NEOPENTYL GLYCOL

Table of Contents

NEOPENTYL GLYCOL

NEOPENTIL GLYCOL (NEOPENTL GLKOL)

CAS NO: 126-30-7


METATAGS;2,2-dimethyl-1,3-propanediol;Neopentyl glycol;2,2-Dimethylpropane-1,3-diol;126-30-7;2,2-DIMETHYL-1,3-PROPANEDIOL;Dimethylolpropane;Neopentylene glycol;Neopentanediol;Neopentylglycol;Neol;1,3-Propanediol, 2,2-dimethyl-;Hydroxypivalyl alcohol;Dimethyltrimethylene glycol;2,2-Dimethyltrimethylene glycol;UNII-QI80HXD6S5;NPG Glycol;NSC 55836;2,2-Dimethyl-1,3 propanediol;EINECS 204-781-0;Propanediol, 2,2-dimethyl-, 1,3-;BRN 0605291;AI3-05739;2,3 propanediol;SLCVBVWXLSEKPL-UHFFFAOYSA-N;SBB056814;DSSTox_CID_7036;DSSTox_RID_78285;DSSTox_GSID_27036;WLN: Q1X1 & 1 & 1Q;CAS-126-30-7;2,2-dimethylolpropane;AC1L1LFZ;AC1Q1NLU;ACMC-1C2GC;QI80HXD6S5;SCHEMBL19621;CBDivE_004836;4-01-00-02551 (Beilstein Handbook Reference);KSC177Q9P;2,2-Bis(hydroxymethyl)propane;2,2-dimethyl-1,3-propandiol;2,2-dimethylpropan-1,3-diol;2,2-dimethyl 1,3-propanediol;2.2-dimethyl-1,3-propanediol;2,3-Dimethyl-1,3-propanediol;CHEMBL3184801;DTXSID8027036;CTK0H7897;2,2-dimethyl -1,3-propanediol;2,2-dimethyl-1,3-propane diol;2,2-dimethyl-propane-1,3-diol;NSC6366;MolPort-003-932-306;ZINC388175;NSC-6366;NSC55836;1,3-Dihydroxy-2,2-dimethylpropane;2,2-Dihydroxy-2,2-dimethylpropane;2,2-Dimethyl-1,3-dihydroxypropane;Tox21_201363;Tox21_303298;ANW-18922;MFCD00004685;NSC-55836;ZINC00388175;AKOS005068060;MCULE-3663555151;NE10344;RL01297;RTR-003853;TRA0083916;2,2-Dimethyl-1,3-propanediol, 99%;NCGC00249034-01;NCGC00256980-01;NCGC00258915-01;AJ-20472;AK109182;AN-22975;CJ-03141;I936;KB-16396;OR012210;OR112803;SC-79890;ZB011337;LS-120360;ST2415601;TR-003853;D0791;FT-0653714;ST50982294;31682-EP2295399A2;31682-EP2308858A1;31682-EP2311816A1;31682-EP2311817A1;55473-EP2270101A1;55473-EP2284165A1;55473-EP2292597A1;55473-EP2301919A1;55473-EP2301924A1;55473-EP2308865A1;55473-EP2374895A1;218793-EP2371805A1;218793-EP2374787A1;I14-2699;J-506805;F0001-0385;Z1235963404;InChI=1/C5H12O2/c1-5(2,3-6)4-7/h6-7H,3-4H2,1-2H;111109-35-4;1,3-Propanediol, 2,2-dimethyl- [ACD/Index Name];2,2-Dimethyl-1,3-propandiol [German] [ACD/IUPAC Name];2,2-Dimethyl-1,3-propanediol [ACD/IUPAC Name];2,2-Diméthyl-1,3-propanediol [French] [ACD/IUPAC Name];2,2-dimethylpropane-1,3-diol;Neopentyl glycol [Wiki];1,3-Dihydroxy-2,2-dimethylpropane;126-30-7 [RN];2,2-Dimethyl-1,3 propanediol,2,2-Dimethyl-1,3-dihydroxypropane;2,2-Dimethyl-1,3-Propanediol (en);2,2-Dimethyltrimethylene glycol;2,3-Dimethyl-1,3-propanediol;204-781-0 [EINECS];2-ethylpropane-1,3-diol;4-01-00-02551 (Beilstein Handbook Reference) [Beilstein];DIMETHYLTRIMETHYLENE GLYCOL;Hydroxypivalyl alcohol;MFCD00004685 [MDL number];Neol;Neopentanediol;Neopentylene glycol;Neopentylglycol;NPG;NPG Glycol;propane-1,3-diol, 2,2-dimethyl-;Propanediol, 2,2-dimethyl-, 1,3-;Q1X1 & 1 & 1Q [WLN];UNII:QI80HXD6S5;UNII-QI80HXD6S5;Neopentyl glycol mixed steartates and myristates;Neopentyl glycol ester of myristic and stearic acids;Octadecanoic acid,mixed