1,3-Butylene glycol
1,3-Butanediol = 1,3-Butylene glycol
Synonym(s): 1,3-Butylene glycol
Other names: β-Butylene glycol; Methyltrimethylene glycol; 1-Methyl-1,3-propanediol; 1,3-Butylene glycol; 1,3-Dihydroxybutane; Butane-1,3-diol; BD; 1,3-Butandiol; 1,3-Butylenglykol; 1,3-Butanodiol; Butanediol,1,3-; (RS)-1,3-Butanediol; Butylene glycol; NSC 402145; (±)-1,3-Butanediol, 99%
Linear Formula: CH3CH(OH)CH2CH2OH
CAS Number: 107-88-0
EC Number: 203-529-7
Molecular Weight: 90.12
Beilstein: 1731276
1,3-Butylene glycol is an organic compound with the formula CH3CH(OH)CH2CH2OH.
With two alcohol functional groups, the molecule is classified as a diol.
1,3-Butylene glycol is a colorless, water-soluble liquid.
1,3-Butylene glycol is one of four common structural isomers of butanediol.
INDUSTRIES
Pharma
Cleaning
Animal Nutrition
Coatings & Construction
Cosmetics
Rubber
Function
Humectant
Emollient
Stabilizer
Intermediate
Other
End-Use Industry
Cosmetics & Personal Care
Skin Care
Hair Care
Personal cleanliness
Bath & Shower
Others
Plastics & Polymers
Paint & Coating
Food
Others
1,3-Butylene glycol is an odorless, colorless, viscous liquid with a sweet flavor and bitter aftertaste.
1,3-Butylene glycol is used as an intermediate in manufacture of polyester plasticizers; humectant for cellophane, tobacco; and in the cosmetic and pharmaceutical industry as a glycerin substitute.1,3-Butanediol also has some mold inhibiting action.
1,3-Butylene glycol, also known as b-butylene glycol or BD, belongs to the class of organic compounds known as secondary alcohols.
Secondary alcohols are compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R’) (R,R’=alkyl, aryl).
1,3-Butylene glycolis a bitter and odorless tasting compound.
1,3-Butanediol has been detected, but not quantified, in several different foods, such as green bell peppers, orange bell peppers, pepper (c. annuum), red bell peppers, and yellow bell peppers.
This could make 1,3-Butylene glycola potential biomarker for the consumption of these foods.
A butanediol compound having two hydroxy groups in the 1- and 3-positions.
1,3-Butylene glycol is an organic chemical which belongs to the family of secondary alcohols.
At present, 1,3-butanediol is used mainly in surfactants, inks, solvents for natural and synthetic flavoring agents and serves as a co-monomer in manufacturing certain polyurethane and polyester resins.
1,3-Butanediol can also serve as a humectant to prevent loss of moisture in cosmetics, particularly in hair sprays and setting lotions.
1,3-Butanediol is also used as a humectant and emollient in personal care and cosmetic products, owing to its low toxicity, excellent hygroscopicity, and good water solubility.
Besides, 1,3-Butanediol is pharmaceutically involved in the production of colchicine derivatives as a anticancer agent and in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as a hypoglycaemic agent, which is effective for the treatment of diabetes.
1,3-Butanediol is a Solvent for flavouring agents 1,3-Butanediol is an organic chemical, an alcohol.
1,3-Butanediol is commonly used as a solvent for food flavouring agents and is a co-monomer used in certain polyurethane and polyester resins.
1,3-Butanediol is one of four stable isomers of butanediol.
In biology, 1,3-butanediol is used as a hypoglycaemic agent.
1,3-Butanediol is found in many foods, some of which are yellow bell pepper, red bell pepper, green bell pepper, and orange bell pepper.
1,3-Butanediol is used as an intermediate in the manufacture of polyester plasticizers; as a humectant for cellophane and tobacco; in polyurethanes and special polyester resins; in surface active agents; as a coupling agent; as a solvent; as a food additive and flavoring; in the cosmetics and pharmaceutical industries as a glycerin substitute; for deicing of aircraft;
1,3-Butanediol is Solvent, Monomer used in polyurethane and polyester resins, analytical reagent, substrate for organic synthesis
1,3-Butanediol (also known as 1,3-butylene glycol, butane-1,3-diol, or 1,3-dihydroxybutane) is an organic chemical, an alcohol. It is commonly used as a solvent for food flavouring agents and is a co-monomer used in certain polyurethane and polyester resins.
