TMTD
TMTD, also called Tetramethylthiuram disulfide or Thiram, is mainly used to treat seeds and soil and to prevent and control cereal powdery mildew, smut, and vegetable diseases.
TMTD is used as a fungicide ectoparasiticide to prevent fungal diseases in seeds and crops and, similarly, as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents, and deer.
TMTD has been used in treating human scabies as a sunscreen, and bactericide applied directly to the skin or incorporated into soap.
TMTD is also used as a sulfur source and secondary accelerator for the sulfur vulcanization of rubbers.
TMTD is an organic disulfide that results from the formal oxidative dimerization of N,N-dimethyldithiocarbamic acid.
TMTD is widely used as a fungicidal seed treatment.
TMTD has a role as an antibacterial drug, an antiseptic drug, and an antifungal agrochemical.
EC / List no.: 205-286-2
CAS no.: 137-26-8
Mol. formula: C6H12N2S4
Molecular Formula: C6H12N2S4
(CH3)2N-CS-S-S-CS-N(CH3)2
Synonyms: Arasan; Aules; Bis(dimethylthiocarbamoyl) disulfide; Disulfide, bis(dimethylthiocarbamoyl)-; Mercuran; Nomersan; Pomarsol; Spotrete; Tersan 75; Tetramethyl thiuramdisulfide; Tetramethylthioperoxydicarbonic diamide (((Me2N)C(S))2S2); Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl-; Thiram; thirame; Thylate; Tiram; Tirame; TMTD; Vancide TM-95
Synonym(s): Bis(dimethylthiocarbamoyl) disulfide, Bis(dimethylthiocarbamyl) disulfide, Thiram
Preferred IUPAC name: Dimethylcarbamothioic dithioperoxyanhydride
Chemical formula: C6H12N2S4
Molar mass: 240.42 g·mol−1
Appearance: White to yellow crystalline powder or flake
Odor: Characteristic[vague]
Melting point: 155 to 156 °C (311 to 313 °F; 428 to 429 K)
Boiling point: decomposes
Solubility in water: 30 mg/L
Vapor pressure: 0.000008 mmHg (20 °C)
Chemical properties of TMTD:
Tetramethylthiuram disulfide is a type of sulfur fungicide.
Tetramethylthiuram disulfide has been found to dissolve entirely in chloroform, acetone, and ether.
Tetramethylthiuram disulfide is available as dust, flowable, wettable powder, water-dispersible granules, and water suspension formulations and in mixtures with other fungicides.
Other names: Bis(dimethylthiocarbamoyl) disulfide; Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), tetramethyl-; Disulfide, bis(dimethylthiocarbamoyl); Aapirol; Aatiram; Accel TMT; Accelerator T; Accelerator Thiuram; Aceto TETD; Arasan; Arasan 42S; Arasan 70; Arasan 70-S Red; Arasan 75; Arasan-M; Arasan-SF; Atiram; Bis(dimethylthiocarbamyl) disulfide; Cyuram DS; Ekagom TB; Falitiram; Fernasan; Fernasan A; Fernide; Formalsol; Hermal; Hermat TMT; Heryl; Hexathir; Kregasan; Mercuram; Methyl Tuads; Methyl Thiram; Nobecutan; Normersan; Panoram 75; Polyram ultra; Pomarsol; Pomarsol Forte; Pomasol; Puralin; Rezifilm; Royal TMTD; Sadoplon; Sadoplon 75; Spotrete; SQ 1489; Tersan; Tetramethylthiuram Bisulfide; Tetrasipton; Thillate; Thiosan; Thioscabin; Thiotox; Thiram B; Thiram 75; Thiram 80; Thirasan; Thiulin; Thiurad; Thiuram; Thiuram disulfide, tetramethyl-; Thiuram D; Thiuram