CALCIUM LABSA (KALSYUM LABSA)

CAS No. : 27176-87-0

EC No. : 248-289-4

Synonyms:

Calcium linear alkyl benzene sulphonic acid; Calcium dodecylbenzenesulphonate; LAS; LABSA; LABS; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; Linear Alkylbenzene Sulphonic Acid; DDBSA; Dodecyl Benzene Sulphonic Acid; Dodecyl Benzene Sulfonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; CALCIUM LABSA; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); LNEER ALKL BENZEN SÜLFONK AST; lineer alkil benzen sülfonik asit; Dodecylbenzene Sulfonic Acid (Strait Chain); Calcium labsa; Calcium labs; LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Linear alkyl benzene Sulphonic Acid (LABSA); KALSYUM LABSA; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; N-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); LNEER ALKL BENZEN SÜLFONK AST; lineer alkil benzen sülfonik asit; LAS; LABSA; LABS; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; Linear Alkylbenzene Sulphonic Acid; DDBSA; Dodecyl Benzene Sulphonic Acid; Dodecyl Benzene Sulfonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Linear alkyl benzene Sulphonic Acid (LABSA); Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Calcium labsa; Calcium labs; Laurylbenzenesulfonate; N-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); KALSYUM LABSA; LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); CALCIUM LABSA; LAS; LABSA; LABS; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; Linear Alkylbenzene Sulphonic Acid; DDBSA; Dodecyl Benzene Sulphonic Acid; Dodecyl Benzene Sulfonic Acid; CALCIUM LABSA; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); LNEER ALKL BENZEN SÜLFONK AST; lineer alkil benzen sülfonik asit; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Linear alkyl benzene Sulphonic Acid (LABSA); Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; N-Dodecylbenzene Sulfonic Acid; Calcium labsa; Calcium labs; Alkylbenzene sulphonate, sodium salt; KALSYUM LABSA; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French);LNEER ALKL BENZEN SÜLFONK AST; lineer alkil benzen sülfonik asit; LAS; LABSA; LABS; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; Linear Alkylbenzene Sulphonic Acid; DDBSA; Dodecyl Benzene Sulphonic Acid; Dodecyl Benzene Sulfonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); LNEER ALKL BENZEN SÜLFONK AST; lineer alkil benzen sülfonik asit; CALCIUM LABSA; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Linear alkyl benzene Sulphonic Acid (LABSA); Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA; Laurylbenzenesulfonic Acid; KALSYUM LABSA; Laurylbenzenesulfonate; N-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzene Sulfonic Acid (Strait Chain); Calcium labsa; Calcium labs; LAS; LABSA; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); LNEER ALKL BENZEN SÜLFONK AST; lineer alkil benzen sülfonik asit

Calcium LABSA

CLASSIFICATION

Anionic Surfactant

DESCRIPTION OF Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)

Linear alkyl benzene sulphonic acid is the largest-volume synthetic surfactant because of its relatively low cost, good performance, the fact that it can be dried to a stable powder and the biodegradable environmental friendliness as it has straight chain. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is an anionic surfactants with molecules characterized by a hydrophobic and a hydrophilic group. Alpha-olefin sulfonates (AOS) alkyl sulfates (AS) are also examples of commercial anionic surfactants. They are nonvolatile compounds produced by sulfonation. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are complex mixtures of homologues of different alkyl chain lengths (C10 to C13 or C14) and phenyl positional isomers of 2 to 5-phenyl in proportions dictated by the starting materials and reaction conditions, each containing an aromatic ring sulfonated at the para position and attached to a linear alkyl chain at any position with the exception of terminal one (1-phenyl). The properties of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) differ in physical and chemical properties according to the alkyl chain length, resulting in formulations for various applications. The starting material Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) (linear alkylbenzene) is produced by the alkylation of benzene with n-paraffins in the presence of hydrogen fluoride (HF) or aluminium chloride (AlCl3) as a catalyst. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is produced by the sulfonation of LAB with oleum in batch reactors. Other sulfonation alternative reagents are sulfuric acid, diluted sulfur trioxide, chlorosulfonic acid and sulfamic acid on falling film reactors. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are then neutralized to the desired salt (sodium, ammonium, calcium, potassium, and triethanolamine salts). Surfactants are widely used in the industry needed to improve contact between polar and non-polar media such as between oil and water or between water and minerals. Linear alkyl benzene sulphonic acid is mainly used to produce household detergents including laundry powders, laundry liquids, dishwashing liquids and other household cleaners as well as in numerous industrial applications like as a coupling agent and as an emulsifier for agricultural herbicides and in emulsion polymerization.

PHYSICAL AND CHEMICAL PROPERTIES

Household detergents including laundry powders, laundry liquids, dishwashing liquids and other household cleaners. Industrial applications of wetting agent, emulsifier for agricultural herbicides and in polymerization.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is prepared commercially by sulfonating linear alkylbenzene (LAB). Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), the world’s largest-volume synthetic surfactant, which includes the various salts of sulfonated alkylbenzenes, is widely used in household detergents as well as in numerous industrial applications. The Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) market is driven by the markets for Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), primarily household detergents. Linear alkylbenzene sulfonate was developed as a biodegradable replacement for nonlinear (branched) alkylbenzene sulfonate (BAS) and has largely replaced BAS in household detergents throughout the world.

The pattern of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) consumption demonstrates the overwhelming preference by consumers for liquid laundry detergents in North America, whereas powders continue to be the dominant products in Western Europe, Japan, and China. Comparable and reliable data in other world regions are generally unavailable. In these less-developed world areas, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is essentially used only in laundry powders (particularly in India and Indonesia) and hand dishwashing liquids. The latter are often used as general-purpose cleaners.

The following pie chart shows world consumption of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA):

About 82-87% of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in household detergents, including laundry powders, laundry liquids, dishwashing liquids, and other household cleaners. Industrial, institutional, and commercial cleaners account for most of the other applications, but Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is also used as an emulsifier (e.g., for agricultural herbicides and in emulsion polymerization) and as a wetting agent. Very small volumes are also used in personal care applications. Demand in the North American household segment fell sharply in 2000-11, as a result of several developments, including reformulations away from Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) to alternative surfactants because of cost considerations, the greater use of enzymes, and adverse economic conditions that resulted in lower overall surfactant levels in detergents. However, consumption stabilized during 2011-17.

Although consumption of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) will likely stabilize or decline slightly in the highly developed regions, it will increase by 3.0-5.0% in some less-developed regions or countries, such as the Middle East, Africa, India, and China, as well as Southeast Asia. As a result of the rapid growth of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) demand in the Asia Pacific region, demand in the region accounted for over half of global demand in 2017.

The worldwide growth of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) will be negatively impacted by the efforts of detergent manufacturers to reduce the active content in their surfactant formulations, by the shift to liquid detergents in some countries (which benefits competing surfactants), and by less consumer overdosing (particularly in North America with unit dose laundry products, assuming they continue to take some market share from traditional liquid detergents). However, consumption of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) will be positively affected in countries/regions such as India, China, Africa, and the Middle East, where powder detergents are still a very large part of the laundry detergent market.

Linear alkylbenzene sulfonate competes with several other major surfactants for use in household detergents. Some of the competitive surfactants have greater hard-water tolerance and better compatibility with enzymes and are milder than Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA). Historically, however, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) has most often been lower in cost and has had other more favorable properties compared with competing surfactants. During 2002-06, very high crude oil prices made Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) far less competitive than had been true in most years since its introduction. During 2007-11, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) prices tracked more closely those of the competitive surfactants. This led to a more stable pattern of consumption, even as prices for all surfactants continued to be very volatile. From late 2014 through 2017, low crude oil prices helped Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) become more competitive.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)/LAS production is impacted by the supply situation for competing products-mainly alcohol ether sulfates (AES). Shortages in AES supply or its high price has usually favored the use of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)/LAS. In the developing world, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) competes with soaps.

Alkylbenzene sulfonates are a class of anionic surfactants, consisting of a hydrophilic sulfonate head-group and a hydrophobic alkylbenzene tail-group. Along with sodium laureth sulfate they are one of the oldest and most widely used synthetic detergents and may be found in numerous personal-care products (soaps, shampoos, toothpaste etc.) and household-care products (laundry detergent, dishwashing liquid, spray cleaner etc.).[1] They were first introduced in the 1930s in the form of branched alkylbenzene sulfonates (BAS) however following environmental concerns these were replaced with linear alkylbenzene sulfonates (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)) during the 1960s.[2] Since then production has increased significantly from about 1 million tons in 1980, to around 3.5 million tons in 2016, making them most produced anionic surfactant after soaps.

Contents

1 Branched alkylbenzene sulfonates

2 Linear alkyl benzene Sulphonic Acid sulfonates

3 Structure property relationships

4 Environmental fate

5 References

Branched alkylbenzene sulfonates

An example of a branched alkylbenzene sulfonate (BAS)

Branched alkylbenzene sulfonates (BAS) were first introduced in the early 1930s and saw significant growth from the late 1940s onwards,[3] in early literature these synthetic detergents are often abbreviated as syndets. They were prepared by the Friedel-Crafts alkylation of benzene with ‘propylene tetramer’ (also called tetrapropylene) followed by sulfonation. Propylene tetramer being a broad term for a mixture of compounds formed by the oligomerization of propene, its use gave a mixture of highly branched structures.[4]

Compared to traditional soaps BAS offered superior tolerance to hard water and better foaming.[5] However, the highly branched tail made it difficult to biodegrade.[6] BAS was widely blamed for the formation of large expanses of stable foam in areas of wastewater discharge such as lakes, rivers and coastal areas (sea foams), as well as foaming problems encountered in sewage treatment[7] and contamination of drinking water.[8] As such BAS was phased out of most detergent products during the 1960s, being replaced with linear alkylbenzene sulfonates (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)). It is still important in certain agrochemical and industrial applications, where rapid biodegradability is of reduced importance.

Linear alkylbenzene sulfonates

An example of a linear alkylbenzene sulfonate (LAS)

Linear alkylbenzene sulfonates (LAS) are prepared industrially by the sulfonation of linear alkylbenzenes (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)), which can themselves be prepared in several ways.[2] In the most common route benzene is alkylated by long chain monoalkenes (e.g. dodecene) using hydrogen fluoride as a catalyst.[9] The purified dodecylbenzenes (and related derivatives) are then sulfonated with sulfur trioxide to give the sulfonic acid.[10] The sulfonic acid is subsequently neutralized with sodium hydroxide.[1] The term “linear” refers to the starting alkenes rather than the final product, perfectly linear addition products are not seen, in-line with Markovnikov’s rule. Thus, the alkylation of linear alkenes, even 1-alkenes such as 1-dodecene, gives several isomers of phenyldodecane.[11]

Structure property relationships

Under ideal conditions the cleaning power of BAS and Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is very similar, however Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) performs slightly better in normal use conditions, due to it being less affected by hard water.[12] Within Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) itself the detergency of the various isomers are fairly similar,[13][14] however their physical properties (Krafft point, foaming etc.) are noticeably different.[15][16] In particular the Krafft point of the high 2-phenyl product (i.e. the least branched isomer) remains below 0 °C up to 25% Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) whereas the low 2-phenyl cloud point is ∼15 °C.[17] This behavior is often exploited by producers to create either clear or cloudy products.

Environmental fate

Biodegradability has been well studied,[6][18][19] and is affected by isomerization, in this case, branching. The salt of the linear material has an LD50 of 2.3 mg/liter for fish, about four times more toxic than the branched compound; however the linear compound biodegrades far more quickly, making it the safer choice over time. It is biodegraded rapidly under aerobic conditions with a half-life of approximately 1-3 weeks;[18] oxidative degradation initiates at the alkyl chain.[1] Under anaerobic conditions it degrades very slowly or not at all, causing it to exist in high concentrations in sewage sludge, but this is not thought to be a cause for concern as it will rapidly degrade once returned to an oxygenated environment.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear Alkyl Benzene Sulphonic Acid

Product Information

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid is a chemical which is colorless and have viscous properties. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene sulphonic acid mainly using in detergent formulations. It is one of the most important and cheapest surfactants in powder formulation and detergent fluids. It has excellent cleansing properties.

Usages of Linear Alkyl Benzene Sulphonic Acid

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear Alkyl Benzene sulphonic acid is a batch of organic sulfur compounds that are used in most home detergents, dishwashing detergents, detergent powder, cleaning powder, washing powders, detergent cake, liquid soap, soaps etc. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), sulfonic acid compound is used as a foaming agent, cleaning agent in more formulations and toilet soaps for foaming.

Sulfonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is using in detergent industries, in textile industry as a washing agent, pesticides industries to improve the quality of spray. Sulfonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is not inflammable substance and can dissolve in water, but not in organic solvent.

Application of Linear Alkyl Benzene Sulphonic Acid

Linear alkyl benzene Sulphonic Acid used in the industry to increase the contact of polar and non-polar phases, such as oil, water, or water and minerals. Linear alkyl benzene Sulphonic Acid sulfonate is mainly used for the manufacture of household detergents such as laundry powder, washing liquid, dishwashing liquid and other household cleaners and other industrial uses. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid uses in produce sulfonic acid. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is an additive as a lubricating agent oils and have as corrosion and rust prevention. his product is a very effective intermediate surfactant.

