PVP/VA I-535

CAS No. : 25086-89-9

EC No. : 607-540-1

Synonyms:

Vinylpyrrolidone; vinylacetate copolymer; vinyls; polyvinylpyrrolidone and vinylpyrrolidone copolymers (PVP); Polyvinylpyrrolidone/vinyl acetate; Polivinilpirolidon Vinil Asetat; vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; PVP/VA I 535; PVP-VA I 535; PVP VA I 535; PVP/VA I-535; PVP/VA W/735;PVP-VA E-335; PVP-VA E-335; PVP-VA E-735; PVP-VA E-735; PVP-VA I-335; PVP-VA I-535; PVP/VA 37 E; PVP/VA 37 I; PVP/VA 55 E; PVP/VA 55 I; PVP/VA 64 E; PVP/VA E 335; PVP/VA E 535; PVP/VA E 735; PVP/VA E 735; PVP/VA I-735; PVP/VA E-735; PVP/VA E-735; PVP/VA I-735; PVP/VA I-535; PVP/VA E-735; PVP/VA E-535; PVP/VA I-535; PVP/VA I-335; PVP/VA I-735;Luviskol VA 37 E ; Luviskol VA 37 I ; Luviskol VA 55 I ; Luviskol VA 64 P ; Luviskol VA 64 W ; Luviskol VA 73 W ; Luviskol VA 73 E; Luviskol VA 37 E 2; Luviskol VA 37 I ; Luviskol VA 55 I ; Luviskol VA 64 P ; Luviskol VA 64 W ; Luviskol VA 73 W ; Luviskol VA 73 E ethenyl acetate;1-ethenylpyrrolidin-2-one; copovidone; Kollidon VA64; poly(V-co-V-Ac); poly(vinyl pyrrolidone-co-vinyl acetate); poli(vinil pirolidon-ko-vinil asetat); poly(vinylpyrrolidone-co-vinyl-acetate); poli(vinilpirolidon-ko-vinil-asetat); PVP VA64; PVP-VA; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Luviskol VA 281; Gantron S 860; Luviskol VA 28 I; Luviskol VA 37 E; PVP-VA; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-vinylpyrrolidone polymer; vinil asetat-vinilpirolidon polimer; Vinylpyrrolidone-vinyl acetate polymer; vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; PVP-VA I-535; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; 1-vinil pirolidon vinil asetat; acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; ethenyl acetate;1-ethenylpyrrolidin-2-one; poly(1-vinyl pyrrolidone-co-vinyl acetate); VP/VA COPOLYMER, 1-ETHENYL-2-PYRROLIDINONE, POLYMER WITH ACETIC ACID ETHENYL ESTER; 1-ETHENYL-2-PYRROLIDINONE, POLYMER WITH ETHENYL ACETATE; ACETIC ACID ETHENYL ESTER, POLYMER WITH 1ETHENYL2PYRROLIDINONE; ACETIC ACID, ETHENYL ESTER, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE; ETHENYL ACETATE, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE; ETHENYL ESTER POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE ACETIC ACID; POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE ACETIC ACID, ETHENYL ESTER; POLYMER WITH ACETIC ACID ETHENYL ESTER 1-ETHENYL-2-PYRROLIDINONE; POLYMER WITH ETHENYL ACETATE 1-ETHENYL-2-PYRROLIDINONE; PVP/ VA COPOLYMER; PVP/VA COPOLYMER; 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Gantron S 860; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); PVP-VA; Ganex E 535; GAF-S 630; Vinyl acetate-vinylpyrrolidone polymer; Vinylpyrrolidone-vinyl acetate polymer; Luviskol VA 281; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; Luviskol VA 28 I; Luviskol VA 37 E; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-N-vinylpyrrolidinone copolymer; E 535; I 535; I 735; I 735; S 630; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; MFCD00134018; 2-Pyrrolidinone, polymer with ethenyl acetate; AC1L6PLN; AC1Q5XA0; SCHEMBL29127; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; PVP/VA I 535; PVP-VA I 535; PVP VA I 535; PVP/VA I-535; PVP/VA W/735 ; ethenyl acetate;1-ethenylpyrrolidin-2-one; copovidone; Kollidon ; VA64poly(V-co-V-Ac); poly(vinyl pyrrolidone-co-vinyl acetate); poli(vinil pirolidon-ko-vinil asetat); poly(vinylpyrrolidone-co-vinyl-acetate); poli(vinilpirolidon-ko-vinil-asetat); PVP VA64; PVP-VA; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Luviskol VA 281; Gantron S 860; Luviskol VA 28 I; Luviskol VA 37 E; PVP-VA; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-vinylpyrrolidone polymer; vinil asetat-vinilpirolidon polimer; Vinylpyrrolidone-vinyl acetate polymer ;vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; PVP-VA I-535; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer ;Vinyl acetate-N-vinylpyrrolidinone polymer ;Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer;PVP/VA I 535; PVP-VA I 535; PVP VA I 535; PVP/VA I-535; PVP/VA W/735;PVP-VA E-335; PVP-VA E-335; PVP-VA E-735; PVP-VA E-735; PVP-VA I-335; PVP/VA 37 E; PVP/VA 37 I; PVP/VA 55 E; PVP/VA 55 I; PVP/VA 64 E; PVP/VA E 335; PVP/VA E 535; PVP/VA E 735; PVP/VA E 735; PVP/VA I-735; PVP/VA E-735; PVP/VA E-735; PVP/VA I-735; PVP/VA I-535; PVP/VA E-735; PVP/VA E-535; PVP/VA I-535; PVP/VA I-335; PVP/VA I-735;Luviskol VA 37 E ; Luviskol VA 37 I ; Luviskol VA 55 I ; Luviskol VA 64 P ; Luviskol VA 64 W ; Luviskol VA 73 W ; Luviskol VA 73 E; Luviskol VA 37 E 2; Luviskol VA 37 I ; Luviskol VA 55 I ; Luviskol VA 64 P ; Luviskol VA 64 W ; Luviskol VA 73 W ; Luviskol VA 73 E ethenyl acetate;1-ethenylpyrrolidin-2-one; copovidone; Kollidon VA64; poly(V-co-V-Ac); poly(vinyl pyrrolidone-co-vinyl acetate); poli(vinil pirolidon-ko-vinil asetat); poly(vinylpyrrolidone-co-vinyl-acetate); poli(vinilpirolidon-ko-vinil-asetat); PVP VA64; PVP-VA; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E; Luviskol VA 64; Kolima 10; Kolima 35; Vinylpyrrolidone; vinylacetate copolymer; vinyls; polyvinylpyrrolidone and vinylpyrrolidone copolymers (PVP); Polyvinylpyrrolidone/vinyl acetate; Polivinilpirolidon Vinil Asetat; PVP/VA I 535; PVP-VA I 535; PVP VA I 535; PVP/VA I-535; PVP/VA W/735;PVP-VA E-335; PVP-VA E-335; PVP-VA E-735; PVP-VA E-735; PVP-VA I-335; PVP/VA 37 E; PVP/VA 37 I; PVP/VA 55 E; PVP/VA 55 I; PVP/VA 64 E; PVP/VA E 335; PVP/VA E 535; PVP/VA E 735; PVP/VA E 735; PVP/VA I-735; PVP/VA E-735; PVP/VA E-735; PVP/VA I-735; PVP/VA I-535; PVP/VA E-735; PVP/VA E-535; PVP/VA I-535; PVP/VA I-335; PVP/VA I-735;Luviskol VA 37 E ; Luviskol VA 37 I ; Luviskol VA 281; Gantron S 860; Luviskol VA 28 I; Luviskol VA 37 E; PVP-VA; ethenyl acetate- 1-ethenylpyrrolidin-2-one(1:1); Acetic acid vinyl ester, polymer with 1-vinyl-2-pyrrolidinone; Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; Vinyl acetate-vinylpyrrolidone polymer; vinil asetat-vinilpirolidon polimer; Vinylpyrrolidone-vinyl acetate polymer; vinilpirolidon-vinil asetat polimer; Vinyl acetate-vinylpyrrolidinone polymer; Vinyl acetate-vinylpyrrolidone copolymer; Vinylpyrrolidinone-vinyl acetate polymer; Vinylpyrrolidone-vinyl acetate copolymer; N-Vinylpyrrolidone-vinyl acetate polymer; Vinyl acetate-N-vinylpyrrolidone polymer; Vinyl acetate-N-vinylpyrrolidinone polymer; Vinyl acetate-N-vinylpyrrolidone copolymer; Vinyl acetate-vinylpyrrolidinone copolymer; Vinylpyrrolidinone-vinyl acetate copolymer; Vinyl acetate-N-vinylpyrrolidinone copolymer; 1-Vinyl-2-pyrrolidone-vinyl acetate copolymer; 2-Pyrrolidinone, polymer with ethenyl acetate; Vinyl acetate-1-vinyl-2-pyrrolidinone polymer; Vinyl acetate-N-vinyl-2-pyrrolidone copolymer; PVP-VA I-535; Vinyl acetate-N-vinyl-2-pyrrolidinone copolymer; Ethenyl acetate, polymer with 1-ethenyl-2-pyrrolidinone; vinylpyrrolidone vinyl acetate; N-vinylpyrrolidone vinyl acetate; 1-vinylpyrrolidone vinyl acetate; 1-vinil pirolidon vinil asetat; acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone; ethenyl acetate;1-ethenylpyrrolidin-2-one; poly(1-vinyl pyrrolidone-co-vinyl acetate); VP/VA COPOLYMER, 1-ETHENYL-2-PYRROLIDINONE, POLYMER WITH ACETIC ACID ETHENYL ESTER; 1-ETHENYL-2-PYRROLIDINONE, POLYMER WITH ETHENYL ACETATE; ACETIC ACID ETHENYL ESTER, POLYMER WITH 1ETHENYL2PYRROLIDINONE; ACETIC ACID, ETHENYL ESTER, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE; ETHENYL ACETATE, POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE; ETHENYL ESTER POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE ACETIC ACID; POLYMER WITH 1-ETHENYL-2-PYRROLIDINONE ACETIC ACID, ETHENYL ESTER; POLYMER WITH ACETIC ACID ETHENYL ESTER 1-ETHENYL-2-PYRROLIDINONE; POLYMER WITH ETHENYL ACETATE 1-ETHENYL-2-PYRROLIDINONE; PVP/ VA COPOLYMER; PVP/VA COPOLYMER; 25086-89-9; PVP/VA Copolymer; Polectron 845; Luviskol VA 28I; Luviskol VA 37E