M; Thiuramyl; Thylate; Tiuramyl; Trametan; Tridipam; Tripomol; Tuads; TUEX; Tulisan; Tutan; TMTD; TMTDS; Vulcafor TMT; Vulcafor TMTD; Vulkacit thiuram; Vulkacit TH; VUagT-I-4; Zaprawa Nasienna T; Tetramethylthiuram disulphide; α,α’-Dithiobis(dimethylthio)formamide; Arasan-sf-x; Bis(dimethyl-thiocarbamoyl)-disulfid; Bis((dimethylamino)carbonothioyl) disulfide; Disolfuro di tetrametiltiourame; Disulfure de tetramethylthiourame; Fermide; Fernacol; Formamide, 1,1′-dithiobis(N,N-dimethylthio-; Methylthiuram disulfide; N,N-Tetramethylthiuram disulfide; N,N,N’,N’-Tetramethylthiuram disulfide; N,N’-(Dithiodicarbonothioyl)bis(N-methylmethanamine); Nomersan; Teramethylthiuram disulfide; Tersan 75; Tersantetramethyldiurane sulfide; Tetramethyl-thiram disulfid; Tetramethylenethiuram disulfide; Tetramethylthiocarbamoyldisulphide; Tetramethylthioperoxydicarbonic diamide; Tetramethylthioramdisulfide; Tetramethylthiuram; Tetramethylthiurane disulfide; Tetramethylthiurum disulfide; Tetrathiuram disulfide; Thiotex; Thiramad; Thirame; Thiulix; Thiuram M rubber accelerator; Tirampa; Tiuram; Tyradin; Vancida TM-95; Vulkacit MTIC; Accelerant T; Anles; Arasan 50 red; Basultra; Agrichem flowable thiram; Akrochem TMTD; Aules; Chipco thiram 75; ENT-987; Fermide 850; Naftocit thiuram 16; NSC-1771; Perkacit TMTD; Spotrete-F; Spotrete WP 75; Tetrapom; Thimer; Thioknock; Thiuramin; Vancide TM; Vancide TM-95; Vulkazam S; Vulkacit DTMT; Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N’,N’-tetramethyl-; Bis(dimethylaminothiocarbonyl)disulfide; Betoxin; Nocceler TT; Radothiram; Tiradin; Thiram; Robac TMT
Synonyms:
Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2),N,N,N′,N′-tetramethyl-;Disulfide,bis(dimethylthiocarbamoyl);Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2),tetramethyl-;SQ 1489;Accelerator Thiuram;Aceto TETD;Arasan M;Arasan;Arasan-SF;Bis(dimethylthiocarbamoyl) disulfide;Bis(dimethylthiocarbamyl) disulfide;Fernasan;Fernasan A;Hermal;Heryl;Mercuram;Methyl Thiram;Normersan;Panoram 75;Pomarsol;Pomasol;Puralin;Rezifilm;Royal TMTD;Spotrete;Tersan;Tetramethylthiuram bisulfide;N,N,N′,N′-Tetramethylthiuram disulfide;Tetramethylthiuram disulphide;Tetramethylthiuram disulfide;Thiosan;Thiram;Thiram 75;Thiurad;Thiuram;Thiuram M;Thiuram disulfide,tetramethyl-;Thiuramyl;Tiuramyl;TMTD;TMTDS;Thylate;Tridipam;Tuads;Tulisan;Arasan 75;Fernide;Kregasan;Polyram ultra;Sadoplon;Tetrasipton;Thiulin;Tripomol;VUAgT-I-4;Thiuram D;Thiotox;Thillate;Arasan 42S;Thirasan;Arasan 70;Ekagom TB;Nobecutan;Vulcafor TMTD;Vulkacit Th;Sadoplon 75;Accelerator T;Trametan;Hexathir;Zaprawa Nasienna T;Aatiram;Thiram 80;Vulcafor TMT;Vulkacit thiuram;Hermat TMT;Thiram B;AApirol;Atiram;Falitiram;Formalsol;Thioscabin;Arasan 70-S Red;Tutan;Accel TMT;Tyradin;Tersan 75;Pol-Thiuram;TMT;TUEX;Tigam;Rhenogran TMTD;Metiurac;Nocceler TT;Rhodiauram;Thiotox (fungicide);Accelerant T;Ferna-Col;Methyl Tuads;Arasan 50 red;Radothiram;Radotiram;Thiride;Thiuram TMTD;Tetramethylthioperoxydicarbonic diamide;Zupa S 80;Betoxin;Robac TMT;Pomarsol Forte;12680-07-8;12680-62-5;39456-80-9;56645-31-9;66173-72-6;92481-09-9;93196-73-7;200889-05-0;1135443-08-1;2213445-87-3
Uses of TMTD:
