1,2 BENZISOTHIAZOLIN 20% (BIT 20%)

1,2-Benzisothiazolin 20%

SYNONYMS;

2634-33-5; 1,2-Benzisothiazol-3(2H)-one; 1,2-Benzisothiazolin-3-one; 1,2-benzothiazol-3-one; benzisothiazolone; Benzo[d]isothiazol-3(2H)-one; Benzo[d]isothiazol-3-one; Proxel; 1,2-Benzisothiazoline-3-one; Proxel PL; Benzo[d]isothiazol-3-ol; 2,3-dihydro-1,2-benzothiazol-3-one; Nipacide BIT; Proxel AB; Proxel XL 2; 1,2-BENZISOTHIAZOL-3-ONE; benzoisothiazol-3-one; 1,2-benzoisothiazolin-3-one; 1,2-Benzisothiazolone; Caswell No. 079A; Caswell No. 513A; C7H5NOS; UNII-HRA0F1A4R3; CCRIS 6369; 3-Hydroxy-1,2-benzisothiazole; IPX; CHEBI:167099; EINECS 220-120-9; EPA Pesticide Chemical Code 098901; HRA0F1A4R3; 1,2-Benzoisothiazoline-3-one; 40991-37-5; DMSMPAJRVJJAGA-UHFFFAOYSA-N; 2,3-dihydro-3-oxo-1,2-benzisothiazole; MLS-0254244.0001; Benzo(d)isothiazol-3(2H)-one; Benzisothiazolin-3-one; Benzocil; Acticide BIT; Canguard BIT; Denicide BIT; Proxel BD; Proxel CF; Proxel TN; Proxel XL; Proxel BDN; Proxel GXL; Proxel Ultra 5; San-aibac AP; Proxel LV-S; Proxel Press Paste; Apizas AP-DS; Acticide BW 20; Bestcide 200K; Nipacide BIT 20; Parmetol B 70; Parmetol D 11; Proxel GXL(S); Proxel HL 2; Nuosept 485; Nuosept 491; Nuosept 495; Topcide 600; XBINX; Denicide BIT 20N; Koralone B 119; Nipacide BIT 10W; Preventol BIT 20D; Proxel BD 20; Proxel Press Paste D; Troysan 1050; Bioban BIT 20DPG; benzisothiazoline-3-one; Canguard BIT 20DPG; 1,2-benzisothiazolinone; SD 202 (bactericide); Canguard Ultra BIT 20LE; 1,2-Benzoisothiazol-3-one; BIT 10W; BIT 20; 2-Thiobenzimide; 2,3-Dihydrobenzisothiazol-3-one; 1,2-benzisothiazole-3(2h)-one; SD 202; 1,2-Benzothiazolinone; PubChem15685; Benzisothiazolone (BIT); ACMC-209u7v; Epitope ID:115004; Benzisothiazol-3(2H)-one; DSSTox_CID_12523; DSSTox_RID_78967; DSSTox_GSID_32523; SCHEMBL26078; cid_17520; KSC201Q7J; MLS000771034; REGID_for_CID_17520; CHEMBL297304; SCHEMBL5586024; DTXSID5032523; BDBM46658; CTK1A1874; HSDB 8271; 1,2-BIT; HMS1755P21; HMS2706H20; 1,2-Benzisothiazol-3-one (BIT); KS-00000E5U; ZINC2581983; Tox21_300489; ANW-43433; MFCD00127753; AKOS001062434; AKOS030227972; AC-2653; CS-W018117; FS-3163; MCULE-3257757873; NE11261; 1,2-BENZISOTHAZOL-3(2H)-ONE; 1,2-Benzisothiazol-3(2H)-one, 97%; NCGC00164206-01; NCGC00248077-01; NCGC00254467-01; BR-46705; LS-33607; SC-15324; SMR000344133; US9011882, Table 1, Compound 20; CAS-2634-33-5; AB0008332; AB1001358; DB-027306; AM20060449; B2430; FT-0606282; EN300-17679; 34B335; M-4954; 634B335; A818398; AE-562/40151878; Q411746; 1,2-Benzisothiazol-3(2H)-one, analytical standard; W-107178; Z56983154; F0288-0100; InChI=1/C7H5NOS/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9; bit20; BIT20%; BENZISOTHIAZOLE 20; benziso thiazole 20; benz-iso-thiazole; Bit %20

