KOSTERAN-S/3 G
KOSTERAN-S/3 G
CAS No. : 26658-19-5
EC No. : 247-891-4
Synonyms:
KOSTERAN-S/3 G; Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; Anhydrosorbitol tristearate; Sorbitan tristearate; Sorbitan, trioctadecanoate; Sorbitan tristearate [USAN:INN:BAN]; EC 247-891-4; EINECS 247-891-4; Sorbitan tristearate; Sorbitan tristearate. (Compound usually contains also associated fatty acids); Sorbitani tristearas; Sorbitani tristearas [INN-Latin]; Span 65; Triestearato de sorbitano; Triestearato de sorbitano [INN-Spanish]; Tristearate de sorbitan; Tristearate de sorbitan [INN-French]; UNII-6LUM696811; Sorbitan tristearate; Sorbitan, esters, trioctadecanoate; Sorbitan, trioctadecanoate; 6LUM696811; 1338-42-7; 1629056-13-8; 184594-25-0; 7281-30-3; 86595-70-2; 0026658195; KOSTERAN S3G; COSTERAN S3G; COSTERAN-S3 G; KOSTERAN S3 G; COSTERAN S3 G; Sorbitan Tristearat; SORBITAN TRISTEARAT; SORBTON TRSTEARAT; KOSTERAN-S/3 G; Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; Anhydrosorbitol tristearate; Sorbitan tristearate; Sorbitan, trioctadecanoate; Sorbitan tristearate [USAN:INN:BAN]; EC 247-891-4; EINECS 247-891-4; Sorbitan tristearate; Sorbitan tristearate. (Compound usually contains also associated fatty acids); Sorbitani tristearas; Sorbitani tristearas [INN-Latin]; Span 65; Triestearato de sorbitano; Triestearato de sorbitano [INN-Spanish]; Tristearate de sorbitan; Tristearate de sorbitan [INN-French]; UNII-6LUM696811; Sorbitan tristearate; Sorbitan, esters, trioctadecanoate; Sorbitan, trioctadecanoate; 6LUM696811; 1338-42-7; 1629056-13-8; 184594-25-0; 7281-30-3; 86595-70-2; 0026658195; KOSTERAN S3G; COSTERAN S3G; COSTERAN-S3 G; KOSTERAN S3 G; COSTERAN S3 G; Sorbitan Tristearat; SORBITAN TRISTEARAT; SORBTON TRSTEARAT; KOSTERAN-S/3 G; Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; Anhydrosorbitol tristearate; Sorbitan tristearate; Sorbitan, trioctadecanoate; Sorbitan tristearate [USAN:INN:BAN]; EC 247-891-4; EINECS 247-891-4; Sorbitan tristearate; Sorbitan tristearate. (Compound usually contains also associated fatty acids); Sorbitani tristearas; Sorbitani tristearas [INN-Latin]; Span 65; Triestearato de sorbitano; Triestearato de sorbitano [INN-Spanish]; Tristearate de sorbitan; Tristearate de sorbitan [INN-French]; UNII-6LUM696811; Sorbitan tristearate; Sorbitan, esters, trioctadecanoate; Sorbitan, trioctadecanoate; 6LUM696811; 1338-42-7; 1629056-13-8; 184594-25-0; 7281-30-3; 86595-70-2; 0026658195; KOSTERAN S3G; COSTERAN S3G; COSTERAN-S3 G; KOSTERAN S3 G; COSTERAN S3 G; Sorbitan Tristearat; SORBITAN TRISTEARAT; SORBTON TRSTEARAT; KOSTERAN-S/3 G; Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; Anhydrosorbitol tristearate; Sorbitan tristearate; Sorbitan, trioctadecanoate; Sorbitan tristearate [USAN:INN:BAN]; EC 247-891-4; EINECS 247-891-4; Sorbitan tristearate; Sorbitan tristearate. (Compound usually contains also associated fatty acids); Sorbitani tristearas; Sorbitani tristearas [INN-Latin]; Span 65; Triestearato de sorbitano; Triestearato de sorbitano [INN-Spanish]; Tristearate de sorbitan; Tristearate de sorbitan [INN-French]; UNII-6LUM696811; Sorbitan tristearate; Sorbitan, esters, trioctadecanoate; Sorbitan, trioctadecanoate; 6LUM696811; 1338-42-7; 1629056-13-8; 184594-25-0; 7281-30-3; 86595-70-2; 0026658195; KOSTERAN S3G; COSTERAN S3G; COSTERAN-S3 G; KOSTERAN S3 G; COSTERAN S3 G; Sorbitan Tristearat; SORBITAN TRISTEARAT; SORBTON TRSTEARAT; KOSTERAN-S/3 G; Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; Anhydrosorbitol tristearate; Sorbitan tristearate; Sorbitan, trioctadecanoate; Sorbitan tristearate [USAN:INN:BAN]; EC 247-891-4; EINECS 247-891-4; Sorbitan tristearate; Sorbitan tristearate. (Compound usually contains also associated fatty acids); Sorbitani tristearas; Sorbitani tristearas [INN-Latin]; Span 65; Triestearato de sorbitano; Triestearato de sorbitano [INN-Spanish]; Tristearate de sorbitan; Tristearate de sorbitan [INN-French]; UNII-6LUM696811; Sorbitan tristearate; Sorbitan, esters, trioctadecanoate; Sorbitan, trioctadecanoate; 6LUM696811; 1338-42-7; 1629056-13-8; 184594-25-0; 7281-30-3; 86595-70-2; 0026658195; KOSTERAN S3G; COSTERAN S3G; COSTERAN-S3 G; KOSTERAN S3 G; COSTERAN S3 G; Sorbitan Tristearat; SORBITAN TRISTEARAT; SORBTON TRSTEARAT; KOSTERAN-S/3 G; Span 65; Sorbitan, trioctadecanoate; Anhydrosorbitol tristearate; Sorbitan, esters, trioctadecanoate; Sorbester P38; Sorbitan tristearate, BAN, USAN; Sorbitan tristearate [USAN:BAN:INN]; E492; Anhydrosorbitol tristearate; Sorbitan tristearate; Sorbitan, trioctadecanoate; Sorbitan tristearate [USAN:INN:BAN]; EC 247-891-4; EINECS 247-891-4; Sorbitan tristearate; Sorbitan tristearate. (Compound usually contains also associated fatty acids); Sorbitani tristearas; Sorbitani tristearas [INN-Latin]; Span 65; Triestearato de sorbitano; Triestearato de sorbitano [INN-Spanish]; Tristearate de sorbitan; Tristearate de sorbitan [INN-French]; UNII-6LUM696811; Sorbitan tristearate; Sorbitan, esters, trioctadecanoate; Sorbitan, trioctadecanoate; 6LUM696811; 1338-42-7; 1629056-13-8; 184594-25-0; 7281-30-3; 86595-70-2; 0026658195; KOSTERAN S3G; COSTERAN S3G; COSTERAN-S3 G; KOSTERAN S3 G; COSTERAN S3 G; Sorbitan Tristearat; SORBITAN TRISTEARAT; SORBTON TRSTEARAT;
