GLYOXAL 40

Table of Contents

GLYOXAL 40

Glyoxal 40 (Glioksal 40)

 

CAS No: 107-22-2

EC No: 203-474-9

 

 

synonyms:

Glioksal 40; Glioksal 40%; Ethanedial; 107-22-2; GLOKSAL 40; GLOKSAL 40%; Oxalaldehyde; oxaldehyde; 1,2-Ethanedione; Glyoxylaldehyde;Diformyl; Biformal; Biformyl; Diformal; Aerotex glyoxal 40; Glyoxal aldehyde; Ethanedial, trimer; Ethanediol, trimer; Glyoxal, 40%; Glyoxal solution; Glyoxal solutions; CCRIS 952; UNII-50NP6JJ975; Ethane-1,2-dione; C2H2O2; HSDB 497; Glyoxal, 29.2%; EINECS 203-474-9; Glyoxal, 40% in water; BRN 1732463; AI3-24108; CHEBI:34779; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; Ethane-1,2-dione; C2H2O2; HSDB 497; Glyoxal, 29.2%; EINECS 203-474-9; Glyoxal, 40% in water; BRN 1732463; AI3-24108; CHEBI:34779; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; MFCD00006957; NCGC00091228-01; DSSTox_CID_5364; DSSTox_RID_77764; DSSTox_GSID_25364; 40094-65-3; Ethanedione; CAS-107-22-2; Glyoxal solution, ~40% in H2O (~8.8 M); bisformyl; oxypolygelatine; Gelifundol; Oxypolygelatin; Ethandial; Glycoxal; Glyfosfin; ethane dial; (oxo)acetaldehyde; ethane-1,2-dial; Protectol GL 40; ODIX; NSC 262684; AC1L1PPU; ACMC-1BV6U; Glyoxal, 40 % Solution; Glyoxal solution, 40.0%; 4-01-00-03625 (Beilstein Handbook Reference); BIDD:ER0284; (CHO)2; AC1Q28J9; Glyoxal, Biformyl, Oxalaldehyde; CHEMBL1606435; DTXSID5025364; CTK0H4953; Glyoxal, 40% w/w aq. soln.; MolPort-001-780-154; 50NP6JJ975; BB_SC-7204; ZINC8437750; Tox21_111105; Tox21_202517; NW-43524; BBL011519; LS-36; NSC262684; STL146635; AKOS000119169; Glyoxal solution, 40 wt. % in H2O; MCULE-3212938778; NSC-262684; RP18241; RTR-001406; TRA0067179; KS-00000V42; GLYOXAL, 76%, POWDER (TRIMER); NCGC00260066-01; AN-22473; KB-52297; OR034237; OR369233; SC-19118; Glyoxal solution, CP, 40 wt. % in H2O; TR-001406; FT-0626792; G0152; X8004; Glioxaldehit; etandial, 1,2-Etandiol; Diformil; Etandione; Glioxal aldehit; C14448; Glyoxal solution, 40 wt. % in water 100ml; 57421-EP2269977A2; 57421-EP2270006A1; 57421-EP2289896A1; 57421-EP2308878A2; 57421-EP2377845A1; Gelatins, reaction products with glyoxal, oxidized; J-001740; S14-1487; F2191-0152; Glyoxal solution, ~40% in H2O, for HPLC derivatization; Glyoxal solution, BioReagent, for molecular biology, ~40% in H2O (~8.8 M); 83513-30-8; 9005-91-8; Ethanedial; Ethanedione; Glyoxal; 40094-65-3; 1162; 262684; MD2700000; 2810; 50NP6JJ975; Oxaldehyde; InChI=1S/C2H2O2/c3-1-2-4/h1-2H; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; C(=O)C=O; OHCCHO; 1,2-Ethanedione; Diformal; ethandial; Ethanedial; Ethanedione; MFCD00006957; Oxalaldehyd; Oxalaldehyde; GXT; ODIX; oxal; Protectol GL 40; trans-glyoxal; UNII:50NP6JJ975; EDO; Gelifundol; gliksol; glioksal; gilioksal; gilioxal; glioxal; glyoksal; glyoxale; glioksale; glyoxal; ODIX; Oxal; (CHO)2; GLYOXA; GLYOXAL; DIFORMYL; Biformal; Biformyl; Diformal; GLYOXALE; CB1280241; InChIKeyLEQAOMBKQFMDFZ-UHFFFAOYSA-N; NIST Chemistry Reference; Ethanedial(107-22-2); Glyoxal; (Ethanedione, 1, 2-) (107-22-2); AEROTEX GLYOXAL 40; BIFORMAL; BIFORMYL; DAICEL GY 60; DIFORMAL; DIFORMYL; ETHANDIAL; ETHANEDIAL; ETHANEDIOL; ETHANEDIONE; 1,2-ETHANEDIONE; GLYFIX CS 50; GLYOXAL; GLYOXAL ALDEHYDE; GLYOXAL, 40% SOLUTION; GLYOXYLALDEHYDE; GOHSEZAL P; OXAL; OXALALDEHYDE; OXALDEHYDE; PERMAFRESH 114; MFCD00006957; Biformyl; Ethanedial; 1,2-Ethanedione; Oxalaldehyde; Ethanedial; Biformal; Biformyl; Diformyl; Ethanedione; Glyoxal aldehyde; Glyoxylaldehyde; Oxal; Oxalaldehyde; 1,2-Ethanedione; (CHO)2; Diformal; Ethane-1,2-dione; Ethandial; Aerotex glyoxal 40; ODIX; Protectol GL 40; LEQAOMBKQFMDFZ-UHFFFAOYSA-N; GLYOXAL; 1,2-ETHANEDIONE; ETHANEDIAL; DIFORMYL;Glioksal 40 ; BIFORMYL; OXALDEHYDE; Ethanedial; oxalaldehyde; Glyoxal, 40 % Solution; 83513-30-8; 50NP6JJ975; 1732463; MFCD00006957; 58.03634000; diformal; ethandial; ethane dial; ethane-1,2-dial; ethanedial; ethanedione; 1,2-ethanedione; gelifundol; glyoxal aldehyde; glyoxylaldehyde; oxalaldehyde; oxaldehyde; Glyoxaldehyde; Ethanedial; 1,2-Ethanedione; Diformyl; Ethanedione; Glyoxal aldehyde; 1,2-Ethanedione; Biformyl; Ethanedial; Oxalaldehyde; C2H2O2 / OHCCHO; Molecular mass: 58.0; ICSC # 1162; Glyoxal, 40 wt% solution in water; AC156220000; AC156220010, AC156220025; AC156220050; AC156225000; BP1370-500; Biformal; Diformal; Ethandial; Glyoxylaldehyde; 231-791-2; 203-474-9; 7732-18-5; ZC0110000; 107-22-2;MD2625000; MD2650000; MD2700000; 7-(2-Hydroxyethyl)decahydro-1H,6H-3a,5a,8a,10a-tetraazapyrene; 1435472-42-6 ; Ethanedial; oxalaldehyd; Glyoxal 40dehyde, Ethanedial, 1,2-Ethanedione, Diformyl, Ethanedione, Glyoxal aldehyde; Ethane-1,2-dione; Biformal; Ethanedial; Oxalaldéhyde; Glyoxal 40; Glyoxal 40%; Glyoxal %40; Glioksal 40; Glioksal 40%; Glioksal %40; GLYOXAL 40; GLYOXAL 40%; GLYOXAL %40; GLOKSAL 40; GLOKSAL 40%; GLOKSAL %40; GLIOKSAL 40; GLIOKSAL 40%; GLIOKSAL %40;