Benzisothiazolinone has a microbicide and a fungicide mode of action. It is widely used as a preservative, for example in: emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions home cleaning and car care products; laundry detergents, stain removers and fabric softeners; industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins agriculture in pesticide formulations gas and oil drilling in muds and packer fluids preservation.[2]:iv In paints, it is commonly used alone or as a mixture with methylisothiazolinone. Typical concentrations in products are 200-400 ppm depending on the application area and the combination with other biocides. According to a study in Switzerland, 19% of the paints, varnishes and coatings contained BIT in 2000. The fraction in adhesives, sealants, plasters and fillers was shown at that time as 25%.[3] A later study in 2014 shows a dramatic rise in usage, to 95.8% of house paints.[4]

Benzo[d]isothiazol-3-one is an organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion. It has a role as a disinfectant, a platelet aggregation inhibitor, an environmental contaminant, a xenobiotic, a drug allergen and a sensitiser. It is an organonitrogen heterocyclic compound and an organic heterobicyclic compound.

PubChem CID: 17520

Property Name Property Value

XLogP3-AA 1.3

Hydrogen Bond Donor Count 1

Rotatable Bond Count 0

Exact Mass 151.009185 g/mol

Monoisotopic Mass 151.009185 g/mol

Topological Polar Surface Area 54.4 Å²

Heavy Atom Count 10

Formal Charge 0

Complexity 160

Color/Form : Off-white to yellowish solid -European Commission; Opinion on Benzisothiazolinone,

White to off-white fine, crystalline powder – Dow Chemical; Product Safety Assessment. 1,2-Benisothiazol-3(2H)-one (BIT)

Technical product (commercial) can be in the form of a solid paste that is off-white to brown in color – USEPA/OPPTS; Reregistration Eligibility Decisions (REDs) Database on 1,2-Benzisothiazolin-3-one (BIT)

Boiling Point : 327.6 °C

Melting Point : 156.6 °C

Solubility :In water, 1.1 g/L at 20 °C; 0.938 g/L at 20 °C and pH 4.8; 1.288 g/L at 20 deg and pH 6.7; 1.651 g/L at 20 °C at pH 9.1; 1.198 g/L at 30 °C pH 4.8

Density :1.483 g/cu cm at 20 °C

Vapor Pressure:2.78X10-6 mm Hg at 25 °C

Stability/Shelf Life : Stable under recommended storage conditions – Sigma-Aldrich; Safety Data Sheet for 1,2-Benzisothiazol-3(2H)-one.

Function and uses

Benzisothiazolinone is listed in the EU Cosmetics Inventory, Section 1 with indicated function “antimicrobial”. It is currently not regulated in the annexes of the Cosmetics Directive 76/768/EEC. The submitted dossier requests a maximum level of 100 ppm as preservative in cosmetic products. This is greater than the level proposed in the earlier submission, which the applicant justifies with the availability of more recent studies, demonstration of a greater margin of safety. Aside from its use in cosmetic products, there are also other uses: Under the Biocide review programme for existing substances (Commission Regulation (EC) No 1451/2007), Benzisothiazolinone is examined for use in the following product types: SCCS/1482/12 Opinion on benzisothiazolinone

Private area and public health area disinfectants and other biocidal products (2), In-can preservatives (6), Film preservatives (7), Fibre, leather, rubber and polymerised materials preservatives (9), Masonry preservatives (10), Preservatives for liquid-cooling and processing systems (11), Slimicides (12), Metalworking-fluid preservatives (13), Embalming and taxidermist fluids (22). Benzisothiazolinone is used as a slimicide in the manufacture of disposable powder-free polyvinyl chloride gloves. Benzisothiazolinone is widely used in industry as a preservative in water-based solutions such as pastes, paints and cutting oils.

BIT 20 1 2-Benzisothiazolin 3 one 20% solution CAS 2634-33-5

CAS:2634-33-5

Purity:20%

Appearance:Amber liquid

Package: 25kg,200kg,1.25mt drum

Product description: BIT-20 is a new generation Broad-spectrum preservatives benzisothiazolin. Widely used in Latex paint、Waterborne wood coatings、Waterborne polymers、adhesive、inks、Dyedispersion、Liquid paraffin etc.

BIT-20 biocide benzisothiazolinone ; In-Can Preservation for Paints, Adhesives and Related Products

BIT-20/ 1,2-Benzisothiazolin-3-one

CAS:2634-33-5

Purity: 20% liquid

Solvent: DPG, or PG

General

BIT-20 biocide is a broad spectrum microbicide for the preservation of industrial water-based products against the attack of microorganisms. The Composition of BIT-20 is 20% solution of 1,2-Benzisothiazolin-3-one in dipropylene glycol and water.