1. TMTD belongs to protective fungicides of broad spectrum, with a residual effect period of up to 7d or so.
It is mainly used for dealing with seeds and soil and preventing powdery mildew, smut, and rice seedlings damping off of cereal crops.
It can also be used for some fruit trees and vegetable diseases.
For example, dressing seed with 500g of 50% wettable powder can control rice blast, leaf spot, barley, and wheat smut.
2. As a pesticide, Tetramethylthiuram Disulfide is often called TMTD.
TMTD is mainly used to treat seeds and soil and to prevent and control cereal powdery mildew, smut, and vegetable diseases.
As the super accelerator of natural rubber, synthetic rubber, and latex, this product is often called accelerator TMTD.
Thiram (TMTD) represents a thiuram vulcanization accelerator, accounting for 85% of the total amount of similar products.
Thiram (TMTD) is also the super accelerator of natural rubber, diene synthetic rubber, Ⅱ, R, and EPDM, with the highest utilization rate.
The vulcanization-promoting force of Tetramethylthiuram Disulfide (TMTD) is powerful but not vulcanized without zinc oxide.
3. TMTD is used to manufacture cables, wires, tires, and other rubber products.
4. TMTD is the super accelerator of natural, synthetic, and latex rubber.
5. TMTD is used as the late effect promoter of natural rubber, butadiene rubber, styrene-butadiene rubber, and polyisoprene rubber.
6. TMTD is used for the pest control of rice, wheat, tobacco, sugar beet, grapes, and other crops, as well as for seed dressing and soil treatment.
7. TMTD is suitable for manufacturing natural rubber, synthetic rubber, and latex and can be used as a curing agent.
TMTD is the second accelerator of thiazole accelerators, which can be used as the continuous vulcanization accelerator with other accelerators.
8. TMTD (Tetramethylthiuram Disulfide) can be used as the super-vulcanization accelerator in the rubber industry and is often used with a thiazole accelerator.
TMTD can also be combined with other accelerators as the continuous rubber accelerator.
TMTD can also be used as a curing agent for slowly decomposing out of free sulfur at more than 100 ℃.
Its products have excellent resistance to aging and heat, so it applies to natural and synthetic rubber.
TMTD mainly manufactures tires, tubes, shoes, cables, and other industrial products.
In agriculture, TMTD can be used as a fungicide and insecticide, and it can also be used as a lubricant additive.
9. Production methods from dimethylamine, carbon disulfide, ammonia condensation reaction was dimethyl dithiocarbamate and then the oxidation of hydrogen peroxide to the finished product.