PVP/VA I-535 (Polyvinylpyrrolidone Vinyl Acetate)

VP/VA Copolymer. PVP-VA I-535 acts as a film forming agent. PVP-VA I-535 is produced by the free-radical polymerization of monomers in the ratio of 50/50 (VP/VA). Shows good propellant compatibility. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP-VA I-535 finds application in formulating hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP-VA I-535 offers strong & stiff hold, enhanced high humidity curl retention.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.

Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions.

What is PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer?

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel’s, wax’s, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum.

PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties.

This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around.

Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid.

Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations.

Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal.

The advantages of using PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers as film formers are:

• film flexibility

• good adhesion

• water remoistenability

• hardness

These properties make PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates.

• Linear, random copolymers

• Increasing vinyl acetate content – increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg

• Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals

• Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50%

• Adhesive and cohesive properties

• E = ethanol (EtOH), I = isopropanol, W = water, S = solid

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E and I copolymer Series

To fit many application areas, the E and I series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties – water sensitivity, viscosity, softening point, etc.

This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S copolymer

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)

W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution.

VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer.

Plasticizers and Polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing.

Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735 copolymer, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 copolymer and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- 335 copolymer. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymer is less hygroscopic than PVP.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are widely used for their excellent film forming properties in the following applications and markets:

In hot melt adhesives, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are used in a variety of water remoistenable or water removable adhesives as listed

below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists.

Storage and handling

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- and I-series

To fit more application areas, the E- and I-series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties – water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair.

Plasticizers and polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing.

Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-335. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is less hygroscopic than PVP.

Abstract

In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate), N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach).

The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios.

Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods.

As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain.

Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability.

PVP/VA Copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA).

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1]

What is PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer?

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E and I copolymer Series

To fit many application areas, the E and I series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties – water sensitivity, viscosity, softening point, etc.

Storage and handling

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- and I-series

To fit more application areas, the E- and I-series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties – water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA.

The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 70/30 copolymer of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair.

Uses

Medical

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.)

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens.

Technical

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an adhesive in glue stick and hot-melt adhesives

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an emulsifier and disintegrant for solution polymerization

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in aqueous metal quenching

for production of membranes, such as dialysis and water purification filters

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a thickening agent in tooth whitening gels[10]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an additive to Doro’s RNA extraction buffer[citation needed]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a stabilizing agent in all inorganic solar cells[13]

Other uses

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.

As a food additive, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers.

In molecular biology, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) can be used as a blocking agent during Southern blot analysis as a component of Denhardt’s buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR.

In microscopy, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is useful for making an aqueous mounting medium.[16]

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17]

Safety of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)

The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21]

Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) instead.[22][23]

Properties of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings.

A 2014 study found fluorescent properties of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) and its oxidized hydrolyzate.

History of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production.

VP/VA Copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) copolymer in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal.

PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.

PVP/VA I-535 (Polivinilpirolidon Vinil Asetat)

VP/VA Kopolimer. PVP-VA I-535, bir film oluturucu ajan olarak ilev görür. PVP-VA I-535, monomerlerin 50/50 (VP/VA) orannda serbest radikal polimerizasyonu ile üretilir. yi itici uyumluluu gösterir. Cam, plastik ve metale yapan effaf, esnek ve oksijen geçirgen filmler oluturur. PVP-VA I-535, saç spreyleri, renklendiriciler, köpükler, jeller, ekillendirici losyonlar / kremler ve yeni ekillendiriciler gibi saç bakm ürünlerinin formüle edilmesinde uygulama bulur. PVP-VA I-535, güçlü ve sert tutu, gelimi yüksek nem kvrlma tutma özellii sunar.

PVP/VA I-535 (polivinilpirolidon vinil asetat), 70/30 VP/VA orannda monomerler üzerinde serbest radikal polimerizasyonu ile üretilen bir film oluturucudur. Suda% 50 dorusal ve rasgele polivinilpirolidon / vinil asetat (PVP/VA) kopolimer çözeltisidir. PVP/VA W-Serisi kopolimerler, 30/70 ila 40/60 vinil asetat (VA) ile vinilpirolidon (VP) arasnda deien monomerlerin suda salanan serbest radikal polimerizasyonu ile üretilen dorusal, rastgele kopolimerlerdir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.

Polivinilpirolidon / vinil asetat (PVP/VA I-535 (polivinilpirolidon vinil asetat)) reçineleri, 70/30 ila 30/70 vinil asetat ile vinilpirolidon arasnda deien oranlarda monomerlerin serbest radikal polimerizasyonu ile üretilen dorusal, rastgele kopolimerlerdir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri etanol, izopropanol ve su içinde beyaz tozlar veya berrak çözeltiler olarak mevcuttur. Vinilpirolidon içeriinin dört aralndaki polimerler (yüzde 30, 50, 60 ve 70) etanol veya izopropanol içinde üretilir. Yüzde 60 ve 70 vinilpirolidon içeriine sahip PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, katlar veya yüzde 50 sulu çözeltiler olarak mevcuttur.

PVP/VA I-535 (polivinilpirolidon vinil asetat) Kopolimer nedir?

PVP/VA I-535 (polivinilpirolidon vinil asetat) Kopolimer, tutunma faktörünü salayan çou yaygn saç bakm ürününde bulunan bileendir. Bu yüzden çou Saç spreyinde çok yaygndr, ancak ayn zamanda jellerde, ada, pomatlarda ve ekillendirici kremlerde de bulunur. Petrolden elde edilen sentetik bir bileendir.

PVP (Polivinilpirolidon olarak da bilinir), 1950’lerin balarnda gerçekten baarl olan ilk saç spreylerinin ana maddesiydi. Bu polimer, suda çözünür olduu için saç spreyi olarak çalt. Bu, saçnz ykarken durulanabilecei anlamna geliyordu. PVP, havadaki suyu emme eilimindeydi ve saça altmlarda çok yaygn olan o yapkan görünümü verdi.

Bu, polidimetilsiloksan ad verilen bir silikon olan baka bir polimerin yardmyla sabitlendi. Bu silikonun nasl daha iyi bir saç spreyi yaptn anlamak, ilk olarak saç spreyinin nasl çaltn anlamaya yardmc olur. Üzerine püskürttüünüzde, polivinilpirolidon saç üzerinde ince bir tabaka oluturur. Bu kaplama serttir ve saçn hareket etmesini engeller.

