PVP/VA W-635
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate)
CAS No. : 25086-89-9
EC No. : 607-540-1
Synonyms:
Vinylpyrrolidone; vinylacetate copolymer; vinyls; polyvinylpyrrolidone and vinylpyrrolidone copolymers (PVP); Polyvinylpyrrolidone/vinyl acetate; Polivinilpirolidon Vinil Asetat; vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; PVP/VA W 735; PVP-VA W 735; PVP VA W 735; PVP/VA W-635; PVP/VA W/735;PVP-VA E-335; PVP-VA E-335; PVP-VA E-735; PVP-VA E-735; PVP-VA I-335; PVP/VA 37 E; PVP/VA 37 I; PVP/VA 55 E; PVP/VA 55 I; PVP/VA 64 E; PVP/VA E 335; PVP/VA E 535; PVP/VA E 735; PVP/VA E 735; PVP/VA I-735; PVP/VA E-735; PVP/VA E-735; PVP/VA I-735; PVP/VA W-635; PVP/VA E-735; PVP/VA E-535; PVP/VA I-535; PVP/VA I-335; PVP/VA I-735;Luviskol VA 37 E ; Luviskol VA 37 I ; Luviskol VA 55 I ; Luviskol VA 64 P ; Luviskol VA 64 W ; Luviskol VA 73 W ; Luviskol VA 73 E; Luviskol VA 37 E 2; Luviskol VA 37 I ; Luviskol VA 55 I ; Luviskol VA 64 P ; Luviskol VA 64 W ; Luviskol VA 73 W ; Luviskol VA 73 E ethenyl acetate;1-ethenylpyrrolidin-2-one; copovidone; Kollidon VA64; poly(V-co-V-Ac); poly(vinyl pyrrolidone-co-vinyl acetate); poli(vinil pirolidon-ko-vinil asetat); poly(vinylpyrrolidone-co-vinyl-acetate); poli(vinilpirolidon-ko-vinil-asetat); PVP VA64; PVP-VA; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Luviskol VA 281; Gantron S 860; Luviskol VA 28 I; Luviskol VA 37 E; PVP-VA; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-vinylpyrrolidone polymer; vinil asetat-vinilpirolidon polimer; Vinylpyrrolidone-vinyl acetate polymer; vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; 1-vinil pirolidon vinil asetat; acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; ethenyl acetate;1-ethenylpyrrolidin-2-one; poly(1-vinyl pyrrolidone-co-vinyl acetate); VP/VA COPOLYMER, 1-ETHENYL-2-PYRROLIDINONE, POLYMER WITH ACETIC ACID ETHENYL ESTER; 1-ETHENYL-2-PYRROLIDINONE, POLYMER WITH ETHENYL ACETATE; ACETIC ACID ETHENYL ESTER, POLYMER WITH 1ETHENYL2PYRROLIDINONE; ACETIC ACID, ETHENYL ESTER, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE; ETHENYL ACETATE, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE; ETHENYL ESTER POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE ACETIC ACID; POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE ACETIC ACID, ETHENYL ESTER; POLYMER WITH ACETIC ACID ETHENYL ESTER 1-ETHENYL-2-PYRROLIDINONE; POLYMER WITH ETHENYL ACETATE 1-ETHENYL-2-PYRROLIDINONE; PVP/ VA COPOLYMER; PVP/VA COPOLYMER; 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Gantron S 860; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); PVP-VA; Ganex E 535; GAF-S 630; Vinyl acetate-vinylpyrrolidone polymer; Vinylpyrrolidone-vinyl acetate polymer; Luviskol VA 281; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; Luviskol VA 28 I; Luviskol VA 37 E; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; poli(vinil pirolidon-ko-vinil asetat); poly(vinylpyrrolidone-co-vinyl-acetate); poli(vinilpirolidon-ko-vinil-asetat); PVP VA64; PVP-VA; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Luviskol VA 281; Gantron S 860; Luviskol VA 28 I; Luviskol VA 37 E; PVP-VA; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-vinylpyrrolidone polymer; vinil asetat-vinilpirolidon polimer; Vinylpyrrolidone-vinyl acetate polymer ;vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer ;Vinyl acetate-N-vinylpyrrolidinone polymer ;Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; 1-ethenylpyrrolidin-2-one; copovidone; Kollidon VA64; poly(V-co-V-Ac); poly(vinyl pyrrolidone-co-vinyl acetate); poli(vinil pirolidon-ko-vinil asetat); poly(vinylpyrrolidone-co-vinyl-acetate); poli(vinilpirolidon-ko-vinil-asetat); PVP VA64; PVP-VA; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Vinylpyrrolidone; vinylacetate copolymer; vinyls; polyvinylpyrrolidone and vinylpyrrolidone copolymers (PVP); Polyvinylpyrrolidone/vinyl acetate; Polivinilpirolidon Vinil Asetat; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-vinylpyrrolidone polymer; vinil asetat-vinilpirolidon polimer; Vinylpyrrolidone-vinyl acetate polymer; vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; 1-vinil pirolidon vinil asetat; acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; ethenyl acetate;1-ethenylpyrrolidin-2-one; poly(1-vinyl pyrrolidone-co-vinyl acetate); Ganex E 535; GAF-S 630; Vinyl acetate-vinylpyrrolidone polymer; Vinylpyrrolidone-vinyl acetate polymer; Luviskol VA 281; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; Luviskol VA 28 I; Luviskol VA 37 E; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-N-vinylpyrrolidinone copolymer; E 535; I 535; I 735; I 735; S 630; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; MFCD00134018; 2-Pyrrolidinone, polymer with ethenyl acetate; AC1L6PLN; AC1Q5XA0; SCHEMBL29127; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone ; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; 1-vinil pirolidon vinil asetat; PVP VA W 735; PVP_VA W 735; PVP VA W735; PVP/VAW-735; PVPVAW735; PVP WA W 735; pvp wa w 735; pvp- wa -w- 735; pvp /wa /w /735; pvp -wa- w 735; PVP/VA Copolymer
PVP/VA W-635
VP/VA Copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a film former. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) copolymer in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.
Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions.
What is PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer?
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel’s, wax’s, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum.
PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties.
This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around.
Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations.
Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal.
The advantages of using PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers as film formers are:
• film flexibility
• good adhesion
• water remoistenability
• hardness
These properties make PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates.
• Linear, random copolymers
• Increasing vinyl acetate content – increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg
• Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals
• Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50%
• Adhesive and cohesive properties
• E = ethanol (EtOH), I = isopropanol, W = water, S = solid
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E and I copolymer Series
To fit many application areas, the E and I series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties – water sensitivity, viscosity, softening point, etc.
This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S copolymer
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate)
W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution.
VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer.
Plasticizers and Polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing.
Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735 copolymer, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 copolymer and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- 335 copolymer. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymer is less hygroscopic than PVP.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are widely used for their excellent film forming properties in the following applications and markets:
In hot melt adhesives, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are used in a variety of water remoistenable or water removable adhesives as listed
below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists.
Storage and handling
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in
the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.
Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- and I-series
To fit more application areas, the E- and I-series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties – water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair.
Plasticizers and polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing.
Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-335. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is less hygroscopic than PVP.
Abstract
In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach).
The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios.
Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods.
As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain.
Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability.
PVP/VA Copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA).
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1]
What is PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer?
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel’s, wax’s, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties.
This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below)
Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E and I copolymer Series
To fit many application areas, the E and I series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties – water sensitivity, viscosity, softening point, etc.
This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios.
Storage and handling
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.
Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- and I-series
To fit more application areas, the E- and I-series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties – water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA.
The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 70/30 copolymer of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair.
Plasticizers and polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing.
Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-335. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is less hygroscopic than PVP.
Uses
Medical
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.)
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens.
Technical
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an adhesive in glue stick and hot-melt adhesives
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an emulsifier and disintegrant for solution polymerization
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in aqueous metal quenching
for production of membranes, such as dialysis and water purification filters
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a thickening agent in tooth whitening gels[10]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an additive to Doro’s RNA extraction buffer[citation needed]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a stabilizing agent in all inorganic solar cells[13]
Other uses
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.
As a food additive, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers.
In molecular biology, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) can be used as a blocking agent during Southern blot analysis as a component of Denhardt’s buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR.
In microscopy, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is useful for making an aqueous mounting medium.[16]
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17]
Safety of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate)
The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21]
Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) instead.[22][23]
Properties of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate)
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings.
A 2014 study found fluorescent properties of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) and its oxidized hydrolyzate.
History of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate)
PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production.
PVP/VA W-635
VP / VA Kopolimer. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) bir film oluturucudur. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), 70/30 (VP / VA) orannda monomerlerin serbest radikal polimerizasyonu ile üretilir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), güçlü ve sert tutu, gelimi yüksek nem kvrlma tutuu ve iyi itici uyumluluu sunar. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), saç spreyleri, renklendiriciler, köpükler, jeller, ekillendirici losyonlar / kremler ve yeni ekillendiriciler gibi alkolsüz ve saç bakm ürünlerinin formüle edilmesinde uygulama bulur. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), suda% 50 dorusal ve rastgele polivinilpirolidon / vinil asetat (PVP/VA W-635 (Polivinilpirolidon Vinil Asetat)) kopolimer çözeltisidir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) cama, plastie ve metale yapan effaf, esnek ve oksijen geçirgen filmler oluturur.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), 70/30 VP / VA orannda monomerler üzerinde serbest radikal polimerizasyonu ile üretilen bir film oluturucudur. Suda% 50 lineer ve rastgele polivinilpirolidon / vinil asetat (PVP / VA) kopolimer çözeltisidir. PVP / VA W-Serisi kopolimerler, 30/70 ila 40/60 vinil asetat (VA) ile vinilpirolidon (VP) arasnda deien monomerlerin suda salanan serbest radikal polimerizasyonu ile üretilen dorusal, rastgele kopolimerlerdir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.