 

 

 

 

Glyoxal 40

Glyoxal 40

 

 

Glyoxal 40

Skeletal formula of Glyoxal 40

Space-filling model of glyox

Names

Preferred IUPAC name

Oxaldehyde

Systematic IUPAC name

Ethanedial

Other names of Glyoxal 40 40 

Glyoxal 40

Oxalaldehyde

Identifiers of Glyoxal 40 

CAS Number of Glyoxal 40 

107-22-2 ☑

3D model (JSmol)

Interactive image

ChEBI 

CHEBI:34779 ☑

ChemSpider 

7572 ☑

ECHA InfoCard 100.003.160

KEGG 

C14448 ☑

PubChem CID

7860

UNII 

50NP6JJ975 ☑

Properties of Glyoxal 40 

Chemical formula of Glyoxal 40 

C2H2O2

Molar mass of Glyoxal 40 58.036 g·mol-1

Density of Glyoxal 40 1.27 g/cm3

Melting point of Glyoxal 40 15 °C (59 °F; 288 K)

Boiling point of Glyoxal 40 51 °C (124 °F; 324 K)

Thermochemistry

Heat capacity of Glyoxal 40 (C)

1.044 J/(K·g)

Hazards

NFPA 704 (fire diamond) 

NFPA 704 four-colored diamond

121

Flash point -4 °C (25 °F; 269 K)

Autoignition

temperature

285 °C (545 °F; 558 K)

Related compounds

Related aldehydes

acetaldehyde

glycolaldehyde

propanedial

methylglyoxal

Related compounds

glyoxylic acid

glycolic acid

oxalic acid

pyruvic acid

diacetyl

acetylacetone

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

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Infobox references

Glyoxal 40 is an organic compound with the chemical formula OCHCHO. It is the smallest dialdehyde (a compound with two aldehyde groups). It is a crystalline solid, white at low temperatures and yellow near the melting point (15 °C). The liquid is yellow, and the vapor is green.[1]

 

Pure Glyoxal 40 is not commonly encountered because it forms hydrates, which oligomerize. For many purposes, these hydrated oligomers behave equivalently to Glyoxal 40. Glyoxal 40 is produced industrially as a precursor to many products.[2]

Glyoxal 40% Applications

1.Glyoxal mainly used for glyoxylate, M2D resin, imidazole and other raw materials, products, and as gelatin, gelatin, cheese, alcohol, and insoluble starch adhesives, artificial silk resistance reduction agent.

2.Recently , With the fast development of the application in pharmacy, textiles and daily construction materials, the application of glyoxal can be wider and wider..

3.In medicine, mainly for the special ring imidazole drugs such as metronidazole, dimetridazole, imidazole, etc..

4.In the intermediate area, mainly for glyoxylate, D-hydroxyphenylglycine, allantoin, benzene Enzyme pharynx, berberine;

5.In the textile, the main agent used for finishing clothing, 2D resin, M2D resin;

6.In the paper industry, mainly for sizing, wet strength increased resistance of paper;in polymer chemistry is a very ef fective cross-linking Factor for cross-linking agent;

7.In the construction industry, cement curing agent used to improve the solidification strength, as a contro

 

Glyoxal 40% Storage

Keep container tightly closed in a dry and well-ventilated place.

Recommended storage temperature: 2 – 8 °C

 

 

External links

Production

Glyoxal 40 was first prepared and named by the German-British chemist Heinrich Debus (1824-1915) by reacting ethanol with nitric acid.[3][4]

 

Commercial Glyoxal 40 is prepared either by the gas-phase oxidation of ethylene glycol in the presence of a silver or copper catalyst (the Laporte process) or by the liquid-phase oxidation of acetaldehyde with nitric acid.[2]

The first commercial Glyoxal 40 source was in Lamotte, France, started in 1960. The single largest commercial source is BASF in Ludwigshafen, Germany, at around 60,000 tons per year. Other production sites exist also in the US and China. Commercial bulk Glyoxal 40 is made and reported as a 40%-strength solution in water.

Glyoxal 40 may be synthesized in the laboratory by oxidation of acetaldehyde with selenious acid.[5]

Anhydrous Glyoxal 40 is prepared by heating solid Glyoxal 40 hydrate(s) with phosphorus pentoxide and condensing the vapors in a cold trap.[6]

 

Applications of Glyoxal 40 40 

Coated paper and textile finishes use large amounts of Glyoxal 40 as a crosslinker for starch-based formulations. It condenses with urea to afford 4,5-dihydroxy-2-imidazolidinone, which further reacts with formaldehyde to give the bis(hydroxymethyl) derivative dimethylol ethylene urea, which is used for wrinkle-resistant chemical treatments of clothing, i.e. permanent press.

 

Glyoxal 40 is used as a solubilizer and cross-linking agent in polymer chemistry.

Glyoxal 40 is a valuable building block in organic synthesis, especially in the synthesis of heterocycles such as imidazoles.[8] A convenient form of the reagent for use in the laboratory is its bis(hemiacetal) with ethylene glycol, 1,4-dioxane-2,3-diol. This compound is commercially available.

Glyoxal 40 solutions can also be used as a fixative for histology, that is, a method of preserving cells for examining them under a microscope.

Glyoxal 40 and its derivatives are also used in the chemical probing of RNA structure, as they react with free guanines in RNAs.[9]

Speciation in solution

 

Hydrated Glyoxal 40 (top) and derived oligomers, called dimers and trimers. The middle and lower species exist as mixtures of isomers.

Glyoxal 40 is supplied typically as a 40% aqueous solution.[2] Like other small aldehydes, Glyoxal 40 forms hydrates. Furthermore, the hydrates condense to give a series of oligomers, some of which remain of uncertain structure. For most applications, the exact nature of the species in solution is inconsequential. At least one hydrate of Glyoxal 40 is sold commercially, Glyoxal 40 trimer dihydrate: [(CHO)2]3(H2O)2 (CAS 4405-13-4). Other Glyoxal 40 equivalents are available, such as the ethylene glycol hemiacetal 1,4-dioxane-trans-2,3-diol (CAS 4845-50-5, m.p. 91-95 °C),

 

Glyoxal 40 is estimated that, at concentrations less than 1 M, Glyoxal 40 exists predominantly as the monomer or hydrates thereof, i.e., OCHCHO, OCHCH(OH)2, or (HO)2CHCH(OH)2. At concentrations above 1 M, dimers predominate. These dimers are probably dioxolanes, with the formula [(HO)CH]2O2CHCHO.[10] Dimer and trimers precipitate as solids from cold solutions.