EN
KOSTERAN-S/3 G IUPAC Name [2-(4-hydroxy-3-octadecanoyloxyoxolan-2-yl)-2-octadecanoyloxyethyl] octadecanoate
KOSTERAN-S/3 G InChI=1S/C60H114O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h54-55,59-61H,4-53H2,1-3H3
KOSTERAN-S/3 G InChI Key IJCWFDPJFXGQBN-UHFFFAOYSA-N
KOSTERAN-S/3 G Canonical SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(C1C(C(CO1)O)OC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC
KOSTERAN-S/3 G Molecular Formula C60H114O8
KOSTERAN-S/3 G CAS 26658-19-5
KOSTERAN-S/3 G EC Number 247-891-4
KOSTERAN-S/3 G E number E492 (thickeners, …)
KOSTERAN-S/3 G Molar mass 963.54 g/mol
KOSTERAN-S/3 G Appearance Waxy solid
KOSTERAN-S/3 G Physical Description Liquid; OtherSolid
KOSTERAN-S/3 G Form Hard, waxy solid
KOSTERAN-S/3 G Colour Light cream to Tan
KOSTERAN-S/3 G Acid Value Max 7 mgKOH/gm
KOSTERAN-S/3 G Saponification Value 176-188 mgKOH/gm
KOSTERAN-S/3 G Moisture content Max 1%
KOSTERAN-S/3 G Hydroxyl Value 66-80 mgKOH/gm
KOSTERAN-S/3 G Heavy Metals (as Pb) Less than 10mg/kg
KOSTERAN-S/3 G Arsenic Less than 3 mg/kg
KOSTERAN-S/3 G Cadmium Less than 1mg/kg
KOSTERAN-S/3 G Mercury Less than 1 mg/kg
KOSTERAN-S/3 G Molecular Weight 963.5 g/mol
KOSTERAN-S/3 G XLogP3-AA 24.3
KOSTERAN-S/3 G Hydrogen Bond Donor Count 1
KOSTERAN-S/3 G Hydrogen Bond Acceptor Count 8
KOSTERAN-S/3 G Rotatable Bond Count 56
KOSTERAN-S/3 G Exact Mass 962.851371 g/mol
KOSTERAN-S/3 G Monoisotopic Mass 962.851371 g/mol
KOSTERAN-S/3 G Topological Polar Surface Area 108 Ų
KOSTERAN-S/3 G Heavy Atom Count 68
KOSTERAN-S/3 G Formal Charge 0
KOSTERAN-S/3 G Complexity 1100
KOSTERAN-S/3 G Isotope Atom Count 0
KOSTERAN-S/3 G Defined Atom Stereocenter Count 0
KOSTERAN-S/3 G Undefined Atom Stereocenter Count 4
KOSTERAN-S/3 G Defined Bond Stereocenter Count 0
KOSTERAN-S/3 G Undefined Bond Stereocenter Count 0
KOSTERAN-S/3 G Covalently-Bonded Unit Count 1
KOSTERAN-S/3 G Compound Is Canonicalized Yes
Kosteran-S/3 G is composed of Sorbitan Tristeareate. It functions as a W/O-emulsifier. This product is suitable for skin care creams and lotions, natural care, and colour cosmetics.KOSTERAN-S/3 G is a nonionic surfactant. It is variously used as a dispersing agent, emulsifier, and stabilizer, in food and in aerosol sprays. As a food additive, it has the E number E492. Brand names for polysorbates include Alkest, Canarcel, and Span. The consistency of KOSTERAN-S/3 G is waxy; its color is light cream to tan.KOSTERAN-S/3 G , also known as E492 or sorbester P38, belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups. KOSTERAN-S/3 G is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, KOSTERAN-S/3 G is primarily located in the membrane (predicted from logP).KOSTERAN-S/3 G is a nonionic surfactant. It is variously used as a dispersing agent, emulsifier, and stabilizer, in food and in aerosol sprays. As a food additive, it has the E number E492. Brand names for polysorbates include Alkest, Canarcel, and Span. The consistency of KOSTERAN-S/3 G is waxy; its color is light cream to tan.Pernetti et al. (2007) showed the structuring of edible oils using a mixture of sunflower lecithin and KOSTERAN-S/3 G (STS). Individually, neither of these components was by itself capable of inducing gelation even at concentrations as high as 20% w/w. However, when a mixture was used, structuring was achieved at concentrations of approximately 4% w/w. The mixture composition that resulted in structuring ranged between 2:3 lecithin:KOSTERAN-S/3 G to 3:2 lecithin:KOSTERAN-S/3 G . Microscopy of the gels showed the presence of needle-like crystals with lengths of approximately 10 μm. Preparations of only KOSTERAN-S/3 G in oil also showed the presence of crystalline particles, although these crystals had a lower aspect ratio (less needle-like) than when lecithin was present in the mixture. Lecithin was surmised to modify the crystal habit of the KOSTERAN-S/3 G crystals such that a more needle-like morphology resulted, which is more efficient at structuring oil. However, these gels melted at a low temperature (approximately 15°C) and were very sensitive to the addition of water, both of which would limit their utility in water-rich foods.Individually both lecithin (Lec) and KOSTERAN-S/3 G (STS) are incapable of forming oil gels