PEG 4000 (POLYETHYLENE GLYCOL 4000)
PEG 4000 (POLYETHYLENE GLYCOL 4000)
CAS No. : 25322-68-3
EC No. : 500-038-2
Synonyms:
ETHYLENE GLYCOL; 1,2-ethanediol; Ethane-1,2-diol; 107-21-1; glycol; monoethylene glycol; 1,2-Dihydroxyethane; 2-hydroxyethanol; Glycol alcohol; Ethylene alcohol; polyethylene glycol; Macrogol; Fridex; Tescol; Ethylene dihydrate; Norkool; Macrogol 400 BPC; Dowtherm SR 1; ethanediol; Zerex; Ucar 17; Lutrol-9; Polyethylene glycol 200; ethyleneglycol; Aethylenglykol; Glycol, ethylene-; 1,2-Ethandiol; Glycols, polyethylene; Caswell No. 441; Ethylenglycol; Aethylenglykol [German]; ethylen glycol; ethylene-glycol; Lutrol; PEG 400; Polyethylene glycol 600; 146AR; Polyethylene glycol 1000; UNII-FC72KVT52F; Lutrol 9; Carbowax 20; MFCD00002885; NSC 93876; Carbowax 300; Carbowax 400; CCRIS 3744; Carbowax 1000; Dowtherm 4000; 1,2-ethylene glycol; 1,2-dihydroxy ethane; Ethylene glycol polymer; HSDB 5012; NCI-C00920; HOCH2CH2OH; Union Carbide XL 54 Type I De-icing Fluid; PEG 3350; EINECS 203-473-3; M.e.g.; Ethylene glycol homopolymer; Polyethylene Glycol 4000; EPA Pesticide Chemical Code 042203; 1,2-Ethanediol homopolymer; FC72KVT52F; AI3-03050; PEG; DTXSID8020597; CHEBI:30742; PEG 4000; 1, 2-Ethanediol; DuPont Zonyl FSO Fluorinated Surfactants; alpha-Hydro-omega-hydroxypoly(oxyethylene); DSSTox_CID_597; Poly(oxy-1,2-ethanediyl), alpha-hydro-omega-hydroxy-; Poly(oxy-1,2-ethanediyl, alpha-hydro-omega-hydroxy-; F0001-0142; 004143F9-240E-472F-9D5A-B1B13BBA2A18; Ethylene glycol, United States Pharmacopeia (USP) Reference Standard; Ethylene glycol, Pharmaceutical Secondary Standard; Certified Reference Material; Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 3 mm x 8 in.; Ethylene glycol solution, NMR reference standard, 80% in DMSO-d6 (99.9 atom % D), NMR tube size 5 mm x 8 in.; ethylene glycol;1,2-ethanediol;ethane-1,2-diol;glycolethylene glycol;ethanediol;ethylene glycol 1,2-ethanediol ethane-1,2-diol glycolethylene glycol ethanediol
EN
PEG 4000 Applications
PEG 4000 Application Polyethylene glycol 1500 for synthesis. CAS 25322-68-3, pH 4 – 7 (100 g/l, H₂O, 20 °C).
PEG 4000 Physicochemical Information
PEG 4000 Boiling point >200 °C (1013 hPa)
PEG 4000 Density 1.2 g/cm3 (20 °C)
PEG 4000 Flash point 240 °C
PEG 4000 Ignition temperature 420 °C
PEG 4000 Melting Point 43 – 49 °C
PEG 4000 pH value 4 – 7 (100 g/l, H₂O, 20 °C)
PEG 4000 Vapor pressure <0.01 hPa (20 °C)
PEG 4000 Bulk density 400 – 500 kg/m3
PEG 4000 Solubility 650 g/l
PEG 4000 Toxicological Information
PEG 4000 LD 50 oral LD50 Rat 28000 mg/kg
PEG 4000 LD 50 dermal LD50 Rabbit > 20000 mg/kg
PEG 4000 Safety Information according to GHS
PEG 4000 Storage class 10 Combustible liquids
PEG 4000 WGK WGK 1 slightly hazardous to water
PEG 4000 Disposal 3
PEG 4000 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
PEG 4000 Storage and Shipping Information
PEG 4000 Storage Store below +30°C.
