POVIDON IODINE
POVIDONE IODINE
CAS No: 25655-41-8
METATAGS;1-ethenylpyrrolidin2one;moleculariodine;C6H9I2NO;6077718;9183092;9244584;1471;Alphadine;Alphadines;Betadine;Betadines;Betaisodona
;Betaisodonas;Disadine;Disadines;Povidone Iodine;Isodine;Isodines;Pharmadine;Pharmadines;Polyvinylpyrrolidone Iodine;Polyvinylpyrrolidone Iodines;Povidone Iodine;Povidone-Iodine;Povidone-Iodines;Providine;Providines;PVP Iodine;PVP-I;PVP-Iodine;PVP-Iodines;Povidone iodine;Povidone-iodine;Betadine;25655-41-8;PVP iodine;Isodine;PVP-Iodine;PVP-I;Isobetadyne;Bridine;Disphex;Povadyne;Ultradine;Efo-dine;Iodopoly(vinyl pyrrolidinone);Polyvinylpyrrolidone-iodine complex;Iodine-poly(vinylpyrrolidinone);Poly(vinylpyrrolidinone) iodide;Iodinated poly(vinylpyrrolidone);Poly(vinylpyrrolidone)-iodine adduct;Poly(vinylpyrrolidone)-Iodine complex;Poly(vinylpyrrolidinone)-iodine complex;Poly(vinylpyrrolidone) – iodine complex;Polyvinylpyrrolidone compound with iodine;NSC26245;1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine molecular iodine; 1-vinylpyrrolidin-2-one;1-ethenylpyrrolidin-2-one; molecular iodine;Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex;Proviodine;Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]iodine complex;Povidon Iodine;2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine;Iodine-polyvinylpyrrolidone complex;Povadyne® antiseptic;AC1L8YBR;Polyvinylpyrrolidone / iodine;SCHEMBL1652685;1-Vinyl-2-pyrrolidinone polymers;MolPort-003-959-367;NSC28655;MFCD00084483;NSC-26245;NSC-28655;Polyvinylpyrrolidone – iodine complex;AKOS015898248;API0003902;1-Vinyl-2-pyrrolidinone polymer W/iodine;AN-17813;DR001967;HE329280;HE385330;SC-47246;1-ethenyl-2-pyrrolidinone; molecular iodine;Poly(vinylpyrrolidone)-iodine complex 50g;ST51053744;2-Pyrrolidinone, polymers, compd. with iodine;2725-EP2284149A1;Betadine Swab Aid, Betadine Swabsticks, Betadine,ExCel AP;2725-EP2305636A1;2725-EP2305662A1;2725-EP2311829A1;2-Pyrrolidinone, homopolymer, compd. with iodine;A817952;I11-0272;Povidone (iodinated), European Pharmacopoeia (EP) Reference Standard;Povidone-Iodine (Topical Products) (POE vi done EYE oh dyne);Betadine Skin Cleanser, ;Betadine Spray, Betadine Surgical Scrub, ExCel AP, GRX Dyne Scrub, GRX Dyne, NuPrep 5% Povidone-Iodine, Operand Scrub;Antiinfectives;Alkenes;Anti-Infective Agents;Anti-Infective Agents, Local;Eusol;Sodium Hypochlorite;Administration, cutaneous;Iodophors;Chlorine compounds;POVIDONE IODINE PVP I;povidone iodine spray;POVIOD,PVP-Iodine;POVIDONE-IODINE;ANTISEPTIC;Povidone-Iodine Solution, 1% (w/v) Available Iodine;Universal antiseptic agent;1-Vinyl-2-pyrrolidinone polymers, iodine complex ;1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine; Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex ;PVP-I, Poly(vinylpyrrolidone)Iodine complex,Povadyne®antiseptic;pvp1;videne;isodine;braunol;disphex;inadine;betadine;efo-dine;SURGICIDE;BENZYL ISOCYANIDE; METHYL ISOCYANOACETATE; 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE; Tosylmethyl isocyanide; COBALT ETHYLENE DIAMINE CHLORIDE; DICHLORO(ETHYLENEDIAMINE)PLATINUM(II); 2-Pyrrolidinone; POLYMERS; Amiodarone; Amiodarone hydrochloride; Sodium iodide;Povidone iodine; Polyvinylpyrrolidone cross-linked; N-Vinyl-2-pyrrolidone; Complex iodine; 1-Methyl-2-pyrrolidinone; Iodine; Polyvinylpyrrolidone;High quality Povidone Iodine