 

Other occurrences

Glyoxal 40 has been observed as a trace gas in the atmosphere, e.g. as an oxidation product of hydrocarbons.[11] Tropospheric concentrations of 0-200 ppt by volume have been reported, in polluted regions up to 1 ppb by volume.

 

 

Molecular Weight of Glyoxal 40 58.04

Molecular Formula of Glyoxal40 C2H2O2

Storage RT

Catalogue No GXL999

CAS No. of Glyoxal 40 107-22-2

Backward-integrated production process of Glyoxal 40

Ethylene – Ethylene glycol – Glyoxal 40%

-Textile resins

-Paper resins

-Oilfield

-Imidazoles

 

 

Sustainability of Glyoxal 40 :

Glyoxal 40 is readily biodegradable by

showing more than 90% decrease of

dissolved organic carbon according to

OECD guidelines 301 C-E and 303 A.

Accreditation for food packaging:

Glyoxal 40 is listed as an accredited

chemical substance for the production

of paper for food packaging by the

Federal Institute for Risk Assessment

(BfR) in Germany, and by the Food

and Drug Administration (FDA) in the

U.S.

Substitution of aldehydes:

Glyoxal 40 shows high potential in the

substitution of aldehydes, e.g. for

formaldehyde or glutaraldehyde. Additionally, in disinfection it can be used

as a co-biocide formulated together

with glutaraldehyde.

Reliability:

With 60,000 metric tons annual worldscale production in Ludwigshafen

we are a leading player in the Glyoxal 40

industry. Our backward-integrated

production of Glyoxal 40 guarantees

efficient and reliable supply wherever

you are.

Services:

Whether you need bulk or packaged

material, we ensure efficient solutions.

Our advice on packaging and dedicated

storage facilities guarantee reliable

supply to allow you to run your business

steadily.

Application expertise:

we make our expertise available to our partners. Working together

with our customers in successful

partnerships will offer mutual benefits.

Registration support:

 

 

Description

General description

The product is 40wt.% solution of Glyoxal 40 in water. Glyoxal 40 is a linear aliphatic dialdehyde containing two aldehyde groups.[1] Glyoxal 40 participates in the synthesis of glyoxylic acid. It is highly reactive in nature. Glyoxal 40can be prepared by oxidizing ethanol or acetaldehyde with nitric acid.Glyoxal 40 is widely employed in textile and paper industry.[2]

 

 

Application

Glyoxal 40 solution has been used as a crosslinking agent during the synthesis of DNA-containing nanoparticles in a study.[3] Glyoxal 40 has been used as derivatizing reagent, in the precolumn fluorescence derivatization of N-terminal tryptophan containing peptides which can be separated via high performance liquid chromatography.[4] Glyoxal 40 may also be used in the synthesis of Glyoxal 40 bis(4-phenyl-3-thiosemicarbazones)solution, which can be used in the spectrophotometric determination of palladium in catalysts.[5]

 

 

Packaging

1, 3 kg in poly bottle

 

5 g in glass bottle

100 g in poly bottle

22, 50 kg in poly drum

 

Other Notes

This form of glyoxal 40 is composed of 3 moles of Glyoxal 40 and 2 moles of water in a relatively stable configuration.

 

 

Caution

May precipitate on storage; redissolve at 50-60 °C.

Glyoxal 40 , 40 % Solution is used to denature nucleic acids by forming stable complexes with guanine residues

Glyoxal 40%

Categories: Fluid

Material Notes: Formula: C2H2O2

CAS: 107-22-2

 

Description: Glyoxal 40 is a colorless to yellow liquid, with a faint odor. Glyoxal 40 is also miscible with water.

Synonyms: Glyoxaldehyde, Ethanedial, 1,2-Ethanedione, Diformyl, Ethanedione, Glyoxal aldehyde

Applications: Intermediate used in the production of Adhesives, Cross linkers, Paper resins, Pharmaceuticals, Sulfur scavenging and Textile resins

Product Description:Glyoxal 40, 40% solution: Glyoxal 40 is a nucleic acid denaturant. It acts as a specific probe for homopurine strands of DNA.

GENERAL DESCRIPTION

Yellow crystals melting at15°C. Hence often encountered as a light yellow liquid with a weak sour odor. Glyoxal 40 is a 2-carbon aldehyde with carbonyl groups on both carbons.Glyoxal 40 is a yellow crystals melting at15°C. Hence often encountered as a light yellow liquid with a weak sour odor. Vapor has a green color and burns with a violet flame.

Combustible. Incompatible with strong oxidizing agents. Strong reducingagent. May polyermize exothermically. Incompatible with air, water, oxygen,peroxides, amides, amines, hydroxy-containing material s, nitric acid, aldehydes. Corrodes many metals.

 

Mechanism of Action

 

Glyoxal 40 attacks the amino groups of proteins, nucleotides, and lipids with its highly reactive carbonyl groups. A sequence of non-enzymatic reactions, called glycation, yields stable advanced glycation end-products (AGEs) with a background extent of 0.1-1% of lysine and arginine residues in proteins and 1 in 1.0 X 10-7 nucleotides in DNA. … Glyoxal 40 forms stable adducts with guanosine by reaction with the N-1 as well as with the exocyclic nitrogen of guanine. The rate of Glyoxal 40-guanine adduct formation is rapid under physiological conditions. A stable tricyclic Glyoxal 40-DNA adduct is formed by covalent binding to two nitrogens of guanine under physiological conditions in vitro. Besides 8-hydroxy-deoxyguanosine, the Glyoxal 40-deoxyguanosine (dG) adduct is one of the major deoxyguanosine oxidation products, being formed by oxygen radicals, lipid peroxidation systems, various types of oxidative stress, and UV irradiation and after in vivo exposure to beta-hydroxy-substituted N-nitrosamines.

Glyoxal 40 (O=CH-CH=O) is an α-oxoaldehyde, and it is often grouped with two similar α-oxoaldehydes, methylGlyoxal 40, and 3-deoxyglucosone. All three compounds are products of various metabolic and oxidative reactions and are capable of causing cellular damage and apoptosis. They are also involved in the formation of advanced glycation end-products (AGEs) which have been linked to long-term sequela of chronic diseases such as diabetic retinopathy, neuropathy, and nephropathy. Glyoxal 40 is primarily detoxified by the Glyoxal 40ase system present in the cells of bacteria, protozoa, fungi, plants, animals, and humans. However, it has been suggested that several other enzymes are capable of detoxifying Glyoxal 40, including aldehyde dehydrogenase (ALDH) which can oxidize Glyoxal 40 to glyoxylate.

