2-ETHYLHEXYL SALICYLATE
2-ETHYLHEXYL SALICYLATE
CAS NUMBER:118-60-5
EC NUMBER: 204-263-4
SYNONYMS: benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;2-ethyl hexyl 2-hydroxybenzoate;ethyl hexyl salicylate;ethylhexyl (octyl) salicylate;2-ethylhexyl 2-hydroxybenzoate;2-ethylhexyl salicylate;filtrosol C;2-hydroxybenzoic acid 2-ethyl hexyl ester; megasol-complex (Vevy);neo heliopan OS (Symrise);octisalate;octyl salicylate;2-octyl salicylate;salicylic acid 2-ethyl hexyl ester;salicylic acid 2-ethylhexyl ester;salicylic acid, 2-ethylhexyl ester;salotan;sunarome;sunarome O;YOSE;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; Salicylic acid, 2-ethylhexyl ester; Sunarome O; Sunarome WMO; USAF DO-11; WMO; Dermoblock OS; Escalol 587; Ethylhexyl salicylate; Neo Heliopan OS; Octyl salicylate; Uvinul O-18; 2-Ethylhexyl 2-hydroxybenzoate; NSC 46151; Octisalate; 194304-34-2; 8014-40-2; 204-263-4;WMO;usafdo-11;USAF do-11;Sunarome O;EUSOLEXOS;OCTISALATE;Escalol 587;Uvinul O-18;Sunarome WMO;Dermoblock OS;2-hydroxy-benzoicaci2-ethylhexylester;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;Benzoicacid,2-hydroxy-,2ethylhexylester; Dermoblock OS;Escalol 587;Ethylhexyl salicylate;NeoHeliopan OS;piedmonti,2-ethvlhexvlsavlate;trans-2-Hexenyl salicylate;Salicylic acid 2-ethylhexylester;Octylsalicylate;Ethyl hexyl salicylate;OCTISALic acid;Octyl salicylic acid;Uvinul;Octyl salicylate;Salicylic Acid 2-Ethylhexyl Ester,Octyl Salicylate, Salicylic Acid Octyl Ester;Octisalate, Octyl salicylate;2-ethylhexyl 2-hydroxybenzoate;ETHYLHEXYLSALICYLATE, 2-ETHYLHEXYL 2-HYDROXYBENZOATE; 2-ETHYLHEXYL ESTER BENZOIC ACID, 2-HYDROXY-; 2-ETHYLHEXYL ESTER SALICYLICACID; 2-ETHYLHEXYL SALICYLATE; 2-HYDROXY- 2-ETHYLHEXYL ESTER BENZOIC ACID; 3-10-00-00124 (BEILSTEIN HANDBOOK REFERENCE) ;BENZOIC ACID, 2-HYDROXY-, 2-ETHYLHEXYL ESTER; BENZOIC ACID, 2HYDROXY, 2ETHYLHEXYL ESTER; BRN 2730664; EHS; EINECS 2042634;2-Ethylhexyl o-Hydroxybenzoate; Dermoblock OS; Escalol 587; Eusolex OS; HallBrite OS-USP; NSC 46151; Neo Heliopan OS;Octisalate; Octyl Salicylate; Parsol EHS; 2-Ethylhexyl Ester Salicylic Acid; Solarom OS; Sunarome O; Sunarome WMO; Uvinul0-18; WMO;2-hydroxy-benzoicaci2-ethylhexylester;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;Benzoicacid,2-hydroxy-,2-ethylhexylester;Dermoblock OS;Escalol 587;Ethylhexyl salicylate;Neo Heliopan OS;piedmonti,2-ethvlhexvlsavlate; 2-Ethylhexyl salicylate;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;Sunarome O;Sunarome WMO;USAF do-11;WMO;Dermoblock OS;Escalol 587;Ethylhexyl salicylate;Neo Heliopan OS;Octyl salicylate;Uvinul O-18;Parsol EHS;Salicylic acid, 2-ethylhexylester;Solarom OS;Sunarome O;Sunarome WMO;Uvinul 0-18;2-Ethylhexylo-hydroxybenzoate;Dermoblock OS;Escalol 587;EusolexOS;NSC46151;Neo Heliopan OS;Octisalate;Octyl salicylate;2-etilhegzilsalisilat; 2- etil hegzil salisilat, 2-etil hegzilsalisilat;2etihegzilsalisilat; 2 etilhegzilsalisilat; 2 etil hegzil salisilat;2ETLHEGZLSALSLAT; 2-ETLHEGZLSAKSLAT; 2 ETL HEGZL SALSLAT; 2 ETL HEGZLSALSLAT; 2 ETLHEGZLSALSLAT; 2- ETL HEGZL SALSLAT, 2- ETL HEGZLSALSLAT;
2-Ethylhexyl salicylate could be commonly used in cosmetics and sunscreens acting as a skin penetration enhancer and could absorb UVB rays at some extent. Ethylhexyl salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of a salicylic acid with 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor.This compound belongs to the class of organic compounds known as o-hydroxybenzoic acid esters. These are benzoic acid esters where the benzene ring is ortho-substituted with a hydroxy group.Has a light orchid-like aroma but is mainly used in fragrances to improve UV stability, reducing colour and odour changes due to light