C 12 14 ALCOHOL 7 EO
c 12 14 alcohol 7 eo
CAS Number 68439-50-9
synonyms:
c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c1214 7eo; c12-14 alkol 7 eo; c 14_12 alcohol 7 eo; c12/14alcohol7eo; C 12/14 alkohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcool; alcohol c 12 14 7 eo; alkol c 12 14 7Eo; c12-14 Alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; Alcohols, C12-14(even numbered), ethoxylated ; Lauryl Alcohol Ethoxylate; Sodium Laureth Sulfate;Alcohols; C12-14; ethoxylated; FATTYALCOHOL(C12-C14)POLYGLYCOL(3OEO)ETHER; POLYALKOXYLATEDALIPHATICALCOHOL; Alcohol-(C12-C14), ethoxylated; Ethoxylated alcohols (C12-14); C12-14 Fatty alcohols ethoxylated; c 12 14 alcohol 7 eo;c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c1214 7eo; c12-14 alkol 7 eo; c 14_12 alcohol 7 eo; c12/14alcohol7eo; C 12/14 alkohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcool; alcohol c 12 14 7 eo; alkol c 12 14 7Eo; c12-14 Alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c 12-14 alcohol 7 eo; c12-14 alcohol 7eo; c 12/14 alcohol 7 eo; C -12-14 alkol 7 eo; 7 eo c 12-14 alcohol; alcohol c 12-14 7 eo; alkol c 12-14 7eo; C12 alkol; c1214 alkol; c14 alkol; C12-14 AE7; C12-14 A E7; C12-14 A E 7; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c1214 7eo; c12-14 alkol 7 eo; c 14_12 alcohol 7 eo; c12/14alcohol7eo; C 12/14 alkohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcool; alcohol c 12 14 7 eo; alkol c 12 14 7Eo; c12-14 Alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; c 12 14 alcohol 7 eo; c1214 alcohol 7eo; c 12-14 alcohol 7 eo; C 12-14 alkol 7 eo; 7 eo c 12 14 alcohol; alcohol c 12 14 7 eo; alkol c 12 14 7eo; c12-14 alkol 7eo; c 14-12 alcohol 7 eo; c 12/14 alcohol 7 eo; C 12/14 alcohol 7 EO; C 12-14 alkol 7eo; Alcohols, C12-14(even numbered), ethoxylated ; Lauryl Alcohol Ethoxylate; Sodium Laureth Sulfate;Alcohols; C12-14; ethoxylated; FATTYALCOHOL(C12-C14)POLYGLYCOL(3OEO)ETHER; POLYALKOXYLATEDALIPHATICALCOHOL; Alcohol-(C12-C14), ethoxylated; Ethoxylated alcohols (C12-14); C12-14 Fatty alcohols ethoxylated
C 12 14 alcohol 7 eo
Alcohols, C12-14, ethoxylated
1 – 2.5 moles ethoxylated
Regulatory process names 1 IUPAC names 30 Trade names 377 Other identifiers 25
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Substance identity
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EC / List no.: 500-213-3
CAS no.: 68439-50-9
Mol. formula: (C2H4O)1-3(CH2)10-12C2H6O
formula
Hazard classification & labelling
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Warning! According to the classification provided by companies to ECHA in REACH registrations C 12 14 alcohol 7 eo is very toxic to aquatic life and is harmful to aquatic life with long lasting effects.
About C 12 14 alcohol 7 eo
Helpful information
C 12 14 alcohol 7 eo is manufactured and/or imported in the European Economic Area in 100 000 – 1 000 000 tonnes per year.
C 12 14 alcohol 7 eo is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
C 12 14 alcohol 7 eo is used in the following products: washing & cleaning products, plant protection products, fertilisers, lubricants and greases, air care products and fuels.
Other release to the environment of C 12 14 alcohol 7 eo is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Article service life
ECHA has no public registered data on the routes by which C 12 14 alcohol 7 eo is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.
Widespread uses by professional workers
C 12 14 alcohol 7 eo is used in the following products: washing & cleaning products and polishes and waxes.
C 12 14 alcohol 7 eo is used in the following areas: formulation of mixtures and/or re-packaging, municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and health services.
C 12 14 alcohol 7 eo is used for the manufacture of: chemicals.
Other release to the environment of C 12 14 alcohol 7 eo is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Formulation or re-packing
C 12 14 alcohol 7 eo is used in the following products: washing & cleaning products, lubricants and greases, metal working fluids, fertilisers and cosmetics and personal care products.
Release to the environment of C 12 14 alcohol 7 eo can occur from industrial use: formulation of mixtures, in processing aids at industrial sites and formulation in materials.
Uses at industrial sites
C 12 14 alcohol 7 eo is used in the following products: washing & cleaning products, metal surface treatment products, lubricants and greases and metal working fluids.
C 12 14 alcohol 7 eo is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
C 12 14 alcohol 7 eo is used for the manufacture of: chemicals, machinery and vehicles and fabricated metal products.
Release to the environment of C 12 14 alcohol 7 eo can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release and formulation of mixtures.
Manufacture of C 12 14 alcohol 7 eo
Release to the environment of C 12 14 alcohol 7 eo can occur from industrial use: manufacturing of the substance.
How to use C 12 14 alcohol 7 eo safely
Help
ECHA has no data from registration dossiers on the precautionary measures for using C 12 14 alcohol 7 eo.
Guidance on the safe use of the substance provided by manufacturers and importers of C 12 14 alcohol 7 eo.
C 12 14 7 EO non-ionic surfactant. Latronol L 7 is a colorless and odorless liquid and efficient (O/W) oil in water emulsifier. It is also biodegradable. Can be used in homecare, textile, paintings/coatings and agricultural applications.
C12-14 Alcohol Ethoxylates (7EO) (C12-14
AE7)
oleochemical non-ionic surfactant
Substance Identification
IUPAC Name Alcohols, C12-14(even
numbered), ethoxylated CAS Number 68439-50-9
Other Names Lauryl Alcohol Ethoxylate
Molecular Formula of C 12 14 alcohol 7 eo
UVCB substance (substances
of Unknown or Variable
composition, Complex
reaction products or
Biological materials), no
univocal molecular formula
available
Structural formula of C 12 14 alcohol 7 eo:
Physical/Chemical Properties of C 12 14 alcohol 7 eo [1,2]
Molecular Weight of C 12 14 alcohol 7 eo 494.70 -522.75 g/mol
Physical state of C 12 14 alcohol 7 eo: Liquid
Appearance of C 12 14 alcohol 7 eo Colourless, homogenous and opaque
Odour of C 12 14 alcohol 7 eo Slight characteristic
Density of C 12 14 alcohol 7 eo 0.9 g/cm³ at 20 °C (proxy from C12-14 AE2)
Melting Points of C 12 14 alcohol 7 eo 25 – 35 °C
Boiling point of C 12 14 alcohol 7 eo 266.95 °C at 101.4 kPa (proxy from C12-14 AE2)
Flash Point of C 12 14 alcohol 7 eo 149 °C at 101.4 kPa (proxy from C 12 14 alcohol 7 eo , ethoxylated (1-2.5 EO))
Vapour Pressure of C 12 14 alcohol 7 eo 0.014 – 0.11 Pa at 25°C
Water Solubility C 12 14 alcohol 7 eo 15 mg/l at 25°C
Flammability C 12 14 alcohol 7 eo No data available
Explosive Properties C 12 14 alcohol 7 eo No data available
Surface Tension C 12 14 alcohol 7 eo C 12 14 alcohol 7 eo 27 mN/m at 20°C (proxy from C12-14 AE2)
Octanol/water
Partition coefficient
(Kow)
log KOW = 4.63 – 5.71
Product and Process
Description
C 12 14 alcohol 7 eo is a non-ionic surfactant, belonging to the group of alcohol ethoxylates, with 7 moles of
ethylene oxide. The alcohol ethoxylates with seven ethylene oxide units are produced by the reaction
of C12-C14 fatty alcohols (oleo) with ethylene oxide. The addition of ethylene oxide to C12-14 fatty
alcohols leads to a distribution of homologue polyethylene glycol ether groups.
