropionic asit, sodyum lauriminodipropionate ve disodyum lauriminodipropionate’in mevcut kullanm ve konsantrasyon uygulamalarnda kozmetik bileenler olarak güvenli olduu sonucuna varmtr. Sodyum lauriminodipropionat, bir yüzey aktif madde, bir saç bakm maddesi olarak kullanlan sübstitüe edilmi bir propiyonik asidin sodyum tuzudur. kozmetik formülasyonlarda antistatik bir ajan. 1997’de Cosmetic Ingredient Review (CIR) tarafndan yaynlanan sodyum lauriminodipropionate ve sodyum lauraminopropionate için bir güvenlik deerlendirmesinde, CIR Expert Panel mevcut verilerin kozmetiklerde kullanm için her iki bileenin güvenliini desteklemek için yetersiz olduu sonucuna varmtr. Ek yaynlanmam veriler artk mevcuttur. kozmetikte kullanlan sodyum lauriminodipropionatn güvenliini destekleyen. Sodyum lauriminodipropionata kimyasal benzerliklerinden dolay, CIR Uzman Paneli, yeni mevcut verilerin ana bileik, lauriminodipropionik asit ve disodyum tuzuna ekstrapole edilebileceini de deerlendirdi.Sodyum lauraminopropionat hakknda yeni veri bulunmadndan, CIR Uzman Paneli bu bileeni içerecek ekilde nihai raporu yeniden açmad ve sodyum lauraminopropionat için yetersiz veri olduu sonucunu yeniden dorulad. Sodyum lauriminodipropionat üretimindeki ana safszlk sodyum akrilattr. Balangç materyali olan dodesilamin ile ilikili az miktarda dodesil zinciri bileikleri olabilir. ayrca mevcut olun. Toplam safszlklar, satld gibi üründe tipik olarak% 2’den daha düük seviyelerde bulunur. Ticari ürünün parti numunelerinde dodesilamin, poliakrilik asit veya sodyum poliakrilat tespit edilmemitir. Sodyum lauriminodipropionat üretiminde eser miktarda sodyum lauraminopropionat oluabilir. Saç bakm ajanlar olarak lauriminodipropionic asit, sodyum lauriminodipropionat ve disodyum lauriminodipropionat, kozmetik formülasyonlarda sürfaktan temizleme ajanlar, monosodyum ve disodyum tuzlar da antistatik ajan olarak kullanlmaktadr. ve monosodyum tuzu, yüzey aktif madde-köpük güçlendirici olarak kullanlr. Tablo 3, sodyum lauriminodipropionat için geçmi ve güncel ürün formülasyon verilerini sunar. Gönüllü Kozmetik Kayt Programnn bir parças olarak endüstri tarafndan Gda ve laç Dairesi’ne (FDA) salanan bilgilere göre (VCRP), sodyum lauriminodipropionat, ilk güvenlik deerlendirmesi srasnda toplam 23 kozmetik formülasyonda kullanlmtr. Bir endüstri aratrmas% 1-10 arasnda bir kullanm konsantrasyon aral bildirmitir.1 u anda, VCRP verileri, sodyum lauriminodipropionatn 10 yars saç kremi olan kozmetik formülasyonlar.Kiisel Bakm Ürünleri Konseyi tarafndan yaplan güncel kullanm konsantrasyonlar aratrmasnda, saç kremlerinde sodyum lauriminodipropionat% 0,05 konsantrasyonda kullanlmaktadr.u anda, VCRP verileri disodyum lauriminodipropionatn her ikisi de yüz olan 2 kozmetik formülasyonda kullanldn göstermektedir. Lauriminodipropionic asit için herhangi bir kullanm bildirilmemitir.Sodyum lauriminodipropionate tarafndan yürütülen mevcut kullanm konsantrasyonu aratrmasnda asit veya disodyum tuzu için kullanm konsantrasyonlar bildirilmemitir. Sodyum Lauriminodipropionate