GLYOXAL 40 (GLOKSAL 40)
Glyoxal 40 (Glioksal 40)
CAS No: 107-22-2
EC No: 203-474-9
synonyms:
Glioksal 40; Glioksal 40%; Ethanedial; 107-22-2; GLOKSAL 40; GLOKSAL 40%; Oxalaldehyde; oxaldehyde; 1,2-Ethanedione; Glyoxylaldehyde;Diformyl; Biformal; Biformyl; Diformal; Aerotex glyoxal 40; Glyoxal aldehyde; Ethanedial, trimer; Ethanediol, trimer; Glyoxal, 40%; Glyoxal solution; Glyoxal solutions; CCRIS 952; UNII-50NP6JJ975; Ethane-1,2-dione; C2H2O2; HSDB 497; Glyoxal, 29.2%; EINECS 203-474-9; Glyoxal, 40% in water; BRN 1732463; AI3-24108; CHEBI:34779; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; Ethane-1,2-dione; C2H2O2; HSDB 497; Glyoxal, 29.2%; EINECS 203-474-9; Glyoxal, 40% in water; BRN 1732463; AI3-24108; CHEBI:34779; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; MFCD00006957; NCGC00091228-01; DSSTox_CID_5364; DSSTox_RID_77764; DSSTox_GSID_25364; 40094-65-3; Ethanedione; CAS-107-22-2; Glyoxal solution, ~40% in H2O (~8.8 M); bisformyl; oxypolygelatine; Gelifundol; Oxypolygelatin; Ethandial; Glycoxal; Glyfosfin; ethane dial; (oxo)acetaldehyde; ethane-1,2-dial; Protectol GL 40; ODIX; NSC 262684; AC1L1PPU; ACMC-1BV6U; Glyoxal, 40 % Solution; Glyoxal solution, 40.0%; 4-01-00-03625 (Beilstein Handbook Reference); BIDD:ER0284; (CHO)2; AC1Q28J9; Glyoxal, Biformyl, Oxalaldehyde; CHEMBL1606435; DTXSID5025364; CTK0H4953; Glyoxal, 40% w/w aq. soln.; MolPort-001-780-154; 50NP6JJ975; BB_SC-7204; ZINC8437750; Tox21_111105; Tox21_202517; NW-43524; BBL011519; LS-36; NSC262684; STL146635; AKOS000119169; Glyoxal solution, 40 wt. % in H2O; MCULE-3212938778; NSC-262684; RP18241; RTR-001406; TRA0067179; KS-00000V42; GLYOXAL, 76%, POWDER (TRIMER); NCGC00260066-01; AN-22473; KB-52297; OR034237; OR369233; SC-19118; Glyoxal solution, CP, 40 wt. % in H2O; TR-001406; FT-0626792; G0152; X8004; Glioxaldehit; etandial, 1,2-Etandiol; Diformil; Etandione; Glioxal aldehit; C14448; Glyoxal solution, 40 wt. % in water 100ml; 57421-EP2269977A2; 57421-EP2270006A1; 57421-EP2289896A1; 57421-EP2308878A2; 57421-EP2377845A1; Gelatins, reaction products with glyoxal, oxidized; J-001740; S14-1487; F2191-0152; Glyoxal solution, ~40% in H2O, for HPLC derivatization; Glyoxal solution, BioReagent, for molecular biology, ~40% in H2O (~8.8 M); 83513-30-8; 9005-91-8; Ethanedial; Ethanedione; Glyoxal; 40094-65-3; 1162; 262684; MD2700000; 2810; 50NP6JJ975; Oxaldehyde; InChI=1S/C2H2O2/c3-1-2-4/h1-2H; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; C(=O)C=O; OHCCHO; 1,2-Ethanedione; Diformal; ethandial; Ethanedial; Ethanedione; MFCD00006957; Oxalaldehyd; Oxalaldehyde; GXT; ODIX; oxal; Protectol GL 40; trans-glyoxal; UNII:50NP6JJ975; EDO; Gelifundol; gliksol; glioksal; gilioksal; gilioxal; glioxal; glyoksal; glyoxale; glioksale; glyoxal; ODIX; Oxal; (CHO)2; GLYOXA; GLYOXAL; DIFORMYL; Biformal; Biformyl; Diformal; GLYOXALE; CB1280241; InChIKeyLEQAOMBKQFMDFZ-UHFFFAOYSA-N; NIST Chemistry Reference; Ethanedial(107-22-2); Glyoxal; (Ethanedione, 1, 2-) (107-22-2); AEROTEX GLYOXAL 40; BIFORMAL; BIFORMYL; DAICEL GY 60; DIFORMAL; DIFORMYL; ETHANDIAL; ETHANEDIAL; ETHANEDIOL; ETHANEDIONE; 1,2-ETHANEDIONE; GLYFIX CS 50; GLYOXAL; GLYOXAL ALDEHYDE; GLYOXAL, 40% SOLUTION; GLYOXYLALDEHYDE; GOHSEZAL P; OXAL; OXALALDEHYDE; OXALDEHYDE; PERMAFRESH 114; MFCD00006957; Biformyl; Ethanedial; 1,2-Ethanedione; Oxalaldehyde; Ethanedial; Biformal; Biformyl; Diformyl; Ethanedione; Glyoxal aldehyde; Glyoxylaldehyde; Oxal; Oxalaldehyde; 1,2-Ethanedione; (CHO)2; Diformal; Ethane-1,2-dione; Ethandial; Aerotex glyoxal 40; ODIX; Protectol GL 40; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; GLYOXAL; 1,2-ETHANEDIONE; ETHANEDIAL; DIFORMYL;Glioksal 40 ; BIFORMYL; OXALDEHYDE; Ethanedial; oxalaldehyde; Glyoxal, 40 % Solution; 83513-30-8; 50NP6JJ975; 1732463; MFCD00006957; 58.03634000; diformal; ethandial; ethane dial; ethane-1,2-dial; ethanedial; ethanedione; 1,2-ethanedione; gelifundol; glyoxal aldehyde; glyoxylaldehyde; oxalaldehyde; oxaldehyde; Glyoxaldehyde; Ethanedial; 1,2-Ethanedione; Diformyl; Ethanedione; Glyoxal aldehyde; 1,2-Ethanedione; Biformyl; Ethanedial; Oxalaldehyde; C2H2O2 / OHCCHO; Molecular mass: 58.0; ICSC # 1162; Glyoxal, 40 wt% solution in water; AC156220000; AC156220010, AC156220025; AC156220050; AC156225000; BP1370-500; Biformal; Diformal; Ethandial; Glyoxylaldehyde; 231-791-2; 203-474-9; 7732-18-5; ZC0110000; 107-22-2;MD2625000; MD2650000; MD2700000; 7-(2-Hydroxyethyl)decahydro-1H,6H-3a,5a,8a,10a-tetraazapyrene; 1435472-42-6 ; Ethanedial; oxalaldehyd; Glyoxal 40dehyde, Ethanedial, 1,2-Ethanedione, Diformyl, Ethanedione, Glyoxal aldehyde; Ethane-1,2-dione; Biformal; Ethanedial; Oxalaldéhyde; Glyoxal 40; Glyoxal 40%; Glyoxal %40; Glioksal 40; Glioksal 40%; Glioksal %40; GLYOXAL 40; GLYOXAL 40%; GLYOXAL %40; GLOKSAL 40; GLOKSAL 40%; GLOKSAL %40; GLIOKSAL 40; GLIOKSAL 40%; GLIOKSAL %40;
Glyoxal 40
Glyoxal 40
Glyoxal 40
Skeletal formula of Glyoxal 40
Space-filling model of glyox
Names
Preferred IUPAC name
Oxaldehyde
Systematic IUPAC name
Ethanedial
Other names of Glyoxal 40 40
Glyoxal 40
Oxalaldehyde
Identifiers of Glyoxal 40
CAS Number of Glyoxal 40
107-22-2 ☑
3D model (JSmol)
Interactive image
ChEBI
CHEBI:34779 ☑
ChemSpider
7572 ☑
ECHA InfoCard 100.003.160
KEGG
C14448 ☑
PubChem CID
7860
UNII
50NP6JJ975 ☑
Properties of Glyoxal 40
Chemical formula of Glyoxal 40
C2H2O2