1,3-Butylene glycol is an important commercial chemical and it is widely used in personal care products and especially cosmetics like sunscreen, lotions and hair products.
1,3-Butylene glycol for Cosmetic has many applications in cosmetics and personal care products.
1,3-Butylene glycol for cosmetics can be used as a solvent and carrier to dissolve fragrance oils into water or alcohol solutions when formulating perfume concentrates or perfumed products that are applied on the skin.
1,3 butylene glycol is used as raw material for polyester plasticizers and unsaturated polyester resins humectant in cosmetics. The chemical is a viscosity decreasing component and prevents the dying out of cosmetics. The best characteristic of 1,3 butylene glycol is its ability to stabilize volatile compounds such as fragrances and flavors fixing them in cosmetic formulations and to reduce the loss of aroma. 1,3-BG also helps in the preservation of cosmetics against spoilage by micro-organisms. Firstly, it has a very good distribution coefficient, which leads to a better efficacy of preservatives mixed into formulation, thus making it possible to lower the dose of the applied preservative. Secondly, it has an antimicrobial effect, which helps arrest the growth of microorganisms in products.
Compared with glycerol, sorbitol, and propylene glycol, 1,3 butylene glycol is the most efficient polyol as antimicrobial agent.
1,3-Butanediol is alternative solvent to Propylene Glycol or Glycerol superior in technological and biological effects.
1,3-Butanediol is Viscosity decreasing.
As humectant, 1,3-Butanediol prevents the drying out of cosmetics.
1,3-Butanediol prevents the assimilation of water from atmospheres of high humidity into film-forming preparations.
1,3-Butanediol prevents crystallization of insolubles
1,3- ButaneDiol is also used as a food flavouring agent
Moreover, 1,3-butanediol is used to derive exceptional plasticizers such as monocarboxylic acid monoester.
These plasticizers are used in the production of plastics such as polyvinyl chloride (PVC).
Significant growth in plastic and polymer industries is anticipated to fuel the market in the coming years.
1,3-butanediol has applications as an antibacterial agent in dairy & meat products due to its antibacterial properties.
In terms of end-use industry, the market can be divided into cosmetics & personal care, polymer, paints & coatings, food, and others (including the plastic industry).
The cosmetics & personal care segment constituted a significant share of the global 1,3-butanediol market.
A rise in awareness about skin care and hair care and a rise in disposable income are anticipated to augment demand for cosmetics & personal care products.
1,3-butanediol has excellent properties for preservation of cosmetics against decay due to micro-organisms.
1,3-butanediol is extensively utilized in the formulation of skin care, hair care, and facemask cosmetic products.
In cosmetics,1,3-Butanediol can be used for lotion by mixing it with water; this mixture is known as an emulsion and will sometimes also contain other ingredients such as oils or glycerol for different purposes like skin protection.
In addition to providing hydration, butanediol has been found to have some anti-inflammatory properties which may help soothe irritated skin and potentially enhance barrier function in atopic dermatitis (eczema).
Face Cream :
The main use of butanediol is as a solvent.
It’s often used in face creams because it can penetrate the skin better than other solvents, and so helps to deliver more active ingredients.
However, its function varies depending on what cosmetics you’re using–it could be a moisturizer or cleansing agent for one product while acting as an emollient (softener) for another.
Chemical Properties
1,3-Butylene glycol has a sweet flavor with bitter aftertaste and is odorless when pure.
Chemical Properties
colourless liquid
Chemical Properties
Butylene glycol occurs as a clear, colorless, viscous liquid with a sweet flavor and bitter aftertaste.
Uses
1,3-Butanediol is used in the synthesis of colchicine derivatives as anticancer agents.
Also used in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as euglycem ic agents in the treatment of diabetes.
Uses
1,3-Butanediol’s most extensive use is as an intermediate in the manufacture of polyester plasticisers and other chemical products.
1,3-Butanediol finds some use as a solvent and humectant, a useful chemical intermediate.
