ETHYLHEXYL SALICYLATE (ETLHEKZL SALSLAT)
ETHYL HEXYL SALICYLATE (ETL HEKZL SALSLAT)
CAS NUMBER: 118-60-5
EC NUMBER: 204-263-4
SYNONYMS: OCTISALATE; ETHYLHEXYL SALICYLATE, 2-ETHYLHEXYL 2-HYDROXYBENZOATE; 2-ETHYLHEXYL ESTER BENZOIC ACID, 2-HYDROXY-; 2-ETHYLHEXYL ESTER SALICYLIC ACID; 2-ETHYLHEXYL SALICYLATE; 2-HYDROXY- 2-ETHYLHEXYL ESTER BENZOIC ACID; 3-10-00-00124 (BEILSTEIN HANDBOOK REFERENCE) ; BENZOIC ACID, 2-HYDROXY-, 2-ETHYLHEXYL ESTER; BENZOIC ACID, 2HYDROXY, 2ETHYLHEXYL ESTER; BRN 2730664; EHS; EINECS 204-263-4; Ethylhexyl Salicylate; Octisalate; 2-ethylhexyl salicylate; ethyl hexyl salicylate; octisalate; octylsalicylate; salicylic acid 2-ethylhexyl ester; trans-2-hexenyl salicylate; 2-ETHYLHEXYL SALICYLATE; Octisalate; 118-60-5; 2-Ethylhexyl 2-hydroxybenzoate; Sunarome O; Sunarome WMO; Ethyl hexyl salicylate; Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; USAF DO-11; Salicylic acid, 2-ethylhexyl ester; NSC 46151; Salicylic Acid 2-Ethylhexyl Ester; EINECS 204-263-4; Ethylhexyl salicylate; BRN 2730664; WMO; CHEBI:88639; FMRHJJZUHUTGKE-UHFFFAOYSA-N; FR-2110; NCGC00159324-02; AK114524; SSTox_CID_20734; DSSTox_RID_79578; DSSTox_GSID_40734; CAS-118-60-5; Octisalate [USAN]; Octisalate [USAN:USP:INN]; Dermoblock OS; Neo Heliopan OS; isooctyl salicylate; Uvinul (TN); Escalol 587; Uvinul O-18; 2-Hydroxybenzoic acid 2-ethylhexyl ester; Octisalate (USP/INN); Ethylhexyl salicylic acid; AC1L1QUB; ACMC-2099xq; Salicylic Acid Octyl Ester; EC 204-263-4; Salicylic acid 2-ethylhexyl; SCHEMBL39594; 2-Ethylhexyl salicylate, 99%; CHEMBL1329203; DTXSID7040734; STOCK3S-17209; CTK0H4936; 2-ethylhexyl ester salicylic acid; MolPort-002-239-441; WLN: QR BVO1Y4 & 2; 2-Ethylhexyl salicylate, >=99%; HY-B0929; KS-00000WA8; NSC46151; Tox21_111573; ANW-17148; MFCD00053300; NSC-46151; SBB008473; AKOS015890505; Salicylic acid-2-ethyl-1-hexyl ester; Tox21_111573_1; CS-4398; MCULE-8560679857; RL00714; RTR-003182; TRA0028437; NCGC00159324-03; NCGC00159324-04; AC-12458; AN-22786; BC204665; CC-10526; LP003006; LP028355; SC-19045; 2-hydroxy benzoic acid 2-ethylhexyl ester; 2-hydroxy- 2-ethylhexyl ester benzoic acid; AX8074693; KB-230435; LS-144331; ST2416863; TR-003182; 2-ethylhexyl ester benzoic acid, 2-hydroxy-Ethylhexyl salicylate, analytical standard; FT-0631674; S0387; ST50319550; benzoic acid, 2-hydroxy, 2-ethylhexyl ester; D05226; C-28044; I01-6463; J-509330; Octisalate, United States Pharmacopeia (USP) Reference Standard; Octisalate, Pharmaceutical Secondary Standard; Certified Reference Material; 194304-34-2; 8014-40-2; Ethylhexyl Salicylate; Salicylic Acid, Calcium Salicylate, Magnesium Salicylate, MEA-Salicylate, Potassium Salicylate, Sodium Salicylate; Skin conditioning agent – miscellaneous – Salicylic Acid, Butyloctyl Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Tridecyl Salicylate; 2-Ethylhexyl salicylate; Octisalate; Octyl salicylate; Linear Formula (HO)C6H4CO2CH2CH(C2H5)(CH2)3CH3; Molecular Weight 250.33; MDL number MFCD00053300; FMRHJJZUHUTGKE-UHFFFAOYSA-N; 2-Ethylhexyl salicylate; analytical standard; Octisalate; Octyl salicylate; ETHYLHEXYL SALICYLATE; 2-Ethylhexyl salicylate; ethyl hexyl salicylate; octisalate; octyl salicylate; 