at concentration between 6 and 20 %wt in absence of a polar solvent. However, when mixed in specific ratios between 40:60 to 60:40, Lec:KOSTERAN-S/3 G can form firm gels at a total concentration as low as 4 %wt (Pernetti et al., 2007). The crystalline units formed in these systems are based on KOSTERAN-S/3 G , while Lec plays an important role in influencing both the morphology of the crystalline units as well as the network junctions among the formed units. The gel however has limited use as hardstock fat replacer as it starts softening at temperature above 15 °C and undergoes complete collapse at 30 °C (Pernetti et al., 2007).In chocolate formulations surface-active substances are often used, for instance to reduce viscosity. Popular additives are KOSTERAN-S/3 G (STS), sorbitan monoesters, lecithin, mono- and diacylglycerols. Since roughly two-thirds of the chocolate recipe contains non-fat-soluble substances such as sugar and cocoa powder, the lecithin acts as a lubricant. The polar part of the lecithin covers the sugar particles, while the hydrophobic part faces the fat phase. Roughly 0.5 % is needed to cover the sugar and cocoa powder particles. The covered particles reduce the viscosity of the chocolate mass which is favourable. Lecithin itself is known to reduce the crystallization rate of fat indicating that the amount of lecithin should be controlled (Guth et al., 1989). Diacylglycerols also have a negative effect on the crystallization rate and on polymorphic transformation. However, there are several types of diacylglycerols each with different properties (Siew and Ng, 2000). For instance, it has been shown that 1.3-dipalmitin increases the melting point of the palm oil while 1.2-dipalmitin decreases the melting point.KOSTERAN-S/3 G is a component often used in CBR and CBS applications to stabilize β′ crystals (Wilson, 1999). It is shown to be one of the most effective emulsifiers for improving both initial gloss as well as bloom stability (Weyland, 1994). However, KOSTERAN-S/3 G also seems to have a negative effect on crystallization rate in these applications. Sorbitan monoesters and monoacylglycerols improve the crystallization rate in CBR and CBS systems because they are insoluble in the fat phase and act as nucleation agents. However, bloom stability does not seem to improve.In summary, the minor components in a fat play a crucial part in fat crystallization, yet there is inadequate understanding of the mechanisms behind their influence. The reason is that the levels are low and individual components often influence each other.KOSTERAN-S/3 G is a component often used in CBR and CBS applications to stabilize β′ crystals (Wilson, 1999). It is shown to be one of the most effective emulsifiers for improving both initial gloss as well as bloom stability (Weyland, 1994). However, KOSTERAN-S/3 G also seems to have a negative effect on crystallization rate in these applications.Lipophilic emulsifiers in the form of KOSTERAN-S/3 G (STS) are used as crystal-modifying agents in fats, where they prevent the formation of the high-melting β-crystal. The function of KOSTERAN-S/3 G is assumed to be due to its ability to co-crystallise with triacylglycerides in the β’-crystal form, preventing a solid-state crystal transition to the higher-melting β-crystal form during storage.7 Other emulsifiers, such as LACTEM or CITREM, provide a similar crystal-modifying function in cocoa butter substitutes (CBS) or cocoa butter replacers (CBR), but are less efficient than KOSTERAN-S/3 G .In the case of the transition from beta (V) into beta (VI), there are a number of possibilities. KOSTERAN-S/3 G (used to inhibit bloom in CBR and CBS systems as well) and similar emulsifiers reportedly slow the polymorphic transformation (Garti et al., 1986). If the desire is to avoid unnecessary items on the label, TAG solutions exist. Milk fat is well known for its bloom inhibiting effect; dark chocolate often has a small amount of milk fat added for this reason. More effective are bloom retarding fats that incorporate saturated TAG having mixed long (C16, C18) and medium (C10-C14) chain fatty acids (Cain et al., 1995). Thus, they are a specific type of lauric fat. They are stable in the beta′ polymorph.KOSTERAN-S/3 G (abbreviation STS), also known as Span 65, a nonionic surfactant that can be used as an emulsifier and stabilizer in food with the European food additive number E492. Its main functions are to retard fat bloom in chocolates and prevent cloudy appearance in cooking oils.Vegetable sourced stearic acid is the most used in the manufacturing process of KOSTERAN-S/3 G and other sorbitan esters of fatty acids. KOSTERAN-S/3 G is used as a water in oil (W/O) emulsifier and when used in