Ne yazk ki hiç kimse bu Polimer ile gelen tehlikelerin farknda deildi. PVP/VA I-535 (polivinilpirolidon vinil asetat) Kopolimer partikülleri solunursa, hassas kiilerde akcierlere zarar verebilir. nsanlarn akcierlerindeki yabanc cisimlere partiküller katkda bulunabileceinden toksik olarak kabul edilebilir. Birkaç yl öncesine kadar, bu bileenin kullanmnn güvenli olduu düünülüyordu, ancak imdi kesinlikle kaçnlmas daha iyi bir bileendir.

Burada, bu bileeni HÇBR ürünümüzde ve özellikle de Saç Spreyimizde kullanmyoruz. Greyfurt ve Limon Otu Saç Spreyimiz size sadece nazik olmakla kalmaz, ayn zamanda aerosol içermeyen ve bunun yerine çevre dostu bir tetikleyici sprey bulundurarak çevreye kar da naziktir. Bu güzel ürün, doal bir UV koruyucu ve tutma faktörü içerir, bu da petro-kimyasal, plastik veya polimer olmad anlamna gelir. Bu nazik formül ayn zamanda artk göz ve kafa derisi tahrii olmad anlamna da gelir.

Ashland, formülatörlere bir dizi vinilpirolidon / vinil asetat kopolimeri sunmaktadr. PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimer serisinin üyeleri, farkl derecelerde su direnci talep eden çeitli ürünlerde birincil film oluturucu görevi görür. Bu kopolimerler saç, cilt ve ahap, cam, kat ve metal gibi pürüzsüz yüzeyler için özel afiniteye sahiptir, ancak çkarlmas için çözücülere ihtiyaç duymazlar.

PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerlerini film oluturucu olarak kullanmann avantajlar unlardr:

• film esneklii

• iyi yapma

• suyun yeniden nemlendirilebilirlii

• sertlik

Bu özellikler, PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerlerini çeitli endüstriyel, kiisel bakm ve farmasötik ürünler için uygun hale getirir. Balca endüstriyel uygulamalar, scak eriyik yaptrclar, foto dirençli balayclar ve mürekkep püskürtmeli ortam kad, plastik film ve dier substratlar için kaplamalardr.

• Dorusal, rastgele kopolimerler

• Vinil asetat içeriini artrmak – hidrofobiklii arttrmak, higroskopiklii azaltmak, Tg’yi azaltmak

• Cam, plastik ve metallere yapan hidrofilik, effaf, esnek termoplastik, oksijen geçirgen filmler

• Alkoller, esterler ve ketonlarda çözünür, eterlerde ve alifatik hidrokarbonlarda çözünmez. VP içerii% 50’den fazla olduunda suda çözünür

• Yapkan ve kohezif özellikler

• E = etanol (EtOH), I = izopropanol, W = su, S = kat

PVP/VA I-535 (polivinilpirolidon vinil asetat) E ve I kopolimer Serisi

Birçok uygulama alanna uymas için, E ve I serisi PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri srasyla etanol ve izopropanol2 içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E- 335, E-535, E-635, E-735 ve I grubunda üç tane: 1-335, 1-535, 1-735. Her biri monomer orannda ve dolaysyla özelliklerde farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas vb.

Bu, formülatörlere belirli uygulamalar için yeni ürünler yaratmada önemli ölçüde esneklik salar. Tüm bu kopolimerler tarafndan oluturulan effaf filmler, yapma, parlaklk, sertlik ve su yeniden slanabilirlik ile karakterize edilir. Birçok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek oranl ürünlere göre daha fazla nem direnci sergilemektedir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) S kopolimeri

Beyaz, kokusuz bir toz olan PVP/VA I-535 (polivinilpirolidon vinil asetat) S-630 kopolimeri, 60/40 VP/VA arlk orannda da mevcuttur. Minimum kritik çözelti scakl yaklak 70 ° C olan, yüksek moleküler arlkl, çözücü ve suda çözünür bir kopolimerdir. Çözeltilerden dökülen filmler parlak, yar saydamdr ve su ile yeniden slanabilir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) W kopolimerleri

PVP/VA I-535 (polivinilpirolidon vinil asetat) W-735 kopolimeri, suda% 50 çözelti olarak salanan 70/30 PVP ve vinil asetat kopolimeridir. PVP/VA I-535 (polivinilpirolidon vinil asetat)

W-635 kopolimer, ayrca% 50 sulu çözelti olarak salanan 60/40 kopolimerdir.

VA (vinil asetat), VP’den (vinilpirolidon) daha hidrofobik bir moleküldür. Dolaysyla, kopolimerin artan VA içerii, hidrofobiklikte bir arta ve sonuç olarak VP homopolimerine göre suda çözünürlük ve higroskopide bir azalmaya neden olur.

Plastikletiriciler ve Polimerler: Çou PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimeri, çeitli noniyonik ve katyonik polimerlerle uyumludur. Anyonik kopolimerlerle uyumluluk, kartrma öncesinde nötralizasyon yoluyla salanabilir.

Filmlerin Higroskopiklii: PVP/VA kopolimer filmlerin doal su hassasiyeti, monomer oranna göre deiir. PVP/VA I-535 (polivinilpirolidon vinil asetat) E-735 kopolimeri, PVP/VA I-535 (polivinilpirolidon vinil asetat) E-535 kopolimeri ve PVP/VA I-535 (polivinilpirolidon vinil asetat) E- 335 kopolimeri için tipik veriler aada gösterilmitir. Genel olarak, PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimeri, PVP’den daha az higroskopiktir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, aadaki uygulamalarda ve pazarlarda mükemmel film oluturma özellikleri nedeniyle yaygn olarak kullanlmaktadr:

Scakta eriyen yaptrclarda, PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, listelendii gibi suyla yeniden nemlendirilebilir veya suyla çkarlabilir çeitli yaptrclarda kullanlr.

altnda. Burada formülatörlere film esneklii, yapkanlk ve suyun yeniden nemlendirilebilirliinde performans avantajlar sunarlar.

PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, boya emiciliini artrmak için kat, plastik filmler ve dier substratlar dahil olmak üzere mürekkep püskürtmeli ortam kaplamalarnda da kullanlr. PVP/VA I-535 (polivinilpirolidon vinil asetat) S-630 kopolimeri, fotorezistlerin sulu olarak ilenmesine izin vermek için bir balayc olarak kullanlr.

Saklama ve kullanma

50-55 ° F (10-13 ° C) aralndadr ve yanc (DOT Yanc) malzemeler olarak snflandrlr. Güvenlik nedenleriyle ve scaklk deiiklikleriyle birlikte tambur solumasna bal nem birikmesini önlemek için, 100 ° F (38 ° C) altnda kuru bir yerde saklayn ve patlamaya dayankl tesislerde yeniden paketleyin veya kullann.

PVP/VA I-535 (polivinilpirolidon vinil asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) E- ve I-serisi

Daha fazla uygulama alanna uymas için, E- ve I-serisi PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, srasyla etanol ve izopropanol ** içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E-335, E-535, E-635, E-735 ve I grubunda üç tane: I-335, I-535, I-735. Her biri monomer oran ve dolaysyla özellikleri bakmndan farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas, vb. Bu, formülatörlere özel uygulamalar için yeni ürünler yaratmada önemli ölçüde esneklik salar. Tüm bu kopolimerler tarafndan oluturulan effaf filmler, yapma, parlaklk, sertlik ve su yeniden slanabilirlik ile karakterize edilir. Pek çok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek VP/VA oranlarna sahip ürünlere göre daha fazla nem direnci sergiler.

PVP/VA I-535 (polivinilpirolidon vinil asetat) W kopolimerleri

PVP/VA I-535 (polivinilpirolidon vinil asetat) W-735, suda% 50 çözelti olarak salanan 70/30 PVP ve vinil asetat kopolimeridir. PVP/VA I-535 (polivinilpirolidon vinil asetat) W-635,% 50 sulu çözelti olarak da salanan 60/40 kopolimerdir. Alkolsüz köpükler ve jeller için ideal noniyonik fiksatif reçinelerdir. Formül yapclara saçta birikme, dökülme veya matlama olmadan olaanüstü kvrlma ve stil tutma özellikleri sunarlar.

Plastikletiriciler ve polimerler: Çou PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimeri, çeitli noniyonik ve katyonik polimerlerle uyumludur. Anyonik kopolimerlerle uyumluluk, kartrma öncesinde nötralizasyon yoluyla salanabilir.

