TRITON X-100
TRITON X-100
Synonyms:
TRITON X-100; TRTON X-100; TritonTM-X ; Triton X-100; 2315-67-5; Octoxynol-1; Octoxinol; 9002-93-1; Octoxynol; Octoxynol-3; Triton X; Preceptin; Triton x-45; Triton X 45; Octoxynol-9; Hydrol SW; Triton X 100; Triton X 305; Alfenol 3; Alfenol 9; Marlophen 820; Neutronyx 605; Octoxinolum; Poletoxol; Conco nix-100; Hyonic pe-250; Triton X 35; Antarox A-200; Ortho-gynol; Igepal CA-630; Triton X 165; Triton X 405; Triton X 705; Triton X-102; Octoxynol-11; Octoxynol-12; Octoxynol-25; Octoxynol-33; Octoxynol-40; Peg 4-isooctylphenyl ether; PEG-9 Octyl phenyl ether; 4-tert-Octylphenyl peg ether; Peg 4-tert-octylphenyl ether; Texofor FP 300; Triton X 101; Triton X 102; Ethanol, 2-[4-(1,1,3,3 tetramethylbutyl) phenoxy]-; OPE 30; 4-tert-Octylphenol; Monoethoxylate; Polyoxyethylene octyl phenyl ether; Octoxinolum [INN-Latin]; Octoxynol 1;TRITON X-100; TRTON X-100; TRTONTM-X ; TRTON X-100; 2315-67-5; OCTOXYNOL-1; OCTOXNOL; 9002-93-1; OCTOXYNOL; OCTOXYNOL-3; TRTON X; PRECEPTN; TRTON X-45; TRTON X 45; OCTOXYNOL-9; HYDROL SW; TRTON X 100; TRTON X 305; ALFENOL 3; ALFENOL 9; MARLOPHEN 820; NEUTRONYX 605; OCTOXNOLUM; POLETOXOL; CONCO NX-100; HYONC PE-250; TRTON X 35; ANTAROX A-200; ORTHO-GYNOL; IGEPAL CA-630; TRTON X 165; TRTON X 405; TRTON X 705; TRTON X-102; OCTOXYNOL-11; OCTOXYNOL-12; OCTOXYNOL-25; OCTOXYNOL-33; OCTOXYNOL-40; PEG 4-SOOCTYLPHENYL ETHER; PEG-9 OCTYL PHENYL ETHER; 4-TERT-OCTYLPHENYL PEG ETHER; PEG 4-TERT-OCTYLPHENYL ETHER; TEXOFOR FP 300; TRTON X 101; TRTON X 102; ETHANOL, 2-[4-(1,1,3,3 TETRAMETHYLBUTYL) PHENOXY]-; OPE 30; 4-TERT-OCTYLPHENOL; MONOETHOXYLATE; POLYOXYETHYLENE OCTYL PHENYL ETHER; OCTOXNOLUM [INN-LATN]; OCTOXYNOL 1; POLY(OXYETHYLENE)-P-TERT-OCTYLPHENYL ETHER; TRITON X-100; TRTON X-100; TRITON X 100; TRTON X 100; TRITON X-100; TRTON X-100; tritonTM-x ; triton x-100; 2315-67-5; octoxynol-1; octoxinol; 9002-93-1; octoxynol; octoxynol-3; triton x; preceptin; triton x-45; triton x 45; octoxynol-9; hydrol sw; triton x 100; triton x 305; alfenol 3; alfenol 9; marlophen 820; neutronyx 605; octoxinolum; poletoxol; conco nix-100; hyonic pe-250; triton x 35; antarox a-200; ortho-gynol; gepal ca-630; triton x 165; triton x 405; triton x 705; triton x-102; octoxynol-11; octoxynol-12; octoxynol-25; octoxynol-33; octoxynol-40; peg 4-isooctylphenyl ether; peg-9 octyl phenyl ether; 4-tert-octylphenyl peg ether; peg 4-tert-octylphenyl ether; texofor fp 300; triton x 101; triton x 102; ethanol, 2-[4-(1,1,3,3 tetramethylbutyl) phenoxy]-; ope 30; 