1,3-Butanediol has extensive application in the manufacture of structural materials for boats, custom mouldings, and sheets and boards for construction applications.
1,3-Butanediol imparts resistance to weathering plus flexibility and impact resistance.
1,3-Butanediol is also used in the manufacture of saturated polyesters for polyurethane coatings, where the glycol imparts greater flexibility to the polyester molecule.
1,3-Butanediol is currently used in many personal care products. bio-Butylene Glycol is a natural diol, very pure, clear and odorless liquid. It is a common humectant used in cosmetic as moisturizer for the skin, solvent, fragrance enhancer.
Definition
ChEBI: A butanediol compound having two hydroxy groups in the 1- and 3-positions.
Production Methods
Butylene glycol is prepared by catalytic hydrogenation of aldol using Raney nickel.
Preparation
From formaldehyde and propylene via pressure and a catalyst.
Aroma threshold values
Detection: 70 to 100 ppm
Pharmaceutical Applications
1,3-Butanediol is used as a solvent and cosolvent for injectables.
1,3-Butanediol is used in topical ointments, creams, and lotions, and 1,3-Butanediol is also used as a vehicle in transdermal patches.
Butylene glycol is a good solvent for many pharmaceuticals, especially estrogenic substances.
In an oil-in-water emulsion, 1,3-Butanediol exerts its best antimicrobial effects at ～8% concentration.
Higher concentrations above 16.7% are required to inhibit fungal growth.
1,3-Butanediol is used as raw material for polyester plasticizers and unsaturated polyester resins humectant in cosmetics.
1,3-Butanediol is a viscosity decreasing component and prevents the dying out of cosmetics.
The best characteristic of 1,3-Butanediol is its ability to stabilize volatile compounds such as fragrances and flavors fixing them in cosmetic formulations and to reduce the loss of aroma.
1,3-Butanediol also helps in the preservation of cosmetics against spoilage by micro-organisms.
Firstly, 1,3-Butanediol has a very good distribution coefficient, which leads to a better efficacy of preservatives mixed into formulation, thus making it possible to lower the dose of the applied preservative.
Secondly, 1,3-Butanediol has an antimicrobial effect, which helps arrest the growth of microorganisms in products.
Compared with glycerol, sorbitol, and propylene glycol, 1,3-Butanediol is the most efficient polyol as antimicrobial agent.
(±)-1,3-Butanediol may be used as a solvent in the preparation of 6-methoxy-2-benzoxazolinone via condensation reaction between 2-hydroxy-4-methoxyphenyJarnmonium chloride and urea.
1,3-Butanediol can also react with carboxylic acids to form the corresponding chlorohydrin esters in the presence of chlorotrimethylsilane.
Other Applications of 1,3-Butanediol
1,3-Butanediol acts as a co-monomer in the production of polyurethane and polyester resins.
1,3-Butanediol is used as a humectant (to prevent loss of moisture) in cosmetics, especially in hair sprays and setting lotions.
1,3-Butanediol is used in surfactants, inks, solvents for natural and synthetic flavorings.
1,3-Butanediol is involved in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as euglycemic agents, which is used in the treatment of diabetes.
1,3-Butanediol (also known as 1,3-butylene glycol, butane-1,3-diol, or 1,3-dihydroxybutane) is a diol used as a chemical intermediate in the manufacture of polyester plasticizers and other products. It finds some use as a solvent for flavorings and as a humectant in pet foods, tobacco and cosmetics. It is one of four stable structural isomers of butanediol. In biology, 1,3-butanediol is used as a hypoglycaemic agent. 1,3-Butanediol can be converted into β-hydroxybutyrate and serve as a substrate for brain metabolism.
Notes
Hygroscopic. Air and moisture sensitive. Incompatible with strong oxidizing agents, acid chlorides, chloroformates and reducing agents. Keep container tightly closed in a dry and well-ventilated place.
Stability: Stable. Flammable. Hygroscopic – protect from air and moisture. Incompatible with strong oxidizing agents.
Butane-1,3-diol is a butanediol compound having two hydroxy groups in the 1- and 3-positions. It is a butanediol and a glycol.
