GLYCOLIC ACID (GLKOLK AST)

GLYCOLIC ACID (GLKOLK AST)

GLYCOLIC ACID (GLKOLK AST)

CAS NO: 79-14-1

METATAGS;2-hydroxyacetic acid; glycolate; glycolic acid; glycolic acid, 1-(14)C-labeled; glycolic acid, 2-(14)C-labeled; glycolic acid, calcium salt; glycolic acid, monoammonium salt; glycolic acid, monolithium salt; glycolic acid, monopotassium salt; glycolic acid, monosodium salt; glycolic acid, potassium salt; hydroxyacetic acid; potassium glycolate; glycolic acid; hydroxyacetic acid; 2-Hydroxyacetic acid; 79-14-1; Hydroxyethanoic acid; Acetic acid, hydroxy-; Glycollic acid; glycolate; Caswell No. 470; Kyselina glykolova; Kyselina glykolova [Czech]; Kyselina hydroxyoctova; glycolicacid; Kyselina hydroxyoctova [Czech]; Glycocide; alpha-Hydroxyacetic acid; POLYGLYCOLIC ACID; EPA Pesticide Chemical Code 000101; GlyPure, GLYCOLLATE
C2H4O3; 2-Hydroxyethanoic acid, Acetic acid, hydroxy-, homopolymer; EINECS 201-180-5; Acetic acid, 2-hydroxy-; .alpha.-Hydroxyacetic acid; Acetic acid, 2-hydroxy-, homopolymer; NSC166; CHEBI:17497; Glycolic acid-13C2; Polyglycollic acid; GOA; Dexon (polyester); 259744-22-4; Poly(L-glycolic acid); Glycolic acid homopolymer; Polyglycolide; Hydroxyacetic acid homopolymer; Hydroxyethanoate; a-Hydroxyacetate; CCRIS 9474; Dicarbonous acid; hydroxy-acetic acid; alpha-Hydroxyacetate; hydroxyl acetic acid; a-Hydroxyacetic acid; Glycolic Acid 70%; 2-hydroxy acetic acid; 2-hydroxy-acetic acid; ACMC-209pgf; omega-Hydroxy fatty acid; 2-hydroxyl ethanoic acid; Glycolic acid, polyesters; GLKOLK AST; GLKOLK ACD; GLICOLIC ASIT; GLIKOLIK ASIT; GLYCOLIC ACID; GLYCOLIC ACIT; GLYCOLIC ASIT.glycolic acid;hydroxyacetic acid;2-Hydroxyacetic acid;79-14-1;Hydroxyethanoic acid;Glycollic acid;Acetic acid, hydroxy-;glycolate;Caswell No. 470;Kyselina glykolova;Kyselina glykolova [Czech];Kyselina hydroxyoctova;glycolicacid;HOCH2COOH;Kyselina hydroxyoctova [Czech];Glycocide;alpha-Hydroxyacetic acid;POLYGLYCOLIC ACID;EPA Pesticide Chemical Code 000101;GlyPure;HSDB 5227;NSC 166;AI3-15362;UNII-0WT12SX38S;GlyPure 70;BRN 1209322;GLYCOLLATE;C2H4O3;2-Hydroxyethanoic acid;Acetic acid, hydroxy-, homopolymer;EINECS 201-180-5;Acetic acid, 2-hydroxy-;.alpha.-Hydroxyacetic acid;Acetic acid, 2-hydroxy-, homopolymer;NSC166;CHEBI:17497;AEMRFAOFKBGASW-UHFFFAOYSA-N;MFCD00004312;Glycolic acid-13C2;Polyglycollic acid;26009-03-0;26124-68-5;GOA;Dexon (polyester);259744-22-4;Poly(L-glycolic acid);Glycolic acid homopolymer;Polyglycolide;Hydroxyacetic acid homopolymer;Hydroxyethanoate;a-Hydroxyacetate;CCRIS 9474;Dicarbonous acid;hydroxy-acetic acid;alpha-Hydroxyacetate;hydroxyl acetic acid;a-Hydroxyacetic acid;Glycolic Acid 70%;2-hydroxy acetic acid;2-hydroxy-acetic acid;ACMC-209pgf;omega-Hydroxy fatty acid;2-hydroxyl ethanoic acid;AC1Q7BOK;AC1Q7BOL;Glycolic acid, polyesters;DSSTox_CID_5363;bmse000245;WLN: QV1Q;AC1L19YH;DSSTox_RID_77763;Glycolic acid (7CI,8CI);GLYCOLIC ACID, CRYST;DSSTox_GSID_25363;ETHYLDIOXY, 2-OXO-;4-03-00-00571 (Beilstein Handbook Reference);KSC377Q2F;ARONIS23902;Glycolic acid, p.a., 98%;0WT12SX38S;Acetic acid, hydroxy- (9CI);CHEMBL252557;DTXSID0025363;CTK2H7822;HMDB00115;NSC-166;MolPort-000-871-981;Glycolic acid solution, 56-58%;Glikolik