combination with polysorbates they can stabilize oil in water (O/W) emulsions. The formulation of the Span/Polysorbate ratio can produce emulsifying systems with various HLB values. KOSTERAN-S/3 G is mainly used as an anti-bloom agent of fat, and also maintains the color and gloss in chocolates.KOSTERAN-S/3 G and lecithin are often used as surface-active substances to reduce viscosity in chocolate formulations. In chocolate, KOSTERAN-S/3 G adjusts sugar crystallization and appearance, also it can reduce stickiness.KOSTERAN-S/3 G is used as an emulsifier that can be used to retard fat bloom by preventing β’ crystals from converting to β crystals when exposed to excessive heat conditions, which tend to migrate to the chocolate surface and thus cause fat bloom. KOSTERAN-S/3 G can be used as an anti-crystallization agent in cooking oils (e.g. palm oil, coconut oil) to prevent oils cloudy appearance which are formed by harden-fast fractions under colder temperatures. KOSTERAN-S/3 G functions as a surfactant in cosmetics and personal care products. Its concentrations typically range between 0.1% and 5% (up to 10%). KOSTERAN-S/3 G has almost no side effects when used as a food additive. It is approved as an indirect food additive by the FDA.Yes, KOSTERAN-S/3 G would be halal, kosher and vegan if the raw material – stearic acid is from natural vegetable oils. However, some manufacturing processes may use stearic acid from animal fats and oils.KOSTERAN-S/3 G is used as an emulsifier and stabiliser. It is produced by the esterification of sorbitol with commercial stearic acid derived from food fats and oils.It is a mixture of the partial esters of sorbitol and its mono- and dianhydride with edible stearic acid.KOSTERAN-S/3 G is produced by the esterification of Sorbitol with commercial edible fatty acids and consists of approximately 95% of a mixture of the esters of Sorbitol and its mono and di-anhydrides.KOSTERAN-S/3 G is an effective emulsifier to retard fat bloom in chocolate. Fat used in chocolate, particularly cocoa butter, forms as a tightly packed β’ polymorph/crystal which is an unstable crystal but is vital for the functional and aesthetic quality of chocolate. If chocolate is not tempered properly or is exposed to excessive heat, these β’ crystals convert to β crystals which are less tightly packed but are more stable. These β crystals tend to migrate to the surface causing fat bloom to occur and also having a negative impact on the aesthetics of the chocolate.KOSTERAN-S/3 G ’s structure mimics the β’ crystals and bonds with such fat crystals and retards their conversion to the less desirable β crystals.KOSTERAN-S/3 G is used as a crystal inhibitor in oils which contain fractions that harden faster during colder temperatures making the oils look cloudy. This cloudy oil is perceived by many as deteriorated oil which it actually is not. It is just aesthetically unacceptable.The addition of KOSTERAN-S/3 G retards the harder fractions from nucleating at lower temperatures and causing cloudiness in oils.KOSTERAN-S/3 G has a structure more similar to a triglyceride than to an emulsifier.KOSTERAN-S/3 G has a structure more similar to a triglyceride than to an emulsifier.In 1947, Krantzconducted life-span studies with Sorbitan palmitate, Sorbitan stearate, KOSTERAN-S/3 G , and Sorbitan oleate. The study reports were only available as secondary source and therefore very limited in documentation of examinations and results. In each study, 30 male rats were exposed to a dietary concentration of 5% test substance in their daily diet, corresponding to 5000 mg/kg bw/d (calculation based on the assumption of an average body weight of 200 g and a daily average food consumption of 20 g). No treatment-related mortality or clinical signs as well as effects on body weights and histopathology were observed. Therefore, a NOAEL of≥5000 mg/kg bw/day was determined for Sorbitan palmitate, Sorbitan stearate, KOSTERAN-S/3 G , and Sorbitan oleate. Likewise, Sorbitan laurate was tested: male rats were fed the test substance in diet for 20.5 months at 5% and for 2 years at 10%, corresponding to 5000 and 10000 mg/kg bw/day (calculation based on the assumption of an average body weight of 200 g and a daily average food consumption of 20 g) (Barboriak 1970). Diarrhea and retarded growth were observed in the animals of the 10% dose group. No effects were observed at histopathology, therefore, a NOAEL was therefore set at 5000 mg/kg bw/d. The same NOAEL was determined in a second chronic study with rats that were fed 5% of the test substance in diet for 2 years (Krantz 1970). Again, no clinical signs were observed and mortality, body weight gain, haematology and histopathology were unaffected.