4-tert-octylphenol; monoethoxylate; polyoxyethylene octyl phenyl ether; octoxinolum [nn-latin]; octoxynol 1; poly(oxyethylene)-p-tert-octylphenyl ether; trton x-100; triton x-100; trton x 100; triton x 100; TRITON X-100; TRTON X-100; TritonTM-X ; Triton X-100; 2315-67-5; Octoxynol-1; Octoxinol; 9002-93-1; Octoxynol; Octoxynol-3; Triton X; Preceptin; Triton X-45; Triton X 45; Octoxynol-9; Hydrol SW; Triton X 100; Triton X 305; Alfenol 3; Alfenol 9; Marlophen 820; Neutronyx 605; Octoxinolum; Poletoxol; Conco Nix-100; Hyonic Pe-250; Triton X 35; Antarox A-200; Ortho-Gynol; Igepal CA-630; Triton X 165; Triton X 405; Triton X 705; Triton X-102; Octoxynol-11; Octoxynol-12; Octoxynol-25; Octoxynol-33; Octoxynol-40; Peg 4-sooctylphenyl Ether; PEG-9 Octyl Phenyl Ether; 4-Tert-Octylphenyl Peg Ether; Peg 4-Tert-Octylphenyl Ether; Texofor FP 300; Triton X 101; Triton X 102; Ethanol, 2-[4-(1,1,3,3 Tetramethylbutyl) Phenoxy]-; OPE 30; 4-Tert-Octylphenol; Monoethoxylate; Polyoxyethylene Octyl Phenyl Ether; Octoxinolum [INN-Latin]; Octoxynol 1; Poly(Oxyethylene)-P-Tert-Octylphenyl Ether; TRITON X-100; TRTON X-100; TRITON X 100; TRTON X 100; Poly(oxyethylene)-p-tert-octylphenyl ether; TRITON X-100; TRTON X-100; TRITON X 100; TRTON X 100
TRTON X-100
Triton X-100
Triton X-100
Triton X-100.png
Names
IUPAC name
2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethanol
Other names
Polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether
Octyl phenol ethoxylate
Polyoxyethylene octyl phenyl ether
4-Octylphenol polyethoxylate
Mono 30
TX-100
t-Octylphenoxypolyethoxyethanol
Octoxynol-9
Identifiers of Triton X-100
CAS Number of Triton X-100
9002-93-1 ☑
3D model (JSmol)
Interactive image
ECHA InfoCard 100.123.919
PubChem CID of Triton X-100
5590
CompTox Dashboard (EPA)
DTXSID8034085 Edit this at Wikidata
InChI[show] of Triton X-100
SMILES[show] of Triton X-100
Properties of Triton X-100
Chemical formula of Triton X-100 C
14H
22O(C
2H
4O)n (n = 9-10)
Molar mass of Triton X-100 647 g mol-1
Appearance of Triton X-100 viscous colourless liquid
Density of Triton X-100 1.07 g/cm3
Melting point of Triton X-100 6 °C (43 °F; 279 K)
Boiling point of Triton X-100 270 °C (518 °F; 543 K)
Solubility of Triton X-100 in water Soluble
Surface tension of Triton X-100:
CMC of Triton X-100 0.22 mM [1]
Vapor pressure of Triton X-100 < 1 mmHg (130 Pa) at 20 °C
Refractive index (nD) 1.490-1.494[2]
Hazards
Safety data sheet MSDS
Flash point of Triton X-100 251 °C (484 °F; 524 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☑ verify (what is ☑☒ ?)