1,3-Butanediol Practically insoluble in aliphatic hydrocarbons, benzene, toluene, carbon tetrachloride, ethanolamines, mineral and linseed oil; soluble in acetone, methyl ethyl ketone, ethanol, dibutyl phthalate, castor oil
Production and uses of 1,3-Butanediol
Hydrogenation of 3-hydroxybutanal gives 1,3-butanediol:
CH3CH(OH)CH2CHO + H2 → CH3CH(OH)CH2CH2OH
Dehydration of 1,3-butanediol gives 1,3-butadiene:
CH3CH(OH)CH2CH2OH → CH2=CH-CH=CH2 + 2 H2O
Occurrence
In biology, 1,3-butanediol is used as a hypoglycaemic agent.
1,3-Butanediol can be converted into β-hydroxybutyrate and serve as a substrate for brain metabolism.
Properties
Chemical formula: C4H10O2
Molar mass: 90.122 g·mol−1
Appearance: Colourless liquid
Density: 1.0053 g cm−3
Melting point: −50 °C (−58 °F; 223 K)
Boiling point: 204 to 210 °C; 399 to 410 °F; 477 to 483 K
Solubility in water: 1 kg dm−3
log P: −0.74
Vapor pressure: 8 Pa (at 20 °C)
Refractive index (nD): 1.44
Synonyms
Value Source
(RS)-1,3-Butandiol ChEBI
1,3 Butylene glycol ChEBI
1,3-Butandiol ChEBI
1,3-Butylene glycol ChEBI
1,3-Butylenglykol ChEBI
1,3-Dihydroxybutane ChEBI
1-Methyl-1,3-propanediol ChEBI
beta-Butylene glycol ChEBI
Methyltrimethylene glycol ChEBI
b-Butylene glycol Generator
Β-butylene glycol Generator
1,3-Butylene glycol, (14)C-labeled HMDB
1,3-Butylene glycol, (DL)-isomer HMDB
1,3-Butylene glycol, (R)-isomer HMDB
1,3-Butylene glycol, (S)-isomer HMDB
Butylene glycol HMDB
(+/-)-1,3-butanediol HMDB
(.+/-.)-1,3-butanediol HMDB
(R)-(-)-Butane-1,3-diol HMDB
(R)-1,3-Butanediol HMDB
(S)-(+)-1,3-Butanediol HMDB
(S)-(+)-Butane-1,3-diol HMDB
(S)-1,3-Butanediol HMDB
1,3-Butanodiol HMDB
BD HMDB
Butane-1,3-diol HMDB
DL-1,3-Butanediol HMDB
1,3-Butanediol
1,3-Butanediol
&β;-butylene glycol
(±)-1,3-Butanediol
(RS)-1,3-Butandiol
1,3-Butandiol [German]
1,3-Butanediol [French]
1,3-Butylene glycol
1,3-Butylenglykol [German]
1,3-Dihydroxybutane
107-88-0 [RN]
1731276 [Beilstein]
1-Methyl-1,3-propanediol
203-529-7 [EINECS]
Butane-1,3-diol
Butylene glycol
EK0440000
MFCD00004554 [MDL number]
QY1 & 2Q [WLN]
UNII:3XUS85K0RA
“1,3-BUTANEDIOL”|”BUTANE-1,3-DIOL”
“BUTANE-1,3-DIOL”
(±
(^+)-1,3-butanediol, 99%
(±)-1,3-Butanediol
(±)-1，3-butanediol
(±)-1,3-butanediol 99%
(±)-1,3-Butylene glycol
(±)-1,3-Butylene glycol
(ñ)-1,3-butanediol, 99%, extra pure
(R)-Butane-1,3-diol
(RS)-1,3-Butanediol
(S)-butane-1,3-diol
)-1,3-Butanediol
1,3 Butylene glycol
1,3-Butanediol 100 µg/mL in Acetonitrile
1,3-butanediol 99%
1,3-Butanodiol
1,3-Butylenglykol
BD
Butanediol,1,3-
Butylene Glycol (Butane-1,3-diol)
Contact allergens
This dihydric alcohol is used for its humectant and preservative potentiator properties in cosmetics, topical medicaments and polyurethane, polyester, cellophane, and cigarettes.
1,3-Butanediol has similar properties, but is less irritant than propylene glycol.
Contact allergies seem to be rare.