Characteristics of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid packing

Basekim Chemical Production can supply Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid with drum. Each drum can take 220 kg and 80 drum can easily load in a container. It also depends on customer demands as well.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid is a chemical which is colorless and have viscous properties. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid mainly using in detergent formulations. It is one of the most important and cheapest surfactants in powder formulation and detergent fluids. It has excellent cleansing properties.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid in the formulation of anionic, non-anionic, and amphoteric surfactants, and it is extremely important for its degradability in nature. It is soluble in water and emulsifying agent. Linear Alkyl benzene sulphonic acid is one of the most widely used anionic surfactants due to its low cost, high efficiency and biocompatibility due to its linear chain. This anionic surfactant has hydrophilic and hydrophobic groups. These are non-volatile compounds produced by the sulfonation process. These compounds consist of mixtures of carbon chains of 10 to 14 carbon lengths that are a phenyl group with a sulfonate group

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid application

The properties of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid depend on the length of the alkane chains that give them different functionality. Surfactants are used in the industry to increase the contact of polar and non-polar phases, such as oil, water, or water and minerals. Linear alkyl benzene Sulphonic Acid sulfonate is mainly used for the manufacture of household detergents such as laundry powder, washing liquid, dishwashing liquid and other household cleaners and other industrial uses. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid uses in produce sulfonic acid. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is an additive as an lubricating agent oils and have as corrosion and rust prevention. his product is a very effective intermediate surfactant. It is usually neutralized with alkali types and forms sulphonates used in different fields. This product can be used in acidic environments.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid packing

can supply Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid with drum . Each drum can take 220 kg and 80 drum can easily load in a container

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Linear alkyl benzene Sulphonic Acid PACKING

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Specification

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) properties:

Trade Name: Sulfonic Acid

COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS

LINEAR ALKYL BENZENE SULPHONIC ACIDS

SUMMARY REPORT (1)

1. Linear alkyl benzene sulphonic acids (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)) are anionic surfactants. Linear alkyl benzene sulphonic acids are a mixtures of benzene sulphonic acids containing linear alkyl chains of different lengths (C9: less than 1%, C10: 8 to 16%, C11: 26 to 38%, C12: 26 to 38%, C13: 15 to 27%

and longer than C13: less than 2.5%). The amount of linear alkyl benzene sulphonic acid in the products is 2% and these products are indicated for post-dipping or teat-spraying of dairy cows.

The average dose per teat is assumed to be about 1 ml of the product, which equals to 80 mg of linear alkyl benzene sulphonic acid per cow per milking.

Linear alkyl benzene sulphonic acids are commonly used as cleaning agents (household and personal care products). Linear alkyl benzene sulphonic acid is included as surface active agent in Commission establishing an inventory and a common nomenclature of ingredients employed in cosmetic products. The occupational and environmental exposure to linear alkyl benzene sulphonic acid has been assessed by WHO in 1996: The worldwide consumption of linear alkyl benzene sulphonic acids in 1990 was about 2 million tonnes. Linear dodecyl benzene sulphonic acid, under the synonym sodium dodecyl benzene sulphonate, has been included in 1987 on the food additive list of the Food and Drug Administration (FDA) of the United States of America as a surface active agent in commercial detergents used in washing fruits and vegetables or to assist in lye peeling these products. The tolerance limit has been set on equal to or less than 0.2% in wash water.

2. Hydrophobic and hydrophilic groups of the molecule are both essential for action of surfactants in detergents. According to a published study on the in vitro germicidal activity of teat dips the linear alkyl benzene sulphonic acid-containing product (1.94%) was shown to be completely effective against suspensions of Escherichia coli, Staphylococcus aureus and Streptococcus agalactiae containing bacteria/ml each following a contact time of 2 minutes.

According to a published review document on in vitro studies, the 50% haemolytic concentration for linear alkyl benzene sulphonic acid was 9 mg/l and the 50% inhibitory concentration for prothrombin time was 0.05 mmol/l (16.3 mg/l). Linear alkyl benzene sulphonic acid influenced the thermal denaturation of proteins in vitro indicating protein-linear alkyl benzene sulphonic acid interaction.

3. Pharmacokinetic data are presented based on published reports. In rats, 14C-labelled alkyl benzene sulphonate was administered daily in the diet at a concentration of 1.4 mg/kg feed (dose per kg bw not given) to 12 male Wistar rats (120 to 140 g) for 5 weeks. Radioactivity was mostly excreted in faeces (52%) and in urine (29%) during the 5-week feeding period. After a single intraperitoneal administration of 14C-labelled alkyl benzene sulphonate (384.7 µg/rat), 85% of the dose was excreted during the first 24 hours and 95% within 10 days follow-up period. The main elimination route was via urine (50% of radioactivity), while 35% was excreted into faeces. However, during days 2 to 10 the percentage of radioactivity excreted into faeces was higher than that excreted into urine. No parent compound could be detected in faeces or urine but radioactivity was found in polar metabolites which were not further characterised. In another study, 35S-labelled linear alkyl benzene Sulphonic Acid was administered to male albino rats (Charles River strain, 150 to 200 g bodyweight) as a single per oral dose of 0.6, 1.2, 8 and 40 mg/rat (3 to 5 rats/group). During the 3-day follow-up period, 40 to 58% of radioactivity was excreted in urine and 39 to 56% in faeces. In faeces, the proportion of parent compound was 19% of total radioactivity. About 70% of linear alkyl benzene Sulphonic Acid was absorbed after oral administration. Two urine metabolites chemically close to methyl 4-(4′-methylsulfophenyl)- pentanoate were identified and were found to be a mixture of sulfophenyl butanoic acids and sulfophenyl pentanoic acids. Decomposition of linear alkyl benzene Sulphonic Acid sulphonate in rats was suggested to occur by ϖ-oxidation followed by catabolism through a β-oxidation mechanism. In vitro studies have not shown any penetration of 14C-labelled linear alkyl benzene sulphonic acid through intact rat or human skin. In in vivo studies in rats, 0.2 ml of 3 mM 14C linear alkyl benzene sulphonic acid (equivalent to 250 µg) was applied on 7.5 cm2 area of skin. These studies revealed deposition of 14C-labelled linear alkyl benzene sulphonic acid on the skin surface and in the upper regions of the hair follicles, however, no penetration of the substance could be detected after an exposure of 15 minutes.

4. The oral toxicity of linear alkyl benzene sulphonic acid is not very high. LD50 values for rats and mice range from 404 to 1525 mg/kg bw and 1575 to 1950 mg/kg bw, respectively. Both species showed diarrhoea and death occurred within 24 hours.

5. Repeated dose toxicity have been carried out using linear alkyl benzene sulphonic acids or their sodium salts containing alkyl chains of different lengths. Repeated dose toxicity has been documented on rats using 5 published articles, one of which was done in rats (60 females and 60 males/group) using only 1 dose level (0 and 100 mg of linear alkyl benzene sulphonic acid (chain length varying between C10 to C14)/l drinking water for 100 weeks). No differences were seen between test and control groups. No NOEL can be established due to deficiencies in the study design.

Wistar rats (about 150 g, 10 per sex and group) received the test product (dishwashing detergent containing linear alkyl benzene sulphonic acid) was mixed into drinking water at corresponding to 0, 0.015, 0.075 and 0.375 ml linear alkyl benzene sulphonic acid/kg bw for 6 months. In the 3rd

group the dose was increased after 9 weeks to 0.563 and again after 8 weeks to 0.75 ml/kg bw for 9 weeks. No differences were seen in haematological urine examinations between control and treated animals. Males showed decreased weight gain in the 3rd dose group, but the change was reversible once the treatment was stopped. Organ weights of the third group animals (5 per sex) killed immediately after the treatment were lower than those of the controls. Only control and the 3rd treatment groups were examined histologically. The animals in 3rd treatment group had small petechial bleedings (kidney, myocardium, lungs) and mucosal necrotis spots in gastrointestinal canal. They also had massive atrophy in adrenal glands and some atrophy in thymus. It is not possible to assess if changes showed correlation with dose or not, because only highest group was studied. No NOEL can be drawn from the study due to limited data available. Albino rats (FDRL strain, 15 animals per sex and group) received linear alkyl benzene sulphonic acid in feed at 0, 50 and 250 mg/kg bw for 12 weeks. Growth responses and food intake, haematological and urinary examinations showed no abnormalities. Histological findings revealed no abnormalities in lower dose group compared with control. Females in higher dose group had higher liver weight to body weight ratio than controls (p<0.01). The lower dose-group of 50 mg/kg bw/day showed no treatment-related changes. No NOEL can be established due to limited data available.

Sprague-Dawley rat (10 animals per sex and group) received linear alkyl benzene sulphonic acid in feed (0, 0.02, 0.1 and 0.5%) for 90 days (corresponding to 8.8, 44 and 220 mg/kg bw). No statistically significant differences were seen in weight gains, food utilisation, haematological and urinary examinations. Organ to body ratios as well as macroscopic and microscopic findings were comparable in treated and control groups. No NOEL can be established due to limited data available.

Charles River rat (50 animals per sex and group) received linear alkyl benzene sulphonic acid in feed (0, 0.02, 0.1 and 0.5%) for 2 years (dose per kg bw is not given). No statistically significant differences were seen in weight gains and food utilisation during the first 12 weeks. Organ to body ratios did not show any statistically significant differences when control and highest dose group were compared. At 8 months, male rats in 0.02 and 0.1% group had lower liver weight to bw ratios but this was not seen at later time points and never in the highest dose group. Haematological examinations revealed no treatment related changes. No abnormal macroscopic findings were seen and microscopic findings did not differ between the groups. No NOEL can be established due to limited data available. The highest dose (0.5% in feed for 2 years) did not show any treatment-related changes.

A published repeated dose toxicity study has been carried out using 6 to 7 months old Beagle dogs (2 animals per sex and group). A linear alkyl benzene sulphonic acid-containing product (15% linear alkyl benzene sulphonic acid) was administered in doses of 0, 10, 100 and 1000 mg/kg bw daily for 6 months by gavage (corresponding to 0, 1.5, 15, and 150 mg linear alkyl benzene sulphonic acid/kg bw). Lowest dose group showed no treatment-related changes. One female dog in middle dose level group had drooling from the second week forward and one animal regurgitated part of one dose which lead to sedation and decreased appetite. In the highest dose group, 3 to 4 animals had marked salivation. No animals died. In the highest dose group feed intake was moderately reduced. Marked reduction in weight gain was only seen in the highest dose group (more pronounced in females). No changes were seen in blood and urinary tests. Eyes and hearing were normal in all groups. In highest dose group mucosal erosions were found in stomach (mainly in cardia) of one male and one female. Presence of haemosiderosis in spleen was more pronounced in highest dose group. One dog in the same group had small necroses in pancreas and 2 dogs had some iron-free pigment in kidneys. No NOEL can be established due to small number of animals and limited data available. According to a WHO report, minimal effects, including biochemical and histopathological changes in the liver, have been reported in subchronic studies in which rats were administered linear alkyl benzene sulphonic acid in the diet or drinking water at concentrations equivalent to doses greater than 120 mg/kg bw per day. These changes appeared to be reversible. In the absence of the original data, no firm conclusion on the data reported in the WHO report can be drawn.

6. Tolerance in dairy cows was studied using commercial teat dip containing 2% linear alkyl benzene sulphonic acid. The product was used post-milking twice daily for 10 days. The product was well-tolerated.

7. Effects on reproduction have been documented using 2 published articles, one of which described a study in rats (10 females and 10 males/group) using only one dose level of linear alkyl benzene Sulphonic Acid sulphonic acid (0 and 100 mg/l drinking water). The data provided are too limited for the assessment.

Charles River rat (20 males and 20 females/group) received linear alkyl benzene sulphonic acid in feed (0, 0.02, 0.1 and 0.5% daily) in the 3-generation study (dose per kg bw is not given). No gross abnormalities were noted in pups. Rats of the F1 and F2 generations had similar growth patterns and organ to body weight ratios in control and test groups. No abnormalities were seen in histological examinations. In haematological studies, a statistically significant difference (level of significance not indicated) was seen in red blood cell count between control and females of highest test group. F3-weanlings were normal with respect to growth, organ to body weight ratios, macroscopic and microscopic examinations. Haematological values showed no treatment related trend or pattern in this study. The studies provided showed no indication of any reproduction toxicity.