esters with myristic acid and neopentyl glycol;1,3-Propanediol, 2,2-dimethyl;Neol;NEOL(R);NPG Glycol;Neopentanediol;NEOPENTYL GLYCO;NEOPENTYL GLYCOL;Dimethylolpropane;NEOPENTYLENE GLYCOL;hydroxypivalylalcohol;NEOPENTYL GLYCOL pure;2-METHOXY-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE Unsaturated polyester resin 5-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-CHLORO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE Ibuprofen 3-METHOXY-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 4-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-(TRIFLUOROMETHYL)-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-CYANO-5-BROMOPHENYLBORONIC ACID PINACOL ESTER Sodium formate 2-BROMO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE ISOQUINOLINE-4-BORONIC ACID 2,2-DIMETHYLPROPANEDIOL-1,3 CYCLIC ESTER Triethylene glycol dimethacrylate 4-CHLORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 3-FLUORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE;Diethylene glycol Trimethylol propane Dimethyl fumarate Dimethyl sulfate N,N-Dimethylformamide 1-Methoxy-2-propanol PROPYLENE GLYCOL 1,3-Propanediol Bis(neopentyl glycolato)diboron Poly(propylene glycol) 1,4-Butanediol 2-Methyl-2,4-pentanediol Dimethyl disulfide Ethylene glycol diacetate Ethylene glycol Propylene glycol 2-METHYL-1,3-PROPANEDIOL 1-Phenoxy-2-propanol;1,3-Dihydroxy-2,2-dimethylpropane 1,3-propanediol,2,2-dimethyl- 2,2-Dimethyl-1,3-dihydroxypropane 2,2-dimethyl-3-propanediol 2,2-Dimethylpropane-1,3-diol 2,2-dimethyltrimethyleneglycol 3-Propanediol,2,2-dimethyl-1 Dimethylolpropane Hydroxypivalyl alcohol hydroxypivalylalcohol Neol Neopentanediol NPG Glycol DIMETHYLTRIMETHYLENE GLYCOL Building Blocks 126-30-7 2,2-BIS(HYDROXYMETHYL)PROPANE 2,2-DIHYDROXY-2,2-DIMETHYLPROPANE 2,2-DIMETHYL-1,3-PROPANEDIOL NEOPENTYLENE GLYCOL NEOPENTYL GLYCOL NEOL(R) Polyols Oxygen Compounds Organic Building Blocks NEOPENTYL GLYCO 2,2-DIMETHYL-1,3-PROPANEDIOL (NPG) 2,2-Dimethyl-1,3 propandiol CH32CCH2OH2 2,2-dimethyl-1,3-propanediol (Neopentyl Glycol) Intermediates of Dyes and Pigments 2,2-Dimethylpropan-1,3-diol 126307 Organics 2,2-DIMETHYL-1,3-PROPANEDIOL 99.5+% HOCD2CCD32CD2OH NEOPENTYL GLYCOL pure Neopentylglycol, NPG Glycol 2,2-Dimethyl-1,3-propanediol,99% 2,2-Dimethyl-1,3-propanediol,97% neopentyl glycol(2,2-dimethyl-1,3-propanedil) 2,2-Dimethyl-1,3-propanediol,NPG Glycol, Neopentylglycol Neopentyl Glycol (Slurry and Flake) 2,2-DiMethyl-1,3-propanediol, 99% 25GR 2,2-DiMethyl-1,3-propanediol, 99% 500GR 2,2-Bis(hydroxymethyl)propane 2,2-Dihydroxy-2,2-dimethylpropane Neopentyl Glycol 2,2-DIMETHYL-1,3-PROPANEDIOL FOR SYNTHES Neopentyl glycol (NPG) 2,2-DiMethyl-1,3-propanediol 99% 2,2-DiMethyl-1,3-propanediol, 99.5%, 99.5% Neopentylglycol flakes Pyridines 2,2-Dimethyl-1,3-propanediol(NPG Glycol);Neopentyl glycol;2,2-Bis(hydroxymethyl)propane;2,2-Dihydroxy-2,2-dimethylpropane;Neopentyl Glycol;2,2-dimethyl propane-1,3-diol;dimethyl