exposure.2-Ethylhexyl is manufactured and/or imported in the European Economic Area in 1 000 – 10 000 tonnes per year.2-Ethylhexyl salicylate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.2-Ethylhexyl salicylate, an ultraviolet filter, is widely used to protect skin against sunlight-induced harmful effects in the cosmetic industry. In this study, the green synthesis of 2-ethylhexyl salicylate using immobilized lipase through a solvent-free and reduced pressure evaporation system was investigated. A Box-Behnken design was employed to develop an artificial neural network (ANN) model. The parameters for an optimal architecture of an ANN were set out: a quick propagation algorithm, a hyperbolic tangent transfer function, 10,000 iterations, and six nodes within the hidden layer. The best-fitting performance of the ANN was determined by the coefficient of determination and the root-mean-square error between the correlation of predicted and experimental data, indicating that the ANN displayed excellent data-fitting properties. Finally, the experimental conditions of synthesis were well established with the optimal parameters to obtain a high conversion of 2-ethylhexyl salicylate. In conclusion, this study efficiently replaces the traditional solvents with a green process for the synthesis of 2-ethylhexyl salicylate to avoid environmental contamination, and this process is well-modeled by a methodological ANN for optimization, which might be a benefit for industrial production.Absorption and excited state intramolecular proton transfer (ESIPT) fluorescence of 2′-ethylhexyl salicylate (EHS) were examined in the presence of cationic, non-ionic, and anionic surfactants. It was found that linear 2-ethylhexyl salicylate molecule was solubilized in micelles with its flexible and hydrophobic 2′-ethylhexyl chain toward the micellar core and with its rigid salicyl moiety toward the micelle-water interface. The UV absorption of EHS was improved and the intramolecular hydrogen bonding formation of 2-ethylhexyl salicylate was favored, resulting in greatly enhanced ESIPT fluorescence. The excited 2-ethylhexyl salicylate molecules decay via visible luminescence and non-radiative deactivation. The binding sites of 2-ethylhexyl salicylate in micelles were explained at a molecular level in terms of molecular structures and sizes of EHS and surfactants. Dynamic fluorescence quenching and spectral measurements of ester hydrolysis of 2-ethylhexyl salicylate provide further evidences for the binding sites of 2-ethylhexyl salicylate in different micelles.
Consumer Uses
2-Ethylhexyl salicylate i salicylates used in the following products: cosmetics and personal care products and perfumes and fragrances. Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Article service life
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
This substance is used in the following products: cosmetics and personal care products. ECHA has no public registered data on the types of manufacture using this substance. Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Formulation or re-packing
2-Ethylhexyl salicylate is used in the following products: cosmetics and personal care products, welding & soldering products and perfumes and fragrances. Release to the environment of this substance can occur from industrial use: formulation of mixtures.
Uses at industrial sites
2-Ethylhexyl salicylate is used in the following products: cosmetics and personal care products. 2-Ethylhexyl is used for the manufacture of: chemicals. Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites.
Manufacture
Release to the environment of this substance can occur from industrial use: manufacturing of the substance.