2-Ethylhexyl salicylate; Octyl Salicylate; 2-Ethylhexyl salicylate; InChI=1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3; IUPAC Standard InChIKey: FMRHJJZUHUTGKE-UHFFFAOYSA-N; Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; Salicylic acid, 2-ethylhexyl ester; Sunarome O; Sunarome WMO; USAF DO-11; WMO; Dermoblock OS; Escalol 587; Ethylhexyl salicylate; Neo Heliopan OS; Octyl salicylate; Uvinul O-18; 2-Ethylhexyl 2-hydroxybenzoate; NSC 46151; Octisalate; 194304-34-2; 8014-40-2; octyl salicylate; CCCCC(CC)COC(=O)C1=CC=CC=C1O; InChI Identifier; InChI=1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3; InChI Key; FMRHJJZUHUTGKE-UHFFFAOYSA-N; O-hydroxybenzoic acid ester; Salicylic acid or derivatives; Benzoyl; 1-hydroxy-4-unsubstituted benzenoid; 1-hydroxy-2-unsubstituted benzenoid; Phenol; Vinylogous acid; Carboxylic acid ester; Monocarboxylic acid or derivatives; Carboxylic acid derivative; Organic oxygen compound; Organic oxide; Hydrocarbon derivative; Organooxygen compound; Aromatic homomonocyclic compound; Homomenthyl salicylate (homosalate); Ethylhexyl salicylate; octyl salicylate; Trolamine salicylate; Benzyl salicylate; Amyl salicylate; Phenyl salicylate; (2S)-2-Ethylhexyl salicylate; (2S)-2-Ethylhexyl salicylate [ACD/IUPAC Name]; (2S)-2-Ethylhexylsalicylat [German] [ACD/IUPAC Name]; Benzoic acid, 2-hydroxy-, (2S)-2-ethylhexyl ester [ACD/Index Name]; Salicylate de (2S)-2-éthylhexyle [French] [ACD/IUPAC Name]; [(2S)-2-ethylhexyl] 2-hydroxybenzoate; [(2S)-2-ethylhexyl] 2-oxidanylbenzoate; 204-263-4 [EINECS]; 2-hydroxybenzoic acid [(2S)-2-ethylhexyl] ester; octisalate [INN]; UNII-4X49Y0596W; 2-Ethylhexyl salicylate (CAS 118-60-5); 2-Ethylhexyl 2-hydroxybenzoate; Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; Dermoblock OS; Escalol 587; Ethylhexyl salicylate; NSC 46151; Neo Heliopan OS; Octisalate; Octyl salicylate; Salicylic acid, 2-ethylhexyl ester; Sunarome O; Sunarome WMO; USAF DO-11; Uvinul O-18; WMO; InChI; InChI=1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3;nChI Key; FMRHJJZUHUTGKE-UHFFFAOYSA-N; Formula; C15H22O3; SMILES; CCCCC(CC)COC(=O)c1ccccc1O; 2-ethylhexyl salicylate; 2-Ethylhexyl salicylate – CAS 118-60-5; 2-hydroxy-benzoicaci2-ethylhexylester;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;Benzoicacid,2-hydroxy-,2-ethylhexylester;Dermoblock OS;Escalol 587;Ethylhexyl salicylate; [(2R)-2-ethylhexyl] 2-hydroxybenzoate; 2-ethylhexyl 2-hydroxybenzoate; benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; 2-ethyl hexyl 2-hydroxybenzoate; ethyl hexyl salicylate; ethylhexyl (octyl) salicylate; 2- ethylhexyl 2-hydroxybenzoate; 2-ethylhexyl salicylate; filtrosol C; 2-hydroxybenzoic acid 2-ethyl hexyl ester; megasol-complex (Vevy); neo heliopan OS (Symrise); octisalate; Octyl salicylate; 2-octyl salicylate; salicylic acid 2-ethyl hexyl ester; salicylic acid 2-ethylhexyl ester salicylic acid; 2-ethylhexyl ester; salotan; sunarome; sunarome O; YOS E; Ethylhexyl Salicylate; Octisalate; 2-Ethylhexyl salicylate; WMO;usafdo-11;USAF do-11;Sunarome O;EUSOLEX OS;OCTISALATE;Escalol 587;Uvinul O-18;Sunarome WMO;Dermoblock OS; NIST; Chemistry ReferenceSalicylic acid, 2-ethylhexyl ester(118-60-5); EPA