trimethylene glycol;2,2-dimethyl-1,3-propane diol;2,2-dimethyl-1,3-propanediol;dimethylol propane;2,2-dimethylpropane-1,3-diol;dimethyltrimethylene glycol;hydroxypivalyl alcohol;NPG glycol;neopentane diol;neopentylene glycol;neopentylglycol;propane-1,3-diol, 2,2-dimethyl-;1,3-propanediol, 2,2-dimethyl-;Neopentyl glycol; 2,2-dimethylpropane-1,3-diol; 2-ethylpropane-1,3-diol;2,2-Dimethyl-1,3-propanediol; Neoppentylglycol; 1,3-Dihydroxy-2,2-dimethylpropane; 2,2-Bis(hydroxymethyl)propane; 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethyl-1,3-propanediol; 2,2-Dimethyl-1,3-propylene Glycol; 2,2-Dimethylolpropane; 2,2-Dimethylpropan-1,3-diol; 2,2-Dimethylpropanediol Monoacrylate Monomethacrylate; 2,2-Dimethyltrimethylene Glycol; Dimethylolpropane; Hydroxypivalyl Acohol; NSC 55836; NSC 6366; Neopentanediol; Neopentyl Glycol; Neopentylene Glycol; Nexcoat 600;NPG Glycol; Neopentylglycol;Neopentylene glycol; 1,3-Propanediol, 2,2-dimethyl-; 2,2-Dimethyl-1,3-propanediol;Neopentil glikol nedir,neopentil glikol nerede kullanlr,nerelerde kullanlr,neopentil glikol kullanm,neopentil glikol hangi alanlarda kullanlr,neopentil glikol kimyasal özellikleri,fiziksel özellikleri,neopentil hangi alanlarda kullanlr,neopentil glikol teknik özellikleri,neopentil glikol kimyasal formülü,neopentil glikol speskti,spesifikasyonu,güvenlik bilgi formu,neopentil glikol teknik artnamesi;NEOPENTYL GLYCOL;2,2-DIMETHYL-1,3-DIHYDROXYPROPANE;2,2-DIMETHYL-1,3-PROPANEDIOL;1,3-PROPANEDIOL, 2,2-DIMETHYL-;DIMETHYLOLPROPANE;2,2-DIMETHYLTRIMETHYLENE GLYCOL;2,2-BIS(HYDROXYMETHYL)PROPANE;2,2-Dimethyl-1,3-propanediol may be used in the synthesis of:;2,2-dimethyl-1,3-propanediol cyclic phosphorochloridate[1];2,2-dimethyl-1,3-propanediol cyclic phenylphosphonate[1];[1′,3′-(2′,2′-dimethylpropylene)]-2-iodo-3-octyl-5-thienylboronate[2];cyclic carbonate[3];2,2-dimethyl-1,3-propanediol bis(cyclic-2,2-dimethyltrimethylene phosphite);1,3-Benzodioxole, 2,2-dimethyl- [ACD/Index Name];2,2-Dimethyl-1,3-benzodioxol [German] [ACD/IUPAC Name];2,2-Dimethyl-1,3-benzodioxole [ACD/IUPAC Name];2,2-Diméthyl-1,3-benzodioxole [French] [ACD/IUPAC Name];[14005-14-2];1,2-(Isopropylidenedioxy)benzene;14005-14-2 [RN];2,2-DIMETHYL-1,3-BENZODIOXAZOLE;2,2-dimethyl-2H-1,3-benzodioxole;2,2-Dimethylbenzo[d][1,3]dioxole;2,2-dimethylbenzo[d]1,3-dioxolane;MFCD08061594 [MDL number];NEOPENTIL GLIKOL;NEOPENTILGLIKOL;NEOPENTL GLKOL;NEOPENTLGLKOL;NEO PENTIL GLIKOL;NEO PENTL GLKOL;NEO PENTIL GLYCOL;NEOPENTILGLYCOL;NEO PENTIL GILIKOL;NEOPENTIL GILIKOL;NEOPENTILGILIKOL;NEO PENTL GLKOL;NEOPENTLGLKOL;neopentl glkol;neopentlglkol;neopentil glikol;neopentilglikol;neo pentil glikol;neo pentl glkol;neo perntl glycol;neopentlglycol;neopentlglkol;neopentl glkol;neopentlglkol;neopentyl glycol;neo pentyl glycol;neopentylglycol;NEOPENTYL GLYCOL;NEO PENTYL GLYCOL;NEOPENTYLGLYCOL;2,2-dimetilpropan_1,3_diol;2,2-Dimethyl-1,3-propanediol;2,2-Dimethylpropane-1,3-diol;1,3-Dihydroxy-2,2-dimethylpropane