The ethoxylation reaction can be catalyzed by alkaline catalysts as e.g. potassium hydroxide or by
acidic catalysts as e.g. boron trifluoride or zinc chloride. For detergent range alcohol ethoxylates, the
alkaline catalysis is normally used.
The intermediate ethylene oxide is industrially produced by direct oxidation of ethylene in the
presence of silver catalyst (Further details of the ethylene oxide production are explained in the Eco
Date: 02/06/2017
2
Profile fact sheet of the precursor ethylene oxide (#8)).
Application
Personal Care: Foaming Agent in Shampoos and Bath Gels.
Detergents: Wetting Agent in Detergents, Laundry Pre-spotters and Hard Surface Cleaners
Surfactants and Esters: Surfactant Intermediate, Sulfonated to Make SLES (Sodium Lauryl Ether
Sulfate). Used both in household and industrial products.
Textiles: Wetting Agent in Textile and Leather Processing.
Life cycle Assessment
General Introduction
These Environmental Fact Sheets are a product of the ERASM Surfactant Life Cycle & Ecofootprinting (SLE) project. The
objective of this project was to establish or update the current environmental profile of 15 surfactants and 17 precursors, taking
into consideration actual surfactant production technology and consistent high quality background data.
The Eco-profiles are based upon life cycle assessment (LCA) and have been prepared in accordance with the ISO standard [ISO
14040: 2006 and ISO 14044: 2006]. In addition, the project follows the ILCD (2010) handbook. This Fact Sheet describes the
cradle-to-gate production for C 12 14 alcohol 7 eo. C 12 14 alcohol 7 eo is a petrochemical surfactant.
The ERASM SLE project recommends to use the data provided in a full ‘cradle-to-grave’ life cycle context of the surfactant in a
real application.
Further information on the ERASM SLE project and the source of these datasets can be found in [3].
The full LCI can be accessed via www.erasm.org or via http://lcdn.thinkstep.com/Node/
Goal and Scope of ERASM SLE Project [3]
The main goal was to update the existing LCI inventories [4,6] for the production of C 12 14 alcohol 7 eo and its main
precursors/intermediates.
Temporal Coverage
Data collected represents a 12 month averages of C 12 14 alcohol 7 eo production in the year 2011, to
compensate seasonal influence of data. The dataset is considered to be valid until substantial
technological changes in the production chain occur.
Geographical Coverage Current data were based on three suppliers representing C 12 14 alcohol 7 eo production in Europe.
The geographical representativeness for C 12 14 alcohol 7 eo was considered ‘good’
Technological
Coverage
The technological representativeness for C 12 14 alcohol 7 eo was considered ‘good’.
Figure 1 provides a schematic overview of the production process of C 12 14 alcohol 7 eo.
Representativeness for
market volume >60% (Represented market volume (in mass) covered by primary data used in ERASM SLE project)
Declared Unit
In ERASM SLE project the declared unit (functional unit) and reference flow is one thousand kilogram
(1000 kg) of surfactant active ingredient. This was the reference unit also used in [4].
Functional Unit: 1 metric tonne of C 12 14 alcohol 7 eo 100% active substance.
Cradle-to Gate System
Boundaries
Included Excluded
Fatty alcohol C12-14 (oleo) production (this
production is further explained in the Eco-Profile
fact sheet of the precursor C12-14 fatty alcohol
(#3))
Construction of major capital equipment
(Infrastructure)
Ethylene oxide production( this production is
further explained in the Eco-Profile fact sheet of
the precursor ethylene oxide (#8))
Maintenance and operation of support
equipment
Energy production Human labor and employee transport
Utilities Packaging
Transportation processes for the main materials
Date: 02/06/2017
3
Water use and treatment of waste water
Treatment of wastes
Assumptions and
Limitations
Transportation was only considered for the main materials (covers about 95% of the mass of all
inputs), other transportation was not considered.
Cut-off Criteria [5]
No significant cut-offs were used.
The LCI study included all material inputs that had a cumulative total (refers to unit process level) of at
least 98% of the total mass inputs to the unit process, and included all material inputs that had a
cumulative total of at least 98% of total energy inputs to the unit process.
The study included any material that had environmental significance in its extraction, manufacture,
use or disposal, is highly toxic, dangerous for the environment, or is classified as hazardous waste.
The sum of the excluded material flows did not exceed 5% of mass, energy or environmental
relevance.
Calculation Rules
Allocation
For C 12 14 alcohol 7 eo production, allocation was not applied to the foreground system.
However, allocation was applied for some background data (mass allocation for the
renewable precursors PKO and CNO).
Aggregated
data
Vertical averaging was considered (as long as the final product was the same, different
processes with common product intermediates can be aggregated in the average)
Life Cycle Inventory and Impact Assessment [3]
Based on the LCI data an environmental impact assessment was performed for the indicators Primary Energy Demand (PED) and
Global Warming Potential (GWP). Other impacts may be calculated from the full LCI dataset.
Primary Energy Demand (PED): An analysis of the inventory data showed that the main contribution comes from the main raw
materials C12-14 fatty alcohol and ethylene oxide (together about 90% contributions). Electricity and thermal energy
generation each cause 3-5% of the PED. Direct process emissions, other chemicals, utilities, process waste treatment, and
transport do not have relevant influence (each smaller 0.5%). The alcohol ethoxylates based on fatty alcohols from natural
sources have a lower primary energy demand compared to those based on petrochemical feedstock.
Global Warming Potential (GWP): An analysis of the inventory data showed that the main contribution comes from the main
raw materials C12-14 fatty alcohol and ethylene oxide (together about 90% contributions). Electricity and thermal energy
generation each cause 3-5% of the GWP. Direct process emissions, other chemicals, utilities, process waste treatment, and
transport do not have relevant influence (each smaller 0.5%).
The high value for carbon uptake of the C12-C14 alcohol ethoxylate is due to the main precursor C 12 14 alcohol 7 eo based on
palm kernel oil and coconut oil.
As C 12 14 alcohol 7 eo has a lower GWP than the alcohol, a higher share of C 12 14 alcohol 7 eo in C 12 14 alcohol 7 eo results in a lower GWP than for C12-14 AE3.
The alcohol ethoxylates based on fatty alcohols from natural sources have a lower global warming potential compared to those
based on petrochemical feedstock
C 12 14 alcohol 7 eo is a non-ionic surfactant, belonging to the group of alcohol ethoxylates, with 7 moles of ethylene oxide. The alcohol ethoxylates with seven ethylene oxide units are produced by the reaction of C12-C14 fatty alcohols (oleo) with ethylene oxide. The addition of ethylene oxide to C12-14 fatty alcohols leads to a distribution of homologue polyethylene glycol ether groups.
The ethoxylation reaction can be catalyzed by alkaline catalysts as e.g. potassium hydroxide or by acidic catalysts as e.g. boron trifluoride or zinc chloride. For detergent range alcohol ethoxylates, the alkaline catalysis is normally used.
The intermediate ethylene oxide is industrially produced by direct oxidation of ethylene in the presence of silver catalyst (Further details of the ethylene oxide production are explained in the Eco Profile fact sheet of the precursor ethylene oxide.
Applications of C 12 14 alcohol 7 eo
Personal Care: Foaming Agent in Shampoos and Bath Gels.
Detergents: Wetting Agent in Detergents, Laundry Pre-spotters and Hard Surface Cleaners
Surfactants and Esters: Surfactant Intermediate, Sulfonated to Make SLES (Sodium Lauryl Ether Sulfate). Used both in household and industrial products.
