CAPRYLIC ACID (KAPRLK AST)
CAPRYLIC ACID (KAPRLK AST)
CAS No. : 124-07-2
EC No. : 204-677-5
Synonyms:
octanoic acid; caprylic acid; 124-07-2; n-octanoic acid; Octylic acid; n-caprylic acid; octoic acid; n-octylic acid; n-Octoic acid; neo-fat 8; 1-heptanecarboxylic acid; Enantic acid; Octic acid; C-8 acid; Caprylsaeure; Kaprylsaeure; Hexacid 898; Acido octanoico; 0ctanoic acid; Acide octanoique; 1-octanoic acid; Acidum octanocium; Fatty acids, C6-10; FEMA No. 2799; Kyselina kaprylova; capryloate; C8:0; octylate; Octansaeure; Caprylic acid (natural); Acide octanoique [French]; Acido octanoico [Spanish]; Acidum octanocium [Latin]; Kyselina kaprylova [Czech]; NSC 5024; Octanoic acid [USAN:INN]; UNII-OBL58JN025; OCTANOIC ACID (CAPRYLIC ACID); CCRIS 4689; HSDB 821; CHEBI:28837; Emery 657; Prifac 2901; Lunac 8-95; NSC-5024; Carboxylic acids, C5-9; EINECS 204-677-5; MFCD00004429; BRN 1747180; CH3-[CH2]6-COOH; AI3-04162; caprylic acid, zinc salt; OBL58JN025; caprylic acid, barium salt; caprylic acid, sodium salt; NSC5024; caprylic acid, cadmium salt; caprilate; EDENOR C 8-98-100; Caprylic acid, potassium salt; n-caprylate; caprylic acid, tin(+2) salt; n-octoate; n-octylate; caprylic acid, copper(+2) salt; Octanoic acid, 99%; NCGC00090957-01; C8H16O2; 1-heptanecarboxylate; DSSTox_CID_1645; DSSTox_RID_76259; DSSTox_GSID_21645; OCA; CAS-124-07-2; CH3-[CH2]6-COO(-); caprylic acid, tin salt; caprylic acid, cesium salt; caprylic acid, cobalt salt; caprylic acid, copper salt; caprylic acid, ammonia salt; caprylic acid, calcium salt; caprylic acid, 14C-labeled; octanoicacid; caprylic acid, aluminum salt; caprylic acid, manganese salt; caprylic acid, zirconium salt; octanic acid; Caprilic acid; caprylic acid, iron(+3) salt; caprylic acid, lead(+2) salt; acidum octanoicum; octanoate radical; caprylic acid, iridum(+3) salt; caprylic acid, nickel(+2) salt; caprylic acid, chromium(+2) salt; caprylic acid, lanthanum(+3) salt; caprylic acid, ruthenium(+3) salt; caprylic acid, zirconium(+4) salt; EINECS 273-085-7; Acid C8; Octanoic acid radical ; Caprylic acid (NF); Kortacid 0899; Neo-Fat 8S; Caprylic Acid 657; Octanoate, ion(1-); caprylic acid, sodium salt, 11C-labeled; n-heptanecarboxylic acid; Octanoic acid (USAN); Fatty acids, C6-1O; ACMC-1BTHQ; Lunac 8-98; 7319-86-0; Heptane-1-carboxylic acid; Octanoic acid, >=98%; Octanoic acid, >=99%; bmse000502; Caprylic/Capric Acid Blend; CCCCCCCC([O])=O; EC 204-677-5; SCHEMBL3933; WLN: QV7; NCIOpen2_002902; NCIOpen2_009358; Octanoic acid (USAN/INN); Caprylic acid/ Octanoic acid; 4-02-00-00982 (Beilstein Handbook Reference); 68937-74-6; KSC174S6D; MLS002415762; Octanoic acid, >=96.0%; Octanoic acid (mixed isomers); CHEMBL324846; GTPL4585; Octanoic acid, >=98%, FG; QSPL 011; QSPL 