asit;GLKOLKAST;GLIKOLIKASIT;glikolikasitvegzellik;glycolcacdandbeuty;glikolikaitvesivilcetedavisi;glukoliksit;GLIKOLIKASITVEKREMLER;GLIKOLIKASITKREMLER;SIVILCETEDAVISINDEGLIKOLIKSIT;GLYCOLICACIDBEAUTY;GLKOLKASTNFAYDALARI;GLIKOLIKASITNERDENALINIR;GLIKOLIKASITNEICINKULLANILIR;glikolikasitnerdenalnr;glikolik asit nerden alnr;glikolik asit ne iin kullanlr;glikolik asit ve gzellik;Glycolic acid, >=97.0% (T);STR00936;ZINC4658557;Tox21_301298;ANW-37261;1932-50-9 (mono-potassium salt);39663-84-8 (mono-lithium salt);AKOS000118921;Glycolic acid, ReagentPlus(R), 99%;35249-89-9 (mono-ammonium salt);DB03085;Glycolic acid solution, puriss., 70%;LS-2184;MCULE-9792551388;OR13191;RP18351;RTR-037849;CAS-79-14-1;TRA-0184681;2836-32-0 (mono-hydrochloride salt);NCGC00160612-01;NCGC00160612-02;NCGC00257533-01;AJ-51839;AK128829;AN-23979;K398;KB-77574;OR034123;OR249589;OR249590;OR249802;OR358460;SC-26092;SC-85771;Glycolic acid solution, CP, 70% in H2O;AB1011457;ST2410039;TR-037849;25904-89-6 (unspecified potassium salt);FT-0083160;FT-0612572;G0110;G0196;Glycolic acid, SAJ special grade, >=98.0%;C00160;C03547;Glycolic Acid, pharmaceutical secondary standard;Glycolic acid, Vetec(TM) reagent grade, 98%;M-7418;11046-EP2269610A2;11046-EP2269988A2;11046-EP2270002A1;11046-EP2270003A1;11046-EP2270008A1;11046-EP2270011A1;11046-EP2275401A1;11046-EP2275413A1;11046-EP2277848A1;11046-EP2277867A2;11046-EP2280003A2;11046-EP2281563A1;11046-EP2284160A1;11046-EP2284178A2;11046-EP2284179A2;11046-EP2287156A1;11046-EP2289510A1;11046-EP2289879A1;11046-EP2289890A1;11046-EP2292617A1;11046-EP2295424A1;11046-EP2298735A1;11046-EP2298755A1;11046-EP2301931A1;11046-EP2301937A1;11046-EP2301940A1;11046-EP2305257A1;11046-EP2305646A1;11046-EP2305651A1;11046-EP2308851A1;11046-EP2308854A1;11046-EP2311807A1;11046-EP2311842A2;11046-EP2314588A1;11046-EP2314593A1;11046-EP2316457A1;11046-EP2316458A1;11046-EP2316459A1;11046-EP2316825A1;11046-EP2316826A1;11046-EP2316827A1;11046-EP2316828A1;11046-EP2372017A1;11046-EP2374786A1;11046-EP2374787A1;11046-EP2374895A1;11046-EP2380871A1;47926-EP2301544A1;47926-EP2308851A1;47926-EP2311810A1;49125-EP2272848A1;49125-EP2281824A1;49125-EP2292613A1;49125-EP2295408A1;49125-EP2295426A1;49125-EP2295427A1;49125-EP2295430A2;49125-EP2295431A2;49125-EP2305254A1;49125-EP2305679A1;49125-EP2311823A1;Glycolic acid, BioXtra, >=98.0% (titration);Glycolic acid solution, technical, ~55% in H2O;I04-1094;J-509661;F2191-0224;Glycolic acid solution, high purity, 70 wt. % in H2O;Z1259155884;287EB351-FF9F-4A67-B4B9-D626406C9B13;Glycolic acid solution, technical grade, 70 wt. % in H2O;Glycolic acid, certified reference material, TraceCERT(R);InChI=1/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5;Glycolic acid, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%;ALPHA/BETA HYDROXY ACIDS (GLYCOLIC ACID) (SEE ALSO ALPHA/BETA HYDROXY ACIDS);1033720-45-4;1033720-48-7;702627-33-6;GLICOLIC ACID;GLIKOLIK ACID;GLICOLICACID;GLICOLIKACID;GLICOLIC ASIT;GLIKOLIC ASIT;GLIKOLIKASIT;GLKOLK AST;GLCOLC AST;GLCOLC ACD;Glicolic acid;Glicolic asit;Glikolik asit;Glikolik ast;glukolik asit;glukolc acd;Glukolik asit;Glucolic acid;Glukolikasit;Glukolicacd;glikolik asit;glcolc acd;glicolic acid;glycolic asit;glikolik asit;Glikolik Asit;gulukolik asit;gulukolik acd ;GULUKOLK AST; GLUKOLK ACD;gulukoliksit;gulukolkacd;GULUKOLIKASIT;GULUKOLIKACID