Textiles: Wetting Agent in Textile and Leather Processing.
These Environmental Fact Sheets are a product of the ERASM Surfactant Life Cycle & Ecofootprinting (SLE) project. The
objective of this project was to establish or update the current environmental profile of 15 surfactants and 17 precursors, taking
into consideration actual surfactant production technology and consistent high quality background data.
The Eco-profiles are based upon life cycle assessment (LCA) and have been prepared in accordance with the ISO standard [ISO
14040: 2006 and ISO 14044: 2006]. In addition, the project follows the ILCD (2010) handbook. This Fact Sheet describes the
cradle-to-gate production for C 12 14 alcohol 7 eo. C 12 14 alcohol 7 eo is a petrochemical surfactant.
The ERASM SLE project recommends to use the data provided in a full ‘cradle-to-grave’ life cycle context of the surfactant in a
real application.
Further information on the ERASM SLE project and the source of these datasets can be found in
Based on the LCI data an environmental impact assessment was performed for the indicators Primary Energy Demand (PED) and
Global Warming Potential (GWP). Other impacts may be calculated from the full LCI dataset.
Primary Energy Demand (PED): An analysis of the inventory data showed that the main contribution comes from the main raw
materials C 12 14 alcohol 7 eo and ethylene oxide (together about 90% contributions). Electricity and thermal energy
generation each cause 3-5% of the PED. Direct process emissions, other chemicals, utilities, process waste treatment, and
transport do not have relevant influence (each smaller 0.5%). The alcohol ethoxylates based on fatty alcohols from natural
sources have a lower primary energy demand compared to those based on petrochemical feedstock.
Global Warming Potential (GWP): An analysis of the inventory data showed that the main contribution comes from the main
raw materials C 12 14 alcohol 7 eo and ethylene oxide (together about 90% contributions). Electricity and thermal energy
generation each cause 3-5% of the GWP. Direct process emissions, other chemicals, utilities, process waste treatment, and
transport do not have relevant influence (each smaller 0.5%).
The high value for carbon uptake of the C12-C14 alcohol ethoxylate is due to the main precursor C 12 14 alcohol 7 eo based on
palm kernel oil and coconut oil.
As EO has a lower GWP than the alcohol, a higher share of EO in C 12 14 alcohol 7 eo results in a lower GWP than for C12-14 AE3.
The alcohol ethoxylates based on fatty alcohols from natural sources have a lower global warming potential compared to those
based on petrochemical feedstock.
Application
Laundry powders
Laundry tablets
Laundry liquids
Pretreatmen agents
All purpose cleaners
Bathroom cleaners
Sanitary cleaners
Dishwashing liquids
Janitorial products
Vehicle cleaners
Shampoos
Shower gels
Cosmetic cleaning emulsions
Auxiliaries for texlile production and leather processing
Emulsions for technical processes
Sodium lauryl ether sulfate based on fatty alcohol ethoxylate C12-14 with 7 moles of EO
appearance at 20°C clear yellowish liquid
density at 20°C, g/cm3, c. 1.05
solids, % wt. 27 ± 1
sodium sulfate, % wt., max. 0.8
pH, 10% aqueous solution 7.0 – 8.5
C 12 14 alcohol 7 eo consumption by adult women is consistently associated with risk of breast cancer. Several questions regarding alcohol and breast cancer need to be addressed. Menarche to first pregnancy represents a window of time when breast tissue is particularly susceptible to carcinogens. Youth alcohol consumption is common in the USA, largely in the form of binge drinking and heavy drinking. Whether alcohol intake acts early in the process of breast tumorigenesis is unclear. This review aims to focus on the influences of timing and patterns of alcohol consumption and the effect of C 12 14 alcohol 7 eo on intermediate risk markers. We also review possible mechanisms underlying the alcohol-breast cancer association.
C 12 14 alcohol 7 eol is considered by the International Agency for Research on Cancer to be causally related to breast cancer risk [1], with a 7-10% increase in risk for each 10 g (~1 drink) alcohol consumed daily by adult women [2-4]. This association is observed in both premenopausal and postmenopausal women. Compared with other organs, breast appears to be more susceptible to carcinogenic effects of alcohol. The risk of breast cancer is significantly increased by 4-15% for light alcohol consumption (?1 drink/day or ?12.5 g/day) [2,5,6] which does not significantly increase cancer risk in other organs of women [7]. This raises a clinical and public health concern because nearly half of women of child-bearing age drink alcohol and 15% of drinkers at this age have four or more drinks at a time [8]. Approximately 4-10% of breast cancers in the USA are attributable to alcohol consumption [2,5,6], accounting for 9000-23,000 new invasive breast cancer cases each year. Therefore, better understanding of how alcohol consumption increases breast cancer risk is crucial for developing breast cancer prevention strategies. As previous meta-analyses and systemic reviews comprehensively summarized the association between adult alcohol consumption and breast cancer risk [3,5,9,10], here we reviewed the recent epidemiologic evidence, with special emphasis on timing and patterns of C 12 14 alcohol 7 eo on sumption and the effect of alcohol on intermediate markers. In addition, we discussed up-to-date mechanisms that have been proposed to explain the association and provide guidance for clinicians on preventive messages.
Ethoxylation is a chemical reaction in which ethylene oxide adds to a substrate. It is the most widely practiced alkoxylation, which involves the addition of epoxides to substrates.
In the usual application, alcohols and phenols are converted into R(OC2H4)nOH where n ranges from 1 to 10. Such compounds are called alcohol ethoxylates. Alcohol ethoxlates are often converted to related species called ethoxysulfates. Alcohol ethoxylates and ethoxysulfates are surfactants, used widely in cosmetic and other commercial products.[1] The process is of great industrial significance with more than 2,000,000 metric tons of various ethoxylates produced worldwide in 1994.
Production of C 12 14 alcohol 7 eo
The process was developed at the Ludwigshafen laboratories of I.G. Farben by Conrad Schöller and Max Wittwer during the 1930s.[3][4]
Alcohol ethoxylates
Industrial ethoxylation is primarily performed upon fatty alcohols in order to generate fatty alcohol ethoxylates (FAE’s), which are a common form of nonionic surfactant (e.g. octaethylene glycol monododecyl ether. Such alcohols may be obtained by the hydrogenation of fatty acids from seed oils,[5] or via hydroformylation in the Shell higher olefin process.[6] The reaction proceeds by blowing ethylene oxide through the alcohol at 180 °C and under 1-2 bar of pressure, with potassium hydroxide (KOH) serving as a catalyst.[7] The process is highly exothermic (?H -92000 J/mol of ethylene oxide reacted) and requires careful control to avoid a potentially disastrous thermal runaway.[7]
ROH + n C2H4O › R(OC2H4)nOH
The starting materials are usually primary alcohols as they react ~10-30x faster than do secondary alcohols.[8] Typically 5-10 units of ethylene oxide are added to each alcohol,[6] however ethoxylated alcohols can be more prone to ethoxylation than the starting alcohol, making the reaction difficult to control and leading to the formation of a product with varying repeat unit length (the value of n in the equation above). Better control can be afforded by the use of more sophisticated catalysts,[9] which can be used to generate narrow-range ethoxylates. Ethoxylated alcohols are considered to be a high production volume (HPV) chemical by the US EPA.[10]
Ethoxylation/propoxylation
Ethoxylation is sometimes combined with propoxylation, the analogous reaction using propylene oxide as the monomer. Both reactions are normally performed in the same reactor and may be run simultaneously to give a random polymer, or in alternation to obtain block copolymers such as poloxamers.[7] Propylene oxide is more hydrophobic than ethylene oxide and its inclusion at low levels can significantly affect the properties of the surfactant. In particular ethoxylated fatty alcohols which have been ‘capped’ with ~1 propylene oxide unit are extensively marketed as low-foaming surfactants.