Filmlerin higroskopiklii: PVP/VA kopolimer filmlerin doal su hassasiyeti monomer oranna göre deiir. PVP/VA I-535 (polivinilpirolidon vinil asetat) E-735, PVP/VA I-535 (polivinilpirolidon vinil asetat) E-535 ve PVP/VA I-535 (polivinilpirolidon vinil asetat) E-335 için tipik veriler aada gösterilmitir. Genel olarak, PVP/VA I-535 (polivinilpirolidon vinil asetat), PVP’den daha az higroskopiktir.

Öz

Bu çalmada, kopolimer bileiminin ilaç-polimer çözünürlüüne etkisi aratrlmtr. Model ilaç selekoksibin (CCX) çeitli polivinilpirolidon / vinil asetat (PVP/VA I-535 (polivinilpirolidon vinil asetat)) kopolimer bileimlerinde (70/30, 60/40, 50/50 ve 30/70 w / w) ve saf homopolimerlerdeki çözünürlüü polivinilpirolidon (PVP) ve polivinil asetat (PVA), ar doymu bir amorf dispersiyonun yeniden kristalletirilmesine dayanan bir termal analiz yöntemi (yeniden kristalletirme yöntemi) kullanlarak 25 ° C’de tahmin edildi. Bu çözünürlükler, Flory-Huggins kafes teorisi (sv monomer çözünürlüü) kullanlarak, PVP/VA I-535 (polivinilpirolidon vinil asetat), N-vinilpirolidon (NVP) ve vinil asetatn (VA) sv monomerik öncülerindeki CCX çözünürlüüne dayanan bir tahminle karlatrld. yaklamak).

Sv monomer çözünürlük yaklamndan tahmin edilen çözünürlükler, VP/VA orannn 0.03-0.60 w / w’den artmasyla dorusal olarak artt. Yeniden kristalletirme yönteminden tahmin edilen çözünürlükler, 0.02-0.40 w / w’den artan VP/VA oran ile artm olsa da, tahmin edilen çözünürlük yüksek VP/VA oranlarnda bir platoya yaklayor gibi göründü.

Gordon-Taylor denkleminden artan VP/VA oran ile artan pozitif sapmalar, her iki yöntem kullanlarak tahmin edilen nispeten yüksek çözünürlüklere uygun olarak, CCX ve VP tekrar birimi arasnda güçlü etkileimlere iaret etti.

Çözünürlük platosu, CCX ve VP tekrar birimleri arasndaki boyut farkllklarnn neden olduu sterik engelin bir sonucu olabileceinden, bir VP tekrar birimi ile etkileime giren bir CCX molekülünün, baka bir CCX molekülünün içindeki komu tekrar birimlerine balanmasn engellemesi olasdr. polimer zinciri.

Bu nedenle, bu komu higroskopik VP tekrar birimlerinin hidrofobik VA tekrar birimleriyle deitirilmesinin, ilaç-polimer çözünürlüünden ödün vermeden amorf bir kat dispersiyonun fiziksel stabilitesini arttrmas mümkündür. Kopolimerler, optimal ilaç-polimer çözünürlüü ve fiziksel stabilite salamak üzere özelletirilebildiinden, bu bilgi amorf ilaç verme sistemlerinin gelecekteki gelitirilmesinde avantajl bir ekilde kullanlabilir.

PVP/VA Kopolimer. PVP/VA I-535 (polivinilpirolidon vinil asetat), bir film oluturucu ajan olarak ilev görür. Cam, plastik ve metale yapan effaf, esnek ve oksijen geçirgen filmler oluturur. Güçlü ve sert tutu, gelimi yüksek nem kvrlma tutuu ve iyi itici uyumluluu sunar. PVP/VA I-535 (polivinilpirolidon vinil asetat), saç spreyleri, renklendiriciler, köpükler, jeller, ekillendirici losyonlar / kremler ve yeni ekillendiriciler gibi alkolsüz ve saç bakm ürünlerinin formüle edilmesinde uygulama bulur. Suda% 50 dorusal ve rasgele polivinilpirolidon / vinil asetat (PVP/VA) kopolimer çözeltisidir. Monomerlerin 60/40 (VP/VA) orannda serbest radikal polimerizasyonu ile üretilir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) termoplastik, dorusal, rastgele vinilpirolidon / vinilasetat kopolimeri. PVP/VA I-535 (polivinilpirolidon vinil asetat) endüstriyel, özel ve görüntülü kaplamalar, bask mürekkepleri ve boyalarda kullanlr. PVP/VA I-535 (polivinilpirolidon vinil asetat) effaflk, esneklik, oksijen geçirgenlii ve cama, plastiklere ve metallere yapma salar.

PVP/VA I-535 (polivinilpirolidon vinil asetat) endüstriyel olarak 2-pirolidonun vinillenmesi, yani asetilen ile baz katalizli reaksiyonla üretilir. [2] PVP/VA I-535 (polivinilpirolidon vinil asetat), önemli bir sentetik malzeme olan polivinilpirolidonun (PVP) öncüsüdür. PVP/VA I-535 (polivinilpirolidon vinil asetat) monomeri, mürekkep, kaplama veya yaptrc olarak uygulanan ultraviyole ve elektron nyla kürlenebilen polimerlerde reaktif bir seyreltici olarak yaygn olarak kullanlmaktadr. [2] Yaygn olarak polividon veya povidon olarak da adlandrlan polivinilpirolidon (PVP), N-vinilpirolidon monomerinden yaplan suda çözünür bir polimerdir. [1]

PVP/VA I-535 (polivinilpirolidon vinil asetat) Kopolimer nedir?

PVP/VA I-535 (polivinilpirolidon vinil asetat) (Polivinilpirolidon olarak da bilinir), 1950’lerin balarnda gerçekten baarl olan ilk saç spreylerinin ana bileeniydi. Bu polimer, suda çözünür olduu için saç spreyi olarak çalt. Bu, saçnz ykarken durulanabilecei anlamna geliyordu. PVP/VA I-535 (polivinilpirolidon vinil asetat), havadaki suyu emme eilimindeydi ve saça altmlarda çok yaygn olan yapkan bir görünüm kazandrd.

PVP/VA I-535 (polivinilpirolidon vinil asetat) E ve I kopolimer Serisi

Birçok uygulama alanna uymas için, E ve I serisi PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri srasyla etanol ve izopropanol2 içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E- 335, E-535, E-735, E-735 ve I grubunda üç tane: 1-335, 1-535, 1-735. Her biri monomer orannda ve dolaysyla özelliklerde farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas vb.

Saklama ve kullanma

PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, normal depolama koullar altnda en az bir yl stabildir, ancak nem birikmesini önlemek için sk önlemler alnmaldr. E ve I serileri 50-55 ° F (10-13 ° C) aralnda parlama noktalarna sahiptir ve yanc (DOT Yanc) malzemeler olarak snflandrlr. Güvenlik nedenleriyle ve scaklk deiiklikleriyle birlikte tambur solumasna bal nem birikmesini önlemek için, 100 ° F (38 ° C) altnda kuru bir yerde saklayn ve patlamaya dayankl tesislerde yeniden paketleyin veya kullann.

PVP/VA I-535 (polivinilpirolidon vinil asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) E- ve I-serisi

Daha fazla uygulama alanna uymas için, E- ve I-serisi PVP/VA I-535 (polivinilpirolidon vinil asetat) kopolimerleri, srasyla etanol ve izopropanol ** içinde% 50 çözelti olarak mevcuttur. E grubunda dört farkl kopolimer vardr: E-335, E-535, E-735, E-735 ve I grubunda üç tane: I-335, I-535, I-735. Her biri monomer oran ve dolaysyla özellikleri bakmndan farkllk gösterir – su hassasiyeti, viskozite, yumuama noktas, vb. Bu, formülatörlere özel uygulamalar için yeni ürünler yaratmada önemli ölçüde esneklik salar. Tüm bu kopolimerler tarafndan oluturulan effaf filmler, yapma, parlaklk, sertlik ve su yeniden slanabilirlik ile karakterize edilir. Pek çok deitirici ve plastikletirici ile iyi uyumluluk, formülasyonda geni özgürlük salar ve higroskopiklik, film esneklii ve anma direnci araln geniletir. Vinilpirolidonun vinil asetata daha düük oranlarna sahip olan deitirilmemi kopolimerler, yüksek VP/VA oranlarna sahip ürünlere göre daha fazla nem direnci sergiler.