Translated names
thiram (cs)
thiram (da)
Thiram (it)
Thiram (nl)
Thiram (no)
thiram (ISO) bis(dimethylthiokarbamoyl)disulfid (cs)
Thiram (ISO) Bis-(dimethyl-thiocarbamoyl)-disulfid (de)
Thiram (Θιράμη) (el)
thiram tetramethylthiuram disulfide (nl)
thiram tetramethylthiuramdisulfid (da)
thiram δις (διμεθυλο-θειοκαρβαμοϋλ)-δισουλφίδιο (el)
Thirame (fr)
Thiuram (de)
Tiraam (et)
Tiraam tetrametüültiuraamdisulfiid (et)
Tiraami (fi)
Tiraami Tetrametyylitiuraamidisulfidi (fi)
Tiram (es)
Tiram (hr)
Tiram (hu)
Tiram (mt)
Tiram (ro)
Tiram (sl)
Tiram (sv)
tiram (bis dimetilcarbamoil) disolfuro disolfuro di tetrametiltiourame (it)
tiram (ISO) disulfura de tetrametiltiuram (ro)
tiram (ISO) tetrametiltiuram-diszulfid (hu)
tiram disulfuro de tetrametiltiuram disulfuro de bis (N,N-dimetiltiocarbamilo) (es)
tiram tetrametyltiuramdisulfid (no)
tiram tetrametyltiuramdisulfid (sv)
Tiramas (lt)
tiramas (ISO) tetrametiltiuramo disulfidas (lt)
Tirame (pt)
tirame dissulfureto de tetrametiltiurama (pt)
Tirams (lv)
tirám (sk)
tirám (ISO) bis(dimetyltiokarbamoyl)disulfán (sk)
tirāms (ISO) tetrametiltiurāma disulfīds (lv)
Tiuram (pl)
tiuram (ISO) disulfid tetrametylotiuramu (pl)
Тирам (bg)
тирам (ISO) тeтраметилтиурам дисулфид (bg)
IUPAC names
[disulfanediylbis(carbonothioylnitrilo)]tetramethan
[disulfanediylbis(carbonothioylnitrilo)]tetramethane
Bis(dimethylthiocarbamoyl) disulfide
bis(dimethylthiocarbamoyl) disulfide
Bis(dimethylthiocarbamoyl)disulfide
dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
N,N,N’,N’-tetramethyl-Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2)
N,N-diethylcarbamodithioate
N,N-dimethyl[(dimethylcarbamothioyl)disulfanyl]carbothioamide
Tetramethylthiuram Disulfide
tetramethylthiuram disulfide
Tetramethylthiuram disulphide
tetramethylthiuram disulphide
Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N’,N’-tetramethyl-
Thioperoxydicarbonic diamide, tetramethyl-
Thiram
thiram
Thiram
thiram (ISO)
UPV
Trade names
MAT77 B
Thiram P
Registration dossier
thiram
Tetramethylthiuram disulfide
137-26-8
Thiuram
Rezifilm
TMTD
Pomarsol
Thirame
Arasan
Fernasan
Nobecutan
Thirasan
Aapirol
Tersan
Tetrathiuram disulfide
Tetramethylthiuram
Falitiram
Formalsol
Hexathir
Kregasan
Mercuram
Normersan
Sadoplon
Spotrete
Tetrasipton
Thillate
Thiramad
Aatiram
Atiram
Fermide
Fernide
Hermal
Pomasol
Puralin
Thiotox
Thiulin
Thiulix
Heryl
Pomarsol forte
Methyl tuads
Accelerator T
Methyl Thiram
Fernasan A
Tetramethylthiuram disulphide
Nocceler TT
Arasan-M
Bis(dimethylthiocarbamoyl) disulfide
Thiram B
Arasan-SF
Cyuram DS
Ekagom TB
Hermat TMT
Tetramethylenethiuram disulfide
Accel TMT
Accelerator thiuram
Aceto TETD
Radothiram
Royal TMTD
Tetramethyl-thiram disulfid
Fernacol
Sadoplon 75
Tetramethylthiuram bisulfide
Tetrapom
Thioknock
Thirampa
Thiramum
Anles
Arasan-SF-X
Aules
Thimer
Panoram 75
Tetramethylthiouram disulfide
Tetramethylthiurane disulfide
Arasan 70
Arasan 75
Tersan 75
Thiram 75
Thiram 80
Spotrete-F
TMTDS
Arasan 70-S Red
Tetramethylthioperoxydicarbonic diamide
Methylthiuram disulfide
N,N-Tetramethylthiuram disulfide
Metiurac
Micropearls
Nomersan
Thianosan
Cunitex
Delsan
Thimar
Teramethylthiuram disulfide
Tersantetramethyldiurane sulfide
Pol-Thiuram
Arasan 42-S
Tetramethylthiurum disulfide
Disulfure de tetramethylthiourame
Tetrathiuram disulphide
Sranan-sf-X
Hy-Vic
SQ 1489
Chipco thiram 75
Bis(dimethyl-thiocarbamoyl)-disulfid