Substance; Registry System; Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester(118-60-5); 2-ethylhexyl 2-hydroxybenzoate; 2-hydroxybenzoate de 2-éthylhexyle; Ethylhexyl salicylate; CHEBI:88639; Ethylhexyl salicylate; 2-Ethylhexyl salicylate ≥98.0%; Salicylic Acid 2-Ethylhexyl Ester, Octyl Salicylate, Salicylic Acid Octyl Ester; CAS Number: 118-60-5; MDL Number: MFCD00053300; Molecular Formula: C15H22O3; Molecular Weight: 250.34; Purity/Analysis Method: 98.0% (GC); 2-Ethylhexyl Salicylate; （CAS Number：118-60-5; Product Number：S0387); Octyl Salicylate; Salicylic Acid 2-Ethylhexyl Ester; Salicylic Acid Octyl Ester; Ethylhexyl Salicylate – EHS; Ethylhexyl Salicylate; Octisalate; 2-ethylhexyl salicylate; Octyl Salicylate; 2-Ethylhexyl Salicylate; Ethylhexyl Salicylate; Octyl salicylate; 2-Ethylhexyl salicylate; Octisalate, Trade name is Escalol 587; Octyl Salicylate; (2 Ethylhexyl Salicylate); Ethylhexyl Salicylate; octyl salicylate (octisalate); octyl salicylate (octisalate); Ethylhexyl Salicylate; 2-ETHYLHEXYL SALICYLATE; 2-ETHYLHEXYL SALICYLATE; Part #:NG-16542-1G; CAS: 118-60-5; 2-ETHYLHEXYL SALICYLATE; EI-B; MS; (HO)C6H4COOCH2(C2H5)CH(CH2)3CH3; Salicylic acid, 2-ethylhexyl ester; Benzoic acid, o-hydroxy-, Octyl ester; N-Octyl o-hydroxybenzoate; 2-Ethylhexyl salicylate; 2-hydroxy-Benzoic acid; 2-ethylhexyl ester; Octyl Salicylate 2-Ethylhexyl Salicylate; 2-Ethylhexyl salicylate, 95%; 2-Ethylhexyl salicylate, 0.97; 2-Ethylhexyl Salicylate; Octisalate, 98%; 2-Ethylhexyl salicylate, 98%; 2-Ethylhexyl salicylate, 98+%; 2-Ethylhexyl salicylate; 2-Ethylhexyl salicylate, 98%; Octyl salicylate; 2-Ethylhexyl salicylate; Octyl salicylate; Octyl salicylate; 2-Ethylhexyl Salicylate; Octisalate, USP, 95.0-105.0%; octyl salicylate, 98.5%Min.; Octyl salicylate; 2-Ethylhexylsalicylate; Salicylic acid 2-ethylhexyl ester; 98%; Octyl salicylate, 99,00%; Octyl salicylate; 2-Ethylhexyl salicylate; Ethylhexyl Salicylate; OKTL SALSLAT; OKTIL SALISILAT; OKTIL; SALISILAT; OKTL; SALSLAT; ETL HEGZL SALSLAT; ETIL HEGZIL SALISILAT; ETL HEKZL SALSLAT; ETIL HEKZIL SALISILAT; 2-ethylhexyl 2-hydroxybenzoate; 2-ethylhexyl salicylate; ethyl hexyl salicylate; octisalate; octylsalicylate; salicylic acid 2-ethylhexyl ester; trans-2-hexenyl salicylate; 2-ETHYLHEXYL SALICYLATE; 118-60-5; Octisalate; 2-Ethylhexyl 2-hydroxybenzoate; Sunarome O; Sunarome WMO; Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester; Ethyl hexyl salicylate; USAF DO-11; Salicylic acid, 2-ethylhexyl ester; NSC 46151; EINECS 204-263-4; BRN 2730664; WMO; CHEBI:88639; FMRHJJZUHUTGKE-UHFFFAOYSA-N; Salicylic Acid 2-Ethylhexyl Ester; Ethylhexyl salicylate; FR-2110; NCGC00159324-02; AK114524; DSSTox_CID_20734; DSSTox_RID_79578; DSSTox_GSID_40734; CAS-118-60-5; Octisalate [USAN]; Octisalate [USAN:USP:INN]; Dermoblock OSi; Neo Heliopan OS; isooctyl salicylate; Uvinul (TN); Escalol 587; Uvinul O-18; Octisalate (USP/INN); AC1L1QUB; ACMC-2099xq; Salicylic Acid Octyl Ester; EC 204-263-4; Salicylic acid 2-ethylhexyl; SCHEMBL39594; 2-Ethylhexyl salicylate, 99%; CHEMBL1329203; 2-ethylhexyl ester salicylic acid; MolPort-002-239-441; WLN: QR BVO1Y4 & 2; 2-Ethylhexyl salicylate, >=99%; HY-B0929;AakoSun EHS; ETL HEKZL SALSLAT; etil hekzil salisilat; 2-etil hekzil salisilat; oktisalat; oktilsalisilat; oktilsalat; etil hegzil salisilat; hekzil