Güvenlik Deerlendirmesine likin Nihai Rapordan SODYUM LAURIMINODIPROPIONATE Sodyum lauriminodipropionatn absorpsiyonu, dalm, metabolizmas ve atlm hakknda özel bilgiler bulunmazken, aadaki özelliklere göre olas bir metabolik ema tanmlanmtr. yap aktivite ilikisi (SAR) deerlendirmesi (ler) ee ema 1). Deerlendirmeye göre, sodyum lauriminodipropionatn glukuronidasyon ve / veya N-dealkilasyon ile metabolize edilmesi muhtemeldir. Glukuronid ürünlerinin hzla atld ve muhtemelen biyolojik olarak aktif olmad bilinmektedir. Bununla birlikte, bu reaksiyon mümkün olsa da, karboksilik asitlerin glukuronide olmas nadirdir. N-Dealkilasyon ürünleri genellikle ara metabolizmaya giren düz zincirli ya asitleri gibi diyet kimyasallardr. (CIR Uzman Paneli, laurik asit ve dier düz zincirli ya asitleri ve ilgili bileenlerin kozmetik ürünlerde kullanm için güvenli olduu sonucuna varmtr.9-11) Bu emada, sodyum lauriminodipropionatn üçüncül amin grubu, olumak için oksidatif N-dealkilasyondan geçebilir. 3,3′-azandiildipropanoik asit, laurik asit ve / veya 3- (dodesilamino) propanoik asit. Dier N-dealkilasyon ürünleri laurilamin ve / veya malonik asit olabilir. Bu reaksiyon hemen hemen her zaman sitokrom P450’ler tarafndan katalize edilir. Mekanizma, bir karbon atomunda alfa azot atomunda hidrojen soyutlamasn ve hidroksilasyonunu içerir.Bu emada, sodyum lauriminodipropionat, alkil zinciri üzerinde C-hidroksilasyon reaksiyonlarna da girebilir. Bu reaksiyonun ürünleri 3,3 ’- (11-hidroksidodesilazandiil) dipropanoik asit ve 3,3’ – (12-hidroksidodesilazandiil) dipropanoik asit olabilir. Daha uzun alkil zincirinde, metilen grubunda hidroksilasyon ve terminal metil grubunda hidroksilasyon uygun olabilir. Termal – nsan D SODYUM LAURIMINODIPROPIONATE Akut dermal çalmalarda, 6.8 g / kg ile tedavi edilen tavanlarda herhangi bir ölüm veya advers reaksiyon gözlenmemitir. 10,2 g / kg sodyum lauriminodipropionat (% 10 aktif) Sodyum Lauriminodipropionate Güvenlik Deerlendirmesine likin Nihai Rapordan Oral – nsan D SODYUM LAURIMINODIPROPIONATE Sodyum lauriminodipropionate,% 16 kat ve pH 7.0 ile tedavi edilen albino farelerde oral LD50 Sodyum Lauriminodipropionate Güvenlik Deerlendirmesine likin Nihai Rapordan Deri – nsan D SODYUM LAURIMINODIPROPIONATE Sodyum lauriminodipropionatn perkütan toksisite potansiyeli Yeni Zelanda Beyaz tavanlarnda 91 günlük bir çalmada deerlendirilmitir.12 % 10.5 sodyum lauriminodipropion damtlm suda 2 ml / kg / gün% 20 w / w çözelti alan test grubundaki 5 erkek ve 5 dii tavan köpüklü bir yüz ykamada yedik (% 30 solüsyonun% 35’i). 5 erkek ve 5 dii tavandan oluan bir kontrol grubuna damtlm su verildi. Tavanlar, kesilmi, salam srt derisine haftada 5 gün, günlük olarak tedavi veya kontrol solüsyonlarn aldlar. Hayvanlar mortalite açsndan günde iki kez ve klinik toksisite iaretleri açsndan günde bir kez kontrol edildi. Vücut arlklar, çalmann balamasndan önce, tedavi srasnda haftada bir, 28 günde ve çalmann bitiminde ölçüldü. Hematoloji parametreleri çalmann balamasndan önce ve çalmann sonlandrlmasnda ölçüldü. Tedavi süresinin