TR
KOSTERAN-S/3 G IUPAC Ad [2- (4-hidroksi-3-oktadekanoiloksioksolan-2-il) -2-oktadekanoiloksietil] oktadekanoat
KOSTERAN-S/3 G InChI = 1S / C60H114O8 / c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56 (62) 65- 53-55 (67-57 (63) 50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2) 60-59 (54 ( 61) 52-66-60) 68-58 (64) 51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3 / h54- 55,59-61H, 4-53H2,1-3H3
KOSTERAN-S/3 G InChI Anahtar IJCWFDPJFXGQBN-UHFFFAOYSA-N
KOSTERAN-S/3 G Kanonik SMILES CCCCCCCCCCCCCCCCCC (= O) OCC (C1C (C (CO1) O) OC (= O) CCCCCCCCCCCCCCCCC) OC (= O) CCCCCCCCCCCCCCCCC
KOSTERAN-S/3 G Moleküler Formül C60H114O8
KOSTERAN-S/3 G CAS 26658-19-5
KOSTERAN-S/3 G EC Numaras 247-891-4
KOSTERAN-S/3 G E numaras E492 (kvam arttrclar, …)
KOSTERAN-S/3 G Molar kütle 963,54 g / mol
KOSTERAN-S/3 G Görünüm Mumsu kat
KOSTERAN-S/3 G Fiziksel Tanm Sv; Dier Kat
KOSTERAN-S/3 G Form Sert, mumsu kat
KOSTERAN-S/3 G Ten Rengi Açk Krem
KOSTERAN-S/3 G Asit Deeri Max 7 mgKOH / gm
KOSTERAN-S/3 G Sabunlama Deeri 176-188 mgKOH / gm
KOSTERAN-S/3 G Nem içerii Maks.% 1
KOSTERAN-S/3 G Hidroksil Deeri 66-80 mgKOH / gm
KOSTERAN-S/3 G Ar Metaller (Pb olarak) 10mg / kg’dan az
KOSTERAN-S/3 G Arsenik 3 mg / kg’dan az
KOSTERAN-S/3 G Kadmiyum 1 mg / kg’dan az
KOSTERAN-S/3 G Cva 1 mg / kg’dan az
KOSTERAN-S/3 G Moleküler Arlk 963,5 g / mol
KOSTERAN-S/3 G XLogP3-AA 24.3
KOSTERAN-S/3 G Hidrojen Ba Donör Says 1
KOSTERAN-S/3 G Hidrojen Ba Alcs Says 8
KOSTERAN-S/3 G Dönebilen Tahvil Says 56
KOSTERAN-S/3 G Tam Kütle 962.851371 g / mol
KOSTERAN-S/3 G Monoizotopik Kütle 962.851371 g / mol
KOSTERAN-S/3 G Topolojik Polar Yüzey Alan 108 Ų
KOSTERAN-S/3 G Ar Atom Says 68
KOSTERAN-S/3 G Resmi arj 0
KOSTERAN-S/3 G Karmaklk 1100
KOSTERAN-S/3 G zotop Atom Says 0
KOSTERAN-S/3 G Tanml Atom Stereocenter Says 0
KOSTERAN-S/3 G Tanmsz Atom Stereo Merkez Says 4
KOSTERAN-S/3 G Tanml Bond Stereocenter Says 0
KOSTERAN-S/3 G Tanmsz Ba Stereocenter Says 0
KOSTERAN-S/3 G Kovalent Bal Birim Says 1
KOSTERAN-S/3 G Bileii Kanonikletirilmitir Evet
Kosteran-S / 3 G, Sorbitan Tristeareate’den oluur. W / O emülgatör olarak ilev görür. Bu ürün cilt bakm kremleri ve losyonlar, doal bakm ve renkli kozmetikler için uygundur. KOSTERAN-S/3 G noniyonik bir yüzey aktif maddedir. Yiyeceklerde ve aerosol spreylerde dispersiyon ajan, emülgatör ve stabilizatör olarak çeitli ekillerde kullanlr. Gda katk maddesi olarak E492 numarasna sahiptir. Polisorbatlarn marka isimleri Alkest, Canarcel ve Span’dr. KOSTERAN-S/3 G’nin kvam mumludr; Rengi açk kremden ten rengine kadardr. E492 veya sorbester P38 olarak da bilinen KOSTERAN-S/3 G, trikarboksilik asitler ve türevleri olarak bilinen organik bileikler snfna aittir. Bunlar tam olarak üç karboksil grubu içeren karboksilik asitlerdir. KOSTERAN-S/3 G, pratik olarak çözünmez (suda) ve nispeten nötr bir molekül olarak kabul edilir. KOSTERAN-S/3 G, hücre içinde öncelikle zarda bulunur (logP’den tahmin edilmektedir). KOSTERAN-S/3 G, iyonik olmayan bir yüzey aktif maddedir. Yiyeceklerde ve aerosol spreylerde dispersiyon ajan, emülgatör ve stabilizatör olarak çeitli ekillerde kullanlr. Gda katk maddesi olarak E492 numarasna sahiptir. Polisorbatlarn marka isimleri Alkest, Canarcel ve Span’dr. KOSTERAN-S/3 G’nin kvam mumludr; rengi açk kremden ten rengine kadardr. Pernetti et al. (2007), ayçiçei lesitini ve KOSTERAN-S/3 G (STS) karm kullanlarak yemeklik yalarn