GLYCERYL MONOLAURATE (GLSERL MONOLAURAT)
GLYCERYL MONOLAURATE ( GLSERL MONOLAURAT)
CAS NUMBER: 142-18-7
EC NUMBER: 205-526-6
SYNONYMS:1-MONODODECANOYLGLYCEROL; 1-MONOLAURIN; 2,3-DIHYDROXYPROPYL ESTER DODECANOIC ACID; 2,3-DIHYDROXYPROPYL LAURATE DODECANOIC ACID, 2,3-DIHYDROXYPROPYL ESTER; DODECANOIC ACID, 2,3DIHYDROXYPROPYL ESTER; GLYCERIN 1-MONOLAURATE; GLYCEROL 1-LAURATE; GLYCERYL MONOLAURATE; LAURIC ACID 1-MONOGLYCERIDE; MONOESTER WITH 1,2,3-PROPANETRIOL DODECANOIC ACID;2,3 Dihydroxypropyl dodecanoate; 1-Monolaurin; 142-18-7; Monolaurin; Lauricidin; Glyceryl monolaurate; 1-Monolaurin, Dodecanoic acid-2,3-Dihydorxypropyl ester, 1-Lauroyl-rac-glycerol, 1-Monododecanoyl-rac-glycerol, rac-Glycerol 1-laurate, DL-α-Laurin, Monolaurin, 1-Monolauroyl-rac-glycerol;cithrol GML; (±)-2,3-dihydroxypropyl dodecanoate;2,3-dihydroxypropyl dodecanoate;2,3-dihydroxypropyl laurate;dimodan ML 90;dodecanoic acid 2,3-dihydroxypropyl ester;dodecanoic acid a-monoglyceride;dodecanoic acid, 2,3-dihydroxypropyl ester;1-monododecanoylglycerol;3-dodecanoyloxy-1,2-propanediol;glucerola-monolaurate;glycerin 1-monolaurate;glycerol 1-laurate;rac-glycerol 1-laurate;glycerol 1-monolaurate;monoglycerollaurate; glycerol monolaurate;glyceryl monododecanoate;grindtek ML 90;imwitor 312;lauric acid 1-monoglyceride;lauric acida-monoglyceride;lauric acid monoester with glycerol;lauric acid monoglyceride;lauric acid, monoester with glycerol;lauricidin;1-monolaurin;a-monolaurin;DL-a-Laurin;monolaurin;laurin, 1-mono-laurin, mono-1-lauroyl-rac-glycerol;1-monolauroyl-rac-glycerol; rac-1-lauroylglycerol;monomuls 90L12;monomuls L 90;1-monomyristin;poem M 300, 1 monoxdodecanoyl-rac-glycerol;1-Monolaurin; Glyceryl monolaurate; Lauricidin; L-1475; L1475; L 1475;Laurin,1-mono- (6CI,7CI,8CI);1-Glyceryl laurate;1-Monododecanoylglycerol;1-Monolaurin;1-Monolauroyl-rac-glycerol;3-Dodecanoyloxy-1,2-propanediol;Dodecanoic acid a-monoglyceride;Glycerin 1-monolaurate;Glycerol1-laurate;Glycerol 1-monododecanoate; Glycerol1-monolaurate;Glycerol a-monolaurate;Glyceryl laurate;Glyceryl monododecanoate;Lauric acid 1-monoglyceride;Lauric acid a-monoglyceride;Lauricidin;Luaricidin;NSC 698570;a-Monolaurin;40738-26-9;AI3-03482; Aldo MLD; Aldo MLD-K-FG; Cithrol GML; Dimodan ML 90; EINECS 248-337-4; Glycerin monolaurate; Glycerol monolaurate; Glycerol monolaurate (VAN); Glycerox L 8; Glyceryl monolaurate; Grindtek ML 90; Imwitor 312; Lauric acid monoglyceride; Lauricidin 802; Lauricidin 812; LauricidinR; M 300; Monododecanoyl glycerol; Monoglycerol laurate; Monolaurin; Monolauroylglycerin; Monomuls 90L12; Monomuls L 90; NSC 4837; Poem M 300; Sunsoft 750; Sunsoft 757; Tegin L 90; UNII-Y98611C087; Dodecanoic acid, monoester with 1,2,3-propanetriol; Lauric acid, monoester with glycerol; Laurin, mono- (8CI);;Glyceryl laurate SE;GLYCERYLMONOLAURATE; GLYCETNMONOLAURATE; GLYCERYL MONOLAURATE; GLYCERYN MONOLAURATE; GLSERNMONOLAURAT; GLSERLMONOLAURAT; GLSERL MONOLAURAT; GLSERN MONOLAURAT; glyceylmonolaurate; glycerynmonolaurate; glyceryl monolaurate; glyceryn monolaurate; gliserilmonolaurat; gliserin monolaurat; gliserinmonolaurat, gliseril monolaurat; gliserin mono laurat; gliserin monolaurat; laurat; LAURAT,
Glycerol Monolaurate (GML) is a naturally occurring fatty acid widely utilized in food, cosmetics, and homeopathic supplements. GML is a potent antimicrobial agent that targets a range of bacteria, fungi, and enveloped viruses but select findings suggest that GML also has immunomodulatory functions. In this study, we have mechanistically examined if Gliceryl monolaurate affects the signaling and functional output of human primary T cells. We found that Gliceryl monolaurate potently altered order and disorder dynamics in the plasma membrane that resulted in reduced formation of LAT, PLC-γ, and AKT microclusters. Altered membrane events induced selective inhibition of TCR-induced phosphorylation of regulatory P85 subunit of PI3K and AKT as well as abrogated calcium influx. Ultimately, Gliceryl monolaurate treatment potently reduced TCR-induced production of IL-2, IFN-γ, TNF-α, and IL-10. Our data reveal that the widely used anti-microbial agent GML also alters the lipid dynamics of human T cells, leading to their defective signaling and function.Henan zhengtong chemical co. Ltd offers Glyceryl Monolaurate (GML).
