CYCLOHEXYLAMINE BENZOATE (SKLOHEKSLAMN BENZOAT)
CYCLOHEXYLAMINE BENZOATE (SKLOHEKSLAMN BENZOAT)
CAS No. : 3129-92-8
EC No. : 221-516-4
Synonyms:
Cyclohexylamine benzoate; Cyclohexanamine benzoate; 3129-92-8; Cyclohexylammonium benzoate; N-Cyclohexylammonium benzoate; Benzoic acid, compd. with cyclohexanamine (1:1); Benzoic acid, compd. with cyclohexylamine (1:1); EINECS 221-516-4; NSC 211025; Benzoic acid, compound with cyclohexylamine (1:1); DTXSID4062856; CTK8I1460; NSC211025; NSC-211025; AS-18085; LS-36679; AX8122786; W0026; Cyclohexylamine Benzoate Solution (Chab Solution); Benzoic acid, compd. with cyclohexylamine (1:1) (8CI); 221-516-4 [EINECS]; 3129-92-8 [RN]; Benzoic acid, compd. with cyclohexanamine (1:1) [ACD/Index Name]; Cyclohexanaminbenzoat (1:1) [German] [ACD/IUPAC Name]; Cyclohexanamine benzoate (1:1) [ACD/IUPAC Name]; Cyclohexanamine benzoate (1:1) [French] [ACD/IUPAC Name]; Cyclohexylammonium benzoate; [3129-92-8]; 4-Amino-N-hydroxy-1-methyl-1H-pyrazole-5-carboxamide [ACD/IUPAC Name]; Benzoic acid, compd. with cyclohexylamine (1:1); Benzoic acid, compd. with cyclohexylamine (1:1) (8CI); Benzoic acid, compound with cyclohexylamine (1:1); BENZOIC ACID; CYCLOHEXANAMINE; BENZOIC ACID; CYCLOHEXYLAMINE; BENZOIC ACID; CYCLOHEXYLAMINE|BENZOIC ACID; CYCLOHEXANAMINE; Cyclohexanamine benzoate; Cyclohexanaminebenzoate; Cyclohexylamine benzoate; Cyclohexylamine Benzoate Solution (Chab Solution); MFCD01744678 [MDL number]; MFCD22572475; N-Cyclohexylammonium benzoate; cyclehexalamine benzoate; cycleheksalamine benzoate; cyclohexalamine benzoate; sikloheksilamin benzoat; sikloheksalamin benzoat; siklohekzilamin benzoat; sikloheksilamin benzot; CYCLEHEXALAMNE BENZOATE; CYCLEHEXALAMINE BENZOATE; CYCLOHEKSALAMNE BENZOATE; CYCLOHEKSALAMINE BENZOATE; CYCLEHEXALAMNE BENZOAT; CYCLEHEXALAMINE BENZOAT; CYCLOHEKSALAMNE BENZOAT
EN
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) IUPAC Name benzoic acid;cyclohexanamine
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) InChI InChI=1S/C7H6O2.C6H13N/c8-7(9)6-4-2-1-3-5-6;7-6-4-2-1-3-5-6/h1-5H,(H,8,9);6H,1-5,7H2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) InChI Key CIFYUXXXOJJPOL-UHFFFAOYSA-N
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Canonical SMILES C1CCC(CC1)N.C1=CC=C(C=C1)C(=O)O
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Molecular Formula C13H19NO2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) CAS 3129-92-8
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) European Community (EC) Number 221-516-4
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) NSC Number 211025
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) DSSTox Substance ID DTXSID4062856
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Physical Description DryPowder
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Molecular Weight 221.29 g/mol
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Hydrogen Bond Donor Count 2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Hydrogen Bond Acceptor Count 3
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Rotatable Bond Count 1
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Exact Mass 221.141579 g/mol
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Monoisotopic Mass 221.141579 g/mol
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Topological Polar Surface Area 63.3 Ų
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Heavy Atom Count 16
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Formal Charge 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Complexity 150
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Isotope Atom Count 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Defined Atom Stereocenter Count 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Undefined Atom Stereocenter Count 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Defined Bond Stereocenter Count 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Undefined Bond Stereocenter Count 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Covalently-Bonded Unit Count 2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Compound Is Canonicalized Yes
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is used as pharmaceutical intermediate,volatile corrosion Inhibitor.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is a white (or colorless) solid with the formula C6H5CO2H. It is the simplest aromatic carboxylic acid. The name is derived from gum benzoin, which was for a long time its only source. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) occurs naturally in many plants[9] and serves as an intermediate in the biosynthesis of many secondary metabolites. Salts of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) are used as food preservatives. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is an important precursor for the industrial synthesis of many other organic substances. The salts and esters of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) are known as benzoates.