 

EC NUMBER: 204-781-0

Molecular Formula of Neopentyl Glycol
C5H12O2

IUPAC Name of Neopentyl Glycol
2,2-dimethylpropane-1,3-diol

Experimental Properties of Neopentyl Glycol
Physical Description of Neopentyl Glycol
2,2-DIMETHYLPROPANE-1,3-DIOL is a white crystalline solid. Melting point 130°C.

Liquid
Liquid, PelletsLargeCrystals
OtherSolid
OtherSolid, PelletsLargeCrystals, WetSolid
PelletsLargeCrystals

Boiling Point of Neopentyl Glycol
406.4° F at 760 mm Hg

Melting Point of Neopentyl Glycol
260.6° F

Flash Point of Neopentyl Glycol
225° F

Density v
1.1 g/cm³


Chemical Properties of Neopentyl Glycol
white solid
Uses of Neopentyl Glycol
NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator.
General Description of Neopentyl Glycol
White crystalline solid.
Air & Water Reactions
Soluble in water.
Reactivity Profile of Neopentyl Glycol
2,2-Dimethyl-1,3-propanediol may generate toxic gases in combination of with alkali metals, nitrides, and strong reducing agents. Reacts with inorganic acids and carboxylic acids to form esters plus water. Converted to aldehydes or acids by oxidizing agents. May initiate the polymerization of isocyanates and epoxides.

2,2-Dimethyl-1,3-propanediol readily absorbs moisture on exposure to air.

Used for protection of carbonyl groups as 4,4-dimethyl-1,3-dioxanes, often preferred to the more usual 1,3-dioxolanes due to easier separation and greater stability, for protection of carbonyl group of 4-bromo-2-propanone using p-toluenesulfonic acid in the presence of triethyl orthoformate. It is used in the synthesis of polyesters, paints, lubricants, and plasticizers.

Especially used in paint and coating resin production, gelcoat and powder coating. A very limited amount is converted into esters and used in aircraft engine oil production.


Polyol synthesized by the reaction of isobutyraldehyde with formaldehyde. It is a raw material for polyester resins.

 

 

Neopentyl glycol (IUPAC name: 2,2-dimethylpropane-1,3-diol) is an organic chemical compound. It is used in the synthesis of polyesters, paints, lubricants, and plasticizers. 

When used in the manufacture of polyesters, it enhances the stability of the product towards heat, light, and water. 

By esterification reaction with fatty or carboxylic acids, synthetic lubricating esters with reduced potential for oxidation or hydrolysis, compared to natural esters, can be produced.