Infobox references
Triton X-100 (C
14H
22O(C
2H
4O)n) is a nonionic surfactant that has a hydrophilic polyethylene oxide chain (on average it has 9.5 ethylene oxide units) and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. Triton X-100 is closely related to IGEPAL CA-630 or former Nonidet P-40, which might differ from it mainly in having slightly shorter ethylene oxide chains. Thus Triton X-100 is slightly more hydrophilic than Igepal CA-630; these two detergents may not be considered to be functionally interchangeable for most applications.[3] Triton X-100 was originally a registered trademark of Rohm & Haas Co. It was subsequently purchased by Union Carbide and then acquired by Dow Chemical Company upon the acquisition of Union Carbide. Soon afterward (in 2009), Dow also acquired Rohm & Haas Co. Other trademarks for very similar compounds include Conco NI, Dowfax 9N, Igepal CO, Makon, Neutronyx 600’s, Nonipol NO, Plytergent B, Renex 600’s, Solar NO, Sterox, Serfonic N, T-DET-N, Tergitol NP, Triton N, etc.[4]
Triton X detergents are distantly related to Pluronic range of detergents marketed by BASF. The pluronics are triblock copolymers of ethylene oxide and propylene oxide with the ethylene oxide segments being more hydrophilic than the propylene oxide.
Physical properties of Triton X-100
Undiluted Triton X-100 is a clear viscous fluid (less viscous than undiluted glycerol) owing to the hydrogen bonding of its hydrophilic polyethylene oxide parts. Undiluted Triton X-100 has a viscosity of about 270 centipoise at 25 °C which comes down to about 80 centipoise at 50 °C. Triton X-100 is soluble at 25 °C in water, toluene, xylene, trichloroethylene, ethylene glycol, ethyl ether, ethyl alcohol, isopropyl alcohol, and ethylene dichloride. Triton X-100 is insoluble in kerosene, mineral spirits, and naphtha, unless a coupling agent like oleic acid is used.[5]
Uses
Triton X-100 is a commonly used detergent in laboratories.[6] Triton X-100 is widely used to lyse cells to extract protein or organelles, or to permeabilize the membranes of living cells.[7]
Some applications include:
Inactivation of lipid-enveloped viruses (e.g. HIV, HBV, HCV) in manufacturing of biopharmaceuticals
Industrial purpose (plating of metal)
Ingredient in influenza vaccines, including Fluzone
Permeabilizing unfixed (or lightly fixed) eukaryotic cell membranes[7]
Solubilizing membrane proteins in their native state in conjunction with zwitterionic detergents such as CHAPS
Part of the lysis buffer (usually in a 5% solution in alkaline lysis buffer) in DNA extraction
Reducing surface tension of aqueous solutions during immunostaining (usually at a concentration of 0.1-0.5% in TBS or PBS Buffer)
Dispersion of carbon materials for soft composite materials
Restricting colony expansion in Aspergillus nidulans in microbiology
Decellularization of animal-derived tissues
Removing SDS from SDS-PAGE gels prior to renaturing the proteins within the gel
Disruption of cell monolayers as a positive control for TEER measurements
Micellar catalyst
Apart from laboratory use, Triton X-100 can be found in several types of cleaning compounds,[8] ranging from heavy-duty industrial products to gentle detergents. It is also a popular ingredient in homemade vinyl record cleaning fluids together with distilled water and isopropyl alcohol.[9]
Triton X-100 inclusion in the Authorisation List (Annex XIV) of REACH
In December 2012, the European Chemicals Agency (ECHA) included the substance group “4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated” – which includes Triton X-100 – in the Candidate List of substances of very high concern[10] of the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) Regulation which addresses the production, import and use of chemical substances and their potential impacts on human health and the environment.[11] A Triton X-100 degradation product has indeed turned out to be ecotoxic as it possesses hormone-like (estrogeno-mimetic) activity that may act on wildlife.[12] The ECHA finally included the substance group in the Authorisation List (Annex XIV),[13] mandating the pharmaceutical and other industries to replace this detergent by the “sunset date” January 4, 2021, thereby affecting EU manufacturers, importers, and downstream users, as well as non-European manufacturers exporting their products into the EU.