184; DTXSID3021645; CTK0H4961; KS-00000WZB; HMS2270A23; Octanoic acid, analytical standard; STR10050; ZINC1530416; Tox21_111045; Tox21_201279; Tox21_300345; ANW-18188; BDBM50485608; LMFA01010008; LS-691; s6296; SBB060020; STL282742; AKOS000118802; Octanoic acid, natural, >=98%, FG; DB04519; FA(8:0); MCULE-5193957469; NE10316; Octanoic acid, for synthesis, 99.5%; NCGC00090957-02; NCGC00090957-03; NCGC00090957-04; NCGC00090957-05; NCGC00254446-01; NCGC00258831-01; HY-41417; M789; SMR001252279; 597-EP2269988A2; 597-EP2270008A1; 597-EP2275413A1; 597-EP2287156A1; 597-EP2292617A1; 597-EP2298780A1; 597-EP2301940A1; 597-EP2305689A1; 597-EP2311807A1; 597-EP2311824A1; 597-EP2374787A1; AK00487762; CS-0016549; FT-0660765; O0027; ST51046283; C06423; D05220; 146488-EP2280007A1; 146488-EP2292597A1; Q409564; SR-01000865607; J-005040; SR-01000865607-2; BRD-K35170555-001-07-9; Z955123584; Octanoic acid, certified reference material, TraceCERT(R); UNII-13FB83DEYU component WWZKQHOCKIZLMA-UHFFFAOYSA-N; UNII-DI775RT244 component WWZKQHOCKIZLMA-UHFFFAOYSA-N; 43FDA9D7-2300-41E7-A373-A34F25B81553; Caprylic acid, European Pharmacopoeia (EP) Reference Standard; UNII-79P21R4317 component WWZKQHOCKIZLMA-UHFFFAOYSA-N; Caprylic acid, United States Pharmacopeia (USP) Reference Standard; Caprylic Acid (Octanoic Acid), Pharmaceutical Secondary Standard; Certified Reference Material
EN
Caprylic Acid IUPAC Name octanoic acid
Caprylic Acid InChI InChI=1S/C8H16O2/c1-2-3-4-5-6-7-8(9)10/h2-7H2,1H3,(H,9,10)
Caprylic Acid InChI Key WWZKQHOCKIZLMA-UHFFFAOYSA-N
Caprylic Acid Canonical SMILES CCCCCCCC(=O)O
Caprylic Acid Molecular Formula C8H16O2
Caprylic Acid CAS 124-07-2
Caprylic Acid Related CAS 15696-43-2
Caprylic Acid Deprecated CAS 2171005-29-9
Caprylic Acid European Community (EC) Number 204-677-5
Caprylic Acid NSC Number 5024
Caprylic Acid UN Number 3265
Caprylic Acid UNII OBL58JN025
Caprylic Acid JECFA Number 99
Caprylic Acid FEMA Number 2799
Caprylic Acid DSSTox Substance ID DTXSID3021645
Caprylic Acid Physical Description Liquid
Caprylic Acid Color/Form Colorless
Caprylic Acid Odor FAINT, FRUITY-ACID ODOR
Caprylic Acid Taste Slightly sour taste
Caprylic Acid Boiling Point 463.5 °F at 760 mm Hg
Caprylic Acid Melting Point 61 to 62 °F
Caprylic Acid Flash Point 230 °F
Caprylic Acid Solubility less than 1 mg/mL at 64° F
Caprylic Acid Density 0.91
Caprylic Acid Vapor Pressure 1 mm Hg at 198.1 °F ; 5 mm Hg at 237.4° F; 760 mm Hg at 459.5° F
Caprylic Acid LogP 3.05
Caprylic Acid Decomposition When heated to decomposition it emits acrid smoke and irritating fumes.
Caprylic Acid Viscosity 5.74 mPa.sec
Caprylic Acid Heat of Combustion -4,799.9 kJ/mol
Caprylic Acid Surface Tension 23.7 dyn/cm
Caprylic Acid Odor Threshold IT CAN BE DETECTED @ 0.008 PPM.