Safety Profile
Mdly toxic by ingestion and subcutaneous routes.
A skin and eye irritant.
Experimental reproductive effects.
Combustible when exposed to heat or flame. Incompatible with oxidizing materials.
To fight fire, use foam, alcohol foam, CO2, dry chemical.
When heated to decomposition it emits acrid smoke and irritating fumes.
Safety
1,3-Butanediol is used in a wide variety of cosmetic formulations and is generally regarded as a relatively nontoxic material.
1,3-Butanediol is mildly toxic by oral and subcutaneous routes.
In topical preparations, 1,3-Butanediol is regarded as minimally irritant.
1,3-Butanediol can cause allergic contact dermatitis, with local sensitivity reported in patch tests.
Some local irritation is produced on eye contact.
LD50 (guinea pig, oral): 11.0 g/kg
LD50 (mouse, oral): 12.98 g/kg
LD50 (rat, oral): 18.61 g/kg
LD50 (rat, SC): 20.0 g/kg
Carcinogenicity
There were no tumors found in the 2-year feeding studies on dogs and rats .
Thus, it appears that 1,3-butanediol is not carcinogenic.
Storage
Butylene glycol is hygroscopic and should be stored in a well-closed container in a cool, dry, well-ventilated place. When heated to decomposition, butylene glycol emits acrid smoke and irritating fumes.
Incompatibilities
Butylene glycol is incompatible with oxidizing reagents.
Regulatory Status
GRAS listed. Included in the FDA Inactive Ingredients Database (transdermal patches).
Included in licensed medicines in the UK (topical gel patches/medicated plasters).
1,3-Butanediol Preparation Products And Raw materials
Raw materials
PROPYLENE Butyraldehyde ALDOL
Preparation Products
Thermochemistry
Std molar entropy (So298): 227.2 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −501 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −2.5022 MJ mol−1
Hazards
GHS pictograms GHS07: Exclamation mark
GHS Signal word Warning
GHS hazard statements H319, H413
GHS precautionary statements P305+P351+P338
NFPA 704 (fire diamond)
NFPA 704 four-colored diamond
110
Flash point: 108 °C (226 °F; 381 K)
Autoignition temperature: 394 °C (741 °F; 667 K)
Related compounds
Related butanediol
1,2-Butanediol
1,4-Butanediol
2,3-Butanediol
Related compounds
2-Methylpentane
SYNONYMS:
1,3-BUTANEDIOL
Butane-1,3-diol
107-88-0
1,3-Butylene glycol
1,3-Dihydroxybutane
Methyltrimethylene glycol
beta-Butylene glycol
1,3 Butylene glycol
1,3-Butandiol
1-Methyl-1,3-propanediol
(RS)-1,3-Butandiol
(+/-)-1,3-Butanediol
1,3-Butylenglykol
1,3-Butanodiol
.beta.-Butylene glycol
BD
1,3-butane diol
NSC 402145
MFCD00004554
BUTANEDIOL,1,3-
NSC-402145
1,3-Butanediol, homopolymer
CHEBI:52683
NSC6966
1,3-butyleneglycol
DSSTox_CID_6773
DSSTox_RID_78210
DSSTox_GSID_26773
Caswell No. 128GG
Butane-1,3-diol (Butylene Glycol)
1,3-Butandiol [German]
55251-78-0
CAS-107-88-0
1,3-Butylenglykol [German]
HSDB 153
(+/-)-1,3-Butanediol, 99%, extra pure
r-(-)-1,3-butanediol
1,3-Butanediol, (R)-
1,3-Butanediol, (S)-
S-(+)-1,3-Butanediol
EINECS 203-529-7
BRN 1731276
(R)-(-)-1,3-Butylene Glycol
Aliphatic diol
AI3-11077
MFCD00064277
b-Butylene glycol
1.3-butanediol
1,3 -butanediol
DL-1,3-butanediol
Butylene glycol (NF)
ACMC-209gdj
(S)-(+)-butanediol
racemic 1,3-butanediol
BUTANEDIOL,3-
1,3-butanediol, DL-
(RS)-1,3-Butanediol
ACMC-1B2TP
( inverted exclamation markA)-1,3-Butanediol
EC 203-529-7
(+/-) 1,3 butandiol
(+/-)-1,3-butandiol
CC(O)CC[O]
0-01-00-00477 (Beilstein Handbook Reference)
ACMC-2097j5
(+/-)-1,3-Butylene glycol
(.+/-.)-1,3-Butanediol
CHEMBL3186475
DTXSID8026773
WLN: QY1 & 2Q
1,3-Butanediol, (.+/-.)-
NSC-6966
PRODUCTION OF 1,3-Butanediol
Acetaldol is prepared by acetaldehyde self-condensation in aqueous alkaline solutions.