supplier;betadine; isodine; 1-vinyl-2-pyrrolidinone polymers iodine complex; 25655-41-8; BioChemical Antibiotics; Antibiotics; N-S Antibiotics; A to Z SURGICIDE; SURGICIDE(R); SCRUBIDINE; SCRUBIDINE(R); POVIDONE IODINE; povidone iodine; usp24; POLYVINYL PYRROLIDONE POLYMERS IODINE COMPLEX; POLYVINYLPYRROLIDONE IODINE; POLYVINYLPYRROLIDONE-IODINE COMPLEX; PVP-I; PVP-IODINE; ultradine; 1-ethenyl-2-pyrrolidinonehomopolymercompoundwithiodine; 1-vinyl-2-pyrrolidinonepolymer,compd.withiodine; 1-vinyl-2-pyrrolidinonepolymerw/iodine; 2-Pyrrolidinone,1-ethenyl-,homopolymer,compd.withiodine; betaisodona; braunol; braunosanh; disadined.p.; disphex; efo-dine; inadine; iodine-polyvinylpyrrolidonecomplex; poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodinecomplex; polyvinyl povidone-lodine; povidonenlodine; proviodine; traumasept videne; 1-ethenyl-homopolymer compd. with iodine; PVP-I(Povidone-iodine/solution); Povidone; iodine/povidone-iodine solution; PovidoneIodine(Betadine 1-Ethenyl-2-pyrrolidinone homopolymer compound with iron; C6H9I2NO; povadyne antiseptic;9003-39-9; C6H9NOnxI; C6H9NOxxI2; Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex: (Todine solutions); Povidone Iodine, BP, USP, (Polyvinylpyrrolidone-Iodine Complex) Povadyne(R) antiseptic, Pharmaceutical Povidone Iodine; Povidone Iodine Powder; Povidone Iodine Raw Material ;PVP-I POVIDONEODINE,USP ;Polyvinylpyrrolidone-iodine complex;PVP-I Heterocycles;Braunosan H Disadine DP;1-ethenylpyrrolidin-2-one; diiodane;Isodine; Ultradine; 1-Vinyl-2-pyrrolidinone polymers iodine complex;molecular odne;1-ethenyl-homopolymer; compd. with iodine; Betadine; Efo-dine; Polyvinylpyrrolidone-iodine complex; PVP-I; Povidone Iodide full strength;Povidone-iodine; PVP-Iodine; 1-ethenylpyrrolidin-2-one-iodine (1:1); efo-dine;braunol; disphex; inadine;PVP-Iodine;Huntington Laboratories Brand of Povidone Iodine;Huntington Laboratories Brand of.
POVIDONE IODINE
Povidone iodine is an iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The
iodine may be radiolabeled for research purposes.Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and
viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.
Povidone-iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery.It may be used both to disinfect
the skin of the patient and the hands of the healthcare providers. It may also be used for minor wounds. It may be applied to the skin as a liquid or a
powder.
Side effects include skin irritation. If used on large wounds kidney problems, high blood sodium, and metabolic acidosis may occur.It is not recommended in
people who are less than 32 weeks pregnant or taking lithium. Frequent use is not recommended in people with thyroid problems.Povidone-iodine is a chemical
complex of povidone and the element iodine. It contains from 9% to 12% available iodine. It works by releasing iodine which results in the death of a range
of microorganisms.
Povidone-iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of wound infection. It may be used in first aid for
minor cuts, grazes, burns, abrasions and blisters. Povidone-iodine exhibits longer lasting antiseptic effects than tincture of iodine, due to its slow
absorption via soft tissue, making it the choice for longer surgeries. Chlorhexidine provides similar results, but with no toxicity concerns.
Bacteria do not develop resistance to PVP-I.