Caprylic Acid pKa 4.89 (at 25 °C)
Caprylic Acid Molecular Weight 144.21 g/mol
Caprylic Acid XLogP3 3
Caprylic Acid Hydrogen Bond Donor Count 1
Caprylic Acid Hydrogen Bond Acceptor Count 2
Caprylic Acid Rotatable Bond Count 6
Caprylic Acid Exact Mass 144.11503 g/mol
Caprylic Acid Monoisotopic Mass 144.11503 g/mol
Caprylic Acid Topological Polar Surface Area 37.3 Ų
Caprylic Acid Heavy Atom Count 10
Caprylic Acid Formal Charge 0
Caprylic Acid Complexity 89.3
Caprylic Acid Isotope Atom Count 0
Caprylic Acid Defined Atom Stereocenter Count 0
Caprylic Acid Undefined Atom Stereocenter Count 0
Caprylic Acid Defined Bond Stereocenter Count 0
Caprylic Acid Undefined Bond Stereocenter Count 0
Caprylic Acid Covalently-Bonded Unit Count 1
Caprylic Acid Compound Is Canonicalized Yes
Caprylic Acid Health Benefits
Caprylic Acid, taken either by mouth or used topically, is thought to treat a number of health conditions, including:
Acne
Alzheimer’s disease
Bacterial skin infections
Candidiasis (including yeast infections and oral thrush)
Epilepsy
Hyperlipidemia (high cholesterol and triglycerides)
Hypertension (high blood pressure)
Inflammatory bowel diseases (IBD)
Lactose intolerance
Obesity
Tinea corporis (ringworm)
Caprylic Acid is a saturated medium-chain fatty acid with an 8-carbon backbone. Caprylic Acid is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil.Caprylic Acid appears as a colorless to light yellow liquid with a mild odor. Burns, but may be difficult to ignite. Corrosive to metals and tissue.Caprylic Acid is a straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Caprylic Acid is also known as Caprylic Acid. It has a role as an antibacterial agent, a human metabolite and an Escherichia coli metabolite. It is a straight-chain saturated fatty acid and a medium-chain fatty acid. It is a conjugate acid of an octanoate.Caprylic Acid (from the Latin word capra, meaning “goat”), also known under the systematic name octanoic acid, is a saturated fatty acid and carboxylic acid with the structural formula CH3(CH2)6CO2H. It is a colorless oily liquid that is minimally soluble in water with a slightly unpleasant rancid-like smell and taste.[1] Salts and esters of octanoic acid are known as octanoates or caprylates. It is a common industrial chemical, which is produced by oxidation of the C8 aldehyde.[4] Its compounds are found naturally in the milk of various mammals and as a minor constituent of coconut oil and palm kernel oil.Caprylic Acid is used commercially in the production of esters used in perfumery and also in the manufacture of dyes.Caprylic Acid is an antimicrobial pesticide used as a food contact surface sanitizer in commercial food handling establishments on dairy equipment, food processing equipment, breweries, wineries, and beverage processing plants. It is also used as disinfectant in health care facilities, schools/colleges, animal care/veterinary facilities, industrial facilities, office buildings, recreational facilities, retail and wholesale establishments, livestock premises, restaurants, and hotels/motels. In addition, Caprylic Acid is used as an algicide, bactericide, fungicide, and herbicide in nurseries, greenhouses, garden centers, and interiors, and on ornamentation. Products containing Caprylic Acid are formulated as soluble concentrate/liquids and ready-to-use liquids.[5]Caprylic Acid plays an important role in the body’s regulation of energy input and output, a function which is performed by the hormone ghrelin. The sensation of hunger is a signal that the body requires an input of energy in the form of food consumption. Ghrelin stimulates hunger by triggering receptors in the hypothalamus. In order to activate these receptors, ghrelin must undergo a process called acylation in which it acquires an -OH group, and Caprylic Acid provides this by linking at a specific site on ghrelin molecules. Other fatty acids in the same position have similar effects on hunger.Caprylic Acid is currently being researched as a treatment for essential tremor.[6][7]The acid chloride of Caprylic Acid is used in the synthesis of perfluorooctanoic acid.Caprylic Acid is taken as a dietary supplement. In the body, Caprylic Acid would be found as octanoate, or unprotonated Caprylic Acid.[8]Some studies have shown that medium-chain triglycerides (MCTs) can help in the process of excess calorie burning, and thus weight loss;[9][10][11][12][13] however, a systematic review of the evidence concluded that the overall results are inconclusive.[14] Also, interest in MCTs has been shown by endurance athletes and the bodybuilding community, but MCTs have not been found to be beneficial to improved exercise performance.