PVP/VA I-535 (polivinilpirolidon vinil asetat) W kopolimerleri

PVP/VA I-535 (polivinilpirolidon vinil asetat) W-735, suda% 50 çözelti olarak salanan PVP/VA I-535 (polivinilpirolidon vinil asetat) ve vinil asetatn 70/30 kopolimeridir. PVP/VA I-535 (polivinilpirolidon vinil asetat) W-735,% 50 sulu çözelti olarak da salanan 60/40 kopolimerdir. Alkolsüz köpükler ve jeller için ideal noniyonik fiksatif reçinelerdir. Formül yapclara saçta birikme, dökülme veya matlama olmadan olaanüstü kvrlma ve stil tutma özellikleri sunarlar.

Kullanmlar

Tbbi

PVP/VA I-535 (polivinilpirolidon vinil asetat), 1950’den sonra travma madurlar için plazma hacim geniletici olarak kullanlmtr. Histamin salnmn provoke etme ve ayn zamanda kan gruplamasna müdahale etme kabiliyeti nedeniyle hacim geniletici olarak tercih edilmemektedir.

PVP/VA I-535 (polivinilpirolidon vinil asetat), birçok farmasötik tablette balayc olarak kullanlr; [2] azdan alndnda basitçe vücuttan geçer. (Bununla birlikte, otopsiler, krospovidonun (PVPP), oral tüketime yönelik farmasötik tabletleri enjekte eden madde bamllarnda pulmoner vasküler hasara katkda bulunduunu bulmutur. [3] Krospovidon veya povidonun akcier içindeki uzun vadeli etkileri bilinmemektedir.)

yoda eklenen PVP/VA I-535 (polivinilpirolidon vinil asetat), dezenfektan özelliklere sahip povidon-iyot ad verilen bir kompleks oluturur. [4] Bu kompleks, solüsyonlar, merhemler, peserler, sv sabunlar ve cerrahi frçalama gibi çeitli ürünlerde kullanlmaktadr. Pyodine ve Betadine ticari isimleri altnda, dierlerinin bolluu arasnda bilinir.

PVP/VA I-535 (polivinilpirolidon vinil asetat) plöredezde kullanlr (sürekli plevral efüzyonlar nedeniyle plevrann füzyonu). Bu amaçla povidon iyot, talk kadar eit derecede etkili ve güvenlidir ve kolay bulunabilirlii ve düük maliyeti nedeniyle tercih edilebilir. [5]

PVP/VA I-535 (polivinilpirolidon vinil asetat), baz kontakt lenslerde ve bunlarn ambalajlama çözümlerinde kullanlr. Sürtünmeyi azaltr, böylece lensin içine yerletirilmi bir kayganlatrc veya slatc olarak ilev görür.

Teknik

PVP/VA I-535 (polivinilpirolidon vinil asetat), stick stick ve hot-melt yaptrclarda yaptrc olarak kullanlr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), piller, seramikler, fiberglas, mürekkepler ve mürekkep püskürtmeli katlar için özel bir katk maddesi olarak ve kimyasal-mekanik düzlemselletirme ileminde kullanlr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), çözelti polimerizasyonu için emülgatör ve parçalayc olarak kullanlr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), katot n tüpleri (CRT) için fotorezistlerde çözünürlüün artmasnda kullanlr [9]

PVP/VA I-535 (polivinilpirolidon vinil asetat), sulu metal söndürmede kullanlr

diyaliz ve su artma filtreleri gibi membran üretimi için

PVP/VA I-535 (polivinilpirolidon vinil asetat), mahsul koruma, tohum ileme ve kaplama gibi tarmsal uygulamalarda balayc ve kompleksletirici ajan olarak kullanlr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), di beyazlatma jellerinde kalnlatrc ajan olarak kullanlmaktadr [10]

PVP/VA I-535 (polivinilpirolidon vinil asetat), sv ve yar sv dozaj formlarnda (uruplar, yumuak jelatin kapsüller) ilaçlarn çözünürlüünü artrmaya yardmc olarak ve yeniden kristalleme inhibitörü olarak kullanlr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), Doro’nun RNA ekstraksiyon tamponuna katk maddesi olarak kullanlr [kaynak belirtilmeli]

PVP/VA I-535 (polivinilpirolidon vinil asetat), DOSY NMR’de sv fazda dispersiyon arttrc ajan olarak kullanlr [11]

PVP/VA I-535 (polivinilpirolidon vinil asetat), nanopartikül sentezinde ve bunlarn kendiliinden birlemesinde yüzey aktif madde, indirgeme ajan, ekil kontrol ajan ve datc olarak kullanlr [12]

PVP/VA I-535 (polivinilpirolidon vinil asetat), tüm inorganik güne pillerinde stabilize edici ajan olarak kullanlmaktadr [13]

Dier kullanmlar

PVP/VA I-535 (polivinilpirolidon vinil asetat), polaritesi nedeniyle polar moleküllere son derece iyi balanr. Bu, fotoraf kalitesinde mürekkep püskürtmeli katlar ve asetatlar için kaplamalarda ve mürekkep püskürtmeli yazclar için mürekkeplerde uygulanmasna yol açmtr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), ampuanlar ve di macunlar gibi kiisel bakm ürünlerinde, eski tip posta pullar ve zarflar gibi nemlendirilmesi gereken boyalarda ve yaptrclarda da kullanlr. Kontakt lens çözümlerinde ve çelik söndürme çözümlerinde de kullanlmtr. [14] [15] PVP/VA I-535 (polivinilpirolidon vinil asetat), saç spreyleri ve saç jelleri için erken formüllerin temelidir ve hala bazlarnn bir bileeni olmaya devam etmektedir.

Bir gda katk maddesi olarak PVP/VA I-535 (polivinilpirolidon vinil asetat), bir stabilizatördür ve E1201 E numarasna sahiptir. PVPP (krospovidon) E1202’dir. Ayrca arap endüstrisinde beyaz arap ve baz biralar için inceltici ajan olarak kullanlr.

Moleküler biyolojide, PVP/VA I-535 (polivinilpirolidon vinil asetat), Denhardt tamponunun bir bileeni olarak Southern blot analizi srasnda bloke edici bir ajan olarak kullanlabilir. Ayrca, DNA saflatrmas srasnda polifenolleri emmede son derece iyidir. Polifenoller birçok bitki dokusunda yaygndr ve uzaklatrlmadklar takdirde proteinleri devre d brakabilir ve bu nedenle PCR gibi birçok aa ak reaksiyonunu inhibe edebilir.

Mikroskopide, PVP/VA I-535 (polivinilpirolidon vinil asetat), sulu bir sabitleme ortam yapmak için kullanldr.

PVP/VA I-535 (polivinilpirolidon vinil asetat), bitki özlerinin insülin üretimi üzerindeki etkisi üzerine 2000 ylnda yaplan bir çalmada belirtildii gibi, fenolik özellikleri taramak için kullanlabilir. [17]

PVP/VA I-535 (polivinilpirolidon vinil asetat) Güvenlii

ABD Gda ve laç Dairesi (FDA) bu kimyasal birçok kullanm için onaylamtr [18] ve genellikle güvenli kabul edilir. Bununla birlikte, PVP / povidona kar, özellikle subkutan (deri altna uygulanan) kullanm ve PVP/VA I-535 (polivinilpirolidon vinil asetat)’in otolog serum (dahili kan svlar) ve mukoza zarlar ile temas ettii durumlar ile ilgili olarak belgelenmi alerjik reaksiyon vakalar vardr. . Örnein, impetigo tedavisi için PVP-yot uygulandktan sonra anafilaktik yant veren bir erkek çocuun, çözeltinin PVP/VA I-535 (polivinilpirolidon vinil asetat) bileenine alerjisi olduu bulundu. [19] Daha önce çeitli saç ürünlerinden ürtiker (kurdeen) yaayan ve daha sonra PVP içerdii tespit edilen bir kadn, dahili olarak povidon-iyot solüsyonu uygulandktan sonra anafilaktik yant ald. PVP’ye alerjisi olduu bulundu. [20] Baka bir vakada, asetaminofen tabletlerini azdan aldktan sonra anafilaksi yaayan bir erkein PVP’ye alerjisi olduu bulundu. [21]

Povidon, yaygn olarak dier kimyasallarla birlikte kullanlr. yot gibi bunlardan bazlar alerjik tepkilerden sorumlu tutulur, ancak baz hastalarda test sonuçlar üpheli kimyasala alerji belirtisi göstermez. Bu dier kimyasallara atfedilen alerjiler muhtemelen PVP/VA I-535 (polivinilpirolidon vinil asetat)’ten kaynaklanyor olabilir. [22] [23]

PVP/VA I-535 (polivinilpirolidon vinil asetat)’in Özellikleri

PVP/VA I-535 (polivinilpirolidon vinil asetat), su ve dier polar çözücüler içinde çözünür. Örnein, metanol ve etanol gibi çeitli alkollerde [24] ve ayrca kolin klorür ve ürenin (Relin) oluturduu derin ötektik çözücü gibi daha egzotik çözücülerde çözünür. [25] Kuruduunda hafif pulsu higroskopik bir tozdur ve arlnn% 40’na kadar atmosferik suda kolayca emilir. Çözelti olarak, mükemmel slatma özelliklerine sahiptir ve kolayca filmler oluturur. Bu, onu bir kaplama veya kaplamalara katk maddesi olarak iyi klar.