8. Teratogenicity data were available from studies conducted using different linear alkyl benzene Sulphonic Acid sulphonic acids in mouse, rat and rabbit using oral, dermal and subcutaneous administration published in five articles. In two mouse studies the exposure times are not in accordance with the present guidelines. One study in mouse using dermal or subcutaneous administration was carried out using smaller group sizes and exposure times other than recommended in present guidelines. Linear alkyl benzene sulphonic acid (0, 0.2, 2, 300 and 600 mg/kg bw daily) was administered orally to female mice (n = 20), rats (n = 20) (days 6 to 15 of gestation) and rabbits (n = 13) days 6 to 18 of gestation). In all species primary toxic effects in dams were generally associated with disturbance of the gastrointestinal tract (diarrhoea, anorexia, retarded weight gain, weight loss, death). Rabbits were found to be the most susceptible species followed by mice and rats. The two highest dose groups showed maternal toxicity in mice and rabbits resulting in increased foetal loss and reduced litter size. No effects were seen in dams at 2 mg/kg bw in mice and rabbits. In rats, the highest dose caused maternal toxicity also, but did not affect litter parameters. No dose-related trend was seen in foetal weights. No difference was seen in number of major malformations between treated groups and controls. In mice, minor skeletal abnormalities increased to 33.7% in 300 mg/kg bw group compared with 11.7 to 13.3% in controls and lower dose groups. No teratological changes different from controls were seen except an increase in minor skeletal anomalies in 300 mg/kg bw group in mice. From the highest dose group no viable young were available as a result of marked maternal toxicity.

When dermal exposure (linear alkyl benzene sulphonic acid in water) was used in mouse, rat and rabbit, the two highest doses caused severe skin reactions in mice (50 and 500 mg/kg bw) and rabbits (9 and 90 mg/kg bw). The highest dose in rats (60 mg/kg bw) showed also skin irritation: erythema and oedema with peak response on days 4 to 5. Except for the highest dose group in mice, no treatment related effects were seen in dams and litter data. In mice, a significant (p<0.05) increase in embryonic deaths was seen at 50 and 500 mg/kg bw compared with controls. In rats, no significant changes in litter parameters were seen in treated animals. In rabbits, the highest dose group had somewhat higher foetal loss and smaller litter size (statistically not significant). No statistically significant differences in anomalies were seen. The studies provided showed no indication of any teratogenic potential of the substance. 9. When linear alkyl benzene sulphonic acids (C10 to C14) were used (22.2% solution of linear alkyl benzene sulphonic acid, 10 to 200 µl/plate) no mutagenicity was noted in an in vitro test using Salmonella typhimurium TA100 and TA98 assays with and without metabolic activation.

10. No formal carcinogenicity study has been carried out. Published long-term toxicity studies using linear alkyl benzene sulphonic acids have not shown increase in malignancies. Linear alkyl benzene Sulphonic Acid sulphonic acids are not considered to have carcinogenic potential.

11. Ten strains of Escherichia spp. (Escherichia coli) (also aerobic MIC), Bifidobacterium spp, Bacteroides spp. (Bacteroides fragilis), Eubacterium spp, Clostridium spp, Streptococcus spp, Fusobacterium spp, Lactobacillis spp., Proteus spp. and Peptostreptococcus spp. isolated from human faeces had MIC50 and MIC90 values for all species greater than 128 µg/ml in the agar-dilution assay. Bacterial species in human gut are not susceptible for linear alkyl benzene sulphonic acid.

12. The MIC-values for linear alkyl benzene sulphonic acid in milk for Lactobacillus acidophilus, Lactobacillus rhamnosus and Lactobacillus paracasei was 1.56 µg/ml, for Lactobacillus bulgaricus 0.39 µg/ml and for other Lactobacillus species tested and for Streptococcus thermophilus

0.0078 µg/ml. The study protocol does not define the concentration range studied. Therefore, it is not clear if the lowest MIC values (0.0078 µg/ml) are equal to the lowest concentration tested. In the second study effect of linear alkyl benzene sulphonic acid on dairy cultures was tested by measuring the effect on pH in cultures. The NOEL for Lactococcus lactis subsp. lactis was 4 µg/ml. The NOELs were higher for other bacterial species tested (Lactococcus. lactis subsp. cremoris, Lactococcus lactis subsp.lactis biovar diacetylactis, Leuconostoc mesenteroides subsp. cremoris or subsp. dextranicum, Bifidobacterium bifidum, Bifidobacterium longum, Streptococcus thermophilus, Lactobacillus Helveticus, Lactobacillus Delbrueckii subsp. bulgaricus, Lactobacillus Delbrueckii subsp. lactis and Lactobacillus acidophilus). Dairy cultures were not susceptible to linear alkyl benzene sulphonic acid concentrations present in milk.

13. Based on a published review document, batch tests show that human skin can tolerate contact with solutions containing up to 1% linear alkyl benzene sulphonic acid. No sensitisation was induced by linear alkyl benzene sulphonic acid to volunteers.

14. Human and environmental exposure has been assessed by WHO in 1996. In the absence of the original data, no firm conclusion on the data reported in the WHO report can be drawn.

15. Based on limited data available, daily exposure to linear alkyl benzene sulphonic acids in general in humans has been estimated to be about 5 mg/person in which the primary route of human exposure is assumed to be through dermal contact and to a lesser extent from the ingestion via drinking water and as a result of residues on utensils and food originating from cleaning agents and personal care products.

16. Due to lacking information and insufficiencies in the studies provided it was not possible to establish NOELs and calculate an ADI for linear alkyl benzene sulphonic acid. However, considering that

• toxicity has been only seen on high dose levels in all studies available

• no positive findings have been reported in mutagenicity studies

• long-term studies have not shown carcinogenic effects,

the CVMP considered that further toxicity studies were not necessary and that the linear alkyl benzene sulphonic acids residues in foodstuffs of animal origin would not raise a risk for human consumer.

17. Absorption was studied in 8 cows treated post-milking with commercial teat dip containing 2% linear alkyl benzene sulphonic acid for 10 days. Plasma samples were taken once a day at days 2, 4, 6, 8 and 10 just before milking during treatment and at days 2, 3, 4 and 5 after the end of

treatment. Linear alkyl benzene sulphonic acid concentrations were measured by a validated HPLC/fluorescence method with a limit of detection of 35 µg/l and a limit of quantification of 50 µg/l. The method has shown to be linear in plasma at concentration range of 50 to 500 µg/l. Linear alkyl benzene sulphonic acids were not detected in plasma samples except in two samples (125 µg/l and 53 µg/l). It is concluded that linear alkyl benzene sulphonic acids do not absorb through skin in great extend into blood circulation when used for post-dipping.

18. Residues in milk of 8 cows treated post-milking with commercial teat dip containing 2% linear alkyl benzene sulphonic acid by teat dipping for 10 days were determined. Milk samples were taken before milking for analysis at days 2, 4, 6, 8 and 10 during treatment and at days 2, 3, 4 and 5 after the end of treatment. Linear alkyl benzene sulphonic acid concentrations were measured by a validated HPLC/fluorescence method with a limit of detection of 30 µg/l and a limit of quantification of 100 µg/l. The method has shown to be linear in milk at concentration range of 100 to 4000 µg/l. During the treatment, residues were in the range of less than 30 µg/l to 208 µg/l. In most of the samples the concentration was below the limit of detection or the limit of quantification. After the end of treatment residue concentrations in milk were below the limit of quantification except in one milking of one cow at day 2 after the end of treatment showing a concentration of 344 µg/l which could be caused by external contamination.

Conclusion and recommendation

Having considered the criteria laid down by the Committee for Veterinary Medicinal Products for the inclusion of substances in Annex II of Council Regulation (EEC) No 2377/90 and in particular that:

• toxicity has been only seen on high dose levels in all studies available ,

• no teratogenic effects have been reported,

• no positive findings have been reported in mutagenicity studies,

• long-term studies have not shown carcinogenic effects,

• there was no susceptibility of human gut bacteria up to a dose of 128 µg/ml in vitro,

• there was no effect on relevant dairy cultures in concentrations up to 4 µg/ml,

• systemic bioavailability of linear alkyl benzene sulphonic acids after application to the teat appears to be negligible,

• even maximum residue concentrations observed in milk were well below any dose levels or concentration at which toxicological or microbiological effects may be expected; the Committee for Veterinary Medicinal Products concludes that there is no need to establish an MRL for linear alkyl benzene sulphonic acids and recommends its inclusion in Annex II of Council Regulation (EEC) No 2377/90 in accordance with the following table: Pharmacologically active substance(s)

Abeson is an anionic surface active agent with superior detergency and compatibility with a broad range of other anionic, nonionic and amphoteric surfactants. It is highly efficient versatile surfactant suitable for use separately as detergent in acidic environments.

As intermediate it is usually neutralized with various bases to produce sulfonates that are used in numerous industries, most commonly in the production of liquid and powder detergents, household and I&I cleaners, laundry detergents, dishwashing liquids, car wash products, hard surface cleaners etc. Besides these Abeson is applied in various industrial applications such as agriculture, emulsion polymerization, oil field chemicals etc.

Description

Synonyms LAS;Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA);LABS;Laurylbenzenesulfonic Acid;Laurylbenzenesulfonate;Linear Alkyl benzene Sulphonic Acid;DDBSA;Dodecyl Benzene Sulphonic Acid;Dodecyl Benzene Sulfonic Acid

Linear alkyl benzene sulphonic acid, also known as Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is a synthetic chemical surfactant, which is a widely used industrial detergent. It is used in washing powder, detergent powder, oil soap, cleaning powder and detergent cake.

DESCRIPTION

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is an anionic surfactant, whose molecules are characterized by a hydrophilic and a hydrophobic group. This nonvolatile chemical compound is synthesized through the process of sulfonation. The sulfonation reagents include sulfuric acid, chlorosulfonic acid, sulfamic acid and diluted sulfur trioxide.

The properties of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), differs in chemical and physical properties based on the length of the alkyl chain. This results in formulations, which finds many applications. The resulting surfactants are used in the chemical industry to improve contact between water and minerals.

USES

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is chiefly used in the detergent industry for the manufacture of washing powder, detergent powder, detergent cake, liquid soap, oil soap, scouring bar and cleaning powder. This chemical finds applications in anionic specialty formulations. The quality of pesticide sprays can be improved from it.

Linear alkyl benzene sulphonic acid is used as a washing and mercerizing agent in the textile industry. The surface area of distempers is increased using Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA). It is used as a wetting agent as well as an emulsifier in small quantities along with other surfactants, for foaming of toilet soaps.

Owing to its high active matter content and miscibility with low salt content and water, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in the polymerization of emulsions and in production of coupling agents, emulsifiers, agricultural herbicides, household and industrial cleaners.

ENVIRONMENTAL AND SAFETY CONSIDERATIONS

Most anionic surfactants including Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are nontoxic in nature. However, prolonged exposure to these surfactants, could irritate and damage the skin through the disruption of the lipid membrane, which protects the skin and other cells. On the other hand, the biodegradability is determined by surfactant’s hydrophobic hydrocarbon group.

ADVANTAGES

Linear Alkyl Benzene Sulphonic Acid is one of the largest synthetic surfactants by volume due to its low cost and high performance. Apart from this, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) can be dried to a stable powder form. This chemical is biodegradable and environmentally friendly.

Buy excess stock of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) for a discounted price.

Product Description

Linear Alkyl Benzene Sulphonic Acid

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 90% is the largest-volume synthetic surfactant because of its relatively low cost, good performance, the fact that it can be dried to a stable powder and the biodegradable environmental friendliness. LAB Sulphonic Acid is an anionic surfactant widely used in formulation of all ranges of Domestic Detergents Powder ,Cake & Dish wash cleaners. Due to its high active matter , miscibility with water and low salt content , it is also used in formulation of Industrial & Household liquid cleaners as well as in numerous industrial applications like as a coupling agent and as an emulsifier for agricultural herbicides and in emulsion polymerization.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 90% – Soft Acid Slurry is main raw material for:

Synthetic detergent industries in formulation of Washing powder, Detergent powder, Detergent cake, Liquid Soap, Cleaning powder, Scouring Bar, Oil soaps etc.

It is used in anionic specialty formulations

In other industries such as textile industries, it is used as an mercerising or washing agent

It is used to increase the surface area of distempers

As main active matter in all forms of Detergents like Cake, Powder and Liquid formulations

As emulsifier and wetting agent in small quantity with other surfactants in Toilet soaps for foaming

In Pesticides to improve the quality of spray

Cost Factor

Cost of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 90% Sulphonation Plant is 1/10th as compared to Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 96 % Sulphonation plant thereby giving huge cost advantage as a result of which Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 90% can be offered to consumers at competitive prices vis-a-vis Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 96%

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 90 % has 5-6 % Free Acid which is converted to Glauber Salt (Sodium Sulphate) on reaction with Soda Ash which is the common ingredient for all Detergent Powders. This Glauber Salt helps in keeping End Product i.e Detergent Powder free flowing and imparts anti-caking properties which is absent in Detergents formulated with Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 96 %

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is a largest volume surfactant because of its low cost, good performance; environmental friendliness .For the production of Linear Alkyl Benzene sulphonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), alkaline benzene linear sulfation is usually used. Its components: linear alkyl benzene Sulphonic Acid, oxygen, sulfur and citric acid. (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA))

Linear Alkyl Benzene Sulphonic Acid| Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) used in:

Linear Alkyl Benzene Sulphonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is a batch of organic sulfur compounds that are used in most home detergents, dishwashing detergents, detergent powder, cleaning powder, washing powders, detergent cake, liquid soap, soaps etc. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), sulfonic acid compound is used as a foaming agent , cleaning agent in more formulations and toilet soaps for foaming. Linear Alkyl Benzene Sulphonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is using in detergent industries, in textile industry as a washing agent, pesticides industries to improve the quality of spray. Sulfonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is not inflammable substance and can dissolve in water, but not in organic solvent.