[13]Caprylic Acid has been studied as part of a ketogenic diet to treat children with intractable epilepsy.Caprylic Acid, also called octanoic acid, is an oily liquid found in the milk of certain mammals as well as coconut oil and palm oil. It is a medium-chain saturated fatty acid widely used in the manufacture of dyes, perfumes, sanitizers, and disinfections.Caprylic Acid can also be formulated into dietary supplements, where it is said to have antimicrobial and anti-inflammatory properties. It is a popular ingredient in many anti-aging creams and is the main component of medium-chain triglyceride (MCT) oil, a dietary supplement believed to aid in weight loss and athletic performance.Caprylic Acid is also sometimes used to prevent hypoalbuminemia (low albumin) in people undergoing dialysis. Caused in part by the low-protein diet people with severe kidney disease need to maintain, hypoalbuminemia is a predictor of poor outcomes for people on dialysis.Caprylic Acid supplements are commonly sold as an over-the-counter supplement for oral and vaginal candidiasis. Candidiasis is the medical term used to describe oral thrush and vaginal yeast infections, the conditions of which are associated with the Candida albicans fungi.A 2017 study in the Journal of Medicinal Food concluded that Caprylic Acid was able to inhibit the growth of C. albicans in test-tube studies by arresting cell development at three different stages in its life cycle.Popularly included in weight-loss products, Caprylic Acid is believed to work by suppressing hunger. In the human body, the “hunger hormone” ghrelin is activated whenever the stomach is empty. There is both acylated ghrelin, which contributes to hunger, and unacylated ghrelin, which is believed to improve glycemic control and suppress hunger.It had long been assumed that Caprylic Acid enhances the production of unacylated ghrelin, thereby suppressing hunger and maintaining satiety (a feeling of fullness). But, a 2015 study in PLoS One reported a contradictory effect.According to the researchers, lab rats fed a diet high in Caprylic Acid had no increase in their acylated ghrelin but instead had a significant decrease in unacylated ghrelin. Findings like these suggest that Caprylic Acid is unlikely to aid with weight loss.There is growing evidence that Caprylic Acid may help reduce the number of seizures in people with epilepsy. According to a 2013 study published in Case Reports in Neurological Medicine, doctors with Vanderbilt University Medical Center reported that a 43-year-old man with treatment-resistant epilepsy experienced a steep reduction in seizures after being prescribed a twice-daily, four-tablespoon dose of MCT oil.There is some evidence that caprylic can slow the progression of mild to moderate Alzheimer’s disease. A 2013 review of studies in Neuropsychiatric Disease and Treatment reported that adults with Alzheimer’s given a daily 20-gram dose of Caprylic Acid experienced a slower decline in cognitive function than those who weren’t. The results were monitored using the Mini-Mental State Examination (MMSE) test.Caprylic Acid is also the active ingredient of a supplement called Axona, which the manufacturers claim can aid in the treatment of Alzheimer’s disease. Despite undergoing Phase I and Phase II clinical trials (in which Axona showed some benefit), the manufacturers decided to skip Phase III studies and market Axona as a “medical food” for people with Alzheimer’s.Further research is needed to provide stronger evidence of Caprylic Acid’s benefits in treating Alzheimer’s disease.Caprylic Acid may aid in the control of inflammatory bowel diseases (IBD), including Crohn’s disease and the typically more severe ulcerative colitis.According to a 2019 study in Inflammatory Bowel Disease, a daily 2-gram dose of Caprylic Acid prevented the relapse of symptoms in adults with ulcerative colitis. Endoscopic and tissue biopsy evaluations confirmed a reduction in inflammation and ulcerative damage to the lining of the intestinal tract compared to pretreatment values.Although the effectiveness of Caprylic Acid has varied between studies, medium-chain fatty acids are believed to suppress the production of interleukin-8 (IL-8), an inflammatory cytokine found in excessive quantities in people with IBD.Caprylic Acid supplements are generally considered safe if used as prescribed. Common side effects include nausea, flatulence, constipation, heartburn, indigestion, and diarrhea. High doses may trigger an abnormal drop in calcium levels (hypocalcemia), causing growth problems in children and an increased risk of brittle bones in people with osteoporosis.Caprylic Acid may not be appropriate for people with liver disease or hypotension (low blood pressure) as an increased fatty acid intake is known to complicate both conditions.Caprylic Acids should be avoided in people with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency who are unable to break down fatty acids efficiently. The excessive build-up of Caprylic Acid can trigger hypoglycemia (low blood sugar), vomiting, and, in severe cases, coma.The safety of Caprylic Acid in children, pregnant women, and nursing mothers has not been established. For safety sake, it is best to avoid Caprylic Acid unless under the supervision of qualified pediatrician or OB/GYN.It is not known if Caprylic Acid supplements can interact with other medications.Widely available for purchase online, Caprylic Acid supplements can also be found in drugstores, natural food shops, and stores specializing in dietary supplements.When formulated as capsules, Caprylic Acid is typically sold as “fungal defense” supplement against yeast infections and thrush. The majority of these products are sold in multi-ingredient supplements rather than as a dedicated Caprylic Acid supplement.There are no guidelines for the appropriate use of Caprylic Acid or MCT oil. Studies exploring the benefits of Caprylic Acid in people with Alzheimer’s have used up to 20 grams (20,000 milligrams) per day, although intake of this level could potentially be harmful. Most co-formulated supplements contain 500 milligrams of Caprylic Acid, a far safer amount.