Molar mass of Glyoxal 40 58.036 g·mol-1
Density of Glyoxal 40 1.27 g/cm3
Melting point of Glyoxal 40 15 °C (59 °F; 288 K)
Boiling point of Glyoxal 40 51 °C (124 °F; 324 K)
Thermochemistry
Heat capacity of Glyoxal 40 (C)
1.044 J/(K·g)
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamond
121
Flash point -4 °C (25 °F; 269 K)
Autoignition
temperature
285 °C (545 °F; 558 K)
Related compounds
Related aldehydes
acetaldehyde
glycolaldehyde
propanedial
methylglyoxal
Related compounds
glyoxylic acid
glycolic acid
oxalic acid
pyruvic acid
diacetyl
acetylacetone
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Glyoxal 40 is an organic compound with the chemical formula OCHCHO. It is the smallest dialdehyde (a compound with two aldehyde groups). It is a crystalline solid, white at low temperatures and yellow near the melting point (15 °C). The liquid is yellow, and the vapor is green.[1]
Pure Glyoxal 40 is not commonly encountered because it forms hydrates, which oligomerize. For many purposes, these hydrated oligomers behave equivalently to Glyoxal 40. Glyoxal 40 is produced industrially as a precursor to many products.[2]
Glyoxal 40% Applications
1.Glyoxal mainly used for glyoxylate, M2D resin, imidazole and other raw materials, products, and as gelatin, gelatin, cheese, alcohol, and insoluble starch adhesives, artificial silk resistance reduction agent.
2.Recently , With the fast development of the application in pharmacy, textiles and daily construction materials, the application of glyoxal can be wider and wider..
3.In medicine, mainly for the special ring imidazole drugs such as metronidazole, dimetridazole, imidazole, etc..
4.In the intermediate area, mainly for glyoxylate, D-hydroxyphenylglycine, allantoin, benzene Enzyme pharynx, berberine;
5.In the textile, the main agent used for finishing clothing, 2D resin, M2D resin;
6.In the paper industry, mainly for sizing, wet strength increased resistance of paper;in polymer chemistry is a very ef fective cross-linking Factor for cross-linking agent;
7.In the construction industry, cement curing agent used to improve the solidification strength, as a contro
Glyoxal 40% Storage
Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature: 2 – 8 °C
External links
Production
Glyoxal 40 was first prepared and named by the German-British chemist Heinrich Debus (1824-1915) by reacting ethanol with nitric acid.[3][4]
Commercial Glyoxal 40 is prepared either by the gas-phase oxidation of ethylene glycol in the presence of a silver or copper catalyst (the Laporte process) or by the liquid-phase oxidation of acetaldehyde with nitric acid.[2]
The first commercial Glyoxal 40 source was in Lamotte, France, started in 1960. The single largest commercial source is BASF in Ludwigshafen, Germany, at around 60,000 tons per year. Other production sites exist also in the US and China. Commercial bulk Glyoxal 40 is made and reported as a 40%-strength solution in water.
Glyoxal 40 may be synthesized in the laboratory by oxidation of acetaldehyde with selenious acid.[5]
Anhydrous Glyoxal 40 is prepared by heating solid Glyoxal 40 hydrate(s) with phosphorus pentoxide and condensing the vapors in a cold trap.[6]
Applications of Glyoxal 40 40
Coated paper and textile finishes use large amounts of Glyoxal 40 as a crosslinker for starch-based formulations. It condenses with urea to afford 4,5-dihydroxy-2-imidazolidinone, which further reacts with formaldehyde to give the bis(hydroxymethyl) derivative dimethylol ethylene urea, which is used for wrinkle-resistant chemical treatments of clothing, i.e. permanent press.
Glyoxal 40 is used as a solubilizer and cross-linking agent in polymer chemistry.
Glyoxal 40 is a valuable building block in organic synthesis, especially in the synthesis of heterocycles such as imidazoles.[8] A convenient form of the reagent for use in the laboratory is its bis(hemiacetal) with ethylene glycol, 1,4-dioxane-2,3-diol. This compound is commercially available.
Glyoxal 40 solutions can also be used as a fixative for histology, that is, a method of preserving cells for examining them under a microscope.
Glyoxal 40 and its derivatives are also used in the chemical probing of RNA structure, as they react with free guanines in RNAs.[9]
Speciation in solution
Hydrated Glyoxal 40 (top) and derived oligomers, called dimers and trimers. The middle and lower species exist as mixtures of isomers.
Glyoxal 40 is supplied typically as a 40% aqueous solution.[2] Like other small aldehydes, Glyoxal 40 forms hydrates. Furthermore, the hydrates condense to give a series of oligomers, some of which remain of uncertain structure. For most applications, the exact nature of the species in solution is inconsequential. At least one hydrate of Glyoxal 40 is sold commercially, Glyoxal 40 trimer dihydrate: [(CHO)2]3(H2O)2 (CAS 4405-13-4). Other Glyoxal 40 equivalents are available, such as the ethylene glycol hemiacetal 1,4-dioxane-trans-2,3-diol (CAS 4845-50-5, m.p. 91-95 °C),
Glyoxal 40 is estimated that, at concentrations less than 1 M, Glyoxal 40 exists predominantly as the monomer or hydrates thereof, i.e., OCHCHO, OCHCH(OH)2, or (HO)2CHCH(OH)2. At concentrations above 1 M, dimers predominate. These dimers are probably dioxolanes, with the formula [(HO)CH]2O2CHCHO.[10] Dimer and trimers precipitate as solids from cold solutions.
