N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone, also called NMP, N-methyl pyrrolidinone, N-methyl-2-pyrrolidon, or 1-methyl-2-pyrrolidone, is a highly polar, aprotic organic solvent with a low viscosity.
N-Methyl-2-pyrrolidone is readily miscible with water and other organic solvents and is widely used in many applications.
N-Methyl-2-pyrrolidone (NMP) is a powerful, aprotic solvent with high solvency and low volatility.
This colorless, high boiling, flash point, and low vapor pressure liquid carries a mild amine-like odor.
N-Methyl-2-pyrrolidone has high chemical and thermal stability and is completely miscible with water at all temperatures.
N-Methyl-2-pyrrolidone is a co-solvent with water, alcohols, glycol ethers, ketones, and aromatic/chlorinated hydrocarbons.
N-Methyl-2-pyrrolidone is both recyclable by distillation and readily biodegradable.
N-Methyl-2-pyrrolidone is a versatile solvent for numerous applications, including graffiti removal, automotive and industrial cleaning, water-borne coatings, and photoresist stripping.
EC / List no.: 212-828-1
CAS no.: 872-50-4
Mol. formula: C5H9NO
Synonyms of N-Methyl-2-pyrrolidone: N-methylpyrrolidone, NMP, N-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidinone, 1-methyl-2-pyrrolidone, 1-Methyl-5-pyrrolidinone, 1-Methylpyrrolidin-2-one, N-Methyl-2-pyrrolidinone, N-Methylpyrrolidinone, N-Methylpyrrolidone, Pharmasolve, Pyrol M, 1-Methyl-2-pyrrolidone (NMP), 1-Methyl-2-pyrrolidinone,N-methyl pyrrolidinone, 1-Methyl-2-pyrrolidon, 1-methylpyrrolidin-1-one, N-Methyl-2-pyrrolidon, M-Pyrol
Chemical formula: C5H9NO
Molar mass: 99.133 g·mol−1
Density: 1.028 g/cm3
Melting point: −24 °C (−11 °F; 249 K)
Boiling point: 202 to 204 °C (396 to 399 °F; 475 to 477 K)
Solubility in water: Soluble
Solubility in Ethanol, acetone, diethyl ether, ethyl acetate, chloroform, benzene
log P: −0.40
APPLICATIONS OF N-Methyl-2-pyrrolidone:
1) Electronics
Wax, flux removal
Burr removal
Electronic parts cleaning
Semiconductor parts cleaning
Solvent for lithium battery manufacturing
Semiconductor photo-resist thinner
Color filter photo-resist thinner
Electronics.
N-Methyl-2-pyrrolidone has been used in electronics for many years as a photoresist stripper.
With the phase-out of CFCs, NMP has gained widespread acceptance as a solvent in other electronic applications, including semi-aqueous de-fluxing, degreasing, and coatings (polyamide, epoxy, and polyurethane).
Graffiti Removers.
N-Methyl-2-pyrrolidone-based graffiti removers combine high performance and biodegradability with low volatility and flammability.
N-Methyl-2-pyrrolidone can be blended with glycol ethers or acetates such as Glycol Ether PMA, PEA, and DPMA; they are cost-effective and improve performance on surfaces defaced by lipstick and crayon graffiti.
2) Automotive and Coatings
Mold cleaning
Metal (parts) cleaning
Coatings Solvent.
N-Methyl-2-pyrrolidone is a powerful solvent for most commercial resins.
Due to its high boiling point and excellent solvent power, N-Methyl-2-pyrrolidone extends and improves the properties of high-temperature bake coatings.
For instance, high solid binders are more easily obtained with NMP as the solvent.
Quite often, baked finishes yield coatings with outstanding mechanical and dielectric properties.
N-Methyl-2-pyrrolidone also aids rheological control: better flow and leveling -less cratering and pin holing.
For these reasons, N-Methyl-2-pyrrolidone is highly effective in wire coating and other high-temperature coating applications.
N-Methyl-2-pyrrolidone is also the preferred solvent for urethane dispersions and is an excellent coalescent for acrylic and styrene acrylic latexes.
3) Chemical
Extract agent (acetylene, BTX, butadiene)
Synthetic resin surface coating solvent
Reaction solvents (PPS, polyimide, etc.)
Equipment washing
Due to its high solvency and low volatility, N-Methyl-2-pyrrolidone is used in Equipment washing solvent formulations including hydrocarbons, terpenes, propylene carbonate, and P-Series glycol ethers.