Octisalate is a sunscreen ingredient with a generally good safety profile. It can stabilize avobenzone and result in longer-lasting sun protection. Ethylhexyl salicylate (also known as Octyl Slicylate) is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB rays from the sun. Ethylhexyl salicylate (also known as Octyl Slicylate) is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB rays from the sun, according to Wikipedia. Ethylhexyl salicylate is a colorless liquid with an oily consistency that often emits a mildly floral fragrance. Octyl Salicylate (OS) is commonly incorporated into sunscreens for its antibacterial abilities and helps prevent products from turning rancid. It is an oil soluble and water insoluble UVB absorber which has been used for a long time, even before PABA. It provides effective protection in the range of 290-315 nm. It is generally used in combination with other UV Absorbers to boost the SPF. It serves as an inhibitor against UV degradation of emulsions, polymer and dyestuff. It is ideal for use in sun care and skin care products for daily protection. OS is an exceptional addition to protective hair-care and lip-care products. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. It appears to have comparatively good safety profile. However, used alone it is insufficient even for UVB protection.
Ethylhexyl salicylate is an ester formed by the condensation of a salicylic acid with 2-ethylhexanol. The salicylate component absorbs ultraviolet light and protects the skin from the harmful effects of exposure to sunlight. The ethylhexanol portion serves as a fatty alcohol, adding emollient and oil-like (water resistant) properties.
Salicylic Acid is sometimes called a beta hydroxy acid (abbreviated BHA) that can be obtained from the bark of willow trees. The salts of Salicylic Acid (Calcium Salicylate, Magnesium Salicyalte, MEA-Salicylate, Potassium Salicylate, Sodium Salicylate, TEA-Salicylate) and the esters of Salicylic Acid (Butyloctyl Salicylate, C12-15 Alkyl Salicylate, Capryolyl Salicylic Acid, Hexyldecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Ethylhexyl Salicylate, Methyl Salicylate, Myristyl Salicylate, Tridecyl Salicylate) may also be used in cosmetics and personal care products. As Salicylic Acid and its salts and esters have many functions, these ingredients may be used in many types of cosmetics and personal care products including moisturizers, skin cleansing products, shampoos, as well as skin care, hair care, suntan and sunscreen products, as well as in mouthwashes and dentifrices.
Ethylhexyl salicylate, or octyl salicylate, is an organic compound used as an ingredient in sunscreens and cosmetics to absorb UVB (ultraviolet) rays from the sun. It is an ester formed by the condensation of a salicylic acid with 2-ethylhexanol. It is a colorless oily liquid with a slight floral odor. 2-Ethylhexyl salicylate could be commonly used in cosmetics and sunscreens acting as a skin penetration enhancer and could absorb UVB rays at some extent.