Other occurrences
Glyoxal 40 has been observed as a trace gas in the atmosphere, e.g. as an oxidation product of hydrocarbons.[11] Tropospheric concentrations of 0-200 ppt by volume have been reported, in polluted regions up to 1 ppb by volume.
Molecular Weight of Glyoxal 40 58.04
Molecular Formula of Glyoxal40 C2H2O2
Storage RT
Catalogue No GXL999
CAS No. of Glyoxal 40 107-22-2
Backward-integrated production process of Glyoxal 40
Ethylene – Ethylene glycol – Glyoxal 40%
-Textile resins
-Paper resins
-Oilfield
-Imidazoles
Sustainability of Glyoxal 40 :
Glyoxal 40 is readily biodegradable by
showing more than 90% decrease of
dissolved organic carbon according to
OECD guidelines 301 C-E and 303 A.
Accreditation for food packaging:
Glyoxal 40 is listed as an accredited
chemical substance for the production
of paper for food packaging by the
Federal Institute for Risk Assessment
(BfR) in Germany, and by the Food
and Drug Administration (FDA) in the
U.S.
Substitution of aldehydes:
Glyoxal 40 shows high potential in the
substitution of aldehydes, e.g. for
formaldehyde or glutaraldehyde. Additionally, in disinfection it can be used
as a co-biocide formulated together
with glutaraldehyde.
Reliability:
With 60,000 metric tons annual worldscale production in Ludwigshafen
we are a leading player in the Glyoxal 40
industry. Our backward-integrated
production of Glyoxal 40 guarantees
efficient and reliable supply wherever
you are.
Services:
Whether you need bulk or packaged
material, we ensure efficient solutions.
Our advice on packaging and dedicated
storage facilities guarantee reliable
supply to allow you to run your business
steadily.
Application expertise:
we make our expertise available to our partners. Working together
with our customers in successful
partnerships will offer mutual benefits.
Registration support:
Description
General description
The product is 40wt.% solution of Glyoxal 40 in water. Glyoxal 40 is a linear aliphatic dialdehyde containing two aldehyde groups.[1] Glyoxal 40 participates in the synthesis of glyoxylic acid. It is highly reactive in nature. Glyoxal 40can be prepared by oxidizing ethanol or acetaldehyde with nitric acid.Glyoxal 40 is widely employed in textile and paper industry.[2]
Application
Glyoxal 40 solution has been used as a crosslinking agent during the synthesis of DNA-containing nanoparticles in a study.[3] Glyoxal 40 has been used as derivatizing reagent, in the precolumn fluorescence derivatization of N-terminal tryptophan containing peptides which can be separated via high performance liquid chromatography.[4] Glyoxal 40 may also be used in the synthesis of Glyoxal 40 bis(4-phenyl-3-thiosemicarbazones)solution, which can be used in the spectrophotometric determination of palladium in catalysts.[5]
Packaging
1, 3 kg in poly bottle
5 g in glass bottle
100 g in poly bottle
22, 50 kg in poly drum
Other Notes
This form of glyoxal 40 is composed of 3 moles of Glyoxal 40 and 2 moles of water in a relatively stable configuration.
Caution
May precipitate on storage; redissolve at 50-60 °C.
Glyoxal 40 , 40 % Solution is used to denature nucleic acids by forming stable complexes with guanine residues
Glyoxal 40%
Categories: Fluid
Material Notes: Formula: C2H2O2
CAS: 107-22-2
Description: Glyoxal 40 is a colorless to yellow liquid, with a faint odor. Glyoxal 40 is also miscible with water.
Synonyms: Glyoxaldehyde, Ethanedial, 1,2-Ethanedione, Diformyl, Ethanedione, Glyoxal aldehyde
Applications: Intermediate used in the production of Adhesives, Cross linkers, Paper resins, Pharmaceuticals, Sulfur scavenging and Textile resins
Product Description:Glyoxal 40, 40% solution: Glyoxal 40 is a nucleic acid denaturant. It acts as a specific probe for homopurine strands of DNA.
GENERAL DESCRIPTION
Yellow crystals melting at15°C. Hence often encountered as a light yellow liquid with a weak sour odor. Glyoxal 40 is a 2-carbon aldehyde with carbonyl groups on both carbons.Glyoxal 40 is a yellow crystals melting at15°C. Hence often encountered as a light yellow liquid with a weak sour odor. Vapor has a green color and burns with a violet flame.
Combustible. Incompatible with strong oxidizing agents. Strong reducingagent. May polyermize exothermically. Incompatible with air, water, oxygen,peroxides, amides, amines, hydroxy-containing material s, nitric acid, aldehydes. Corrodes many metals.
Mechanism of Action
Glyoxal 40 attacks the amino groups of proteins, nucleotides, and lipids with its highly reactive carbonyl groups. A sequence of non-enzymatic reactions, called glycation, yields stable advanced glycation end-products (AGEs) with a background extent of 0.1-1% of lysine and arginine residues in proteins and 1 in 1.0 X 10-7 nucleotides in DNA. … Glyoxal 40 forms stable adducts with guanosine by reaction with the N-1 as well as with the exocyclic nitrogen of guanine. The rate of Glyoxal 40-guanine adduct formation is rapid under physiological conditions. A stable tricyclic Glyoxal 40-DNA adduct is formed by covalent binding to two nitrogens of guanine under physiological conditions in vitro. Besides 8-hydroxy-deoxyguanosine, the Glyoxal 40-deoxyguanosine (dG) adduct is one of the major deoxyguanosine oxidation products, being formed by oxygen radicals, lipid peroxidation systems, various types of oxidative stress, and UV irradiation and after in vivo exposure to beta-hydroxy-substituted N-nitrosamines.
Glyoxal 40 (O=CH-CH=O) is an α-oxoaldehyde, and it is often grouped with two similar α-oxoaldehydes, methylGlyoxal 40, and 3-deoxyglucosone. All three compounds are products of various metabolic and oxidative reactions and are capable of causing cellular damage and apoptosis. They are also involved in the formation of advanced glycation end-products (AGEs) which have been linked to long-term sequela of chronic diseases such as diabetic retinopathy, neuropathy, and nephropathy. Glyoxal 40 is primarily detoxified by the Glyoxal 40ase system present in the cells of bacteria, protozoa, fungi, plants, animals, and humans. However, it has been suggested that several other enzymes are capable of detoxifying Glyoxal 40, including aldehyde dehydrogenase (ALDH) which can oxidize Glyoxal 40 to glyoxylate.