Glyoxal 40 is considered an important intermediate in the formation of advanced glycation end-products (AGEs). AGE modification alters protein function and inactivates enzymes, resulting in disturbance of cellular metabolism, impaired proteolysis, and inhibition of cell proliferation and protein synthesis. The extent of AGE modification increases with the increasing life span of proteins. Consequently, AGEs are especially associated with long-lived proteins, such as collagens, lens crystallins, and neurofilaments, but also have been identified in shorter-lived proteins, including hemoglobin, plasma proteins, lipoproteins, and intracellular proteins.

Inhibition studies in bacterial mutagenicity tests demonstrated the production of the reactive oxygen species superoxide, hydrogen peroxide, and singlet oxygen from Glyoxal 40. The mutagenic activity of Glyoxal 40 is related to singlet oxygen, as well as to the intracellular GSH level. The hydroxyl radical plays a prominent role in Glyoxal 40-induced DNA cleavage.

Isolated rat hepatocytes were incubated with different concentrations of Glyoxal 40. Glyoxal 40 by itself was cytotoxic at 5mM, depleted GSH, formed reactive oxygen species (ROS) and collapsed the mitochondrial membrane potential. Glyoxal 40 also induced lipid peroxidation and formaldehyde formation. Glycolytic substrates, eg fructose, sorbitol and xylitol inhibited Glyoxal 40-induced cytotoxicity and prevented the decrease in mitochondrial membrane potential suggesting that mitochondrial toxicity contributed to the cytotoxic mechanism. Glyoxal 40 cytotoxicity was prevented by the Glyoxal 40 traps d-penicillamine or aminoguanidine or ROS scavengers were also cytoprotective even when added some time after Glyoxal 40 suggesting that oxidative stress contributed to the Glyoxal 40 cytotoxic mechanism.

The cytosolic GSH-dependent Glyoxal 40ase system is the major pathway for the detoxification of Glyoxal 40 … Glyoxal 40 reacts non-enzymatically with GSH with formation of a hemithioacetal, which is subsequently converted to S-glycolylglutathione by Glyoxal 40ase I. Glyoxal 40ase II catalyses the hydrolysis of S-glycolylglutathione to glycolate, re-forming the GSH from the first reaction. The activity of Glyoxal 40ase I in situ is approximately proportional to the cytosolic concentration of GSH. When GSH is severely depleted (eg, under conditions of oxidative stress), however, 2-oxoaldehyde dehydrogenase and aldose reductase may also metabolize Glyoxal 40. Imbalances in intracellular redox systems may impair these detoxification mechanisms, resulting in higher levels of Glyoxal 40. A further GSH-independent route of detoxification via Glyoxal 40ase III exists.

 

Use and Manufacturing

 

 

Fillers

Intermediates

Odor agents

Processing aids, not otherwise listed

Solids separation agents

Water Treatment Products

 

Its versatile properties the intermediate Glyoxal 40 is the product of choice for various applications. In textile manufacturing, for example, this efficient crosslinker decreases water uptake in crosslinking cellulose. In oil recovery, Glyoxal 40 crosslinks polymers, thus increasing the viscosity of fracturing fluids.

Glyoxal 40 is also used in the paper, leather and epoxy industries. Beside known applications, Glyoxal 40 shows potential for new applications which are still in the early stages of development.

 

 

Glioksal 40

 

 

Glioksal 40

Glioksal 40 iskelet formülü

Glioksal 40 boluk doldurma modeli

simler

Tercih edilen IUPAC ad

Oxaldehyde

Sistematik IUPAC ad

etandial

Dier isimler

Glioksal 40

Oxalaldehyde

Glioksal 40 Tanmlayclar

Glioksal 40 CAS numaras

107-22-2 ☑

3D model ( JSmol )

Etkileimli görüntü

Chebi 

Glioksal 40 Chebi: 34779 ☑

Glioksal 40 ChemSpider 

7572 ☑

Glioksal 40 ECHA Bilgi Kart 100.003.160

Glioksal 40 KEGG 

C14448 ☑

Glioksal 40 PubChem CID

7860

Glioksal 40 UNII 

50NP6JJ975 ☑

Glioksal 40 CompTox Kontrol Paneli ( EPA )

DTXSID5025364 Bunu Wikidata’da düzenle

InChI[göster]

SMILES[göster]

Glioksal 40 Özellikleri

Glioksal 40 Kimyasal formül

C- 2 , H 2 O 2

Glioksal 40 Molar kütle 58.036 g · mol -1

Glioksal 40 Younluk 1.27 g / cc 3.

Glioksal 40 Erime noktas 15 ° C (288 K)

Glioksal 40 Kaynama noktas 51 ° C (124 ° F; 324 K)

Glioksal 40 Termokimya

Glioksal 40 Is kapasitesi ( C )

1.044 J / (K · g)

Glioksal 40 Tehlikeler

NFPA 704 (ate prlanta) 

NFPA 704 dört renkli elmas

121

Glioksal 40 Alevlenme noktas -4 ° C (25 ° F; 269 K)

Kendiliinden tutuma

scakl

285 ° C (545 ° F; 558 K)

Bantl bileikler

lgili aldehitler

asetaldehit

glikolaldehid

propanedial

metilGlioksal 40

Bantl bileikler

glikoksilik asit

glikolik asit

oksalik asit

piruvik asit

diasetil

asetilaseton

Aksi belirtilmedikçe, standart halindeki malzemeler için veriler verilir (25 ° C [77 ° F], 100 kPa’da).

☑ dorula ( nedir ?) ☑☒

Bilgi kutusu referanslar

Glioksal 40 bir bir organik bileik ile kimyasal formül OCHCHO. En küçük dialdehittir (iki aldehit grubuna sahip bir bileik ). Glioksal 40 Kristalli bir katdr, düük scaklklarda beyazdr ve erime noktasna (15 ° C) yakn sardr .Glioksal 40 Sv sar ve buhar yeildir. [1]

 

Saf Glioksal 40 yaygn olarak görülmez, çünkü oligomerize olan hidratlar oluturur . Birçok amaç için, bu hidratlanm oligomerler, Glioksal 40 ile ayn ekilde davranrlar. Endüstriyel olarak birçok ürünün öncüsü olarak üretilir. [2]

 

üretim

Glioksal 40 ilk önce etanolü nitrik asit ile reaksiyona sokarak Alman-ngiliz kimyager Heinrich Debus (1824-1915) tarafndan hazrland ve adlandrld . [3] [4]

 

Ticari Glioksal 40 gaz faz yoluyla hazrlanr oksidasyon ve etilen glikol , bir mevcudiyetinde gümü ya da bakr katalizörü (Laporte ilemi) ya da sv fazl oksidasyonu ile asetaldehid ile nitrik asit . [2]

lk ticari Glioksal 40 kaynak oldu Lamotte tek büyük ticari kaynadr 1960 ylnda balayan, aralarnda Fransa BASF içinde Ludwigshafen , Almanya ylda yaklak 60.000 ton. ABD ve Çin’de baka üretim tesisleri de bulunmaktadr. Ticari dökme Glioksal 40 yaplr ve suda% 40’lk bir mukavemet çözeltisi olarak rapor edilir.

