POLYETHYLENE GLYCOL 400 (POLETLEN GLKOL 400)
CAS NO:5117-19-1
EC Number:225-856-4
Molecular Formula:C16H34O9
Molecular Weight:370.439 g/mol
SYNONYMS
Octaethylene glycol;5117-19-1;3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol;Octaethyleneglycol;Polyethylene Glycol 400;HO-PEG8-OH;GLZWNFNQMJAZGY-UHFFFAOYSA-N;PE8;2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol;Octanethyl glycol;2-(2-{2-[2-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy )ethan-1-ol;C16H34O9;EINECS 225-856-4;4gs9;PED-diol (n=8);HO-dPEG8-OH;AC1L2VZM;ACMC-1AL8Y;SCHEMBL45160;KSC270I6P;UNII-B697894SGQ;DTXSID3058618;CHEBI:44794;CTK1H0467;KS-00000GUW;MolPort-003-926-911;B697894SGQ;AC1Q5925;ZINC5178830;ANW-31203;SBB061523;AKOS015839805;ACN-050823;MCULE-3002372725;RL03883;AJ-53504;AK112659;AS-19695;BP-21369;CJ-12501;OR322547;SC-43935;AX8146021;DB-051916;KB-234278;LS-191709;TR-018243;CS-0031650;FT-0635546;O0295;ST51047527;Y4953;Octaethylene glycol, >=95% (oligomer purity);117O191;A829142;C-41276;J-511381;I14-16370;2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
POLYETHYLENE GLYCOL 400
PEG 400 (polyethylene glycol 400) is a low-molecular-weight grade of polyethylene glycol. It is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.
CHEMICAL PROPERTIES
PEG 400 is strongly hydrophilic. The partition coefficient of PEG 400 between hexane and water is 0.000015 (log), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of hexane per 1 million parts of PEG 400 in the water layer.[1]
PEG 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons, and is slightly soluble in aliphatic hydrocarbons.
PRODUCT DETAILS & INFORMATION
Polyethylene glycol 400 (PEG400) is a clear, colorless liquid used in many industries and applications. Our PEG400 has all the characteristics of standard petroleum polyethylene glycol, but with the added benefits of being an environmentally friendly product.
Our PEG 400 has a shelf life of up to one year from the date of manufacture when stored in a cool, well-ventilated place. It is biodegradable and not known to be toxic, though you should follow proper industrial hygiene practices during handling.
USES & APPLICATIONS
CASE: Humectant in Inks and Adhesives; Solvent, Dye Carrier in Inks; Modifier and Binder in Latex Paint; Dispersant in Water Based Coatings
Renewable Chemistries: Our PEGS are Bio-Based, Made from Sugar Cane Waste
Lubricants and Greases: Additive in Synthetic Lubricants, Cutting Oil and Hydraulic Fluids
Metal Working Fluids: Acts as a Solvent in Soldering Flux
Personal Care: Used as a Base for Skin Creams and Lotions Acting as a Solvent, Humectant and Lubricant; Solubilizer in Creams, Lotions and Bath Gels
Plastics: Mold Release Agent and External Lubricant
Rubber: Mold Release Agent and Lubricant in Production of Natural and Synthetic Rubber
Soaps and Detergents: Viscosity Modifier and Solvent
Surfactants and Esters: PEG Esters are used as Surfactants
Textiles: Lubricant, Softener, Dye Carrier, Dispersant and Anti-Static Agent
APPLICATIONS AND CHARACTERISTIC
Polyethylene glycol 400 has a molecular weight between 380 and 420 daltons and a viscosity between 7.0 and 8.0 cSt at 99°C. Our product is used in a range of applications, including the manufacture of cosmetics and personal care products, in which it is employed as a solvent, humectant, lubricant and solubilizer. It is used to process textiles and as a plastic and rubber mold-release agent. In paints and inks, it is a binder, dye carrier, humectant and modifier. Esters of PEG 400 are often used as surfactants.
Our high-quality product is versatile enough to support many applications.
PACKAGING
Smaller quantities of PEG 400 are available for immediate purchase in our online store. Choose from one-gallon cans or five-gallon pails, and place your order today. We can also accommodate bulk orders. To request a quote, tell us your requirements using our secure online form, and one of our sales reps will be in touch shortly.