Definition Linear Alkyl Benzene Sulphonic Acid

Definition Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Exporting Destinations:

ATDM are exporting Sulphonic Acid to African, European, South American, East Asian countries.ATDM lead to packing and exporting to mention above destinations, under Iran authorization by the best Iranian Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) raw materials in accordance with standard. If you want the updated price for Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) or Linear Alkyl Benzene Sulphonic acid and knowing more about further details, please contact us.

Advantage of Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA):

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Excellent solubility even at low temperatures

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) has high power of foam

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is a biodegradable.

Linear Alkyl Benzene Sulphonic Acid application

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in produce cleansers, light detergent, hard detergent, Liquid Soap, Cleaning powder, Scouring Bar, Oil soaps etc.

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in produce various detergents and emulsifiers. It is used to increase the surface area of distempers

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in produce cleaner of textile industry such as washing powder.

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in produce industrial electronic, leather industry.

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used in produce paper-making industry.

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) can be used in produce detergent of dishware.

Linear Alkyl Benzene Sulphonic Acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is used to produce Linear Alkyl Benzene Sulphonic Acid sodium.

Warning Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), Linear Alkyl Benzene Sulphonic Acid

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), Linear Alkyl Benzene Sulphonic acid is capable of causing eye, skin and lung irritation as well as burns in extreme cases. Thus, occupational exposure limits should be implemented for safe industrial practices. When you work with sulfonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), you must be caring you. Same as workplace that make use of Linear Alkyl Benzene sulphonic acid, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) should have enclosed operations with the use of local ventilation or exhaust to release the chemicals. You should be attention to warning information at the work area to communicate all the safety about this corrosive element.

Linear Alkyl Benzene Sulphonic Acid Product description

CAS No.: 27176-87-0

Synonyms: Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA); Laurylbenzenesulfonic Acid;

Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid

Linear Alkyl Benzene Sulphonic Acid is a synthetic surfactant with a wide range of applications like as a coupling agent, as an emulsifier and in the production of household detergents.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 96% Linear Alkyl Benzene Sulphonic Acid DBSA For Laundry soap detergent

Description:

it is a kind of weak organic acid and easy to dissolve in water. Widely used in washing powder, civil detergent cleanser and industrial detergents

96% active content,brown liquid ,must be neutralized by hydroxyl sodium when use it .

Industrial applications of wetting agent, emulsifier for agricultural herbicides and in polymerization

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 96% CAS No. 27176-87-0

Detergent Chemical: Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 96% CAS No. 27176-87-0 /

Application

[1] Used as raw material for washing powder, laundry detergent and industrial detergent.

[2] can be used as a curing catalyst for amino baking varnish, used to prepare various liquid and solid detergents.

[3] It is used for the production of linear alkylbenzene sulfonate sodium salt, ammonium salt and ethanolamine salt. It is the main raw material for the production of detergents, household liquid detergents, industrial detergents and other common detergents.

Its components: linear alkyl benzene Sulphonic Acid, oxygen, sulfur and citric acid. Linear alkyl benzene sulphonic acid is prepared commercially by just sulfonating linear alkylbenzene (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)).Linear alkyl benzene sulphonic acid which is mainly called (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)), the worlds largest volume synthetic surfactant, which includes the various salts of sulfonated alkylbenzenes, which is widely used in household detergents as well as in numerous industrial application. We, New India Detergents Ltd. Group of Companies are engaged in manufacturing of Linear Alkyl Benzene Sulphonic Acid (Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) 90% ) since 20 years and have grown to be a leader in its area of operations, adhering to the quality standards and catering to the domestic & global markets.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) .

Product Name Dodecylbenzene sulfonic acid, mixture of C10-C13 isomers Cat No. benzene sulfonic acid, sodium salt Category Name Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) Structural Formula Call a …

INTRODUCTION:

This project profile in detail foresees setting up of unit to produce ACID SLURRY

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) have been the major surfactant used in detergents for more than thirty years and continues to represent a substantial portion of the surfactants market today. Supporting this history of safe usage is a large archive of environmental research that has been conducted on Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA). This environmental research, performed by top environmental scientists and research agencies, has investigated virtually every part of the environment that could have been exposed to Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA). The studies have repeatedly proven Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) environmental acceptability and safety.

Because of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA)’s environmental safety, cleaning effectiveness and cost competitiveness, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) has experienced 30 years of ever-increasing use around the world.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), the material used to produce Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), is derived exclusively from petroleum bi-products–benzene and paraffin derived from kerosene. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) currently represents one-third of the active ingredients in detergents worldwide.

Linear alkyl benzene Sulphonic Acid is the raw material used to manufacture Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA), an active ingredient in the formulation of detergents. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) eliminate dirt by its physicochemical mechanism and it is one of the surfactants most widely used in liquid cleaners and in powder. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) have been used for more than 25 years in the manufacture of detergents and it is known for its excellent quality/price ratio.

BASIS AND PRESUMPTIONS: –

1. Single shift of 8 hours a day, 25 days a month and 300 days in a year is presumed. Efficient machines and workers are also presumed.

2. Minimum 2 year period is considered for achieving full capacity utilization

3. Labour rates are as per the prevailing rates.

4. An average interest rate of 14% is considered.

5. The estimates are drawn for a production capacity generally considered techno-economically viable for model type of manufacturing activity.

6. The information supplied is based on a standard type of manufacturing activity viable for model type of manufacturing activity.

7. The information supplied is based on a standard type of manufacturing activity utilizing conventional techniques of production at optimum level of performance.

8. Costs in machinery and equipment, raw materials and the selling prices of the finished products etc., are generally prevailing at the time of preparation of the project profiles and may vary depending upon various factors.

9. Whereas some names of manufacturers, suppliers of machinery and equipment, raw materials etc. are indicated at the end of the profile, those are by no means exclusive or exhaustive.

IMPLEMENTATION SCHEDULE: –

Derivation Linear Alkyl benzene Sulphonic Acid, S

Raw material consumption per tones of 85-88% acid slurry is Linear alkyl benzene Sulphonic Acid 700-750 kg, Sulphonating agent 20% oleum 800-900 kg, 98% sulphuric acid 1100-1200kg.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are anionic surfactants with molecules characterized by a hydrophobic and a hydrophilic group. Alpha-olefin sulfonates (AOS) alkyl sulfates (AS) are also examples of commercial anionic surfactants.

They are nonvolatile compounds produced by sulfonation.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are complex mixtures of homologues of different alkyl chain lengths (C10 to C13 or C14) and phenyl positional isomers of 2 to 5-phenyl in proportions dictated by the starting materials and reaction conditions, each containing an aromatic ring sulfonated at the Para position and attached to a linear alkyl chain at any position with the exception of terminal one (1-phenyl).

The properties of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) differ in physical and chemical properties according to the alkyl chain length, resulting in formulations for various applications.

The starting material Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) (linear alkyl benzene Sulphonic Acid) is produced by the alkylation of benzene with n-paraffins in the presence of hydrogen fluoride (HF) or aluminium chloride (AlCl3) as a catalyst. Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are produced by the sulfonation of Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) with oleum in batch reactors.

Other sulfonation alternative reagents are sulfuric acid, diluted sulfur trioxide, chlorosulfonic acid and sulfamic acid on falling film reactors.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) are then neutralized to the desired salt (sodium, ammonium, calcium, potassium, and triethanolamine salts).

Surfactants are widely used in the industry needed to improve contact between polar and non-polar media such as between oil and water or between water and minerals.

Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is mainly used to produce household detergents including laundry powders, laundry liquids, dishwashing liquids and other household cleaners as well as in numerous industrial applications like as a coupling agent and as an emulsifier for agricultural herbicides and in emulsion polymerization.

Because they are stable, Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) can be isolated, stored and shipped as an article of commerce.

SO3 is an aggressive electrophilic reagent that rapidly reacts with any organic compound containing an electron donor group.

Sulfonation is a difficult reaction to perform on an industrial scale because the reaction is rapid and highly exothermic; releasing approximately 380 kJ/kg SO3 (800 BTUs per pound of SO3) reacted.

Most organic compounds form a black char on contact with pure SO3 due to the rapid reaction and heat evolution.

Additionally, the reactants increase in viscosity between 15 and 300 times as they are converted from the organic feedstock to the Linear Alkyl Benzene sulphonic acid.

This large increase in viscosity makes heat removal difficult. The high viscosity of the formed products reduces the heat transfer coefficient from the reaction mass.

Effective cooling of the reaction mass is essential because high temperatures promote side reactions that produce undesirable by-products.

Also, precise control of the molar ratio of SO3 to organic is essential because any excess SO3, due to its reactive nature, contributes to side reactions and by-product formation.

Therefore, commercial scale sulfonation reactions require special equipment and instrumentation that allows tight control of the mole ratio of SO3 to organic and rapid removal of the heat of reaction.

Sulfuric acid (H2SO4) and oleum (SO3 ??H2SO4) are widely used as sulfonating agents.

Oleum is used to sulfonate alkyl benzene and sulfate fatty alcohols for heavy duty detergents.

It is an equilibrium process, as water is formed in the reaction and the resultant water dilutes the oleum and/or sulfuric acid.

The sulfonation reaction stops when the sulfuric acid concentration drops to approximately 90%.

Oleum sulfonation can be operated as either a batch or continuous process. This process has the dual advantage of low SO3 cost and low capital equipment cost.

However, it has the disadvantage of being an equilibrium process which leaves large quantities of un-reacted sulfuric acid. This waste acid must be separated from the reaction mixture and subsequently disposed.

Oleum and sulfuric acid can be used to sulfonate aromatics and alcohols in either batch or continuous equipment.

For detergent alkylates, the batch equipment is used which is a stirred, sealed, glass lined or stainless steel kettle with a provision for heating and cooling.

The detergent alkylate is first added to the reaction vessel then the oleum is slowly added over a period of several hours.

The reaction is highly exothermic and the oleum addition rate is determined by the ability to remove the heat of reaction.

The temperature should be maintained below 35°C for optimum product quality.

Frequently the heat of reaction is removed by pumping the reaction mixture through an external heat exchanger.

Because it is an equilibrium reaction, except for the special case of azeotropic sulfonation of hydrotropes with sulfuric acid, a large surplus of sulfuric acid forms.

When the sulfonation reaction is complete,the sulfuric acid may be separated from the sulfonated detergent alkylate by adding water.

The water addition (typically about 10% by weight of the reaction mixture) causes a phase separation to occur between the Linear Alkyl Benzene sulphonic acid and the diluted sulfuric acid.

The separation usually takes place in a separate, glass lined vessel and occurs over a period of about for 10 hours.

After separation, the Linear Alkyl Benzene sulphonic acid may be neutralized with aqueous sodium hydroxide, usually in a separate neutralization vessel.

Including neutralization, total batch time is 15 to 20 hours.

The product contains about 15% sodium sulfate after neutralization if the acid is separated, and about 60% sodium sulfate if not. Without separation, the product’s application is limited to low active, traditional detergent powders where the large content of sodium sulfate is used as a filler.

Sulphonator:

Several types of commercial sulfonators are available.

Film reactors are the most common in detergent processing for consumer products, especially to produce cosmetic quality materials from oleo chemical feed stocks.

In a film reactor, the organic feedstock is extruded onto the wall of the reactor (reaction surface) as a continuous film.

Organic feed rate to the reactor vessel is measured by a highly accurate mass flow meter and controlled by a variable speed driven gear pump.

The proper organic feed rate is based on the preset sulfur-to-organic mole ratio. The SO3, diluted with very dry air, flows over the film of organic material.

The SO3 diffuses into the organic film and reacts to form a Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA).

In almost all commercial reactors both the organic and SO3 flow concurrently from the top of the reactor to the bottom.

The heat of reaction is removed by cooling water, which flows through cooling jackets underneath the reaction surface of the reactor. Cooling jackets on the reactor remove most of the heat of reaction.

The product exiting the reactor is instantly quench cooled by removing the acid, pumping it through a heat exchanger to cool, then returning it to the bottom of the reactor.

This cooling process reduces the time that the Calcium LABSA (Calcium linear alkyl benzene sulphonic acid, Kalsiyum LABSA, CALCIUM LABSA) is held at an elevated temperature and results in better product quality.