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) was discovered in the sixteenth century. The dry distillation of gum benzoin was first described by Nostradamus (1556), and then by Alexius Pedemontanus (1560) and Blaise de Vigenère (1596).[10]Justus von Liebig and Friedrich Wöhler determined the composition of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) .[11] These latter also investigated how hippuric acid is related to Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) .In 1875 Salkowski discovered the antifungal abilities of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) , which was used for a long time in the preservation of benzoate-containing cloudberry fruits.[12]It is also one of the chemical compounds found in castoreum. This compound is gathered from the castor sacs of the North American beaver.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is produced commercially by partial oxidation of toluene with oxygen.The first industrial process involved the reaction of benzotrichloride (trichloromethyl benzene) with calcium hydroxide in water, using iron or iron salts as catalyst. The resulting calcium benzoate is converted to Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) with hydrochloric acid. The product contains significant amounts of chlorinated Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) derivatives. For this reason, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) for human consumption was obtained by dry distillation of gum benzoin. Food-grade Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is now produced synthetically.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is cheap and readily available, so the laboratory synthesis of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is mainly practiced for its pedagogical value. It is a common undergraduate preparation.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) can be purified by recrystallization from water because of its high solubility in hot water and poor solubility in cold water. The avoidance of organic solvents for the recrystallization makes this experiment particularly safe. This process usually gives a yield of around 65%.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) and its salts are used as a food preservatives, represented by the E numbers E210, E211, E212, and E213. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) inhibits the growth of mold, yeast[24] and some bacteria. It is either added directly or created from reactions with its sodium, potassium, or calcium salt. The mechanism starts with the absorption of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) into the cell. If the intracellular pH changes to 5 or lower, the anaerobic fermentation of glucose through phosphofructokinase is decreased by 95%. The efficacy of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) and benzoate is thus dependent on the pH of the food.[25] Acidic food and beverage like fruit juice (citric acid), sparkling drinks (carbon dioxide), soft drinks (phosphoric acid), pickles (vinegar) or other acidified food are preserved with Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) and benzoates.Typical levels of use for Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) as a preservative in food are between 0.05–0.1%. Foods in which Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) may be used and maximum levels for its application are controlled by local food laws.Concern has been expressed that Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) and its salts may react with ascorbic acid (vitamin C) in some soft drinks, forming small quantities of carcinogenic benzene.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is a constituent of Whitfield’s ointment which is used for the treatment of fungal skin diseases such as tinea, ringworm, and athlete’s foot.[29][30] As the principal component of gum benzoin, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is also a major ingredient in both tincture of benzoin and Friar’s balsam. Such products have a long history of use as topical antiseptics and inhalant decongestants.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is a precursor to benzoyl chloride, C6H5C(O)Cl by treatment with thionyl chloride, phosgene or one of the chlorides of phosphorus. Benzoyl chloride is an important starting material for several Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) derivates like benzyl benzoate, which is used in artificial flavours and insect repellents.In teaching laboratories, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is a common standard for calibrating a bomb calorimeter.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) occurs naturally as do its esters in many plant and animal species. Appreciable amounts are found in most berries (around 0.05%). Ripe fruits of several Vaccinium species (e.g., cranberry, V. vitis macrocarpon; bilberry, V. myrtillus) contain as much as 0.03–0.13% free Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) . Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is also formed in apples after infection with the fungus Nectria galligena. Among animals, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) has been identified primarily in omnivorous or phytophageous species, e.g., in viscera and muscles of the rock ptarmigan (Lagopus muta) as well as in gland secretions of male muskoxen (Ovibos moschatus) or Asian bull elephants (Elephas maximus).[33] Gum benzoin contains up to 20% of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) and 40% Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) esters.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is an organic compound which is described by the chemical formula C6H5COOH. It consists of a carboxyl group attached to a benzene ring. Therefore, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is said to be an aromatic carboxylic acid. This compound exists as a crystalline, colorless solid under normal conditions. The term ‘benzoate’ refers to the esters and salts of C6H5COOH.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is not very soluble in water. However, the solubility of this compound in water increases when the temperature is increased (as is the case with most compounds). At a temperature of 0 degrees celsius, the solubility of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) in water corresponds to 1.7 grams per litre. When heated to 100 degrees celsius, the solubility of this compound in water increases to 56.31 grams per litre.The commercial production of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is done via the partial oxidation of toluene with oxygen, catalyzed by manganese or cobalt naphthenates. This chemical reaction is illustrated below.Another industrial method of preparing Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is by reacting tri-chlorotoluene with calcium hydroxide in the presence of water, and the treatment of the calcium benzoate product with hydrochloric acid.Although it’s not the most-dangerous chemical you might find in the workplace, proper handling of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is a must to avoid injuries and health risks while on the job.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is a white, crystalline powder with a faint, non-offensive odor. It is a compound naturally found in many plants and is an important precursor for the synthesis of many other organic substances.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) is most commonly found in industrial settings to manufacture a wide variety of products such as perfumes, dyes, topical medications and insect repellents.Cyclohexylamine Benzoate (Sikloheksilamin Benzoat)’s salt (sodium benzoate) is commonly used as a pH adjustor and preservative in food, preventing the growth of microbes to keep food safe. It works by changing the internal pH of microorganisms to an acidic state that is incompatible with their growth and survival.Studies of the subacute toxicity of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) in mice indicated that ingestion of Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) or its sodium salt caused weight loss, diarrhea, irritation of internal membranes, internal bleeding, enlargement of liver and kidney, hypersensitivity, and paralysis followed by death. When Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) (80 mg/kg body weight) and sodium bisulfate (160 mg/kg body weight) or their mixture (Cyclohexylamine Benzoate (Sikloheksilamin Benzoat)/sodim bisulfate = 80 mg/160 mg) were fed to mice for 10 weeks, the death rate was 66% from the mixture and 32% from Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) alone.
TR
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) IUPAC Ad benzoik asit; sikloheksanamin
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) InChI InChI = 1S / C7H6O2.C6H13N / c8-7 (9) 6-4-2-1-3-5-6; 7-6-4-2-1-3-5-6 / h1-5H, (H, 8,9); 6H, 1-5,7H2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) InChI Anahtar CIFYUXXXOJJPOL-UHFFFAOYSA-N
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Kanonik SMILES C1CCC (CC1) N.C1 = CC = C (C = C1) C (= O) O
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Moleküler Formül C13H19NO2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) CAS 3129-92-8
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Avrupa Topluluu (EC) Numaras 221-516-4
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) NSC Numaras 211025
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) DSSTox Madde Kimlii DTXSID4062856
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Fiziksel Tanm Kuru Toz
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Moleküler Arlk 221,29 g / mol
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Hidrojen Ba Donör Says 2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Hidrojen Ba Alc Says 3