2014 ylnda yaplan bir çalmada, PVP/VA I-535 (polivinilpirolidon vinil asetat)’in ve oksitlenmi hidrolizatnn floresan özellikleri bulundu.

PVP/VA I-535 (polivinilpirolidon vinil asetat) Tarihçesi

PVP/VA I-535 (polivinilpirolidon vinil asetat) ilk olarak Walter Reppe tarafndan sentezlendi ve 1939’da asetilen kimyasnn türevlerinden biri için bir patent bavurusu yapld. PVP/VA I-535 (polivinilpirolidon vinil asetat), balangçta bir kan plazmas ikame maddesi olarak ve daha sonra tp, eczaclk, kozmetik ve endüstriyel üretimde çok çeitli uygulamalarda kullanld.

VP/VA Kopolimer. PVP/VA I-535 (polivinilpirolidon vinil asetat) bir film oluturucudur. PVP/VA I-535 (polivinilpirolidon vinil asetat), 70/30 (VP/VA) orannda monomerlerin serbest radikal polimerizasyonu ile üretilir. PVP/VA I-535 (polivinilpirolidon vinil asetat), güçlü ve sert tutu, gelimi yüksek nem kvrlma tutuu ve iyi itici uyumluluu sunar. PVP/VA I-535 (polivinilpirolidon vinil asetat), saç spreyleri, renklendiriciler, köpükler, jeller, ekillendirici losyonlar / kremler ve yeni ekillendiriciler gibi alkolsüz ve saç bakm ürünlerinin formüle edilmesinde uygulama bulur. PVP/VA I-535 (polivinilpirolidon vinil asetat), suda dorusal ve rastgele polivinilpirolidon / vinil asetat (PVP/VA I-535 (polivinilpirolidon vinil asetat)) kopolimerinin% 50’lik bir çözeltisidir. PVP/VA I-535 (polivinilpirolidon vinil asetat), cam, plastik ve metale yapan effaf, esnek ve oksijen geçirgen filmler oluturur.

PVP/VA I-535 (polivinilpirolidon vinil asetat) polimerleri cama, plastiklere ve metallere yapan effaf, esnek, oksijen geçirgen filmler üretir.

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone)

Copolymère VP / VA. PVP-VA I-535 agit comme un agent filmogène. Le PVP-VA I-535 est produit par polymérisation radicalaire de monomères dans le rapport 50/50 (VP / VA). Montre une bonne compatibilité propulsive. Il forme des films transparents, flexibles et perméables à l’oxygène qui adhèrent au verre, au plastique et au métal. Le PVP-VA I-535 trouve une application dans la formulation de produits de soins capillaires tels que des laques, des colorants, des mousses, des gels, des lotions / crèmes coiffantes et des stylers de nouveauté. PVP-VA I-535 offre une tenue solide et rigide, une meilleure rétention des boucles à haute humidité.

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est un filmogène produit par polymérisation radicalaire sur des monomères dans un rapport 70/30 VP / VA. Il s’agit d’une solution à 50% de copolymère linéaire et statistique de polyvinylpyrrolidone / acétate de vinyle (PVP/VA) dans l’eau. Les copolymères PVP/VA série W sont des copolymères aléatoires linéaires produits par polymérisation radicalaire des monomères variant de 30/70 à 40/60 acétate de vinyle (VA) à la vinylpyrrolidone (VP), fournis dans l’eau.

Les polymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) produisent des films transparents, flexibles et perméables à l’oxygène qui adhèrent au verre, aux plastiques et aux métaux.

Les résines polyvinylpyrrolidone / acétate de vinyle (PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone)) sont des copolymères aléatoires linéaires produits par polymérisation radicalaire des monomères dans des rapports variant de 70/30 à 30/70 acétate de vinyle à vinylpyrrolidone.

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont disponibles sous forme de poudres blanches ou de solutions claires dans l’éthanol, l’isopropanol et l’eau. Les polymères dans les quatre gammes de teneur en vinylpyrrolidone (30, 50, 60 et 70 pour cent), sont produits dans l’éthanol ou l’isopropanol. Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) avec une teneur de 60 et 70% de vinylpyrrolidone sont disponibles sous forme de solides ou de solutions aqueuses à 50%.

Qu’est-ce que le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone)?

Le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est l’ingrédient présent dans la plupart des produits de soins capillaires traditionnels qui fournit le facteur de maintien. Il est donc très courant dans la plupart des laques pour cheveux, mais aussi dans les gels, les cires, les pommades et les crèmes coiffantes. C’est un ingrédient synthétique dérivé du pétrole.

La PVP (également connue sous le nom de polyvinylpyrrolidone) était l’ingrédient principal des premiers laques pour cheveux vraiment réussis au début des années 1950. Ce polymère a fonctionné comme un laque pour les cheveux car il était soluble dans l’eau. Cela signifiait qu’il pouvait être rincé lorsque vous vous lavez les cheveux. Le PVP avait tendance à absorber l’eau de l’air, donnant aux cheveux un aspect collant qui était si courant dans les années soixante.

Cela a été corrigé à l’aide d’un autre polymère, un silicone appelé polydiméthylsiloxane. Pour comprendre comment ce silicone a fait une meilleure laque pour les cheveux, il est utile de comprendre comment la laque fonctionne en premier lieu. Lorsque vous le vaporisez, la polyvinylpyrrolidone forme une fine couche sur les cheveux. Ce revêtement est rigide et empêche les cheveux de bouger.

Malheureusement, personne n’était au courant des dangers liés à ce polymère. L’inhalation de particules de copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) peut provoquer des lésions pulmonaires chez les personnes sensibles. Il peut être considéré comme toxique, car les particules peuvent contribuer à la formation de corps étrangers dans les poumons des personnes. Jusqu’à il y a quelques années, cet ingrédient était considéré comme sûr à utiliser, mais il s’agit maintenant d’un ingrédient qu’il vaut mieux éviter.

Chez nous, nous n’utilisons cet ingrédient dans AUCUN de nos produits et surtout pas dans notre laque. Notre fixatif au pamplemousse et à la citronnelle est non seulement gentil avec vous, mais aussi respectueux de l’environnement en ne contenant pas d’aérosol et en ayant plutôt un spray à gâchette respectueux de l’environnement. Ce beau produit contient un protecteur UV naturel et un facteur de maintien, ce qui signifie qu’il n’y a pas de produits pétrochimiques, de plastiques ou de polymères. Cette formule douce signifie également plus d’irritations des yeux et du cuir chevelu.

Ashland propose aux formulateurs une série de copolymères vinylpyrrolidone / acétate de vinyle. Les membres de la série de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) servent de filmogène primaire dans une variété de produits exigeant différents degrés de résistance à l’eau. Ces copolymères présentent une affinité spécifique pour les cheveux, la peau et les surfaces lisses telles que le bois, le verre, le papier et le métal, mais ne nécessitent pas de solvants pour leur élimination.

Les avantages de l’utilisation de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) comme filmogènes sont:

• flexibilité du film

• bonne adhérence

• réhydratation de l’eau

• dureté

Ces propriétés rendent les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) adaptés à une variété de produits industriels, de soins personnels et pharmaceutiques. Les principales applications industrielles sont dans les adhésifs thermofusibles, les liants photorésistants et les revêtements pour papier à jet d’encre, film plastique et autres substrats.