BIT-20 is specifically recommended for the preservation of polymer emulsions, paints and coatings, adhesives, and printing inks.

Application field

Suitable for applications in the water-based polymer, leather, paint, textile, printing and dyeing, metal cutting fluids, adhesives, inks, dyes, dye dispersions industries to resist corrosion.

Performance characteristics

1. Serve as a broad-spectrum, long-lasting biocide to kill many bacteria, fungi and yeasts; the liquid with a lowest concentration of 0.1% will have a good antibacterial effect;

2. Good compatibility with all kinds of emulsifiers, surfactants and other agents; miscible in the solutions of alcohol and water at any ratio.

3. Wider applications that like products; suitable for use in the medium of the pH value in the range of 4.0-12.

4. Excellent inactivity, with the active ingredient able to withstand a high temperature of 150 ℃.

5. Low toxicity; contain no heavy metals and halogen compounds; inactive to amines; free of formaldehyde.

Usage and Cautions

1. For use in cosmetics, body care products, and other daily chemicals, the concentration of using is in the range of 0.05-0.40% (w/w) depending on the storage environment and whether the product is susceptible to the destroy of microorganisms. The specific formula and instructions for the concentration of using will be based on the company’s microbial technology division

2. It can be added at any production step; but it’s suggested to be added at the final step at less than 50 ℃; avoid adding at a temperature of higher than 50 ℃.

3. Wear protective clothing, rubber gloves and goggles and masks, avoid contact with skin, eyes and mucous membranes.

Safety: In an acute oral toxicity test, the LD50 in rats is 2500 mg/kg.

Packaging : 25kg, 200 kg per plastic drum; 1mt IBC drum; Or as your request;

Storage and Transportatio : With a shelf time of one year when stored at room temperature in a dark, air-tight, and moisture-proof place.

Product Description

Benzisothiazolinone (BIT) is a widely used biocide and belongs to the group of isothiazolinones.

Benzisothiazolinone has a microbicide and a fungicide mode of action. It is widely used as a preservative, for example in:

-Emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions;-Home cleaning and car care products; laundry detergents, stain removers and fabric softeners;-Industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins;-Agriculture in pesticide formulations;-Gas and oil drilling in muds and packer fluids preservation.

Health hazards

Given sufficient dose and duration, dermal exposure can produce skin sensitization and allergic contact dermatitis,[5] and is classified as an irritant for skin and eyes.[1] Benzisothiazolinone has also been linked with Systemic Contact Dermatitis via airborne contact.[6] In 2012, the Scientific Committee on Consumer Safety in Europe found BIT’s “sensitising potential is of concern…Sensitisation from related isothiazolinones is an important problem in consumers. This has occurred because there has been consumer exposure before safe levels of exposure relevant to sensitisation have been established. Benzisothiazolinone is a skin sensitiser in animal models with potency similar to methylisothiazolinone. Methylisothiazolinone, at 100 ppm (0.01%) in cosmetic products is causing contact allergy and allergic contact dermatitis in the consumer. Benzisothiazolinone is known to be a sensitiser in man and has induced sensitisation at circa 20 ppm in gloves.”[7] The opinion further states: “There is no information on what may be safe levels of exposure to benzisothiazolinone in cosmetic products from the point of view of sensitisation. Until safe levels of exposure have been established, the use of benzisothiazolinone in cosmetic products as a preservative or for other functions cannot be considered safe in relation to sensitisation.” Later, in 2013, researchers published a study that set out to derive the highest concentration of BIT in certain consumer products that would result in exposures below the No Expected Sensitization Induction Level (NESIL); that is, where normal use would yield a dose below the level at which skin sensitization might occur. The products under consideration were sunscreen, laundry detergent, dish soap, and spray cleaner; by way of calculation they derived BIT NESILs of 0.0075%, 0.035%, 0.035%, 0.021%, respectively. They then performed a pilot examination via bulk sample analysis of one representative product from each category labelled as containing BIT. Their findings showed all BIT concentrations well below the derived NESIL, with 0.0009% and 0.0027% for sunscreen and dish soap, respectively, and no detection in the laundry detergent and spray cleaner products, meaning the concentration was at or below the limit of detection of 0.0006%.

BIT; BIT 20; Acticide B 20; Proxel GXL; Nipacide BIT 20; 1,2-Benzisothiazolin-3-one cas no :2634-33-5; EC: 220-120-9; 1,2-benzisothiazol-3(2H)-one; Benzisothiazolinone, Benzisothiazolin-3-one, Benzisothiazolone;1,2-benzisothiazol-3(2H)-one

;1,2-benzisothiazolin-3-one; 1,2-Benzisothiazoline-3-one

Benzisothiazolinone (BIT) is a widely used biocide and belongs to the group of isothiazolinones.