sonunda tüm hayvanlar öldürüldü ve makro ve mikroskobik incelemeye tabi tutuldu. Karacier ve böbrein mutlak ve nispi arlklar belirlendi.Test grubunda hafif ila orta derecede kzarklk (7. günden itibaren), hafif ila orta derecede ödem (7. günden itibaren) ve hafif ila belirgin deskuamasyon (7-14. Günler) içeren dermal tahri gözlendi. Sistemik toksisite belirtisi yoktu. Tüm hayvanlar çalmann sonlanmasna kadar hayatta kald. Muamele edilen hayvanlarn vücut arlklar, kontrol hayvanlar ile karlatrlabilir olmutur. Kontrollerle karlatrldnda, hematoloji parametrelerinde tedaviyle ilikili herhangi bir deiiklik veya organ arlklarnda farkllklar yoktu. Hayvanlarn hiçbirinde otopside sistemik toksisiteye iaret eden hiçbir makroskopik veya mikroskobik deiiklik gözlenmedi. Bu çalma, sodyum lauriminodipropionatn dermal toksisiteye neden olmad ancak dermal bir tahri edici olduu sonucuna varmtr. SODYUM LAURIMINODIPROPIONATE Literatürde sodyum lauriminodipropionatn üreme ve geliimsel toksisitesi hakknda hiçbir bilgi bulunmamakla birlikte, bu bileenin potansiyel metabolitlerini dikkate alan bir SAR deerlendirmesi yaplmtr (bkz. ekil 1) .8 Sodyum lauriminodipropionat muhtemelen glukuronidasyon ve / veya Ndealkilasyon ile metabolize edilebilir. Sodyum lauriminodipropiyonat için spesifik glukuronid ürünü üreme veya geliim toksisitesi açsndan deerlendirilmemitir, ancak genel olarak glukuronidler geliimsel veya üreme tehlikeleri olarak snflandrlmamtr. N-dealkilasyon ürünleri arasnda, laurik asit gibi düz zincirli ya asitleri , üreme ve geliimsel tehlikeler açsndan deerlendirilmitir ve herhangi bir yan etki bildirilmemitir.8,14 CIR Uzman Paneli, laurik asit dahil olmak üzere birkaç düz zincirli ya asidini ve bitkilerden türetilmi ya asidi yalar dahil ilgili bileenleri gözden geçirmitir ve Olas N-dealkilasyon ürünü olan laurilamin üreme toksisitesi için test edilmemi olsa da, benzer bir bileik olan oleyamin deerlendirilmi ve sçanlarda ve tavanlarda, hatta sçanlarda ve tavanlarda geliimi etkilemedii bulunmutur. Bu çalmalarda geliimsel NOAEL sçanlar için 80 mg / kg / gün ve tavanlar için 30 mg / kg / gün olmutur. Bir baka olas N-dealkilasyon ürünü, bir donya alkil aminleri karm, yavru arlnda bir azalma ve ciddi derecede toksik seviyelerde dourganlkta bir azalma meydana getirmitir, ancak bu, toksisiteye ikincil olarak atfedilebilir. Malonik asit ayrca bir N-dealkilasyon ürünü olabilir. Daha önce CIR Uzman Paneli tarafndan deerlendirilen ve kozmetik ürünlerde kullanm için güvenli olduu belirlenen bu kimyasal, sçanlarda geliimsel toksisite açsndan deerlendirilmitir.15 Yemde% 9 veya% 12 malonat konsantrasyonunda (yaklak% 9 dozaj) malonat 4.5 g / kg / gün idi), annelerde ve fetüslerde düük toksisite gözlendi.16 4.5 g / kg / gün için birkaç malformasyon bildirildi, ancak bu insidanslar tarihsel kontrol aralklar içindeydi ve bu doz, NOAEL olarak kabul edildi. geliimsel toksisite.Deriphat 160 C, sodyum N-lauril-betaiminodipropionat bazl bir amfoterik yüzey aktif maddedir. Deriphat 160 C, oda scaklnda berrak sarms bir svdr ve düük