Glioksal 40 , asetaldehitin selenious asit ile oksidasyonu yoluyla laboratuvarda sentezlenebilir . [5]

Susuz Glioksal 40 , kat Glioksal 40 hidrat (lar) fosfor pentoksit ile starak ve buharlar souk bir tuzakta younlatrarak hazrlanr . [6]

 

Glioksal 40 Uygulamalar 

Glioksal 40 Kue kat ve tekstil kaplamalar , 

Glioksal 40 niasta bazl formülasyonlar için çapraz balayc olarak büyük miktarlarda kullanr .

Glioksal 40 Üre ile younlaarak , giysinin krmaya dayankl kimyasal ilemleri, yani kalc pres için kullanlan bis (hidroksimetil) türevi dimetilol etilen üre verecek ekilde formaldehit ile reaksiyona giren 4,5-dihidroksi-2-imidazolidinon elde edilir.

 

Glioksal 40 , polimer kimyasnda bir çözünürletirici ve çapraz balama maddesi olarak Glioksal 40 kullanlr .

Glioksal 40 organik sentezde , özellikle imidazoller gibi heterosikllerin sentezinde deerli bir yap tadr . [8] Laboratuarda kullanm için uygun bir reaktif formu etilen glikol , 1,4-dioksan-2,3-diol ile bis (hemiasetal) ‘dir . Bu bileik ticari olarak temin edilebilir.

Glioksal 40 çözeltiler ayrca histoloji için bir fiksatif olarak , yani hücreleri mikroskop altnda incelemek için bir koruma yöntemi olarak kullanlabilir.

Glioksal 40 ve türevleri, RNA’lardaki serbest guaninlerle reaksiyona girdikleri için RNA yapsnn kimyasal olarak incelenmesinde de kullanlr . [9]

Çözeltide türleme

 

Hidratl Glioksal 40 (üstte) ve dimerler ve trimerler olarak adlandrlan türetilmi oligomerler. Orta ve alt türler izomer karmlar olarak bulunur.

Glioksal 40 tipik olarak% 40’lk bir sulu çözelti halinde salanr. [2] Dier küçük aldehitler gibi ,Glioksal 40 da hidratlar oluturur. Ayrca hidratlar, bazlar belirsiz bir yapda kalan bir dizi oligomer vermek üzere younlar. Çou uygulama için, çözeltideki türlerin kesin doas önemsizdir. Glioksal 40 en az bir hidrat, ticari olarak satlmaktadr, Glioksal 40 trimeri dihidrat: [(CHO) 2 ] 3 (H 2 O) 2 (CAS 4405-13-4). Etilen glikol hemiasetal 1,4-dioksan- trans -2,3-diol ( CAS 4845-50-5, en 91-95 ° C) gibi dier Glioksal 40 edeerleri mevcuttur ,

 

1 M’den düük konsantrasyonlarda , Glioksal 40n arlkl olarak monomer veya hidratlar, yani OCHCHO, OCHCH (OH) 2 veya (HO) 2 CHCH (OH) 2 olduu tahmin edilmektedir . 1 M’nin üzerindeki konsantrasyonlarda dimerler baskndr. Bu dimerler muhtemelen dioksolanlar , formül [(HO) CH] ile, 2 O 2 CHCHO. [10] Dimer ve trimerler souk çözeltilerden katlar halinde çökelir.

 

Dier olaylar 

Glioksal 40 atmosferde bir eser gaz olarak, örnein hidrokarbonlarn bir oksidasyon ürünü olarak gözlenmitir . [11] Hacimce 1 ppb’ye kadar kirli bölgelerde, hacimce 0-200 ppt troposferik konsantrasyonlar bildirilmitir. [12]

 

 

Glioksal 40 Ürün açklamas

Glioksal 40% hzl ayrntlar

Kimyasal ad: Glioksal 40% mix

Glioksal 40 CAS No.: 107-22-2

Glioksal 40 EINECS .:203-474-9

Glioksal 40 Moleküler formülü: C2H2O2

Glioksal 40 Kimyasal yaps:Günlük kullanm kimyasallar için glioksal 40%

Glioksal 40 Formülü arlk: 58.04

Glioksal 40 Tahlil: 40% min

Dier isimler: bisformil; glioksilaldehit; Glioksal 40 çözelti;

Glioksal 40; diformil; etanedial; 1,2-etanedion; oksalaldehit

Örnek: mevcut ve ücretsiz.

Uygulamalar özet: tekstil, kat, deri, kozmetik

 

Glioksal 40% Uygulamalar

1. Glioksal 40 arlkl olarak glioksilat, M2D reçine, imidazol ve dier hammaddeler, ürünler ve jelatin, jelatin, peynir, alkol ve çözünmez niasta yaptrclar, yapay ipek direnci azaltma maddesi olarak kullanlr.

2. Son zamanlarda, eczane, tekstil ve günlük inaat malzemelerinde uygulamann hzl geliimi ile, Glioksal 40 uygulamas daha geni ve daha geni olabilir ..

3. Tpta, özellikle metronidazol, dimetridazole, imidazol vb. Gibi özel halka imidazol ilaçlar için Glioksal 40 kullanlr.

4. Ara alanda, esas olarak glioksilat, d-hidroksifenil glisin, allantoin, benzen enzim farenks, berberin için;

5. Tekstilde, giysiler, 2D reçine, M2D reçine için Glioksal 40 kullanlan ana maddedir;

6.Glioksal 40 Kat endüstrisinde, özellikle boyutlandrma için, slak mukavemet kat direncini arttrr; polimer kimyada çapraz balama maddesi için çok ef fektif çapraz balama faktörüdür;

7. Glioksal 40 Inaat sektöründe, bir contro olarak katlama gücünü artrmak için kullanlan çimento kürleme maddesi

Glioksal 40% Depolama

Kab kuru ve iyi havalandrlm bir yerde skca kapal tutun.

Önerilen depolama scakl: 2-8 °C

GENEL TANIM

Glioksal 40 15 ° C`de eriyen sar kristallerdir. Bu nedenle Glioksal 40 sklkla zayf bir eki kokuya sahip açk sar bir sv olarak karlalr. Glioksal 40, Buharn yeil bir rengi vardr ve mor bir alevle yanar. Glioksal 40, Yancdr.Glioksal 40 Güçlü oksitleyici ajanlarla uyumaz. Glioksal 40, Güçlü indirgeyicidir. Glioksal 40 Egzotermik olarak polimerize olabilir. Glioksal 40 Hava, su, oksijen, peroksitler, amidler, aminler, hidroksi içeren maddeler, nitrik asit, aldehitlerle uyumaz. Glioksal 40, Birçok metali korozif hale getirir.