Usage

Benzisothiazolinone has a microbicide and a fungicide mode of action. It is widely used as a preservative, for example in:

emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions

home cleaning and car care products; laundry detergents, stain removers and fabric softeners;

industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins

agriculture in pesticide formulations

gas and oil drilling in muds and packer fluids preservation.

In paints, it is commonly used alone or as a mixture with methylisothiazolinone. Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides. According to a study in Switzerland, 19% of the paints, varnishes and coatings contained BIT in 2000. The fraction in adhesives, sealants, plasters and fillers was shown at that time as 25%.[3] A later study in 2014 shows a dramatic rise in usage, to 95.8% of house paints.

Health hazards

Given sufficient dose and duration, dermal exposure can produce skin sensitization and allergic contact dermatitis, and is classified as an irritant for skin and eyes. Benzisothiazolinone has also been linked with Systemic Contact Dermatitis via airborne contact.

In 2012, the Scientific Committee on Consumer Safety in Europe found BIT’s “sensitising potential is of concern…Sensitisation from related isothiazolinones is an important problem in consumers. This has occurred because there has been consumer exposure before safe levels of exposure relevant to sensitisation have been established. Benzisothiazolinone is a skin sensitiser in animal models with potency similar to methylisothiazolinone. Methylisothiazolinone, at 100 ppm (0.01%) in cosmetic products is causing contact allergy and allergic contact dermatitis in the consumer. Benzisothiazolinone is known to be a sensitiser in man and has induced sensitisation at circa 20 ppm in gloves.

The opinion further states: “There is no information on what may be safe levels of exposure to benzisothiazolinone in cosmetic products from the point of view of sensitisation. Until safe levels of exposure have been established, the use of benzisothiazolinone in cosmetic products as a preservative or for other functions cannot be considered safe in relation to sensitisation.”

Later, in 2013, researchers published a study that set out to derive the highest concentration of BIT in certain consumer products that would result in exposures below the No Expected Sensitization Induction Level (NESIL); that is, where normal use would yield a dose below the level at which skin sensitization might occur. The products under consideration were sunscreen, laundry detergent, dish soap, and spray cleaner; by way of calculation they derived BIT NESILs of 0.0075%, 0.035%, 0.035%, 0.021%, respectively. They then performed a pilot examination via bulk sample analysis of one representative product from each category labelled as containing BIT. Their findings showed all BIT concentrations well below the derived NESIL, with 0.0009% and 0.0027% for sunscreen and dish soap, respectively, and no detection in the laundry detergent and spray cleaner products, meaning the concentration was at or below the limit of detection of 0.0006%

Acticide B 20 is a clear glycol based BIT solution. Acts as a biocide. Provides complete wet state preservation. Acticide® B 20 is used in a wide range of aqueous based products.

Proxel GXL by Lonza is a 20% aqueous dipropylene glycol solution of 1,2-benzisothiazolin-3-one. Used for the preservation of industrial water-based products against spoilage from bacteria, yeasts and fungi. It has a non-specific mode of action which means that bacterial resistance is very unlikely to occur. It boils without flashing and is stable in the presence of amines. The concentration of Proxel® GXL required to adequately preserve your product depends on several factors. These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved, pH, temperature, and length of time for which protection is required. Suitable for use in synthetic polymer emulsions, emulsion paints, printing inks, paper coating compositions. Recommended dosage is 0.05-0.15% w/w for these applications.

PROXEL GXL is a broad spectrum biocide for the preservation of industrial water-based products against spoilage from bacteria, yeasts and fungi.

PROXEL GXL is a 20% aqueous dipropylene glycol solution of 1,2-benzisothiazolin-3-one.

Applications

PROXEL GXL is effective in a wide range of industrial aqueous-based products. Application areas include:

• Synthetic polymer emulsions

• Emulsion paints

• Water-based adhesives

• Household products

• Printing inks

• Paper coating compositions

• Metal working fluids

• Agricultural pesticide dispersions

• Aqueous mineral and pigment slurries

• Tape joint compounds

• Leather processing solutions

Antimicrobial Properties

The levels of PROXEL GXL needed to prevent the growth of problem micro-organisms are listed in Table 1.

MICs do not represent effective use levels but do indicate the broad spectrum of activity of PROXEL GXL.