Polivinilpirolidon / vinil asetat (PVP/VA W-635 (Polivinilpirolidon Vinil Asetat)) reçineler, 70/30 ila 30/70 vinil asetattan vinilpirolidona deien oranlarda monomerlerin serbest radikal polimerizasyonu ile üretilen dorusal, rastgele kopolimerlerdir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, beyaz tozlar veya etanol, izopropanol ve su içinde berrak çözeltiler halinde mevcuttur. Vinilpirolidon içeriinin dört aralndaki polimerler (yüzde 30, 50, 60 ve 70) etanol veya izopropanolde üretilir. Yüzde 60 ve 70 vinilpirolidon içerikli PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri kat veya yüzde 50 sulu çözelti olarak mevcuttur.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Kopolimer nedir?
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Kopolimer, tutunma faktörünü salayan çou ana saç bakm ürününde bulunan bileendir. Bu nedenle, çou Saç spreyinde çok yaygndr, ancak ayn zamanda jellerde, ada, pomatlarda ve ekillendirici kremlerde de bulunur. Petrolden elde edilen sentetik bir bileendir.
PVP (Polivinilpirolidon olarak da bilinir), 1950’lerin banda gerçekten baarl ilk saç spreylerinin ana maddesiydi. Bu polimer, suda çözünür olduu için saç spreyi olarak çalt. Bu, saçnz ykarken durulanabilecei anlamna geliyordu. PVP, havadaki suyu emme eilimindeydi ve saça altmlarda çok yaygn olan o yapkan görünümü verdi.
Bu, polidimetilsiloksan ad verilen bir silikon olan baka bir polimerin yardmyla sabitlendi. Bu silikonun nasl daha iyi bir saç spreyi yaptn anlamak, ilk etapta saç spreyinin nasl çaltn anlamaya yardmc olur. Üzerine püskürttüünüzde, polivinilpirolidon saç üzerinde ince bir tabaka oluturur. Bu kaplama serttir ve saçn hareket etmesini engeller.
Ne yazk ki hiç kimse bu Polimer ile gelen tehlikelerin farknda deildi. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Kopolimer partikülleri solunursa hassas kiilerde akcierlere zarar verebilir. nsanlarn akcierlerindeki yabanc cisimlere partiküller katkda bulunabileceinden toksik olarak kabul edilebilir. Birkaç yl öncesine kadar, bu bileenin kullanmnn güvenli olduu düünülüyordu, ancak imdi kesinlikle kaçnlmas daha iyi bir bileendir.
Burada, bu bileeni HÇBR ürünümüzde ve özellikle de Saç Spreyimizde kullanmyoruz. Greyfurt ve Limon Otu Saç Spreyimiz size sadece nazik olmakla kalmaz, ayn zamanda aerosol içermeyen ve bunun yerine çevre dostu bir tetikleyici sprey bulundurarak çevreye kar da naziktir. Bu güzel ürün, doal bir UV koruyucu ve tutma faktörü içerir, bu da petro-kimyasallar, plastikler veya polimerler olmad anlamna gelir. Bu nazik formül ayn zamanda artk göz ve kafa derisi tahrii olmad anlamna da gelir.
Ashland, formülatörlere bir dizi vinilpirolidon / vinil asetat kopolimeri sunmaktadr. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimer serisinin üyeleri, farkl derecelerde su direnci gerektiren çeitli ürünlerde birincil film oluturucular olarak hizmet eder. Bu kopolimerler saç, cilt ve ahap, cam, kat ve metal gibi pürüzsüz yüzeyler için özel afinite sergiler, ancak çkarlmas için çözücülere ihtiyaç duymazlar.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerlerini film oluturucu olarak kullanmann avantajlar unlardr:
• film esneklii
• iyi yapma
• suyun yeniden nemlendirilebilirlii
• sertlik
Bu özellikler, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerlerini çeitli endüstriyel, kiisel bakm ve farmasötik ürünler için uygun hale getirir. Balca endüstriyel uygulamalar, scakta eriyen yaptrclar, fotoresist balayclar ve mürekkep püskürtmeli ortam kad, plastik film ve dier substratlar için kaplamalardr.
• Dorusal, rastgele kopolimerler
• Vinil asetat içeriini artrmak – hidrofobiklii arttrmak, higroskopiklii azaltmak, Tg’yi azaltmak
• Cam, plastik ve metallere yapan hidrofilik, effaf, esnek termoplastik, oksijen geçirgen filmler
• Alkoller, esterler ve ketonlarda çözünür, eterler ve alifatik hidrokarbonlarda çözünmez. VP içerii% 50’den fazla olduunda suda çözünür
• Yapkan ve kohezif özellikler
• E = etanol (EtOH), I = izopropanol, W = su, S = kat
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E ve I kopolimer Serisi
Pek çok uygulama alanna uymas için, E ve I serisi PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, srasyla etanol ve izopropanol2 içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E- 335, E-535, E-635, E-735 ve I grubunda üç tane: 1-335, 1-535, 1-735. Her biri monomer orannda ve dolaysyla özelliklerde farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas vb.