Glyoxal 40 is considered an important intermediate in the formation of advanced glycation end-products (AGEs). AGE modification alters protein function and inactivates enzymes, resulting in disturbance of cellular metabolism, impaired proteolysis, and inhibition of cell proliferation and protein synthesis. The extent of AGE modification increases with the increasing life span of proteins. Consequently, AGEs are especially associated with long-lived proteins, such as collagens, lens crystallins, and neurofilaments, but also have been identified in shorter-lived proteins, including hemoglobin, plasma proteins, lipoproteins, and intracellular proteins.
Inhibition studies in bacterial mutagenicity tests demonstrated the production of the reactive oxygen species superoxide, hydrogen peroxide, and singlet oxygen from Glyoxal 40. The mutagenic activity of Glyoxal 40 is related to singlet oxygen, as well as to the intracellular GSH level. The hydroxyl radical plays a prominent role in Glyoxal 40-induced DNA cleavage.
Isolated rat hepatocytes were incubated with different concentrations of Glyoxal 40. Glyoxal 40 by itself was cytotoxic at 5mM, depleted GSH, formed reactive oxygen species (ROS) and collapsed the mitochondrial membrane potential. Glyoxal 40 also induced lipid peroxidation and formaldehyde formation. Glycolytic substrates, eg fructose, sorbitol and xylitol inhibited Glyoxal 40-induced cytotoxicity and prevented the decrease in mitochondrial membrane potential suggesting that mitochondrial toxicity contributed to the cytotoxic mechanism. Glyoxal 40 cytotoxicity was prevented by the Glyoxal 40 traps d-penicillamine or aminoguanidine or ROS scavengers were also cytoprotective even when added some time after Glyoxal 40 suggesting that oxidative stress contributed to the Glyoxal 40 cytotoxic mechanism.
The cytosolic GSH-dependent Glyoxal 40ase system is the major pathway for the detoxification of Glyoxal 40 … Glyoxal 40 reacts non-enzymatically with GSH with formation of a hemithioacetal, which is subsequently converted to S-glycolylglutathione by Glyoxal 40ase I. Glyoxal 40ase II catalyses the hydrolysis of S-glycolylglutathione to glycolate, re-forming the GSH from the first reaction. The activity of Glyoxal 40ase I in situ is approximately proportional to the cytosolic concentration of GSH. When GSH is severely depleted (eg, under conditions of oxidative stress), however, 2-oxoaldehyde dehydrogenase and aldose reductase may also metabolize Glyoxal 40. Imbalances in intracellular redox systems may impair these detoxification mechanisms, resulting in higher levels of Glyoxal 40. A further GSH-independent route of detoxification via Glyoxal 40ase III exists.
Use and Manufacturing
Fillers
Intermediates
Odor agents
Processing aids, not otherwise listed
Solids separation agents
Water Treatment Products
Its versatile properties the intermediate Glyoxal 40 is the product of choice for various applications. In textile manufacturing, for example, this efficient crosslinker decreases water uptake in crosslinking cellulose. In oil recovery, Glyoxal 40 crosslinks polymers, thus increasing the viscosity of fracturing fluids.
Glyoxal 40 is also used in the paper, leather and epoxy industries. Beside known applications, Glyoxal 40 shows potential for new applications which are still in the early stages of development.
Glioksal 40
Glioksal 40
Glioksal 40 iskelet formülü
Glioksal 40 boluk doldurma modeli
simler
Tercih edilen IUPAC ad
Oxaldehyde
Sistematik IUPAC ad
etandial
Dier isimler
Glioksal 40
Oxalaldehyde
Glioksal 40 Tanmlayclar
Glioksal 40 CAS numaras
107-22-2 ☑
3D model ( JSmol )
Etkileimli görüntü
Chebi
Glioksal 40 Chebi: 34779 ☑
Glioksal 40 ChemSpider
7572 ☑
Glioksal 40 ECHA Bilgi Kart 100.003.160
Glioksal 40 KEGG
C14448 ☑
Glioksal 40 PubChem CID
7860
Glioksal 40 UNII
50NP6JJ975 ☑
Glioksal 40 CompTox Kontrol Paneli ( EPA )
DTXSID5025364 Bunu Wikidata’da düzenle
InChI[göster]
SMILES[göster]
Glioksal 40 Özellikleri
Glioksal 40 Kimyasal formül
C- 2 , H 2 O 2
Glioksal 40 Molar kütle 58.036 g · mol -1
Glioksal 40 Younluk 1.27 g / cc 3.
Glioksal 40 Erime noktas 15 ° C (288 K)
Glioksal 40 Kaynama noktas 51 ° C (124 ° F; 324 K)
Glioksal 40 Termokimya
Glioksal 40 Is kapasitesi ( C )
1.044 J / (K · g)
Glioksal 40 Tehlikeler
NFPA 704 (ate prlanta)
NFPA 704 dört renkli elmas
121
Glioksal 40 Alevlenme noktas -4 ° C (25 ° F; 269 K)
Kendiliinden tutuma
scakl
285 ° C (545 ° F; 558 K)
Bantl bileikler
lgili aldehitler
asetaldehit
glikolaldehid
propanedial
metilGlioksal 40
Bantl bileikler
glikoksilik asit
glikolik asit
oksalik asit
piruvik asit
diasetil
asetilaseton
Aksi belirtilmedikçe, standart halindeki malzemeler için veriler verilir (25 ° C [77 ° F], 100 kPa’da).
☑ dorula ( nedir ?) ☑☒
Bilgi kutusu referanslar
Glioksal 40 bir bir organik bileik ile kimyasal formül OCHCHO. En küçük dialdehittir (iki aldehit grubuna sahip bir bileik ). Glioksal 40 Kristalli bir katdr, düük scaklklarda beyazdr ve erime noktasna (15 ° C) yakn sardr .Glioksal 40 Sv sar ve buhar yeildir. [1]
Saf Glioksal 40 yaygn olarak görülmez, çünkü oligomerize olan hidratlar oluturur . Birçok amaç için, bu hidratlanm oligomerler, Glioksal 40 ile ayn ekilde davranrlar. Endüstriyel olarak birçok ürünün öncüsü olarak üretilir. [2]
üretim
Glioksal 40 ilk önce etanolü nitrik asit ile reaksiyona sokarak Alman-ngiliz kimyager Heinrich Debus (1824-1915) tarafndan hazrland ve adlandrld . [3] [4]
Ticari Glioksal 40 gaz faz yoluyla hazrlanr oksidasyon ve etilen glikol , bir mevcudiyetinde gümü ya da bakr katalizörü (Laporte ilemi) ya da sv fazl oksidasyonu ile asetaldehid ile nitrik asit . [2]
lk ticari Glioksal 40 kaynak oldu Lamotte tek büyük ticari kaynadr 1960 ylnda balayan, aralarnda Fransa BASF içinde Ludwigshafen , Almanya ylda yaklak 60.000 ton. ABD ve Çin’de baka üretim tesisleri de bulunmaktadr. Ticari dökme Glioksal 40 yaplr ve suda% 40’lk bir mukavemet çözeltisi olarak rapor edilir.