PROXEL GXL has a non-specific mode of action which means that bacterial resistance is very unlikely to occur.

Detailed information on the mode of action of PROXEL GXL is available on request.

Table 1: Minimum Inhibitory Concentrations (MIC)

Micro-organism PROXEL GXL (ppm)

Bacteria

Bacillus subtilis: 40

Burkholderia cepacia: 80

Enterobacter cloacae: 80

Escherichia coli: 40

Proteus vulgaris: 125

Pseudomonas aeruginosa: 250

Pseudomonas putida: 250

Staphylococcus aureus: 40

Streptococcus faecalis: 40

Streptococcus lactis: 15

Fungi

Alternaria alternata: 700

Aspergillus niger: 350

Aureobasidium pullulans: 350

Chaetomium globosum: 400

Cladosporium cladosporoides: 400

Penicillium notatum: 125

Yeasts

Candida albicans: 200

Rhodotorula rubra: 400

Saccharomyces cerevisiae (turbidans): 250

Table 2: Typical Physical Properties

Composition A solution of 1,2-benzisothiazolin3-one in dipropylene glycol and water.

Active agent: 20% w/w

Physical form : Yellow-light brown solution

Viscosity at 10/25°C : 2000/400 mPa s (Newtonian)

pH at 25°C: 13.5

Boiling point: 100°C

Storage stability Stable under normal conditions of storage down to -10°C. If frozen, allow to thaw and stir well before use. Active agent is heat-stable and non-volatile.

Flash point: Boils without flashing

Density at 25°C: 1.14

Compatibility: Compatible and effective over pH range 4-12. Stable in the presence of amines. Incompatible with some oxidising and reducing agents e.g. persalts, sulphites.

Amount to Use

PROXEL GXL should be added to the system as early in the process as possible. The concentration of PROXEL GXL required to adequately preserve your product depends

on several factors. These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved,

pH, temperature, and length of time for which protection is required.

A range of concentrations and applications is recommended in Table 3; however, it is recommended that a testing programme be undertaken to determine the most costeffective dose for your application.

Testing should take into account chemical compatibility/stability, plant hygiene conditions, susceptibility of the product to contamination, and the typical organisms involved.

1,2-Benzisothiazol-3(2H)-one, also known as benzisothiazolone or proxel, belongs to the class of organic compounds known as benzothiazoles. These are organic compounds containing a benzene fused to a thiazole ring (a five-membered ring with four carbon atoms, one nitrogen atom and one sulfur atom). 1, 2-Benzisothiazol-3(2H)-one exists as a solid, slightly soluble (in water), and a very weakly acidic compound (based on its pKa). Within the cell, 1, 2-benzisothiazol-3(2H)-one is primarily located in the cytoplasm. 1, 2-Benzisothiazol-3(2H)-one is a potentially toxic compound.

Table 3: Applications

Product % PROXEL GXL (w/w)

Synthetic polymer emulsions: 0.05-0.15

Emulsion paints: 0.05-0.15

Water-based adhesives: 0.05-0.25

Household products: 0.05-0.15

Including

Laundry detergents, Fabric softeners,

Dish-washing liquids, Floor and wall

cleaning solutions, Surface cleaning

products, Window cleaners,

Floor polishes and waxes, Shoe polishes

Tape joint compounds: 0.05-0.25

Printing inks: 0.05-0.15

Paper coating compositions: 0.05-0.15

Metal working fluids: 0.05-0.18

Agricultural pesticide products: 0.05-0.25

Aqueous mineral and pigment slurries: 0.05-0.15

Leather processing solutions: 0.05-0.25

For the short term preservation of freshly flayed skins & hides during processing

1,2-benzisothiazol-3(2H)-one

1,2-benzisothiazolin-3-one

1,2-Benzisothiazoline-3-one

Translated names

1,2,bencisotiazol-3-ona (es)

1,2-bencisotiazol-3(2H)-ona (es)

1,2-Bencisotiazol-3(2H)-ona (BIT) (es)

1,2-bensisotiasool-3(2H)-oon (et)

1,2-bensisotiasool-3(2H)-oon (BIT) (et)

1,2-bensisotiasool-3-oon (et)

1,2-bensisotiazol-3(2H)-on (BIT) (sv)

1,2-bentsisotiatsol-3(2H)-oni (fi)

1,2-bentsisotiatsol-3(2H)-oni (BIT) (fi)

1,2-bentsisotiatsolin-3-oni (fi)

1,2-benzisothiazol-3(2H)-on (da)

1,2-Benzisothiazol-3(2H)-on (BIT) (de)

