POLYSORBATE 20 ( POLYSORBAT 20) POLSORBAT 20
IUPAC name: Polyoxyethylene (20) sorbitan monolaurate
Other names: Montanox 20; Polysorbate 20; PEG(20)sorbitan monolaurate; Alkest TW 20; Tween 20
polyethyleneglycol sorbitan monolaurate, Polysorbate 20, Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs; SORBITAN MONOLAURATE POLYETHOXYLATE;Sorbitan monolaurate, ethoxylated;Sorbitan monolaurate, ethoxylated (1-6.5 moles ethoxylated);Sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs., (Z)-; Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.
SORBILENE L/4;Tween 21
SYNONYMS: Tween 20; Polyoxyethylene Sorbitan Monolaurate;POE (20) sorbitan monolaurate; Polysorbate 20;
(1) Polysorbate 20
English name: Polyoxyethylene (20) Sorbitan monolaurate or Polysorbate 20
Code name: Polyoxyethylene sorbitan monolaurate (Tween 20)
Appearance:light yellow to yellow oily liquid
HLB Value: 16.7
CAS number: 9005-64-5
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Polysorbate
polysorbate Français
Polysorbate 20 ChemIDplus
polysorbatum LINGUA LATINA
Synonyms
Polyoxyethylene (20) sorbitan monolaurate
Polyoxyethylene sorbitan monolaurate
Tween 20
CAS Number: 9005-64-5
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
Polysorbate 20
Polyoxyethylene (20) sorbitan monolaurate
CAS: 9005-64-5
An oily liquid derived from PEG-ylated sorbitan (a derivative of sorbitol) esterified with fatty acids.
Other Known Names: PEG(20)sorbitan monolaurate, Alkest TW 20, Tween 20
Molecular Formula: C58H114O26
Applications: pharmaceutical, food additive, detergent, emulsifier, wetting agent
Use: Polysorbate 20 is the essential ingredient for making body and room sprays. It acts as a solubiliser, allowing the oil phase of your formula to disperse and fully incorporate into the water phase. Polysorbate 20 is a solubilizer commonly used to bind fragrance and essential oils with water based products.
JECFA Food Additive:Polyoxyethylene (20) Sorbitan Monolaurate
GSFA Codex: Polyoxyethylene (20) sorbitan monolaurate (432)
DG SANTE Food Additives:polysorbate 20
Use: Our Polysorbate 20 (polyoxyethylene [20] sorbitan monolaurate) is derived from coconut oil. It is a non-toxic, nonionic surfactant/emulsifier and a water-soluble yellowish liquid used as a dispersing agent which allows oil and water to mix without the use of alcohol. It?s a fragrance solubilizer and stabilizer; it lubricates and has a soothing effect on the skin. This skin- safe ingredient is used extensively in oil-in-water emulsions (lotions, conditioners, cream rinses, shampoos, liquid soaps, body polishes or scrubs, etc.) and also for body mists and linen sprays. Will be found as an ingredient in the majority of body toiletries, cosmetics and wipes now in the market. Polysorbates are generally used in combination with other emulsifiers such as mono- and diglycerides or sorbitan monostearates for various purposes such as to disperse flavors and colors, to make essential oils and vitamins soluble and to improve volume and texture in baked goods. Use Polysorbate 20 when very little foaming action (or none at all) is desired in the finished product.
It is a highly hydrophilic surfactant and approved as a food additives. It is a usuful emulsifier, dispersant and solubilizer for aroma chemiclas and oils
Polysorbate 20 is a nonionic, solubilizer, o/w emulsifier, antistat and fiber lubricant used in textile industry, wetting agent, viscosity modifier, suspending agent used in food, cosmetics, drugs, textile and metal working industries, solubilizer for perfumes and flavours, insecticides, herbicides, paints and inks, pharmaceuticals.
Polysorbate 20 (common commercial brand names include Scattics, Alkest TW 20 and Tween 20) is a polysorbate-type nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid.
Its stability and relative nontoxicity allows it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications.