Ethoxysulfates
Ethoxylated fatty alcohols are often converted to the corresponding organosulfates, which can be easily deprotonated to give anionic surfactants such as sodium laureth sulfate. Being salts, ethoxysulfates exhibit good water solubility (high HLB value). The conversion is achieved by treating ethoxylated alcohols with sulfur trioxide.[11] Laboratory scale synthesis may be performed using chlorosulfuric acid:
R(OC2H4)nOH + SO3 › R(OC2H4)nOSO3H
R(OC2H4)nOH + HSO3Cl › R(OC2H4)nOSO3H + HCl
The resulting sulfate esters are neutralized to give the salt:
R(OC2H4)nOSO3H + NaOH › R(OC2H4)nOSO3Na + H2O
Small volumes are neutralized with alkanolamines such as triethanolamine (TEA).[12][page needed] In 2006, 382,500 metric tons of alcohol ethoxysulfates (AES) were consumed in North America.[13](subscription required)[page needed][better source needed]
Other materials
Although alcohols are by far the major substrate for ethoxylation, many nucleophiles are reactive toward ethylene oxide. Primary amines will react to give di-chain materials such as polyethoxylated tallow amine. The reaction of ammonia produces important bulk chemicals such as ethanolamine, diethanolamine, and triethanolamine.
Applications of ethoxylated products
Alcohol ethoxylates (AE) and alcohol ethoxysulfates (AES) are surfactants found in products such as laundry detergents, surface cleaners, cosmetics, agricultural products, textiles, and paint.[14][non-primary source needed]
Alcohol ethoxylates
As alcohol ethoxylate based surfactants are non-ionic they typically require longer ethoxylate chains than their sulfonated analogues in order to be water-soluble.[15] Examples synthesized on an industrial scale include octyl phenol ethoxylate, polysorbate 80 and poloxamers. Ethoxylation is commonly practiced, albeit on a much smaller scale, in the biotechnology and pharmaceutical industries to increase water solubility and, in the case of pharmaceuticals, circulatory half-life of non-polar organic compounds. In this application, ethoxylation is known as “PEGylation” (polyethylene oxide is synonymous with polyethylene glycol, abbreviated as PEG). Carbon chain length is 8-18 while the ethoxylated chain is usually 3 to 12 ethylene oxides long in home products.[16][page needed] They feature both lipophilic tails, indicated by the alkyl group abbreviation, R, and relatively polar headgroups, represented by the formula (OC2H4)nOH.
Alcohol ethoxysulfates
C 12 14 alcohol 7 eo found in consumer products generally are linear alcohols, which could be mixtures of entirely linear alkyl chains or of both linear and mono-branched alkyl chains.[17][page needed] A high-volume example of these is sodium laureth sulfate a foaming agent in shampoos and toothpastes, as well as industrial detergents.
Alcohol ethoxylates (AEs)
Human health
Alcohol ethoxylates are not observed to be mutagenic, carcinogenic, or skin sensitizers, nor cause reproductive or developmental effects.[18] One byproduct of ethoxylation is 1,4-dioxane, a possible human carcinogen.[19] Undiluted C 12 14 alcohol 7 eo can cause dermal or eye irritation. In aqueous solution, the level of irritation is dependent on the concentration. C 12 14 alcohol 7 eo are considered to have low to moderate toxicity for acute oral exposure, low acute dermal toxicity, and have mild irritation potential for skin and eyes at concentrations found in consumer products.[16]
Aquatic and environmental aspects
C 12 14 alcohol 7 eo are usually released down the drain, where they may be adsorbed into solids and biodegrade through anaerobic processes, with ~28-58% degraded in the sewer.[20][non-primary source needed] The remaining C 12 14 alcohol 7 eo are treated at waste water treatment plants and biodegraded via aerobic processes with less than 0.8% of C 12 14 alcohol 7 eo released in effluent.[20] If released into surface waters, sediment or soil, C 12 14 alcohol 7 eo will degrade through aerobic and anaerobic processes or be taken up by plants and animals.
Toxicity to certain invertebrates has a range of EC50 values for linear AE from 0.1 mg/l to greater than 100 mg/l. For branched alcohol exthoxylates, toxicity ranges from 0.5 mg/l to 50 mg/l.[16] The EC50 toxicity for algae from linear and branched AEs was 0.05 mg/l to 50 mg/l. Acute toxicity to fish ranges from LC50 values for linear AE of 0.4 mg/l to 100 mg/l, and branched is 0.25 mg/l to 40 mg/l. For invertebrates, algae and fish the essentially linear and branched C 12 14 alcohol 7 eo are considered to not have greater toxicity than Linear AE.[16]
Alcohol ethoxysulfates (AESs)
Biodegradation
The degradation of C 12 14 alcohol 7 eo proceeds by ?- or ß-oxidation of the alkyl chain, enzymatic hydrolysis of the sulfate ester, and by cleavage of an ether bond in the AES producing alcohol or alcohol ethoxylate and an ethylene glycol sulfate. Studies of aerobic processes also found C 12 14 alcohol 7 eo to be readily biodegradable.[12] The half-life of both AE and C 12 14 alcohol 7 eo in surface water is estimated to be less than 12 hours.[21][non-primary source needed] The removal of C 12 14 alcohol 7 eo due to degradation via anaerobic processes is estimated to be between 75 and 87%.
Aquatic
Flow-through laboratory tests in a terminal pool of C 12 14 alcohol 7 eo with mollusks found the NOEC of a snail, Goniobasis and the Asian clam, Corbicula to be greater than 730 ug/L. Corbicula growth was measured to be affected at a concentration of 75 ug/L.[22][non-primary source needed] The mayfly, genus Tricorythodes has a normalized density NOEC value of 190 ug/L.[23][non-primary source needed]
Human Safety
C 12 14 alcohol 7 eo has not been found to be genotoxic, mutagenic, or carcinogenic.
LAURYL ALCOHOL ETHOXYLATES
C12-14 ALCOHOL 1 EO
C12-14 ALCOHOL 2 EO
C12-14 ALCOHOL 3 EO
C12-14 ALCOHOL 4 EO
C12-14 ALCOHOL 5 EO
C12-14 ALCOHOL 6 EO
C12-14 ALCOHOL 7 EO
C12-16 ALCOHOL 7 EO
C12-14 ALCOHOL 8 EO
C12-14 ALCOHOL 9 EO
C12-14 ALCOHOL 10 EO
C12-14 ALCOHOL 11 EO
C12-14 ALCOHOL 12 EO
C12-14 ALCOHOL 15 EO
C 12 14 alkol 7 eo
Alkoller, C12-14, etoksillenmi
1 – 2.5 mol etoksillenmi
Yasal ilem adlar 1 IUPAC adlar 30 Ticari isimler 377 Dier tanmlayclar 25
Infocard’ Yazdr Ksa Profili Aç
Madde kimlii
Yardm
EC / Liste no .: 500-213-3
CAS no .: 68439-50-9
Mol. formül: (C2H4O) 1-3 (CH2) 10-12C2H6O
formül
Snflandrma ve etiketleme
Yardm
Uyar! irketlerin REACH kaytlarnda ECHA’ya salad snflandrmaya göre C 12 14 alkol 7 eo sudaki yaam için çok toksiktir ve uzun süreli etkilerle sudaki yaam için zararldr.
C 12 14 alkol 7 eo hakknda
Yardmc bilgi
C 12 14 alkol 7 eo ylda 100 000-1000 000 ton arasnda Avrupa Ekonomik Alan’nda üretilmekte ve / veya ithal edilmektedir.
C 12 14 alkol 7 eo tüketiciler, profesyonel çalanlar tarafndan (yaygn kullanmlar), formülasyonda veya yeniden ambalajlamada, endüstriyel alanlarda ve imalatta kullanlr.