EC Number: 201-180-5

Names and Identifiers of Glycolc Acd
Computed Descriptors of Glycolc Acd
IUPAC Name of Glycolc Acd
2-hydroxyacetic acid

Molecular Formula of Glycolc Acd
C2H4O3

Chemical and Physical Properties of Glycolc Acd

Property Name
Molecular Weight:76.051 g/mol
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Complexity:40.2
Topological Polar Surface Area:57.5 A^2
Monoisotopic Mass:76.016 g/mol
Exact Mass:76.016 g/mol
XLogP3:-1.1
Compound Is Canonicalized:true
Formal Charge:0
Heavy Atom Count:5
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Isotope Atom Count:0
Covalently-Bonded Unit Count:1

Physical Description of Glycolc Acd

Liquid

Color of Glycolc Acd
Colorless, translucent solid

Odor of Glycolc Acd
Odorless

Boiling Point of Glycolc Acd
100 deg C

Melting Point of Glycolc Acd
79.5 C

Glycolic acid (hydroacetic acid or hydroxyacetic acid); chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest ?-hydroxy acid (AHA). This colorless, odorless, and hygroscopic crystalline solid is highly soluble in water. It is used in various skin-care products. Glycolic acid is found in some sugar-crops. A glycolate or glycollate is a salt or ester of glycolic acid.

The name “glycolic acid” was coined in 1848 by the French chemist Auguste Laurent (1807-1853). He proposed that the amino acid glycine – which was then called glycocolle – might be the amine of a hypothetical acid, which he called “glycolic acid” (acide glycolique). When the team of Strecker and Sokolov finally produced glycolic acid in 1851, they bestowed, on their acid, the name of Laurent`s hypothetical acid.

Uses of Glycolc Acd

Glycolic acid is used in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent. It is also used in adhesives and plastics. Glycolic acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss. It is used in surface treatment products that increase the coefficient of friction on tile flooring.

Due to its excellent capability to penetrate skin, glycolic acid finds applications in skin care products, most often as a chemical peel performed by a dermatologist in concentrations of 20 to 70% or at-home kits in lower concentrations between 10 and 20%. In addition to concentration, pH also plays a large part in determining the potency of glycolic acid in solution. Physician-strength peels can have a pH as low as 0.6 (strong enough to completely keratolyze the epidermis), while acidities for home peels can be as high as 2.5. Glycolic acid is used to improve the skin`s appearance and texture. It may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis.[citation needed] Once applied, glycolic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together. This allows the stratum corneum to be exfoliated, exposing live skin cells. Highly purified grades of glycolic acid are commercially available for personal care applications.

Glycolic acid is also a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization. It is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA). From the commercial perspective, important derivatives include the methyl (CAS# 96-35-5) and ethyl (CAS# 623-50-7) esters which are readily distillable (b.p. 147-9 and 158-159 C, respectively), unlike the parent acid. The butyl ester (b.p. 178-186 C) is a component of some varnishes, being desirable because it is nonvolatile and has good dissolving properties.

Glycolic acid is an exfoliator.
Glycolic acid products comes in many different forms: cleansers, serums, moisturizers, eye creams and facial peels.

Glycolic acid is a member of alpha hydroxyacids (AHA), naturally occurring in different fruits and also known as fruit acids. Glycolic acid is found in sugar cane in nature.

EC Numaras: 201-180-5

Glikolik Acd isimleri ve tanmlayclar
Glikolik Acd`n Hesaplanan Tanmlayclar
IUPAC Glikolik Acd ismi
2-hidroksiasetik asit

Glikolik Acd`n Molekler Forml
C2H4O3

Glikolik Acd`n kimyasal ve fiziksel zellikleri

zellik ad
Molekler Arlk: 76.051 g / mol
Hidrojen Bam Balayc Says: 2
Hidrojen Ba Alc Says: 3
Dnebilen Bond Says: 1
Karmaklk: 40.2
Topolojik Polar Yzey Alan: 57.5 A ^ 2
Monoizotopic Ktle: 76.016 g / mol
Tam Ktle: 76.016 g / mol
XLogP3: -1.1
Bileik Canonicalized: true
Resmi arj: 0
Ar Atom Says: 5
Tanml Atom Stereocenter Says: 0
Tanmsz Atom Stereocenter Says: 0
Tanmlanm Bond Stereocenter Says: 0
Tanmlanmam Bond Stereocenter Says: 0
zotop Atom Says: 0
Kovalent Bal Birim Says: 1