scaklklarda çökelmeye eilimlidir. Deriphat 160 C kuru bir yerde iç mekanlarda saklanmaldr. Depolama scaklnn önemli ölçüde 20 ° C’nin altna dümesine izin verilmemelidir Deriphat 160 C’nin donma noktas da dikkate alnmaldr. sedimantasyon ilenmeden önce 50- 70 ° C’ye stlmal ve homojenize edilmelidir. Lütfen kullanmadan önce yeterince kartrn. Deriphat 160 C’nin Çözünürlüü (23 ° C’de% 10) Deriphat 160 C’nin çeitli sulu çözeltilerinde, viskozite üzerinde herhangi bir etki fark edilmez. Deriphat 160 C, temizleyiciler için amfoterik bir yüzey aktif maddedir. Sert ve yumuak suda çok iyi köpürme gücü gösterir. Tanm Deriphat 160 C, benzersiz, çok fonksiyonlu amfoterik bir yüzey aktif maddedir. Köpürtücü, temizlik maddesi, korozyon önleyici ve hidrotrop olarak ilev görebilir. zoelektrik noktas 2,4 ila 4,2’dir Yararlar: Ultra konsantreleri formüle etmek kolaydr Güçlü asit ve alkali solüsyonlarda kararldr Kalc korozyon inhibisyonu Köpük pH veya elektrolitlerden etkilenmez Etkili hidrotrop Düük konsantrasyonlarda iyi emülgatör CleanGredients onayl DfE Çözücüde katyonik mikrop öldürücüler Deriphat 160 listelenmitir C, ar pH deerlerinde stabil emülsiyonlar üretme ve muhafaza etme kabiliyeti açsndan özellikle deerlidir. Katyonik, iyonik olmayan ve anyonik emülgatörlerin çounun etkisiz olduu yüksek alkali pH’ta etkin bir ekilde çalacaktr. % 30 sv olarak satlan temizleyiciler için amfoterik bir yüzey aktif madde. Ürün sert ve yumuak suda çok iyi köpürme gücü sergiler. Geni bir pH aral üzerindeki stabilitesi, asidik ve alkali formülasyonlarda kullanmna izin verir. DERIPHAT® 160 C, genellikle dezenfektanlar için bakterisit olarak kullanlan katyonik yüzey aktif maddelerle birletirilebilir. DERIPHAT® 160 C, yüksek elektrolit konsantrasyonu mevcut olduunda bile geni bir pH aralnda mükemmel suda çözünürlüü olan güçlü bir hidrotroptur. DERIPHAT® 160 C dier yaygn noniyonik, anyonik ve katyonik yüzey aktif maddelerle uyumludur.Deer Mükemmel hidrotrop, iyi temizleme, slatma ve korozyon önleme salar. Sert ve yumuak suda çok iyi köpürme gücü gösterir. 3655-00-3 (26256-79-1, 3655-00-3) Derifat · Deriphat 160c · Deriphat 160 Kadmiyum, sanayileme ve youn tarm 19. yüzyln sonlarnda baladndan beri ciddi bir çevre kirleticisi haline gelen toksik ve tehlikeli bir eser metaldir . Kadmiyumun kalitatif ve kantitatif tayini için birçok yerleik slak-kimyasal ve enstrümantal yöntem olmasna ramen, çou yüksek derecede toksik potasyum siyanür varlnda Cd-ditizon kompleksinin oluumunu içerir ve daha sonra kloroform gibi kanserojen klorlu organik çözücülere ekstrakte edilir. veya karbon tetraklorür. Bu çalmann temel amac, ditizon kullanarak kadmiyum analizi için daha güvenli ve daha az toksik kimyasallar kullanan hassas, basit, hzl bir spektro-kimyasal yöntemin gelitirilip gelitirilemeyeceini görmekti. imdiye kadar bulunan sonuçlar umut vericidir ve Deriphat-160C gibi bir elatlayc yüzey aktif maddenin varlnda alkali sulu ortamdaki kadmiyum-ditizon kompleksinin çözülebilir kaldn ve incelenen mikro molar Cd konsantrasyon aralnda Beers yasasna uyduunu göstermektedir. Spektroskopik ölçüm için hazrlanan çözeltiler, KCN gerektirmedi ve kompleksi klorlu organik çözücülere ekstrakte etmek gerekli deildi. Deriphat 160C’deki bileik) Deriphat 160 C.