2-Etilheksil salisilat, kozmetikte ve cilt penetrasyon arttrc olarak etkiyen güne koruyucularnda yaygn olarak kullanlabilir ve UVB nlarn bir miktar emer. Etilheksil salisilat veya oktil salisilat, bir bileen olarak kullanlan organik bir bileiktir.Güneten koruyucular ve kozmetikler güneten UVB (ultraviyole) nlarn emer. Younlamann oluturduu bir esterdir.2-etilheksanol ile salisilik asit. Hafif çiçek kokulu renksiz yal bir svdr.O-hidroksibenzoik asit esterleri olarak bilinen organik bileiklerin snf. Bunlar benzen halkasnn bulunduu benzoik asit esterleridir. bir hidroksi grubu ile orto ikamelidir. Hafif bir orkide benzeri aromas vardr fakat esas olarak UV’yi iyiletirmek için kokularda kullanlr.Stabilite, a bal olarak renk ve koku deiikliklerini azaltr.2-Etilheksil üretilir ve / veya ithal edilir.Ylda 1 000 – 10 000 ton arasnda Avrupa Ekonomik Alan.2-Etilheksil salisilat tüketiciler tarafndan profesyonel olarak kullanlmaktadr.çiler (yaygn kullanmlar), formülasyonlarda veya yeniden ambalajlamada, sanayi tesislerinde ve imalatta, 2-Etilheksil salisilat,bir ultraviyole filtre, kozmetik endüstrisinde güne na bal zararl etkilere kar cildi korumak için yaygn olarak kullanlr.Bu çalmada, 2-etilheksil salisilatn immobilize lipaz kullanlarak solventsiz ve indirgenerek yeil senteziBasnçl buharlama sistemi aratrld. Yapay sinir an gelitirmek için bir kutu-Behnken tasarm kullanld.(YSA) modeli. Bir ANN’nin optimal mimarisi için parametreler belirlendi: hzl bir yaylma algoritmas, bir Gizli katmandaki hiperbolik teet transfer fonksiyonu, 10.000 yineleme ve alt düüm. En uygun YSA’nn performans, belirleme katsays ve ortalama-karekök hatas arasnda belirlendi.Tahmin edilen ve deneysel verilerin korelasyonu, ANN’nin mükemmel veri uydurma özellikleri gösterdiini gösterir.Son olarak, yüksek bir sentez elde etmek için en uygun parametrelerle deneysel sentez koullar salanmtr.2-etilheksil salisilatn dönütürülmesi. Sonuç olarak, bu çalma, geleneksel çözücülerinÇevresel kontaminasyonu önlemek için 2-etilheksil salisilat sentezi için yeil bir süreç ve bu süreçendüstriyel üretim için bir faydas olabilecek, optimizasyon için metodolojik bir ANN ile iyi modellenmitir. 2′-etilheksil salisilatn (EHS) absorbsiyon ve uyarlm durum moleküler proton transferi (ESIPT) floresans, iyonik olmayan katyonik varlnda incelenmitir. ve anyonik sürfaktanlar. Lineer 2- etilheksil salisilat molekülünün, misellerde, esnek ve hidrofobik 2p-etilheksil zinciri, misel çekirdee doru ve kat salisil ksm ile misel-su ara yüzeyine doru çözündürülmütür. EHS’nin UV emilimi iyiletirildi ve 2-etilheksil salisilatn moleküler hidrojen balama formasyonu tercih edildi ve ESIPT floresans artt. Uyarlm EHS molekülleri, görünür parlaklk ve radyal olmayan deaktivasyon yoluyla bozulur. 2-Etilheksil salisilatn misellerde balanma yerleri, moleküler yaplar ve EHS ve yüzey aktif cisimlerinin boyutlar bakmndan bir moleküler seviyede açklanmtr. Dinamik floresan söndürme ve 2-etilheksil salisilatn ester hidrolizinin spektral ölçümleri, farkl misellerde 2-etilheksil salisilatn balanma bölgeleri için baka kantlar salar.
Tüketici Kullanmlar
Aadaki ürünlerde kullanlan 2-Etilheksil salisilat i salisilatlar: kozmetik ve kiisel bakm ürünleri ve parfümler ve kokular. Bu maddenin çevreye dier salmlar aadakilerden kaynaklanyor olabilir: ileme yardmcs olarak iç mekan kullanm ve ileme yardmcs olarak d mekan kullanm.
Makale hizmet ömrü
ECHA’nn, bu maddenin çevreye salnmasnn en muhtemel olduu yollarla ilgili halka açk bir veri bulunmamaktadr. ECHA’nn, maddenin hangi maddelere ilenip ilenmeyeceini belirten halka açk hiçbir kayd bulunmamaktadr.
Profesyonel çalanlarn yaygn kullanm
Bu madde aadaki ürünlerde kullanlr: kozmetik ve kiisel bakm ürünleri. ECHA’nn herkese açk kaytl bir veri yok. Bu maddeyi kullanarak üretim türlerine. Bu maddenin çevreye dier salnm gerçekleebilir from: ileme yardm olarak iç mekan kullanm ve ileme yardm olarak d mekan kullanm.
Formülasyon veya yeniden paketleme
2-Etilheksil salisilat aadaki ürünlerde kullanlr: kozmetik ve kiisel bakm ürünleri, kaynak ve lehimleme ürünler, parfümler ve kokular. Bu maddenin çevreye braklmas endüstriyel kullanmdan kaynaklanabilir:karmlarn formülasyonu.
Sanayi sitelerinde kullanr
2-Etilheksil salisilat aadaki ürünlerde kullanlr: kozmetik ve kiisel bakm ürünleri. 2-Etilheksil için kullanlr.