The low-molecular weight liquid polyethylene glycol PEG 400 is an excellent solvent for a large number of substances that do not readily dissolve in water. They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations. It is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power.
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are widely utilized in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.
Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity. It is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs. It is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye. PEG “400” indicates that the average molecular weight of the specific PEG is 400.
PEGylation occurs when PEGs are attached to numerous protein medications, allowing for greater solubility for selected drugs. Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim. In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative
Density: 1.13 g/cm3 (20 °C)
Flash point: >200 °C
gnition temp.: 360 °C DIN 51794
Melting point:5 °C
Ph value: 5 – 7 (100 g/l, H₂O, 20 °C)
Vapor pressure: <0.1 hPa (20 °C)
Viscosity kinematic: 97 – 110 mm2/s (20 °C)
CAS NO:5117-19-1
EC Number:225-856-4
Molekül Formulü:C16H34O9
Molekül Arl:370.439 g/mol
SYNONYMS
Octaethylene glycol;5117-19-1;3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol;Octaethyleneglycol;Polyethylene Glycol 400;HO-PEG8-OH;GLZWNFNQMJAZGY-UHFFFAOYSA-N;PE8;2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol;Octanethyl glycol;2-(2-{2-[2-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethoxy )ethan-1-ol;C16H34O9;EINECS 225-856-4;4gs9;PED-diol (n=8);HO-dPEG8-OH;AC1L2VZM;ACMC-1AL8Y;SCHEMBL45160;KSC270I6P;UNII-B697894SGQ;DTXSID3058618;CHEBI:44794;CTK1H0467;KS-00000GUW;MolPort-003-926-911;B697894SGQ;AC1Q5925;ZINC5178830;ANW-31203;SBB061523;AKOS015839805;ACN-050823;MCULE-3002372725;RL03883;AJ-53504;AK112659;AS-19695;BP-21369;CJ-12501;OR322547;SC-43935;AX8146021;DB-051916;KB-234278;LS-191709;TR-018243;CS-0031650;FT-0635546;O0295;ST51047527;Y4953;Octaethylene glycol, >=95% (oligomer purity);117O191;A829142;C-41276;J-511381;I14-16370;2-[2-[2-[2-[2-[2-[2-(2-hydroxyethyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
POLETLEN GLKOL 400
PEG 400 (polietilen glikol 400), düük moleküler arlkl bir polietilen glikol snfdr. Berrak, renksiz, viskoz bir svdr. Düük toksisitesi nedeniyle PEG 400, çeitli farmasötik formülasyonlarda yaygn olarak kullanlmaktadr.
KMYASAL ÖZELLKLER
PEG 400, güçlü bir ekilde hidrofiliktir. PEG 400 ve heksan arasndaki bölme katsays, su ve heksan ile kartrldnda PEG 400 su tabakasnda 1 milyon PEG 400 için sadece 15 parça heksan olduunu belirten 0.000015 (log) ‘dir. [bir]
PEG 400, su, aseton, alkoller, benzen, gliserin, glikoller ve aromatik hidrokarbonlar içinde çözünür ve alifatik hidrokarbonlarda az çözünür.
ÜRÜN DETAYLARI VE BLG
Polietilen glikol 400 (PEG400) birçok endüstride ve uygulamada kullanlan berrak, renksiz bir svdrPEG400’ümüz standart petrol polietilen glikol özelliklerine sahiptir, ancak ayn zamanda çevre dostu bir ürün olma avantajna sahiptir.
PEG 400 ünitemiz, serin ve iyi havalandrlm bir yerde saklandnda üretim tarihinden itibaren bir yl raf ömrüne sahiptir. Biyobozunur ve toksik olduu bilinmemektedir, ancak kullanm srasnda uygun endüstriyel hijyen uygulamalarn izlemelisiniz.