4) Optical
Plastic lens manufacturing equipment cleaning
5) Pharmaceutical and Agricultural Chemicals
Water-soluble solvent
Cleaning
Extraction
Agricultural.
The agricultural chemical industry takes advantage of N-Methyl-2-pyrrolidone’s solvency and handling properties in agricultural formulations.
N-Methyl-2-pyrrolidone can suitably be used as a solvent, especially in agricultural applications, including Alachlor, Propoxur, Oxyfluorfen, Difenoconazole, Trifluralin, Triadimenol, Tebuconazole, Pendimethalin, Propanil, Phenmedipham, Alpha-Cypermethrin, and Chlorpyrifos formulations.
Consumer and Industrial Cleaners.
N-Methyl-2-pyrrolidone is an effective stripping agent in floor stripping, oven cleaners, graffiti removers, and paint strippers.
Due to its high solvency and low volatility, N-Methyl-2-pyrrolidone is used in automotive and industrial cleaners with solvents such as hydrocarbons, terpenes, propylene carbonate, and P-Series glycol ethers.
N-Methyl-2-pyrrolidone can be used for various industrial cleaning purposes, such as in the textile industry, for removing polymeric materials, dyes, and other contaminants.
These cleaning purposes include use as an efficient stripping agent for varnishes, paints, and other finishes based on cellulose, vinyl, acrylic, and other resins.
Another example of N-Methyl-2-pyrrolidone’s usage is removing carbon deposits and other combustion products from combustion engines.
Petrochemical Processing.
N-Methyl-2-pyrrolidone has been shown to have a selective affinity for unsaturated hydrocarbons, aromatics, and sulfur-bearing gases.
Due to its relative non-reactivity and high solvency, N-Methyl-2-pyrrolidone finds broad applicability as an extraction solvent in lube oil processing and natural and synthetic gas purification.
Miscellaneous Solvent Applications.
The excellent thermal and chemical stability of NMP enhances its utility as a solvent or co-solvent in many synthetic reaction systems.
N-Methyl-2-pyrrolidone shows a selective affinity for unsaturated hydrocarbons, aromatics, and sulfur compounds.
N-Methyl-2-pyrrolidone can co-solvent with water, aromatic/chlorinated hydrocarbons, alcohols, glycol ethers, and ketones.
N-Methyl-2-pyrrolidone is hygroscopic (picks up moisture) but stable under normal conditions.
N-Methyl-2-pyrrolidone will violently react with strong oxidizers such as hydrogen peroxide, nitric acid, sulfuric acid, etc.
The primary decomposition products produce carbon monoxide and nitrogen oxide fumes.
N-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone or NMP, has been an essential solvent for fluorinated coatings.
N-Methyl-2-pyrrolidone is a very slow-evaporating solvent.
N-Methyl-2-pyrrolidone is a solvent for agricultural formulations and synthesis applications such as insecticides, fungicides, and herbicides.
N-Methyl-2-pyrrolidone solvent, a lower alkyl pyrrolidone, is a potent and versatile aprotic solvent.
N-Methyl-2-pyrrolidone’s high boiling point, low vapor pressure, and high stability make it an effective solvent in numerous industrial applications. N-Methyl-2-pyrrolidone can be used as a co-solvent with water, alcohol, and other organic substances.
N-Methyl-2-pyrrolidone solvent is highly resistant to hydrolysis from pH 2-10, even at elevated temperatures.
N-Methyl-2-pyrrolidone (NMP) is a versatile water-miscible polar aprotic solvent. N-Methyl-2-pyrrolidone is used as a drug solubilizer and penetration enhancer in humans and animals.
N-Methyl-2-pyrrolidone is freely soluble in polar and nonpolar solvents and should readily cross biological membranes. N-Methyl-2-pyrrolidone is quickly absorbed from human skin and gastrointestinal and respiratory tracts.
N-Methyl-2-pyrrolidone has been used for dissolving some binder resins, such as polyamide/imide (PAI) or polyethersulfone (PES), used in fluoropolymer-based one-coats and primers.
N-Methyl-2-pyrrolidone, commonly referred to as N-Methyl-2-pyrrolidone, NMP, or M-Pyrol, is used within the semiconductor industry as a degreaser, a resist stripper and a solvent for phenolic die coat resins
N-Methyl-2-pyrrolidone is used to recover certain hydrocarbons generated in the processing of petrochemicals, such as the recovery of 1,3-butadiene and acetylene.