 

HAREKET MEKANZMASI

 

Glioksal 40, proteinleri, nükleotidleri ve lipidlerin amino gruplarna yüksek oranda reaktif karbonil gruplaryla saldrr. Glikasyon denilen enzimatik olmayan reaksiyonlardan oluan bir dizi, DNA`da linyin ve arginin artklarn ve DNA`da 1.0 x 10-7 nükleotidde 1`lik bir arka plan kapsam ile kararl ilerlemi glikasyon son ürünler (AGE`ler) üretir. … Glyoksal, Guanin`in ekzosiklik azotunun yan sra N-1 ile reaksiyona girerek guanozin ile kararl adüktler oluturur. Glioksal-guanin adükt oluumu fizyolojik koullar altnda hzldr. Stabil bir trisiklik glioksal-DNA adüktü, in vitro fizyolojik koullar altnda iki guanin azotuna kovalent balanma yoluyla oluur. 8-hidroksi-deoksiguanozin yan sra, glioksal-deoksiguanozin (dG) adükt, oksijen radikalleri, lipit peroksidasyon sistemleri, çeitli oksidatif stres tipleri ve UV nlamas ile ve in vivo beta maruziyetinden sonra olumakta olan önemli deoksiguanozin oksidasyon ürünlerinden biridir -hidroksi-ikameli N-nitrosaminler.

Glioksal 40, gelimi glikasyon son ürünler (AGE`ler) oluumunda önemli bir ara ürün olarak düünülür. AGE modifikasyonu protein fonksiyonunu deitirir ve enzimleri inaktive eder, bu da hücresel metabolizma bozukluuna, bozulmu proteolize ve hücre proliferasyonunun ve protein sentezinin inhibisyonuna neden olur. AGE modifikasyonunun derecesi, proteinlerin ömrünün uzamasna bal olarak artmaktadr. Sonuç olarak, AGE`ler özellikle kollajen, mercek kristalinleri ve nörofilamentler gibi uzun ömürlü proteinlerle ilikilidir ancak ayn zamanda hemoglobin, plazma proteinleri, lipoproteinler ve hücre içi proteinler de dahil olmak üzere daha ksa süren proteinlerde tanmlanmtr.

 

Bakteriyel mutajenite testlerinde yaplan inhibisyon çalmalar, glioksaldan süperoksit, hidrojen peroksit ve singlet oksijen üretildiini göstermitir. Glioksaln mutajenik aktivitesi, singlet oksijene ve hücre içi GSH seviyesine ilikindir. Hidroksil radikali glioksal kaynakl DNA bölünmesinde belirgin bir rol oynamaktadr.

 

zole edilmi sçan hepatositleri farkl glkoksal konsantrasyonlar ile inkübe edildi. Glioksal 40 tek bana 5 mM`de sitotoksik, tükenmi GSH, reaktif oksijen türleri (ROS) oluturdu ve mitokondriyal membran potansiyelini çökertti. Glyoksal ayn zamanda lipit peroksidasyonu ve formaldehit oluumuna neden olmutur. Glikolitik substratlar, örnein fruktoz, sorbitol ve ksilitol glioksal kaynakl sitotoksisiteyi inhibe etti ve mitokondriyal membran potansiyelindeki azalmay önledi, mitokondriyal toksisitenin sitotoksik mekanizmaya katkda bulunduunu düündürdü. Glioksal sitotoksisite, glioksal tuzaklar d-penisilamin veya aminoguanidin ile engellendi veya ROS atclar, glioksal sonras bir süre ilave edildiklerinde bile sitoprotektifti; oksidatif stresin glioksal sitotoksik mekanizmaya katkda bulunduunu düündürdü.

Sitozolik GSH`ye bal glioksalaz sistemi, glioksaln detoksifikasyonunun balca yoludur. Glioksal 40, gliokzalaz I ile daha sonra S-glikolglutatiyona dönütürülen bir hemitiyoasetal oluumu ile enzimatik olmayan ekilde GSH ile tepkimeye girer. Glikozalaz II, hidrolizini katalize eder S-glikolglutatyonun glikolata dönütürülmesi, ilk reaksiyondan GSH`nin yeniden oluturulmas. Gloksalaz I in in situ aktivitesi, GSH`nin sitozolik konsantrasyonu ile yaklak olarak orantldr. GSH iddetle tükendiinde (örnein, oksidatif stres koullar altnda), 2-oksoaldehid dehidrojenaz ve aldoz redüktaz da glioksal metabolize edebilir. Hücre içi redoks sistemindeki dengesizlikler bu detoksifikasyon mekanizmalarn bozabilir ve bu da glioksal düzeyinin yükselmesine neden olabilir. Glyokzalaz III yoluyla GSH`den bamsz bir baka detoksifikasyon yolu mevcuttur.

 

KULLANIM VE MALAT

 

 

Dolgu

Ara ürünler

Koku maddeleri

leme yardmclar

Kat ayrma maddeleri

Su Artma Ürünleri

 

Çok yönlü özellikleri ara Glioksal 40, çeitli uygulamalar için tercih edilen üründür. Örnein, tekstil imalatnda, bu verimli çapraz balayc, çapraz balayc selülozdaki su alm miktarn düürür. Glioksal 40 Ya geri kazanmnda, glioksal, polimerleri çapraz balar ve böylece krk akkanlarn viskozitesini arttrr.

Glioksal 40 kat, deri ve epoksi endüstrilerinde de kullanlr. Bilinen uygulamalarn yannda, glioksal, geliimin erken evrelerinde olan yeni uygulamalar için potansiyel göstermektedir. laçlarn, yaptrclar ve kaplayclarn, tekstil reçinelerinin ve tekstil reaktan ürünlerin üretiminde, kat reçinelerinin üretiminde ve of set-özel kaplama banyolarnda kullanlr. Çapraz balayclarn üretiminde ara madde olarak kullanlr. Örnein; kopolimerlerin üretimi, boya ara maddeleri, ilaçlar, mahsül (ürün) koruma ajanlar, böcek ilaçlar, kat, tekstil ve deri yardmclar, korozyon önleyiciler ve fotoraf kimyasallar için kullanlr. Organik sentezlerde (tbbi ürünler, boya maddeleri vs…), ev ve hastane dezenfeksiyonu biositlerinde, çeitli muhteliflerin kullanm, çeitli doldurucularn ynlanmas ve mineral doldurucu muamelesinde, selüloz eterlerinin yumrulama kart ilenmesinde ve hava koku giderici ajanlarda kullanlr. Ayrca hidrokolloidlerin üretimi, epoksi ve fenolik reçinelerin üretiminde ve tütün katks olarak da kullanlmaktadr.