yaplandrlmasn gösterdi. Ayr ayr, bu bileenlerin hiçbiri,% 20 w / w kadar yüksek konsantrasyonlarda bile kendi bana jellemeyi indükleyemedi. Bununla birlikte, bir karm kullanldnda, yaplandrma, yaklak% 4 w / w konsantrasyonlarda gerçekletirildi. Yaplandrma ile sonuçlanan karm bileimi 2: 3 lesitin: KOSTERAN-S/3 G ile 3: 2 lesitin: KOSTERAN-S/3 G arasnda deiiyordu. Jellerin mikroskopisi, yaklak 10 um uzunluunda ine benzeri kristallerin varln göstermitir. Yada sadece KOSTERAN-S/3 G preparatlar da kristal parçacklarn varln gösterdi, ancak bu kristaller karmda lesitin bulunduundan daha düük bir en-boy oranna (daha az ine benzeri) sahipti. Lesitinin, KOSTERAN-S/3 G kristallerinin kristal eklini deitirdii tahmin edildi, öyle ki, yan yaplandrlmasnda daha verimli olan daha ine benzeri bir morfoloji elde edildi. Bununla birlikte, bu jeller düük bir scaklkta (yaklak 15 ° C) erimitir ve su ilavesine kar çok hassastrlar, her ikisi de sudan zengin gdalarda kullanmn snrlayacaktr. STS), polar bir çözücü olmadan arlkça% 6 ile% 20 arasndaki konsantrasyonda ya jelleri oluturamaz. Bununla birlikte, 40:60 ila 60:40 arasnda belirli oranlarda kartrldnda, Lec: KOSTERAN-S/3 G, arlkça% 4 kadar düük bir toplam konsantrasyonda sert jeller oluturabilir (Pernetti ve dierleri, 2007). Bu sistemlerde oluan kristalin birimler KOSTERAN-S/3 G’ye dayanrken, Lec hem kristalin birimlerin morfolojisini hem de oluturulan birimler arasndaki a balantlarn etkilemede önemli bir rol oynar. Bununla birlikte jel, sert stok ya olarak snrl kullanma sahiptir.15 ° C’nin üzerindeki scaklklarda yumuamaya baladnda ve 30 ° C’de tamamen çöktüünde eplacer (Pernetti ve dierleri, 2007). Çikolata formülasyonlarnda, örnein viskoziteyi azaltmak için genellikle yüzey aktif maddeler kullanlr. Popüler katk maddeleri KOSTERAN-S/3 G (STS), sorbitan monoesterler, lesitin, mono- ve diaçilgliserollerdir. Çikolata tarifinin kabaca üçte ikisi eker ve kakao tozu gibi yada çözünmeyen maddeler içerdiinden, lesitin bir kayganlatrc görevi görür. Lesitinin polar ksm eker parçacklarn kaplarken hidrofobik ksm ya fazna bakar. eker ve kakao tozu partiküllerini örtmek için kabaca% 0,5 gereklidir. Kaplanan partiküller, çikolata kütlesinin viskozitesini olumlu bir ekilde azaltr. Lesitinin kendisinin yan kristalleme orann düürdüü bilinmektedir, bu da lesitin miktarnn kontrol edilmesi gerektiini gösterir (Guth ve dierleri, 1989). Diaçilgliserollerin ayrca kristalleme hz ve polimorfik transformasyon üzerinde olumsuz bir etkisi vardr. Bununla birlikte, her biri farkl özelliklere sahip birkaç tip diaçilgliserol vardr (Siew ve Ng, 2000). Örnein 1.3-dipalmitinin hurma yann erime noktasn arttrd, 1.2-dipalmitinin ise erime noktasn düürdüü gösterilmitir. KOSTERAN-S/3 G, CBR ve CBS uygulamalarnda β ′ kristallerini stabilize etmek için sklkla kullanlan bir bileendir (Wilson, 1999). Hem balangç parlakln hem de çiçeklenme stabilitesini iyiletirmek için en etkili emülgatörlerden biri olduu gösterilmitir (Weyland, 1994). Ancak KOSTERAN-S/3 G’nin bu uygulamalarda kristalleme hzna da olumsuz etkisi olduu görülmektedir. Sorbitan monoesterleri ve monoasilgliseroller, ya faznda çözünmez olduklarndan ve çekirdeklenme ajanlar olarak görev yaptklarndan CBR ve CBS sistemlerinde kristalleme orann iyiletirir. Bununla birlikte, çiçeklenme stabilitesi iyilemi gibi görünmemektedir Özet olarak, bir yadaki küçük bileenler, ya kristallemesinde