 

Other names: 1,3-Propanediol, 2,2-dimethyl-; Dimethylolpropane; Neopentanediol; Neopentylene glycol; 2,2-Dimethyl-1,3-propanediol; Dimethyltrimethylene glycol; Hydroxypivalyl alcohol; NPG; Neol; 1,3-Dihydroxy-2,2-dimethylpropane; 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethylpropane-1,3-diol; NPG Glycol; 2,2-Dimethyltrimethylene glycol; NSC 55836

 

Synonyms: 1,3-Propanediol, 2,2-dimethyl-; 2,2-Dimethyl-1,3-propanediol; 2,2-Dimethyltrimethylene glycol; Dimethylolpropane; Dimethyltrimethylene glycol; Hydroxypivalyl alcohol; Neol; Neopentanediol; Neopentylene glycol; NPG; 2,2-Dimethylpropane-1,3-diol; Propanediol, 2,2-dimethyl-, 1,3-; [ChemIDplus] Dimethylol propane; [CAMEO] 1,3-Dihydroxy-2,2-dimethylpropane; [ICSC] 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethylolpropan; 2,2-Dimetil-1,3-propandiolo; Dimetilolpropano; Neopentilene glicole; Neopentilglicole; Neopentylglycol; Neopentylglykol; Pentaglycol; [IUCLID]

 

Category

Alcohols and Polyols, Other

 

Description

Colorless to white hygroscopic solid; [ICSC] White hygroscopic crystals with a mild odor; 

 

Sources/Uses

Used to make plasticizers and polyesters and as modifier of alkyd resins; Used in chemical synthesis and in the polymers industry; [IUCLID] Used to make large scale and fine chemicals, rubber products, plastic products, textiles, leather, fur, wood and wood products, pulp-paper and paper products, non-metallic mineral products (i.e. plasters and cement), in printing and reproduction of recorded media, building and construction work, scientific research and development, and consumer construction chemicals; [ECHA REACH Registrations]

 

Key Applications

Polyester coatings; gel coatings; synthetic marble; polyurethane coatings; synthetic lubricants

 

Product Description

This functional glycol can be used as an intermediate for both plasticizers and for synthetic lubricants. In most polyester resin formulations, it is used as the sole glycol component. It offers excellent thermal stability, weathering, and stain resistance. 

 

Uses

Neopentyl glycol (NPG) is used primarily in base resins for coatings. Important uses are also found in hydraulic fluids, synthetic lubricant oils, greases, metal-working fluids and aircraft engine lubricants. Other outlets include textiles, pharmaceuticals, pesticides, plasticisers and petroleum. NPG is shipped as flake, molten and slurry.

 

Main Applications: Alkyd resin paint, polyester resin, powdered paint

 

Neopentyl glycol, also known as Dimethylolpropan, is a colorless-to-white, hygroscopic crystalline, organic chemical compound that is used in the synthesis of paints, polyesters, lubricants, and plasticizers.  The combustible, slightly toxic compound can be harmful if ingested or is absorbed through skin contact. It is known to cause skin and eye irritation.

 

The chemical formula for Neopentyl glycol is C5H12O2. Its CAS is 126-30-7. The crystalline substance is synthesized industrially by the aldol reaction of formaldehyde and isobutyraldehyde, which creates the intermediate hydroxypivaldehyde. This can be converted to Neopentyl glycol with either excess formaldehyde or catalytic hydrogenation of the aldehyde group to an alcohol group.

 

Neopentyl glycol is soluble in water, benzene, chloroform, and very soluble in ethanol and diethyl ether.

 

The industrial uses for the combustible organic compound include dyes, functional fluids in closed systems, intermediates, lubricants and lubricant additives, paint and coating additives, and processing aids specific to petroleum production.

 

Consumer uses include adhesives and sealants, paints and coatings, and paper products.

 

Supply/demand

Global capacity stood at 485,000 tonnes/year in 2005, with 173,000 tonnes/year in western Europe, 140,000 tonnes/year in the US, 134,000 tonnes/year in Asia-Pacific (excluding Japan) and 38,000 tonnes/year in Japan, according to consultancy TranTech.