Bu, formülatörlere belirli uygulamalar için yeni ürünler yaratmada önemli ölçüde esneklik salar. Tüm bu kopolimerlerin oluturduu effaf filmler, yapma, parlaklk, sertlik ve yeniden slanabilirlik ile karakterize edilir. Pek çok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek oranl ürünlere göre daha fazla nem direnci sergilemektedir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) S kopolimeri
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Beyaz, kokusuz bir toz olan S-630 kopolimer, 60/40 VP / VA arlk orannda da mevcuttur. Minimum kritik çözelti scakl yaklak 70 ° C olan, yüksek moleküler arlkl, çözücü ve suda çözünür bir kopolimerdir. Çözeltilerden dökülen filmler parlak, yar saydam ve suyla yeniden slanabilir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W kopolimerleri
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W-735 kopolimer, suda% 50 çözelti olarak salanan 70/30 PVP ve vinil asetat kopolimeridir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat)
W-635 kopolimer,% 50 sulu çözelti olarak da salanan 60/40 kopolimerdir.
VA (vinil asetat), VP’den (vinilpirolidon) daha hidrofobik bir moleküldür. Bu nedenle, kopolimerin artan VA içerii, hidrofobiklikte bir arta ve dolaysyla VP homopolimerine göre suda çözünürlük ve higroskopide bir azalmaya neden olur.
Plastikletiriciler ve Polimerler: Çou PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri çeitli noniyonik ve katyonik polimerlerle uyumludur. Anyonik kopolimerler ile uyumluluk, kartrmadan önce nötrletirme yoluyla salanabilir.
Filmlerin higroskopiklii: PVP / VA kopolimer filmlerin doal su hassasiyeti monomer oranna göre deiir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-735 kopolimer, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-535 kopolimer ve PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E için tipik veriler aada gösterilmitir. – 335 kopolimer. Genel olarak, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimeri, PVP’den daha az higroskopiktir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, aadaki uygulamalarda ve pazarlarda mükemmel film oluturma özellikleri için yaygn olarak kullanlmaktadr:
Scakta eriyen yaptrclarda, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, listelenen çeitli suyla yeniden nemlendirilebilir veya suyla çkarlabilir yaptrclarda kullanlr.
altnda. Burada formülatörlere film esneklii, yapkanlk ve suyun yeniden nemlendirilebilirliinde performans avantajlar sunarlar.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, boya emiciliini artrmak için kat, plastik filmler ve dier substratlar dahil olmak üzere mürekkep püskürtmeli ortam için kaplamalarda da kullanlr. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) S-630 kopolimeri, fotorezistlerin sulu olarak ilenmesine izin vermek için balayc olarak kullanlr.
Saklama ve kullanma
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, normal saklama koullar altnda en az bir yl boyunca stabildir, ancak nem birikmesini önlemek için sk önlemler alnmaldr. E ve I serilerinin parlama noktalar var
50-55 ° F (10-13 ° C) aralndadr ve yanc (DOT Yanc) malzemeler olarak snflandrlr. Güvenlik nedenleriyle ve scaklk deiiklikleriyle birlikte tambur solumasna bal nem birikmesini önlemek için, 100 ° F (38 ° C) altnda kuru bir yerde saklayn ve patlamaya dayankl tesislerde yeniden paketleyin veya kullann.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.
Polivinilpirolidon / vinil asetat (PVP/VA W-635 (Polivinilpirolidon Vinil Asetat)) reçineler, 70/30 ila 30/70 vinil asetattan vinilpirolidona deien oranlarda monomerlerin serbest radikal polimerizasyonu ile üretilen dorusal, rastgele kopolimerlerdir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, beyaz tozlar veya etanol, izopropanol ve su içinde berrak çözeltiler halinde mevcuttur. Vinilpirolidon içeriinin dört aralndaki polimerler (yüzde 30, 50, 60 ve 70) etanol veya izopropanolde üretilir. Yüzde 60 ve 70 vinilpirolidon içerikli PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri kat veya yüzde 50 sulu çözelti olarak mevcuttur.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E- ve I-serisi
Daha fazla uygulama alanna uymas için, E- ve I-serisi PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri srasyla etanol ve izopropanol ** içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E-335, E-535, E-635, E-735 ve I grubunda üç tane: I-335, I-535, I-735. Her biri monomer oran ve dolaysyla özellikleri bakmndan farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas, vb. Bu, formülatörlere özel uygulamalar için yeni ürünler yaratmada önemli bir esneklik salar. Tüm bu kopolimerlerin oluturduu effaf filmler, yapma, parlaklk, sertlik ve yeniden slanabilirlik ile karakterize edilir. Pek çok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek VP / VA oranlarna sahip ürünlere göre daha fazla nem direnci sergiler.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W kopolimerleri
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W-735, suda% 50 çözelti olarak salanan 70/30 PVP ve vinil asetat kopolimeridir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W-635, ayrca% 50 sulu çözelti olarak salanan 60/40 kopolimerdir. Alkolsüz köpükler ve jeller için ideal noniyonik fiksatif reçinelerdir. Formül yapclara saçta birikme, dökülme veya matlama olmadan olaanüstü kvrlma ve stil tutma özellikleri sunarlar.