TR
Kaprilik Asit IUPAC Ad octanoic acid
Kaprilik Asit InChI InChI = 1S / C8H16O2 / c1-2-3-4-5-6-7-8 (9) 10 / h2-7H2,1H3, (H, 9,10)
Kaprilik Asit InChI Key WWZKQHOCKIZLMA-UHFFFAOYSA-N
Kaprilik Asit Kanonik SMILES CCCCCCCC (= O) O
Kaprilik Asit Moleküler Formül C8H16O2
Kaprilik Asit CAS 124-07-2
Kaprilik Asit lgili CAS 15696-43-2
Kaprilik Asit Kullanmdan Kaldrlm CAS 2171005-29-9
Kaprilik Asit Avrupa Topluluu (EC) Numara 204-677-5
Kaprilik Asit NSC Numaras 5024
Kaprilik Asit UN Numaras 3265
Kaprilik Asit UNII OBL58JN025
Kaprilik Asit JECFA Numaras 99
Kaprilik Asit FEMA Numaras 2799
Kaprilik Asit DSSTox Substance ID DTXSID3021645
Kaprilik Asit Fiziksel Tanm Sv
Kaprilik Asit Renk / Form Renksiz
Kaprilik Asit Koku FAINT, MEYVE-AST KOKUSU
Kaprilik Asit Tat Hafif eki tat
Kaprilik Asit Kaynama Noktas 463.5 ° F, 760 mm Hg’de
Kaprilik Asit Erime Noktas 61 ila 62 ° F
Kaprilik Asit Parlama Noktas 230 ° F
Kaprilik Asit 64 ° F’de 1 mg / mL’den az çözünürlük
Kaprilik Asit Younluk 0.91
Kaprilik Asit Buhar Basnc 198.1 ° F’de 1 mm Hg; 237.4 ° F’de 5 mm Hg; 459,5 ° F’de 760 mm Hg
Kaprilik Asit LogP 3.05
Kaprilik Asit Ayrma Ayrma için stldnda keskin duman ve tahri edici dumanlar yayar.
Kaprilik Asit Viskozite 5,74 mPa.sn
Kaprilik Asit Yanma Iss -4.799.9 kJ / mol
Kaprilik Asit Yüzey Gerilimi 23.7 dyn / cm
Kaprilik Asit Koku Eii 0,008 PPM’de TESPT EDLEBLR.
Kaprilik Asit pKa 4.89 (25 ° C’de)
Kaprilik Asit Moleküler Arlk 144,21 g / mol
Kaprilik Asit XLogP3 3
Kaprilik Asit Hidrojen Ba Donör Says 1
Kaprilik Asit Hydrogen Bond Acceptor Count 2
Kaprilik Asit Rotatable Bond Count 6
Kaprilik Asit Tam Kütle 144.11503 g / mol
Kaprilik Asit Monoizotopik Kütle 144.11503 g / mol
Kaprilik Asit Topolojik Polar Yüzey Alan 37.3 Ų
Kaprilik Asit Heavy Atom Count 10
Kaprilik Asit Resmi Ücret 0
Kaprilik Asit Karmakl 89.3
Kaprilik Asit zotop Atom Saym 0
Kaprilik Asit Tanml Atom Stereocenter Says 0
Kaprilik Asit Tanmsz Atom Stereocenter Says 0
Kaprilik Asit Tanml Ba Stereocenter Says 0
Kaprilik Asit Tanmsz Ba Stereocenter Says 0
Kaprilik Asit Kovalent Bal Birim Says 1
Kaprilik Asit Bileii Kanonikletirilmitir Evet
Kaprilik Asit Salk Faydalar
Az yoluyla alnan veya topikal olarak kullanlan Kaprilik Asit’in (Kaprilik Asit), aadakiler dahil bir dizi salk koulunu tedavi ettii düünülmektedir:
Akne
Alzheimer hastal
Bakteriyel cilt enfeksiyonlar
Kandidiyaz (maya enfeksiyonlar ve oral pamukçuk dahil)
Epilepsi
Hiperlipidemi (yüksek kolesterol ve trigliseritler)
Hipertansiyon (yüksek tansiyon)
nflamatuar barsak hastalklar (IBD)
Laktoz intolerans
Obezite
Tinea corporis (saçkran)