UV-B adsorbing agent in sunscreen cosmetics of the type creams, lotions, lipsticks, sun oils, etc. Salicylates effectively absorb light throughout the UVB range but absorb little or no UVA light. Salicylate sunscreens may therefore be used to prevent sunburn, but are unlikely to prevent drug-related or other photosensitivity reactions associated with UVA light; combination with a benzophenone may give some added protection. Octyl Salicylate (OS) is commonly incorporated into sunscreens for its antibacterial abilities and helps prevents the product from turning rancid. It is an oil soluble and water Insoluble UV B absorber which is being used for a long time, even before PABA and provides effective protection in the range of 290-315 nm. Salicylates are weak UV B absorber and generally used in combination with other UV to boost the SPF. OS serves as an inhibitor against UV degradation of emulsions, polymer, and dyestuff. OS is ideal for use in sun care and skin care products for daily protection. OS is an exceptional addition to protective hair-care and lip-care products.
Salicylic Acid is a white crystalline powder or needle-shaped crystals with sweetish taste; soluble in acetone, ether, alcohol, boiling water, benzene and turpentine, sparingly soluble in chloroformbenzene, slightly soluble in water; melts at 158°C. The sodium salt form (sodium salicylate) is common commercially, prepared from mainly sodium phenolate with carbon dioxide under heating and pressure. It contains both a hydroxyl and a carboxyl group, which react with either an acid or an alcohol. The carboxyl group forms esters with alcohols; e.g. methyl salicylate is formed with methanol, which used in food flavorings and preservatives; menthyl salicylate is formed with methanol, which is used in suntan lotions. The hydroxyl group reacts with acetic acid to form acetylsalicylic acid (called aspirin) which is the most widely common antiseptic and antipyretic agent. Phenyl salicylate (called salol) is formed with phenol, which is also used as an antiseptic and antipyretic agent. The sodium salt (Sodium salicylate), a shiny white powder, is used for antiseptics preparations and as a preservative. In addition to its analgesic and antipyretic properties, salicylic acid possesses keratinolytic properties and fungicidal properties. It ans its derivatives are used in the treatment of hyperkeratotic, dandruff, ichthyosis and psoriasis as well as in the treatment of fungal skin infections such as tinea. Para-Aminosalicylic acid (abbreviated PAS and PASA) is an analogue of para-aminobenzoic acid (abbreviated PABA) that inhibits folic acid synthesis in Mycobacterium tuberculosis and is bacteriostatic, inhibits growth and multiplication of the tubercle bacillus. Para-Aminosalicylic acid and its sodium salt (sodium p-Aminosalicylate) are bacteriostatic against mycobacteria and used in the treatment of tuberculosis; administered orally. Brand names are Tubasal, Nemasol Sodium and etc. Aminosalicylic acids are pharmaceutically active ingredients including anti-infectives against colds, flu, or other virus infections. Mesalamine (5-aminosalicylic acid, abbreviated 5-ASA) an active metabolite of sulfasalazine, used to treat inflammation of the rectum and lower colon, mild to moderate ulcerative colitis proctosigmoiditis, and proctitis. Para-Aminosalicylic acid (4-hydroxybenzoic acid) is used as an intermediate of bacteriostatic agent specially for parabens (alkyl esters of p-hydroxy benzoic acid) which used in food and personal care products as a preservative. It is applied in the production of liquid crystal polymers. It is also used as an intermediate of dyes, insecticides, pharmaceutical, pesticides and other chemical compounds. Salicylic Acid and its derivatives are important for the preparation of other pharmaceutical products, dyes, flavours, and preservatives.