Orac TMTD
Tetramethylthioramdisulfide
Tetramethyldiurane sulphite
Thiotox (fungicide)
Disulfide, bis(dimethylthiocarbamoyl)
Bis((dimethylamino)carbonothioyl) disulfide
Fermide 850
Tetramethyl thiuramdisulfide
Tetramethylthiocarbamoyldisulphide
Thiuramyl
Thylate
Methyl thiuramdisulfide
Bis(dimethylthiocarbamyl) disulfide
Tetramethyl thiurane disulfide
Bis(dimethyl thiocarbamoyl)disulfide
Thirame [INN-French]
Thiramum [INN-Latin]
Thiuram D
Disolfuro di tetrametiltiourame
Tetramethyl thiurane disulphide
Tetramethylenethiuram disulphide
N,N’-(Dithiodicarbonothioyl)bis(N-methylmethanamine)
RCRA waste number U244
Flo Pro T Seed Protectant
Tetramethylthiuram bisulphide
Tetramethylthiuran disulphide
Tetramethylthiurum disulphide
NSC-1771
Tetramethyl thiuram disulfide
alpha,alpha’-Dithiobis(dimethylthio)formamide
Thiotex
Thiurad
Tirampa
Tiuramyl
Trametan
Tridipam
Tripomol
Tyradin
Tuads
Tutan
Vulkacit mtic
N,N,N’,N’-Tetramethylthiuram disulfide
N,N-Tetramethylthiuram disulphide
Vulkacit thiuram
Thioperoxydicarbonic diamide, tetramethyl-
Thiuram M
Vulkacit TH
Tetramethylthioramdisulfide [Dutch]
Vulcafor TMT
Vulcafor TMTD
Bis((dimethylamino)carbonothioyl) disulphide
FMC 2070
Bis(dimethylthiocarbamoyl) disulphide
Tetramethyl-thiram disulfid [German]
Formamide, 1,1′-dithiobis(N,N-dimethylthio-
Zaprawa Nasienna T
[Me2NC(S)S]2
Vancida tm-95
Disulfuro di tetrametiltiourame
Arasan 42S
TUEX
Disolfuro di tetrametiltiourame [Italian]
Disulfuro di tetrametiltiourame [Italian]
DTXSID5021332
Disulfure de tetramethylthiourame [French]
NSC1771
dimethylcarbamothioylsulfanyl N,N-dimethylcarbamodithioate
Bis(dimethyl-thiocarbamoyl)-disulfid [German]
VUAgT-I-4
NSC-49512
Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), tetramethyl-
NSC-622696
[disulfanediylbis(carbonothioylnitrilo)]tetramethane
Thiuram M rubber accelerator
MLS000069752
MLS002702972
0D771IS0FH
CHEBI:9495
Thiuram disulfide, tetramethyl-
Thiuram-M
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetramethyl-
bis[Dimethylthiocarbamyl] disulfide
NSC49512
CCG-35460
NSC-59637
NSC622696
TNTD
SQ-1489
NCGC00091563-01
SMR000059023
Thioperoxydicarbonic diamide ((H2N)C(S))2S2, tetramethyl-
[dithiobis(carbonothioylnitrilo)]tetramethane
.alpha.,.alpha.’-Dithiobis(dimethylthio)formamide
DTXCID401332
Caswell No. 856
Granuflo
N,N-dimethyl[(dimethylcarbamothioyl)disulfanyl]carbothioamide
Thiuramin
C6H12N2S4
N,N’,N’-Tetramethylthiuram disulfide
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), N,N,N’,N’-tetramethyl-
CAS-137-26-8
Formamide,1′-dithiobis(N,N-dimethylthio-
Bis[(dimethylamino)carbonothioyl] disulfide
Attack [Antifungal]
Thiram [ISO]
NSC59637
CCRIS 1282
HSDB 863
ENT 987
WLN: 1N1 & YUS & SSYUS & N1 & 1
NSC 1771
EINECS 205-286-2
NSC 49512
NSC 59637
RCRA waste no. U244
EPA Pesticide Chemical Code 079801
NSC 622696
BRN 1725821
tiramo
UNII-0D771IS0FH
Basultra
Betoxin
Tiradin
Accelerant T
AI3-00987
Arasan m
Vulkazam S
Thioperoxydicarbonic diamide ([(H2N)C(S)]2S2), N,N,N’,N’-tetramethyl-
Vanguard GF
Vancide TM
Akrochem TMTD
Perkacit TMTD
Vulkacit DTMT
Robac TMT
Rezifilm (TN)
Arasan 50 red
Spotrete WP 75
MFCD00008325
Vancide TM-95
Naftocit thiuram 16
Spectrum_001687
Thiram (USAN/INN)
Agrichem flowable thiram
THIRAM [HSDB]
THIRAM [IARC]
THIRAM [INCI]
THIRAM [USAN]
THIRAM [INN]
Spectrum2_001554
Spectrum3_001592
Spectrum4_000860
Spectrum5_001653
THIRAM [WHO-DD]
THIRAM [MI]
THIRAM [MART.]