Kaprilik Asit, 8 karbonlu omurgaya sahip doymu bir orta zincirli ya asididir. Kaprilik Asit, çeitli memelilerin sütünde doal olarak bulunur ve hindistancevizi ya ve hurma çekirdei yann küçük bir bileenidir Kaprilik Asit, hafif bir kokuya sahip renksiz ila açk sar bir sv olarak görünür. Yanar, ancak tutumas zor olabilir. Metaller ve dokular için andrcdr. Kaprilik Asit, içinde bir terminal metil grubunun hidrojenlerinden birinin bir karboksi grubu ile deitirildii heptan olan düz zincirli doymu bir ya asididir. Kaprilik Asit, Kaprilik Asit olarak da bilinir. Bir antibakteriyel ajan, bir insan metaboliti ve bir Escherichia coli metaboliti olarak rol oynar. Düz zincirli doymu bir ya asidi ve orta zincirli bir ya asididir. Bir oktanoatn elenik asididir. Kaprilik Asit (Latince capra kelimesinden, “keçi” anlamna gelir), ayn zamanda sistematik ad altnda da bilinen oktanoik asit, CH3 yapsal formülüne sahip bir doymu ya asidi ve karboksilik asittir. (CH2) 6C02H. Hafif naho, ekimsi bir koku ve tada sahip, suda en az çözünür olan renksiz yal bir svdr. [1] Oktanoik asit tuzlar ve esterleri, oktanoatlar veya kaprilatlar olarak bilinir. C8 aldehitin oksidasyonu ile üretilen yaygn bir endüstriyel kimyasaldr. [4] Bileikleri, çeitli memelilerin sütünde doal olarak ve hindistancevizi ya ve hurma çekirdei yann küçük bir bileeni olarak bulunur. Kaprilik Asit kullanlr.ticari olarak parfümeride kullanlan esterlerin üretiminde ve ayrca boyalarn üretiminde Kaprilik Asit, süt ürünleri, gda ileme ekipmanlar, bira fabrikalar, arap imalathaneleri üzerindeki ticari gda ileme kurulularnda gda ile temas eden yüzey dezenfektan olarak kullanlan antimikrobiyal bir pestisittir. ve içecek ileme tesisleri. Salk tesislerinde, okullarda / kolejlerde, hayvan bakm / veterinerlik tesislerinde, endüstriyel tesislerde, ofis binalarnda, dinlenme tesislerinde, perakende ve toptan sat iletmelerinde, hayvanclk tesislerinde, restoranlarda ve otel / motellerde dezenfektan olarak kullanlmaktadr. Ek olarak, Kaprilik Asit fidanlklarda, seralarda, bahçe merkezlerinde ve iç mekanlarda ve süslemelerde bir yosun öldürücü, bakterisit, mantar ilac ve herbisit olarak kullanlr. Kaprilik Asit içeren ürünler, çözünür konsantre / svlar ve kullanma hazr svlar olarak formüle edilir. [5] Kaprilik Asit, vücudun enerji girdi ve çkt düzenlemesinde önemli bir rol oynar, bu bir ilevdir. ghrelin hormonu tarafndan gerçekletirilir. Açlk hissi, vücudun gda tüketimi eklinde bir enerji girdisine ihtiyaç duyduunun bir iaretidir. Ghrelin, hipotalamustaki reseptörleri tetikleyerek açl uyarr. Bu reseptörleri aktive etmek için, grelin, bir -OH grubu elde ettii asilasyon ad verilen bir sürece girmelidir ve Kaprilik Asit bunu, grelin molekülleri üzerindeki belirli bir bölgede balanarak salar. Ayn pozisyondaki dier ya asitlerinin açlk üzerinde benzer etkileri vardr. Kaprilik Asit u anda temel titreme için bir tedavi olarak aratrlmaktadr. [6] [7] Kaprilik Asitin (Kaprilik Asit) asit klorürü, perflorooktanoik asit sentezi Kaprilik Asit diyet takviyesi olarak alnr. Vücutta, Kaprilik Asit, oktanoat veya protonsuz Kaprilik Asit olarak bulunur. [8] Baz çalmalar, orta zincirli trigliseritlerin (MCT’ler) ar kalori yakma sürecinde yardmc olabileceini göstermitir. ve dolaysyla kilo kayb; [9] [10] [11] [12] [13] Bununla birlikte, kantlarn sistematik bir incelemesi, genel sonuçlarn yetersiz olduu sonucuna varmtr. [14] Ayrca, dayankllk sporcular ve vücut gelitirme topluluu tarafndan MCT’lere ilgi