çok önemli bir rol oynamaktadr, ancak bunlarn etkisinin ardndaki mekanizmalar hakknda yetersiz anlay vardr. Bunun nedeni, seviyelerin düük olmas ve bireysel bileenlerin sklkla birbirini etkilemesidir. KOSTERAN-S/3 G, CBR ve CBS uygulamalarnda β ′ kristallerini stabilize etmek için sklkla kullanlan bir bileendir (Wilson, 1999). Hem balangç parlakln hem de çiçeklenme stabilitesini iyiletirmek için en etkili emülgatörlerden biri olduu gösterilmitir (Weyland, 1994). Bununla birlikte, KOSTERAN-S/3 G’nin bu uygulamalarda kristalleme hz üzerinde olumsuz bir etkisi olduu görülmektedir. KOSTERAN-S/3 G (STS) formundaki lipofilik emülgatörler, yalarda kristal modifiye edici ajanlar olarak kullanlrlar, yüksek erime noktal β-kristal. KOSTERAN-S/3 G’nin ilevinin, β’-kristal formundaki triasilgliseritlerle birlikte kristalleme kabiliyetinden kaynakland ve depolama srasnda daha yüksek erime noktal β-kristal forma kat hal kristal geçiini önledii varsaylmaktadr.7 Dier LACTEM veya CITREM gibi emülgatörler, kakao ya ikamelerinde (CBS) veya kakao ya ikamelerinde (CBR) benzer bir kristal deitirme ilevi salar, ancak KOSTERAN-S/3 G’den daha az etkilidir. ) beta (VI) ‘ya, bir dizi olaslk vardr. KOSTERAN-S/3 G (ayn zamanda CBR ve CBS sistemlerinde çiçeklenmeyi engellemek için kullanlr) ve benzer emülgatörlerin polimorfik dönüümü yavalatt bildirilmitir (Garti ve dierleri, 1986). Arzu etiket üzerinde gereksiz öelerden kaçnmaksa, TAG çözümleri mevcuttur. Süt ya, çiçeklenmeyi önleyici etkisiyle bilinir; bitter çikolata genellikle bu nedenle az miktarda süt ya içerir. Karma uzun (C16, C18) ve orta (C10-C14) zincir ya asitlerine sahip doymu TAG içeren çiçeklenme geciktirici yalar daha etkilidir (Cain ve dierleri, 1995). Bu nedenle, belirli bir laurik ya türüdür. Beta ′ polimorfunda stabildirler. KOSTERAN-S/3 G (ksaltma STS), ayn zamanda Span 65 olarak da bilinir, Avrupa gda katk maddesi numaras E492 ile gdalarda emülgatör ve stabilizatör olarak kullanlabilen noniyonik bir yüzey aktif madde. Balca ilevleri, çikolatalarda ya oluumunu geciktirmek ve yemeklik yalarda bulank görünümü önlemektir. Bitkisel kaynakl stearik asit, KOSTERAN-S/3 G ve dier ya asitlerinin sorbitan esterlerinin üretiminde en çok kullanlandr. KOSTERAN-S/3 G, yada su (W / O) emülgatör olarak kullanlr ve polisorbatlarla birlikte kullanldnda su (O / W) emülsiyonlarnda ya stabilize edebilir. Span / Polisorbat orannn formülasyonu, çeitli HLB deerlerine sahip emülsiyonlatrc sistemler üretebilir. KOSTERAN-S/3 G esas olarak yada çiçeklenme önleyici bir madde olarak kullanlr ve ayrca çikolatalarda renk ve parlakl korur.KOSTERAN-S/3 G ve lesitin, çikolata formülasyonlarnda viskoziteyi azaltmak için genellikle yüzey aktif maddeler olarak kullanlr. Çikolatada KOSTERAN-S/3 G eker kristallemesini ve görünümünü ayarlar, ayn zamanda yapkanl da azaltabilir. Β ‘kristallerinin ar maruz kaldnda β kristallere dönümesini önleyerek ya oluumunu geciktirmek için kullanlabilen bir emülgatör olarak kullanlr. çikolata yüzeyine göç etme eiliminde olan ve dolaysyla yaa neden olan s koullardokuma tezgah. KOSTERAN-S/3 G, daha souk scaklklarda sertlemeye hzl fraksiyonlarn oluturduu yalarn bulank görünümünü önlemek için yemeklik yalarda (örn. Hurma ya, hindistancevizi ya) anti-kristalizasyon ajan olarak kullanlabilir. KOSTERAN-S/3 G, kozmetik ve kiisel bakm ürünlerinde yüzey aktif madde olarak ilev görür. Konsantrasyonlar