Plastikletiriciler ve polimerler: Çou PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri çeitli noniyonik ve katyonik polimerlerle uyumludur. Anyonik kopolimerler ile uyumluluk, kartrmadan önce nötrletirme yoluyla salanabilir.
Filmlerin higroskopiklii: PVP / VA kopolimer filmlerin doal su hassasiyeti monomer oranna göre deiir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-735, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-535 ve PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-335 için tipik veriler aada gösterilmitir . Genel olarak, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), PVP’den daha az higroskopiktir.
Öz
Bu çalmada, kopolimer bileiminin ilaç-polimer çözünürlüüne etkisi aratrlmtr. Model ilaç selekoksibin (CCX) çeitli polivinilpirolidon / vinil asetat (PVP/VA W-635 (Polivinilpirolidon Vinil Asetat)) kopolimer bileimlerinde (70/30, 60/40, 50/50 ve 30/70 w / w) çözünürlüü ) ve saf homopolimerler polivinilpirolidon (PVP) ve polivinil asetat (PVA), ar doymu bir amorf dispersiyonun yeniden kristalletirilmesine dayanan bir termal analiz yöntemi (yeniden kristalletirme yöntemi) kullanlarak 25 ° C’de tahmin edildi. Bu çözünürlükler, Flory-Huggins kafesi kullanlarak, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), N-vinilpirolidon (NVP) ve vinil asetat (VA) sv monomerik öncülerindeki CCX çözünürlüüne dayal bir tahminle karlatrld. teorisi (sv monomer çözünürlük yaklam).
Sv monomer çözünürlük yaklamndan tahmin edilen çözünürlükler, VP / VA orannn 0.03-0.60 w / w’den artmasyla dorusal olarak artt. Yeniden kristalletirme yönteminden tahmin edilen çözünürlükler, 0.02-0.40 w / w’den artan VP / VA oran ile artm olsa da, tahmin edilen çözünürlük yüksek VP / VA oranlarnda bir platoya yaklayor gibi göründü.
Gordon-Taylor denkleminden artan VP / VA oran ile artan pozitif sapmalar, her iki yöntem kullanlarak tahmin edilen nispeten yüksek çözünürlüklere uygun olarak, CCX ve VP tekrar birimi arasnda güçlü etkileimlere iaret etti.
Çözünürlük platosu, CCX ve VP tekrar birimleri arasndaki boyut farkllklarnn neden olduu sterik engelin bir sonucu olabileceinden, bir VP tekrar birimi ile etkileime giren bir CCX molekülünün, baka bir CCX molekülünün içindeki komu tekrar birimlerine balanmasn engellemesi olasdr. polimer zinciri.
Bu nedenle, bu komu higroskopik VP tekrar birimlerinin hidrofobik VA tekrar birimleriyle deitirilmesinin, ilaç-polimer çözünürlüünden ödün vermeden amorf bir kat dispersiyonun fiziksel stabilitesini arttrmas mümkündür. Kopolimerler, optimal ilaç-polimer çözünürlüü ve fiziksel stabilite salayacak ekilde özelletirilebildiinden, bu bilgi amorf ilaç verme sistemlerinin gelecekteki gelitirilmesinde avantajl bir ekilde kullanlabilir.
PVP / VA Kopolimer. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) bir film oluturucu madde olarak ilev görür. Cam, plastik ve metale yapan effaf, esnek ve oksijen geçirgen filmler oluturur. Güçlü ve sert tutu, gelimi yüksek nem kvrlma tutuu ve iyi itici uyumluluu sunar. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), saç spreyleri, renklendiriciler, köpükler, jeller, ekillendirici losyonlar / kremler ve yeni ekillendiriciler gibi alkolsüz ve saç bakm ürünlerinin formüle edilmesinde uygulama bulur. Suda% 50 lineer ve rastgele polivinilpirolidon / vinil asetat (PVP / VA) kopolimer çözeltisidir. Monomerlerin 60/40 (VP / VA) orannda serbest radikal polimerizasyonu ile üretilir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) termoplastik, dorusal, rastgele vinilpirolidon / vinilasetat kopolimeri. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) endüstriyel, özel ve görüntülü kaplamalar, bask mürekkepleri ve boyalarda kullanlr. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) cam, plastik ve metallere effaflk, esneklik, oksijen geçirgenlii ve yapma salar.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) endüstriyel olarak 2-pirolidonun vinillenmesi, yani asetilen ile baz katalizli reaksiyon ile üretilir. [2] PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), önemli bir sentetik malzeme olan polivinilpirrolidonun (PVP) öncüsüdür. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) monomeri, mürekkep, kaplama veya yaptrc olarak uygulanan ultraviyole ve elektron nyla kürlenebilen polimerlerde reaktif bir seyreltici olarak yaygn olarak kullanlmaktadr. [2] Yaygn olarak polividon veya povidon olarak da adlandrlan polivinilpirolidon (PVP), N-vinilpirolidon monomerinden yaplan suda çözünür bir polimerdir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Kopolimer nedir?