Acetaldehyde conversion cannot be carried higher than 66.6% because aldol and acetaldehyde combine to yield 2,6-dimethyl-1,3-dioxan-4-ol.
The bound acetaldehyde is held so tenaciously that most commercial aldol is essentially equivalent to 2,6-dimethyl-1,3-dioxan-4-ol: Higher condensation products are often present.
It is difficult to decompose 2,6-dimethyl-1,3-dioxan-4-ol into aldol without simultaneously dehydrating it to crotonaldehyde.
Steam stripping is one of the most practical ways of removing the bound acetaldehyde.
Aldol is led directly to a hydrogenation system where it is reduced in the presence of Raney nickel or other catalysts.
Any of the acetaldehyde or 2,6-dimethyl-1,3-dioxan-4-ol left is reduced to ethanol and 2,4-dimethyl-1,3-dioxane, both of which are efficiency losses for the process.
Low-boilers are striped from the hydrogenated product and pure 1,3-butylene glycol is obtained by distillation under reduced pressure.
Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley and Sons, 1978-1984., p. V11 958 (1978)
Other Synonyms:
(3R)- butane-1,3-diol
(3R)-(-)- butane-1,3-diol
(R)- butane-1,3-diol
(R)-(-)- butane-1,3-diol
(3R)-1,3- butanediol
(R)-(-)-1,3- butanediol
(R)-1,3- butanediol
R-(-)-1,3- butanediol
1,3- butanediol, (3R)-
1,3- butanediol, (R)-
(R)-(-)-1,3- butylene glycol
(3R)-(-)-1,3- dihydroxybutane
• (±)-butane-1,3-diol
• 1,3-Butandiol
• Methyltrimethylene
• Methyltrimethylene glycol
• methyltrimethyleneglycol
• 1-METHYLTRIMETHYLENE GLYCOL
• 1,3-DIHYDROXYBUTANE
• (+/-)-1,3-BUTANEDIOL
• 1,3-BUTANEDIOL
• 1,3-BUTYLENE GLYCOL
• 1,3-BUTANEDIOL, REAGENTPLUS, 99%
• 1,3-BUTANEDIOL, ANHYDROUS, 99+%
• (q) -1,3-Butanediol 4 M Solution
• 1,3-BUTANEDIOL, 99+%
• 1,3Butanediol,98%
• 1,3-butan-diol (=1,3-butylene glycol)
• (n)-1,3-butanediol
• 1,3-butanediole
• 1,3-butylenglycol
• RS-1,3-BUTANEDIOL
• BUTAN-1,3-DIOL
• BUTYLENGLYKOL-1,3
• 1,3-BUTANEDIOL GR
• 1,3-BUTANEDIOL CP
• 1,3-BUTYLENE GLYCOL FCC
• Daicel 1,3-Butylene Glycol
• (+/-)-1,3-Butanediol ReagentPlus(R), 99.5%
• (+/-)-1,3-Butanediol Vetec(TM) reagent grade, 98%
• B-BUTYLENE GLYCOL
• (3S)-butane-1,3-diol
• 1,3-Butandiol Msynthplus
• 1,3-Butanediol, 99%, SuperDry, water≤30 ppm, J&KSeal
• 3-Butanediol
• 1,3-Butanodiol
• 1,3-butylene
• 1,3-Butylenglykol
• 1,3-Dihydroxybotane
• 1,3-Butaneiol
• 1-Methyl-1,3-propanediol
• BD
• beta-Butylene glycol
• beta-butyleneglycol
• butane-1,
• butane-1,3-
• Butane-1,3-diol
• 1,3-Butanediol [for BiocheMical Research]
• [for BiocheMical Research]
• 1,3-Butanediol
• (§1)-1,3-Butanediol, 99%, pure
• (§1)-1,3-Butanediol, pure, 99%
• 1,3-BUTANEDIOL FOR SYNTHESIS
• 1,3-Butylene Glycol 1,3-Dihydroxybutane
• ()-1,3-Butanediol, 99%, pure
• 1,3-Butanediol, 99%, SpcDry, Water≤50 ppM (by K.F.), SpcSeal
• 1,3-Butanediol, 99%, SpcDry, with Molecular sieves, Water≤50 ppM (by K.F.), SpcSeal
• (±)-1,3-Butanediol 4 M solution
• (±)-1,3-Butanediol solution
• Additive Screening Solution 03/Fluka kit no 78374
Immiscible with:
(E)-3-phenyl-2-propenal, 2,6,8-trimethyl-4-nonanone, 2,6-dimethyl-4-heptanone, 4-methoxybenzaldehyde, N,N-dipropylaniline, benzene, dibenzyl ether, dihexyl ether, ethyl (E)-3-phenylprop-2-enoate, ethyl phenylacetate, heptyl acetate
Partially miscible with:
diethyl ether