tipik olarak% 0,1 ile% 5 arasnda (% 10’a kadar) deiir. KOSTERAN-S/3 G, gda katk maddesi olarak kullanldnda hemen hemen hiçbir yan etkiye sahip deildir. FDA tarafndan dolayl gda katk maddesi olarak onaylanmtr.Evet, KOSTERAN-S/3 G, hammadde – stearik asit doal bitkisel yalardan ise helal, koer ve vegan olacaktr. Bununla birlikte, baz üretim süreçlerinde hayvansal kat ve sv yalardan elde edilen stearik asit kullanlabilir. KOSTERAN-S/3 G, emülgatör ve stabilizatör olarak kullanlr. Sorbitolün, gda yalarndan elde edilen ticari stearik asit ile esterletirilmesiyle üretilir.Sorbitolün ksmi esterleri ile mono- ve dianhidritinin yenilebilir stearik asit ile karmdr.KOSTERAN-S/3 G, Ticari yenilebilir ya asitleri içeren sorbitol ve yaklak% 95 Sorbitol esterleri ile onun mono ve di-anhidritlerinin karmndan oluur KOSTERAN-S/3 G, çikolatadaki ya oluumunu geciktirmek için etkili bir emülgatördür. Çikolatada kullanlan ya, özellikle kakao ya, kararsz bir kristal olan ancak çikolatann ilevsel ve estetik kalitesi için hayati önem tayan, skca paketlenmi bir “polimorf / kristal” olarak oluur. Çikolata uygun ekilde temperlenmezse veya ar sya maruz kalrsa, bu β ‘kristalleri daha az sk paketlenmi ancak daha stabil olan β kristallere dönüür. Bu β kristalleri yüzeye göç etme eiliminde olup ya oluumuna neden olur ve ayrca çikolatann estetiini olumsuz etkiler. KOSTERAN-S/3 G’nin yaps β ‘kristallerini taklit eder ve bu tür ya kristalleri ile balanr ve bunlarn KOSTERAN-S/3 G, daha düük scaklklarda daha hzl sertleerek yalar bulutlu gösteren fraksiyonlar içeren yalarda kristal inhibitörü olarak kullanlr. Bu bulank ya, pek çok kii tarafndan aslnda olmad kadar bozulmu ya olarak alglanmaktadr. Sadece estetik olarak kabul edilemez. KOSTERAN-S/3 G ilavesi, sert fraksiyonlarn daha düük scaklklarda çekirdeklenmesini ve yalarda bulankla neden olmasn geciktirir KOSTERAN-S/3 G, emülgatörden çok trigliseride benzer bir yapya sahiptir. bir emülgatörden çok bir trigliseride benzeyen bir yap. 1947’de Krantz, Sorbitan palmitat, Sorbitan stearat, KOSTERAN-S/3 G ve Sorbitan oleat ile yaam süresi çalmalar yürüttü. Çalma raporlar sadece ikincil kaynak olarak mevcuttu ve bu nedenle snavlarn ve sonuçlarn dokümantasyonunda çok snrlyd. Her çalmada, 30 erkek sçan, günlük diyetlerinde 5000 mg / kg canl arlk / güne tekabül eden% 5’lik bir diyet konsantrasyonuna maruz braklmtr (hesaplama, ortalama vücut arl 200 g ve günlük ortalama varsaymna dayanmaktadr). 20 g gda tüketimi). Tedaviye bal hiçbir ölüm veya klinik belirti ile vücut arlklar ve histopatoloji üzerindeki etkiler gözlenmedi. Bu nedenle Sorbitan palmitat, Sorbitan stearat, KOSTERAN-S/3 G ve Sorbitan oleat için> 5000 mg / kg canl arlk / gün NOAEL belirlendi. Benzer ekilde, Sorbitan laurat test edildi: erkek sçanlar, 5000 ve 10000 mg / kg canl arlk / güne karlk gelen, 20.5 ay boyunca% 5 orannda ve 2 yl boyunca% 10 orannda diyette test maddesi ile beslendi vücut arl 200 gr ve günlük ortalama gda tüketimi 20 gr) (Barboriak 1970). % 10 doz grubundaki hayvanlarda ishal ve büyüme gerilii gözlendi. Histopatolojide hiçbir etki gözlenmedi, bu nedenle bir NOAEL 5000 mg / kg bw / gün olarak ayarland. Ayn NOAEL, 2 yl boyunca diyette test maddesinin% 5’ini besleyen sçanlarla yaplan ikinci bir kronik çalmada belirlenmitir (Krantz 1970). Yine hiçbir klinik belirti gözlenmedi ve mortalite, vücut arl art, hematoloji ve histopatoloji etkilenmedi.