Glioksal 40 , asetaldehitin selenious asit ile oksidasyonu yoluyla laboratuvarda sentezlenebilir . [5]
Susuz Glioksal 40 , kat Glioksal 40 hidrat (lar) fosfor pentoksit ile starak ve buharlar souk bir tuzakta younlatrarak hazrlanr . [6]
Glioksal 40 Uygulamalar
Glioksal 40 Kue kat ve tekstil kaplamalar ,
Glioksal 40 niasta bazl formülasyonlar için çapraz balayc olarak büyük miktarlarda kullanr .
Glioksal 40 Üre ile younlaarak , giysinin krmaya dayankl kimyasal ilemleri, yani kalc pres için kullanlan bis (hidroksimetil) türevi dimetilol etilen üre verecek ekilde formaldehit ile reaksiyona giren 4,5-dihidroksi-2-imidazolidinon elde edilir.
Glioksal 40 , polimer kimyasnda bir çözünürletirici ve çapraz balama maddesi olarak Glioksal 40 kullanlr .
Glioksal 40 organik sentezde , özellikle imidazoller gibi heterosikllerin sentezinde deerli bir yap tadr . [8] Laboratuarda kullanm için uygun bir reaktif formu etilen glikol , 1,4-dioksan-2,3-diol ile bis (hemiasetal) ‘dir . Bu bileik ticari olarak temin edilebilir.
Glioksal 40 çözeltiler ayrca histoloji için bir fiksatif olarak , yani hücreleri mikroskop altnda incelemek için bir koruma yöntemi olarak kullanlabilir.
Glioksal 40 ve türevleri, RNA’lardaki serbest guaninlerle reaksiyona girdikleri için RNA yapsnn kimyasal olarak incelenmesinde de kullanlr . [9]
Çözeltide türleme
Hidratl Glioksal 40 (üstte) ve dimerler ve trimerler olarak adlandrlan türetilmi oligomerler. Orta ve alt türler izomer karmlar olarak bulunur.
Glioksal 40 tipik olarak% 40’lk bir sulu çözelti halinde salanr. [2] Dier küçük aldehitler gibi ,Glioksal 40 da hidratlar oluturur. Ayrca hidratlar, bazlar belirsiz bir yapda kalan bir dizi oligomer vermek üzere younlar. Çou uygulama için, çözeltideki türlerin kesin doas önemsizdir. Glioksal 40 en az bir hidrat, ticari olarak satlmaktadr, Glioksal 40 trimeri dihidrat: [(CHO) 2 ] 3 (H 2 O) 2 (CAS 4405-13-4). Etilen glikol hemiasetal 1,4-dioksan- trans -2,3-diol ( CAS 4845-50-5, en 91-95 ° C) gibi dier Glioksal 40 edeerleri mevcuttur ,
1 M’den düük konsantrasyonlarda , Glioksal 40n arlkl olarak monomer veya hidratlar, yani OCHCHO, OCHCH (OH) 2 veya (HO) 2 CHCH (OH) 2 olduu tahmin edilmektedir . 1 M’nin üzerindeki konsantrasyonlarda dimerler baskndr. Bu dimerler muhtemelen dioksolanlar , formül [(HO) CH] ile, 2 O 2 CHCHO. [10] Dimer ve trimerler souk çözeltilerden katlar halinde çökelir.
Dier olaylar
Glioksal 40 atmosferde bir eser gaz olarak, örnein hidrokarbonlarn bir oksidasyon ürünü olarak gözlenmitir . [11] Hacimce 1 ppb’ye kadar kirli bölgelerde, hacimce 0-200 ppt troposferik konsantrasyonlar bildirilmitir. [12]
Glioksal 40 Ürün açklamas
Glioksal 40% hzl ayrntlar
Kimyasal ad: Glioksal 40% mix
Glioksal 40 CAS No.: 107-22-2
Glioksal 40 EINECS .:203-474-9
Glioksal 40 Moleküler formülü: C2H2O2
Glioksal 40 Kimyasal yaps:Günlük kullanm kimyasallar için glioksal 40%
Glioksal 40 Formülü arlk: 58.04
Glioksal 40 Tahlil: 40% min
Dier isimler: bisformil; glioksilaldehit; Glioksal 40 çözelti;
Glioksal 40; diformil; etanedial; 1,2-etanedion; oksalaldehit
Örnek: mevcut ve ücretsiz.
Uygulamalar özet: tekstil, kat, deri, kozmetik
Glioksal 40% Uygulamalar
1. Glioksal 40 arlkl olarak glioksilat, M2D reçine, imidazol ve dier hammaddeler, ürünler ve jelatin, jelatin, peynir, alkol ve çözünmez niasta yaptrclar, yapay ipek direnci azaltma maddesi olarak kullanlr.
2. Son zamanlarda, eczane, tekstil ve günlük inaat malzemelerinde uygulamann hzl geliimi ile, Glioksal 40 uygulamas daha geni ve daha geni olabilir ..
3. Tpta, özellikle metronidazol, dimetridazole, imidazol vb. Gibi özel halka imidazol ilaçlar için Glioksal 40 kullanlr.
4. Ara alanda, esas olarak glioksilat, d-hidroksifenil glisin, allantoin, benzen enzim farenks, berberin için;
5. Tekstilde, giysiler, 2D reçine, M2D reçine için Glioksal 40 kullanlan ana maddedir;
6.Glioksal 40 Kat endüstrisinde, özellikle boyutlandrma için, slak mukavemet kat direncini arttrr; polimer kimyada çapraz balama maddesi için çok ef fektif çapraz balama faktörüdür;
7. Glioksal 40 Inaat sektöründe, bir contro olarak katlama gücünü artrmak için kullanlan çimento kürleme maddesi
Glioksal 40% Depolama
Kab kuru ve iyi havalandrlm bir yerde skca kapal tutun.
Önerilen depolama scakl: 2-8 °C
GENEL TANIM
Glioksal 40 15 ° C`de eriyen sar kristallerdir. Bu nedenle Glioksal 40 sklkla zayf bir eki kokuya sahip açk sar bir sv olarak karlalr. Glioksal 40, Buharn yeil bir rengi vardr ve mor bir alevle yanar. Glioksal 40, Yancdr.Glioksal 40 Güçlü oksitleyici ajanlarla uyumaz. Glioksal 40, Güçlü indirgeyicidir. Glioksal 40 Egzotermik olarak polimerize olabilir. Glioksal 40 Hava, su, oksijen, peroksitler, amidler, aminler, hidroksi içeren maddeler, nitrik asit, aldehitlerle uyumaz. Glioksal 40, Birçok metali korozif hale getirir.