Alternatives for viral inactivation
Since the inclusion of Triton X-100 in the candidate list of substances of very high concern for authorization, pharmaceutical companies, as well as bioprocessing research groups, are in need of an alternative detergent which must at the same time be eco-friendly and effective. Ideally, a Triton X-100 replacement should generate minimal manufacturing process change, because only then the necessary updates of regulatory filings for medicines could be realized without additional animal experiments or even clinical studies. Therefore, an alternative virus-inactivating detergent should have physico-chemical properties similar to Triton X-100, should be soluble, easy to remove, eco-friendly, but not degrade to toxic metabolites. In a recent study,[14] two alternatives for antiviral treatment in biopharmaceutical manufacturing have been identified: Triton X-100 reduced, as well as a novel compound which was named Nereid (after the mermaids in Greek mythology). As reflected by the name, Nereid can be seen as just another relative of the Triton X-100 family, however, due to a small molecular difference, it does not degrade into phenolic compounds the way that Triton X-100 does. The virus inactivation studies comprised experiments with several relevant viruses under various conditions. It turned out that at room temperature, where most virus inactivation steps in biopharmaceutical manufacturing are conducted, both Triton X-100 reduced and Nereid showed similar virus inactivating performances as Triton X-100. In contrast, for some processes that are conducted at cold temperatures, Nereid and Triton X-100 gave better results than Triton X-100 reduced. To date, Nereid can be produced at kilogram-scale using a three-step synthesis, and a patent has been applied for.[15] Nereid is scalable and compatible with existing processes and has not shown any impact on product activity so far. In terms of performance, Nereid would be a robust “all-in-one” replacement for Triton X-100. Thus, it is currently tested in ecotoxicology and biodegradation studies to confirm that it is environmentally safe.
Properties
Related Categories Antigen-Vaccine Preparation, Biochemicals and Reagents, Cell Biology, Cell Culture, Cell Lysis Reagents,
Cell Signaling and Neuroscience, Core Bioreagents, Detergents, Detergents N to Z, Detergents by Applications, Diagnostic Applications, Electrophoresis Chromatography, Enzymology, Life Science Reagents for Immunohistochemistry (IHC), Membrane Protein Solubilization, Non-Ionic Detergents, Research Essentials, Signal Transduction Research Tools, Tissue Processing
Less…
Quality Level 200
grade laboratory grade
description non-ionic
form liquid
mol wt micellar avg mol wt 80,000
average mol wt 625
aggregation number 100-155
Show More (16)
Description
General description
Triton X-100 has hemolytic property[6] and is used for DNA extraction.[4]
Triton X-100 is a common non-ionic surfactant and emulsifier which is often used in biochemical applications to solubilize proteins. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It is utilized for lysing cells to extract protein and cellular organelles. It can also permeabilize the living cell membrane for transfection.[1][5]
Application
Triton X-100 has been used:
• In the permeabilization of cells for immunofluorescence staining
• As a component of lysis buffer in western blot analysis
• As a component of Tris-buffered saline for the preparation of cell sections in Immunogold labelling for electron microscope
Packaging
1 L in poly bottle
100, 500 mL in poly bottle
5 gal in poly drum
1 gal in poly bottle
5 mL in glass bottle
Biochem/physiol Actions
Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.