KULLANIM VE UYGULAMALAR
OLGU: Mürekkepler ve Yaptrclarda Hümektan; Mürekkeplerde Solvent, Boya Tayc; Lateks Boyada Modifiye Edici ve Balayc; Su Bazl Kaplamalarda Dispersant
Yenilenebilir Kimya Maddeleri: PEG’lerimiz eker Kam Atklarndan Yaplm Biyo-Bazl
Yalayclar ve Gresler: Sentetik Yalar, Kesme Ya ve Hidrolik Akkanlarda Katk Maddesi
Metal leme Akkanlar: Lehimleme Ak innda Solvent olarak davranr
Kiisel Bakm: Solvent, Hümektan ve Yalayc olarak görev yapan Cilt Kremleri ve Losyonlar için Baz Olarak Kullanlr; Kremlerde, Losyonlarda ve Banyo Jellerinde Çözücü
Plastikler: Kalp Ayrc ve D Yalayc
Kauçuk: Doal ve Sentetik Kauçuk Üretiminde Kalp Ayrc ve Yalayc
Sabunlar ve Deterjanlar: Viskozite Deitirici ve Çözücü
Yüzey aktif maddeler ve esterler: Yüzey aktif maddeler olarak PEG esterleri kullanlr.
Tekstil: Yalayc, Yumuatc, Boya Tayc, Dispersant ve Anti-Statik Ajan
UYGULAMALAR VE ÖZELLKLER
Polietilen glikol 400, 380 ve 420 dalton arasnda bir moleküler arla ve 99 ° C’de 7.0 ve 8.0 cSt arasnda bir viskoziteye sahiptir. Ürünümüz, içinde solvent, humektan, yalayc ve çözücü olarak kullanld kozmetik ve kiisel bakm ürünleri de dahil olmak üzere bir dizi uygulamada kullanlmaktadr. Tekstili ilemek ve plastik ve kauçuk kalp ayrc olarak kullanlr. Boyalar ve mürekkeplerde, bir balayc, boya tayc, nemlendirici ve deitirici. PEG 400’ün esterleri genellikle yüzey aktif maddeler olarak kullanlr.
Yüksek kaliteli ürünümüz birçok uygulamay destekleyecek kadar çok yönlüdür.
PAKETLEME
Düük moleküler arlkl sv polietilen glikol PEG 400, suda kolayca çözünmeyen çok sayda madde için mükemmel bir çözücüdür. Bu nedenle, sv ve yar kat preparatlarda aktif maddeler ve eksipiyanlar için çözücüler ve çözündürücü maddeler olarak yaygn ekilde kullanlmaktadrlar. PEG’lerin mükemmel solvent gücünden sorumlu olan aktif maddeler ile kompleksler oluturma kabiliyetidir.
Polietilen glikoller (PEG’ler), çeitli türevleri içerebilen ve çeitli ilevlere sahip olabilen younlatrlm etilen oksit ve sudan üretilen ürünlerdir. Birçok PEG türü hidrofilik olduundan, bunlar penetrasyon arttrclar olarak kullanlr ve topikal dermatolojik preparatlarda youn olarak kullanlr. Pek çok iyonik olmayan türevleri ile birlikte PEG’ler, kozmetik ürünlerde yüzey aktif maddeler, emülsifiye ediciler, temizleme maddeleri, nemlendiriciler ve cilt bakm ürünleri olarak yaygn ekilde kullanlmaktadr.
Polietilen glikol 400 (PEG 400), düük seviyeli bir toksisiteye sahip, düük moleküler arlkl bir polietilen glikol snfdr. Çok hidrofiliktir, bu da zayf suda çözünen ilaçlarn çözünürlüünü ve biyoyararlanmn arttrmak için ilaç formülasyonlarnda yararl bir bileen oluturur. Göz kuruluunu takiben yanma, tahri ve / veya rahatszlk hissi veren oftalmik solüsyonlarda kullanlr. PEG “400”, spesifik PEG’in ortalama molekül arlnn 400 olduunu gösterir.
PEG’lerin, birçok ilaç ilacna baland ve seçilen ilaçlarn daha fazla çözünürlüe sahip olduu PEG’lerin ortaya çkt görülür. PEGile edilmi ilaçlarn örnekleri PEG-interferon alfa (Pegintron) ve PEG-filgrastim’dir. Ek olarak, PEG kolonoskopi prosedürleri ve müshil olarak barsak hazrl olarak kullanlabilir.
Younluk: 1,13 g / cm3 (20 ° C)
Parlama noktas:> 200 ° C
Algoritma scakl: 360 ° C DIN 51794
Erime noktas: 5 ° C
Ph deeri: 5 – 7 (100 g / l, H₂O, 20 ° C)
Buhar basnc: <0.1 hPa (20 ° C)
Viskozite kinematik: 97 – 110 mm2 / s (20 ° C)