Kalsiyum LABSA

SINIFLANDIRMA

Anyonik Yüzey Aktif Madde

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’NIN AÇIKLAMASI

Dorusal alkil benzen sülfonik asit, nispeten düük maliyeti, iyi performans, kararl bir toz halinde kurutulabilmesi ve düz zincire sahip olduu için biyolojik olarak parçalanabilir çevre dostu olmas nedeniyle en büyük hacimli sentetik yüzey aktif maddedir. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), hidrofobik ve hidrofilik bir grupla karakterize edilen molekülleri olan anyonik bir yüzey aktif maddedir. Alfa-olefin sülfonatlar (AOS) alkil sülfatlar (AS) da ticari anyonik yüzey aktif cisimlerinin örnekleridir. Sülfonasyonla üretilen uçucu olmayan bileiklerdir. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), farkl alkil zincir uzunluklarna sahip homologlarn (C10 ila C13 veya C14) ve 2 ila 5-fenilin fenil pozisyonel izomerlerinin, balangç materyalleri ve reaksiyon koullar tarafndan dikte edilen oranlarda, her biri para pozisyonunda sülfonatlanm bir aromatik halka içeren karmak karmlardr. ve terminal bir (1-fenil) haricinde herhangi bir pozisyonda bir dorusal alkil zincirine balanr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn özellikleri, alkil zincir uzunluuna göre fiziksel ve kimyasal özelliklerde farkllk gösterir ve çeitli uygulamalar için formülasyonlar salar. Balangç malzemesi Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), benzenin, katalizör olarak hidrojen florür (HF) veya alüminyum klorür (AlCl3) varlnda n-parafinlerle alkilasyonu ile üretilir. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), kesikli reaktörlerde LAB’nin oleum ile sülfonasyonu ile üretilir. Dier sülfonasyon alternatif reaktifleri, düen film reaktörlerindeki sülfürik asit, seyreltilmi sülfür trioksit, klorosülfonik asit ve sülfamik asittir. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) daha sonra istenen tuza (sodyum, amonyum, kalsiyum, potasyum ve trietanolamin tuzlar) nötralize edilir. Yüzey aktif maddeler, ya ve su veya su ve mineraller gibi polar ve polar olmayan ortamlar arasndaki temas iyiletirmek için ihtiyaç duyulan endüstride yaygn olarak kullanlmaktadr. Dorusal alkil benzen sülfonik asit esas olarak çamar tozlar, çamar svlar, bulak ykama svlar ve dier ev temizleyicileri dahil ev tipi deterjanlarn yan sra bir balama maddesi olarak ve tarmsal herbisitler için bir emülgatör olarak ve emülsiyon polimerizasyonunda çok sayda endüstriyel uygulamada kullanlr.

FZKSEL VE KMYASAL ÖZELLKLER

Çamar tozlar, çamar svlar, bulak ykama svlar ve dier ev temizleyicileri dahil ev deterjanlar. Islatma maddesinin endüstriyel uygulamalar, tarmsal herbisitler için emülgatör ve polimerizasyon.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), ticari olarak dorusal alkilbenzenin (LAB) sülfonatlanmasyla hazrlanr. Çeitli sülfonatl alkilbenzen tuzlarn içeren dünyann en büyük hacimli sentetik yüzey aktif maddesi olan Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), ev deterjanlarnda ve çok sayda endüstriyel uygulamada yaygn olarak kullanlmaktadr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) pazar, bata ev deterjanlar olmak üzere Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) pazarlar tarafndan yönlendirilmektedir. Dorusal alkilbenzen sülfonat, dorusal olmayan (dall) alkilbenzen sülfonat (BAS) için biyolojik olarak parçalanabilir bir ikame olarak gelitirildi ve dünya çapnda ev deterjanlarnda büyük ölçüde BAS’n yerini ald.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) tüketim modeli, Kuzey Amerika’da tüketicilerin sv çamar deterjanlarn çok fazla tercih ettiini gösterirken, Bat Avrupa, Japonya ve Çin’de tozlar baskn ürünler olmaya devam ediyor. Dier dünya bölgelerindeki karlatrlabilir ve güvenilir veriler genellikle mevcut deildir. Bu daha az gelimi dünya alanlarnda, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) esas olarak sadece çamar tozlarnda (özellikle Hindistan ve Endonezya’da) ve elde bulak ykama svlarnda kullanlmaktadr. kincisi genellikle genel amaçl temizleyiciler olarak kullanlr.

Aadaki pasta grafii dünya Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) tüketimini gösterir:

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn yaklak% 82-87’si, çamar tozlar, çamar svlar, bulak ykama svlar ve dier ev temizleyicileri dahil olmak üzere ev deterjanlarnda kullanlr. Dier uygulamalarn çounu endüstriyel, kurumsal ve ticari temizleyiciler oluturur, ancak Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) ayn zamanda bir emülgatör (örnein tarmsal herbisitler için ve emülsiyon polimerizasyonunda) ve bir slatma maddesi olarak kullanlr. Kiisel bakm uygulamalarnda da çok küçük hacimler kullanlmaktadr. Maliyet hususlar nedeniyle Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’dan alternatif yüzey aktif maddelere yönelik reformülasyonlar, enzimlerin daha fazla kullanlmas ve genel olarak daha düük sonuçlara yol açan olumsuz ekonomik koullar dahil olmak üzere çeitli gelimelerin sonucu olarak, Kuzey Amerika hanehalk segmentindeki talep 2000-11’de keskin bir düü gösterdi. deterjanlarda yüzey aktif madde seviyeleri. Ancak, tüketim 2011-17 arasnda sabitlendi.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) tüketimi, oldukça gelimi bölgelerde muhtemelen istikrar kazanacak veya biraz azalacaksa da, Orta Dou, Afrika, Hindistan ve Çin gibi baz daha az gelimi bölge veya ülkelerde ve bunun yan sra% 3,0-5,0 orannda artacaktr. Güneydou Asya. Asya Pasifik bölgesindeki Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) talebinin hzl büyümesinin bir sonucu olarak, bölgedeki talep 2017’de küresel talebin yarsndan fazlasn oluturdu.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn dünya çapndaki büyümesi, deterjan üreticilerinin yüzey aktif madde formülasyonlarndaki aktif içerii azaltma çabalarndan, baz ülkelerde sv deterjanlara geçiten (rakip yüzey aktif maddelere fayda salar) ve daha az tüketici doz amndan (özellikle de Geleneksel sv deterjanlardan biraz pazar pay almaya devam ettiklerini varsayarak, birim doz çamar ykama ürünleri ile Kuzey Amerika). Bununla birlikte, toz deterjanlarn hala çamar deterjan pazarnn çok büyük bir parças olduu Hindistan, Çin, Afrika ve Orta Dou gibi ülkelerde / bölgelerde Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) tüketimi olumlu yönde etkilenecektir.

Dorusal alkilbenzen sülfonat, ev tipi deterjanlarda kullanm için dier baz önemli yüzey aktif maddelerle rekabet eder. Rekabetçi yüzey aktif cisimlerinin bazlar daha sert su toleransna ve enzimlerle daha iyi uyumlulua sahiptir ve Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’dan daha hafiftir. Bununla birlikte, tarihsel olarak, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), çou zaman maliyet açsndan daha düük olmutur ve rakip yüzey aktif maddelere kyasla dier daha uygun özelliklere sahip olmutur. 2002-06 döneminde, çok yüksek ham petrol fiyatlar, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’y piyasaya sürülmesinden bu yana çou ylda olduundan çok daha az rekabetçi hale getirdi. 2007-11 döneminde, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) fiyatlar, rekabetçi yüzey aktif maddelerinkilere daha yakn bir ekilde izledi. Bu, tüm yüzey aktif maddeler için fiyatlar çok dalgal olmaya devam ederken bile daha istikrarl bir tüketim modeline yol açt. 2014’ün sonlarndan 2017’ye kadar, düük ham petrol fiyatlar, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn daha rekabetçi olmasna yardmc oldu.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) / LAS üretimi, bata alkol eter sülfatlar (AES) olmak üzere rakip ürünlerin tedarik durumundan etkilenir. AES tedarikindeki ktlk veya yüksek fiyat genellikle Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) / LAS kullanmn desteklemitir. Gelien dünyada, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) sabunlarla rekabet etmektedir.

Alkilbenzen sülfonatlar, bir hidrofilik sülfonat ba grubu ve bir hidrofobik alkilbenzen kuyruk grubundan oluan bir anyonik yüzey aktif maddeler snfdr. Sodyum lauret sülfat ile birlikte en eski ve en yaygn kullanlan sentetik deterjanlardan biridir ve çok sayda kiisel bakm ürününde (sabun, ampuan, di macunu vb.) Ve ev bakm ürünlerinde (çamar deterjan, bulak deterjan, sprey temizleyici) bulunabilir. vb.). [1] lk olarak 1930’larda dall alkilbenzen sülfonatlar (BAS) eklinde tantldlar, ancak çevresel kayglar nedeniyle bunlar 1960’larda dorusal alkilbenzen sülfonatlar (Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)) ile deitirildi. [2] O zamandan beri üretim, 1980’de yaklak 1 milyon tondan 2016’da yaklak 3,5 milyon tona çkarak sabunlardan sonra en çok üretilen anyonik yüzey aktif madde haline geldi.

çindekiler

1 Dall alkilbenzen sülfonatlar

2 Dorusal alkil benzen Sülfonik Asit sülfonatlar

3 Yap özellii ilikileri

4 Çevresel kaderi

5 Kaynaklar

Dall alkilbenzen sülfonatlar

Dall bir alkilbenzen sülfonat (BAS) örnei

Dall alkilbenzen sülfonatlar (BAS) ilk olarak 1930’larn balarnda tantld ve 1940’larn sonlarndan itibaren önemli bir büyüme gördü, [3] erken literatürde bu sentetik deterjanlar genellikle sendikalar olarak ksaltld. Benzenin ‘propilen tetramer’ (tetrapropilen olarak da adlandrlr) ile Friedel-Crafts alkilasyonu ve ardndan sülfonasyon yoluyla hazrlandlar. Propilen tetramer, propenin oligomerizasyonu ile oluan bileiklerin bir karm için geni bir terim olup, kullanm oldukça dall yaplarn bir karmn vermitir. [4]

Geleneksel sabunlarla karlatrldnda BAS, sert suya kar üstün tolerans ve daha iyi köpüklenme sundu. [5] Bununla birlikte, çok dall kuyruk biyolojik olarak parçalanmay zorlatrd. [6] BAS, göller, nehirler ve ky bölgeleri (deniz köpükleri) gibi atk su boaltma alanlarnda geni stabil köpük oluumlarnn yan sra kanalizasyon artmnda [7] ve içme suyunun kirlenmesinde karlalan köpüklenme sorunlarndan geni ölçüde sorumlu tutulmutur. [ 8] Bu nedenle BAS, 1960’larda çou deterjan ürününden çkarld ve yerini dorusal alkilbenzen sülfonatlar (Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)) ald. Hzl biyolojik bozunmann öneminin azald baz agrokimyasal ve endüstriyel uygulamalarda hala önemlidir.

Dorusal alkilbenzen sülfonatlar

Dorusal alkilbenzen sülfonat (LAS) örnei

Dorusal alkilbenzen sülfonatlar (LAS), endüstriyel olarak, kendileri birkaç yolla hazrlanabilen dorusal alkilbenzenlerin (Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)) sülfonasyonu ile hazrlanr. [2] En yaygn yoldan benzen, katalizör olarak hidrojen florür kullanlarak uzun zincirli monoalkenler (örn. Dodesen) ile alkillenir. [9] Saflatrlm dodesilbenzenler (ve ilgili türevleri) daha sonra sülfonik asit vermek üzere sülfür trioksit ile sülfonlanr. [10] Sülfonik asit daha sonra sodyum hidroksit ile nötralize edilir. [1] “Dorusal” terimi, nihai üründen ziyade balangç alkenlerine atfta bulunur, Markovnikov kuralna uygun olarak mükemmel dorusal ekleme ürünleri görülmez. Dolaysyla, dorusal alkenlerin, hatta 1-dodesen gibi 1-alkenlerin alkilasyonu birkaç fenildodekan izomerini verir. [11]

Yap özellii ilikileri

deal koullar altnda BAS ve Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn temizleme gücü çok benzerdir, ancak Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), sert sudan daha az etkilendii için normal kullanm koullarnda biraz daha iyi performans gösterir. [12] Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn kendi içinde çeitli izomerlerin temizleme gücü oldukça benzerdir, [13] [14] ancak fiziksel özellikleri (Krafft noktas, köpürme vb.) Belirgin ekilde farkldr. [15] [16] Özellikle yüksek 2-fenil ürününün (yani en az dallanm izomerin) Krafft noktas 0 ° C’nin altnda,% 25’e kadar Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’da kalrken, düük 2-fenil bulutlanma noktas ∼15 ° C’dir. Bu davran genellikle üreticiler tarafndan berrak veya bulank ürünler oluturmak için kullanlr.

Çevresel kader

Biyolojik bozunabilirlik iyi çallmtr [6] [18] [19] ve izomerizasyondan, bu durumda dallanmadan etkilenir. Dorusal malzemenin tuzu, balklar için 2.3 mg / litre LD50’ye sahiptir, bu, dall bileikten yaklak dört kat daha toksiktir; ancak dorusal bileik biyolojik olarak çok daha hzl bozunur ve bu da onu zaman içinde daha güvenli bir seçim haline getirir. Yaklak 1-3 haftalk yarlanma ömrü ile aerobik koullar altnda hzla biyolojik olarak bozunur; [18] Oksidatif bozunma alkil zincirinde balar. [1] Anaerobik koullar altnda çok yava bozunur veya hiç bozunmaz, bu da kanalizasyon çamurunda yüksek konsantrasyonlarda bulunmasna neden olur, ancak oksijenli bir ortama geri döndüünde hzla bozunaca için bunun bir endie nedeni olduu düünülmemektedir.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer Alkil Benzen Sülfonik Asit

Ürün Bilgisi

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer alkil benzen Sülfonik Asit, renksiz ve viskoz özelliklere sahip bir kimyasaldr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Esas olarak deterjan formülasyonlarnda kullanlan dorusal alkil benzen sülfonik asit. Toz formülasyon ve deterjan svlarnda en önemli ve en ucuz yüzey aktif maddelerden biridir. Mükemmel temizleme özelliklerine sahiptir.