Triton X-100
Triton X-100
Triton X-100.png
simler
IUPAC ad
2- [4- (2,4,4-trimetilpentan-2-il) fenoksi] etanol
Dier isimler
Polietilen glikol p – (1,1,3,3-tetrametilbutil) -fenil eter
Oktil fenol etoksilat
Polioksietilen oktil fenil eter
4-Oktilfenol polietoksilat
Siyah Beyaz 30
TX-100
t- Oktilfenoksipolietoksietanol
Oktoksinol-9
Triton X-100 Tanmlayclar
Triton X-100 CAS numaras
9002-93-1 ☑
Triton X-100 3B modeli ( JSmol )
Triton X-100 Etkileimli görüntü
Triton X-100 ECHA Bilgi Kart 100.123.919
Triton X-100PubChem Müteri Kimlii
5590
CompTox Kontrol Paneli ( EPA )
Triton X-100 Özellikleri
Triton X-100 Kimyasal formül C
14H
22O (C
2H
4O) n (n = 9-10)
Triton X-100 Molar kütle 647 g mol -1
Triton X-100 Görünüm viskoz renksiz sv
Triton X-100Younluk 1,07 g / cm 3
Triton X-100 Erime noktas 6 ° C (43 ° F; 279 K)
Triton X-100 Kaynama noktas 270 ° C (518 ° F; 543 K)
Triton X-100 sudaki çözünürlük Çözünür
Triton X-100 Yüzey gerilimi:
Triton X-100 CMC 0,22 mM [1]
Triton X-100 Buhar basnc 20 ° C’de <1 mmHg (130 Pa)
Triton X-100 Krlma indisi ( n D ) 1.490-1.494 [2]
Triton X-100 Tehlikeler
Güvenlik Bilgi Formu MSDS
Triton X-100 Alevlenme noktas 251 ° C (484 ° F; 524 K)
Aksi belirtilmedii sürece, veriler standart hallerinde (25 ° C [77 ° F], 100 kPa) malzemeler için verilmitir.
☑ dorula ( nedir ?) ☑☒
Bilgi kutusu referanslar
Triton X-100 ( C
14H
22O (C
2H
4O) n ) hidrofilik bir polietilen oksit zincirine (ortalama olarak 9.5 etilen oksit birimine sahiptir) ve aromatik bir hidrokarbon lipofilik veya hidrofobik gruba sahip iyonik olmayan bir yüzey aktif maddedir . Hidrokarbon grubu, bir 4- ( 1,1,3,3-tetrametilbutil ) – fenil grubudur. Triton X-100, IGEPAL CA-630 veya eski Nonidet P-40 ile yakndan ilgilidir bu, esasen biraz daha ksa etilen oksit zincirlerine sahip olmasyla farkllk gösterebilir. Bu nedenle Triton X-100, Igepal CA-630’dan biraz daha hidrofiliktir; bu iki deterjann çou uygulama için ilevsel olarak birbirinin yerine kullanlabilecei düünülmeyebilir. [3] Triton X-100 aslen Rohm & Haas Co.’nun tescilli ticari markasyd. Daha sonra Union Carbide tarafndan satn alnd ve daha sonra Union Carbide’n satn alnmasyla Dow Chemical Company tarafndan satn alnd . Ksa süre sonra (2009’da), Dow ayn zamanda Rohm & Haas Co.’yu da satn ald. Çok benzer bileiklerin dier ticari markalar arasnda Conco NI, Dowfax 9N, Igepal CO, Makon, Neutronyx 600’ler, Nonipol NO, Plytergent B, Renex 600’ler, Solar NO, Sterox, Serfonic N, T-DET-N, Tergitol NP, Triton N, vb. [4]
Triton X-100 deterjanlar uzaktan ilikili Pluronik aralnda deterjanlar tarafndan pazarlanan , BASF . Pluronikler, etilen oksit ve propilen oksidin triblok kopolimerleridir ve etilen oksit segmentleri propilen oksitten daha hidrofiliktir.