• Copolymères aléatoires linéaires

• Augmentation de la teneur en acétate de vinyle – augmentation de l’hydrophobicité, diminution de l’hygroscopicité, diminution de la Tg

• Films thermoplastiques hydrophiles, transparents, flexibles, perméables à l’oxygène qui adhèrent au verre, aux plastiques et aux métaux

• Soluble dans les alcools, les esters et les cétones, insoluble dans les éthers et les hydrocarbures aliphatiques. Soluble dans l’eau lorsque la teneur en VP est supérieure à 50%

• Propriétés adhésives et cohésives

• E = éthanol (EtOH), I = isopropanol, W = eau, S = solide

Série de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E et I

Pour s’adapter à de nombreux domaines d’application, les séries E et I de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont disponibles sous forme de solutions à 50% dans l’éthanol et dans l’isopropanol2, respectivement. Il existe quatre copolymères distincts dans le groupe E: E-335, E-535, E-635, E-735 et trois dans le groupe I: 1-335, 1-535, 1-735. Chacun diffère par le rapport des monomères et, par conséquent, par les propriétés – sensibilité à l’eau, viscosité, point de ramollissement, etc.

Cela offre aux formulateurs une flexibilité considérable dans la création de nouveaux produits pour des applications spécifiques. Les films transparents formés par tous ces copolymères sont caractérisés par leur adhérence, leur éclat, leur dureté et leur réhumidification à l’eau. Une bonne compatibilité avec de nombreux modificateurs et plastifiants permet une grande liberté de formulation et élargit la gamme d’hygroscopicité, de flexibilité du film et de résistance à l’abrasion. Les copolymères non modifiés ayant les rapports inférieurs de vinylpyrrolidone à l’acétate de vinyle présentent une plus grande résistance à l’humidité que les produits ayant des rapports élevés.

Le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) S

Le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) S-630, une poudre blanche inodore, est également disponible à un rapport pondéral de 60/40 VP / VA. Il s’agit d’un copolymère soluble dans l’eau et à solvant de masse moléculaire élevée présentant une température de solution critique minimale d’environ 70 ° C. Les films coulés à partir de solutions sont brillants, translucides et rémouillables à l’eau.

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W

Le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W-735 est un copolymère 70/30 de PVP et d’acétate de vinyle fourni sous forme d’une solution à 50% dans l’eau. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone)

Le copolymère W-635 est un copolymère 60/40 également fourni sous forme de solution aqueuse à 50%.

VA (acétate de vinyle) est une molécule plus hydrophobe que VP (vinylpyrrolidone). Ainsi, l’augmentation de la teneur en VA du copolymère entraîne une augmentation de l’hydrophobicité et par conséquent une diminution de la solubilité dans l’eau et de l’hygroscopicité par rapport à l’homopolymère VP.

Plastifiants et polymères: La plupart des copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont compatibles avec une variété de polymères non ioniques et cationiques. La compatibilité avec les copolymères anioniques peut être obtenue par neutralisation avant le mélange.

Hygroscopicité des films: La sensibilité à l’eau inhérente des films de copolymère PVP/VA varie avec le rapport des monomères. Des données typiques sont présentées ci-dessous pour le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E-735, le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E-535 et le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E-335. En général, le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est moins hygroscopique que le PVP.

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont largement utilisés pour leurs excellentes propriétés filmogènes dans les applications et les marchés suivants:

Dans les adhésifs thermofusibles, les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont utilisés dans une variété d’adhésifs réhydratables à l’eau ou amovibles à l’eau, comme indiqué.

au dessous de. Ici, ils offrent aux formulateurs des avantages de performance en termes de flexibilité du film, d’adhésivité et de réhumidification de l’eau.

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont également utilisés dans les revêtements pour les supports à jet d’encre, y compris le papier, les films plastiques et d’autres substrats pour améliorer la réceptivité aux colorants. Le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) S-630 est utilisé comme liant pour permettre le traitement aqueux des photorésists.

Stockage et manutention

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont stables pendant au moins un an dans des conditions normales de stockage, mais des précautions strictes doivent être prises pour éviter l’accumulation d’humidité. Les séries E et I ont des points d’éclair compris entre 10 et 13 ° C (50-55 ° F) et sont classées comme matériaux inflammables (DOT inflammables). Pour des raisons de sécurité et pour éviter l’accumulation d’humidité due à la respiration du tambour avec les changements de température, entreposer dans un endroit sec en dessous de 100 ° F (38 ° C) et reconditionner ou utiliser dans des installations antidéflagrantes.

Les séries PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E et I

Pour s’adapter à plus de domaines d’application, les séries E et I de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont disponibles sous forme de solutions à 50% dans l’éthanol et l’isopropanol **, respectivement. Il existe quatre copolymères distincts dans le groupe E: E-335, E-535, E-635, E-735 et trois dans le groupe I: I-335, I-535, I-735. Chacun diffère par le rapport des monomères, et donc par les propriétés – sensibilité à l’eau, viscosité, point de ramollissement, etc. Cela offre aux formulateurs une flexibilité considérable pour créer de nouveaux produits pour des applications spécifiques. Les films transparents formés par tous ces copolymères sont caractérisés par leur adhérence, leur éclat, leur dureté et leur réhumidification à l’eau. Une bonne compatibilité avec de nombreux modificateurs et plastifiants permet une grande liberté de formulation et élargit la gamme d’hygroscopicité, de flexibilité du film et de résistance à l’abrasion. Les copolymères non modifiés ayant les rapports inférieurs de la vinylpyrrolidone à l’acétate de vinyle présentent une plus grande résistance à l’humidité que les produits ayant des rapports élevés de VP à VA.

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W-735 est un copolymère 70/30 de PVP et d’acétate de vinyle fourni sous forme de solution à 50% dans l’eau. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W-635 est un copolymère 60/40 également fourni sous forme de solution aqueuse à 50%. Ce sont des résines fixatives non ioniques idéales pour les mousses et gels sans alcool. Ils offrent aux formulateurs des propriétés exceptionnelles de rétention des boucles et du style sans accumulation, écaillage ou ternissement des cheveux.

Hygroscopicité des films: La sensibilité à l’eau inhérente des films de copolymère PVP/VA varie avec le rapport des monomères. Les données typiques sont présentées ci-dessous pour PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E-735, PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E-535 et PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E-335. En général, le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est moins hygroscopique que le PVP.

Abstrait

Dans cette étude, l’influence de la composition du copolymère sur la solubilité médicament-polymère a été étudiée. La solubilité du médicament modèle célécoxib (CCX) dans diverses compositions de copolymères polyvinylpyrrolidone / acétate de vinyle (PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone)) (70/30, 60/40, 50/50 et 30/70 w / w) et les homopolymères purs la polyvinylpyrrolidone (PVP) et l’acétate de polyvinyle (PVA) ont été prédits à 25 ° C en utilisant une méthode d’analyse thermique basée sur la recristallisation d’une dispersion amorphe sursaturée (méthode de recristallisation). Ces solubilités ont été comparées à une prédiction basée sur la solubilité du CCX dans les précurseurs monomères liquides de PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone), N-vinylpyrrolidone (NVP) et acétate de vinyle (VA), en utilisant la théorie du réseau Flory-Huggins (solubilité des monomères liquides approche).

Les solubilités prédites à partir de l’approche de solubilité des monomères liquides ont augmenté de façon linéaire avec l’augmentation du rapport VP / VA de 0,03 à 0,60 w / w. Même si les solubilités prédites à partir de la méthode de recristallisation augmentaient également avec l’augmentation du rapport VP / VA de 0,02 à 0,40 w / w, la solubilité prédite semblait s’approcher d’un plateau à des rapports VP / VA élevés.

Des écarts positifs croissants par rapport à l’équation de Gordon-Taylor avec un rapport VP / VA croissant ont indiqué de fortes interactions entre le CCX et l’unité de répétition VP, ce qui était conforme aux solubilités relativement élevées prédites en utilisant les deux méthodes.

Comme le plateau de solubilité peut être une conséquence de l’encombrement stérique causé par les différences de taille entre les unités répétées CCX et VP, il est probable qu’une molécule CCX interagissant avec une unité répétée VP empêche une autre molécule CCX de se lier aux unités répétées voisines dans le chaîne polymère.

Par conséquent, il est possible que le remplacement de ces unités répétées VP hygroscopiques voisines par des unités répétées VA hydrophobes puisse augmenter la stabilité physique d’une dispersion solide amorphe sans compromettre la solubilité médicament-polymère. Ces connaissances pourraient être utilisées de manière avantageuse dans le développement futur de systèmes de délivrance de médicaments amorphes car les copolymères pourraient être personnalisés pour fournir une solubilité et une stabilité physique optimales du médicament et du polymère.