Tüketici Kullanmlar
C 12 14 alkol 7 eo aadaki ürünlerde kullanlmaktadr: ykama ve temizlik ürünleri, bitki koruma ürünleri, gübreler, yalayclar ve gresler, hava bakm ürünleri ve yaktlar.
C 12 14 alkol 7 eo ortamna dier salmlarn meydana gelmesi muhtemeldir: iç mekan kullanm (örn. Makine ykama svlar / deterjanlar, otomotiv bakm ürünleri, boyalar ve kaplama veya yaptrclar, kokular ve oda spreyleri), d mekan kullanm, iç mekan kullanm minimal serbest brakmal kapal sistemler (örn. buzdolaplarndaki soutma svlar, ya bazl elektrikli stclar) ve minimum serbest brakmal kapal sistemlerde (örn. otomotiv süspansiyonundaki hidrolik svlar, motor ya ve fren svlar).
Makale hizmet ömrü
ECHA’nn C 12 14 alkol 7 eo’nun çevreye salnmasnn muhtemel olduu yollarla ilgili kamuya açk kaytl verileri yoktur. ECHA’nn, maddenin ilenip ilenmediini veya hangi ürünlere ilenmi olabileceini gösteren kamuya açk verileri yoktur.
Profesyonel çalanlar tarafndan yaygn kullanm
C 12 14 alkol 7 eo aadaki ürünlerde kullanlmaktadr: ykama ve temizlik ürünleri ile cilalar ve mumlar.
C 12 14 alkol 7 eo aadaki alanlarda kullanlr: karmlarn formülasyonu ve / veya yeniden paketleme, belediye arz (örn. Elektrik, buhar, gaz, su) ve kanalizasyon artma ve salk hizmetleri.
C 12 14 alkol 7 eo, kimyasallarn üretiminde kullanlr.
C 12 14 alkol 7 eo’nun çevreye baka salnm aadakilerden kaynaklanabilir: iç mekan kullanm (örn. Makine ykama svlar / deterjanlar, otomotiv bakm ürünleri, boyalar ve kaplama veya yaptrclar, kokular ve oda spreyleri) ve d mekan kullanm.
Formülasyon veya yeniden paketleme
C 12 14 alkol 7 eo aadaki ürünlerde kullanlmaktadr: ykama ve temizlik ürünleri, yalayclar ve gresler, metal ileme svlar, gübreler ve kozmetikler ve kiisel bakm ürünleri.
C 12 14 alkol 7 eo’nun ortamna salnm endüstriyel kullanmdan kaynaklanabilir: karmlarn formülasyonu, endüstriyel tesislerdeki ileme yardmclarnda ve malzemelerde formülasyon.
Sanayi alanlarnda kullanm
C 12 14 alkol 7 eo aadaki ürünlerde kullanlmaktadr: ykama ve temizlik ürünleri, metal yüzey ileme ürünleri, yalayclar ve gresler ve metal ileme svlar.
C 12 14 alkol 7 eo aadaki alanlarda kullanlr: karmlarn formülasyonu ve / veya yeniden paketleme ve belediye arz (örn. Elektrik, buhar, gaz, su) ve kanalizasyon artm.
C 12 14 alkol 7 eo, kimyasallarn, makinelerin ve tatlarn ve fabrikasyon metal ürünlerin imalat için kullanlr.
C 12 14 alkol 7 eo ortamna salnm endüstriyel kullanmdan kaynaklanabilir: endüstriyel tesislerde ileme yardmclarnda, kapal sistemlerde en az serbest brakma ve karm formülasyonu olan maddelerin.
C 12 14 alkol 7 eo imalat
C 12 14 alkol 7 eo çevreye salnm endüstriyel kullanmdan kaynaklanabilir: maddenin üretimi.
C 12 14 alkol 7 eo nasl güvenle kullanlr
Yardm
ECHA’nn C 12 14 alkol 7 eo kullanm için alnacak önlemlerle ilgili kayt dosyalarndan veri yoktur.
C 12 14 alkol 7 eo üreticileri ve ithalatçlar tarafndan salanan maddenin güvenli kullanm hakknda rehberlik.
C 12 14 7 EO noniyonik yüzey aktif madde. Latronol L 7, su emülsiyonlatrcda renksiz ve kokusuz bir sv ve verimli (O / W) bir yadr. Ayn zamanda biyolojik olarak parçalanabilir. Evde bakm, tekstil, resim / kaplama ve tarmsal uygulamalarda kullanlabilir.
C12-14 Alkol Etoksilatlar (7EO) (C 12 14 alkol 7 eo)
oleokimyasal noniyonik yüzey aktif madde
Madde Tanmlama
IUPAC Ad Alkoller, C12-14 (çift
numaralandrlm), etoksillenmi CAS Numaras 68439-50-9
Dier simler Lauril Alkol Etoksilat
C 12 14 alkol 7 eo Moleküler formül
UVCB maddesi (maddeler
Bilinmeyen veya Deiken
kompozisyon, Kompleks
reaksiyon ürünleri veya
Biyolojik malzemeler), hayr
tek odakl moleküler formül
mevcut
C 12 14 alkol 7 eo Yapsal formül:
C 12 14 alkol 7 eo n Fiziksel / Kimyasal C 12 14 alkol 7 eo Özellikler [1,2]
C 12 14 alkol 7 eoMoleküler Arlk 494.70-522.75 g / mol
C 12 14 alkol 7 eo Fiziksel durum Sv
C 12 14 alkol 7 eo Görünüm Renksiz, homojen ve opak
C 12 14 alkol 7 eo Koku Hafif karakteristik
C 12 14 alkol 7 eo Younluk 20 ° C’de 0.9 g / cm³ (C12-14 AE2’den proxy)
C 12 14 alkol 7 eo Erime Noktalar 25-35 ° C
C 12 14 alkol 7 eo Kaynama noktas 101.4 kPa’da 266.95 ° C (C12-14 AE2’den proxy)
C 12 14 alkol 7 eo Parlama Noktas 101.4 kPa’da 149 ° C (Alkol C1’den proxy)
2-14, etoksillenmi (1-2.5 EO))
C 12 14 alkol 7 eo Buhar Basnc 25 ° C’de 0,014 – 0,11 Pa
C 12 14 alkol 7 eo Suda Çözünürlük 25 ° C’de 15 mg / l
C 12 14 alkol 7 eo Tutuabilirlik Kullanlabilir veriler yok
C 12 14 alkol 7 eo Patlayc Özellikler Kullanlabilir veriler yok
C 12 14 alkol 7 eo Yüzey Gerilimi 20 ° C’de 27 mN / m (C12-14 AE2’den proxy)
Oktanol / su
Ayrlm katsays
C 12 14 alkol 7 eo (Kow)
log KOW = 4.63 – 5.71
Ürün ve Süreç
Açklama
C 12 14 alkol 7 eo, alkol etoksilatlar grubuna ait, 7 mol ile iyonik olmayan bir yüzey aktif cismidir.
etilen oksit. Yedi etilen oksit birimine sahip alkol etoksilatlar, reaksiyonla üretilir.
etilen oksit ile C 12 14 alkol 7 eo . C 12 14 alkol 7 eo ilavesi
alkoller, homolog polietilen glikol eter gruplarnn bir dalmna yol açar.
Etoksilasyon reaksiyonu, örn., Alkalin katalizörler ile katalize edilebilir. potasyum hidroksit veya
asidik katalizörler örn. bor triflorür veya çinko klorür. Deterjan aral alkol etoksilatlar için,
alkalin katalizi normal olarak kullanlr.
Ara etilen oksit, endüstriyel olarak etilenin dorudan oksidasyonu ile üretilir.
gümü katalizörün varl (Etilen oksit üretiminin dier detaylar Eco
Tarih: 02/06/2017
2
Öncü etilen oksit (# 8)) profil sayfas.