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Kopolimer, tutunma faktörünü salayan çou ana saç bakm ürününde bulunan bileendir. Bu nedenle, çou Saç spreyinde çok yaygndr, ancak ayn zamanda jellerde, ada, pomatlarda ve ekillendirici kremlerde de bulunur. Petrolden elde edilen sentetik bir bileendir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) (Polivinilpirolidon olarak da bilinir) 1950’lerin balarnda gerçekten baarl ilk saç spreylerinin ana maddesiydi. Bu polimer, suda çözünür olduu için saç spreyi olarak çalt. Bu, saçnz ykarken durulanabilecei anlamna geliyordu. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) havadaki suyu emme eilimindeydi ve saça altmlarda çok yaygn olan yapkan bir görünüm kazandrd.
Bu, polidimetilsiloksan ad verilen bir silikon olan baka bir polimerin yardmyla sabitlendi. Bu silikonun nasl daha iyi bir saç spreyi yaptn anlamak, ilk etapta saç spreyinin nasl çaltn anlamaya yardmc olur. Üzerine püskürttüünüzde, polivinilpirolidon saç üzerinde ince bir tabaka oluturur. Bu kaplama serttir ve saçn hareket etmesini engeller. (Aadaki resme bakn)
Ne yazk ki hiç kimse bu Polimer ile gelen tehlikelerin farknda deildi. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) Kopolimer partikülleri solunursa hassas kiilerde akcierlere zarar verebilir. nsanlarn akcierlerindeki yabanc cisimlere partiküller katkda bulunabileceinden toksik olarak kabul edilebilir. Birkaç yl öncesine kadar, bu bileenin kullanmnn güvenli olduu düünülüyordu, ancak imdi kesinlikle kaçnlmas daha iyi bir bileendir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E ve I kopolimer Serisi
Pek çok uygulama alanna uymas için, E ve I serisi PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, srasyla etanol ve izopropanol2 içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E- 335, E-535, E-735, E-735 ve I grubunda üç tane: 1-335, 1-535, 1-735. Her biri monomer orannda ve dolaysyla özelliklerde farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas vb.
Bu, formülatörlere belirli uygulamalar için yeni ürünler yaratmada önemli ölçüde esneklik salar. Tüm bu kopolimerlerin oluturduu effaf filmler, yapma, parlaklk, sertlik ve yeniden slanabilirlik ile karakterize edilir. Pek çok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek oranl ürünlere göre daha fazla nem direnci sergilemektedir.
Saklama ve kullanma
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, normal saklama koullar altnda en az bir yl boyunca stabildir, ancak nem birikmesini önlemek için sk önlemler alnmaldr. E ve I serileri 50-55 ° F (10-13 ° C) aralnda parlama noktalarna sahiptir ve yanc (DOT Yanc) malzemeler olarak snflandrlr. Güvenlik nedenleriyle ve scaklk deiiklikleriyle birlikte tambur solumasna bal nem birikmesini önlemek için, 100 ° F (38 ° C) altnda kuru bir yerde saklayn ve patlamaya dayankl tesislerde yeniden paketleyin veya kullann.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.