N-Methyl-2-pyrrolidone absorbs hydrogen sulfide from sour gas and hydrodesulfurization facilities.
NMP is a high boiling liquid with very high solubility for H2S
NMP is a non-volatile polar solvent with a strong affinity for H2S and CO2.
N-Methyl-2-pyrrolidone’s good solvency properties have led to N-Methyl-2-pyrrolidone’s use to dissolve a wide range of polymers.
Specifically, N-Methyl-2-pyrrolidone is used as a solvent for the surface treatment of textiles, resins, and metal-coated plastics or as a paint stripper.
N-Methyl-2-pyrrolidone is also used as a solvent in commercially preparing polyphenylene sulfide.
In the pharmaceutical industry, N-Methyl-2-pyrrolidone is used in the formulation of drugs by both oral and transdermal delivery routes.
N-Methyl-2-pyrrolidone is also used heavily in lithium-ion battery fabrication as a solvent for electrode preparation. N-Methyl-2-pyrrolidone has a unique ability to dissolve polyvinylidene fluoride binder.
Due to N-Methyl-2-pyrrolidone’s toxicity and high boiling point, there is much effort to replace it in battery manufacturing with another solvent(s), like water.
N-Methyl-2-pyrrolidone is a 5-member-ring compound containing nitrogen. N-Methyl-2-pyrrolidone has many uses due to the following excellent characteristics.
N-Methyl-2-pyrrolidone is highly polar and miscible with most organic solvents (alcohols, ethers, ketones, aromatic hydrocarbons, chlorinated hydrocarbons, etc.).
Organic and inorganic substances are highly soluble in N-Methyl-2-pyrrolidone.
N-Methyl-2-pyrrolidone mixes with water in all proportions.
N-Methyl-2-pyrrolidone has a high flash point compared to similar solvents.
The boiling point of N-Methyl-2-pyrrolidone is high, the freezing point is low, and handling is easy.
N-Methyl-2-pyrrolidone is chemically and thermally stable and not corrosive.
N-Methyl-2-pyrrolidone is used to produce fine chemicals from mass-produced chemicals.
N-Methyl-2-pyrrolidone applications in the electronics field have expanded in recent years.
N-Methyl-2-pyrrolidone’s high polarity and solvency power and our high purity, high-grade production technology enable the high performance needed in this field.
N-Methyl-2-pyrrolidone can dissolve organic and inorganic compounds equally or better than chlorofluorocarbon solvents.
Therefore N-Methyl-2-pyrrolidone is used in various industrial fields as a cleaning or release agent.
N-Methyl-2-pyrrolidone is replacing 1,1,1-trichloroethane in metal cleaning applications due to the worldwide environmental pollution problems associated with chlorinated solvents.
N-Methyl-2-pyrrolidone is a solvent used in various industries and applications, such as paint and coating removal, petrochemical processing, engineering plastics coatings, agricultural chemicals, electronic cleaning, and industrial/ domestic cleaning.
Due to its good solvency properties, N-Methyl-2-pyrrolidone dissolves a wide range of polymers.
N-Methyl-2-pyrrolidone is used in the surface treatment of textiles, resins, and metal-coated plastics or as a paint stripper.