Uygulama
Kiisel Bakm: ampuan ve Banyo Jellerinde Köpük Ajan.
Deterjanlar: Deterjanlar, Çamar Ön Kireçleri ve Sert Yüzey Temizleyicilerdeki Islatc
Yüzey Aktif Maddeler ve Esterler: SLES (Sodyum Lauril Eter) Yapmak çin Sülfonatlanm Yüzey Aktif Madde Ara Maddesi
Sülfat). Hem ev hem de endüstriyel ürünlerde kullanlr.
Tekstil: Tekstil ve Deri lemede Islatc.
Yaam döngüsü Deerlendirmesi
Genel Tantm
Bu Çevresel Bilgi Sayfalar, ERASM Sürfaktan Yaam Döngüsü ve Eko Ayak zi (SLE) projesinin bir ürünüdür.
Bu projenin amac, 15 yüzey aktif madde ve 17 öncünün mevcut çevresel profilini oluturmak veya güncellemekti.
gerçek yüzey aktif madde üretim teknolojisi ve tutarl yüksek kaliteli arka plan verileri dikkate alnmaldr.
Eko-profiller yaam döngüsü deerlendirmesine (LCA) dayanmaktadr ve ISO standard [ISO
14040: 2006 ve ISO 14044: 2006]. Ayrca, proje ILCD (2010) el kitabn takip etmektedir. Bu Bilgi Föyü
C 12 14 alkol 7 eo için beikten kapya üretim. C 12 14 alkol 7 eo petrokimyasal bir yüzey aktif maddedir.
ERASM SLE projesi, sürfaktann tam “beikten mezara” yaam döngüsü balamnda salanan verilerin,
gerçek uygulama.
ERASM SLE projesi ve bu veri setlerinin kayna hakknda daha fazla bilgi [3] ‘te bulunabilir.
Tam LCI’ye www.erasm.org veya http://lcdn.thinkstep.com/Node/ adresinden eriilebilir.
ERASM SLE Projesinin Amaç ve Kapsam [3]
Ana hedef, C 12 14 alkol 7 eo ve ana üretimi için mevcut LCI envanterlerini [4,6] güncellemekti.
ön / ara maddeleri.
Geçici Kapsam
Toplanan veriler, 2011 ylnda 12 12 C7 alkol 7 eo üretiminin 12 aylk ortalamalarn temsil etmektedir.
verilerin mevsimsel etkisini telafi eder. Veri kümesinin, önemli olana kadar geçerli olduu kabul edilir
üretim zincirinde teknolojik deiiklikler meydana gelir.
Corafi Kapsam Güncel veriler, Avrupa’da C 12 14 alkol 7 eo üretimini temsil eden üç tedarikçiye dayanmaktadr.
C 12 14 alkol 7 eo’nun corafi temsili “iyi” olarak kabul edildi
Teknolojik
Kapsama
C 12 14 alkol 7 eo’nun teknolojik temsili “iyi” olarak kabul edildi.
ekil 1, C1214 alkol 7 eo’nun üretim prosesine ematik bir genel bak sunmaktadr.
Temsilcilii
Pazar hacmi>% 60 (ERASM SLE projesinde kullanlan birincil verilerin kapsad temsil edilen pazar hacmi (toplu olarak))
Beyan Edilen Birim
ERASM SLE projesinde beyan edilen ünite (fonksiyonel ünite) ve referans ak bin kilogramdr
(1000 kg) sürfaktan aktif muhteviyat. Bu [4] ‘te de kullanlan referans birimiydi.
Fonksiyonel Birim: 1 metrik ton C 12 14 alkol 7 eo% 100 aktif madde.
Beik – Kap Sistemi
Snrlar
Dahil Hariç Tutuldu
Ya alkolü C12-14 (oleo) üretimi (bu
üretim Eko-Profil’de daha fazla açklanmaktadr
öncü C12-14 ya alkolünün bilgi formu
(# 3))
Büyük sermaye ekipman inaat
(Altyap)
Etilen oksit üretimi (bu üretim
Eko-Profil bilgi formunda ayrca açklanmtr
öncü etilen oksit (# 8))
Destek ve bakm destei
ekipman
Enerji üretimi nsan içilii ve çalan tamacl
Yardmc Ambalaj
Ana malzemeler için nakliye ilemleri
Tarih: 02/06/2017
3
Su kullanm ve atk suyun artlmas
Atklarn artlmas
Varsaymlar ve
Snrlamalar
Ulam sadece ana malzemeler için düünülmütür (herkesin kütlesinin yaklak% 95’ini kapsar)
dier tamaclk dikkate alnmamtr.
Kesme Kriterleri [5]
Önemli bir kesim kullanlmad.
LCI çalmas, toplamda (birim ilem seviyesine atfta bulunur)
toplam kütle girdilerinin en az% 98’i nit ilemine tabi tutuldu ve
birim prosese toplam enerji girdilerinin en az% 98’i toplam.
Çalma, ekstraksiyonu, üretimi,
kullanm veya imha, yüksek derecede toksik, çevre için tehlikeli veya tehlikeli atk olarak snflandrlmtr.
Hariç tutulan malzeme aklarnn toplam kütle, enerji veya çevresel maddelerin% 5’ini geçmedi
alaka.
Hesaplama Kurallar
Tahsis
C 12 14 alkol 7 eo üretimi için, ön plan sistemine tahsis yaplmamtr.
Bununla birlikte, baz arka plan verileri için ayrma uyguland (
yenilenebilir öncüler PKO ve CNO).
Toplu
veri
Dikey ortalama dikkate alnmtr (nihai ürün ayn olduu sürece, farkl
ortak ürün ara ürünlerine sahip ilemler ortalama olarak toplanabilir)
Yaam Döngüsü Envanteri ve Etki Deerlendirmesi [3]
LCI verilerine dayanarak, Birincil Enerji Talebi (PED) göstergeleri için çevresel etki deerlendirmesi yapld ve
Küresel Isnma Potansiyeli (GWP). Dier etkiler tam LCI veri kümesinden hesaplanabilir.
Birincil Enerji Talebi (PED): Envanter verilerinin analizi, ana katknn ana ham
malzemeler C12-14 ya alkolü ve etilen oksit (birlikte yaklak% 90 katk). Elektrik ve termal enerji
üretimi her biri PED’in% 3-5’ine neden olur. Dorudan proses emisyonlar, dier kimyasallar, kamu hizmetleri, proses atk artm ve
ulamn ilgili bir etkisi yoktur (her biri% 0.5 daha küçük). Doal yal alkollere dayanan alkol etoksilatlar
kaynaklarn petrokimyasal hammaddeye göre birincil enerji talebi daha düüktür.
Küresel Isnma Potansiyeli (GWP): Envanter verilerinin analizi, ana katknn ana
hammaddeler C12-14 ya alkolü ve etilen oksit (birlikte yaklak% 90 katk). Elektrik ve termal enerji
üretimi her biri GWP’nin% 3-5’ine neden olur. Dorudan proses emisyonlar, dier kimyasallar, kamu hizmetleri, proses atk artm ve
ulamn ilgili bir etkisi yoktur (her biri% 0.5 daha küçük).
C 12 14 alkol 7 eo karbon alm için yüksek deer, ana öncü C 12 14 alkol 7 eo’ya baldr.
hurma çekirdei ya ve hindistancevizi ya.
C 12 14 alkol 7 eo’nun alkolden daha düük bir GWP’si olduundan, C 12 14 alkol 7 eo’da daha yüksek bir C 12 14 alkol 7 eo pay, C 12 14 alkol 7 eo 3’e göre daha düük bir GWP ile sonuçlanr.