gösterildi, ancak MCT’lerin egzersiz performansnn iyiletirilmesi için yararl olduu bulunmad. [13] Kaprilik Asit, tedavi edilecek ketojenik diyetin bir parças olarak incelenmitir. Oktanoik asit olarak da adlandrlan Kaprilik Asit, hindistancevizi ya ve hurma yann yan sra baz memelilerin sütünde bulunan yal bir svdr. Boyalar, parfümler, dezenfektanlar ve dezenfeksiyonlarn üretiminde yaygn olarak kullanlan orta zincirli doymu bir ya asididir. Kaprilik Asit ayrca antimikrobiyal ve antienflamatuar özelliklere sahip olduu söylenen diyet takviyeleri olarak formüle edilebilir. . Birçok yalanma önleyici kremde popüler bir bileendir ve kilo kaybna ve atletik performansa yardmc olduuna inanlan bir besin takviyesi olan orta zincirli trigliserit (MCT) yann ana bileenidir. Kaprilik Asit bazen de kullanlr. diyalize giren kiilerde hipoalbüminemiyi (düük albümin) önlemek. Ksmen, iddetli böbrek hastal olan kiilerin sürdürmesi gereken düük proteinli diyet nedeniyle ortaya çkan hipoalbüminemi, diyaliz hastalar için kötü sonuçlarn bir öngörücüsüdür. Kaprilik Asit takviyeleri, genellikle azdan reçetesiz satlan bir takviye olarak satlr. ve vajinal kandidiyazis. Kandidiyaz, koullar Candida albicans mantarlar ile ilikili olan oral pamukçuk ve vajinal maya enfeksiyonlarn tanmlamak için kullanlan tbbi terimdir. 2017’de Journal of Medicinal Food’da yaplan bir aratrma, Caprylic Acid’in (Kaprilik Asit) büyümeyi engelledii sonucuna varmtr. C. albicans’n yaam döngüsünün üç farkl aamasnda hücre geliimini durdurarak test tüpü çalmalarnda yer almaktadr.Popüler olarak kilo verme ürünlerine dahil olan Caprylic Acid’in (Kaprilik Asit) açl bastrarak çaltna inanlmaktadr. nsan vücudunda “açlk hormonu” olan ghrelin mide boaldnda aktive olur. Hem açla katkda bulunan açillenmi grelin hem de glisemik kontrolü iyiletirdiine ve açl bastrdna inanlan açillenmemi grelin vardr. tokluk (dolgunluk hissi). Ancak, PLoS One’da 2015 ylnda yaplan bir çalmada çelikili bir etki rapor edildi.Aratrmaclara göre, Caprilik Asit (Kaprilik Asit) bakmndan zengin bir diyetle beslenen laboratuvar fareleri, asillenmi grelinde art göstermedi, bunun yerine asillenmemi grelinde önemli bir düü yaad. Bunun gibi bulgular, Caprylic Acid’in (Kaprilik Asit) kilo kaybna yardmc olma ihtimalinin düük olduunu göstermektedir. Caprylic Acid’in (Kaprilik Asit) epilepsili kiilerde nöbet saysn azaltmaya yardmc olabileceine dair artan kantlar var. Neurol’da Case Reports’ta yaynlanan 2013 çalmasna göreogical Medicine, Vanderbilt Üniversitesi Tp Merkezi’ndeki doktorlar, tedaviye dirençli epilepsili 43 yandaki bir erkein günde iki kez dört çorba ka MCT ya reçete edildikten sonra nöbetlerde keskin bir azalma yaadn bildirdi. kaprilik, hafif ila orta dereceli Alzheimer hastalnn ilerlemesini yavalatabilir. Nöropsikiyatrik Hastalk ve Tedavi alanndaki çalmalarn 2013 tarihli bir incelemesi, Alzheimer’l yetikinlerin günlük 20 gramlk Kaprilik Asit dozu verilen, bilisel ilevde olmayanlara göre daha yava bir düü yaadn bildirdi. Sonuçlar, Mini-Mental Durum