PEG 4000 Transport Information
PEG 4000 Declaration (railroad and road) ADR, RID Kein Gefahrgut
PEG 4000 Declaration (transport by air) IATA-DGR No Dangerous Good
PEG 4000 Declaration (transport by sea) IMDG-Code No Dangerous Good
PEG 4000 Specifications
PEG 4000 Melting range (lower value) ≥ 43 °C
PEG 4000 Melting range (upper value) ≤ 49 °C
PEG 4000 Hydroxyl value 70 – 80
PEG 4000 Average molecular mass 1400 – 1600
PEG 4000 Identity (IR) passes test
Activated PEG 4000s (for conjugation to biologics)
PEG 4000-PLA or PEG 4000-PLGA (for nanoparticle formulations of drugs)
Linear and branched functionalized polyethylene imines and other polyimines (for oligo-nucleotide binding and delivery)
PEG 4000-pAsp / PEG 4000-pGlu (for oligo-nucleotide binding and delivery)
Hyperbranched polyglycerols (for drug delivery and protein formulation)
Other polymers for nanoparticle formation (drug delivery)
Poly(ethylene glycol) (PEG 4000) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG 4000 and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG 4000 also interacts with cell membrane, thereby allowing cell fusion.Polyethylene Glycol 1500 (PEG 4000-1500) has been used to mediate cell fusion.PEG 4000 is a polymer of ethylene oxide with an average molecular weight of 1500. This polymeric material is an excellent solubiliser and can be used in a wide variety of home care and I&I applications.Polyethylene glycol. PEG- 1500 by Dynamic International is a surfactant. It is available in the form of milky white solid. PEG- 1500 is used in cream and shampoo base material.Crystallization grade Polyethylene glycol 1500(PEG 4000) for formulating screens or for optimization.PEG 4000 Eye contact Unlikely to cause eye irritation in man.PEG 4000 Skin contact Unlikely to cause skin irritation in man.PEG 4000 Inhalation This material may cause irritation following inhalation.PEG 4000 Ingestion Will cause irritation of the gastrointestinal tract.Low oral toxicity, but ingestion may cause irritation of the gastrointestinal tract.PEG 4000 Eye contact Irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.PEG 4000 Skin contact Remove contaminated clothing. Wash skin with soap and water. If symptoms develop, obtain medical attention.PEG 4000 Inhalation Remove patient from exposure. Obtain medical attention if ill effects occur.PEG 4000 Ingestion Do not induce vomiting. Wash out mouth with water and give 200-300 ml (half a pint) of water to drink. Obtain medical attention if ill effects occur.PEG 4000 Further Medical Treatment Symptomatic treatment and supportive therapy as indicated.PEG 4000 Extinguishing Media Water fog, alcohol foam, carbon dioxide, dry chemical.PEG 4000 Unsuitable Extinguishing Media None known.PEG 4000 Special fire-fighting protective equipment A self contained breathing apparatus and suitable protective clothing must be worn in fire conditions.PEG 4000 Fire and explosion hazards Combustible but not readily ignited.
PEG 4000 Colour white
PEG 4000 Form solid
PEG 4000 Odour mild
PEG 4000 pH approx 5 – 7 5% In water
PEG 4000 Boiling point/boiling range (°C) No data.
PEG 4000 Flash Point (ºC) > 260 (open cup)
PEG 4000 Autoignition Temperature (ºC) approx 420
PEG 4000 Flammable Limits No data.
PEG 4000 Explosive Properties No data.
PEG 4000 Oxidising Properties No data.
PEG 4000 Vapour Density No data.
PEG 4000 Solubility in water soluble
PEG 4000 Solubility in other ingredients Soluble in many organic solvents, insoluble in:, aliphatic hydrocarbons
PEG 4000 Partition Coefficient No data.