 

 

 

Glyoxal 40 

Glyoxal 40 en solution aqueuse pour la synthèse

Formule: C₂H₂O₂

Poids moléculaire: 58,04 g/mol

Densité: 1,27 g/cm³ (20 °C)

Température de stockage: Température ambiante

Numéro MDL: MFCD00006957

Numéro CAS: 107-22-2

EINECS: 203-474-9

UN: 0000

 

 

Éthanedial

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Éthanedial

Glyoxal-2D-skeletal.svg Glyoxal 40-3D-vdW.png

Identification

Nom UICPA éthanedial

Synonymes 

éthane-1,2-dione, glyoxal

 

 

No CAS 107-22-2

No ECHA 100.003.160

SMILES 

[Afficher]

InChI 

[Afficher]

Apparence liquide, prisme jaune sous 15 °C

Propriétés chimiques

Formule brute C2H2O2 [Isomères]

Masse molaire1 58,0361 ± 0,0023 g/mol

C 41,39 %, H 3,47 %, O 55,14 %,

Propriétés physiques

T° fusion 15 °C2

T° ébullition 50,4 °C2,3

Solubilité 600 g·l-1 dans l’eau à 20 °C2

Masse volumique 1,14 g·cm-32

Pression de vapeur saturante 293 mbar à 20 °C 2

Unités du SI et CNTP, sauf indication contraire.

modifier Consultez la documentation du modèle

L’éthanedial ou Glyoxal 40 est un composé organique de formule brute C2H2O2 et de formule semi-développé O=CH-CH=O. Ce liquide de couleur jaune est le plus petit dialdéhyde existant. C’est aussi une forme tautomère de l’éthynediol (HO-C≡C-OH) .

 

 

Sommaire

1 Production et synthèse

2 Utilisation

3 Solution d’éthanedial

4 Autre origine

5 Références

6 Lien externe

Production et synthèse

L’éthanedial commercial est préparé soit par l’oxydation en phase gazeuse de l’éthylène glycol (éthane-1,2-diol), catalysée par de l’argent voire du cuivre, soit par l’oxydation en phase liquide d’éthanal en présence d’acide nitrique. La capacité globale de production est d’environ 220 000 tonnes par an avec une baisse de production due à une surcapacité asiatique. La plupart de la production se fait en phase gazeuse. Le premier producteur d’éthanedial était situé sur le site de Lamotte à Trosly-Breuil en France, site dont le propriétaire actuel est Weylchem. Aujourd’hui la production est largement dominée par BASF en Allemagne, sur le site de Ludwigshafen. Ils atteignent 60 000 tonnes par an. Il existe seulement deux sites de production en Amérique (Geismer en Californie et Charlotte en Caroline du nord). Récemment, la Chine s’est dotée de capacités de production supplémentaires.

 

Au laboratoire, l’éthanedial est synthétisé par oxydation de l’éthanal avec de l’acide sélénique4. La préparation de l’éthanedial anhydre se fait par chauffage d’hydrates de ce composé avec du pentoxyde de phosphore dans un dispositif doté d’un recondenseur5.

 

Utilisation

Les industries du papier et du textile utilisent de grandes quantités d’éthanedial qui joue le rôle d’agent de réticulation pour des formulations à partir d’amidon. C’est également un initiateur des urées utilisées lors de traitements chimiques augmentant la résistance aux froissements. L’éthanedial sert d’agent de solubilisation et d’agent de réticulation en chimie des polymères:

 

 

protéines (tannage du cuir)

collagène

dérivés cellulosiques (textiles)

hydrocolloides

amidon

c’est un bon intermédiaire en chimie organique, particulièrement pour la synthèse d’hétérocycles comme les imidazoles6. Une forme du réactif utilisée en laboratoire est le bis-hemiacétal avec de l’éthylène glycol, 1,4-dioxane-2,3-diol. Ce composé est disponible dans le commerce.

 

 

Solution d’éthanedial

Le composé est fourni typiquement en solution aqueuse concentrée à 40 %. Comme d’autres petits aldéhydes, il forme des hydrates. De plus ces hydrates se condensent pour former une série d’oligomères, dont la structure reste mal connue. Pour la plupart des applications, la structure exacte n’a pas de conséquences. Au moins deux hydrates d’éthanedial sont vendus dans le commerce:

 

 

un dimère d’éthanedial, dihydraté: [(CHO)2]2[H2O]2, 1,4-dioxane-trans-2,3-diol (CAS# 4845-50-5, p.f. 91 à 95 °C)

un trimère d’éthanedial, dihydraté:: [(CHO)2]3(H2O)2 (CAS# 4405-13-4).

On estime qu’à des concentrations inférieures à 1 mol/L, l’éthanedial existe majoritairement sous forme de monomère, c’est-à-dire: OCHCHO, OCHCH(OH)2, ou (HO)2CHCH(OH)2. À des concentrations supérieures à 1 mol/L, la forme prédominante est le dimère. Ces dimères sont probablement des dioxanes, de formules [(HO)CH]2O2CHCHO7. Les dimères et les trimères peuvent précipiter en raison d’une solubilité plus faible dans des solutions plus froides, à moins de 4,4 °C.

 

 

Autre origine

L’éthanedial est un composé inflammable formé lorsqu’on chauffe des mélanges d’huiles et de lipides à haute température.

 

 

Information Technique

 

 

Formulation :40% w/w aq. soln

État Physique :Liquid

Solubilité :Soluble in water (1000 mg/ml), DMSO, and methanol.

STOCKAGE :Store at 4° C

Point de fusion :-14° C

Point d’Ébullition :104° C

Densité :1.27 g/mL at 20° C

Indice de Réfraction :n20D 1.41

 

 

Description de Glyoxal 40%:

Glyoxal 40%

 

Solution d’eau glyoxal 40%

Glyoxal 40 est l’aldéhyde doux le plus simple, la formule moléculaire est OHCCHO et le poids moléculaire est 58, le monomère Glyoxal 40 pur est achromatique ou jaune clair ou liquide, avec une proportion (d20 ° C) 1,26, points de fusion 15 ° C, point d’ébullition 50,5 ° C et indice de réfraction 1,3826. La vapeur de Glyoxal 40 est verte, en brûlant, elle envoie une flamme pourpre. Le Glyoxal 40 industriel peut se dissoudre dans l’eau, l’éther et l’ethaol. Le Glyoxal 40 industriel existe habituellement dans une solution aqueuse d’environ 40% d’eau. Outre la nature réactionnelle de tout l’aldéhyde, le Glyoxal 40 a une propriété chimique spéciale pour ses deux groupes fonctionnels de coordonnées.

La réaction de la solution aqueuse de Glyoxal 40 est identique à celle du Glyoxal 40 moléculaire unique. Les réactions majoritaires sont des réactions de substitution auxquelles se produisent deux atomes d’hydroxyle. Le Glyoxal 40 réagit avec le composé au centre du nucléophile individuel, et produit des molécules de type ligne. Le Glyoxal 40 réagit avec le composé au centre des deux nucléophiles stables et entraîne des réactions de cyclocompounds, mais prépare de nombreux produits chimiques fins, la médecine et les intermédiaires de la médecine.