HAREKET MEKANZMASI
Glioksal 40, proteinleri, nükleotidleri ve lipidlerin amino gruplarna yüksek oranda reaktif karbonil gruplaryla saldrr. Glikasyon denilen enzimatik olmayan reaksiyonlardan oluan bir dizi, DNA`da linyin ve arginin artklarn ve DNA`da 1.0 x 10-7 nükleotidde 1`lik bir arka plan kapsam ile kararl ilerlemi glikasyon son ürünler (AGE`ler) üretir. … Glyoksal, Guanin`in ekzosiklik azotunun yan sra N-1 ile reaksiyona girerek guanozin ile kararl adüktler oluturur. Glioksal-guanin adükt oluumu fizyolojik koullar altnda hzldr. Stabil bir trisiklik glioksal-DNA adüktü, in vitro fizyolojik koullar altnda iki guanin azotuna kovalent balanma yoluyla oluur. 8-hidroksi-deoksiguanozin yan sra, glioksal-deoksiguanozin (dG) adükt, oksijen radikalleri, lipit peroksidasyon sistemleri, çeitli oksidatif stres tipleri ve UV nlamas ile ve in vivo beta maruziyetinden sonra olumakta olan önemli deoksiguanozin oksidasyon ürünlerinden biridir -hidroksi-ikameli N-nitrosaminler.
Glioksal 40, gelimi glikasyon son ürünler (AGE`ler) oluumunda önemli bir ara ürün olarak düünülür. AGE modifikasyonu protein fonksiyonunu deitirir ve enzimleri inaktive eder, bu da hücresel metabolizma bozukluuna, bozulmu proteolize ve hücre proliferasyonunun ve protein sentezinin inhibisyonuna neden olur. AGE modifikasyonunun derecesi, proteinlerin ömrünün uzamasna bal olarak artmaktadr. Sonuç olarak, AGE`ler özellikle kollajen, mercek kristalinleri ve nörofilamentler gibi uzun ömürlü proteinlerle ilikilidir ancak ayn zamanda hemoglobin, plazma proteinleri, lipoproteinler ve hücre içi proteinler de dahil olmak üzere daha ksa süren proteinlerde tanmlanmtr.
Bakteriyel mutajenite testlerinde yaplan inhibisyon çalmalar, glioksaldan süperoksit, hidrojen peroksit ve singlet oksijen üretildiini göstermitir. Glioksaln mutajenik aktivitesi, singlet oksijene ve hücre içi GSH seviyesine ilikindir. Hidroksil radikali glioksal kaynakl DNA bölünmesinde belirgin bir rol oynamaktadr.
zole edilmi sçan hepatositleri farkl glkoksal konsantrasyonlar ile inkübe edildi. Glioksal 40 tek bana 5 mM`de sitotoksik, tükenmi GSH, reaktif oksijen türleri (ROS) oluturdu ve mitokondriyal membran potansiyelini çökertti. Glyoksal ayn zamanda lipit peroksidasyonu ve formaldehit oluumuna neden olmutur. Glikolitik substratlar, örnein fruktoz, sorbitol ve ksilitol glioksal kaynakl sitotoksisiteyi inhibe etti ve mitokondriyal membran potansiyelindeki azalmay önledi, mitokondriyal toksisitenin sitotoksik mekanizmaya katkda bulunduunu düündürdü. Glioksal sitotoksisite, glioksal tuzaklar d-penisilamin veya aminoguanidin ile engellendi veya ROS atclar, glioksal sonras bir süre ilave edildiklerinde bile sitoprotektifti; oksidatif stresin glioksal sitotoksik mekanizmaya katkda bulunduunu düündürdü.
Sitozolik GSH`ye bal glioksalaz sistemi, glioksaln detoksifikasyonunun balca yoludur. Glioksal 40, gliokzalaz I ile daha sonra S-glikolglutatiyona dönütürülen bir hemitiyoasetal oluumu ile enzimatik olmayan ekilde GSH ile tepkimeye girer. Glikozalaz II, hidrolizini katalize eder S-glikolglutatyonun glikolata dönütürülmesi, ilk reaksiyondan GSH`nin yeniden oluturulmas. Gloksalaz I in in situ aktivitesi, GSH`nin sitozolik konsantrasyonu ile yaklak olarak orantldr. GSH iddetle tükendiinde (örnein, oksidatif stres koullar altnda), 2-oksoaldehid dehidrojenaz ve aldoz redüktaz da glioksal metabolize edebilir. Hücre içi redoks sistemindeki dengesizlikler bu detoksifikasyon mekanizmalarn bozabilir ve bu da glioksal düzeyinin yükselmesine neden olabilir. Glyokzalaz III yoluyla GSH`den bamsz bir baka detoksifikasyon yolu mevcuttur.
KULLANIM VE MALAT
Dolgu
Ara ürünler
Koku maddeleri
leme yardmclar
Kat ayrma maddeleri
Su Artma Ürünleri
Çok yönlü özellikleri ara Glioksal 40, çeitli uygulamalar için tercih edilen üründür. Örnein, tekstil imalatnda, bu verimli çapraz balayc, çapraz balayc selülozdaki su alm miktarn düürür. Glioksal 40 Ya geri kazanmnda, glioksal, polimerleri çapraz balar ve böylece krk akkanlarn viskozitesini arttrr.
Glioksal 40 kat, deri ve epoksi endüstrilerinde de kullanlr. Bilinen uygulamalarn yannda, glioksal, geliimin erken evrelerinde olan yeni uygulamalar için potansiyel göstermektedir. laçlarn, yaptrclar ve kaplayclarn, tekstil reçinelerinin ve tekstil reaktan ürünlerin üretiminde, kat reçinelerinin üretiminde ve of set-özel kaplama banyolarnda kullanlr. Çapraz balayclarn üretiminde ara madde olarak kullanlr. Örnein; kopolimerlerin üretimi, boya ara maddeleri, ilaçlar, mahsül (ürün) koruma ajanlar, böcek ilaçlar, kat, tekstil ve deri yardmclar, korozyon önleyiciler ve fotoraf kimyasallar için kullanlr. Organik sentezlerde (tbbi ürünler, boya maddeleri vs…), ev ve hastane dezenfeksiyonu biositlerinde, çeitli muhteliflerin kullanm, çeitli doldurucularn ynlanmas ve mineral doldurucu muamelesinde, selüloz eterlerinin yumrulama kart ilenmesinde ve hava koku giderici ajanlarda kullanlr. Ayrca hidrokolloidlerin üretimi, epoksi ve fenolik reçinelerin üretiminde ve tütün katks olarak da kullanlmaktadr.