Dorusal Alkil Benzen Sülfonik Asit Kullanm Alanlar

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer Alkil Benzen sülfonik asit, çou ev deterjan, bulak deterjan, deterjan tozu, temizlik tozu, ykama tozu, deterjan keki, sv sabun, sabun vb. köpük yapc, daha çok formülasyonda temizlik maddesi ve köpürtücü tuvalet sabunlar olarak kullanlr.

Sülfonik asit, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), deterjan endüstrisinde, tekstil endüstrisinde ykama maddesi olarak, pestisit endüstrisinde sprey kalitesini artrmak için kullanlmaktadr. Sülfonik asit, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) yanc deildir ve suda çözünebilir, ancak organik çözücü içinde çözülemez.

Dorusal Alkil Benzen Sülfonik Asit Uygulamas

Endüstride ya, su veya su ve mineraller gibi polar ve polar olmayan fazlarn temasn artrmak için kullanlan dorusal alkil benzen Sülfonik Asit. Dorusal alkil benzen Sülfonik Asit sülfonat, esas olarak çamar tozu, ykama svs, bulak deterjan ve dier ev temizleyicileri ve dier endüstriyel kullanmlar gibi ev tipi deterjanlarn üretiminde kullanlr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit, sülfonik asit üretiminde kullanr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), yalama maddesi yalar olarak bir katk maddesidir ve korozyon ve pas önleyici özelliklere sahiptir. onun ürünü çok etkili bir ara yüzey aktif maddedir.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn Özellikleri

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit paketleme

Basekim Kimya Üretim tamburlu Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer alkil benzen Sülfonik Asit tedarik edebilir. Her bir tambur 220 kg alabilir ve 80 varil bir konteynere kolaylkla yüklenebilir. Ayn zamanda müteri taleplerine de baldr.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer alkil benzen Sülfonik Asit, renksiz ve viskoz özelliklere sahip bir kimyasaldr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit esas olarak deterjan formülasyonlarnda kullanlr. Toz formülasyon ve deterjan svlarnda en önemli ve en ucuz yüzey aktif maddelerden biridir. Mükemmel temizleme özelliklerine sahiptir.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer alkil benzen Sülfonik Asit, anyonik, anyonik olmayan ve amfoterik yüzey aktif cisimlerinin formülasyonunda bulunur ve doada parçalanabilirlii açsndan son derece önemlidir. Suda ve emülsifiye edici maddede çözünür. Lineer Alkil benzen sülfonik asit, lineer zinciri sayesinde düük maliyeti, yüksek verimlilii ve biyouyumluluu nedeniyle en yaygn kullanlan anyonik yüzey aktif maddelerden biridir. Bu anyonik yüzey aktif madde hidrofilik ve hidrofobik gruplara sahiptir. Bunlar, sülfonasyon ilemi ile üretilen uçucu olmayan bileiklerdir. Bu bileikler, bir sülfonat grubu ile bir fenil grubu olan 10 ila 14 karbon uzunluunda karbon zincirlerinin karmlarndan oluur.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit uygulamas

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit’in özellikleri, onlara farkl ilevsellik salayan alkan zincirlerinin uzunluuna baldr. Yüzey aktif maddeler endüstride ya, su veya su ve mineraller gibi polar ve polar olmayan fazlarn temasn artrmak için kullanlr. Dorusal alkil benzen Sülfonik Asit sülfonat, esas olarak çamar tozu, ykama svs, bulak deterjan ve dier ev temizleyicileri ve dier endüstriyel kullanmlar gibi ev tipi deterjanlarn üretiminde kullanlr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit, sülfonik asit üretiminde kullanr. Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), yalama maddesi yalar olarak bir katk maddesidir ve korozyon ve pas önleyici özelliklere sahiptir. onun ürünü çok etkili bir ara yüzey aktif maddedir. Genellikle alkali çeitleri ile nötralize edilerek farkl alanlarda kullanlan sülfonatlar oluturur. Bu ürün asidik ortamlarda kullanlabilir.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit paketleme

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Lineer alkil benzen Sülfonik Asit’i tamburla tedarik edebilir. Her bir tambur 220 kg alabilir ve 80 varil bir konteynere kolayca yüklenebilir

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Dorusal alkil benzen Sülfonik Asit AMBALAJI

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) Spesifikasyonu

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) özellikleri:

Ticari Ad: Sülfonik Asit

VETERNER TIBB ÜRÜNLER KOMTES

LNEER ALKL BENZEN SÜLFONK ASTLER

ÖZET RAPORU (1)

1. Dorusal alkil benzen sülfonik asitler (Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)) anyonik yüzey aktif maddelerdir. Dorusal alkil benzen sülfonik asitler, farkl uzunluklarda dorusal alkil zincirleri içeren benzen sülfonik asitlerin bir karmdr (C9:% 1’den az, C10:% 8 ila 16, C11:% 26 ila% 38, C12:% 26 ila% 38, C13: % 15 ilâ 27

ve C13’ten daha uzun:% 2,5’ten az). Ürünlerdeki dorusal alkil benzen sülfonik asit miktar% 2’dir ve bu ürünler, süt ineklerinin sonradan daldrlmas veya meme ba püskürtülmesi için endikedir.

Meme bana ortalama dozun, her sam için inek bana 80 mg dorusal alkil benzen sülfonik aside eit olan yaklak 1 ml ürün olduu varsaylr.

Dorusal alkil benzen sülfonik asitler genellikle temizlik maddeleri (ev ve kiisel bakm ürünleri) olarak kullanlr. Dorusal alkil benzen sülfonik asit, kozmetik ürünlerde kullanlan bileenlerin bir envanteri ve ortak bir adlandrmas oluturan Komisyonda yüzey aktif ajan olarak dahil edilmitir. Dorusal alkil benzen sülfonik aside mesleki ve çevresel maruziyet WHO tarafndan 1996 ylnda deerlendirilmitir: 1990 ylnda dünya çapnda dorusal alkil benzen sülfonik asit tüketimi yaklak 2 milyon tondur. Sodyum dodesil benzen sülfonat eanlamls altnda dorusal dodesil benzen sülfonik asit, 1987 ylnda Amerika Birleik Devletleri Gda ve laç Dairesi’nin (FDA) gda katk maddesi listesine ykamada kullanlan ticari deterjanlarda yüzey aktif ajan olarak dahil edilmitir. meyve ve sebzeler veya bu ürünlerin sodal sularn soyulmasna yardmc olmak için. Tolerans snr ykama suyunda% 0,2’ye eit veya daha az olarak ayarlanmtr.

2. Molekülün hidrofobik ve hidrofilik gruplarnn her ikisi de, deterjanlardaki yüzey aktif maddelerin etkisi için gereklidir. Meme ucu daldrma uçlarnn in vitro antiseptik aktivitesi üzerine yaynlanan bir aratrmaya göre, dorusal alkil benzen sülfonik asit içeren ürünün (% 1,94), Escherichia coli, Staphylococcus aureus ve Streptococcus agalactiae süspansiyonlarna kar tamamen etkili olduu gösterilmitir. 2 dakikalk bir temas süresi.

n vitro çalmalarla ilgili yaynlanm bir inceleme belgesine göre, dorusal alkil benzen sülfonik asit için% 50 hemolitik konsantrasyon 9 mg / l ve protrombin süresi için% 50 inhibitör konsantrasyon 0.05 mmol / l (16.3 mg / l) idi. Dorusal alkil benzen sülfonik asit, protein-dorusal alkil benzen sülfonik asit etkileimini gösteren in vitro proteinlerin termal denatürasyonunu etkiledi.

3. Farmakokinetik veriler, yaynlanm raporlara dayanlarak sunulmutur. Sçanlarda, 14C-iaretli alkil benzen sülfonat, 5 hafta boyunca 12 erkek Wistar sçanna (120 ila 140 g) 1.4 mg / kg yem konsantrasyonunda (verilmez kg vücut arl bana doz) diyette günlük olarak uyguland. Radyoaktivite, 5 haftalk beslenme döneminde çounlukla dk (% 52) ve idrarla (% 29) atlmtr. 14C iaretli alkil benzen sülfonatn (384.7 ug / sçan) tek bir intraperitoneal uygulamasndan sonra, dozun% 85’i ilk 24 saat içinde ve% 95’i 10 günlük takip süresi içinde atlmtr. Ana eliminasyon yolu idrarla (radyoaktivitenin% 50’si),% 35’i feçesle atlr. Bununla birlikte, 2 ila 10. günlerde feçese atlan radyoaktivite yüzdesi, idrarla atlandan daha yüksekti. Dkda veya idrarda hiçbir ana bileik tespit edilememitir, ancak daha fazla karakterize edilmeyen polar metabolitlerde radyoaktivite bulunmutur. Baka bir çalmada, 35S etiketli lineer alkil benzen Sülfonik Asit, erkek albino sçanlara (Charles River suu, 150 ila 200 g vücut arl) 0.6, 1.2, 8 ve 40 mg / sçan (3 ila 5 sçanlar / grup). 3 günlük takip süresi boyunca, radyoaktivitenin% 40-58’i idrarla ve% 39-56’s feçesle atlmtr. Dkda, ana bileiin oran toplam radyoaktivitenin% 19’u idi. Dorusal alkil benzen Sülfonik Asidin yaklak% 70’i oral uygulamadan sonra emildi. Metil 4- (4′-metilsülfofenil) – pentanoata kimyasal olarak yakn iki idrar metaboliti belirlendi ve sülfofenil bütanoik asitler ve sülfofenil pentanoik asitlerin bir karm olduu bulundu. Sçanlarda dorusal alkil benzen Sülfonik Asit sülfonatn ayrmasnn, ϖ-oksidasyon ve ardndan bir β-oksidasyon mekanizmas yoluyla katabolizma ile meydana geldii ileri sürülmütür. In vitro çalmalar, 14C-iaretli dorusal alkil benzen sülfonik asidin, bozulmam sçan veya insan derisinden herhangi bir penetrasyonunu göstermemitir. Sçanlarda yaplan in vivo çalmalarda, 7.5 cm2 deri alanna 0.2 ml 3 mM 14C dorusal alkil benzen sülfonik asit (250 ug’ye edeer) uygulanmtr. Bu çalmalar, 14C etiketli dorusal alkil benzen sülfonik asidin cilt yüzeyinde ve saç köklerinin üst bölgelerinde biriktiini ortaya koydu, ancak 15 dakikalk bir maruziyetten sonra maddenin penetrasyonu tespit edilemedi.

4. Dorusal alkil benzen sülfonik asidin oral toksisitesi çok yüksek deildir. Sçanlar ve fareler için LD50 deerleri srasyla 404 ila 1525 mg / kg canl arlk ve 1575 ila 1950 mg / kg canl arlk aralndadr. Her iki tür de ishal gösterdi ve 24 saat içinde ölüm meydana geldi.

5. Tekrarlanan doz toksisitesi, dorusal alkil benzen sülfonik asitler veya bunlarn farkl uzunluklarda alkil zincirleri içeren sodyum tuzlar kullanlarak gerçekletirilmitir. Tekrarlanan doz toksisitesi, biri sçanlarda (60 dii ve 60 erkek / grup) sadece 1 doz seviyesi (0 ve 100 mg dorusal alkil benzen sülfonik asit (zincir uzunluu arasnda deien zincir uzunluu) kullanlarak yaplan 5 yaynlanm makale kullanlarak sçanlar üzerinde belgelenmitir. C10 ila C14) / l 100 hafta içme suyu). Test ve kontrol gruplar arasnda fark görülmedi. Çalma tasarmndaki eksiklikler nedeniyle NOEL kurulamamaktadr.