Octisalate, genel olarak iyi bir güvenlik profiline sahip bir güne koruyucu bileenidir. Avobenzone’u stabilize edebilir ve daha uzun süreli güne korumasyla sonuçlanabilir. Etilheksil salisilat (Octyl Slicylate olarak da bilinir), güneten gelen UVB nlarn güneten almak için güne koruyucu maddeler ve kozmetikler olarak kullanlan bir organik bileiktir. Etilheksil salisilat (Octyl Slicylate olarak da bilinir), Vikipedi’ye göre güneten ve UVB nlarn güneten emmek için kozmetik olarak kullanlan bir organik bileiktir. Etilheksil salisilat, genellikle hafifçe çiçeksi bir koku veren yal bir kvama sahip renksiz bir svdr. Octyl Salicylate (OS), antibakteriyel kabiliyetleri için genellikle güne koruyucularna dahil edilir ve ürünlerin rancid dönmesini engellemeye yardmc olur. PABA’dan önce bile uzun süre kullanlm olan yada çözünen ve suda çözünmeyen bir UVB emicidir. 290-315 nm aralnda etkili koruma salar. Genellikle SPF’yi güçlendirmek için dier UV Emicilerle birlikte kullanlr. Emülsiyonlarn, polimerin ve boyarmaddenin UV bozunmasna kar bir inhibitör görevi görür. Günlük koruma için güne bakm ve cilt bakm ürünlerinde kullanm için idealdir. OS koruyucu saç bakm ve dudak bakm ürünleri için olaanüstü bir ektir. Octil salisilat, UVB radyasyonunu emen, yada çözünebilen bir kimyasal güne koruyucu maddedir. UVA’ya kar koruma salamaz. Nispeten iyi bir güvenlik profiline sahip görünüyor. Bununla birlikte, tek bana kullanldnda, UVB korumas için bile yetersizdir.
Etilheksil salisilat, bir salisilik asidin 2-etilheksanol ile younlatrlmasyla oluturulan bir esterdir. Salisilat bileeni ultraviyole emer ve cildi güne na maruz kalmann zararl etkilerinden korur. Etilheksanol ksm, bir yal alkol olarak, yumuatc ve yaa benzer (suya dayankl) özellikler ekleyerek çalr. Salisilik Asit bazen söüt aaçlarnn kabuundan elde edilebilen bir beta hidroksi asit (ksaltlm BHA) olarak adlandrlr. Salisilik Asit (Kalsiyum Salisilat, Magnezyum Salisilat, MEA-Salisilat, Potasyum Salisilat, Sodyum Salisilat, TEA Salisilat) ve Salisilik Asit (Butiloksil Salisilat, C12-15 Alkil Salisilat, Kapriolil Salisilik Asit, Heksildesil Salisilat, zosetil’in esterleri Kozmetik ve kiisel bakm ürünlerinde Salisilat, zodesil Salisilat, Etilheksil Salisilat, Metil Salisilat, Myristyl Salisilat, Tridesil Salisilat) kullanlabilir. Salisilik Asit ve onun tuzlar ve esterleri birçok fonksiyona sahip olduundan, bu içerikler nemlendirici maddeler, cilt temizleme ürünleri, ampuanlar ve ayn zamanda cilt bakm, saç bakm, güne kremi ve güne kremi ürünleri gibi birçok türde kozmetik ve kiisel bakm ürünlerinde kullanlabilir. gargaralarda ve di macunlarnda olduu gibi. Etilheksil salisilat veya oktil salisilat, güneten gelen UVB (ultraviyole) nlar absorbe etmek için güne koruyucular ve kozmetikler içinde bir bileen olarak kullanlan organik bir bileiktir. Bir salisilik asidin 2-etilheksanol ile younlatrlmasyla oluturulan bir esterdir. Hafif çiçek kokulu renksiz yal bir svdr. 2-Etilheksil salisilat, kozmetikte ve güneten koruyucularda yaygn olarak kullanlr ve cilt penetrasyon arttrc olarak görev yapar ve bir dereceye kadar UVB nlarn emebilir.