% 0.38% 0.38% 0.38% 24.3 Bu örnekte, Deriphat 160C konsantrasyonu>% 0.38 (#) ise Deriphat 160C®% 29.6 K-glifosat (sulu) içinde çözülemez Tabloda 1). % 0.37 C6-9 dimetilamidopropilamin ilavesiyle bulank formülasyon berrak bir çözelti (# 2) haline geldi. # 3, pH etkisinin, çözünmeyen türlerin K-glifosat formülasyonunda çözünmesinin ana nedeni olmadn gösterdi.# L’deki bu yüzey aktif madde konsantrasyonu, glifosat etkinliine herhangi bir fayda salamak için çok düüktü. Bir yüzey aktif maddenin glifosat etkinliine tutarl bir fayda salamas için, yüzey aktif madde konsantrasyonunun tipik olarak yaklak% 7’den fazla olmas gerekir. Bununla birlikte, uyumluluk ajan olarak% 2 C6-C9 dimetilamidopropilamin eklendiyse (# 4)% 29,6 K-glifosat (aq.) çinde% 24,3’den fazla Derifat çözünebilir. SODYUM LAURIMINODIPROPIONATE SODIUM LAURIMINODIPROPIONATE u ekilde snflandrlr: Antistatik Temizleme Köpük artrc Saç ekillendirici Sürfaktan Kozmetikler SODYUM LAURIMINODIPROPIONATE Sodyum Lauriminodipropionate ve Sodyum Lauraminopropionate içeren içerikler, ikame edilmi propionik asidin sodyum tuzlardr. Sodyum Lauriminodipropionate, saç kremleri, saç boyalar, banyo ürünleri ve dier temizlik ürünlerinin formülasyonunda kullanlabilir.% 1.5 disodyum lauriminodipropionat içeren bir saç boyas formülasyonu çalmasnda, Charles River CD sçanlarnda embriyotoksik veya teratojenik etkiler gözlenmedi. gebeliin 1, 4, 7, 10, 13, 16 ve 19. günlerinde formülasyona maruz braklanlar.% 30 sodyum lauriminodipropionatn mutajenite potansiyeli, Salmonella typhimurium sular TA98, TA100, TA1535, TA1537 ile bir Ames testinde deerlendirildi. ve TA1538.17 Test, S9 metabolik aktivasyonu ile ve olmadan gerçekletirildi. Test edilen konsantrasyon aralklar S9 ile 0.003-10 μl / plaka ve S9 olmadan 0.01-1.0 μl idi. S9’suz TA98, TA1535 ve TA1538 test sularnda toksisite eksiklii nedeniyle, 0.33-20 μl / plaka konsantrasyon aralklar kullanlarak ek testler yaplmtr. S9 içeren veya içermeyen test sularnn hiçbirinde pozitif yant gözlenmedi. Araç kontrol suyu ve pozitif kontroller 2-nitrofloren, 2-aminoantrasen, sodyum azit ve ICR-191 beklenen sonuçlar verdi. Bu Ames testinde sodyum lauriminodipropionatn mutajenik olmad sonucuna varld.% 30 sodyum lauriminodipropionatn kromozom anormalliklerini indükleme potansiyelini deerlendirmek için bir Çin hamsteri yumurtalk (CHO) hücre testi yapld.18 Bir aralk bulma çalmasnn ardndan, konsantrasyon aralklar 8 saatlik inkübasyon çalmas, S9 olmadan 0.21, 0.28 ve 0.38 μl / ml ve S9 ile 0.48, 0.63 ve 0.84 μl / ml idi. 12 saatlik inkübasyon çalmasnda, konsantrasyon aralklar S9 olmadan 0,28, 0,38 ve 0,50 μl / ml ve S9 ile 0,63,0,84 ve 1,13 μl / ml idi. 8 saatlik çalmadaki en yüksek dozlarda göreli klonlama etkinlii, S9 olmadan ve S9 ile srasyla% 34 ve% 70 iken, 12 saatlik çalmada, deerler S9 olmadan ve S9 ile srasyla% 1 ve% 38 idi. Su, ilenmemi hücreler, siklofosfamid (CP) ve trietilenemelamin (TEM) olan kontroller, beklenen sonuçlar verdi. Test materyali, S9 metabolik aktivasyonu ile veya olmakszn, her iki inkübasyon periyodunda da önemli kromozom anormalliklerine neden olmamtr. Sodyum lauriminodipropionatn klastojenik olmad sonucuna varld.