 

Western Europe is the largest consumer at about 118,000 tonnes/year, followed by the US at 108,000 tonnes/year and Asia-Pacific at 94,000 tonnes/year. Japan, Latin America and the Middle East consume 25,700 tonnes/year, 10,500 tonnes/year and 9,250 tonnes/year, respectively. Western Europe and the US are the world’s biggest exporters at 31,000 tonnes/year and 16,300 tonnes/year, respectively. Asia-Pacific was a net importer in 2005 by 5,500 tonnes.

 

Neopentyl glycol is an organic chemical synthesized by aldol reaction of formaldehyde and isobutyraldehyde. It is majorly used in the synthesis of plasticizers, paints, lubricants and polyester resins. The product has wide applications in several industries including construction, aerospace, automotive, paints and coatings, consumer products and electronic applications. The significant growth in market as a result of enhanced properties of the product will create new avenues for the manufacturers in forecasted time frame. Overall growth in construction industry, increasing demand for consumer goods and automotive in the emerging economies will boost the neopentyl glycol market expansion.

 

Technology

There are two main routes to NPG using isobutyraldehyde and formaldehyde. In one, the raw materials react with a strongly alkaline catalyst to form NPG. But, large amounts of formate salts are formed as byproduct and the process is only economically viable when a profitable use is found for the formate.

 

In a second and more common process, the aldolisation reaction is carried out in the presence of an amine catalyst. This is further hydrogenated in the presence of a catalyst and the molten NPG is solidified by means of a flaking roll, or a crystallising or cooling belt.

 

Health and safety

NPG is a white, crystalline solid with a mint-like odour. Finely dispersed particles form explosive mixtures in air and it reacts violently with oxidants.

 

Formula: C5H12O2 / (CH3)2C(CH2OH)2

Molecular mass: 104.2

Boiling point: 210°C

Melting point: 127°C

Density: 1.1 g/cm³

Solubility in water, g/100ml at 20°C: 83

Vapour pressure, Pa at 20°C: 30

Relative vapour density (air = 1): 3.6

Relative density of the vapour/air-mixture at 20°C (air = 1): 1.0

Flash point: 107°C

Auto-ignition temperature: 388°C

Explosive limits, vol% in air: 1.1-11.4

Octanol/water partition coefficient as log Pow: -0.84  

 

 

Physical State; Appearance

COLOURLESS-TO-WHITE HYGROSCOPIC CRYSTALS. 

 

Physical dangers

Dust explosion possible if in powder or granular form, mixed with air. 

 

Chemical dangers

Reacts violently with oxidants. 

 

 

 

1,3-Propanediol, 2,2-dimethyl- [ACD/Index Name]

126-30-7 [RN]

2,2-Dimethyl-1,3-propandiol [German] [ACD/IUPAC Name]

2,2-Dimethyl-1,3-propanediol [ACD/IUPAC Name]

2,2-Diméthyl-1,3-propanediol [French] [ACD/IUPAC Name]

2,2-dimethylpropane-1,3-diol

204-781-0 [EINECS]

4-01-00-02551 [Beilstein]

MFCD00004685 [MDL number]

Neopentanediol

Neopentyl glycol [Wiki]

Neopentylene glycol

Neopentylglycol

NPG Glycol

Propanediol, 2,2-dimethyl-, 1,3-

QI80HXD6S5

TY5775000

UNII-QI80HXD6S5

1,3-Dihydroxy-2,2-dimethylpropane

2, 2-Dimethyl-1, 3-propanediol

2,​2-​dimethylpropane-​1,​3-​diol

2,2-Dimethyl-1,3 propanediol

2,2-Dimethyl-1,3-dihydroxypropane

2,2-Dimethyltrimethylene glycol

2,3-Dimethyl-1,3-propanediol

2-ethylpropane-1,3-diol

Dimethyltrimethylene glycol

https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:143768

Hydroxypivalyl alcohol

Neol

NPG

propane-1,3-diol, 2,2-dimethyl-

Q1X1 & 1 & 1Q [WLN]

 

 

 

Preferred IUPAC name

2,2-Dimethylpropane-1,3-diol

2,2-Dimethyl-1,3-propanediol

 

CAS Number: 126-30-7 

 

Reactions

Neopentyl glycol is synthesized industrially by the aldol reaction of formaldehyde and isobutyraldehyde. 