Polivinilpirolidon / vinil asetat (PVP/VA W-635 (Polivinilpirolidon Vinil Asetat)) reçineler, 70/30 ila 30/70 vinil asetattan vinilpirolidona deien oranlarda monomerlerin serbest radikal polimerizasyonu ile üretilen dorusal, rastgele kopolimerlerdir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri, beyaz tozlar veya etanol, izopropanol ve su içinde berrak çözeltiler halinde mevcuttur. Vinilpirolidon içeriinin dört aralndaki polimerler (yüzde 30, 50, 60 ve 70) etanol veya izopropanolde üretilir. Yüzde 60 ve 70 vinilpirolidon içerikli PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri kat veya yüzde 50 sulu çözelti olarak mevcuttur.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E- ve I-serisi
Daha fazla uygulama alanna uymas için, E- ve I-serisi PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri srasyla etanol ve izopropanol ** içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E-335, E-535, E-735, E-735 ve I grubunda üç tane: I-335, I-535, I-735. Her biri monomer oran ve dolaysyla özellikleri bakmndan farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas, vb. Bu, formülatörlere özel uygulamalar için yeni ürünler yaratmada önemli bir esneklik salar. Tüm bu kopolimerlerin oluturduu effaf filmler, yapma, parlaklk, sertlik ve yeniden slanabilirlik ile karakterize edilir. Pek çok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek VP / VA oranlarna sahip ürünlere göre daha fazla nem direnci sergiler.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W kopolimerleri
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W-735, suda% 50 çözelti olarak salanan PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) ve vinil asetatn 70/30 kopolimeridir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) W-735,% 50 sulu çözelti olarak da salanan 60/40 kopolimerdir. Alkolsüz köpükler ve jeller için ideal noniyonik fiksatif reçinelerdir. Formül yapclara saçta birikme, dökülme veya matlama olmadan olaanüstü kvrlma ve stil tutma özellikleri sunarlar.
Plastikletiriciler ve polimerler: Çou PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) kopolimerleri çeitli noniyonik ve katyonik polimerlerle uyumludur. Anyonik kopolimerler ile uyumluluk, kartrmadan önce nötrletirme yoluyla salanabilir.
Filmlerin higroskopiklii: PVP / VA kopolimer filmlerin doal su hassasiyeti monomer oranna göre deiir. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-735, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-535 ve PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) E-335 için tipik veriler aada gösterilmitir . Genel olarak, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), PVP’den daha az higroskopiktir.
Kullanmlar
Tbbi
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) 1950’den sonra travma madurlar için plazma hacim geniletici olarak kullanlmtr. Histamin salnmn provoke etme ve ayn zamanda kan gruplamasna müdahale etme kabiliyeti nedeniyle hacim geniletici olarak tercih edilmemektedir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) birçok farmasötik tablette balayc olarak kullanlr; [2] azdan alndnda basitçe vücuttan geçer. (Bununla birlikte, otopsiler, krospovidonun (PVPP), oral tüketime yönelik farmasötik tabletleri enjekte eden madde bamllarnda pulmoner vasküler hasara katkda bulunduunu bulmutur. [3] Krospovidon veya povidonun akcier içindeki uzun vadeli etkileri bilinmemektedir.)
yoda eklenen PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), dezenfektan özelliklere sahip olan povidon-iyot ad verilen bir kompleks oluturur. [4] Bu kompleks, solüsyonlar, merhemler, peserler, sv sabunlar ve cerrahi frçalama gibi çeitli ürünlerde kullanlmaktadr. Pyodine ve Betadine ticari isimleri altnda, dierlerinin bolluu arasnda bilinir.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) plöredezde (sürekli plevral efüzyonlar nedeniyle plevrann füzyonu) kullanlr. Bu amaçla povidon iyot, talk kadar eit derecede etkili ve güvenlidir ve kolay bulunabilirlii ve düük maliyeti nedeniyle tercih edilebilir. [5]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) baz kontakt lenslerde ve bunlarn ambalajlama solüsyonlarnda kullanlmaktadr. Sürtünmeyi azaltr, böylece lensin içine yerletirilmi bir kayganlatrc veya slatc olarak ilev görür.
Teknik
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) tutkal çubuu ve scak eriyik yaptrclarda yaptrc olarak kullanlr.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), piller, seramikler, cam elyaf, mürekkepler ve mürekkep püskürtmeli katlar için özel bir katk maddesi olarak ve kimyasal-mekanik düzlemselletirme ileminde kullanlr.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), çözelti polimerizasyonu için emülgatör ve parçalayc olarak kullanlr.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), katot n tüpleri (CRT) için fotorezistlerde çözünürlük artnda kullanlr [9]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) sulu metal söndürmede kullanlr
diyaliz ve su artma filtreleri gibi membran üretimi için
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), bitki koruma, tohum ileme ve kaplama gibi tarmsal uygulamalarda balayc ve kompleksletirici ajan olarak kullanlr.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) di beyazlatma jellerinde kalnlatrc ajan olarak kullanlr [10]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), sv ve yar sv dozaj formlarnda (uruplar, yumuak jelatin kapsüller) ilaçlarn çözünürlüünü artrmaya yardmc olarak ve yeniden kristalleme inhibitörü olarak kullanlr.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), Doro’nun RNA ekstraksiyon tamponuna katk maddesi olarak kullanlr [kaynak belirtilmeli]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), DOSY NMR’de sv fazda dispersiyon arttrc ajan olarak kullanlr [11]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), nanopartikül sentezinde ve bunlarn kendiliinden birlemesinde yüzey aktif madde, indirgeme ajan, ekil kontrol ajan ve datc olarak kullanlr [12]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), tüm inorganik güne pillerinde stabilize edici bir ajan olarak kullanlmaktadr [13]
Dier kullanmlar
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), polaritesi nedeniyle polar moleküllere son derece iyi balanr. Bu, fotoraf kalitesinde mürekkep püskürtmeli katlar ve asetatlarn kaplamalarnda ve ayrca mürekkep püskürtmeli yazclar için mürekkeplerde uygulanmasna yol açmtr.