Glikolik Acd`n Fiziksel Tanm

Sv

Glikolik Acd`n Rengi
Renksiz, yar effaf kat madde

Glikolik Acd Kokusu
Kokusuz

Glikolik Acd Kaynama Noktas
100 derece C

Glikolik Asidin Erime Noktas
79.5 C

Glisolik asit (hidroasetik asit veya hidroksiasetik asit); C2H4O3 (ayrca HOCH2CO2H olarak yazlr) kimyasal forml, en kk ?-hidroksi asittir (AHA). Bu renksiz, kokusuz ve higroskopik kristal kat suda yksek znrle sahiptir. eitli cilt bakm rnlerinde kullanlr. Glikolik asit baz eker mahsullerinde bulunur. Bir glikolat veya glikolat, glikolik asidin bir tuzu veya esteridir.

“Glikolik asit” ad 1848 ylnda Fransz kimyager Auguste Laurent (1807-1853) tarafndan retildi. O, daha sonra glikolleol denilen – amino asit glisinin, “glikolik asit” (asit glikolik) olarak adlandrd varsaymsal bir asitin amini olabileceini nermiti. Strecker ve Sokolov ekibi nihayet 1851`de glikolik asit rettiklerinde, Laurent`in varsaymsal asitinin adn asitlerine verdiler.

Glikolik asitin Kullanm Alanlar
Glikolik asit tekstil endstrisinde boyama ve tabaklama maddesi olarak, lezzet verici bir ajan olarak ve koruyucu olarak gda ilemede ve ila endstrisinde cilt bakm maddesi olarak kullanlr. Yapkanlarda ve plastiklerde de kullanlr. Glikolik asit genellikle ak zelliklerini iyiletirmek ve parlaklk kazandrmak iin emlsiyon polimerleri, solventler ve mrekkep ve boya katk maddeleri iine katlr. Karo deme zerindeki srtnme katsaysn arttran yzey ileme rnlerinde kullanlr.

Glikolik asit cilde nfuz etme zelliinden dolay, cilt bakm rnlerinde, ounlukla% 20 ila 70 konsantrasyonlarda bir dermatolog tarafndan yaplan kimyasal soyma veya% 10 ila% 20 arasnda daha dk konsantrasyonlarda evde kullanlan kiti bulur. Konsantrasyona ek olarak, pH da zeltideki glikolik asitin potansiyelini belirlemede byk bir rol oynamaktadr. Hekim mukavemetli kabuklarn pH deeri 0.6`ya kadar debilir (evde tamamen keratolizlemek iin yeterince gldr), ancak evde kabuk soyma asitleri 2.5 kadar yksek olabilir. Glikolik asit, cildin grnmn ve dokusunu iyiletirmek iin kullanlr. Krklklar, akne skarn, hiperpigmentasyonunu azaltabilir ve aktinik keratozis, hiperkeratozis ve seboreik keratoz gibi birok cilt rahatszln iyiletirebilir. Glikolik asit, uygulandktan sonra, epidermisin st tabakasyla reaksiyona girerek, balanma zelliklerini zayflatabilir. l cilt hcrelerini bir arada tutan lipidler. Bu, stratum corneum`un pul pul dklmesine ve canl cilt hcrelerinin ortaya kmasna izin verir. Yksek oranda saflatrlm glikolik asit dereceleri, kiisel bakm uygulamalar iin piyasada bulunmaktadr.

Glikolik asit, oksidasyon-redksiyon, esterifikasyon ve uzun zincirli polimerizasyon da dahil olmak zere bir dizi reaksiyonda organik sentez iin de yararl bir ara maddedir. Poliglikolik asit ve dier biyolojik olarak uyumlu kopolimerlerin (r. PLGA) hazrlanmasnda bir monomer olarak kullanlr. Ticari adan, nemli trevler, kolaylkla damtlabilen metil (CAS # 96-35-5) ve etil (CAS # 623-50-7) esterlerini (srasyla bp 147-9 ve 158-159 C) Ana asidin aksine. Butil ester (b.p. 178-186 C) baz verniklerden biridir, artlm olmas nedeniyle, uucu deildir ve iyi zlme zelliklerine sahiptir.

Glisol asidi bir eksfoliyatrdr.
Glikolik asit rnleri birok farkl formda bulunur: temizleyiciler, serumlar, nemlendiriciler, gz kremleri ve yz kabuklar.
Glikolik asit deiik meyvelerde doal olarak bulunan ve meyve asitleri olarak da bilinen alfa hidroksiasitlerin (AHA) bir yesidir. Glikolik asit, doada eker kamnda bulunur.