Appearance: Ivory white powder or lamellar solid. It is used as an emulsifier in sanitarian foods and other foods such as bread, cake, streamed bread and moon-cake. It is also used in meat product, dairy product and fruit and vegetable for make the time of preservation longer. Packing: Aluminized bag vacuum packing with nitrogen inside.
Properties:
The biggest advantage of Gliceryl monolaurate is the”not preservatives,but more than preservatives”.Its bacteriostatic effect will not change with the change of PH value suppose PH value is wihtin the scope of 4-8.Its antibacterial spectrum was wide,it has strong interaction in the common bacteria,fungi,yeast in food,and also can inhibit variety of viruses and protozoa. Glyceryl monolaurate also known as lauric acid monoglyceride (Glycerol Monolaurate, called GML). Gliceryl monolaurate is synthesized by direct esterification of lauric acid and glycerin, the general appearance of the scaly or particulate oily, white or light yellow crystal. It is an excellent emulsifier, but also safe and efficient broad-spectrum antimicrobial agents, and the pH is not restricted under neutral or slightly alkaline conditions, there is still a good antibacterial effect.
Application range:
Meat?flavoring?Bean products?flour products?Baked product?filling?Spicy food etc.
Usage:
Dissolve dispersed evenly in the hot water of 70 ~ 80? in advance or edible alcohol,then add in food ingredients, stir well.
Recommended dosage: 0.1~1.0g/kg.
Storage conditions: closed,dry,cool,places.
Gliseril Monolaurat (GML), gda, kozmetik ve homeopatik takviyelerde yaygn olarak kullanlan doal olarak bulunan bir ya asididir. Gliseril Monolaurat , bir dizi bakteri, mantar ve zarfl virüsleri hedef alan güçlü bir antimikrobiyal maddedir, ancak seçilmi bulgular Gliseril Monolaurat ‘nin de immünomodülatör fonksiyonlara sahip olduunu göstermektedir. Bu çalmada, Gliseril monolaurat insan primer T hücrelerinin sinyalleme ve fonksiyonel çktsn etkiliyorsa, mekanik olarak inceledik. Gliseril Monolaurat ‘nin plazma membranndaki düzen ve bozukluk dinamiklerini LAT, PLC-γ ve AKT mikroölçerlerinin azalmasyla sonuçlandn bulduk. Deitirilmi membran olaylar, PI3K ve AKT’nin düzenleyici P85 alt biriminin TCR tarafndan indüklenen fosforilasyonunun seçici olarak inhibe edilmesini ve ayrca giderilmi kalsiyum akn indüklemitir. Son olarak, Gliseril Monolaurat tedavisi, TCR’nin neden olduu IL-2, IFN-y, TNF-a ve IL-10 üretimini azaltmtr. Verilerimiz yaygn olarak kullanlan anti-mikrobiyal ajan Gliseril Monolaurat ‘nin, insan T hücrelerinin lipit dinamiklerini deitirdiini ve bunlarn hatal sinyalizasyona ve ilevlerine yol açtn ortaya çkarmtr. Hoan zhengtong chemical co. Ltd Glyceryl Monolaurate (GML) sunmaktadr.
Görünüm: Fildii
Beyaz toz veya lamellar kat. Sanitarian gdalarda ve ekmek, kek, ak ekmei ve ay-keki gibi dier gda maddelerinde emülgatör olarak kullanlr. Ayn zamanda etin, süt ürününün, meyve ve sebzenin korunma süresini daha uzun yapmak için kullanlr. Paketleme: çinde azot ile alüminize torba vakum paketleme.
Özellikleri:
Gliseril Monolaurat ‘nin en büyük avantaj “koruyucu deil, koruyuculardan daha fazlas” dr. PH deerinin deimesi ile pH deerinin deimesi ile bakteriyostatik etki deimez. PH deeri 4-8’in kapsamdr. Antibakteriyel spektrum geni, güçlüdür. Ortak bakteri, mantar, gdalarda maya etkileimi ve ayrca virüs ve protozoa çeitlerini inhibe edebilir. Gliseril monolaurat ayn zamanda laurik asit monogliserit (GML olarak adlandrlan Gliserol Monolaurat) olarak da bilinir. Gliseril Monolaurat , lorik asit ve gliserinin dorudan esterlenmesiyle, pullu veya partiküllü yal, beyaz veya açk sar kristalin genel görünümü ile sentezlenir. Mükemmel bir emülgatör, ayn zamanda güvenli ve verimli geni spektrumlu antimikrobiyal maddelerdir ve pH nötr veya hafif alkali koullar altnda kstlanmamtr, hala iyi bir antibakteriyel etki vardr.
Uygulama alan:
Et Aromas? Fasulye Ürünleri? Un Ürünleri? Frnda Ürün? Doldurma? Baharatl Gda vb.
Kullanm:
70 ~ 80 scak suda eit olarak dalr? önceden veya yenilebilir alkol, daha sonra gda katk maddeleri ekleyin, iyice kartrn.
Önerilen dozaj: 0.1 ~ 1.0 g / kg.
Depolama koullar: kapal, kuru, serin, yerler.