Doal kaynaklardan elde edilen ya alkollerine dayanan alkol etoksilatlar, küresel kaynaklardan daha düük bir küresel snma potansiyeline sahiptir.
petrokimyasal hammaddeye dayal
C 12 14 alkol 7 eo, alkol etoksilatlar grubuna ait, 7 mol etilen oksit ile iyonik olmayan bir yüzey aktif maddedir. Yedi etilen oksit birimine sahip alkol etoksilatlar, C12-C14 ya alkollerinin (oleo) etilen oksit ile reaksiyonu yoluyla üretilir. C12-14 ya alkollerine etilen oksit ilavesi, homolog polietilen glikol eter gruplarnn dalmna yol açar.
Etoksilasyon reaksiyonu, örn., Alkalin katalizörler ile katalize edilebilir. potasyum hidroksit veya örn., asidik katalizörler ile bor triflorür veya çinko klorür. Deterjan aral alkol etoksilatlar için, normal olarak alkalin kataliz kullanlr.
Ara etilen oksit endüstriyel olarak gümü katalizör varlnda etilenin dorudan oksidasyonu ile üretilir (Etilen oksit üretiminin dier detaylar öncü etilen oksidin Eko Profil bilgi formunda açklanmaktadr.
C 12 14 alkol 7 eo uygulamalar
Kiisel Bakm: ampuan ve Banyo Jellerinde Köpük Ajan.
Deterjanlar: Deterjanlar, Çamar Ön Kireçleri ve Sert Yüzey Temizleyicilerdeki Islatc
Sürfaktanlar ve Esterler: Sürfaktan Ara Maddesi, SLES (Sodyum Lauril Eter Sülfat) Yapm çin Sülfonatlandrlmtr. Hem ev hem de endüstriyel ürünlerde kullanlr.
Tekstil: Tekstil ve Deri lemede Islatc.
Bu Çevresel Bilgi Sayfalar, ERASM Sürfaktan Yaam Döngüsü ve Eko Ayak zi (SLE) projesinin bir ürünüdür.
Bu projenin amac, 15 yüzey aktif madde ve 17 öncünün mevcut çevresel profilini oluturmak veya güncellemekti.
gerçek yüzey aktif madde üretim teknolojisi ve tutarl yüksek kaliteli arka plan verileri dikkate alnmaldr.
Eko-profiller yaam döngüsü deerlendirmesine (LCA) dayanmaktadr ve ISO standard [ISO
14040: 2006 ve ISO 14044: 2006]. Ayrca, proje ILCD (2010) el kitabn takip etmektedir. Bu Bilgi Föyü
C 12 14 alkol 7 eo için beikten kapya üretim. C1214 alkol 7 eo petrokimyasal bir yüzey aktif maddedir.
ERASM SLE projesi, yüzey aktif maddenin tam beie-mezara ‘yaam döngüsü balamnda salanan verilerin
gerçek uygulama.
ERASM SLE projesi ve bu veri kümelerinin kayna hakknda daha fazla bilgi için:
LCI verilerine dayanarak, Birincil Enerji Talebi (PED) göstergeleri için çevresel etki deerlendirmesi yapld ve
Küresel Isnma Potential (GWP). Dier etkiler tam LCI veri kümesinden hesaplanabilir.
Birincil Enerji Talebi (PED): Envanter verilerinin analizi, ana katknn ana ham
malzemeler C 12 14 alkol 7 eo ve etilen oksit (birlikte yaklak% 90 katk). Elektrik ve termal enerji
üretimi her biri PED’in% 3-5’ine neden olur. Dorudan proses emisyonlar, dier kimyasallar, kamu hizmetleri, proses atk artm ve
ulamn ilgili bir etkisi yoktur (her biri% 0.5 daha küçük). Doal yal alkollere dayanan alkol etoksilatlar
kaynaklarn petrokimyasal hammaddeye göre birincil enerji talebi daha düüktür.
Küresel Isnma Potansiyeli (GWP): Envanter verilerinin analizi, ana katknn ana
hammaddeler C 12 14 alkol 7 eo ve etilen oksit (birlikte yaklak% 90 katk). Elektrik ve termal enerji
üretimi her biri GWP’nin% 3-5’ine neden olur. Dorudan proses emisyonlar, dier kimyasallar, kamu hizmetleri, proses atk artm ve
ulamn ilgili bir etkisi yoktur (her biri% 0.5 daha küçük).
C 12 14 alkol 7 eo etoksilatn karbon alm için yüksek deer, ana öncü C 12 14 alkol 7 eo’ya baldr.
hurma çekirdei ya ve hindistancevizi ya.
EO, alkolden daha düük bir GWP’ye sahip olduundan, C1214 alkol 7 eo’da daha yüksek bir EO pay, C12-14 AE3’e göre daha düük bir GWP ile sonuçlanr.
Doal kaynaklardan elde edilen ya alkollerine dayanan alkol etoksilatlar, küresel kaynaklardan daha düük bir küresel snma potansiyeline sahiptir.
petrokimyasal hammaddeye dayal.
C 12 14 alkol 7 eo Uygulama
Çamar tozu
Çamarhane tabletleri
Çamar svlar
Ön tedavi ajanlar
Çok amaçl temizleyiciler
Banyo temizleyicileri
Shhi temizleyiciler
Bulak ykama svlar
Temizlik ürünleri
Araç temizleyicileri
ampuanlar
Du jeli
Kozmetik temizleme emülsiyonlar
Tekstil üretimi ve deri ileme yardmclar
Teknik ilemler için emülsiyonlar
7 mol EO içeren ya alkolü etoksilat C12-14 bazl sodyum lauril eter sülfat
20 ° C scaklkta berrak sarms sv
20 ° C’de younluk, g / cm3, c. 1.05
katlar, a.% 27 ± 1
sodyum sülfat, arlkça%, maks. 0.8
pH,% 10 sulu çözelti 7.0 – 8.5
C 12 14 alkol Yetikin kadnlarn 7 eo tüketimi sürekli olarak meme kanseri riski ile ilikilidir. Alkol ve meme kanseri ile ilgili çeitli sorularn ele alnmas gerekmektedir. lk gebelie menar, meme dokusunun kanserojenlere özellikle duyarl olduu bir zaman penceresini temsil eder. ABD’de gençlik alkol tüketimi, büyük ölçüde tknrcasna içme ve ar içme eklinde yaygndr. Alkol almnn meme tümör oluumu sürecinde erken davranp davranmad belirsizdir. Bu derleme, alkol tüketiminin zamanlamas ve örüntülerinin etkileri ile C 12 14 alkol 7 eo’nun ara risk belirteçleri üzerindeki etkisine odaklanmay amaçlamaktadr. Alkol-meme kanseri birlikteliinin altnda yatan olas mekanizmalar da gözden geçiriyoruz.
C 12 14 alkol 7 eol, Uluslararas Kanser Aratrmalar Ajans tarafndan meme kanseri riskiyle [1] nedensel olarak ilikili olduu düünülmektedir [1], günlük olarak tüketilen her 10 g (~ 1 içecek) alkol için% 7-10 risk art yetikin kadnlar [2-4]. Bu iliki hem premenopozal hem de postmenopozal kadnlarda görülür. Dier organlarla karlatrldnda, meme alkolün kanserojen etkilerine daha duyarl görünmektedir. Meme kanseri riski, kadnlarn dier organlarnda kanser riskini önemli ölçüde artrmayan hafif alkol tüketimi (? 1 içecek / gün veya? 12.5 g / gün) [2,5,6] için% 4-15 orannda önemli ölçüde artmtr [ 7]. Bu klinik ve halk sal için bir endie yaratr çünkü çocuk dourma yandaki kadnlarn yaklak yarsnda alkol ve bu yataki içenlerin% 15’inde bir seferde dört veya daha fazla içecek vardr [8]. ABD’deki meme kanserlerinin yaklak% 4-10’u, her yl 9000-23.000 yeni invaziv meme kanseri vakas oluturan alkol tüketimine balanabilir [2,5,6]. Bu nedenle, alkol tüketiminin meme kanseri riskini nasl arttrdn daha iyi anlamak, meme kanseri önleme stratejileri gelitirmek için çok önemlidir. Önceki meta-analizler ve sistemik incelemeler yetikin alkol tüketimi ve meme kanseri riski arasndaki ilikiyi kapsaml bir ekilde özetlediinden [3,5,9,10], burada C 12 14 alkolün zamanlamas ve örüntülerine özel vurgu ile son epidemiyolojik kantlar gözden geçirdik. 7 alkol tüketimi ve ara iaretleyiciler üzerindeki etkisi. Ayrca, dernei açklamak ve klinisyenlere önleyici mesajlar konusunda rehberlik etmek için önerilen güncel mekanizmalar tarttk.