% 10 kat olan sodyum lauriminodipropionat, 3.04 / 8 ortalama birincil tahri indeksine (PII) sahipti ve eskar oluumu nedeniyle tavanlarn derisini andrc olarak kabul edildi. Baka bir çalmada, pH 7.0’da% 16 kat olan sodyum lauriminodipropionat, 2.17 PII ile tavan derisi için orta derecede tahri ediciydi. % 10 kat olan bir sodyum lauriminodipropionat çözeltisi, durulamadan tavanlarn gözlerini hafifçe tahri edici ve durulamayla pratik olarak tahri edici olarak snflandrlmtr. PH 7.0’da% 16 kat olan baka bir sodyum lauriminodipropionat çözeltisi orta derecede tahri ediciydi.% 0.1 sodyum lauriminodipropionat ile intrakütan olarak enjekte edilen kobaylarda hiçbir duyarllk gözlemlenmedi. Sodyum Lauriminodipropionate’in Güvenlik Deerlendirmesi. SODIUM LAURIMINODIPROPIONATE Sodyum lauriminodipropionate’in cilt için “pratik olarak toksik olmad” ve cilt temas üzerine “minimum düzeyde tahri edici” olduu bildirilmitir. Ayrca gözü “minimal düzeyde tahri ettii” bildirildi. Sodyum lauriminodipropionat, yutulduunda “pratik olarak toksik deildi”.sodyum Lauriminodipropionate Güvenlik Deerlendirmesine likin Nihai Rapordan. 104 denek kullanlarak% 2,2 sodyum lauriminodipropionatn (% 30 çözeltinin% 7,34’ü) temas duyarlln indükleme potansiyeline sahip insan tekrarl bir yama testi (HRIPT) gerçekletirildi. ,% 3,5 aktif sodyum lauriminodipropionatn (% 30 solüsyonun% 11,67’si) temas duyarlln indükleme potansiyeli 116 denekte incelenmitir.2 Mevcut FDA VCRP verileri, sodyum lauriminodipropionatn 10 kozmetik formülasyonda, özellikle saç kremlerinde kullanldn göstermektedir. Saç kremlerinde sodyum lauriminodipropionatn mevcut kullanm konsantrasyonu% 0.05’tir. Disodyum lauriminodipropionatn 2 yüz ve boyun preparatnda kullanld bildirilmitir. Lauriminodipropionic acid için herhangi bir kullanm rapor edilmemitir. Disodyum tuzu veya asit için herhangi bir kullanm konsantrasyonu bildirilmemitir. Sodyum lauriminodipropionat, ar hizmet alkali temizleyiciler, korozyon inhibitörleri, deri temizleyiciler ve asit temizleyicilerde uygulamalara sahiptir. Çevre Koruma Ajans (EPA), N-alkil (C8-C18) -beta-iminodipropionik asidin sodyum ve potasyum tuzlarnn, pestisit formülasyonlarnda ön ve Gda mahsullerinde hasat sonras uygulamalar: Yap aktivitesi ilikisi (SAR) deerlendirmesinin özelliklerine dayanan olas bir metabolik ema, sodyum lauriminodipropionatn muhtemelen glukuronidasyon ve / veya N-dealkilasyon ile metabolize edilebileceini ileri sürdü. % 10 aktif sodyum lauriminodipropionat çözeltileri üzerinde yaplan çalmalarda, sçanlar için oral LD50 31.3 g / kg ve dermal LD50 10.2 g / kg’dan büyüktü; % 16 kat çözelti içeren fareler için oral LD50 17,8 ml / kg olarak tahmin edilmitir.