Consequently, PVP-I has found broad application in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention
of infections in wounds, ulcers, cuts and burns; for the treatment of infections in decubitus ulcers and stasis ulcers; in gynecology for vaginitis
associated with candidal, trichomonal or mixed infections.
POVIDONE IODINE CHEMICAL and PHYSICAL PROPERTIES
Molecular formula: C6H9I2NO
Molecular Weight: 364.953 g/mol
Color: Yellowish-brown amorphous hygroscopic powder
Odor: A slight characteristic odor
Solubility: Soluble in water
Water Solubility : Soluble in water, ethyl alcohol,isopropyl alcohol, polyethylene glycol and glycerol. Insoluble in chloroform, carbon tetrachloride,hexane, acetone and petroleum ether.
pH: Aqueous solutions have a pH near 2 and may be made more neutral (but less stable) by the addition of sodium bicarbonate
Melting point : 300 °C
Boiling point: 217.6°C at 760 mmHg
Flash point: 93.9°C
Vapour Pressur: 0.132mmHg at 25°C
APPLICATION of POVIDONE IODINE
Prophylaxis of skin and mucous membrane antisepsis and surgical and hygienic hand disinfection. Treatment of burns, decubitus, varicose ulcers,dermatomycosis, pyoderma, acne and vaginitis.
PVP-iodine is used as disinfectant in topical formulations such as solutions, ointments, creams, ovula and others. It is applied in gargle solutions,surgical scrubs, in soaps and shampoos.Application areas;
1)Acted as an antiseptic agent against a broad spectrum of microorganisms;
2)Widely used in pharmaceuticals, daily chemicals, agriculture, industry, graziery, etc
skin and equipment disinfectant before injection or surgery
Anti-infection treatment for oral, gynecological, surgival and skin etc.;
Gynecological medicine
Sterilizer, disinfectant in the foodstuff industry and aquaculture, preventing animal diseases.
STORAGE of POVIDONE IODINE
Store in tightly closed original container in a dry, cool and well-ventilated place. Protect from light, including direct sunrays. Keep away from heat, sparks and open flame.
DISPOSAL of POVIDONE IODINE
Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered. Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release. It is recommended that waste minimization be practiced. The best available technology should be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.
POVDON YOT
Povidon iyot, ameliyatta topik antiseptik olarak kullanlan iyodlu polivinil polimeridir ve cilt ve mukoza zararl enfeksiyonlar için de aerosol olarak kullanlr. yot, aratrma amacyla radyoaktif iaretlenebilir.
Povidon-yot, geni mikrop öldürücü aktiviteye sahip bir iyodin ve polivinilpirolidonun (PVP) suda çözünür kompleksi içeren bir iyodofor çözeltisidir. Çözeltideki polivinilpirolidon iyodin (PVPI) kompleksinden yava yava serbest kalan serbest iyot, lipidlerin iyotlanmas ve sitoplazmik ve membran bileiklerinin oksidasyonu yoluyla ökaryotik veya prokaryotik hücreleri öldürür. Bu madde, bakteri, mantar, protozoa ve virüslere kar geni bir mikrop öldürücü etki sergilemektedir. Çözeltideki PVPI kompleksinden yava yava iyot salnmas, memeli hücrelerine kar iyot toksisitesini en aza indirir.
yodopovidon olarak da bilinen Povidon iyot (PVP-I) cerrahi öncesi ve sonras cilt dezenfeksiyonu için kullanlan bir antiseptiktir. Hastann derisini ve salk hizmeti sunucularnn ellerini dezenfekte etmek için kullanlabilir. Küçük yaralar için de kullanlabilir. Deriye sv veya toz olarak uygulanabilir.
Yan etkiler arasnda cilt tahrii bulunur. Büyük yaralar üzerinde kullanldnda böbrek problemleri, yüksek kan sodyum ve metabolik asidoz oluabilir. 32 haftadan az gebe veya lityum kullanan insanlarda önerilmemektedir. Tiroid sorunlar olan insanlarda sk kullanlanlar önerilmemektedir. Povidon iyot, povidonun bir kimyasal kompleksi ve iyod maddesidir. % 9 ila% 12 kullanlabilir iyot içerir. Bir dizi mikroorganizmann ölümüyle sonuçlanan iyot brakarak çalr.