This creates the intermediate hydroxypivaldehyde, which can be converted to neopentyl glycol with either excess formaldehyde or by palladium on carbon hydrogenation. 

 

It is used as a protecting group for ketones, for example in gestodene synthesis.

 

A condensation reaction of neopentyl glycol with 2,6-di-tert-butylphenol gives CGP-7930.

 

Organoboronic acid esters of neopentyl glycol are useful in the Suzuki reaction

 

It has been reported that plastic crystals of neopentyl glycol exhibit a colossal barocaloric effect (CBCEs), which is a cooling effect caused by pressure-induced phase transitions. 

The obtained entropy changes are about 389 joules per kilogram per kelvin near room temperature. 

This CBCE phenomenon is likely to be very useful in future solid-state refrigeration technologies.

 

Chemical formula: C5H12O2

Molar mass:104.148 g/mol

Melting point: 129.13 °C (264.43 °F; 402.28 K)

Boiling point: 208 °C (406 °F; 481 K)

Solubility in water:good

Solubility: soluble in benzene, chloroform, very soluble in ethanol, diethyl ether

 

 

1,3-Propanediol, 2,2-dimethyl-

2,2-Dimethyl-1,3-propanediol

2,2-dimethyl-1,3-propanediol

2,2-dimethylpropane-1,3-diol

 

EC Inventory

2,2-dimethylpropane-1,3-diol

2,2-Dimethyltrimethylene glycol

Dimethylolpropane

Dimethyltrimethylene glycol

Hydroxypivalyl alcohol

Neol

Neopentanediol

Neopentyl glycol

Neopentylene glycol

NPG

 

CAS names

1,3-Propanediol, 2,2-dimethyl-

Other

IUPAC names

1,3-Propanediol, 2,2-dimethyl-

2,2-Dimethyl-1,3-propanediol

2,2-dimethyl-1,3-Propanediol

2,2-dimethyl-1,3-propanediol

2,2-dimethylpropan-1,3-diol

C&L Inventory

2,2-Dimethylpropane-1,3-diol, Other

2,2-dimethylpropane-1,3-diol, Other

2,2-dimethylpropane-1,3-diol, Other

2,2-dimethylpropane-1,3-diol (neopentyl glycol)

NEOPENTYL GLYCOL

Neopentyl Glycol

Neopentyl glycol

NEOPENTYL GLYCOL

Neopentyl glycol

Neopentyl Glycol (NPG)

Neopentylglycol

propylene glycol

 

Trade names

1,3-Dihydroxy-2,2-dimethylpropane

1,3-Propanediol, 2,2-dimethyl- (6CI, 7CI, 8CI, 9CI)

2,2-Dimethyl-1,3-dihydroxypropane

2,2-Dimethyl-1,3-propanediol

2,2-Dimethyltrimethylene glycol

Dimethylolpropane

Fomrez Series

Hydroxypivalyl alcohol

Neo Pentyl glycol

Neopentanediol

Neopentil Glicole

Neopentyl glycol

Neopentylene glycol

Neopentylglykol

NPG

VIBRATHANE Series

Witcobond Series

 

 

Neopentyl glycol

126-30-7

2,2-Dimethylpropane-1,3-diol

2,2-DIMETHYL-1,3-PROPANEDIOL

Dimethylolpropane

1,3-Propanediol, 2,2-dimethyl-

Neopentanediol

Neopentylene glycol

Neopentylglycol

Neol

Hydroxypivalyl alcohol

 

Dimethyltrimethylene glycol

NPG Glycol

2,2-Dimethyltrimethylene glycol

UNII-QI80HXD6S5

NSC 55836

CCRIS 3273

2,2-Dimethyl-1,3 propanediol

NPG

EINECS 204-781-0

Propanediol, 2,2-dimethyl-, 1,3-

BRN 0605291

QI80HXD6S5

AI3-05739

2,3 propanediol

1,3-Dihydroxy-2,2-dimethylpropane

2,2-Dimethyl-1,3-propanediol, 99%

WLN: Q1X1 & 1 & 1Q

CAS-126-30-7

2,2-Bis(hydroxymethyl)propane

MFCD00004685

2,2-dimethylolpropane

ACMC-1C2GC

EC 204-781-0

SCHEMBL19621

CBDivE_004836

4-01-00-02551 (Beilstein Handbook Reference)