Wistar sçanlar (yaklak 150 g, cinsiyet ve grup bana 10) test ürününü ald (dorusal alkil benzen sülfonik asit içeren bulak ykama deterjan), 0, 0.015, 0.075 ve 0.375 ml dorusal alkil benzen sülfonik asit / kg’a karlk gelen içme suyuna kartrld 6 ay boyunca bw. 3.

grup doz 9 hafta sonra 0.563’e ve 8 hafta sonra tekrar 9 hafta 0.75 ml / kg canl arlk’a yükseltildi. Kontrol ve tedavi edilen hayvanlar arasnda hematolojik idrar incelemelerinde hiçbir farkllk görülmedi. Erkekler 3. doz grubunda kilo almnda azalma gösterdi, ancak tedavi durdurulduktan sonra deiiklik geri dönüümlü oldu. Tedaviden hemen sonra öldürülen üçüncü grup hayvanlarn (cinsiyet bana 5) organ arlklar, kontrollerinkinden daha düüktü. Sadece kontrol ve 3. tedavi gruplar histolojik olarak incelendi. 3. tedavi grubundaki hayvanlarda küçük peteiyal kanamalar (böbrek, miyokard, akcierler) ve gastrointestinal kanalda mukozal nekrotis lekeleri vard. Ayrca adrenal bezlerde büyük atrofi ve timusta bir miktar atrofi vard. Deiikliklerin doz ile korelasyon gösterip göstermediini deerlendirmek mümkün deildir, çünkü sadece en yüksek grup çallmtr. Mevcut snrl veriler nedeniyle çalmadan NOEL çkarlamaz. Albino sçanlar (FDRL suu, cinsiyet ve grup bana 15 hayvan), 12 hafta boyunca 0, 50 ve 250 mg / kg canl arlkta yemde dorusal alkil benzen sülfonik asit ald. Büyüme tepkileri ve besin alm, hematolojik ve idrar incelemeleri herhangi bir anormallik göstermedi. Histolojik bulgular, kontrol ile karlatrldnda daha düük doz grubunda herhangi bir anormallik göstermedi. Daha yüksek doz grubundaki kadnlarda, kontrollere göre daha yüksek karacier arl / vücut arl oran vard (p <0.01). 50 mg / kg canl arlk / gün’lük daha düük doz grubu, tedaviye bal herhangi bir deiiklik göstermedi. Mevcut snrl veriler nedeniyle NOEL oluturulamaz.

Sprague-Dawley sçan (cinsiyet ve grup bana 10 hayvan) 90 gün boyunca yemde lineer alkil benzen sülfonik asit (% 0, 0.02, 0.1 ve 0.5) ald (8.8, 44 ve 220 mg / kg canl arlk). Kilo art, besin kullanm, hematolojik ve idrar incelemelerinde istatistiksel olarak anlaml bir farkllk görülmedi. Organ-vücut oranlar ile makroskopik ve mikroskobik bulgular tedavi edilen ve kontrol gruplarnda karlatrlabilirdi. Mevcut snrl veriler nedeniyle NOEL oluturulamaz.

Charles River sçan (cinsiyet ve grup bana 50 hayvan), 2 yl boyunca yemde (0, 0.02, 0.1 ve 0.5%) dorusal alkil benzen sülfonik asit ald (kg canl arlk bana doz verilmemitir). lk 12 hafta boyunca kilo art ve gda kullanmnda istatistiksel olarak anlaml bir fark görülmedi. Organ-vücut oranlar, kontrol ve en yüksek doz gruplar karlatrldnda istatistiksel olarak anlaml bir farkllk göstermedi. Sekizinci ayda, 0.02 ve% 0.1 grubundaki erkek sçanlar daha düük karacier arl / vücut arl oranlarna sahipti, ancak bu daha sonraki zaman noktalarnda görülmedi ve hiçbir zaman en yüksek doz grubunda görülmedi. Hematolojik incelemeler tedavi ile ilgili herhangi bir deiiklik göstermedi. Anormal makroskopik bulgu görülmedi ve mikroskobik bulgular gruplar arasnda farkllk göstermedi. Mevcut snrl veriler nedeniyle NOEL oluturulamaz. En yüksek doz (2 yl boyunca yemde% 0,5) tedaviye bal herhangi bir deiiklik göstermemitir.

6 ila 7 aylk Beagle köpekleri (cinsiyet ve grup bana 2 hayvan) kullanlarak yaynlanm bir tekrarl doz toksisite çalmas yaplmtr. Dorusal alkil benzen sülfonik asit içeren bir ürün (% 15 dorusal alkil benzen sülfonik asit), gavaj yoluyla günlük 0, 10, 100 ve 1000 mg / kg canl arlk dozlarnda (0, 1.5, 15 ve 150 mg dorusal alkil benzen sülfonik asit / kg canl arlk). En düük doz grubu tedaviye bal deiiklik göstermedi. Orta doz seviyesi grubundaki bir dii köpek, ikinci haftadan itibaren salya akt ve bir hayvan, sedasyona ve itahn azalmasna yol açan bir dozun bir ksmn geri çekti. En yüksek doz grubunda 3 ila 4 hayvanda belirgin tükürük görüldü. Hayvan ölmedi. En yüksek doz grubunda yem alm orta derecede azalmtr. Kilo almnda belirgin azalma sadece en yüksek doz grubunda görülmütür (kadnlarda daha belirgindir). Kan ve idrar testlerinde deiiklik görülmedi. Tüm gruplarda gözler ve iitme normaldi. En yüksek doz grubunda mukozal erozyonlar bir erkek ve bir kadnda midede (esas olarak kardiada) bulundu. Dalakta hemosideroz varl en yüksek doz grubunda daha belirgindi. Ayn gruptaki bir köpein pankreasta küçük nekrozlar vard ve 2 köpein böbreklerinde bir miktar demir içermeyen pigment vard. Hayvan saysnn az olmas ve snrl veriler nedeniyle NOEL oluturulamaz. Bir WHO raporuna göre, farelere diyette lineer alkil benzen sülfonik asit veya 120 mg / dakikadan daha yüksek dozlara edeer konsantrasyonlarda içme suyunun uyguland subkronik çalmalarda karacierdeki biyokimyasal ve histopatolojik deiiklikler dahil minimal etkiler bildirilmitir. günlük vücut arl kg. Bu deiiklikler tersine çevrilebilir göründü. Orijinal verilerin yokluunda, DSÖ raporunda rapor edilen veriler hakknda kesin bir sonuca varlamaz.

6. Süt ineklerinde tolerans,% 2 dorusal alkil benzen sülfonik asit içeren ticari meme ucu daldrma kullanlarak incelenmitir. Ürün sam sonras 10 gün boyunca günde iki kez kullanld. Ürün iyi tolere edildi.

7. Üreme üzerindeki etkiler, biri sçanlarda (10 dii ve 10 erkek / grup) sadece bir doz seviyesinde lineer alkil benzen Sülfonik Asit sülfonik asit (0 ve 100 mg / l) kullanan bir çalmay tanmlayan 2 yaynlanm makale kullanlarak belgelenmitir. içme suyu). Salanan veriler deerlendirme için çok snrldr.

Charles River sçan (20 erkek ve 20 dii / grup), 3-nesil çalmada yemde lineer alkil benzen sülfonik asit (günlük% 0, 0.02, 0.1 ve 0.5) almtr (kg vücut arl bana doz verilmemitir). Yavrularda büyük bir anormallik kaydedilmedi. F1 ve F2 nesillerindeki sçanlar, kontrol ve test gruplarnda benzer büyüme modellerine ve organ-vücut arlk oranlarna sahipti. Histolojik incelemelerde herhangi bir anormallik görülmedi. Hematolojik çalmalarda, en yüksek test grubundaki kontrol ve kadnlar arasnda krmz kan hücresi saysnda istatistiksel olarak anlaml bir fark (anlamllk düzeyi belirtilmemitir) görülmütür. F3 sütten kesilmeleri büyüme, organ-vücut arlk oranlar, makroskopik ve mikroskobik incelemeler açsndan normaldi. Bu çalmada hematolojik deerler tedavi ile ilgili bir eilim veya model göstermedi. Salanan çalmalar herhangi bir üreme toksisitesi belirtisi göstermedi.

8. Teratojenite verileri, be makalede yaynlanan oral, dermal ve subkutan uygulama kullanlarak fare, sçan ve tavanda farkl dorusal alkil benzen Sülfonik Asit sülfonik asitler kullanlarak yürütülen çalmalardan elde edildi. ki fare çalmasnda, maruz kalma süreleri mevcut klavuzlara uygun deildir. Dermal veya subkutan uygulama kullanan farelerde yaplan bir çalma, mevcut klavuzlarda önerilenden farkl olarak daha küçük grup boyutlar ve maruz kalma süreleri kullanlarak gerçekletirildi. Dorusal alkil benzen sülfonik asit (günlük 0, 0.2, 2, 300 ve 600 mg / kg vücut arl), dii farelere (n = 20), sçanlara (n = 20) (gebeliin 6 ila 15. günleri) ve tavanlara ( n = 13) gebeliin 6 ila 18. günleri). Tüm türlerde, barajlardaki birincil toksik etkiler genellikle gastrointestinal sistemin bozulmas (ishal, itahszlk, yava kilo alm, kilo kayb, ölüm) ile ilikilendirilmitir. Tavanlar en duyarl türler olarak bulundu, ardndan fareler ve sçanlar geldi. En yüksek iki doz grubu, farelerde ve tavanlarda maternal toksisite gösterdi, bunun sonucunda fetal kayp artt ve yavru boyutu azald. Fare ve tavanlarda 2 mg / kg canl arlkta annelerde hiçbir etki görülmemitir. Sçanlarda, en yüksek doz ayrca maternal toksisiteye neden oldu, ancak çöp parametrelerini etkilemedi. Fetal arlklarda doza bal bir eilim görülmedi. Tedavi edilen gruplar ve kontroller arasnda majör malformasyonlarn saysnda hiçbir fark görülmedi. Farelerde, küçük iskelet anormallikleri 300 mg / kg canl arlk grubunda% 33.7’ye yükselirken, kontroller ve düük doz gruplarnda% 11.7 ila 13.3’e yükseldi. Farelerde 300 mg / kg canl arlk grubunda minör iskelet anomalilerindeki art dnda kontrollerden farkl teratolojik deiiklikler görülmedi. En yüksek doz grubundan, belirgin maternal toksisitenin bir sonucu olarak hiçbir canl genç bulunmamtr.

Fare, sçan ve tavanda dermal maruziyet (suda dorusal alkil benzen sülfonik asit) kullanldnda, en yüksek iki doz farelerde (50 ve 500 mg / kg canl arlk) ve tavanlarda (9 ve 90 mg / kg vücut arl) iddetli deri reaksiyonlarna neden olmutur. ). Sçanlarda en yüksek doz (60 mg / kg canl arlk) ayn zamanda cilt tahriini de göstermitir: 4 ila 5. günlerde en yüksek yantla birlikte eritem ve ödem Farelerdeki en yüksek doz grubu dnda, annelerde ve çöp verilerinde tedaviyle ilgili hiçbir etki görülmemitir. Farelerde, embriyonik ölümlerde önemli bir art (p <0.05), kontrollere kyasla 50 ve 500 mg / kg vücut arl düzeyinde görülmütür. Sçanlarda, tedavi edilen hayvanlarda çöp parametrelerinde önemli bir deiiklik görülmedi. Tavanlarda, en yüksek doz grubu biraz daha yüksek fetal kayp ve daha küçük yavru boyutuna sahipti (istatistiksel olarak anlaml deil). Anomalilerde istatistiksel olarak önemli bir farkllk görülmedi. Salanan çalmalar, maddenin herhangi bir teratojenik potansiyeline ilikin hiçbir gösterge göstermemitir. 9. Dorusal alkil benzen sülfonik asitler (C10 ila C14) kullanldnda (% 22,2 dorusal alkil benzen sülfonik asit çözeltisi, 10 ila 200 µl / plaka), Salmonella typhimurium TA100 ve TA98 testlerinin kullanld bir in vitro testte mutajenite kaydedilmedi. ve metabolik aktivasyon olmadan.

10. Resmi bir kanserojenlik çalmas yaplmamtr. Dorusal alkil benzen sülfonik asitlerin kullanld yaynlanm uzun vadeli toksisite çalmalar, malignitelerde art göstermemitir. Dorusal alkil benzen Sülfonik Asit sülfonik asitlerin kanserojen potansiyele sahip olduu kabul edilmez.

11. On Escherichia spp. (Escherichia coli) (ayrca aerobik MIC), Bifidobacterium spp, Bacteroides spp. (Bacteroides fragilis), Eubacterium spp, Clostridium spp, Streptococcus spp, Fusobacterium spp, Lactobacillis spp., Proteus spp. ve Peptostreptococcus spp. insan dksndan izole edilenler, agar-seyreltme deneyinde tüm türler için 128 µg / ml’den büyük MIC50 ve MIC90 deerlerine sahipti. nsan barsandaki bakteri türleri, dorusal alkil benzen sülfonik aside duyarl deildir.

12. Lactobacillus acidophilus, Lactobacillus rhamnosus ve Lactobacillus paracasei için sütte lineer alkil benzen sülfonik asit için MIC deerleri, Lactobacillus bulgaricus için 0,39 µg / ml ve test edilen dier Lactobacillus türleri ve Streptococcus thermophilus için 1,56 µg / ml idi.

0.0078 ug / ml. Çalma protokolü, incelenen konsantrasyon araln tanmlamaz. Bu nedenle, en düük MIC deerlerinin (0,0078 µg / ml) test edilen en düük konsantrasyona eit olup olmad net deildir. kinci çalmada dorusal alkil benzen sülfonik asidin süt kültürleri üzerindeki etkisi kültürlerdeki pH üzerindeki etkisi ölçülerek test edilmitir. Lactococcus lactis subsp. çin NOEL. lactis, 4 ug / ml idi. NOEL’ler, test edilen dier bakteri türleri için daha yüksekti (Lactococcus. Lactis subsp. Cremoris, Lactococcus lactis subsp. Lactis biovar diacetylactis, Leuconostoc mesenteroides subsp. Cremoris veya subsp. Dextranictobus subsp. bulgaricus, Lactobacillus Delbrueckii subsp. lactis ve Lactobacillus acidophilus). Süt kültürleri, sütte bulunan dorusal alkil benzen sülfonik asit konsantrasyonlarna duyarl deildi.