PEG 4000 Dynamic viscosity (mPa.s) approx 30 @99°C
PEG 4000 Density (g/ml) 1.208 @ 20 °C
PEG 4000 Stability Stable under normal conditions.
PEG 4000 Materials to avoid Strong oxidising agents.
PEG 4000 Conditions to avoid None known
PEG 4000 Hazardous decomposition products None known
PEG 4000 Hazardous polymerisation Will not occur
TR
PEG 4000 Uygulamalar
PEG 4000 Uygulama Polietilen glikol 1500 sentez için. CAS 25322-68-3, pH 4-7 (100 g / l, H₂O, 20 ° C).
PEG 4000 Fizikokimyasal Bilgiler
PEG 4000 Kaynama noktas> 200 ° C (1013 hPa)
PEG 4000 Younluk 1.2 g / cm3 (20 ° C)
PEG 4000 Parlama noktas 240 ° C
PEG 4000 Tutuma scakl 420 ° C
PEG 4000 Erime Noktas 43-49 ° C
PEG 4000 pH deeri 4-7 (100 g / l, H₂O, 20 ° C)
PEG 4000 Buhar basnc <0.01 hPa (20 ° C)
PEG 4000 Yn younluu 400 – 500 kg / m3
PEG 4000 Çözünürlük 650 g / l
PEG 4000 Toksikolojik Bilgi
PEG 4000 LD 50 oral LD50 Sçan 28000 mg / kg
PEG 4000 LD 50 dermal LD50 Tavan> 20000 mg / kg
GHS’ye göre PEG 4000 Güvenlik Bilgileri
PEG 4000 Depolama snf 10 Yanc svlar
PEG 4000 WGK WGK 1 su için hafif tehlikeli
PEG 4000 mha 3
PEG 4000 Nispeten reaktif olmayan organik reaktifler A kabnda toplanmaldr. Halojenlenmise, bunlar kap B’de toplanmaldr. Kat kalntlar için kap C’yi kullann.
PEG 4000 Saklama ve Nakliye Bilgileri
PEG 4000 Depolama + 30 ° C’nin altnda saklayn.
PEG 4000 Tama Bilgileri
PEG 4000 Beyan (demiryolu ve karayolu) ADR, RID Kein Gefahrgut
PEG 4000 Beyan (hava yoluyla tama) IATA-DGR Tehlikeli Madde Yok
PEG 4000 Beyan (deniz yoluyla tama) IMDG-Kodu Tehlikeli Mal Yok
PEG 4000 Özellikleri
PEG 4000 Erime aral (düük deer) ≥ 43 ° C
PEG 4000 Erime aral (üst deer) ≤ 49 ° C
PEG 4000 Hidroksil deeri 70 – 80
PEG 4000 Ortalama moleküler kütle 1400 – 1600
PEG 4000 Kimlik (IR) testi geçti
Aktifletirilmi PEG 4000’ler (biyolojikle elenik için)
PEG 4000-PLA veya PEG 4000-PLGA (nanopartikül ilaç formülasyonlar için)
Dorusal ve dall ilevselletirilmi polietilen iminler ve dier poliiminler (oligo-nükleotid balanmas ve datm için)
PEG 4000-pAsp / PEG 4000-pGlu (oligo-nükleotid balanmas ve datm için)
Ar dallanm poligliseroller (ilaç datm ve protein formülasyonu için)
Nanopartikül oluumu için dier polimerler (ilaç datm)
Poli (etilen glikol) (PEG 4000) iyonik olmayan hidrofilik bir polimerdir ve farkl moleküler arlklarda mevcuttur. Proteinlerin ve nükleik asitlerin saflatrlmasna ve kristal büyümesine yardmc olur. PEG 4000 ve dekstran birlikte biyolojik materyallerin saflatrlmas için gerekli olan sulu polimer iki fazl sistem ile sonuçlanr. PEG 4000 ayrca hücre zar ile etkileime girerek hücre füzyonuna izin verir. Hücre füzyonuna araclk etmek