Kremler, losyonlar, rujlar, güne yalar vb. Güne koruyucu kozmetiklerde UV-B adsorpsiyon ajan. Salisilatlar, UVB aral boyunca etkili bir ekilde emer, ancak çok az UVA absorbe eder. Salisilat güne koruyucular bu nedenle güne yannn önlenmesi için kullanlabilir, ancak UVA ile ilikili ilaca bal veya dier fotosensitivite reaksiyonlarn önlemek için olas deildir; Bir benzofenon ile kombinasyon baz ilave koruma salayabilir. Octyl Salicylate (OS), antibakteriyel yetenekleri için güne koruyucularna yaygn olarak dahil edilir ve ürünün sradan dönmesini önler. PABA’dan önce bile uzun bir süre boyunca kullanlan ve 290-315 nm aralnda etkili koruma salayan bir yada çözünen ve suda çözünmeyen UV B emicidir. Salisilatlar zayf UV B emicidir ve genellikle SPF’yi arttrmak için dier UV ile kombinasyon halinde kullanlr. OS, emülsiyonlarn, polimerin ve boyarmaddenin UV bozunmasna kar bir inhibitör görevi görür. letim sistemi günlük koruma için güne bakm ve cilt bakm ürünlerinde kullanm için idealdir. OS koruyucu saç bakm ve dudak bakm ürünleri için olaanüstü bir ektir.
Salisilik Asit, beyaz kristalli bir toz veya ekerli tad olan ine ekilli kristallerdir; aseton, eter, alkol, kaynar su, benzen ve terpantin içinde çözünür, kloroformbenzen içinde az çözünür, suda az çözünür; 158 ° C’de erir. Sodyum tuzu formu (sodyum salisilat), yaygn olarak sodyum fenolattan, karbon dioksit ile stma ve basnç altnda hazrlanan ticari olarak yaygndr. Hem bir asit hem de alkol ile reaksiyona giren bir hidroksil ve bir karboksil grubunu içerir. Karboksil grubu, esterleri alkoller ile oluturur; Örnein. metil salisilat, gda aromalar ve koruyucu maddelerde kullanlan metanol ile oluturulur; mentlü salisilat, güne losyonlarnda kullanlan metanol ile oluturulur. Hidroksil grubu asetik asit ile reaksiyona girerek asetilsalisilik asidi (aspirin olarak adlandrlr) oluturur, ki bu en yaygn antiseptik ve antipeptik ajandr. Ayn zamanda bir antiseptik ve antipiretik madde olarak kullanlan fenol ile fenil salisilat (salol olarak adlandrlr) oluur. Parlak beyaz bir toz olan sodyum tuzu (Sodyum salisilat) antiseptik preparatlar ve koruyucu olarak kullanlr. Analjezik ve antipiretik özelliklerine ek olarak, salisilik asit keratinolitik özelliklere ve mantar öldürücü özelliklere sahiptir. Bu türevler, hiperkeratotik, kepek, iktiyoz ve sedef hastalnn tedavisinde ve ayn zamanda tinea gibi fungal cilt enfeksiyonlarnn tedavisinde kullanlmaktadr. Para-Aminosalisilik asit (ksaltlm PAS ve PASA), Mycobacterium tuberculosis’te folik asit sentezini inhibe eden ve bakteriyostatik olan, tüberküloz basilinin büyümesini ve çoalmasn inhibe eden para-aminobenzoik asidin (ksaltlm PABA) bir analogudur. Para-Aminosalisilik asit ve sodyum tuzu (sodyum p-Aminosalisilat) mikobakterilere kar bakteriyostatiktir ve tüberküloz tedavisinde kullanlr; oral yoldan uygulanr. Marka adlar Tubasal, Nemasol Sodyum ve benzeridir. Aminosalisilik asitler, souk algnl, grip veya dier virüs enfeksiyonlarna kar anti-enfektifler dahil olmak üzere farmasötik olarak aktif terkip maddeleridir. Mesalamin (5-aminosalisilik asit, ksaltlm 5-ASA) rektum ve alt kolon iltihab, hafif ila orta ülseratif kolit proktosigmoidit ve proktisit tedavisinde kullanlan, sülfasalazinin aktif bir metaboliti. Para-Aminosalisilik asit (4-hidroksibenzoik asit), gda ve kiisel bakm ürünlerinde koruyucu olarak kullanlan parabenler (p-hidroksi benzoik asitin alkil esterleri) için özel olarak bakteriyostatik maddenin bir arac olarak kullanlr. Sv kristal polimerlerin üretiminde uygulanr. Ayn zamanda boyalar, insektisitler, farmasötikler, pestisitler ve dier kimyasal bileiklerin bir ara maddesi olarak kullanlr. Salisilik Asit ve türevleri, dier farmasötik ürünler, boyalar, aromalar ve koruyucular için önemlidir.