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Dönebilen Ba Says 1
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Tam Kütle 221.141579 g / mol
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Monoizotopik Kütle 221.141579 g / mol
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Topolojik Polar Yüzey Alan 63.3 Ų
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Ar Atom Says 16
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Resmi arj 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Kompleksitesi 150
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) zotop Atom Says 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Tanml Atom Stereocenter Says 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Tanmsz Atom Stereocenter Says 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Tanml Ba Stereocenter Says 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Tanmsz Ba Stereocenter Says 0
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Kovalent Bal Birim Says 2
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) Bileii Kanonikalize Edilmitir Evet
Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) farmasötik ara, uçucu korozyon inhibitörü olarak kullanlr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), C6H5CO2H formülüne sahip beyaz (veya renksiz) bir katdr. En basit aromatik karboksilik asittir. sim, uzun süredir tek kayna olan sakz benzoinden türetilmitir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) birçok bitkide doal olarak bulunur [9] ve birçok ikincil metabolitin biyosentezinde bir ara ürün görevi görür. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) tuzlar gda koruyucu olarak kullanlr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), dier birçok organik maddenin endüstriyel sentezi için önemli bir öncüdür. Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) tuzlar ve esterleri benzoatlar olarak bilinir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) on altnc yüzylda kefedildi. Sakz benzoinin kuru damtlmas ilk olarak Nostradamus (1556) ve ardndan Alexius Pedemontanus (1560) ve Blaise de Vigenère (1596) tarafndan tanmland. [10] Justus von Liebig ve Friedrich Wöhler, Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) bileimini belirledi. [11] Bunlar ayrca hippurik asidin Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ile nasl ilikili olduunu aratrd. 1875’te Salkowski, benzoat içerenlerin korunmasnda uzun süre kullanlan Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) antifungal yeteneklerini kefetti. Cloudberry meyveleri. [12] Ayrca castoreum’da bulunan kimyasal bileiklerden biridir. Bu bileik, Kuzey Amerika kunduzunun kastor keselerinden elde edilir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), ticari olarak toluenin oksijen ile ksmi oksidasyonu ile üretilir. katalizör olarak demir veya demir tuzlarnn kullanlmas. Elde edilen kalsiyum benzoat, hidroklorik asit ile Sikloheksilamin Benzoata (Sikloheksilamin Benzoat) dönütürülür. Ürün, önemli miktarda klorlu Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) türevleri içerir. Bu nedenle insan tüketimi için Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), benzoinin kuru damtlmasyla elde edilmitir. Gda snf Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) artk sentetik olarak üretilmektedir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ucuzdur ve kolayca temin edilebilir, bu nedenle Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) laboratuar sentezi esas olarak pedagojik deeri için uygulanr. Yaygn bir lisans hazrlktr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), scak suda yüksek çözünürlüü ve souk suda zayf çözünürlüü nedeniyle sudan yeniden kristalletirme yoluyla saflatrlabilir. Yeniden kristalletirme için organik çözücülerden kaçnlmas, bu deneyi özellikle güvenli hale getirir. Bu ilem genellikle% 65 civarnda bir verim verir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ve tuzlar, E210, E211, E212 ve E213 ile temsil edilen gda koruyucular olarak kullanlr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) küf, maya [24] ve baz bakterilerin büyümesini engeller. Ya dorudan eklenir ya da sodyum, potasyum veya kalsiyum tuzu ile reaksiyonlardan oluturulur. Mekanizma, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ‘n hücreye emilimi ile balar. Hücre içi pH 5 veya daha düük olarak deiirse, glukozun fosfofruktokinaz yoluyla anaerobik fermantasyonu% 95 orannda azalr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ve benzoatn etkinlii bu nedenle gdann pH’na baldr. [25] Meyve suyu (sitrik asit), gazl içecekler (karbondioksit), alkolsüz içecekler (fosforik asit), turu (sirke) veya dier asitlenmi yiyecekler gibi asidik yiyecek ve içecekler Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ve benzoatlarla korunur. Gdalarda koruyucu olarak Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) için% 0,05–0,1 arasndadr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ‘n kullanlabilecei gdalar ve uygulamas için maksimum seviyeler yerel gda kanunlar tarafndan kontrol edilmektedir. alkolsüz içecekler, az miktarda kanserojen benzen oluturur. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), tinea, saçkran ve ayak mantar gibi mantar cilt hastalklarnn tedavisinde kullanlan Whitfield merheminin bir bileenidir. [29] [30] Zamk benzoinin ana bileeni olan Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), hem benzoinin hem de Friar’n balzamnn tentüründe önemli bir bileendir. Bu tür ürünler, topikal antiseptikler ve inhalant dekonjestanlar olarak uzun bir kullanm geçmiine sahiptir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), tiyonil klorür, fosgen veya fosfor klorürlerinden biri ile ilenerek benzoil klorür, C6H5C (O) Cl’nin öncüsüdür. Benzoil klorür, yapay aromalarda ve böcek kovucularda kullanlan benzil benzoat gibi çeitli Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) türevleri için önemli bir balangç malzemesidir.Laboratuvarlar eitirken, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), bir bomba kalorimetresini kalibre etmek için yaygn bir standarttr. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), birçok bitki ve hayvan türünde esterleri gibi doal olarak bulunur. Çou meyvede takdire ayan miktarlar bulunur (yaklak% 0,05). Birkaç Vaccinium türünün olgun meyveleri (örn. Kzlck, V. vitis macrocarpon; bilberry, V. myrtillus)% 0,03–0,13 orannda serbest Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) içerir. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ayrca Nectria galligena mantar ile enfeksiyondan sonra elmalarda oluur. Hayvanlar arasnda, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) öncelikle omnivor veya fitofajl türlerde, örnein kaya ptarmigan’n (Lagopus muta) iç organlarnda ve kaslarnda ve erkek muskoxen (Ovibos moschatus) veya Asya boa fillerinin salg bezlerinde tanmlanmtr. (Elephas maximus). [33] Sakz benzoin,% 20’ye kadar Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ve% 40 Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) esterleri içerir.yclohexylamine Benzoate (Sikloheksilamin Benzoat), kimyasal formül C6H5COOH ile tanmlanan organik bir bileiktir. Bir benzen halkasna bal bir karboksil grubundan oluur. Bu nedenle, Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) aromatik bir karboksilik asit olduu söylenir. Bu bileik, normal koullar altnda kristalli, renksiz bir kat olarak bulunur. “Benzoat” terimi, C6H5COOH’un esterlerini ve tuzlarn ifade eder. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), suda çok fazla çözünmez. Bununla birlikte, bu bileiin sudaki çözünürlüü, scaklk arttnda artar (çou bileikte olduu gibi). 0 santigrat derece scaklkta, Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) sudaki çözünürlüü litre bana 1.7 grama karlk gelir. 100 santigrat dereceye kadar stldnda, bu bileiin sudaki çözünürlüü litre bana 56.31 grama yükselir. Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) ticari üretimi, toluenin manganez veya kobalt naftenatlarla katalize edilen oksijenle ksmi oksidasyonu yoluyla yaplr. Bu kimyasal reaksiyon aada gösterilmitir: Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) hazrlamann bir baka endüstriyel yöntemi, tri-klorotoluenin su varlnda kalsiyum hidroksit ile reaksiyona sokulmas ve kalsiyum benzoat ürününün hidroklorik asit ile ilenmesidir. – yerinde bulabileceiniz tehlikeli kimyasal, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) ‘n uygun ekilde kullanlmas, i srasnda yaralanmalar ve salk risklerini önlemek için bir zorunluluktur. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), soluk, – rahatsz edici koku. Birçok bitkide doal olarak bulunan bir bileiktir ve dier birçok organik maddenin sentezi için önemli bir öncüdür. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat), parfümler, boyalar, topikal gibi çok çeitli ürünleri üretmek için en yaygn olarak endüstriyel ortamlarda bulunur. ilaçlar ve böcek kovucular. Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) tuzu (sodyum benzoat), gdalar güvende tutmak için mikroplarn büyümesini önleyerek gdalarda pH ayarlayc ve koruyucu olarak yaygn olarak kullanlr. Mikroorganizmalarn iç pH’n, büyümeleri ve hayatta kalmalar ile uyumlu olmayan asidik bir duruma deitirerek çalr. Farelerde Sikloheksilamin Benzoat’n (Sikloheksilamin Benzoat) subakut toksisitesi üzerine yaplan aratrmalar, Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) veya sodyum tuzunun yutulduunu göstermitir. kilo kaybna, ishale, iç zarlarn tahri olmasna, iç kanamaya, karacier ve böbrein genilemesine, ar duyarlla ve felce ve ardndan ölüme neden oldu. Farelere Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) (80 mg / kg vücut arl) ve sodyum bisülfat (160 mg / kg vücut arl) veya bunlarn karm (Cyclohexylamine Benzoate (Sikloheksilamin Benzoat) / sodim bisülfat = 80 mg / 160 mg) verildiinde 10 hafta boyunca, ölüm oran karmdan% 66 ve tek bana Sikloheksilamin Benzoattan (Sikloheksilamin Benzoat)% 32 idi.