bmse000928
EC 205-286-2
NCIMech_000272
cid_5455
NCIOpen2_007854
SCHEMBL21144
BSPBio_003184
KBioGR_001499
KBioSS_002167
4-04-00-00242 (Beilstein Handbook Reference)
BIDD:ER0359
DivK1c_000741
SPECTRUM1503322
SPBio_001428
CHEMBL120563
Thiram [USAN:INN:BSI:ISO]
BDBM43362
HMS502F03
KBio1_000741
KBio2_002167
KBio2_004735
KBio2_007303
KBio3_002684
KUAZQDVKQLNFPE-UHFFFAOYSA-
ENT-987
NINDS_000741
HMS1922A12
HMS2093E03
HMS2234B08
HMS3374C05
Pharmakon1600-01503322
Tetramethylthiuram disulfide, 97%
Tox21_111150
Tox21_201569
Tox21_301102
NSC758454
s2431
STL264104
(dimethylamino){[(dimethylamino)thioxomethyl]disulfanyl}methane-1-thione
AKOS000120200
bis (dimethyl thiocarbamoyl) disulfide
Bis(dimethylaminothiocarbonyl)disulfide
Tox21_111150_1
bis(dimethylaminothiocarbonyl) disulfide
DB13245
KS-5354
NSC-758454
IDI1_000741
QTL1_000082
NCGC00091563-02
NCGC00091563-03
NCGC00091563-04
NCGC00091563-05
NCGC00091563-06
NCGC00091563-07
NCGC00091563-08
NCGC00091563-09
NCGC00091563-10
NCGC00091563-12
NCGC00255002-01
NCGC00259118-01
NCI60_001477
NCI60_006736
SBI-0051813.P002
Thiram, PESTANAL(R), analytical standard
B0486
CS-0012858
FT-0631799
EN300-16677
D06114
D97716
AB00052345_10
Q416572
SR-01000736911
J-006992
J-524968
SR-01000736911-2
Thiram, certified reference material, TraceCERT(R)
BRD-K29254801-001-06-3
Z56754480
F0001-0468
TETRAMETHYLTHIOPEROXYDICARBONIC ACID [(H2N)C(S)]2S2
N,N-Dimethyl[(dimethylcarbamothioyl)-disulfanyl]carbothioamide
1-(dimethylthiocarbamoyldisulfanyl)-N,N-dimethyl-methanethioamide
N,N-dimethylcarbamodithioic acid (dimethylthiocarbamoylthio) ester
InChI=1/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3
N(1),N(1),N(3),N(3)-tetramethyl-2-dithioperoxy-1,3-dithiodicarbonic diamide
N,N-dimethylcarbamodithioic acid [[dimethylamino(sulfanylidene)methyl]thio] ester
TETRAMETHYLTHIOPEROXYDICARBONIC DIAMIDE ((((CH(SUB 3))(SUB 2)N)C(S))(SUB 2)S(SUB 2))