ncelemesi (MMSE) testi kullanlarak izlendi. Kaprilik Asit ayrca, üreticilerin Alzheimer hastalnn tedavisinde yardmc olabileceini iddia ettii Axona adl bir ekin aktif bileenidir. Aama I ve Aama II klinik denemelerine (Axona’nn bir miktar fayda saladn) geçirmelerine ramen, üreticiler Aama III çalmalarn atlamaya ve Axona’y Alzheimer hastalar için bir “tbbi gda” olarak pazarlamaya karar verdiler. Caprylic hakknda daha güçlü kantlar salamak için daha fazla aratrma yaplmas gerekiyor. Asit (Kaprilik Asit) ‘in Alzheimer hastalnn tedavisinde faydalar Kaprilik Asit, Crohn hastal ve tipik olarak daha iddetli ülseratif kolit dahil olmak üzere enflamatuar barsak hastalklarnn (IBD) kontrolüne yardmc olabilir. 2019’da Inflammatory’te yaplan bir aratrmaya göre Günlük 2 gramlk bir Kaprilik Asit dozu olan Barsak Hastal, ülseratif kolitli erikinlerde semptomlarn nüksetmesini önledi. Endoskopik ve doku biyopsisi deerlendirmeleri, ön tedavi deerlerine kyasla barsak yolunun astarnda iltihaplanma ve ülseratif hasarda bir azalma olduunu dorulad. IBD’li kiilerde ar miktarlarda bulunan enflamatuar bir sitokin olan interlökin-8 (IL-8) üretimi. Kaprilik Asit takviyeleri, öngörüldüü ekilde kullanldnda genellikle güvenli kabul edilir. Yaygn yan etkiler mide bulants, ikinlik, kabzlk, mide ekimesi, hazmszlk ve ishaldir. Yüksek dozlar, kalsiyum seviyelerinde anormal bir düüü (hipokalsemi) tetikleyerek çocuklarda büyüme sorunlarna ve osteoporozlu kiilerde artan krlgan kemik riskine neden olabilir. Kaprilik Asit, karacier hastal veya hipotansiyonu (düük) olan kiiler için uygun olmayabilir. Ya asidi almnn artmas olarak her iki durumu da karmaklatrd bilinmektedir. Orta zincirli açil-CoA dehidrojenaz (MCAD) eksiklii olan ve ya asitlerini verimli bir ekilde parçalayamayan kiilerde Kaprilik Asitlerden (Kaprilik Asit) kaçnlmaldr. Caprylic Acid’in (Kaprilik Asit) ar birikmesi hipoglisemiyi (düük kan ekeri), kusmay ve ciddi durumlarda komay tetikleyebilir. Caprylic Acid’in (Kaprilik Asit) çocuklar, hamile kadnlar ve emziren annelerde güvenlii vardr. kurulmad. Güvenlik açsndan, kalifiye çocuk doktoru veya OB / GYN gözetiminde olmadkça Caprylic Acid’den (Kaprilik Asit) kaçnmak en iyisidir. Kaprilik Asit takviyelerinin dier ilaçlarla etkileime girip giremeyecei bilinmemektedir. Kaprilik Asit takviyeleri, eczanelerde, doal gda dükkanlarnda ve diyet takviyeleri konusunda uzmanlam maazalarda da bulunabilir. Kapsüller olarak formüle edildiinde, Kaprilik Asit tipik olarak maya enfeksiyonlarna kar “mantar savunma” takviyesi olarak satlr ve pamukçuk. Bu ürünlerin çou, özel bir Kaprilik Asit eki yerine çok bileenli takviyeler halinde satlmaktadr. Kaprilik Asit veya MCT yann uygun kullanm için hiçbir klavuz bulunmamaktadr. Alzheimer hastalarnda Caprylic Acid’in (Kaprilik Asit) faydalarn aratran çalmalar, bu seviyenin alnmas potansiyel olarak zararl olabilmesine ramen, günde 20 gram (20.000 miligram) kullanmtr. Birlikte formüle edilmi takviyelerin çou, çok daha güvenli bir miktar olan 500 miligram Kaprilik Asit içerir.