Fiziksel özellikler
Seyreltilmemi Triton X-100, hidrofilik polietilen oksit parçalarnn hidrojen ba sayesinde berrak viskoz bir svdr (seyreltilmemi gliserolden daha az viskozdur) . Seyreltilmemi Triton X-100, 25 ° C’de yaklak 270 centipoise’lk bir viskoziteye sahiptir ve 50 ° C’de yaklak 80 centipoise’a düer. Triton X-100, 25 ° C’de su, toluen, ksilen, trikloroetilen, etilen glikol, etil eter, etil alkol, izopropil alkol ve etilen diklorür içinde çözünür. Triton X-100, oleik asit gibi bir birletirme ajan kullanlmadkça, gazya, mineral ispirto ve nafta içinde çözünmez. [5]
kullanr
Triton X-100, laboratuvarlarda yaygn olarak kullanlan bir deterjandr . [6] Triton X-100, protein veya organelleri çkarmak için hücreleri parçalamak veya canl hücrelerin zarlarn geçirgen hale getirmek için yaygn olarak kullanlmaktadr. [7]
Baz uygulamalar unlar içerir:
Etkinliin yok edilmesine ilikin bir lipid zarfl virüsler (örnein , HIV , HBV , HCV imalat olarak) biyofarmasötik
Endüstriyel amaç (metal kaplama)
Fluzone dahil grip alarndaki içerik
Sabitlenmemi (veya hafifçe sabitlenmi) ökaryotik hücre zarlarn geçirgen hale getirme [7]
CHAPS gibi zwitteriyonik deterjanlar ile birlikte doal hallerinde çözünen membran proteinleri
Bölüm liziz tamponu içinde (genellikle alkalin lisiz tampon maddesi içinde bir% 5 çözelti içinde) DNA ekstraksiyonu
mmün boyama srasnda sulu çözeltilerin yüzey geriliminin azaltlmas (genellikle TBS veya PBS Tamponu içinde% 0.1-0.5 konsantrasyonda)
Yumuak kompozit malzemeler için karbon malzemelerin dalm
Mikrobiyolojide Aspergillus nidulans’ta koloni genilemesinin kstlanmas
Hayvan kaynakl dokularn hücresizletirilmesi
Jel içindeki proteinleri yeniden ekillendirmeden önce SDS’nin SDS-PAGE jellerinden çkarlmas
TEER ölçümleri için pozitif bir kontrol olarak hücre tek katmanlarnn bozulmas
Misel katalizör
Triton X-100, laboratuar kullanmnn yan sra, ar hizmet endüstriyel ürünlerden yumuak deterjanlara kadar çeitli temizlik bileiklerinde [8] bulunabilir . Ayn zamanda , saf su ve izopropil alkol ile birlikte ev yapm vinil plak temizleme svlarnda popüler bir bileendir . [9]
Triton X-100’ün REACH Yetkilendirme Listesine (Ek XIV) eklenmesi
Aralk 2012’de, Avrupa Kimyasallar Ajans (ECHA) , çok yüksek maddeler Aday Listesi’ne Triton X-100’ü içeren etoksillenmi 4- (1,1,3,3-tetrametilbutil) fenol madde grubunu dahil etti. endie [10] arasnda kimya Kayd, Deerlendirilmesi ve zne (REACH) Yönetmelii olan adresleri imal, ithal ve kimyasal maddelerin kullanm ve insan sal ve çevre üzerindeki potansiyel etkilerini. [11] Bir Triton X-100 bozunma ürününün, yaban hayat üzerinde etkili olabilecek hormon benzeri (östrojeno-mimetik) aktiviteye sahip olduu için gerçekten de ekotoksik olduu ortaya çkt. [12] ECHA sonunda madde grubunuYetkilendirme Listesi (Ek XIV) , [13] “son tarihine” 4 Ocak 2021 tarafndan bu deterjan yerine ilaç ve dier sanayi zorunlu böylece etkileyen AB ihracat üreticileri, ithalatçlar ve alt kullanclarna, hem de Avrupal olmayan üreticileri ürünlerini AB’ye dahil ediyor.