Copolymère PVP/VA. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) agit comme un agent filmogène. Il forme des films transparents, flexibles et perméables à l’oxygène qui adhèrent au verre, au plastique et au métal. Il offre une tenue solide et rigide, une meilleure rétention des boucles à haute humidité et une bonne compatibilité avec les propulseurs. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) trouve une application dans la formulation de produits de soins capillaires et sans alcool tels que des laques, des colorants, des mousses, des gels, des lotions / crèmes coiffantes et des stylers novateurs. Il s’agit d’une solution à 50% de copolymère linéaire et statistique de polyvinylpyrrolidone / acétate de vinyle (PVP/VA) dans l’eau. Il est produit par polymérisation radicalaire de monomères dans le rapport 60/40 (VP / VA).

Copolymère vinylpyrrolidone / acétate de vinyle thermoplastique PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) linéaire, aléatoire. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) utilisé dans les revêtements industriels, spécialisés et d’imagerie, les encres d’imprimerie et les peintures. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) offre transparence, flexibilité, perméabilité à l’oxygène et adhérence au verre, aux plastiques et aux métaux.

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est produit industriellement par vinylation de la 2-pyrrolidone, c’est-à-dire la réaction catalysée par une base avec de l’acétylène. [2] PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est le précurseur de la polyvinylpyrrolidone (PVP), une matière synthétique importante. Le monomère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est couramment utilisé comme diluant réactif dans les polymères durcissables aux ultraviolets et par faisceau d’électrons appliqués comme encres, revêtements ou adhésifs. [2] La polyvinylpyrrolidone (PVP), également communément appelée polyvidone ou povidone, est un polymère soluble dans l’eau fabriqué à partir du monomère N-vinylpyrrolidone. [1]

Qu’est-ce que le copolymère PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone)?

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) (également connu sous le nom de polyvinylpyrrolidone) était l’ingrédient principal des premiers laques pour les cheveux vraiment réussis au début des années 1950. Ce polymère a fonctionné comme un laque pour les cheveux car il était soluble dans l’eau. Cela signifiait qu’il pouvait être rincé lorsque vous vous lavez les cheveux. Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) avait tendance à absorber l’eau de l’air, donnant aux cheveux cet aspect collant qui était si courant dans les années soixante.

Série de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E et I

Pour s’adapter à de nombreux domaines d’application, les séries E et I de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont disponibles sous forme de solutions à 50% dans l’éthanol et dans l’isopropanol2, respectivement. Il existe quatre copolymères distincts dans le groupe E: E-335, E-535, E-735, E-735 et trois dans le groupe I: 1-335, 1-535, 1-735. Chacun diffère par le rapport des monomères et, par conséquent, par les propriétés – sensibilité à l’eau, viscosité, point de ramollissement, etc.

Stockage et manutention

Les séries PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) E et I

Pour s’adapter à plus de domaines d’application, les séries E et I de copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) sont disponibles sous forme de solutions à 50% dans l’éthanol et l’isopropanol **, respectivement. Il existe quatre copolymères distincts dans le groupe E: E-335, E-535, E-735, E-735 et trois dans le groupe I: I-335, I-535, I-735. Chacun diffère par le rapport des monomères, et donc par les propriétés – sensibilité à l’eau, viscosité, point de ramollissement, etc. Cela offre aux formulateurs une flexibilité considérable pour créer de nouveaux produits pour des applications spécifiques. Les films transparents formés par tous ces copolymères sont caractérisés par leur adhérence, leur éclat, leur dureté et leur réhumidification à l’eau. Une bonne compatibilité avec de nombreux modificateurs et plastifiants permet une grande liberté de formulation et élargit la gamme d’hygroscopicité, de flexibilité du film et de résistance à l’abrasion. Les copolymères non modifiés ayant les rapports inférieurs de la vinylpyrrolidone à l’acétate de vinyle présentent une plus grande résistance à l’humidité que les produits ayant des rapports élevés de VP à VA.

Les copolymères PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W-735 est un copolymère 70/30 de PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) et d’acétate de vinyle fourni sous forme de solution à 50% dans l’eau. PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) W-735 est un copolymère 60/40 également fourni sous forme de solution aqueuse à 50%. Ce sont des résines fixatives non ioniques idéales pour les mousses et gels sans alcool. Ils offrent aux formulateurs des propriétés exceptionnelles de rétention des boucles et du style sans accumulation, écaillage ou ternissement des cheveux.

Les usages

Médical

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) a été utilisé comme extenseur de volume plasmatique pour les victimes de traumatismes après les années 1950.Il n’est pas préféré comme extenseur de volume en raison de sa capacité à provoquer la libération d’histamine et également à interférer avec le groupage sanguin.

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme liant dans de nombreux comprimés pharmaceutiques, [2] il passe simplement à travers le corps lorsqu’il est pris par voie orale. (Cependant, les autopsies ont montré que la crospovidone (PVPP) contribue à des lésions vasculaires pulmonaires chez les toxicomanes qui ont injecté des comprimés pharmaceutiques destinés à la consommation orale. [3] Les effets à long terme de la crospovidone ou de la povidone dans les poumons sont inconnus.)

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) ajouté à l’iode forme un complexe appelé povidone-iode qui possède des propriétés désinfectantes. [4] Ce complexe est utilisé dans divers produits tels que les solutions, les pommades, les pessaires, les savons liquides et les exfoliants chirurgicaux. Il est connu sous les noms commerciaux Pyodine et Betadine, parmi une pléthore d’autres.

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé dans la pleurodèse (fusion de la plèvre en raison d’épanchements pleuraux incessants). À cette fin, la povidone iodée est tout aussi efficace et sûre que le talc, et peut être préférée en raison de sa disponibilité facile et de son faible coût. [5]

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé dans certaines lentilles de contact et leurs solutions d’emballage. Il réduit le frottement, agissant ainsi comme un lubrifiant, ou agent mouillant, intégré dans la lentille.

Technique

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé en tant qu’adhésif dans les bâtons de colle et les adhésifs thermofusibles

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme additif spécial pour les batteries, la céramique, la fibre de verre, les encres et le papier jet d’encre, ainsi que dans le processus de planarisation chimico-mécanique

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme émulsifiant et désintégrant pour la polymérisation en solution

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé pour augmenter la résolution dans les photorésists pour tubes cathodiques (CRT) [9]

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé dans la trempe aqueuse des métaux

pour la production de membranes, telles que les filtres de dialyse et de purification d’eau

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme liant et agent de complexation dans des applications agricoles telles que la protection des cultures, le traitement des semences et le revêtement

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme agent épaississant dans les gels de blanchiment des dents [10]

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme aide pour augmenter la solubilité des médicaments sous formes posologiques liquides et semi-liquides (sirops, gélules molles) et comme inhibiteur de la recristallisation

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme additif au tampon d’extraction d’ARN de Doro [citation nécessaire]

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme agent améliorant la dispersion en phase liquide en RMN DOSY [11]

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme surfactant, agent réducteur, agent de contrôle de forme et dispersant dans la synthèse des nanoparticules et leur auto-assemblage [12]

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utilisé comme agent stabilisant dans toutes les cellules solaires inorganiques [13]

Autres utilisations

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) se lie exceptionnellement bien aux molécules polaires, en raison de sa polarité. Cela a conduit à son application dans les revêtements pour papiers et transparents à jet d’encre de qualité photo, ainsi que dans les encres pour imprimantes à jet d’encre.

Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est également utilisé dans les produits de soins personnels, tels que les shampooings et les dentifrices, dans les peintures et les adhésifs qui doivent être humidifiés, tels que les timbres-poste et les enveloppes à l’ancienne. Il a également été utilisé dans les solutions pour lentilles de contact et dans les solutions de trempe de l’acier. [14] [15] Le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est à la base des premières formules des sprays capillaires et des gels capillaires, et continue d’en faire partie.

En tant qu’additif alimentaire, le PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est un stabilisant et porte le numéro E E1201. PVPP (crospovidone) est E1202. Il est également utilisé dans l’industrie du vin comme agent de collage du vin blanc et de certaines bières.

En biologie moléculaire, PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) peut être utilisé comme agent de blocage pendant l’analyse par transfert de Southern en tant que composant du tampon de Denhardt. Il est également exceptionnellement bon pour absorber les polyphénols lors de la purification de l’ADN. Les polyphénols sont communs dans de nombreux tissus végétaux et peuvent désactiver les protéines s’ils ne sont pas éliminés et donc inhiber de nombreuses réactions en aval comme la PCR.

En microscopie, PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) est utile pour fabriquer un milieu de montage aqueux. [16]

PVP/VA I-535 (Acétate de Vinyle Polyvinylpyrrolidone) peut être utilisé pour cribler les propriétés phénoliques, comme indiqué dans une étude de 2000 sur l’effet d’extraits de plantes sur la production d’insuline.

PVP/VA I-535

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