As the name implies the ethoxylation process leaves the molecule with 20 repeat units of polyethylene glycol; in practice these are distributed across 4 different chains, leading to a commercial product containing a range of chemical species.
Biotechnical applications
In biological techniques and sciences, polysorbate 20 has a broad range of applications.
Polysorbate 20 is used as an excipient in pharmaceutical applications to stabilize emulsions and suspensions.
Industrial and domestic applications
Polysorbate 20 is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself.
Polysorbate 20 is also used as wetting agent in rubber balers in the elastomer industry.
Polysorbate 20 has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies
Sorbitan monolaurate, ethoxylated
What is Polysorbate 20?
In its original form, polysorbate is a harmless sorbitol, which is a sugar alcohol. For its use in personal care products, however, it’s treated with ethylene oxide.
Thus, the name “polysorbate 20,” because it’s treated with 20 parts of ethylene oxide.
The result is an ingredient used as an emulsifier in cosmetic creams, lotions, cream deodorant, baby oil, sun lotion, etc. It is used to help mix oil and water.
Polysorbate 20
Tween 20
9005-64-5
Polyoxyethylene (20) sorbitan monolaurate
POLYOXYETHYLENE SORBITAN MONOLAURATE
Polysorbate (INN)
2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
2-{2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl dodecanoate
2-(2-(3,4-Bis(2-hydroxyethoxy)tetrahydrofuran-2-yl)-2-(2-hydroxyethoxy)ethoxy)ethyl dodecanoate
2-[2-[3,4-bis(2-hydroxyethoxy)tetrahydrofuran-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
9005-66-7
Alkest TW 20
Polysorbate 20
Polysorbate 40
Polysorbate 60
Tween 20
Tween 40
Tween 60
POE (6) sorbitol monolaurate
POE(20) sorbitan monolaurate
Ethoxylated Sorbitan monolaurate
POE (20) sorbitan monolaurate
Polyoxyethylenesorbitan monolaurate
PEG-3 SORBITAN STEA- RATE
E432
Polyoxyethylene Sorbitan Monolaurate Kosher
Polyoxyethylene Sorbitan Monolaurate 20 NF
C12 sorbitan monoester, 20 EO (polysorbate 20)
3,6-Anhydro-1-O-[2-(dodecanoyloxy)ethyl]-2,4,5-tris-O-(2-hydroxyethyl)hexitol
1052273-76-3
118955-40-1
Polysorbates are stable to electrolytes and weak acids and bases; gradual saponification occurs with strong acids and bases.
The oleic esters are sensitive to oxidation. Polysorbates are hygroscopic and should be examined for water content prior to use and dried if necessary.
Also, in common with other polyoxyethylene surfactants, prolonged storage can lead to the formation of peroxides.
Being derived mainly from natural materials, many of these versatile surfactants are water-soluble products that are used as emulsifiers, solubilizers, wetting agents, and dispersants throughout the food, cosmetics, and personal care industries.
These surfactants consist primarily of partial fatty acid esters (oleate, stearate or laurate) of sorbitol-derived cyclic ethers (sorbitans and sorbides) polymerized with approximately 20 molecules of ethylene oxide per molecule of polysorbate.
Polysorbate 20 is a lauric acid with an approximate hydrophilic-lipophilic balance of 16.7.
This product can be used as a solubilizing agent in oil-in-water emulsifications as well as a humectant in skin care products.
In addition, polysorbate-20 is frequently used as an indirect additive for food emulsification.