Etoksilasyon, etilen oksidin bir substrata ekledii kimyasal bir reaksiyondur. Substratlara epoksitlerin eklenmesini içeren en yaygn uygulanan alkoksilasyondur.
Olaan uygulamada, alkoller ve fenoller n’nin 1 ila 10 arasnda deitii R (OC2H4) nOH’ye dönütürülür. Bu tür bileiklere alkol etoksilatlar denir. Alkol etokslatlar genellikle etoksisülfatlar olarak adlandrlan ilgili türlere dönütürülür. Alkol etoksilatlar ve etoksisülfatlar, kozmetikte ve dier ürünlerde yaygn olarak kullanlan sürfaktanlardr.
C 12 14 alcool 7 eo
Alcools en C12-14, éthoxylés
1 – 2,5 moles éthoxylées
Noms des processus réglementaires 1 Noms IUPAC 30 Noms commerciaux 377 Autres identifiants 25
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Identité de la substance
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N ° CE / Liste: 500-213-3
No CAS: 68439-50-9
Mol. formule: (C2H4O) 1-3 (CH2) 10-12C2H6O
formule
Classification et étiquetage des dangers
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Attention! Selon la classification fournie par les entreprises à l’ECHA dans les enregistrements REACH, l’alcool C 12 14 7 eo est très toxique pour la vie aquatique et est nocif pour la vie aquatique avec des effets durables.
À propos de C 12 14 alcool 7 eo
Information utile
L’alcool C 12 14 7 eo est fabriqué et / ou importé dans l’Espace économique européen en 100 000 – 1 000 000 tonnes par an.
L’alcool C 12 14 7 eo est utilisé par les consommateurs, par les professionnels (utilisations répandues), dans la formulation ou le reconditionnement, sur les sites industriels et dans la fabrication.
Usages des consommateurs
L’alcool C 12 14 7 eo est utilisé dans les produits suivants: produits de lavage et de nettoyage, produits phytosanitaires, engrais, lubrifiants et graisses, produits de soin de l’air et carburants.
Une autre libération dans l’environnement d’alcool C 12 14 7 eo est susceptible de se produire à partir de: utilisation à l’intérieur (par exemple, liquides de lavage / détergents pour la machine, produits d’entretien automobile, peintures et revêtements ou adhésifs, parfums et assainisseurs d’air), utilisation à l’extérieur, utilisation à l’intérieur dans systèmes fermés à dégagement minimal (par exemple, liquides de refroidissement dans les réfrigérateurs, radiateurs électriques à base d’huile) et utilisation en extérieur dans des systèmes fermés à dégagement minimal (par exemple, liquides hydrauliques dans les suspensions automobiles, lubrifiants dans l’huile à moteur et liquides de casse).
Durée de vie de l’article
L’ECHA ne dispose d’aucune donnée publique enregistrée sur les voies par lesquelles l’alcool C 12 14 7 eo est le plus susceptible d’être rejeté dans l’environnement. L’ECHA ne dispose d’aucune donnée publique enregistrée indiquant si ou dans quels articles la substance a pu être transformée.
Utilisations généralisées par les travailleurs professionnels
L’alcool C 12 14 7 eo est utilisé dans les produits suivants: produits de lavage et de nettoyage et cirages et cires.
L’alcool C 12 14 7 eo est utilisé dans les domaines suivants: formulation de mélanges et / ou reconditionnement, approvisionnement municipal (par exemple électricité, vapeur, gaz, eau) et traitement des eaux usées et services de santé.
L’alcool C 12 14 7 eo est utilisé pour la fabrication de: produits chimiques.
Une autre libération dans l’environnement d’alcool C 12 14 7 eo est susceptible de se produire à partir de: l’utilisation à l’intérieur (par exemple, liquides / détergents de lavage en machine, produits d’entretien automobile, peintures et revêtements ou adhésifs, parfums et assainisseurs d’air) et l’utilisation à l’extérieur.
Formulation ou reconditionnement
L’alcool C 12 14 7 eo est utilisé dans les produits suivants: produits de lavage et de nettoyage, lubrifiants et graisses, fluides pour le travail des métaux, engrais et cosmétiques et produits de soins personnels.
La libération dans l’environnement d’alcool C 12 14 7 eo peut se produire à partir d’une utilisation industrielle: formulation de mélanges, dans des auxiliaires technologiques sur des sites industriels et formulation dans des matériaux.
Utilisations sur sites industriels
L’alcool C 12 14 7 eo est utilisé dans les produits suivants: produits de lavage et de nettoyage, produits de traitement de surface des métaux, lubrifiants et graisses et fluides de travail des métaux.
L’alcool C 12 14 7 eo est utilisé dans les domaines suivants: formulation de mélanges et / ou reconditionnement et approvisionnement municipal (par exemple électricité, vapeur, gaz, eau) et traitement des eaux usées.
L’alcool C 12 14 7 eo est utilisé pour la fabrication de: produits chimiques, machines et véhicules et produits métalliques ouvrés.
La libération dans l’environnement d’alcool C 12 14 7 eo peut se produire à partir d’une utilisation industrielle: dans les auxiliaires technologiques des sites industriels, de substances dans des systèmes fermés avec une libération et une formulation minimales des mélanges.
Fabrication d’alcool C 12 14 7 eo
La libération dans l’environnement d’alcool C 12 14 7 eo peut se produire à partir d’une utilisation industrielle: fabrication de la substance.
Comment utiliser l’alcool C 12 14 7 eo en toute sécurité
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L’ECHA ne dispose pas de données provenant des dossiers d’enregistrement sur les mesures de précaution pour l’utilisation d’alcool C 12 14 7 eo.
Lignes directrices sur l’utilisation sûre de la substance fournies par les fabricants et les importateurs d’alcool en C 12 14 7 eo.
Surfactant non ionique C 12 14 7 EO. Le Latronol L 7 est un émulsifiant liquide et incolore liquide et inodore (O / W) dans l’eau. Il est également biodégradable. Peut être utilisé dans les soins à domicile, le textile, les peintures / revêtements et les applications agricoles.
Éthoxylates d’alcool C12-14 (7EO) (C12-14
AE7)
Tensioactif non ionique oléochimique
Identification de la substance
IUPAC Name Alcohols, C12-14 (pairs
numéroté), éthoxylé Numéro CAS 68439-50-9
Autres noms éthoxylate d’alcool laurique
Formule moléculaire
Substance UVCB (substances
Inconnu ou variable
composition, Complexe
produits de réaction ou
Matériel biologique), non
formule moléculaire univoque
disponible
Formule structurelle:
Propriétés physiques / chimiques [1,2]
Poids moléculaire 494,70 -522,75 g / mol
État physique Liquide
Aspect Incolore, homogène et opaque
Odeur Légère caractéristique
Densité 0,9 g / cm³ à 20 ° C (proxy de C12-14 AE2)
Points de fusion 25 – 35 ° C
Point d’ébullition 266,95 ° C à 101,4 kPa (proxy de C12-14 AE2)