Application

1. Glyoxal 40 principalement utilisé pour le glyoxylate, la résine M2D, l’imidazole et d’autres matières premières, des produits, et comme la gélatine, la gélatine, le fromage, l’alcool et les adhésifs d’amidon insoluble, agent de réduction de la résistance artificielle de soie.

2. Récemment, avec le développement rapide de l’application en pharmacie, les textiles et les matériaux de construction quotidiens, l’application de Glyoxal 40 peut être plus large et plus large.

3. En médecine, principalement pour les médicaments anidazole en anneau spéciaux tels que le métronidazole, le dimetridazole, l’imidazole, etc.

4. dans la zone intermédiaire, principalement pour le glyoxylate, la D-hydroxyphénylglycine, l’allantoïne, le benzène, l’Enzyme pharynx, la berbérine;

5. Dans le textile, le principal agent utilisé pour la finition des vêtements, résine 2D, M2D résine;

6. Dans l’industrie papetière, principalement pour le calibrage, la résistance à l’état humide augmente la résistance du papier, dans la chimie des polymères est un facteur de réticulation très ef fi cace pour l’agent de réticulation;

 

7. dans l’industrie de la construction, l’agent de durcissement de ciment utilisé pour améliorer la force de solidification, comme un glissement de terrain de contrôle, peut empêcher la perte de boue pour empêcher l’effondrement.

Glyoxal 40 40

 

Solution permettant de déterminer les réductones dans le vin.

La détermination du SO2 libre ne tient pas compte des réductones dans les vins. Les réductones sont des substances auxquelles le sulfite se lie, comme les polyphénols (principalement le tanin), l’acétaldéhyde et l’acide ascorbique (vitamine C). En moyenne, on table respectivement sur 5 mg/l, 10 mg/l et 30 mg/l de réductones dans le vin, pour les vins blancs, rosés et rouges. On calcule ensuite le SO2 libre (mg/l) en retranchant du SO2 mesuré 5, 10 ou 30 mg/l de réductones. Attention, il s’agit d’une quantité estimée.

Pour déterminer la quantité réelle, l’utilisation du Glyoxal 40 est nécessaire. Ce produit permet de se faire une idée plus précise de la quantité de réductones dans le vin, exprimée en mg/l.

 

EXPOSITION, EFFETS SUR LA SANTE

Voies d’exposition

La substance peut être absorbée dans l’organisme par inhalation de ses aérosols ou de vapeurs et par ingestion.

 

 

Effets liés à une exposition de courte durée

La substance est irritante pour les yeux et la peau.

 

 

Risque inhalatoire

Une contamination dangereuse de l’air peut être atteinte très rapidement par évaporation de cette substance à 20 °C .

 

 

Effets liés à une exposition prolongée ou répétée

Le contact répété ou prolongé peut provoquer une sensibilisation cutanée. 

Utilisations

Propriétés physiques

Nom Substance Détails

Glyoxal 40 anhydre

Formule C H O

N° CAS 107-22-2

Etat Physique Liquide

Masse molaire 58,04

Point de fusion 15 °C

Point d’ébullition 50,4 °C (avec dégagement de vapeurs verdâtres, odeur âcre)

Densité 1,14

Densité gaz / vapeur 2

Pression de vapeur 29 kPa à 20 °C

Point d’éclair –

Température d’auto-inflammation –

Glyoxal 40 en solution aqueuse

0 40 % en poids

Formule

N° CAS

Etat Physique Liquide

Masse molaire –

Point de fusion – 14 °C

Point d’ébullition 104 °C

Densité 1,27

Densité gaz / vapeur –

Pression de vapeur 2,4 kPa à 20 °C

Point d’éclair > 100 °C

Température d’auto-inflammation 285 °C

Propriétés chimiques

[1, 2]

Agent de réticulation dans l’industrie du papier, des peintures, colles et adhésifs.

Intermédiaire de synthèse pour la fabrication de produits pharmaceutiques, parfums, colorants, agents de réticulation pour l’industrie textile et divers produits

chimiques.

Désodorisant dans les industries pétrolière et gazière.

Biocide : Le Glyoxal 40 est utilisé comme substance active en tant que produit biocide dans les catégories désinfectants (type de produits (TP) 2 à 4) selon le règlement

528/212/UE.

Une évaluation du Glyoxal 40 est en cours au niveau européen pour les seuls usages cités ci-dessus (France rapporteur). L’utilisation de ces produits biocides est

soumise aux obligations prévues pendant cette période transitoire (cf. partie « Réglementation »).

[1 à 4]

Le Glyoxal 40 anhydre

Il se présente sous la forme d’un liquide jaune pâle ou de cristaux prismatiques, plus ou moins réguliers, jaunes, devenant blancs au refroidissement. La forme

anhydre n’est pas utilisée dans l’industrie.

Très hygroscopique, il se transforme rapidement sous l’action de l’humidité en hydrate de Glyoxal 40 (ou tétrahydroxyéthane), puis en oligomères de celui-ci.

Il est très soluble dans l’eau (600 g/L) ; la dissolution du Glyoxal 40 anhydre s’accompagne d’une polymérisation rapide et exothermique ; cette réaction peut être

violente. Il est également soluble dans de nombreux solvants organiques anhydres.

Le Glyoxal 40 en solution aqueuse

Dans l’industrie, le Glyoxal 40 est essentiellement livré et utilisé sous forme de solutions aqueuses (la plupart du temps à 40 % en poids). Ces solutions, incolores ou jaune

pâle, d’odeur aigre légère, ont un caractère acide (pH = environ 2) et les propriétés suivantes (pour une solution à 40 % en poids).

Le Glyoxal 40 à l’état solide

Le Glyoxal 40 est parfois commercialisé sous forme de cristaux de dihydrate (tétrahydroxyéthane et oligomères), très hygroscopiques, solubles dans l’eau.

 

 

Le Glyoxal 40 est un composé très réactif. Il peut réagir violemment avec les oxydants, les acides et les bases fortes. Le contact du produit anhydre avec l’eau entraîne

une polymérisation rapide et exothermique.

En solution aqueuse, le Glyoxal 40 hydraté forme divers oligomères dont l’équilibre dépend du pH, de la température et de la concentration. Dans les conditions

normales d’emploi, les solutions aqueuses sont stables.

Les solutions ont un caractère corrosif vis-à-vis de certains métaux : acier ordinaire, cuivre, aluminium.

Le stockage du Glyoxal 40 et de ses solutions peut s’effectuer dans des récipients en acier inoxydable ou en matières plastiques (polyester et polymères fluorés tels que

polytétrafluoroéthylène).

Le verre est également utilisable pour de petites quantités : dans ce cas, les bonbonnes seront protégées par une enveloppe métallique plus résistante,

convenablement ajustée

 

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