Substance names and other identifiers
Regulatory process names
1-Methyl-2-pyrrolidinone
1-methyl-2-pyrrolidone
EC Inventory, Pre-Registration process, Other
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-2-pyrrolidone (NMP)
1-Methyl-5-pyrrolidinone
1-Methylazacyclopentan-2-one
1-Methylpyrrolidin-2-one
1-Methylpyrrolidinone
1-Methylpyrrolidone
2-Pyrrolidinone, 1-methyl-
AgsolEx 1
Methylpyrrolidone
Microposit 2001
N-Methyl-2-pyrrolidinone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone
N-Methyl-gamma-butyrolactam
N-Methylpyrrolidinone
N-Methylpyrrolidone
N-methylpyrrolidone
NMP
Pharmasolve
Pyrol M
SL 1332
Translated names
1-methyl-2-pyrrolidon (da)
1-Methyl-2-pyrrolidon (de)
1-methyl-2-pyrrolidon (nl)
1-methylpyrrolidin-2-on (cs)
1-metil-2-pirolidon (hr)
1-metil-2-pirolidon (sl)
1-metil-2-pirolidonas (lt)
1-metil-2-pirolidons (lv)
1-metil-2-pirolidonă (ro)
1-metil-2-pirrolidon (hu)
1-metil-2-pirrolidon (mt)
1-metil-2-pirrolidona (es)
1-metil-2-pirrolidona (pt)
1-metil-2-pirrolidone (it)
1-metyl-2-pyrrolidon (no)
1-metyl-2-pyrrolidon (sv)
1-metylo-2-pirolidon (pl)
1-metylpyrolidín-2-ón (sk)
1-metyyli-2-pyrrolidoni (fi)
1-metüül-2-pürrolidoon (et)
1-méthyl-2-pyrrolidone (fr)
1-μεθυλο-πυρρολιδόνη-2 (el)
1-метил-2-пиролидон (bg)
<I>N</I>-metil-2-pirolidon (hr)
N-methyl-2-pyrrolidon (cs)
N-methyl-2-pyrrolidon (da)
N-Methyl-2-pyrrolidon (de)
N-methyl-2-pyrrolidon (nl)
N-metil-2-pirolidon (sl)
N-metil-2-pirolidonas (lt)
N-metil-2-pirolidons (lv)
N-metil-2-pirolidonă (ro)
N-metil-2-pirrolidon (hu)
N-metil-2-pirrolidon (mt)
N-metil-2-pirrolidona (es)
N-metil-2-pirrolidona (pt)
N-metil-2-pirrolidone (it)
N-metyl-2-pyrolidón (sk)
N-metyl-2-pyrrolidon (no)
N-metyl-2-pyrrolidon (sv)
N-metylo-2-pirolidon (pl)
N-metyyli-2-pyrrolidoni (fi)
N-metüül-2-pürrolidoon (et)
N-méthyl-2-pyrrolidone (fr)
N-μεθυλο-πυρρολιδόνη-2· (el)
N-метил-2-пиролидон (bg)
CAS names
2-Pyrrolidinone, 1-methyl-
IUPAC names
1-mehyl-2-pyrrolodone
1-Methyl 2-pyrrolidone
1-methyl 2-pyrrolidone
1-Methyl-2-pyrrolidinone
1-methyl-2-pyrrolidon
1-Methyl-2-Pyrrolidone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-2-pyrrolidone (NMP)
1-methylpyrrolidin-1-one
1-methylpyrrolidin-2-one
1-methylpyrrolidin-2-one,N-METHYLPYRROLIDONE, 1-Methyl-2-pyrrolidinone, N-Methyl-2-pyrrolidone
1-methylpyrrolidone
1-méthyl-2-pyrrolidone
1-O-butyl 2-O-(phenylmethyl) benzene-1,2-dicarboxylate
2-Pyrrolidinone, 1-methyl-
2-Pyrrolidone, 1-methyl
Methyl pyrrolidone
METHYL-N 2-PYRROLIDONE
n methyl 2 pyrrolidone
N-Methyl pyrolidone
N-methyl-2-pyrolidone
N-Methyl-2-pyrrolidinone
N-Methyl-2-pyrrolidon
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone
N-Methylpyrrolidone
N-Methylpyrrolidone
NMP
NMP
NMP (N-Methyl-2-pyrrolidone)
Trade names
1-Methyl-2-pyrrolidinone
1-Methyl-2-pyrrolidone
1-methyl-2-pyrrolidone
1-Methyl-5-pyrrolidinone
1-Methylazacyclopentan-2-one
1-Methylpyrrolidinone
1-Methylpyrrolidone
2-Pyrrolidinone, 1-methyl- (7CI, 8CI, 9CI)
2-Pyrrolidinone, 1-methyl-(7Cl, 8Cl, 9Cl)
M-Pyrol
N-Methyl pyrrolidone
N-methyl pyrrolidone
N-Methyl-.gamma.-butyrolactam
N-Methyl-2-pyrrolidinone
N-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidone
N-Methyl-Pyrrolidone
N-Methyl-α-pyrrolidinone
N-Methyl-α-pyrrolidone
N-METHYLPYROLIDONE
N-Methylpyrrolidinone
N-Methylpyrrolidon
n-methylpyrrolidon in Lube Green preparation
N-Methylpyrrolidone
NMP
POLYFLON PTFE SM-3900
Pyrol-M
Other names
NMP
Other identifiers
26138-58-9
CAS number
26138-58-9
Deleted CAS number
53774-35-9
CAS number
53774-35-9
Deleted CAS number
57762-46-6
CAS number
57762-46-6
Deleted CAS number
606-021-00-7
Index Number
872-50-4