Miscible with:
1-amino-2-propanol, 1-phenylethan-1-amine, 1-tetradecanol, 2-(1-phenylethylamino)ethanol, 2-(2-hydroxyethyl-(1-phenylethyl)amino)ethanol, 2-ethoxyaniline, 2-ethylbutanoic acid, 2-methylphenol, 2-phenylethylamine, 3-heptanol, 3-methyl-2-butanone, 4-methylpentanoic acid, 5-ethyl-2-methylpyridine, N,N-diethylformamide, N-(2-aminoethyl)ethane-1,2-diamine, a-methylbenzyldimethylamine, dibutylamine, diisopropylamine, dipentylamine, ethanol, hexanenitrile, pyridine, salicylaldehyde, tributyl phosphate, trichloromethane, triethylenetetramine
With the rising trend of natural ingredients, manufacturers have introduced bio-based 1,3 butanediol derived from natural, plant-based sugar using fermentation process technology.
This innovative approach has a strong demand in cosmetic & personal care industry owing to the growing need for natural ingredients.
This bio-based technology helps in reducing global warming and carbon footprint.
Manufacturers have successfully commercialized their products in the market.
Segmentation Analysis of 1,3-Butandiol
Pharmaceutical Grade 1,3-Butandiol To Demonstrate Faster Growth
The pharmaceutical-grade category, under segmentation by product, is expected to showcase the higher CAGR in the 1,3-butylene glycol market during the forecast period.
This is majorly ascribed to the increasing adoption of the pharmaceutical grade in the cosmetic, personal care, and food industries. In recent years, common skin-related diseases, viz. acne, eczema, and seborrheic dermatitis, have increased in prevalence, due to stress, anxiety, alcohol and tobacco consumption, exposure to ultraviolet radiation, and pollution.
Considering such factors, the consumption of the pharmaceutical grade is expected to increase, owing to its usage as a humectant, for the prevention of moisture loss, as well as an emollient and stabilizer in skincare products.
Humectant Category To Generate Highest Revenue
The humectant category held the largest share, based on function, in 2019, and the trend is likely to continue in the 1,3-butylene glycol market.
The compound is vastly used as a humectant in cosmetic and personal care products, such as hair conditioners, body cleansers, facial creams, eye lotions, after-sun lotions, frizz serums, and lip balms.
Humectants have the ability to retain and lock the moisture, when applied on the skin, owing to which they are required in high volumes.
With the growth of the personal care and cosmetics sector across the globe, the consumption of the compound, as a humectant, is expected to increase, in turn, promoting the growth of the 1,3-butylene glycol market.
Cosmetics & Personal Care Products Application To Retain Its Dominance
In 2019, cosmetics and personal care products witnessed the highest consumption of the compound, and this category is expected to retain its dominance throughout the forecast period.
This is attributable to the increasing consumption of 1,3-butylene as a masking agent, humectant, skin conditioning agent, viscosity controller, and solvent, in cosmetic and personal care products.
With the growth of these end-use industries, the consumption of the compound is witnessing a rise, in turn, propelling the 1,3-butylene glycol market.