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), ampuanlar ve di macunlar gibi kiisel bakm ürünlerinde, eski tip posta pullar ve zarflar gibi nemlendirilmesi gereken boyalarda ve yaptrclarda da kullanlmaktadr. Kontakt lens çözümlerinde ve çelik söndürme çözümlerinde de kullanlmtr. [14] [15] PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), saç spreyleri ve saç jelleri için erken formüllerin temelidir ve hala bazlarnn bir bileeni olmaya devam etmektedir.
Bir gda katk maddesi olarak, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) bir stabilizatördür ve E1201 numarasna sahiptir. PVPP (krospovidon) E1202’dir. Ayn zamanda arap endüstrisinde beyaz arap ve baz biralar için inceltici ajan olarak kullanlr.
Moleküler biyolojide, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), Denhardt tamponunun bir bileeni olarak Southern blot analizi srasnda bloke edici bir ajan olarak kullanlabilir. Ayrca, DNA saflatrmas srasnda polifenolleri emmede son derece iyidir. Polifenoller birçok bitki dokusunda yaygndr ve uzaklatrlmazsa proteinleri etkisiz hale getirebilir ve bu nedenle PCR gibi birçok aa ak reaksiyonunu inhibe edebilir.
Mikroskopide, PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) sulu bir montaj ortam yapmak için kullanldr. [16]
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat), bitki özlerinin insülin üretimi üzerindeki etkisi üzerine 2000 ylnda yaplan bir çalmada referans olarak belirtildii gibi, fenolik özellikleri taramak için kullanlabilir.
PVP/VA W-635’in (Polivinilpirolidon Vinil Asetat) Güvenlii
ABD Gda ve laç Dairesi (FDA) bu kimyasal birçok kullanm için onaylamtr [18] ve genellikle güvenli kabul edilir. Bununla birlikte, PVP / povidona kar, özellikle deri alt (deri altna uygulanan) kullanm ve PVP/VA W-635’in (Polivinilpirolidon Vinil Asetat) otolog serumla (dahili kan) temas ettii durumlar ile ilgili olarak belgelenmi alerjik reaksiyon vakalar vardr. svlar) ve mukoza zarlar. Örnein, impetigo tedavisi için PVP-yot uygulandktan sonra anafilaktik yant veren bir erkek çocuun, çözeltinin PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) bileenine alerjisi olduu bulundu. [19] Daha önce çeitli saç ürünlerinden ürtiker (kurdeen) yaayan ve daha sonra PVP içerdii tespit edilen bir kadn, dahili olarak povidon-iyot solüsyonu uygulandktan sonra anafilaktik bir yant ald. PVP’ye alerjisi olduu bulundu. [20] Baka bir durumda, asetaminofen tabletlerini azdan aldktan sonra anafilaksi yaayan bir erkein PVP’ye alerjisi olduu bulundu. [21]
Povidon, genellikle dier kimyasallarla birlikte kullanlr. Baz hastalarda test sonuçlar üpheli kimyasala kar hiçbir alerji belirtisi göstermemesine ramen, iyot gibi bunlardan bazlar alerjik yantlardan sorumlu tutulmaktadr. Bu dier kimyasallara atfedilen alerjilere muhtemelen PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) neden olabilir. [22] [23]
PVP/VA W-635’in (Polivinilpirolidon Vinil Asetat) Özellikleri
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) suda ve dier polar çözücülerde çözünür. Örnein, metanol ve etanol gibi çeitli alkollerde [24] ve kolin klorür ve üre (Relin) tarafndan oluturulan derin ötektik çözücü gibi daha egzotik çözücülerde çözünür. [25] Kuruduunda hafif pulsu higroskopik bir tozdur ve arlnn% 40’na kadar atmosferik su içinde kolayca emilir. Çözelti olarak, mükemmel slatma özelliklerine sahiptir ve kolayca filmler oluturur. Bu, onu bir kaplama veya kaplamalara katk maddesi olarak iyi klar.
2014 ylnda yaplan bir çalmada, PVP/VA W-635’in (Polivinilpirolidon Vinil Asetat) ve oksitlenmi hidrolizatnn floresan özellikleri bulundu.
PVP/VA W-635 Tarihçesi (Polivinilpirolidon Vinil Asetat)
PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) ilk olarak Walter Reppe tarafndan sentezlenmi ve asetilen kimyasnn türevlerinden biri için 1939’da bir patent bavurusu yaplmtr. PVP/VA W-635 (Polivinilpirolidon Vinil Asetat) balangçta bir kan plazma ikamesi olarak ve daha sonra tp, eczaclk, kozmetik ve endüstriyel üretimde çok çeitli uygulamalarda kullanld.