Povidon iyot, yara enfeksiyonunun tedavisinde ve önlenmesinde topikal uygulama için geni spektrumlu bir antiseptiktir. lk yardm için kullanlabilir
Küçük kesikler, sazlar, yanklar, anma ve kabarcklar. Povidon iyot, yumuak doku yoluyla yava emilimi nedeniyle iyot tentüründen daha uzun soluklu antiseptik etkiler sergiler ve bu nedenle daha uzun ameliyatlar için tercih edilir. Klorheksidin benzer sonuç verir, ancak toksisite endieleri yoktur.
Bakteriler PVP-I’e kar direnç gelitirmezler.
Sonuç olarak, PVP-I tpta bir cerrahi frçayla geni uygulama alan bulmutur; Öncesi ve ameliyat sonras cilt temizlii için; Yaralar, ülserler, kesikler ve yanklarda enfeksiyonlarn tedavisi ve önlenmesi için; Dekübitüs ülser ve staz ülserlerinde enfeksiyonlarn tedavisi için; Kandidal, trikomonal veya kark enfeksiyonlarla ilikili vajinit için jinekolojide.
POVDON YOT KMYASAL VE FZKSEL ÖZELLKLER
Moleküler formül: C6H9I2NO
Moleküler Arlk: 364.953 g / mol
Renk: Sar-kahverengi amorf higroskopik toz
Koku: Hafif karakteristik bir koku.
Çözünürlük: Suda çözünür
Suda Çözünürlüü: Su, etil alkol, izopropil alkol, polietilen glikol ve gliserolde çözünür. Kloroform, karbon tetraklorür, hekzan, aseton ve petrol eterinde çözünmez.
PH: Sulu çözeltilerin pH’si 2’ye yakn olup sodyum bikarbonat ilavesiyle daha nötr hale getirilebilir (ancak daha az kararl hale getirilebilir)
Erime noktas: 300 ° C
Kaynama noktas: 760 mmHg’de 217.6 ° C
Parlama noktas: 93.9 ° C
Buhar Basnc: 0.132mmHg, 25 ° C’de
POVDON YOT UYGULANMASI
Deri ve mukoz membran antiseptisinde profilaksi, cerrahi ve hijyenik el dezenfeksiyonu. Yanklarn tedavisi, dekübitüs, varikoz ülseri,
Dermatomikoz, piyoderma, akne ve vajinit.
PVP iyot, çözeltiler, merhemler, kremler, ovula ve dierleri gibi topikal formülasyonlarda dezenfektan olarak kullanlr. Gargara solüsyonlarnda,
Cerrahi frçalar, Sabunlar ve ampuanlar. Uygulama alanlar;
1)Geni bir mikroorganizma yelpazesine kar antiseptik bir madde olarak kullanlr;
2)laç, günlük kimyasallar, tarm, sanayi, graziery vb.
Deri ve ekipman dezenfektann enjeksiyon veya ameliyattan önce
Oral, jinekolojik, cerrahi ve cilt vb. Için enfeksiyon önleme tedavisi;
Jinekolojik tp
Sterilizatör, gda endüstrisinde dezenfektan ve su ürünleri yetitiricilii, hayvan hastalklarn önleme.
POVDON YOT DEPOLAMA
Skca kapal orijinal ambalajnda kuru, serin ve iyi havalandrlan bir yerde saklayn. Direk güne rengi dahil ktan koruyun. Is, kvlcm ve alevden uzak tutun.
POVDON YOT BERTARAFI
Atklar, yürürlükteki tüm kanunlara ve yönetmeliklere uygun olarak atn. Üye Devlete özgü ve Topluluk tarafndan özel hükümler dikkate alnmaldr. Maddenin ilgili bilinen çevresel ve insan sal tehlikelerini dikkate alarak, mesleki maruziyeti ve çevresel salm önlemek için uygun teknik ve prosedürel atk su ve atk bertaraf etme önlemlerini gözden geçirin ve uygulayn. Atk minimizasyonunun uygulanmas önerilir. Çevresel salmlar önlemek için mevcut en iyi teknoloji kullanlmaldr. Bu, atk ve atk su için ykc teknikler içerebilir.