için Polietilen Glikol 1500 (PEG 4000-1500) kullanlmtr. PEG 4000, ortalama molekül arl 1500 olan bir etilen oksit polimeridir. Bu polimerik malzeme mükemmel bir çözündürücüdür ve çok çeitli evde bakm ve I&I uygulamalarnda kullanlabilir. Polietilen glikol. Dynamic International tarafndan sunulan PEG-1500 bir yüzey aktif maddedir. Süt beyaz kat formda mevcuttur. PEG-1500, krem ve ampuan esasl malzemede kullanlr. Ekranlarn formüle edilmesi veya optimizasyon için kristalizasyon snf Polietilen glikol 1500 (PEG 4000) PEG 4000 Göz temas nsanlarda göz tahriine neden olmas olas deildir PEG 4000 Cilt temas man.PEG 4000 Soluma Bu malzeme solunduunda tahrie neden olabilir. PEG 4000 Yutma Gastrointestinal sistemde tahrie neden olur. Az yoluyla düük toksisite, ancak yutulmas mide-barsak yolunda tahrie neden olabilir. PEG 4000 Göz temas Göz ykama solüsyonu veya temiz su ile ykayn, göz kapaklarn en az 10 dakika açk tutarak. Tbbi yardm aln PEG 4000 Deri temas Kirlenmi giysileri çkarn. Cildi sabun ve suyla ykayn. Semptomlar geliirse, tbbi yardm aln. PEG 4000 Soluma Hastay maruziyetten çkarn. Hastalk etkileri meydana gelirse tbbi yardm aln. PEG 4000 Yutma Kusturmaya çalmayn. Az suyla çalkalayn ve içmesi için 200-300 ml (yarm litre) su verin. Hastalk etkileri oluursa tbbi yardm aln PEG 4000 leri Tbbi Tedavi Belirtildii gibi semptomatik tedavi ve destekleyici tedavi PEG 4000 Söndürme Ortam Su sisi, alkol köpüü, karbondioksit, kuru kimyasal PEG 4000 Uygun Olmayan Söndürme Ortam Bilinmiyor. PEG 4000 Özel yangn- koruyucu ekipmanla mücadele Yangn koullarnda bamsz bir solunum aparat ve uygun koruyucu giysi giyilmelidir. PEG 4000 Yangn ve patlama tehlikeleri Yancdr ancak hemen tutumaz.
PEG 4000 Renk beyaz
PEG 4000 Kat form
PEG 4000 Koku hafif
PEG 4000 pH yaklak% 5-7% 5 Suda
PEG 4000 Kaynama noktas / kaynama aral (° C) Veri yok.
PEG 4000 Parlama Noktas (ºC)> 260 (açk kap)
PEG 4000 Kendiliinden Tutuma Scakl (ºC) yaklak 420
PEG 4000 Alev Alma Snrlar Veri yok.
PEG 4000 Patlayc Özellikler Veri yok.
PEG 4000 Oksitleyici Özellikler Veri yok.
PEG 4000 Buhar Younluu Veri yok.
PEG 4000 Suda çözünebilirlik
PEG 4000 Dier bileenlerde çözünürlük Birçok organik çözücüde çözünür, uralarda çözünmez :, alifatik hidrokarbonlar
PEG 4000 Bölme Katsays Veri yok.
PEG 4000 Dinamik viskozite (mPa.s) yaklak 30 @ 99 ° C
PEG 4000 Younluk (g / ml) 1.208 @ 20 ° C
PEG 4000 Kararllk Normal koullar altnda kararldr.
PEG 4000 Kullanlacak malzemelerid Güçlü oksitleyici maddeler.
PEG 4000 Kaçnlmas gereken koullar Bilinmiyor
PEG 4000 Tehlikeli bozunma ürünleri Bilinmiyor
PEG 4000 Tehlikeli polimerizasyon Meydana gelmeyecek