Viral inaktivasyon için alternatifler
Triton X-100’ün ruhsatlandrma açsndan çok yüksek önem arz eden maddeler aday listesine dahil edilmesinden dolay, ilaç firmalar ve biyoilem aratrma gruplar, ayn zamanda çevre dostu ve etkili olmas gereken alternatif bir deterjana ihtiyaç duymaktadr. . deal olarak, bir Triton X-100 deiiminin minimum üretim süreci deiiklii oluturmas gerekir, çünkü ancak o zaman ilaçlar için yasal düzenlemelerin gerekli güncellemeleri ek hayvan deneyleri ve hatta klinik aratrmalar olmadan gerçekletirilebilir. Bu nedenle, alternatif bir virüs etkisizletirici deterjan, Triton X-100’e benzer fiziko-kimyasal özelliklere sahip olmal, çözünür olmal, çkarmas kolay, çevre dostu olmal, ancak toksik metabolitlere indirgenmemelidir. Yakn zamanda yaplan bir çalmada, [14]biyofarmasötik üretiminde antiviral tedavi için iki alternatif tanmlanmtr: ndirgenmi Triton X-100 ve Nereid (Yunan mitolojisindeki deniz kzlarndan sonra) olarak adlandrlan yeni bir bileik. Adndan da anlalaca gibi, Nereid, Triton X-100 ailesinin baka bir akrabas olarak görülebilir, ancak küçük bir moleküler farkllk nedeniyle, Triton X-100’ün yapt gibi fenolik bileiklere dönümez. Virüs inaktivasyon çalmalar, çeitli koullar altnda çeitli ilgili virüslerle deneyleri içermektedir. Biyofarmasötik üretiminde virüs inaktivasyon admlarnn çounun gerçekletirildii oda scaklnda, hem Triton X-100 azaltlm hem de Nereid, Triton X-100 ile benzer virüs inaktive edici performanslar gösterdi. Buna karlk, souk scaklklarda gerçekletirilen baz ilemler için, Nereid ve Triton X-100, indirgenmi Triton X-100’den daha iyi sonuçlar verdi. Bugüne kadar Nereid, üç aamal bir sentez kullanlarak kilogram ölçeinde üretilebiliyor ve bir patent bavurusu yapld.[15] Nereid ölçeklenebilir ve mevcut süreçlerle uyumludur ve u ana kadar ürün etkinlii üzerinde herhangi bir etki göstermemitir. Performans açsndan, Nereid, Triton X-100 için salam bir “hepsi bir arada” yedek olacaktr. Bu nedenle, çevre açsndan güvenli olduunu dorulamak için u anda ekotoksikoloji ve biyolojik bozunma çalmalarnda test edilmektedir.
TRTON X-100
Triton X-100
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Page d’aide sur l’homonymie Pour les articles homonymes, voir Triton.
Triton X-100
Image illustrative de l’article Triton X-100
Structure du Triton X-100
Identification of Triton X-100
No CAS 9002-93-1
No ECHA 100.123.919
SMILES
[Afficher]
InChI
[Afficher]
Propriétés chimiques du Triton X-100
Formule brute du Triton X-100 C33H60O10.5
Masse molaire du Triton X-1001 624,8232 ± 0,0338 g/mol
C 63,43 %, H 9,68 %, O 26,89 %,
Propriétés physiques du Triton X-100
Masse volumique du Triton X-100 1,06 kg·L-1[réf. souhaitée]
Point d’éclair du Triton X-100 251 °C[réf. souhaitée]
Précautions du Triton X-100
SIMDUT2
Produit non classé
[+]
Écotoxicologie du Triton X-100
DL50 1 200 mg·kg-1 (souris, i.v.)3
Unités du SI et CNTP, sauf indication contraire.
modifier Consultez la documentation du modèle
Le Triton X-100 est un détergent de synthèse de formule brute C8H17C6H4(OC2H4)9-10OH.
Triton X-100 est utilisé en biologie cellulaire et moléculaire pour perméabiliser les membranes cytoplasmiques, nucléaires, etc. Ceci permet par exemple aux anticorps d’avoir accès au noyau de la cellule lors de la réalisation d’une immunocytochimie.