Glyoxal 40
Glyoxal 40 en solution aqueuse pour la synthèse
Formule: C₂H₂O₂
Poids moléculaire: 58,04 g/mol
Densité: 1,27 g/cm³ (20 °C)
Température de stockage: Température ambiante
Numéro MDL: MFCD00006957
Numéro CAS: 107-22-2
EINECS: 203-474-9
UN: 0000
Éthanedial
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Éthanedial
Glyoxal-2D-skeletal.svg Glyoxal 40-3D-vdW.png
Identification
Nom UICPA éthanedial
Synonymes
éthane-1,2-dione, glyoxal
No CAS 107-22-2
No ECHA 100.003.160
SMILES
[Afficher]
InChI
[Afficher]
Apparence liquide, prisme jaune sous 15 °C
Propriétés chimiques
Formule brute C2H2O2 [Isomères]
Masse molaire1 58,0361 ± 0,0023 g/mol
C 41,39 %, H 3,47 %, O 55,14 %,
Propriétés physiques
T° fusion 15 °C2
T° ébullition 50,4 °C2,3
Solubilité 600 g·l-1 dans l’eau à 20 °C2
Masse volumique 1,14 g·cm-32
Pression de vapeur saturante 293 mbar à 20 °C 2
Unités du SI et CNTP, sauf indication contraire.
modifier Consultez la documentation du modèle
L’éthanedial ou Glyoxal 40 est un composé organique de formule brute C2H2O2 et de formule semi-développé O=CH-CH=O. Ce liquide de couleur jaune est le plus petit dialdéhyde existant. C’est aussi une forme tautomère de l’éthynediol (HO-C≡C-OH) .
Sommaire
1 Production et synthèse
2 Utilisation
3 Solution d’éthanedial
4 Autre origine
5 Références
6 Lien externe
Production et synthèse
L’éthanedial commercial est préparé soit par l’oxydation en phase gazeuse de l’éthylène glycol (éthane-1,2-diol), catalysée par de l’argent voire du cuivre, soit par l’oxydation en phase liquide d’éthanal en présence d’acide nitrique. La capacité globale de production est d’environ 220 000 tonnes par an avec une baisse de production due à une surcapacité asiatique. La plupart de la production se fait en phase gazeuse. Le premier producteur d’éthanedial était situé sur le site de Lamotte à Trosly-Breuil en France, site dont le propriétaire actuel est Weylchem. Aujourd’hui la production est largement dominée par BASF en Allemagne, sur le site de Ludwigshafen. Ils atteignent 60 000 tonnes par an. Il existe seulement deux sites de production en Amérique (Geismer en Californie et Charlotte en Caroline du nord). Récemment, la Chine s’est dotée de capacités de production supplémentaires.
Au laboratoire, l’éthanedial est synthétisé par oxydation de l’éthanal avec de l’acide sélénique4. La préparation de l’éthanedial anhydre se fait par chauffage d’hydrates de ce composé avec du pentoxyde de phosphore dans un dispositif doté d’un recondenseur5.
Utilisation
Les industries du papier et du textile utilisent de grandes quantités d’éthanedial qui joue le rôle d’agent de réticulation pour des formulations à partir d’amidon. C’est également un initiateur des urées utilisées lors de traitements chimiques augmentant la résistance aux froissements. L’éthanedial sert d’agent de solubilisation et d’agent de réticulation en chimie des polymères:
protéines (tannage du cuir)
collagène
dérivés cellulosiques (textiles)
hydrocolloides
amidon
c’est un bon intermédiaire en chimie organique, particulièrement pour la synthèse d’hétérocycles comme les imidazoles6. Une forme du réactif utilisée en laboratoire est le bis-hemiacétal avec de l’éthylène glycol, 1,4-dioxane-2,3-diol. Ce composé est disponible dans le commerce.
Solution d’éthanedial
Le composé est fourni typiquement en solution aqueuse concentrée à 40 %. Comme d’autres petits aldéhydes, il forme des hydrates. De plus ces hydrates se condensent pour former une série d’oligomères, dont la structure reste mal connue. Pour la plupart des applications, la structure exacte n’a pas de conséquences. Au moins deux hydrates d’éthanedial sont vendus dans le commerce:
un dimère d’éthanedial, dihydraté: [(CHO)2]2[H2O]2, 1,4-dioxane-trans-2,3-diol (CAS# 4845-50-5, p.f. 91 à 95 °C)
un trimère d’éthanedial, dihydraté:: [(CHO)2]3(H2O)2 (CAS# 4405-13-4).
On estime qu’à des concentrations inférieures à 1 mol/L, l’éthanedial existe majoritairement sous forme de monomère, c’est-à-dire: OCHCHO, OCHCH(OH)2, ou (HO)2CHCH(OH)2. À des concentrations supérieures à 1 mol/L, la forme prédominante est le dimère. Ces dimères sont probablement des dioxanes, de formules [(HO)CH]2O2CHCHO7. Les dimères et les trimères peuvent précipiter en raison d’une solubilité plus faible dans des solutions plus froides, à moins de 4,4 °C.
Autre origine
L’éthanedial est un composé inflammable formé lorsqu’on chauffe des mélanges d’huiles et de lipides à haute température.
Information Technique
Formulation :40% w/w aq. soln
État Physique :Liquid
Solubilité :Soluble in water (1000 mg/ml), DMSO, and methanol.
STOCKAGE :Store at 4° C
Point de fusion :-14° C
Point d’Ébullition :104° C
Densité :1.27 g/mL at 20° C
Indice de Réfraction :n20D 1.41
Description de Glyoxal 40%:
Glyoxal 40%
Solution d’eau glyoxal 40%
Glyoxal 40 est l’aldéhyde doux le plus simple, la formule moléculaire est OHCCHO et le poids moléculaire est 58, le monomère Glyoxal 40 pur est achromatique ou jaune clair ou liquide, avec une proportion (d20 ° C) 1,26, points de fusion 15 ° C, point d’ébullition 50,5 ° C et indice de réfraction 1,3826. La vapeur de Glyoxal 40 est verte, en brûlant, elle envoie une flamme pourpre. Le Glyoxal 40 industriel peut se dissoudre dans l’eau, l’éther et l’ethaol. Le Glyoxal 40 industriel existe habituellement dans une solution aqueuse d’environ 40% d’eau. Outre la nature réactionnelle de tout l’aldéhyde, le Glyoxal 40 a une propriété chimique spéciale pour ses deux groupes fonctionnels de coordonnées.
La réaction de la solution aqueuse de Glyoxal 40 est identique à celle du Glyoxal 40 moléculaire unique. Les réactions majoritaires sont des réactions de substitution auxquelles se produisent deux atomes d’hydroxyle. Le Glyoxal 40 réagit avec le composé au centre du nucléophile individuel, et produit des molécules de type ligne. Le Glyoxal 40 réagit avec le composé au centre des deux nucléophiles stables et entraîne des réactions de cyclocompounds, mais prépare de nombreux produits chimiques fins, la médecine et les intermédiaires de la médecine.