% 10,5 sodyum lauriminodipropiyonat (% 30 çözeltinin% 35’i) damtlm suda% 20 w / w çözelti alan tavanlarda 91 günlük bir çalma sodyum lauriminodipropionatn dermal veya sistemik toksisiteye neden olmad ancak dermal bir tahri edici olduu sonucuna varmtr. 13 hafta boyunca% 1.5 disodyum lauriminodipropionat içeren bir saç boyas formülasyonunun topikal uygulamalarn alan tavanlarda hiçbir sistemik etki gözlenmemitir. Potansiyel sodyum lauriminodipropionat metabolitleri için yaplan bir yap aktivitesi deerlendirmesi, metabolitlerin geliimsel veya üreme için toksik olmad sonucuna varmtr. Sçanlarda% 1.5 disodyum lauriminodipropionat içeren bir saç boyas formülasyonu üzerinde yaplan bir gelitirme çalmas, embriyotoksik veya teratojenik etkiler gözlemlememitir. Sodyum lauriminodipropionat, bir Ames testinde mutajenik deildi ve bir CHO hücre analizinde klastojenik deildi.% 10 aktif çözeltide sodyum lauriminodipropionat, tavanlarn derisini ciddi ekilde tahri ediyordu. % 16 kat orannda sodyum lauriminodipropionat tavan derisi için orta derecede tahri ediciydi. Sodyum lauriminodipropionat tavanlarn gözlerini tahri ediciydi. % 3.56 aktif sodyum lauriminiodipropionat içeren iki ampuan formülasyonu, insanlarda gözyalarnda oküler lezyonlara neden olmad veya albümin seviyelerinde önemli bir arta neden olmad. Çalmann her iki aamasnda da minimum batma veya kuruluk hissi gözlemleri yaplmtr.Kobaylarla yaplan çalmalarda sodyum lauriminodipropionata duyarllk kant yoktu. % 2,2 aktif sodyum lauriminodipropionat ve% 3,5 aktif sodyum lauriminodipropionat içeren bir ampuan formülasyonu içeren köpüklü bir yüz ykama, HRIPT çalmalarnda gecikmi temas ar duyarllna neden olmad. 1997 ylnda sodyum lauriminodipropionat ve sodyum lauraminopropionat için bir güvenlik deerlendirmesi yaynland ve mevcut olduu sonucuna varld. kozmetikte güvenliklerini desteklemek için veriler yetersizdi. Uzman Heyeti, yeni verilere dayanarak sodyum lauriminodipropiyonat ile ilgili nihai raporu yeniden açt ve raporun ayn zamanda lauriminopropionik asit ve disodyum lauriminodipropionatn güvenliini de ele almas gerektiini belirledi. Panel, sodyum lauraminopropionat için yetersiz veri olduu sonucunu yeniden teyit etti. CIR Uzman Paneli, Üreme ve geliimsel toksisite çalmalar da dahil olmak üzere mevcut tek doz ve tekrarlanan doz hayvan çalmalar, sodyum lauriminodipropiyonatn güvenliini destekledi.Uzman Paneli, karsinojenisite verilerinin olmadn kaydetti, ancak sodyum lauriminodipropionatn, in vitro genotoksisite çalmalar, bu bileenlerin güvenliini desteklemek için yeterliydi. Kozmetik çerik nceleme Uzman Paneli, kozmetikte kullanlan lauriminodipropionic asit, sodyum lauriminodipropionate ve disodyum lauriminodipropionate’in güvenliini deerlendirdi. Bu bileenler, kozmetikte saç bakm maddeleri ve yüzey aktif madde temizleme maddeleri olarak ilev görür. Panel, kozmetikte bu bileenlerin güvenlii ile ilgili hayvan ve insan verilerini inceledi. Panel, lauriminodipropionic asit, sodyum lauriminodipropionate ve disodyum lauriminodipropionate’in mevcut kullanm ve konsantrasyon uygulamalarnda kozmetik bileenler olarak güvenli olduu sonucuna varmtr. . Bu