13. Yaynlanm bir gözden geçirme belgesine dayanarak, toplu testler, insan cildinin% 1’e kadar dorusal alkil benzen sülfonik asit içeren solüsyonlarla temas tolere edebileceini göstermektedir. Dorusal alkil benzen sülfonik asit tarafndan gönüllülere duyarllk indüklenmedi.

14. nsan ve çevresel maruziyet, 1996 ylnda DSÖ tarafndan deerlendirilmitir. Orijinal verilerin yokluunda, DSÖ raporunda rapor edilen veriler hakknda kesin bir sonuca varlamaz.

15. Mevcut snrl verilere dayanarak, genel olarak insanlarda lineer alkil benzen sülfonik asitlere günlük maruziyetin yaklak 5 mg / kii olduu tahmin edilmektedir; burada insan maruziyetinin birincil yolunun dermal temas yoluyla olduu ve daha az ölçüde olduu varsaylmaktadr içme suyu yoluyla yutulmas ve temizlik maddeleri ve kiisel bakm ürünlerinden kaynaklanan bulaklar ve yiyecekler üzerindeki kalntlarn bir sonucu olarak.

16. Bilgisizlik ve çalmalardaki yetersizlikler nedeniyle, NOEL’leri oluturmak ve dorusal alkil benzen sülfonik asit için bir ADI hesaplamak mümkün olmamtr. Ancak bunu göz önünde bulundurarak

• toksisite, mevcut tüm çalmalarda yalnzca yüksek doz seviyelerinde görülmütür

• mutajenite çalmalarnda pozitif bulgu rapor edilmemitir

• uzun süreli çalmalar kanserojen etkiler göstermedi,

CVMP, daha fazla toksisite çalmalarnn gerekli olmadn ve hayvansal kaynakl gda maddelerindeki dorusal alkil benzen sülfonik asit kalntlarnn insan tüketicisi için bir risk oluturmayacan deerlendirdi.

17. Emilim, 10 gün boyunca% 2 lineer alkil benzen sülfonik asit içeren ticari meme ucu daldrma ile sam sonras ilem gören 8 inein üzerinde çallmtr. Plazma örnekleri tedavi srasnda samdan hemen önce 2, 4, 6, 8 ve 10. günlerde günde bir kez ve ilemin bitiminden sonra 2, 3, 4 ve 5. günlerde alnmtr.

tedavi. Dorusal alkil benzen sülfonik asit konsantrasyonlar, 35 ug / l’lik bir saptama limiti ve 50 ug / l’lik bir miktar belirleme limiti ile dorulanm bir HPLC / floresan yöntemi ile ölçüldü. Yöntemin 50 ila 500 µg / l konsantrasyon aralnda plazmada dorusal olduu gösterilmitir. Dorusal alkil benzen sülfonik asitler, iki numune (125 µg / l ve 53 µg / l) dnda plazma örneklerinde tespit edilmemitir. Dorusal alkil benzen sülfonik asitlerin, sonradan daldrma için kullanldklarnda deriden kan dolamna büyük ölçüde emilmedii sonucuna varlmtr.

18. Sam sonras% 2 lineer alkil benzen sülfonik asit içeren ticari meme ucu daldrma ilemine tabi tutulan 8 inein sütünde 10 gün süreyle meme daldrma ile kalntlar belirlendi. Muamele srasnda 2, 4, 6, 8 ve 10. günlerde ve ilemin bitiminden sonra 2, 3, 4 ve 5. günlerde analiz için samdan önce süt örnekleri alnd. Dorusal alkil benzen sülfonik asit konsantrasyonlar, 30 ug / l’lik bir saptama limiti ve 100 ug / l’lik bir miktar belirleme limiti ile dorulanm bir HPLC / floresan yöntemi ile ölçüldü. Yöntemin 100 ila 4000 µg / l konsantrasyon aralnda sütte dorusal olduu gösterilmitir. lem srasnda, kalntlar 30 ug / l ila 208 ug / l aralndayd. Numunelerin çounda konsantrasyon, tespit limitinin veya miktar tayini limitinin altndayd. Muamelenin sona ermesinden sonra, sütteki kalnt konsantrasyonlar, muamelenin bitiminden 2. günde bir inein bir salmas dnda, 344 ug / l’lik bir konsantrasyon gösteren, harici kontaminasyonun neden olabilecei miktar tayini snrnn altnda kalmtr.

Sonuç ve öneri

2377/90 Sayl Konsey Tüzüü (EEC) Ek II’deki maddelerin dahil edilmesi için Veteriner Tbbi Ürünler Komitesi tarafndan konulan kriterleri ve özellikle aadakileri dikkate alarak:

• toksisite sadece mevcut tüm çalmalarda yüksek doz seviyelerinde görülmütür,

• teratojenik etki bildirilmemitir,

• mutajenite çalmalarnda herhangi bir pozitif bulgu rapor edilmemitir,

• uzun süreli çalmalar kanserojen etkiler göstermedi,

• in vitro 128 µg / ml doza kadar insan barsa bakterilerine duyarllk yoktu,

• 4 µg / ml’ye kadar konsantrasyonlarda ilgili süt kültürleri üzerinde herhangi bir etki yoktu,

• Dorusal alkil benzen sülfonik asitlerin memeye uygulandktan sonra sistemik biyoyararlanm ihmal edilebilir görünmektedir,

• sütte gözlemlenen maksimum kalnt konsantrasyonlar bile toksikolojik veya mikrobiyolojik etkilerin beklenebilecei herhangi bir doz seviyesinin veya konsantrasyonun çok altndayd; Veteriner Tbbi Ürünler Komitesi, dorusal alkil benzen sülfonik asitler için bir MRL oluturulmasna gerek olmad sonucuna varr ve aadaki tabloya uygun olarak 2377/90 sayl Konsey Tüzüü (EEC) Ek II’ye dahil edilmesini tavsiye eder: Farmakolojik olarak aktif madde ( s)

Abeson, üstün temizleme gücüne ve çok çeitli dier anyonik, noniyonik ve amfoterik yüzey aktif maddelerle uyumlulua sahip anyonik bir yüzey aktif maddedir. Asidik ortamlarda deterjan olarak ayr kullanma uygun, yüksek verimli çok yönlü yüzey aktif maddedir.

Ara ürün olarak, çok sayda endüstride, en yaygn olarak sv ve toz deterjanlar, ev ve I&I temizleyicileri, çamar deterjanlar, bulak ykama svlar, araba ykama ürünleri, sert yüzey temizleyicileri vb. Üretiminde kullanlan sülfonatlar üretmek için genellikle çeitli bazlarla nötrletirilir. Bunlarn yan sra Abeson, tarm, emülsiyon polimerizasyonu, petrol sahas kimyasallar gibi çeitli endüstriyel uygulamalarda uygulanmaktadr.

Açklama

Eanlamllar LAS; Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit); LABS; Laurilbenzensülfonik Asit; Laurilbenzensülfonat; Dorusal Alkil benzen Sülfonik Asit; DDBSA; Dodesil Benzen Sülfonik Asit; Dodesil Benzen Sülfonik Asit

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) olarak da bilinen dorusal alkil benzen sülfonik asit, yaygn olarak kullanlan bir endüstriyel deterjan olan sentetik bir kimyasal yüzey aktif maddedir. Çamar tozu, deterjan tozu, ya sabunu, temizlik tozu ve deterjan kekinde kullanlr.

AÇIKLAMA

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), molekülleri hidrofilik ve hidrofobik bir grupla karakterize edilen anyonik bir yüzey aktif maddedir. Bu uçucu olmayan kimyasal bileik, sülfonasyon ilemi yoluyla sentezlenir. Sülfonasyon reaktifleri arasnda sülfürik asit, klorosülfonik asit, sülfamik asit ve seyreltilmi sülfür trioksit bulunur.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’nn özellikleri, alkil zincirinin uzunluuna bal olarak kimyasal ve fiziksel özellikler bakmndan farkllk gösterir. Bu, birçok uygulama bulan formülasyonlarla sonuçlanr. Elde edilen yüzey aktif maddeler kimya endüstrisinde su ve mineraller arasndaki temas iyiletirmek için kullanlr.

KULLANIMI

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) esas olarak deterjan endüstrisinde çamar tozu, deterjan tozu, deterjan keki, sv sabun, ya sabunu, ovma çubuu ve temizleme tozu üretiminde kullanlmaktadr. Bu kimyasal, anyonik özel formülasyonlarda uygulama bulur. Böcek ilac spreylerinin kalitesi ondan iyiletirilebilir.

Dorusal alkil benzen sülfonik asit, tekstil endüstrisinde ykama ve merserize etme ajan olarak kullanlr. Hastaln yüzey alan Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) kullanlarak artrlr. Tuvalet sabunlarnn köpürtülmesi için dier yüzey aktif maddelerle birlikte bir slatma maddesi ve ayn zamanda bir emülgatör olarak küçük miktarlarda kullanlr.

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), yüksek etken madde içerii ve düük tuz içerii ve su ile karabilirlii sayesinde emülsiyonlarn polimerizasyonunda ve balama maddeleri, emülgatörler, zirai herbisitler, evsel ve endüstriyel temizleyiciler üretiminde kullanlr.

ÇEVRE VE GÜVENLK HUSUSLARI

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) dahil çou anyonik yüzey aktif madde, doas gerei toksik deildir. Bununla birlikte, bu yüzey aktif maddelere uzun süre maruz kalmak, cildi ve dier hücreleri koruyan lipid membrann bozulmas yoluyla cildi tahri edebilir ve zarar verebilir. Öte yandan, biyolojik olarak parçalanabilirlik, yüzey aktif maddenin hidrofobik hidrokarbon grubu tarafndan belirlenir.

AVANTAJLARI

Dorusal Alkil Benzen Sülfonik Asit, düük maliyeti ve yüksek performans nedeniyle hacimce en büyük sentetik yüzey aktif maddelerden biridir. Bunun dnda Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit), stabil bir toz formuna kurutulabilir. Bu kimyasal biyolojik olarak parçalanabilir ve çevre dostudur.

ndirimli bir fiyata fazla Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit) stoku satn aln.Ürün Açklamas

Dorusal Alkil Benzen Sülfonik Asit

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 90, nispeten düük maliyeti, iyi performans, kararl bir toz halinde kurutulabilmesi ve biyolojik olarak parçalanabilir çevre dostu olmas nedeniyle en büyük hacimli sentetik yüzey aktif maddedir. LAB Sülfonik Asit, tüm Ev Tipi Deterjan Toz, Kek ve Bulak ykama temizleyicilerinin formülasyonunda yaygn olarak kullanlan bir anyonik yüzey aktif maddedir. Yüksek aktif maddesi, su ile karabilirlii ve düük tuz içerii nedeniyle, Endüstriyel ve Ev tipi sv temizleyicilerin formülasyonunda ve ayrca bir balama maddesi olarak ve tarmsal herbisitler için emülgatör olarak ve emülsiyon polimerizasyonunda çok sayda endüstriyel uygulamada kullanlr. .

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 90 – Yumuak Asit Bulamac, aadakiler için ana hammaddedir:

Deterjan tozu, Deterjan tozu, Deterjan keki, Sv Sabun, Temizleme tozu, Ovma çubuu, Ya sabunlar vb. Formülasyonlarnda sentetik deterjan endüstrileri.

Anyonik özel formülasyonlarda kullanlr.

Tekstil endüstrisi gibi dier endüstrilerde merserize veya ykama maddesi olarak kullanlr.

Gençlerin yüzey alann artrmak için kullanlr.

Pasta, Toz ve Sv formülasyonlar gibi tüm Deterjanlarda ana etken madde olarak

Dier yüzey aktif maddelerle birlikte az miktarda emülgatör ve slatma ajan olarak köpüklü tuvalet sabunlarnda

Pestisitlerde sprey kalitesini artrmak için

Maliyet Faktörü

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 90 Sülfonasyon Tesisi Maliyeti, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 96 Sülfonasyon tesisine göre 1/10 orannda olup, Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 90’n tüketicilere Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)’ya kyasla rekabetçi fiyatlarla sunulmas sonucunda büyük maliyet avantaj salar. % 96

Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 90, tüm Deterjan Tozlar için ortak bileen olan Soda Külü ile reaksiyona girdiinde Glauber Tuzuna (Sodyum Sülfat) dönüen% 5-6 Serbest Asit içerir. Bu Glauber Tuzu, Son Ürün, yani Deterjan Tozunun serbestçe akmasna yardmc olur ve Kalsiyum LABSA (calcium LABSA, kalsiyum dorusal alkil benzen sülfonik asit)% 96 ile formüle edilen Deterjanlarda bulunmayan topaklanma önleyici özellikler verir.

CALCIUM LABSA (KALSYUM LABSA)

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