1,2-benzisothiazol-3(2H)-one (BIT) (no)

1,2-benzisothiazol-3(2H)-one;1,2-benzisothiazolin-3-one (fr)

1,2-benzisothiazole-3(2H)-one (BIT) (fr)

1,2-Benzisothiazolin-3-on (de)

1,2-benzisothiazool-3(2H)-on (nl)

1,2-Benzisothiazool-3(2H)-on (BIT) (nl)

1,2-benzisotiazol-3(2<I>H</I>)-on (hr)

1,2-benzisotiazol-3(2H)-on (no)

1,2-benzisotiazol-3(2H)-ona (pt)

1,2-benzisotiazol-3(2H)-ona (BIT) (pt)

1,2-benzisotiazol-3(2H)-one (it)

1,2-benzisotiazol-3(2H)-one (BIT) (it)

1,2-benzisotiazol-3(2H)-onă (BIT) (ro)

1,2-benzisotiazolin-3-on (hr)

1,2-benzisotiazolin-3-ona (ro)

1,2-benzizotiazol-3(2H)-on (hu)

1,2-benzizotiazol-3(2H)-on (BIT) (hr)

1,2-benzizotiazol-3(2H)-onas (lt)

1,2-benzizotiazol-3(2H)-onas (BIT) (lt)

1,2-benzizotiazol-3(2H)-ons (lv)

1,2-Benzizotiazol-3(2H)-ons (BIT) (lv)

1,2-benzizotiazol-3(2H)-ón (sk)

1,2-benzizotiazol-3(2H)-ón (BIT) (sk)

1,2-benzizotiazolin-3-on (hu)

1,2-benzizotiazolin-3-onas (lt)

1,2-benzizotiazolin-3-ons (lv)

1,2-benzizotiazolín-3-ón (sk)

1,2-benzoisothiazol-3(2H)-on (BIT) (cs)

1,2-benzoisothiazol-3(2H)-on+ (cs)

1,2-benzoisothiazolin-3-on (cs)

1,2-benzoizotiazol-3(2H)-on (pl)

1,2-benzoizotiazolin-3-on (pl)

1,2-Benżisotijażol-3(2H)-on (BIT) (mt)

1,2-βενζισοθειαζολ-3(2H)-όνη (el)

1,2-βενζισοθειαζολ-3(2H)-όνη (BIT) (el)

1,2-бензизотиазол-3(2H)-oн (bg)

1,2-бензизотиазол-3(2H)-он (BIT) (bg)

1,2-бензизотиазолин-3-oн (bg)

IUPAC names

1 ,2-benzisothiazol-3-(2H)-one

1,2-benzisothiazol-3(2H) -one

1,2-benzisothiazol-3(2H)-one, sodium salt

1,2-benzisothiazol-3(2H)-one/1,2-benzisothiazolin-3-one

1,2-benzisothiazol-3-one

1,2-BENZOTHIAZOL-3(2H)-ONE

1,2-Benzothiazol-3-one

2,3-dihydro-1,2-benzothiazol-3-one

Benzisothiazol- 3(2h)-one

benzo[d]isothiazol-3-one

Proxel

Other identifiers

101964-01-6

Other

CAS number

1094749-54-8

Other

CAS number

1148150-72-4

Other

CAS number

1376937-61-9

Other

CAS number

1399460-92-4

Other

CAS number

2634-33-5

CAS number

40991-37-5

Other

CAS number

54392-14-2

Other

CAS number

552320-00-0

Other

CAS number

613-088-00-6

Index Number

75037-67-1

Other

CAS number

919284-21-2

Other

CAS number

934197-15-6

1,2-Benzisothiazol-3(2H)-one

2634-33-5

1,2-Benzisothiazolin-3-one

1,2-benzothiazol-3-one

benzisothiazolone

benzisothiazolinone

Benzo[d]isothiazol-3(2H)-one

Benzo[d]isothiazol-3-one

Proxel

1,2-Benzisothiazoline-3-one

Proxel PL

Benzo[d]isothiazol-3-ol

2,3-dihydro-1,2-benzothiazol-3-one

1,2-benzisothiazolinone

Nipacide BIT

Proxel AB

Proxel XL 2

1,2-BENZISOTHIAZOL-3-ONE

benzoisothiazol-3-one

1,2-benzoisothiazolin-3-one

1,2-Benzisothiazolone

3-Hydroxy-1,2-benzisothiazole

IPX

CHEBI:167099

EINECS 220-120-9

EPA Pesticide Chemical Code 098901

1,2-Benzoisothiazoline-3-one

40991-37-5

2,3-dihydro-3-oxo-1,2-benzisothiazole

MLS-0254244.0001

Benzo(d)isothiazol-3(2H)-one

Benzisothiazolin-3-one

Benzocil

Acticide BIT

Canguard BIT

Denicide BIT

Proxel BD

Proxel CF

Proxel TN

Proxel XL

Proxel BDN

Proxel GXL

Proxel Ultra 5

San-aibac AP

Proxel LV-S

Proxel Press Paste

Apizas AP-DS

Acticide BW 20

Bestcide 200K

Nipacide BIT 20

Parmetol B 70

Parmetol D 11

Proxel GXL(S)