bileenler, kozmetikte saç bakm maddeleri ve yüzey aktif madde temizleme maddeleri olarak ilev görür. Panel, kozmetikte bu bileenlerin güvenlii ile ilgili hayvan ve insan verilerini inceledi. Panel, lauriminodipropionic asit, sodyum lauriminodipropionate ve disodyum lauriminodipropionate’in mevcut kullanm ve konsantrasyon uygulamalarnda kozmetik bileenler olarak güvenli olduu sonucuna varmtr. ve kozmetik formülasyonlarda antistatik bir ajan. 1997’de Cosmetic Ingredient Review (CIR) tarafndan yaynlanan sodyum lauriminodipropionate ve sodyum lauraminopropionate için bir güvenlik deerlendirmesinde ,1 CIR Uzman Paneli mevcut verilerin kozmetikte kullanm için her iki bileenin güvenliini desteklemek için yetersiz olduu sonucuna varmtr. kozmetikte kullanlan sodyum lauriminodipropionatn güvenliini destekleyen ürünler mevcuttur.Sodyum lauriminodipropionata kimyasal benzerliklerinden dolay, CIRExpert Paneli yeni mevcut verilerin ana bileie, lauriminodipropionikasite ve disodyum tuzuna ekstrapole edilebileceini belirledi. Sodyum lauraminopropionat için yeni güvenlik testi verisi mevcut deildi; bu nedenle, CIR Uzman Paneli, nihai raporu bu bileeni içerecek ekilde yeniden açmad ve sodyum lauraminopropionat için yetersiz veri olduu sonucunu yeniden dorulad.Deriphat 160C, inorganik tuzlarn çözünürlüünü artran mükemmel ya giderme yetenekleri ile sert yüzey temizleyicileri ve I&I uygulamalar için çok ilevli bir yüzey aktif cismidir. ve kokular ve katyonik koruyucular gibi organik katk maddeleri. Deriphat 160 ayrca korozyon önleme salar ve oldukça asidik ve oldukça alkali koullar altnda stabildir. Sert yüzeylere olan yaknl uzun süreli etkilere izin verir. Deriphat 160 C, özellikle mutfak ya çözücüleri, banyo temizleyicileri ve kurumsal temizleyiciler dahil olmak üzere metalle temas için dezenfektan temizleyiciler ve temizleyiciler için tavsiye edilir.Kadmiyum zehirli ve zararl bir ar metal olarak 19. Yüzyln balarnda sanayileme ve youn tarma geçi ile etrafa yaylarak ciddi bir çevre kirleticisi haline gelmitir. Kadmiyumunnitel ve nicel tayini için birçok kimyasal ve enstrümantal yöntemler olmasna ramen, çou zaman bu yöntemlerde çok zehirli potasyum siyanür içeren ortamda kadmiyumun-dithizone kompleksinin olumas ve bu kompleksin kloroform ve karbon tetraklorür gibi kanserojen klorlu organik çözücü içine alnmalar gerekmektedir. Bu çalmann temel amac kadmiyumu dithizone kullanarak tayin etmek için hassas, basit, hzl güvenli ve daha az zehirli ve zararl kimyasallar maddelerin kullanld bir spektroskopi-kimyasal yöntem gelitirmekti. Burada rapor edilen sonuçlar ümit verici olup, Deriphat-160 isimli yüzey aktif madde içeren bazik sulu bir ortamda kadmiyum-dithizonekompleksinin çökmeden oluturulabildiini ve incelenen Cdmikromolarderiim aralnda kompleksin Beer’syasasna uyduunu göstermektedir. Spektroskopik ölçümü için hazrlanan çözeltilerde ne siyanür kullanlmasna gerek olmu ne de oluan kompleksi klorlanm organik çözücüler için alnmalar gerekmemitir. Anahtar kelimeler: dithizone, kadmiyum, yüzeyaktif, spektrofotometrik, Deriphat-160C.