The Food and Drug Administration (FDA) allows polysorbates to be directly added to food as adjuvants and emulsifiers for flavoring agents
Synonyms:
alkamuls PSML-20
cremophor PS 20
emasol L-120V
glycosperse L-20 KFG
hetsorb L-20
kaopan TW-L-120
liposorb L-20
lonzest SML-20
monebatt – 20
mulsifan SML-20
nikkol TL-10
norfox sorbo T-20
peg-20 sorbitan laurate
peg-20 sorbitan monolaurate
polyethylene glycol (20) sorbitan laurate
polyethylene glycol (20) sorbitan monolaurate
polyoxyethylene (20) sorbitan laurate
polyoxyethylene (20) sorbitan monolaurate
rheodol TW-L120
super refined polysorbate 20
T-maz 20K
tween 20
Sorbitol is a white, sweetish, hygroscopic, crystalline sugar alcohol of six-carbon. It is found naturally in various berries and fruits. Or it is prepared synthetically by high-pressure catalytic hydrogenation of glucose sugar derived from cornstarch. It melts at 93 to 98 C depending on the form. It is used as a a sweetening agent, food additive, toothpaste, tobacco, toiletries and in cosmetics. It is used for vitamin-C fermentation. It is used as a excipient and intravenous osmotic diuretic in pharmaceutical fields. It is also used in the manufacture of polyethers for polyurethanes and surfactants. The term sorbitan describes the anhydride form of sorbitol, whose fatty acids are lipophilic whereas sorbitol body is hydrophilic. This bifunctionality in one molecule provides the basic properties useful in cleaners, detergents, polymer additives, and textile industry as emulsifiers, wetting agents, and viscosity modifiers. Sorbitan esters are rather lipophilic (or hydrophobic) surfactants exhibiting low HLB (Hydrophilic-Lipophilic Balance) values; having an affinity for, tending to combine with, or capable of dissolving in lipids (or water-insoluble). While, the ethoxylated sorbitan esters are hydrophilics exhibiting high HLB values; having an affinity for water; readily absorbing or dissolving in water. The type of fatty acid and the mole number of ethylene oxide provides diverse HLB values for proper applications.
HLB numbers describe following characterestics:
<10 : Lipid soluble (or water-insoluble)
>10 : Water Soluble
4-8 : Antifoaming
7-11 : Water-in-oil emulsion
12-16 : Oil-in-water emulsion
11-14 : Good Wetting
12-15 : Good detergency
16-20 : Stabilizing
Sorbitan Fatty Acid Esters
Polyoxyethylene sorbitan esters are synthesized by the addition, via polymerization, of ethylene oxide to sorbitan fatty acid esters.
These nonionic hydrophilic emulsifiers are very effective antistaling agents and, thus, are used in a wide variety of bakery products.
These emulsifiers are much more widely known as the polysorbates, e.g., polysorbate 20, 60, and 80.
Polysorbate 20, 60, and 80 utilize lauric, stearate, and oleate, respectively, for the fatty acid portion of the molecule.
Polysorbate 60 is a monostearate, whereas polysorbate 65 is a tristearate.
HLB values of sorbitan compounds are:
Surfactants
HLB Value
CAS RN
Sorbitan hexastearate ethoxylate EO 6 mole
3.0
Sorbitan isostearate
4.3
Sorbitan laurate
8.6
1338-39-2
Sorbitan monoisostearate ethoxylate EO 20 mole
15.0
66794-58-9
Sorbitan monolaurate ethoxylate EO 20 mole
16.9
9005-64-5
Sorbitan monooleate ethoxylate EO 20 mole
15.0
9005-65-6
Sorbitan monopalmitate ethoxylate EO 20 mole
15.6
9005-66-7
Sorbitan monostearate ethoxylate EO 20 mole
14.9
9005-67-8
Sorbitan monostearate ethoxylate EO 6 mole
9.5
Sorbitan oleate
4.3
1338-43-8
Sorbitan palmitate
6.7
26266-57-9
Sorbitan sesquioleate
4.5
8007-43-0
Sorbitan stearate
4.7
1338-41-6
Sorbitan tetraoleate ethoxylate EO 30 mole
11.5
Sorbitan tetraoleate ethoxylate EO 40 mole
12.5
Sorbitan tetraoleate ethoxylate EO 6 mole
8.5
63089-86-1
Sorbitan tetrastearate ethoxylate EO 60 mole
13.0
66828-20-4
Sorbitan trioleate ethoxylate EO 20 mole
11.0
9005-70-3
Sorbitan trioleate
1.8
26266-58-0
Sorbitan tristearate ethoxylate EO 20 mole
10.5
9005-71-4
Sorbitan tristearate
2.1
26658-19-5