Proxel HL 2

Nuosept 485

Nuosept 491

Nuosept 495

Topcide 600

XBINX

Denicide BIT 20N

Koralone B 119

Nipacide BIT 10W

Preventol BIT 20D

Proxel BD 20

Proxel Press Paste D

Troysan 1050

Bioban BIT 20DPG

1,2-benzisothiazole-3(2h)-one

benzisothiazoline-3-one

Canguard BIT 20DPG

SD 202 (bactericide)

Canguard Ultra BIT 20LE

1,2-Benzoisothiazol-3-one

BIT 10W

BIT 20

2-Thiobenzimide

2,3-Dihydrobenzisothiazol-3-one

1,2-Benzothiazolinone

Benzisothiazolone (BIT)

Benzisothiazol-3(2H)-one

1,2-benzothiazol-3(2h)-one

1,2-benzisothiazol-3(2H)-on

1,2-BIT

1,2-Benzisothiazol-3-one (BIT)

1,2-BENZISOTHAZOL-3(2H)-ONE

1,2-Benzisothiazol-3(2H)-one, 97%

CAS-2634-33-5

1,2-Benzisothiazol-3(2H)-one, analytical standard

75037-67-1

1,2-Benzisothiazol-3(2H)-one [ACD/Index Name]

1,2-Benzisothiazol-3-ol [ACD/Index Name]

1,2-Benzothiazol-3(2H)-on [German] [ACD/IUPAC Name]

1,2-Benzothiazol-3(2H)-one [ACD/IUPAC Name]

1,2-Benzothiazol-3(2H)-one [French] [ACD/IUPAC Name]

1,2-Benzothiazol-3-ol [German] [ACD/IUPAC Name]

1,2-Benzothiazol-3-ol [ACD/IUPAC Name]

1,2-Benzothiazol-3-ol [French] [ACD/IUPAC Name]

220-120-9 [EINECS]

2634-33-5 [RN]

BENZISOTHIAZOLINONE

Benzisothiazolone [Wiki]

Benzisothiazolone (BIT)

benzo[d]isothiazol-3-one

[2634-33-5]

1,2-BENZISOTHAZOL-3(2H)-ONE

1,2-Benzisothiazol-3-one

1,2-Benzisothiazolin-3-one

1,2-Benzisothiazolinone

1,2-Benzisothiazolone

1,2-benzoisothiazolin-3-one

1,2-Benzoisothiazoline-3-one

1,2-Benzothiazol-3-one

1,2-Benzothiazolinone

119510

2,3-dihydro-1,2-benzothiazol-3-one

2,3-dihydro-3-oxo-1,2-benzisothiazole

‘2634-33-5

2-hydrobenzo[d]isothiazol-3-one

2-Thiobenzimide

3-Hydroxy-1,2-benzisothiazole

54392-15-3 [RN]

75037-67-1 [RN]

9015-68-3 [RN]

Acticide BIT

Benzisothiazol-3(2H)-one

BENZISOTHIAZOLINONE|”1,2-BENZOTHIAZOL-3-OL”

Benzo(D) Isothiazol-3-one

benzo[d]isothiazol-3(2H)-one

Benzo[d]isothiazol-3-ol

Benzoisothiazol-3-one

Benzoisothiazol-3-one|1,2-Benzisothiazol-3(2H)-one|3-Hydroxy-1,2-benzisothiazole

BIT

BR-46705

EINECS 220-120-9

Nipacide BIT

proxan

Proxel

Proxel AB

Proxel PL

Proxel XL 2

PROXELCRL

Nipacide BIT 20 is an in-can biocide based on BIT.

Nipacide BIT 20 is a glycol based solution; low toxicity biocide developed for the complete in-can protection of water based products. Nipacide BIT 20 is effective against a wide range of microorganisms including gram positive and gram negative bacteria, yeast and fungi.