Application
1. Glyoxal 40 principalement utilisé pour le glyoxylate, la résine M2D, l’imidazole et d’autres matières premières, des produits, et comme la gélatine, la gélatine, le fromage, l’alcool et les adhésifs d’amidon insoluble, agent de réduction de la résistance artificielle de soie.
2. Récemment, avec le développement rapide de l’application en pharmacie, les textiles et les matériaux de construction quotidiens, l’application de Glyoxal 40 peut être plus large et plus large.
3. En médecine, principalement pour les médicaments anidazole en anneau spéciaux tels que le métronidazole, le dimetridazole, l’imidazole, etc.
4. dans la zone intermédiaire, principalement pour le glyoxylate, la D-hydroxyphénylglycine, l’allantoïne, le benzène, l’Enzyme pharynx, la berbérine;
5. Dans le textile, le principal agent utilisé pour la finition des vêtements, résine 2D, M2D résine;
6. Dans l’industrie papetière, principalement pour le calibrage, la résistance à l’état humide augmente la résistance du papier, dans la chimie des polymères est un facteur de réticulation très ef fi cace pour l’agent de réticulation;
7. dans l’industrie de la construction, l’agent de durcissement de ciment utilisé pour améliorer la force de solidification, comme un glissement de terrain de contrôle, peut empêcher la perte de boue pour empêcher l’effondrement.
Glyoxal 40 40
Solution permettant de déterminer les réductones dans le vin.
La détermination du SO2 libre ne tient pas compte des réductones dans les vins. Les réductones sont des substances auxquelles le sulfite se lie, comme les polyphénols (principalement le tanin), l’acétaldéhyde et l’acide ascorbique (vitamine C). En moyenne, on table respectivement sur 5 mg/l, 10 mg/l et 30 mg/l de réductones dans le vin, pour les vins blancs, rosés et rouges. On calcule ensuite le SO2 libre (mg/l) en retranchant du SO2 mesuré 5, 10 ou 30 mg/l de réductones. Attention, il s’agit d’une quantité estimée.
Pour déterminer la quantité réelle, l’utilisation du Glyoxal 40 est nécessaire. Ce produit permet de se faire une idée plus précise de la quantité de réductones dans le vin, exprimée en mg/l.
EXPOSITION, EFFETS SUR LA SANTE
Voies d’exposition
La substance peut être absorbée dans l’organisme par inhalation de ses aérosols ou de vapeurs et par ingestion.
Effets liés à une exposition de courte durée
La substance est irritante pour les yeux et la peau.
Risque inhalatoire
Une contamination dangereuse de l’air peut être atteinte très rapidement par évaporation de cette substance à 20 °C .
Effets liés à une exposition prolongée ou répétée
Le contact répété ou prolongé peut provoquer une sensibilisation cutanée.
Utilisations
Propriétés physiques
Nom Substance Détails
Glyoxal 40 anhydre
Formule C H O
N° CAS 107-22-2
Etat Physique Liquide
Masse molaire 58,04
Point de fusion 15 °C
Point d’ébullition 50,4 °C (avec dégagement de vapeurs verdâtres, odeur âcre)
Densité 1,14
Densité gaz / vapeur 2
Pression de vapeur 29 kPa à 20 °C
Point d’éclair –
Température d’auto-inflammation –
Glyoxal 40 en solution aqueuse
0 40 % en poids
Formule
N° CAS
Etat Physique Liquide
Masse molaire –
Point de fusion – 14 °C
Point d’ébullition 104 °C
Densité 1,27
Densité gaz / vapeur –
Pression de vapeur 2,4 kPa à 20 °C
Point d’éclair > 100 °C
Température d’auto-inflammation 285 °C
Propriétés chimiques
[1, 2]
Agent de réticulation dans l’industrie du papier, des peintures, colles et adhésifs.
Intermédiaire de synthèse pour la fabrication de produits pharmaceutiques, parfums, colorants, agents de réticulation pour l’industrie textile et divers produits
chimiques.
Désodorisant dans les industries pétrolière et gazière.
Biocide : Le Glyoxal 40 est utilisé comme substance active en tant que produit biocide dans les catégories désinfectants (type de produits (TP) 2 à 4) selon le règlement
528/212/UE.
Une évaluation du Glyoxal 40 est en cours au niveau européen pour les seuls usages cités ci-dessus (France rapporteur). L’utilisation de ces produits biocides est
soumise aux obligations prévues pendant cette période transitoire (cf. partie « Réglementation »).
[1 à 4]
Le Glyoxal 40 anhydre
Il se présente sous la forme d’un liquide jaune pâle ou de cristaux prismatiques, plus ou moins réguliers, jaunes, devenant blancs au refroidissement. La forme
anhydre n’est pas utilisée dans l’industrie.
Très hygroscopique, il se transforme rapidement sous l’action de l’humidité en hydrate de Glyoxal 40 (ou tétrahydroxyéthane), puis en oligomères de celui-ci.
Il est très soluble dans l’eau (600 g/L) ; la dissolution du Glyoxal 40 anhydre s’accompagne d’une polymérisation rapide et exothermique ; cette réaction peut être
violente. Il est également soluble dans de nombreux solvants organiques anhydres.
Le Glyoxal 40 en solution aqueuse
Dans l’industrie, le Glyoxal 40 est essentiellement livré et utilisé sous forme de solutions aqueuses (la plupart du temps à 40 % en poids). Ces solutions, incolores ou jaune
pâle, d’odeur aigre légère, ont un caractère acide (pH = environ 2) et les propriétés suivantes (pour une solution à 40 % en poids).
Le Glyoxal 40 à l’état solide
Le Glyoxal 40 est parfois commercialisé sous forme de cristaux de dihydrate (tétrahydroxyéthane et oligomères), très hygroscopiques, solubles dans l’eau.
Le Glyoxal 40 est un composé très réactif. Il peut réagir violemment avec les oxydants, les acides et les bases fortes. Le contact du produit anhydre avec l’eau entraîne
une polymérisation rapide et exothermique.
En solution aqueuse, le Glyoxal 40 hydraté forme divers oligomères dont l’équilibre dépend du pH, de la température et de la concentration. Dans les conditions
normales d’emploi, les solutions aqueuses sont stables.
Les solutions ont un caractère corrosif vis-à-vis de certains métaux : acier ordinaire, cuivre, aluminium.
Le stockage du Glyoxal 40 et de ses solutions peut s’effectuer dans des récipients en acier inoxydable ou en matières plastiques (polyester et polymères fluorés tels que
polytétrafluoroéthylène).
Le verre est également utilisable pour de petites quantités : dans ce cas, les bonbonnes seront protégées par une enveloppe métallique plus résistante,
convenablement ajustée