KSC177Q9P

2,2-dimethyl-1,3-propandiol

2,2-dimethylpropan-1,3-diol

2,2-dimethyl 1,3-propanediol

2.2-dimethyl-1,3-propanediol

2,3-Dimethyl-1,3-propanediol

2,2-dimethyl -1,3-propanediol

2,2-dimethyl-1,3-propane diol

2,2-dimethyl-propane-1,3-diol

2,2-Dihydroxy-2,2-dimethylpropane

2,2-Dimethyl-1,3-dihydroxypropane

Tox21_201363

 

 

1,3-Dihydroxy-2,2-dimethylpropane

1,3-Propanediol, 2,2-dimethyl- (6CI, 7CI, 8CI, 9CI)

2,2-Dimethyl-1,3-dihydroxypropane

2,2-Dimethyl-1,3-propanediol

2,2-Dimethyltrimethylene glycol

Dimethylolpropane

Fomrez Series

Hydroxypivalyl alcohol

NPG

Neo Pentyl glycol

Neopentanediol

Neopentyl glycol

Neopentylene glycol

Neopentylglykol

VIBRATHANE Series

Witcobond Series

 

 

 

 

 

 

 

 

 

 

 


EC NUMARASI: 204-781-0

Neopentil Glikolün Moleküler Formülü
C5H12O2

Neopentil Glikolun Ad: IUPAC
2,2-dimetilpropan-1,3-diol;

Neopentil Glikolün Deneysel Özellikleri
Neopentil Glikolün Fiziksel Tanm
2,2-DMETLPROPAN-l, 3-DOL, beyaz bir kristalimsi katdr. Erime noktas 130 ° C.

Sv
Sv, PelletLarj Kristalleri
OtherSolid
DierleriHarici, PelletlerLargeCrystaller, WetSolid
PelletsLargeCrystals

Neopentil Glikol Kaynama Noktas
760 mm Hg’de 406.4 ° F

Neopentil Glikol Ergime Noktas
260.6 ° F

Neopentil Glikolün Parlama Noktas
225 ° F

Younluk v
1,1 g / cm³


Neopentil Glikolün Kimyasal Özellikleri
Beyaz kat
Neopentil Glikol Kullanm
NPG Glikol, tetrafenilporfirinlerin sentezinde kullanlr. Ayrca bir protein kinaz modülatörü olan Bryostatin 2 sentezinde de kullanlr.
Neopentil Glikolun Genel Açklamas
Beyaz kristal kat.
Hava ve Su Reaksiyonlar
Suda çözünür.
Neopentil Glikolün Reaktivite Profili
2,2-Dimetil-l, 3-propandiol, alkali metaller, nitrürler ve kuvvetli indirgeme maddeleri ile kombinasyon halinde zehirli gazlar üretebilir. Asit ve su oluturan inorganik asitler ve karboksilik asitlerle reaksiyona girer. Oksitleyici maddeler ile aldehitlere veya asitlere dönütürülür. zosiyanatlarn ve epoksitlerin polimerizasyonunu balatabilir.

2,2-Dimetil-l, 3-propandiol havaya maruz kaldkça nemi kolaylkla emer.

4-bromo-2-karboksilik asidin karbonil grubunun korunmas için karbonil gruplarnn daha kolay ayrlma ve daha fazla kararllk nedeniyle genellikle olaan 1,3-dioksolanlara tercih edilen 4,4-dimetil-1,3-dioksanlar olarak korunmas için kullanlr. Propanon ile trietil ortoformat varlnda p-toluensulfonik asit kullanlarak hazrlanr. Polyester, boya, yalayc ve plastikletiricilerin sentezinde kullanlr.

Özellikle boya ve kaplama reçinesi üretimi, jelkot ve toz boyalarda kullanlr. Çok snrl bir miktar esterlere dönütürülür ve uçak motor ya üretiminde kullanlr.


zobütiraldehidin formaldehit ile reaksiyona girmesiyle sentezlenen poliol. Polyester reçinelerin hammaddesidir.

 

 

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