Nipacide BIT 20 can be used over a wide pH and temperature range. Nipacide BIT 20 should be the biocide of choice for products with pH >8 and production temperatures of >40 C.

Benefits

formaldehyde-free

pH stable from 2-12

temperature stable up to 100°C

FDA approved for various applications

bactericide

fungicide

PREVENTOL BIT 20 N

Approx. 20 % aqueous-glycolic solution of 1,2-Benzisothiazolin-3-one (BIT).

For the preservation of aqueous coatings, polymer dispersions, plasters, synthetic adhesives, pigment slurries, concrete additives or cleaners and detergents.

The product has a broad spectrum of activity covering bacteria, mould and yeasts.

Use biocides safely. Always read the label and product information before use.

Genel

BIT-20 biyosit, mikroorganizmalarn saldrsna kar endüstriyel su bazl ürünlerin korunmas için geni spektrumlu bir mikrobisittir. Bileimi BIT-20 20% çözüm 1,2-Benzisothiazolin-3-one çin’de dipropilen glikol ve su.

BIT-20, polimer emülsiyonlarnn, boyalarn ve kaplamalarn, yaptrclarn ve bask mürekkeplerinin korunmas için özellikle tavsiye edilir.

Görünüm : Açk kehribar sv

Aktif Madde : 20%

PH (10% suda) : 11.0-13.0

Özgül arlk (g/ml) : 1.14 25 °C

Scaklk kararll : 50 ° c’ye kadar sabit (matrise bal olarak 100 ° c’ye kadar ksa süreler için)

PH stabilite : PH 4-12 ‘de kararl

Ürün Faydalar

1. yüksek pH sistemlerinde geni spektrumlu aktivite, bakteri, mantar ve mayalar kontrol eder.

2. aminlerin varlnda kararl.

3. spesifik olmayan etki modu, azaltlm mikrobiyal direnç potansiyeline neden olur.

4. sv formu ve çou sulu kompozisyonlarda iyi uyumluluk nedeniyle kullanm kolayl.

5. performans gelitirmeleri ve maliyet azaltma salayan CMI/MI, bronopol veya formaldehit releasers gibi ko-biyositler ile mükemmel performans.

6. aktif madde uçucu deildir ve hala scak olan svlarda birleme salayan nispeten yüksek bir s stabilitesine sahiptir.

7. açk açk renk ile belirgin yüksek saflkta aktif madde.

Antimikrobiyal Özellikler

Önerilen doz seviyelerinde kullanlan BIT-20 biyosit aadaki mikroorganizmalara kar etkilidir:

Pseudomonas aeruginosa, Fusarium solani,Pseudomonas fluorescens,Aspergilus nijer,Pseudomonas putida Alternaria alternata,Escherichia coli Aureobasidium pullulans,Klebsiella pneumoniae Chaetomium globosum,Enterobacter cloacae,Citrobacter freundii,Proteus vulgaris,Staphylococcus aureus

Yönlü Kullanm için

Aada baz genel dozlama önerileri vardr, ancak en uygun doz seviyelerini belirlemek için son üründe özel test yaplmas önerilir.

Ürün BIT-% 20 (Ürünün toplam arlna göre)

Polimer Emülsiyonlar:

Stiren 0.05-0.15% dayal polimer emülsiyonlar

Akrilik, akrilik, bütadien, PVA ve

Çeitli uygulamalar için stiren.

Emülsiyonlar boyalar ve kaplamalar 0.05-0.25%

Su bazl yaptrclar 0.05-0.25%

Bask mürekkepleri ve çeme çözümleri 0.05-0.15%

Svalar 0.05-0.25%

Kazanlar gibi yap malzemeleri, 0.08-0.25%

Szdrmazlk maddeleri, grouts, aralkl, hazr karm çimentosu,wallboard bileikleri ve bant eklemi bileikleri.

Matkap çamurlar gibi ya geri kazanm malzemeleri,

Packer svlar ve tamamlama svlar, 0.05-0.15%

Polisakkarit sv kayb kontrol maddeleri ve/veya kalnlatrc içeren Gibi niastas.

Katk maddeleri içeren ikincil ya geri kazanm enjeksiyon suyu,

Kalnlatrc kullanarak polimer veya micellar/polimer su taknlar gibi 0.015-0.15%

Gibi ksantan sakz.

Ambalaj

Davul bana 25Kg, davul bana 200Kg veya IBC davul bana 1000Kg.

1,2 BENZISOTHIAZOLIN 20% (BIT 20%)

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1,2 BENZISOTHIAZOLIN 20% (BIT 20%)

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